Detailed information for compound 1740897

Basic information

Technical information
  • TDR Targets ID: 1740897
  • Name: 2-(4-phenylphenyl)benzaldehyde
  • MW: 258.314 | Formula: C19H14O
  • H donors: 0 H acceptors: 1 LogP: 4.64 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=Cc1ccccc1c1ccc(cc1)c1ccccc1
  • InChi: 1S/C19H14O/c20-14-18-8-4-5-9-19(18)17-12-10-16(11-13-17)15-6-2-1-3-7-15/h1-14H
  • InChiKey: GSBDCKILABWJNG-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi cytokine inducible SH2-containing protein 5 0.0355 0.2943 0.4667
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Onchocerca volvulus 0.0355 0.2943 0.3283
Plasmodium falciparum protein kinase, putative 0.0245 0.1928 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0245 0.1928 1
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0067 0.0287 0.0553
Echinococcus multilocularis ephrin type A receptor 4 A 0.0245 0.1928 0.3708
Leishmania major C-8 sterol isomerase-like protein 0.072 0.6305 1
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0245 0.1928 0.3342
Giardia lamblia Kinase, NEK 0.0245 0.193 1
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0059 0.0093
Echinococcus granulosus c src tyrosine kinase 0.0599 0.5196 0.9996
Echinococcus granulosus ankyrin repeat protein 0.0162 0.1167 0.2245
Schistosoma mansoni nck2/grb4 0.0355 0.2943 0.5661
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0245 0.1928 0.3708
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0355 0.2943 0.5661
Echinococcus granulosus tyrosine protein kinase shark 0.06 0.5198 1
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0245 0.1928 0.3708
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Loa Loa (eye worm) TK/ACK protein kinase 0.0245 0.1928 0.2151
Echinococcus granulosus tyrosine kinase 0.0599 0.5196 0.9996
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0473 0.4032 1
Brugia malayi SH2 domain containing protein 0.0599 0.5196 0.8241
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0599 0.5196 0.9996
Plasmodium vivax polyprenol reductase, putative 0.0067 0.0287 0.1491
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0355 0.2943 0.5661
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0067 0.0287 0.0713
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.0473 0.4032 0.6395
Echinococcus granulosus growth factor receptor bound protein 2 0.0355 0.2943 0.5661
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Echinococcus granulosus integrin linked protein kinase 0.0245 0.1928 0.3708
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0057 0.0196 0.0377
Loa Loa (eye worm) steroid hormone receptor 0.0057 0.0196 0.0219
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Echinococcus granulosus N chimaerin 0.0355 0.2943 0.5661
Brugia malayi SRC-1 0.0599 0.5196 0.8241
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0042 0.0059 0.0113
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Schistosoma mansoni GTPase activating protein 0.0355 0.2943 0.5661
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0248 0.1962 0.2189
Schistosoma mansoni thyroid hormone receptor 0.0057 0.0196 0.0377
Schistosoma mansoni tyrosine kinase 0.0599 0.5196 0.9996
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0057 0.0196 0.0377
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Schistosoma mansoni protein kinase 0.0248 0.1962 0.3775
Onchocerca volvulus 0.0067 0.0287 0.0321
Brugia malayi hypothetical protein 0.0245 0.1928 0.3057
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi Protein kinase domain containing protein 0.0599 0.5196 0.8241
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0057 0.0196 0.0219
Echinococcus granulosus fibroblast growth factor receptor 4 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Echinococcus granulosus activated cdc42 kinase 1 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi tRNA modification GTPase TrmE family protein 0.0355 0.2943 0.4667
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0057 0.0196 0.0377
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Schistosoma mansoni hypothetical protein 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0066
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.1928 0.3057
Schistosoma mansoni tyrosine kinase 0.0599 0.5196 0.9996
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0059 0.0093
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0473 0.4032 0.6395
Entamoeba histolytica receptor protein kinase, putative 0.0245 0.1928 0.3342
Onchocerca volvulus 0.0599 0.5196 0.5796
Echinococcus multilocularis receptor type guanylyl cyclase 0.0248 0.1962 0.3775
Echinococcus granulosus receptor type guanylyl cyclase 0.0248 0.1962 0.3775
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0355 0.2943 0.3283
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Echinococcus granulosus natriuretic peptide receptor 1 0.0245 0.1928 0.3708
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0355 0.2943 0.3283
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0057 0.0196 0.0377
Brugia malayi steroid hormone receptor 0.0057 0.0196 0.0311
Loa Loa (eye worm) TK/EGFR protein kinase 0.0245 0.1928 0.2151
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Echinococcus granulosus tyrosine protein kinase Srms 0.0599 0.5196 0.9996
Trypanosoma cruzi protein kinase, putative 0.0245 0.1928 0.3057
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus multilocularis heat shock protein 70 0.0245 0.1928 0.3708
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Brugia malayi Variant SH3 domain containing protein 0.0355 0.2943 0.4667
Brugia malayi Guanylyl cyclase protein 23 0.0248 0.1962 0.3112
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Entamoeba histolytica cysteine surface protein, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Schistosoma mansoni tyrosine kinase 0.0248 0.1962 0.3775
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0067 0.0287 0.0713
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus multilocularis transient receptor potential cation channel 0.0167 0.1215 0.2337
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0042 0.0059 0.0113
Loa Loa (eye worm) TK/EPH protein kinase 0.0245 0.1928 0.2151
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0599 0.5196 0.9996
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TK family protein kinase 0.0245 0.1928 0.4781
Echinococcus multilocularis SH2 motif 0.0355 0.2943 0.5661
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0355 0.2943 0.5661
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Onchocerca volvulus 0.0245 0.1928 0.2151
Echinococcus granulosus insulin receptor 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0599 0.5196 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0599 0.5196 0.9996
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0057 0.0196 0.0219
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus granulosus SH2 domain containing protein 7 0.0355 0.2943 0.5661
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Echinococcus granulosus retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0245 0.1928 0.4781
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis protein kinase 0.0245 0.1928 0.3708
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0599 0.5196 0.9996
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0355 0.2943 0.541
Echinococcus multilocularis synaptic glycoprotein sc2 0.0067 0.0287 0.0553
Echinococcus granulosus tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus granulosus synaptic glycoprotein sc2 0.0067 0.0287 0.0553
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0057 0.0196 0.0311
Echinococcus granulosus FTZ F1 alpha 0.0057 0.0196 0.0377
Trypanosoma brucei Flagellum attachment zone protein 20 0.0245 0.1928 0.3057
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0473 0.4032 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0245 0.1928 0.3708
Schistosoma mansoni glutamate receptor NMDA 0.0074 0.0357 0.0688
Echinococcus granulosus tyrosine protein kinase Lyn 0.0599 0.5196 0.9996
Echinococcus multilocularis N chimaerin 0.0355 0.2943 0.5661
Schistosoma mansoni signal transduction protein lnk-related 0.0355 0.2943 0.5661
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Brugia malayi hypothetical protein 0.0042 0.0059 0.0093
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Giardia lamblia Protein 21.1 0.0245 0.1928 0.9986
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0245 0.1928 0.4781
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0355 0.2943 0.3283
Toxoplasma gondii protein kinase domain-containing protein 0.0245 0.1928 0.4781
Plasmodium falciparum tyrosine kinase-like protein 0.0245 0.1928 1
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tensin-related 0.0355 0.2943 0.5661
Onchocerca volvulus 0.0599 0.5196 0.5796
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase, putative 0.0355 0.2943 0.541
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Echinococcus granulosus tyrosine kinase 0.0599 0.5196 0.9996
Leishmania major protein kinase, putative 0.0245 0.1928 0.3057
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0057 0.0196 0.0219
Echinococcus multilocularis raf serine:threonine protein kinase 0.0245 0.1928 0.3708
Entamoeba histolytica serine/threonine kinase, putative 0.0245 0.1928 0.3342
Onchocerca volvulus Bile acid receptor homolog 0.0536 0.4611 0.5144
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.0196 0.0311
Brugia malayi Protein kinase domain containing protein 0.0599 0.5196 0.8241
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0245 0.1928 0.3057
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0057 0.0196 0.0377
Echinococcus granulosus tyrosine kinase 0.0248 0.1962 0.3775
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Echinococcus multilocularis tensin 0.0355 0.2943 0.5661
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.0473 0.4032 0.6395
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0599 0.5196 0.9996
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0473 0.4032 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0245 0.1928 0.3708
Trichomonas vaginalis CAMK family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tensin 0.0355 0.2943 0.5661
Echinococcus multilocularis FL cytokine receptor 0.0245 0.1928 0.3708
Echinococcus multilocularis protein KINase family member (kin 25) 0.0245 0.1928 0.3708
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Echinococcus multilocularis tyrosine protein kinase csk 0.0245 0.1928 0.3708
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0088 0.0169
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0074 0.0357 0.0688
Entamoeba histolytica ankyrin repeat protein 0.0245 0.1928 0.3342
Brugia malayi Raf kinase 0.0245 0.1928 0.3057
Brugia malayi STAT protein, DNA binding domain containing protein 0.0355 0.2943 0.4667
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0245 0.1928 0.3057
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0245 0.1928 0.2151
Trypanosoma brucei Pseudokinase, putative 0.0245 0.1928 0.3057
Loa Loa (eye worm) serine/threonine protein kinase 0.0245 0.1928 0.2151
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus granulosus tyrosine protein kinase Src42A 0.0355 0.2943 0.5661
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0245 0.1928 0.2151
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0162 0.1167 0.2245
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Schistosoma mansoni tyrosine kinase 0.0599 0.5196 0.9996
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi ephrin receptor 1 precursor 0.0245 0.1928 0.3057
Onchocerca volvulus 0.0355 0.2943 0.3283
Schistosoma mansoni nuclear hormone receptor 0.0057 0.0196 0.0377
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0245 0.1928 0.2151
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Brugia malayi hydrolase, alpha/beta fold family protein 0.0501 0.4286 0.6798
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0067 0.0287 0.0713
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Schistosoma mansoni serine/threonine RGC 0.0245 0.1928 0.3708
Leishmania major protein kinase, putative 0.0245 0.1928 0.3057
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Entamoeba histolytica serine/threonine kinase, putative 0.0245 0.1928 0.3342
Onchocerca volvulus 0.0245 0.1928 0.2151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0245 0.1928 0.3057
Loa Loa (eye worm) TK/DDR protein kinase 0.0245 0.1928 0.2151
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis tensin 0.0355 0.2943 0.5661
Echinococcus multilocularis activated cdc42 kinase 1 0.0245 0.1928 0.3708
Plasmodium falciparum protein kinase, putative 0.0245 0.1928 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) RGC/RGC protein kinase 0.0248 0.1962 0.2189
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0355 0.2943 0.5661
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) RGC/RGC protein kinase 0.0245 0.1928 0.2151
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0599 0.5196 0.9996
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0088 0.0169
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0057 0.0196 0.0311
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0245 0.1928 0.3057
Schistosoma mansoni protein kinase 0.0245 0.193 0.3713
Plasmodium vivax tyrosine kinase-like protein, putative 0.0245 0.1928 1
Toxoplasma gondii STE kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica ankyrin repeat protein 0.0245 0.1928 0.3342
Echinococcus multilocularis integrin linked protein kinase 0.0245 0.1928 0.3708
Brugia malayi Nuclear hormone receptor-like 1 0.0057 0.0196 0.0311
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0599 0.5196 0.9996
Echinococcus granulosus ephrin type A receptor 4 A 0.0245 0.1928 0.3708
Brugia malayi hypothetical protein 0.0042 0.0059 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0057 0.0196 0.0311
Echinococcus multilocularis ankyrin repeat protein 0.0162 0.1167 0.2245
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Echinococcus multilocularis protein tyrosine kinase 0.0245 0.1928 0.3708
Brugia malayi Furin-like cysteine rich region family protein 0.0245 0.1928 0.3057
Echinococcus multilocularis epidermal growth factor receptor 0.0245 0.1928 0.3708
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0245 0.1928 0.2151
Schistosoma mansoni ephrin receptor 0.0245 0.1928 0.3708
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0066
Echinococcus multilocularis tyrosine protein kinase Abl 0.0599 0.5196 0.9996
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Brugia malayi hypothetical protein 0.0599 0.5196 0.8241
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0066
Echinococcus multilocularis tyrosine protein kinase csk 0.0245 0.1928 0.3708
Echinococcus multilocularis SHC transforming protein 3 0.0355 0.2943 0.5661
Schistosoma mansoni suppressor of cytokine signaling 0.0355 0.2943 0.5661
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Brugia malayi Tyrosine-protein kinase PR2 0.0245 0.1928 0.3057
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0355 0.2943 0.5661
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus granulosus tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Schistosoma mansoni steroid hormone receptor ad4bp 0.0057 0.0196 0.0377
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0057 0.0196 0.0377
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Brugia malayi Receptor family ligand binding region containing protein 0.0248 0.1962 0.3112
Loa Loa (eye worm) SH2 domain-containing protein 0.0355 0.2943 0.3283
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0287 0.0713
Echinococcus multilocularis SH2 domain containing protein 7 0.0355 0.2943 0.5661
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0088 0.0169
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0245 0.1928 0.3708
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.1754 0.1754
Loa Loa (eye worm) TK/CSK protein kinase 0.0245 0.1928 0.2151
Echinococcus granulosus raf serine:threonine protein kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0245 0.1928 0.3708
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0057 0.0196 0.0219
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0057 0.0196 0.0377
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0245 0.1928 0.2151
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis tyrosine protein kinase shark 0.06 0.5198 1
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Plasmodium falciparum protein kinase, putative 0.0245 0.1928 1
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica SH2 domain containing protein 0.0355 0.2943 0.541
Giardia lamblia Kinase, NEK 0.0245 0.1928 0.9986
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0245 0.1928 0.3057
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi Tyrosine-protein kinase abl-1 0.0599 0.5196 0.8241
Echinococcus granulosus SHC transforming protein 3 0.0355 0.2943 0.5661
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus multilocularis SH2 motif 0.0355 0.2943 0.5661
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0144 0.016
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Loa Loa (eye worm) hypothetical protein 0.0067 0.0287 0.0321
Brugia malayi RhoGAP domain containing protein 0.0355 0.2943 0.4667
Schistosoma mansoni protein kinase 0.0245 0.193 0.3713
Echinococcus multilocularis transfer RNA-Thr 0.0245 0.1928 0.3708
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Echinococcus granulosus activated cdc42 kinase 1 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine protein kinase csk 0.0245 0.1928 0.3708
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Schistosoma mansoni coup transcription factor 0.0057 0.0196 0.0377
Toxoplasma gondii protein kinase 0.0245 0.1928 0.4781
Echinococcus multilocularis tyrosine protein kinase csk 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0196 0.0377
Echinococcus multilocularis thyroid hormone receptor alpha 0.0057 0.0196 0.0377
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Entamoeba histolytica serine/threonine kinase, putative 0.0245 0.1928 0.3342
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0067 0.0287 0.0456
Echinococcus multilocularis tyrosine protein kinase HCK 0.0245 0.1928 0.3708
Loa Loa (eye worm) hypothetical protein 0.0473 0.4032 0.4498
Loa Loa (eye worm) STAT protein 0.0355 0.2943 0.3283
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0057 0.0196 0.0377
Brugia malayi protein-tyrosine kinase 0.0599 0.5196 0.8241
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0057 0.0196 0.0311
Mycobacterium ulcerans short chain dehydrogenase 0.1121 1 1
Brugia malayi Tensin 0.0355 0.2943 0.4667
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0245 0.1928 0.2151
Brugia malayi nuclear receptor RXR 0.0042 0.0059 0.0093
Trypanosoma cruzi C-8 sterol isomerase, putative 0.072 0.6305 1
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Loa Loa (eye worm) TK/FAK protein kinase 0.0245 0.1928 0.2151
Brugia malayi hypothetical protein 0.0355 0.2943 0.4667
Mycobacterium leprae conserved hypothetical protein 0.0035 0 0.5
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0245 0.1928 0.2151
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0245 0.1928 0.3708
Echinococcus multilocularis epidermal growth factor receptor 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Brugia malayi SH2 domain containing protein 0.0599 0.5196 0.8241
Entamoeba histolytica serine/threonine kinase, putative 0.0245 0.1928 0.3342
Schistosoma mansoni adapter molecule crk 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Trypanosoma brucei protein kinase, putative 0.0245 0.1928 0.3057
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.072 0.6305 0.7034
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis tyrosine protein kinase Blk 0.0599 0.5196 0.9996
Trypanosoma brucei C-8 sterol isomerase, putative 0.072 0.6305 1
Brugia malayi C-terminal src kinase protein 1 0.0245 0.1928 0.3057
Brugia malayi photoreceptor-specific nuclear receptor 0.0057 0.0196 0.0311
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0355 0.2943 0.5661
Schistosoma mansoni tyrosine kinase 0.0599 0.5196 0.9996
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0088 0.0169
Loa Loa (eye worm) SH2 domain-containing protein 0.0355 0.2943 0.3283
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0599 0.5196 0.9996
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Schistosoma mansoni SH2A 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0196 0.0377
Schistosoma mansoni hypothetical protein 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Trichomonas vaginalis protein tyrosine kinase, putative 0.0245 0.1928 0.4781
Echinococcus multilocularis insulin receptor 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine protein kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) protein kinase domain-containing protein 0.0245 0.1928 0.2151
Echinococcus granulosus SH2 domain containing adapter protein F 0.0355 0.2943 0.5661
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0599 0.5196 0.9996
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.0196 0.0311
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Plasmodium vivax protein kinase, putative 0.0245 0.1928 1
Entamoeba histolytica tyrosin kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0057 0.0196 0.0377
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0042 0.0059 0.0113
Loa Loa (eye worm) SRC-1 0.0599 0.5196 0.5796
Mycobacterium ulcerans hypothetical protein 0.0473 0.4032 0.4032
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0245 0.1928 0.3708
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0473 0.4032 1
Echinococcus granulosus kinase suppressor of Ras 1 0.0245 0.1928 0.3708
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0057 0.0196 0.0377
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0057 0.0196 0.0311
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0245 0.1928 0.4781
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0057 0.0196 0.0377
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0599 0.5196 0.9996
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Echinococcus granulosus SH2 motif 0.0355 0.2943 0.5661
Echinococcus granulosus tensin 0.0355 0.2943 0.5661
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0245 0.1928 0.4781
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0368 0.3064 0.3418
Trichomonas vaginalis protein kinase atn1, putative 0.0245 0.1928 0.4781
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.1008 0.8964 1
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0067 0.0287 0.0553
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis tyrosine protein kinase pr2 0.0245 0.1928 0.3708
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0355 0.2943 0.3283
Schistosoma mansoni retinoic acid receptor RXR 0.0057 0.0196 0.0377
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0245 0.1928 0.3057
Echinococcus granulosus glutamate NMDA receptor subunit 0.0074 0.0357 0.0688
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Onchocerca volvulus 0.0245 0.1928 0.2151
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0355 0.2943 0.3283
Trypanosoma cruzi protein kinase, putative 0.0245 0.1928 0.3057
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Echinococcus multilocularis SH2 motif 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni RAR-like nuclear receptor 0.0057 0.0196 0.0377
Brugia malayi nuclear receptor NHR-88 0.0057 0.0196 0.0311
Loa Loa (eye worm) TK protein kinase 0.0599 0.5196 0.5796
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0057 0.0196 0.0377
Echinococcus multilocularis activin receptor type 0.0245 0.1928 0.3708
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.0196 0.0311
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0355 0.2943 0.5661
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/ALK protein kinase 0.0245 0.1928 0.2151
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Schistosoma mansoni growth factor receptor-bound protein 0.0355 0.2943 0.5661
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Echinococcus granulosus retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0245 0.1928 0.3708
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) RGC/RGC protein kinase 0.0248 0.1962 0.2189
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine kinase 0.0248 0.1962 0.3775
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tensin-related 0.0355 0.2943 0.5661
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Entamoeba histolytica tyrosin kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0536 0.4611 0.5144
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0245 0.1928 0.4781
Schistosoma mansoni vav2 0.0355 0.2943 0.5661
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0057 0.0196 0.0377
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.0473 0.4032 0.6395
Entamoeba histolytica serine/threonine kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Brugia malayi Protein kinase domain containing protein 0.0599 0.5196 0.8241
Brugia malayi bone morphogenetic protein type 1 receptor 0.0245 0.1928 0.3057
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0245 0.1928 0.3708
Echinococcus granulosus expressed conserved protein 0.0355 0.2943 0.5661
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0067 0.0287 0.0713
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Loa Loa (eye worm) TK/Met protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica serine/threonine kinase, putative 0.0245 0.1928 0.3342
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus granulosus NCK adaptor protein 0.0355 0.2943 0.5661
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0245 0.1928 0.3708
Loa Loa (eye worm) TK/ROR protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Onchocerca volvulus 0.0057 0.0196 0.0219
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0057 0.0196 0.0377
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Onchocerca volvulus 0.0245 0.1928 0.2151
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Schistosoma mansoni thyroid hormone receptor 0.0057 0.0196 0.0377
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus granulosus suppressor of cytokine signaling 7 0.0355 0.2943 0.5661
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Onchocerca volvulus 0.0599 0.5196 0.5796
Echinococcus granulosus protein kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis FTZ F1 alpha 0.0057 0.0196 0.0377
Schistosoma mansoni tyrosine kinase 0.06 0.5198 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0287 0.0321
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0067 0.0287 0.0456
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0245 0.1928 0.3708
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0067 0.0287 0.1491
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0245 0.1928 0.3057
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0355 0.2943 0.5661
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0245 0.1928 0.3708
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Brugia malayi Protein kinase domain containing protein 0.0599 0.5196 0.8241
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0057 0.0196 0.0377
Onchocerca volvulus 0.0245 0.1928 0.2151
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus granulosus signal transduction protein lnk realted 0.0355 0.2943 0.5661
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0355 0.2943 0.3283
Loa Loa (eye worm) TK/ABL protein kinase 0.0599 0.5196 0.5796
Loa Loa (eye worm) hypothetical protein 0.0051 0.0144 0.016
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0245 0.1928 0.3708
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Echinococcus granulosus tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Onchocerca volvulus Protein ultraspiracle homolog 0.0057 0.0196 0.0219
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0088 0.014
Brugia malayi integrin-linked kinase 0.0245 0.1928 0.3057
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0245 0.1928 0.3057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0057 0.0196 0.0219
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0144 0.0228
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0144 0.0228
Echinococcus multilocularis ecdysone induced protein 78C 0.0057 0.0196 0.0377
Brugia malayi Synaptic glycoprotein SC2 0.0067 0.0287 0.0456
Entamoeba histolytica tyrosin kinase, putative 0.0245 0.1928 0.3342
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Onchocerca volvulus Tyrosine kinase homolog 0.0245 0.1928 0.2151
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0057 0.0196 0.0311
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Onchocerca volvulus 0.0599 0.5196 0.5796
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0473 0.4032 0.6395
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Mycobacterium leprae Probable lipase LipE 0.0035 0 0.5
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0042 0.0059 0.0066
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Loa Loa (eye worm) RGC/RGC protein kinase 0.0248 0.1962 0.2189
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0057 0.0196 0.0311
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Loa Loa (eye worm) hypothetical protein 0.0057 0.0196 0.0219
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Echinococcus granulosus SH2 motif 0.0355 0.2943 0.5661
Brugia malayi Sex muscle abnormal protein 5 0.0355 0.2943 0.4667
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0088 0.0169
Brugia malayi hypothetical protein 0.0245 0.1928 0.3057
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0599 0.5196 0.9996
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Onchocerca volvulus 0.0355 0.2943 0.3283
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Loa Loa (eye worm) hypothetical protein 0.0599 0.5196 0.5796
Echinococcus granulosus tyrosine protein kinase ABL1 0.0599 0.5196 0.9996
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Echinococcus multilocularis c src tyrosine kinase 0.0599 0.5196 0.9996
Onchocerca volvulus 0.0245 0.1928 0.2151
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0066
Echinococcus granulosus tyrosine protein kinase Blk 0.0599 0.5196 0.9996
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0088 0.0098
Onchocerca volvulus 0.0355 0.2943 0.3283
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0355 0.2943 0.5661
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0057 0.0196 0.0219
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Brugia malayi Variant SH3 domain containing protein 0.0355 0.2943 0.4667
Onchocerca volvulus 0.0599 0.5196 0.5796
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Schistosoma mansoni suppressor of cytokine signaling 0.0355 0.2943 0.5661
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0245 0.1928 0.2151
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0355 0.2943 0.5661
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0599 0.5196 0.9996
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0067 0.0287 0.0553
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0067 0.0287 0.0553
Echinococcus granulosus epidermal growth factor receptor 0.0245 0.1928 0.3708
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0067 0.0287 0.0713
Echinococcus multilocularis 0.0355 0.2943 0.5661
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0057 0.0196 0.0377
Loa Loa (eye worm) hydrolase 0.1008 0.8964 1
Schistosoma mansoni hypothetical protein 0.0355 0.2943 0.5661
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0245 0.1928 0.3708
Echinococcus granulosus epidermal growth factor receptor 0.0245 0.1928 0.3708
Onchocerca volvulus 0.0599 0.5196 0.5796
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0067 0.0287 0.0713
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus granulosus activin receptor type 0.0245 0.1928 0.3708
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0355 0.2943 0.5661
Schistosoma mansoni protein tyrosine kinase 0.0245 0.1928 0.3708
Schistosoma mansoni ephrin receptor 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis signal transduction protein lnk realted 0.0355 0.2943 0.5661
Echinococcus granulosus tyrosine protein kinase Src42A 0.0599 0.5196 0.9996
Schistosoma mansoni tensin 0.0355 0.2943 0.5661
Echinococcus granulosus suppressor of cytokine signaling 6 0.0355 0.2943 0.5661
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0245 0.1928 0.3057
Echinococcus granulosus tyrosine protein kinase csk 0.0245 0.1928 0.3708
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.1928 0.3708
Echinococcus multilocularis growth factor receptor bound protein 2 0.0355 0.2943 0.5661
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0057 0.0196 0.0311
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0599 0.5196 0.9996
Loa Loa (eye worm) hypothetical protein 0.0248 0.1962 0.2189
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0245 0.1928 0.3708
Loa Loa (eye worm) TK protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) hypothetical protein 0.0042 0.0059 0.0066
Loa Loa (eye worm) hypothetical protein 0.0245 0.1928 0.2151
Trichomonas vaginalis STE family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica receptor protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus granulosus tyrosine protein kinase 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0057 0.0196 0.0219
Entamoeba histolytica steroid 5-alpha reductase, putative 0.0473 0.4032 0.7629
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0059 0.0113
Entamoeba histolytica hypothetical protein 0.0245 0.1928 0.3342
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0245 0.1928 0.3057
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0057 0.0196 0.0377
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0355 0.2943 0.5661
Onchocerca volvulus 0.0248 0.1962 0.2189
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0245 0.1928 0.3708
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0245 0.1928 0.3708
Trichomonas vaginalis AGC family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Onchocerca volvulus 0.0245 0.1928 0.2151
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0057 0.0196 0.0311
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus multilocularis NCK adaptor protein 0.0355 0.2943 0.5661
Schistosoma mansoni shc transforming protein 0.0355 0.2943 0.5661
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0355 0.2943 0.5661
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0599 0.5196 0.8241
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tensin 0.0355 0.2943 0.5661
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0245 0.1928 0.3708
Echinococcus granulosus tyrosine protein kinase csk 0.0245 0.1928 0.3708
Echinococcus granulosus transient receptor potential cation channel 0.0167 0.1212 0.2332
Schistosoma mansoni tyrosine kinase 0.0599 0.5196 0.9996
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0355 0.2943 0.5661
Loa Loa (eye worm) TK/RYK protein kinase 0.0245 0.1928 0.2151
Entamoeba histolytica hypothetical protein, conserved 0.0245 0.1928 0.3342
Leishmania major hypothetical protein, conserved 0.0245 0.1928 0.3057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0057 0.0196 0.0219
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0599 0.5196 0.9996
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0245 0.1928 0.3342
Trichomonas vaginalis conserved hypothetical protein 0.0245 0.1928 0.4781
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0599 0.5196 0.9996
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Onchocerca volvulus 0.0355 0.2943 0.3283
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0355 0.2943 0.5661
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0088 0.0169
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0245 0.1928 0.4781
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0355 0.2943 0.4667
Loa Loa (eye worm) hypothetical protein 0.0355 0.2943 0.3283
Echinococcus multilocularis tyrosine kinase 0.0599 0.5196 0.9996
Schistosoma mansoni growth factor receptor-bound protein 0.0355 0.2943 0.5661
Entamoeba histolytica tyrosin kinase, putative 0.0245 0.1928 0.3342
Echinococcus multilocularis protein kinase 0.0245 0.1928 0.3708
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Echinococcus granulosus tyrosine protein kinase csk 0.0245 0.1928 0.3708
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0245 0.1928 0.2151
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0088 0.0169
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0245 0.1928 0.3708
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Echinococcus granulosus hypothetical protein 0.0355 0.2943 0.5661
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) SH2 domain-containing protein 0.0355 0.2943 0.3283
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi Steroid receptor seven-up type 2 0.0057 0.0196 0.0311
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0355 0.2943 0.3283
Onchocerca volvulus 0.0355 0.2943 0.3283
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Brugia malayi ecdysteroid receptor 0.0536 0.4611 0.7313
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0245 0.1928 0.3057
Echinococcus multilocularis kinase suppressor of Ras 1 0.0245 0.1928 0.3708
Echinococcus multilocularis natriuretic peptide receptor 1 0.0245 0.1928 0.3708
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0287 0.0713
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0355 0.2943 0.3283
Schistosoma mansoni tyrosine protein kinase 0.0245 0.1928 0.3708
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0057 0.0196 0.0311
Echinococcus granulosus tyrosine protein kinase Src64B 0.0599 0.5196 0.9996
Echinococcus granulosus tyrosine protein kinase HCK 0.0245 0.1928 0.3708
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Brugia malayi Variant SH3 domain containing protein 0.0355 0.2943 0.4667
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Onchocerca volvulus 0.0245 0.1928 0.2151
Brugia malayi Variant SH3 domain containing protein 0.0355 0.2943 0.4667
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Echinococcus multilocularis tyrosine protein kinase Srms 0.0599 0.5196 0.9996
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0245 0.1928 0.3342
Brugia malayi SH2 domain containing protein 0.0355 0.2943 0.4667
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni protein kinase 0.0245 0.1928 0.3708
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0355 0.2943 0.5661
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica protein kinase, putative 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/INSR protein kinase 0.0245 0.1928 0.2151
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Brugia malayi ERG2 and Sigma1 receptor like protein 0.072 0.6305 1
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tyrosine kinase 0.0245 0.1928 0.3708
Brugia malayi Protein kinase domain containing protein 0.0245 0.1928 0.3057
Entamoeba histolytica protein kinase domain containing protein 0.0245 0.1928 0.3342
Loa Loa (eye worm) TK/FER protein kinase 0.0245 0.1928 0.2151
Echinococcus granulosus ecdysone induced protein 78C 0.0057 0.0196 0.0377
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Schistosoma mansoni tyrosine kinase 0.0248 0.1962 0.3775
Loa Loa (eye worm) TK/FER protein kinase 0.0599 0.5196 0.5796
Plasmodium falciparum tyrosine kinase-like protein 0.0245 0.1928 1
Echinococcus granulosus protein tyrosine kinase 0.0245 0.1928 0.3708
Trichomonas vaginalis TKL family protein kinase 0.0245 0.1928 0.4781
Entamoeba histolytica tyrosine kinase, putative 0.0245 0.1928 0.3342
Brugia malayi nuclear hormone receptor 0.0057 0.0196 0.0311
Giardia lamblia Kinase 0.0245 0.1928 0.9986

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 81 % Binding affinity to mouse GAT1 expressed in HEK293 cells membranes assessed as remaining [2H10]NO711 binding level at 10 uM using LC-ESI-MS/MS analysis by [2H10]NO711 binding inhibition assay ChEMBL. 23336362

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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