TDR Targets

Basic information

Technical information

TDR Targets ID: 1740083
Name: 2-(4-methylphenyl)benzaldehyde
MW: 196.244 | Formula: C14H12O
H donors: 0 H acceptors: 1 LogP: 3.37 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: O=Cc1ccccc1c1ccc(cc1)C
InChi: 1S/C14H12O/c1-11-6-8-12(9-7-11)14-5-3-2-4-13(14)10-15/h2-10H,1H3
InChiKey: BNZMLIHMNWLHRL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

ZINC01259590

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.072	0.6305	0.7034
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Trypanosoma brucei	protein kinase, putative	0.0245	0.1928	0.3057
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	adapter molecule crk	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine kinase	0.0599	0.5196	0.9996
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	SH2 domain-containing protein	0.0355	0.2943	0.3283
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0088	0.0169
Trypanosoma brucei	C-8 sterol isomerase, putative	0.072	0.6305	1
Brugia malayi	C-terminal src kinase protein 1	0.0245	0.1928	0.3057
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0599	0.5196	0.9996
Brugia malayi	photoreceptor-specific nuclear receptor	0.0057	0.0196	0.0311
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0057	0.0196	0.0311
Brugia malayi	protein-tyrosine kinase	0.0599	0.5196	0.8241
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0245	0.1928	0.2151
Brugia malayi	Tensin	0.0355	0.2943	0.4667
Mycobacterium ulcerans	short chain dehydrogenase	0.1121	1	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0245	0.1928	0.3708
Trypanosoma cruzi	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0067	0.0287	0.0456
Loa Loa (eye worm)	STAT protein	0.0355	0.2943	0.3283
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0057	0.0196	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0473	0.4032	0.4498
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	epidermal growth factor receptor	0.0245	0.1928	0.3708
Entamoeba histolytica	serine/threonine kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	SH2 domain containing protein	0.0599	0.5196	0.8241
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Trypanosoma cruzi	C-8 sterol isomerase, putative	0.072	0.6305	1
Brugia malayi	nuclear receptor RXR	0.0042	0.0059	0.0093
Mycobacterium leprae	conserved hypothetical protein	0.0035	0	0.5
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK/FAK protein kinase	0.0245	0.1928	0.2151
Brugia malayi	hypothetical protein	0.0355	0.2943	0.4667
Echinococcus granulosus	activated cdc42 kinase 1	0.0245	0.1928	0.3708
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Echinococcus multilocularis	transfer RNA-Thr	0.0245	0.1928	0.3708
Echinococcus multilocularis	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0051	0.0144	0.016
Schistosoma mansoni	protein kinase	0.0245	0.193	0.3713
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0287	0.0321
Brugia malayi	RhoGAP domain containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0057	0.0196	0.0377
Entamoeba histolytica	serine/threonine kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0057	0.0196	0.0377
Echinococcus multilocularis	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Toxoplasma gondii	protein kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	coup transcription factor	0.0057	0.0196	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Plasmodium falciparum	protein kinase, putative	0.0245	0.1928	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Echinococcus multilocularis	tyrosine protein kinase shark	0.06	0.5198	1
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0057	0.0196	0.0377
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0245	0.1928	0.2151
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0245	0.1928	0.3708
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0057	0.0196	0.0219
Loa Loa (eye worm)	TK/CSK protein kinase	0.0245	0.1928	0.2151
Echinococcus granulosus	raf serine:threonine protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Echinococcus granulosus	SHC transforming protein 3	0.0355	0.2943	0.5661
Brugia malayi	Tyrosine-protein kinase abl-1	0.0599	0.5196	0.8241
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus multilocularis	SH2 motif	0.0355	0.2943	0.5661
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Entamoeba histolytica	SH2 domain containing protein	0.0355	0.2943	0.541
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0355	0.2943	0.5661
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0245	0.1928	0.3057
Giardia lamblia	Kinase, NEK	0.0245	0.1928	0.9986
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0355	0.2943	0.5661
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Brugia malayi	Tyrosine-protein kinase PR2	0.0245	0.1928	0.3057
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Schistosoma mansoni	suppressor of cytokine signaling	0.0355	0.2943	0.5661
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0355	0.2943	0.5661
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0045	0.0088	0.0169
Echinococcus multilocularis	SH2 domain containing protein 7	0.0355	0.2943	0.5661
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0245	0.1928	0.3708
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0226	0.1754	0.1754
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0057	0.0196	0.0377
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0287	0.0713
Loa Loa (eye worm)	SH2 domain-containing protein	0.0355	0.2943	0.3283
Brugia malayi	Receptor family ligand binding region containing protein	0.0248	0.1962	0.3112
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0057	0.0196	0.0377
Echinococcus multilocularis	ankyrin repeat protein	0.0162	0.1167	0.2245
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0057	0.0196	0.0311
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	ankyrin repeat protein	0.0245	0.1928	0.3342
Toxoplasma gondii	STE kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	protein kinase	0.0245	0.193	0.3713
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0245	0.1928	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0245	0.1928	0.3057
Echinococcus granulosus	ephrin type A receptor 4 A	0.0245	0.1928	0.3708
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0599	0.5196	0.9996
Brugia malayi	hypothetical protein	0.0042	0.0059	0.0093
Brugia malayi	Nuclear hormone receptor-like 1	0.0057	0.0196	0.0311
Echinococcus multilocularis	integrin linked protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0059	0.0066
Brugia malayi	hypothetical protein	0.0599	0.5196	0.8241
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus multilocularis	SHC transforming protein 3	0.0355	0.2943	0.5661
Echinococcus multilocularis	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Echinococcus multilocularis	epidermal growth factor receptor	0.0245	0.1928	0.3708
Brugia malayi	Furin-like cysteine rich region family protein	0.0245	0.1928	0.3057
Echinococcus multilocularis	protein tyrosine kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0599	0.5196	0.9996
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0059	0.0066
Schistosoma mansoni	ephrin receptor	0.0245	0.1928	0.3708
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0245	0.1928	0.2151
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0248	0.1962	0.2189
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0355	0.2943	0.5661
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	serine/threonine protein kinase	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0057	0.0196	0.0311
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0245	0.1928	0.2151
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0599	0.5196	0.9996
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0045	0.0088	0.0169
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Toxoplasma gondii	3-oxo-5-alpha-steroid 4-dehydrogenase	0.0067	0.0287	0.0713
Brugia malayi	hydrolase, alpha/beta fold family protein	0.0501	0.4286	0.6798
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	nuclear hormone receptor	0.0057	0.0196	0.0377
Schistosoma mansoni	tyrosine kinase	0.0599	0.5196	0.9996
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	ephrin receptor 1 precursor	0.0245	0.1928	0.3057
Onchocerca volvulus		0.0355	0.2943	0.3283
Echinococcus multilocularis	activated cdc42 kinase 1	0.0245	0.1928	0.3708
Echinococcus multilocularis	tensin	0.0355	0.2943	0.5661
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Plasmodium falciparum	protein kinase, putative	0.0245	0.1928	1
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Schistosoma mansoni	serine/threonine RGC	0.0245	0.1928	0.3708
Leishmania major	protein kinase, putative	0.0245	0.1928	0.3057
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/DDR protein kinase	0.0245	0.1928	0.2151
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0245	0.1928	0.3057
Entamoeba histolytica	serine/threonine kinase, putative	0.0245	0.1928	0.3342
Onchocerca volvulus		0.0245	0.1928	0.2151
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0245	0.1928	0.3057
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Brugia malayi	STAT protein, DNA binding domain containing protein	0.0355	0.2943	0.4667
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0245	0.1928	0.2151
Echinococcus multilocularis	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	glutamate (NMDA) receptor subunit	0.0074	0.0357	0.0688
Brugia malayi	Raf kinase	0.0245	0.1928	0.3057
Entamoeba histolytica	ankyrin repeat protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0045	0.0088	0.0169
Schistosoma mansoni	transient receptor potential cation channel subfamily A member	0.0162	0.1167	0.2245
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0245	0.1928	0.2151
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Loa Loa (eye worm)	serine/threonine protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Trypanosoma brucei	Pseudokinase, putative	0.0245	0.1928	0.3057
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0355	0.2943	0.5661
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Entamoeba histolytica	serine/threonine kinase, putative	0.0245	0.1928	0.3342
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0245	0.1928	0.3708
Leishmania major	protein kinase, putative	0.0245	0.1928	0.3057
Echinococcus granulosus	tyrosine kinase	0.0599	0.5196	0.9996
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0057	0.0196	0.0219
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Onchocerca volvulus	Bile acid receptor homolog	0.0536	0.4611	0.5144
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Brugia malayi	Protein kinase domain containing protein	0.0599	0.5196	0.8241
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0057	0.0196	0.0311
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0245	0.1928	0.3057
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Plasmodium falciparum	tyrosine kinase-like protein	0.0245	0.1928	1
Toxoplasma gondii	protein kinase domain-containing protein	0.0245	0.1928	0.4781
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	protein kinase, putative	0.0355	0.2943	0.541
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0599	0.5196	0.5796
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	tensin-related	0.0355	0.2943	0.5661
Echinococcus granulosus	tyrosine protein kinase pr2	0.0245	0.1928	0.3708
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0473	0.4032	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0599	0.5196	0.9996
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Echinococcus multilocularis	FL cytokine receptor	0.0245	0.1928	0.3708
Schistosoma mansoni	tensin	0.0355	0.2943	0.5661
Trichomonas vaginalis	CAMK family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Echinococcus granulosus	tyrosine kinase	0.0248	0.1962	0.3775
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0057	0.0196	0.0377
Brugia malayi	3-oxo-5-alpha-steroid 4-dehydrogenase 1	0.0473	0.4032	0.6395
Echinococcus multilocularis	tensin	0.0355	0.2943	0.5661
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	FTZ F1 alpha	0.0057	0.0196	0.0377
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0245	0.1928	0.3057
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0599	0.5196	0.9996
Schistosoma mansoni	glutamate receptor NMDA	0.0074	0.0357	0.0688
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0245	0.1928	0.3708
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0473	0.4032	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Echinococcus multilocularis	synaptic glycoprotein sc2	0.0067	0.0287	0.0553
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0355	0.2943	0.541
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0599	0.5196	0.9996
Echinococcus multilocularis	protein kinase	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0245	0.1928	0.3708
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0057	0.0196	0.0311
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Echinococcus granulosus	synaptic glycoprotein sc2	0.0067	0.0287	0.0553
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Giardia lamblia	Protein 21.1	0.0245	0.1928	0.9986
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0355	0.2943	0.3283
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0245	0.1928	0.4781
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Schistosoma mansoni	signal transduction protein lnk-related	0.0355	0.2943	0.5661
Echinococcus multilocularis	N chimaerin	0.0355	0.2943	0.5661
Brugia malayi	hypothetical protein	0.0042	0.0059	0.0093
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0245	0.1928	0.2151
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0599	0.5196	0.9996
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0355	0.2943	0.5661
Echinococcus multilocularis	SH2 motif	0.0355	0.2943	0.5661
Trichomonas vaginalis	TK family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	SH2 domain containing protein 7	0.0355	0.2943	0.5661
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0245	0.1928	0.4781
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0599	0.5196	1
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Echinococcus granulosus	insulin receptor	0.0245	0.1928	0.3708
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0057	0.0196	0.0219
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0599	0.5196	0.9996
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Trypanosoma cruzi	protein kinase, putative	0.0245	0.1928	0.3057
Echinococcus granulosus	tyrosine protein kinase Srms	0.0599	0.5196	0.9996
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0245	0.1928	0.3342
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Echinococcus multilocularis	heat shock protein 70	0.0245	0.1928	0.3708
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0355	0.2943	0.3283
Echinococcus granulosus	natriuretic peptide receptor 1	0.0245	0.1928	0.3708
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0245	0.1928	0.2151
Brugia malayi	steroid hormone receptor	0.0057	0.0196	0.0311
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0057	0.0196	0.0377
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK/EPH protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0042	0.0059	0.0113
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	cysteine surface protein, putative	0.0245	0.1928	0.3342
Brugia malayi	Guanylyl cyclase protein 23	0.0248	0.1962	0.3112
Brugia malayi	Variant SH3 domain containing protein	0.0355	0.2943	0.4667
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Echinococcus multilocularis	transient receptor potential cation channel	0.0167	0.1215	0.2337
Trichomonas vaginalis	synaptic glycoprotein sc2, putative	0.0067	0.0287	0.0713
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Schistosoma mansoni	tyrosine kinase	0.0248	0.1962	0.3775
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	hypothetical protein	0.0355	0.2943	0.5661
Schistosoma mansoni	tyrosine kinase	0.0599	0.5196	0.9996
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0059	0.0066
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0245	0.1928	0.3057
Echinococcus granulosus	activated cdc42 kinase 1	0.0245	0.1928	0.3708
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0245	0.1928	0.3708
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0057	0.0196	0.0219
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0057	0.0196	0.0377
Brugia malayi	tRNA modification GTPase TrmE family protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Echinococcus granulosus	receptor type guanylyl cyclase	0.0248	0.1962	0.3775
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0248	0.1962	0.3775
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0355	0.2943	0.3283
Brugia malayi	Nuclear hormone receptor-like 1	0.0042	0.0059	0.0093
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Onchocerca volvulus		0.0599	0.5196	0.5796
Entamoeba histolytica	receptor protein kinase, putative	0.0245	0.1928	0.3342
Trypanosoma cruzi	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0473	0.4032	0.6395
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0057	0.0196	0.0377
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Echinococcus granulosus	integrin linked protein kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	N chimaerin	0.0355	0.2943	0.5661
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Loa Loa (eye worm)	steroid hormone receptor	0.0057	0.0196	0.0219
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0067	0.0287	0.0713
Echinococcus granulosus	growth factor receptor bound protein 2	0.0355	0.2943	0.5661
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trypanosoma brucei	3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative	0.0473	0.4032	0.6395
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0057	0.0196	0.0377
Schistosoma mansoni	tyrosine kinase	0.0599	0.5196	0.9996
Schistosoma mansoni	thyroid hormone receptor	0.0057	0.0196	0.0377
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Protein kinase domain containing protein	0.0599	0.5196	0.8241
Brugia malayi	hypothetical protein	0.0245	0.1928	0.3057
Schistosoma mansoni	protein kinase	0.0248	0.1962	0.3775
Onchocerca volvulus		0.0067	0.0287	0.0321
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0042	0.0059	0.0113
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Brugia malayi	SRC-1	0.0599	0.5196	0.8241
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0248	0.1962	0.2189
Schistosoma mansoni	GTPase activating protein	0.0355	0.2943	0.5661
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	Nuclear hormone receptor-like 1	0.0042	0.0059	0.0093
Schistosoma mansoni	nck2/grb4	0.0355	0.2943	0.5661
Echinococcus granulosus	c src tyrosine kinase	0.0599	0.5196	0.9996
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0245	0.1928	0.3708
Echinococcus granulosus	ankyrin repeat protein	0.0162	0.1167	0.2245
Leishmania major	C-8 sterol isomerase-like protein	0.072	0.6305	1
Echinococcus granulosus	3 oxo 5 alpha steroid 4 dehydrogenase C terminal	0.0067	0.0287	0.0553
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0245	0.1928	0.3708
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0245	0.1928	1
Onchocerca volvulus		0.0355	0.2943	0.3283
Plasmodium falciparum	protein kinase, putative	0.0245	0.1928	1
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	cytokine inducible SH2-containing protein 5	0.0355	0.2943	0.4667
Giardia lamblia	Kinase, NEK	0.0245	0.193	1
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Plasmodium vivax	polyprenol reductase, putative	0.0067	0.0287	0.1491
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0599	0.5196	0.9996
Brugia malayi	SH2 domain containing protein	0.0599	0.5196	0.8241
Toxoplasma gondii	3-oxo-5-alpha-steroid 4-dehydrogenase	0.0473	0.4032	1
Loa Loa (eye worm)	TK/ACK protein kinase	0.0245	0.1928	0.2151
Echinococcus granulosus	tyrosine kinase	0.0599	0.5196	0.9996
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0355	0.2943	0.5661
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Echinococcus granulosus	tyrosine protein kinase shark	0.06	0.5198	1
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0355	0.2943	0.5661
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	ecdysone induced protein 78C	0.0057	0.0196	0.0377
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK/INSR protein kinase	0.0245	0.1928	0.2151
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	ERG2 and Sigma1 receptor like protein	0.072	0.6305	1
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	protein tyrosine kinase	0.0245	0.1928	0.3708
Plasmodium falciparum	tyrosine kinase-like protein	0.0245	0.1928	1
Giardia lamblia	Kinase	0.0245	0.1928	0.9986
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	nuclear hormone receptor	0.0057	0.0196	0.0311
Schistosoma mansoni	tyrosine kinase	0.0248	0.1962	0.3775
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0355	0.2943	0.3283
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0057	0.0196	0.0311
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0599	0.5196	0.9996
Schistosoma mansoni	tyrosine protein kinase	0.0245	0.1928	0.3708
Brugia malayi	ecdysteroid receptor	0.0536	0.4611	0.7313
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Onchocerca volvulus		0.0355	0.2943	0.3283
Brugia malayi	Steroid receptor seven-up type 2	0.0057	0.0196	0.0311
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0355	0.2943	0.3283
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0245	0.1928	0.3708
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0287	0.0713
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0245	0.1928	0.3708
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0245	0.1928	0.3057
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0599	0.5196	0.9996
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0355	0.2943	0.5661
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	tyrosine protein kinase HCK	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Brugia malayi	Variant SH3 domain containing protein	0.0355	0.2943	0.4667
Onchocerca volvulus		0.0245	0.1928	0.2151
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Variant SH3 domain containing protein	0.0355	0.2943	0.4667
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Entamoeba histolytica	tyrosin kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	growth factor receptor-bound protein	0.0355	0.2943	0.5661
Echinococcus multilocularis	tyrosine kinase	0.0599	0.5196	0.9996
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus multilocularis	protein kinase	0.0245	0.1928	0.3708
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0045	0.0088	0.0169
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0355	0.2943	0.5661
Onchocerca volvulus		0.0355	0.2943	0.3283
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/FER protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	serine/threonine protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	SH2 domain-containing protein	0.0355	0.2943	0.3283
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	hypothetical protein	0.0355	0.2943	0.5661
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0245	0.1928	0.3708
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0245	0.1928	0.2151
Echinococcus granulosus	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0088	0.0169
Echinococcus granulosus	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Schistosoma mansoni	tensin	0.0355	0.2943	0.5661
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine kinase	0.0599	0.5196	0.9996
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0355	0.2943	0.5661
Echinococcus granulosus	transient receptor potential cation channel	0.0167	0.1212	0.2332
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0245	0.1928	0.3708
Echinococcus multilocularis	NCK adaptor protein	0.0355	0.2943	0.5661
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0355	0.2943	0.5661
Schistosoma mansoni	shc transforming protein	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Protein kinase domain containing protein	0.0599	0.5196	0.8241
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0599	0.5196	0.9996
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Leishmania major	hypothetical protein, conserved	0.0245	0.1928	0.3057
Entamoeba histolytica	hypothetical protein, conserved	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TK/RYK protein kinase	0.0245	0.1928	0.2151
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0057	0.0196	0.0219
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0042	0.0059	0.0113
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Echinococcus granulosus	tyrosine protein kinase	0.0245	0.1928	0.3708
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0057	0.0196	0.0219
Entamoeba histolytica	steroid 5-alpha reductase, putative	0.0473	0.4032	0.7629
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0245	0.1928	0.2151
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0057	0.0196	0.0311
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Trichomonas vaginalis	AGC family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0245	0.1928	0.3057
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0057	0.0196	0.0377
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0245	0.1928	0.3708
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0248	0.1962	0.2189
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0355	0.2943	0.5661
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0355	0.2943	0.5661
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0599	0.5196	0.9996
Schistosoma mansoni	tensin	0.0355	0.2943	0.5661
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus multilocularis	signal transduction protein lnk realted	0.0355	0.2943	0.5661
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0245	0.1928	0.3057
Echinococcus granulosus	tyrosine protein kinase csk	0.0245	0.1928	0.3708
Schistosoma mansoni	ephrin receptor	0.0245	0.1928	0.3708
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0355	0.2943	0.5661
Schistosoma mansoni	protein tyrosine kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Entamoeba histolytica	receptor protein kinase, putative	0.0245	0.1928	0.3342
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Trichomonas vaginalis	STE family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0059	0.0066
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0057	0.0196	0.0311
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0355	0.2943	0.5661
Schistosoma mansoni	serine/threonine protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	hypothetical protein	0.0248	0.1962	0.2189
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0245	0.1928	0.3708
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0599	0.5196	0.9996
Trichomonas vaginalis	synaptic glycoprotein sc2, putative	0.0067	0.0287	0.0713
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Schistosoma mansoni	hypothetical protein	0.0355	0.2943	0.5661
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0057	0.0196	0.0377
Loa Loa (eye worm)	hydrolase	0.1008	0.8964	1
Echinococcus multilocularis		0.0355	0.2943	0.5661
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0245	0.1928	0.3708
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Schistosoma mansoni	synaptic glycoprotein sc2 related	0.0067	0.0287	0.0553
Echinococcus granulosus	epidermal growth factor receptor	0.0245	0.1928	0.3708
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Echinococcus granulosus	activin receptor type	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Toxoplasma gondii	3-oxo-5-alpha-steroid 4-dehydrogenase	0.0067	0.0287	0.0713
Onchocerca volvulus		0.0599	0.5196	0.5796
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	epidermal growth factor receptor	0.0245	0.1928	0.3708
Echinococcus granulosus	tyrosine protein kinase Blk	0.0599	0.5196	0.9996
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0059	0.0066
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0355	0.2943	0.5661
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0057	0.0196	0.0219
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Onchocerca volvulus		0.0355	0.2943	0.3283
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0045	0.0088	0.0098
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Loa Loa (eye worm)	hypothetical protein	0.0599	0.5196	0.5796
Onchocerca volvulus		0.0355	0.2943	0.3283
Onchocerca volvulus		0.0245	0.1928	0.2151
Echinococcus multilocularis	c src tyrosine kinase	0.0599	0.5196	0.9996
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0599	0.5196	0.9996
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0599	0.5196	0.9996
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0355	0.2943	0.5661
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	suppressor of cytokine signaling	0.0355	0.2943	0.5661
Echinococcus multilocularis	3 oxo 5 alpha steroid 4 dehydrogenase, C terminal	0.0067	0.0287	0.0553
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0599	0.5196	0.5796
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Brugia malayi	Variant SH3 domain containing protein	0.0355	0.2943	0.4667
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Onchocerca volvulus		0.0599	0.5196	0.5796
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0057	0.0196	0.0311
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0042	0.0059	0.0066
Mycobacterium leprae	Probable lipase LipE	0.0035	0	0.5
Trypanosoma cruzi	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0473	0.4032	0.6395
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	tyrosin kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	Synaptic glycoprotein SC2	0.0067	0.0287	0.0456
Echinococcus multilocularis	ecdysone induced protein 78C	0.0057	0.0196	0.0377
Onchocerca volvulus	Tyrosine kinase homolog	0.0245	0.1928	0.2151
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0599	0.5196	0.9996
Brugia malayi	hypothetical protein	0.0245	0.1928	0.3057
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0045	0.0088	0.0169
Brugia malayi	Sex muscle abnormal protein 5	0.0355	0.2943	0.4667
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0057	0.0196	0.0311
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0248	0.1962	0.2189
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	SH2 motif	0.0355	0.2943	0.5661
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Schistosoma mansoni	serine/threonine protein kinase	0.0245	0.1928	0.3708
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0245	0.1928	0.3708
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TK/ABL protein kinase	0.0599	0.5196	0.5796
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0355	0.2943	0.3283
Loa Loa (eye worm)	hypothetical protein	0.0051	0.0144	0.016
Echinococcus granulosus	signal transduction protein lnk realted	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0245	0.1928	0.3057
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Onchocerca volvulus		0.0245	0.1928	0.2151
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0057	0.0196	0.0377
Brugia malayi	Protein kinase domain containing protein	0.0599	0.5196	0.8241
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0245	0.1928	0.3057
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0057	0.0196	0.0219
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0051	0.0144	0.0228
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0051	0.0144	0.0228
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0245	0.1928	0.3708
Onchocerca volvulus	Protein ultraspiracle homolog	0.0057	0.0196	0.0219
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	integrin-linked kinase	0.0245	0.1928	0.3057
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0045	0.0088	0.014
Echinococcus multilocularis	FTZ F1 alpha	0.0057	0.0196	0.0377
Echinococcus granulosus	protein kinase	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0599	0.5196	0.5796
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	hypothetical protein	0.0067	0.0287	0.0321
Schistosoma mansoni	tyrosine kinase	0.06	0.5198	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0196	0.0219
Onchocerca volvulus		0.0245	0.1928	0.2151
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0355	0.2943	0.5661
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	thyroid hormone receptor	0.0057	0.0196	0.0377
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Plasmodium vivax	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0067	0.0287	0.1491
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0245	0.1928	0.3708
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Trypanosoma brucei	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0067	0.0287	0.0456
Leishmania major	3-oxo-5-alpha-steroid 4-dehydrogenase-like protein	0.0473	0.4032	0.6395
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Brugia malayi	Protein kinase domain containing protein	0.0599	0.5196	0.8241
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0245	0.1928	0.3057
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Entamoeba histolytica	serine/threonine kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	vav2	0.0355	0.2943	0.5661
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0245	0.1928	0.4781
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0057	0.0196	0.0377
Entamoeba histolytica	protein kinase domain containing protein	0.0245	0.1928	0.3342
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK/ROR protein kinase	0.0245	0.1928	0.2151
Echinococcus granulosus	NCK adaptor protein	0.0355	0.2943	0.5661
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0057	0.0196	0.0377
Onchocerca volvulus		0.0057	0.0196	0.0219
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/Met protein kinase	0.0245	0.1928	0.2151
Trichomonas vaginalis	synaptic glycoprotein sc2, putative	0.0067	0.0287	0.0713
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0245	0.1928	0.3708
Echinococcus granulosus	expressed conserved protein	0.0355	0.2943	0.5661
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Entamoeba histolytica	serine/threonine kinase, putative	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0245	0.1928	0.3708
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0355	0.2943	0.5661
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0057	0.0196	0.0311
Schistosoma mansoni	growth factor receptor-bound protein	0.0355	0.2943	0.5661
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Loa Loa (eye worm)	TK/ALK protein kinase	0.0245	0.1928	0.2151
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Schistosoma mansoni	tensin-related	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus multilocularis	tyrosine kinase	0.0248	0.1962	0.3775
Loa Loa (eye worm)	hypothetical protein	0.0536	0.4611	0.5144
Entamoeba histolytica	tyrosin kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0248	0.1962	0.2189
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0245	0.1928	0.3708
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0245	0.1928	0.3708
Brugia malayi	Protein kinase domain containing protein	0.0245	0.1928	0.3057
Schistosoma mansoni	tyrosine kinase	0.0245	0.1928	0.3708
Onchocerca volvulus		0.0245	0.1928	0.2151
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0245	0.1928	0.3057
Echinococcus granulosus	glutamate NMDA receptor subunit	0.0074	0.0357	0.0688
Schistosoma mansoni	retinoic acid receptor RXR	0.0057	0.0196	0.0377
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0355	0.2943	0.3283
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0245	0.1928	0.3708
Entamoeba histolytica	tyrosine kinase, putative	0.0245	0.1928	0.3342
Schistosoma mansoni	synaptic glycoprotein sc2 related	0.0067	0.0287	0.0553
Onchocerca volvulus	Epoxide hydrolase 1 homolog	0.1008	0.8964	1
Brugia malayi	SH2 domain containing protein	0.0355	0.2943	0.4667
Schistosoma mansoni	RAR-like nuclear receptor	0.0057	0.0196	0.0377
Brugia malayi	nuclear receptor NHR-88	0.0057	0.0196	0.0311
Echinococcus multilocularis	activin receptor type	0.0245	0.1928	0.3708
Loa Loa (eye worm)	TK protein kinase	0.0599	0.5196	0.5796
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0057	0.0196	0.0377
Trypanosoma cruzi	protein kinase, putative	0.0245	0.1928	0.3057
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0355	0.2943	0.3283
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus multilocularis	SH2 motif	0.0355	0.2943	0.5661
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0245	0.1928	0.4781
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0599	0.5196	0.9996
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0057	0.0196	0.0377
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0057	0.0196	0.0311
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	hypothetical protein	0.0368	0.3064	0.3418
Entamoeba histolytica	protein kinase, putative	0.0245	0.1928	0.3342
Trichomonas vaginalis	protein kinase atn1, putative	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK protein kinase	0.0245	0.1928	0.2151
Schistosoma mansoni	protein kinase	0.0245	0.1928	0.3708
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Echinococcus granulosus	tensin	0.0355	0.2943	0.5661
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0245	0.1928	0.4781
Echinococcus granulosus	SH2 motif	0.0355	0.2943	0.5661
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0245	0.1928	0.2151
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0599	0.5196	0.9996
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0355	0.2943	0.5661
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0057	0.0196	0.0311
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Schistosoma mansoni	hypothetical protein	0.0245	0.1928	0.3708
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0057	0.0196	0.0377
Schistosoma mansoni	SH2A	0.0355	0.2943	0.5661
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0599	0.5196	0.9996
Entamoeba histolytica	hypothetical protein	0.0245	0.1928	0.3342
Echinococcus multilocularis	insulin receptor	0.0245	0.1928	0.3708
Echinococcus multilocularis	tyrosine protein kinase	0.0245	0.1928	0.3708
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0245	0.1928	0.4781
Loa Loa (eye worm)	TK/FER protein kinase	0.0599	0.5196	0.5796
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0245	0.1928	0.3708
Trichomonas vaginalis	conserved hypothetical protein	0.0245	0.1928	0.4781
Mycobacterium ulcerans	hypothetical protein	0.0473	0.4032	0.4032
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0057	0.0196	0.0377
Trichomonas vaginalis	3-oxo-5-alpha-steroid 4-dehydrogenase, putative	0.0473	0.4032	1
Echinococcus granulosus	kinase suppressor of Ras 1	0.0245	0.1928	0.3708
Plasmodium vivax	protein kinase, putative	0.0245	0.1928	1
Trichomonas vaginalis	TKL family protein kinase	0.0245	0.1928	0.4781
Loa Loa (eye worm)	SRC-1	0.0599	0.5196	0.5796
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0599	0.5196	0.9996
Loa Loa (eye worm)	hypothetical protein	0.0355	0.2943	0.3283
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0042	0.0059	0.0113
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0057	0.0196	0.0377
Loa Loa (eye worm)	hypothetical protein	0.0245	0.1928	0.2151
Entamoeba histolytica	tyrosin kinase, putative	0.0245	0.1928	0.3342

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (binding)	= 91 %	Binding affinity to mouse GAT1 expressed in HEK293 cells membranes assessed as remaining [2H10]NO711 binding level at 10 uM using LC-ESI-MS/MS analysis by [2H10]NO711 binding inhibition assay	ChEMBL.	23336362

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2315977

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 1740083