Detailed information for compound 1745556

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 956.243 | Formula: C45H81N9O11S
  • H donors: 10 H acceptors: 11 LogP: 2.97 Rotable bonds: 40
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC[C@@H]([C@@H](C(=O)SCCNC(=O)C)NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C[C@H](O)C)CCC(=O)N)CC(C)C)CC(C)C)C)CC(C)C)C
  • InChi: 1S/C45H81N9O11S/c1-14-27(10)38(45(65)66-18-17-47-30(13)56)54-43(63)33(20-24(4)5)50-39(59)29(12)48-44(64)37(26(8)9)53-42(62)34(21-25(6)7)52-41(61)32(19-23(2)3)51-40(60)31(15-16-35(46)57)49-36(58)22-28(11)55/h23-29,31-34,37-38,55H,14-22H2,1-13H3,(H2,46,57)(H,47,56)(H,48,64)(H,49,58)(H,50,59)(H,51,60)(H,52,61)(H,53,62)(H,54,63)/t27-,28+,29-,31-,32-,33+,34+,37-,38-/m0/s1
  • InChiKey: IQXOKJTYQGYROI-XEALQRPBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0366 0.3669 0.362
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Echinococcus granulosus g protein coupled receptor 0.0104 0.086 0.079
Echinococcus multilocularis raf serine:threonine protein kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Echinococcus granulosus protein kinase 0.0366 0.3669 0.362
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi Dopamine receptor protein 2 0.0104 0.086 0.086
Echinococcus multilocularis neuropeptide s receptor 0.0104 0.086 0.079
Brugia malayi G-protein coupled receptor 0.0104 0.086 0.086
Echinococcus granulosus c src tyrosine kinase 0.0926 0.9681 0.9679
Entamoeba histolytica receptor protein kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni biogenic amine (5HT) receptor 0.0104 0.086 0.079
Echinococcus multilocularis tyrosine protein kinase csk 0.0366 0.3669 0.3622
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0203 0.0354
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0366 0.3669 0.362
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Brugia malayi Furin-like cysteine rich region family protein 0.0514 0.5264 0.5266
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0104 0.086 0.079
Echinococcus granulosus geminin 0.0339 0.3378 0.3327
Brugia malayi sulfakinin receptor protein 0.0104 0.086 0.086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0366 0.3669 0.3671
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Schistosoma mansoni neuropeptide F-like receptor 0.0104 0.086 0.079
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.1695 0.1633
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Schistosoma mansoni tyrosine kinase 0.0922 0.9642 0.9644
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076
Echinococcus multilocularis protein KINase family member (kin 25) 0.0366 0.3669 0.3622
Schistosoma mansoni biogenic amine (5HT) receptor 0.0104 0.086 0.079
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0119 0.007
Plasmodium vivax tyrosine kinase-like protein, putative 0.0366 0.3669 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0104 0.086 0.079
Brugia malayi Raf kinase 0.0366 0.3669 0.3671
Schistosoma mansoni hypothetical protein 0.0104 0.086 0.079
Trichomonas vaginalis CAMK family protein kinase 0.0366 0.3669 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Brugia malayi putative neuropeptide receptor 0.0104 0.086 0.086
Loa Loa (eye worm) G-protein coupled receptor 0.0104 0.086 0.086
Echinococcus multilocularis integrin linked protein kinase 0.0366 0.3669 0.3622
Schistosoma mansoni hypothetical protein 0.0052 0.0301 0.0227
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0126 0.1099 0.11
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Brugia malayi Variant SH3 domain containing protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Onchocerca volvulus 0.0104 0.086 0.0892
Plasmodium falciparum protein kinase, putative 0.0366 0.3669 0.9986
Echinococcus granulosus SHC transforming protein 3 0.0557 0.5718 0.5685
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Brugia malayi AKH receptor 0.0104 0.086 0.086
Echinococcus granulosus N chimaerin 0.0557 0.5718 0.5685
Brugia malayi G-protein coupled receptor 0.0104 0.086 0.086
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0366 0.3669 0.3805
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.3669 0.3622
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0104 0.086 0.079
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Onchocerca volvulus 0.0557 0.5718 0.5931
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Onchocerca volvulus 0.0104 0.086 0.0892
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0557 0.5718 0.5688
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Entamoeba histolytica serine/threonine kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Leishmania major basic transcription factor 3a, putative 0.0035 0.0119 0.0323
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0366 0.3669 0.3622
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0557 0.5718 0.5721
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0922 0.9642 0.9644
Loa Loa (eye worm) hypothetical protein 0.0182 0.1695 0.1696
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.086 0.079
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Echinococcus granulosus retinal guanylyl cyclase 2 0.0366 0.3669 0.362
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Onchocerca volvulus 0.0104 0.086 0.0892
Entamoeba histolytica tyrosin kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0366 0.3669 0.362
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0557 0.5718 0.5685
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Brugia malayi follicle stimulating hormone receptor 0.0104 0.086 0.086
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0413 0.4172 0.4127
Echinococcus granulosus orexin receptor type 2 0.0104 0.086 0.079
Schistosoma mansoni opsin-like receptor 0.0104 0.086 0.079
Echinococcus granulosus protein tyrosine kinase 0.0366 0.3669 0.362
Onchocerca volvulus 0.0104 0.086 0.0892
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Echinococcus granulosus tyrosine kinase 0.0952 0.9956 0.9955
Brugia malayi STAT protein, DNA binding domain containing protein 0.0557 0.5718 0.5721
Brugia malayi SH2 domain containing protein 0.0922 0.9642 0.9647
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0104 0.086 0.086
Echinococcus multilocularis tyrosine protein kinase csk 0.0366 0.3669 0.3622
Brugia malayi GnHR receptor homolog 0.0104 0.086 0.086
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Brugia malayi integrin-linked kinase 0.0366 0.3669 0.3671
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0557 0.5718 0.5688
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0104 0.086 0.079
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) SRC-1 0.0955 0.9995 1
Schistosoma mansoni adapter molecule crk 0.056 0.5758 0.5728
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0119 0.007
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.086 0.079
Onchocerca volvulus 0.0366 0.3669 0.3805
Echinococcus granulosus tachykinin peptides receptor 99D 0.0104 0.086 0.079
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0076 0.0076
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0366 0.3669 0.3622
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Echinococcus multilocularis tyrosine protein kinase Srms 0.0952 0.9956 0.996
Brugia malayi Protein kinase domain containing protein 0.0922 0.9642 0.9647
Echinococcus multilocularis NCK adaptor protein 0.056 0.5758 0.5728
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0076 0.0076
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Schistosoma mansoni neuropeptide receptor 0.0104 0.086 0.079
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus G protein coupled receptor 139 0.0104 0.086 0.079
Echinococcus granulosus neuropeptide Y receptor 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0955 0.9995 1
Echinococcus granulosus somatostatin receptor 0.0104 0.086 0.079
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0366 0.3669 0.3622
Brugia malayi ephrin receptor 1 precursor 0.0366 0.3669 0.3671
Echinococcus granulosus hypothetical protein 0.0557 0.5718 0.5685
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0557 0.5718 0.5931
Plasmodium falciparum tyrosine kinase-like protein 0.0366 0.3669 0.9986
Echinococcus multilocularis protein kinase 0.0366 0.3669 0.3622
Onchocerca volvulus 0.0366 0.3669 0.3805
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0031 0.0076 0.5
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Echinococcus granulosus tyrosine protein kinase pr2 0.0366 0.3669 0.362
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0366 0.3674 0.3627
Schistosoma mansoni amine GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0104 0.086 0.079
Loa Loa (eye worm) SH2 domain-containing protein 0.0557 0.5718 0.5721
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0104 0.086 0.079
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0366 0.3669 0.362
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0119 0.007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.3669 0.3671
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0104 0.086 0.086
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Echinococcus multilocularis fmrfamide receptor 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Brugia malayi cytokine inducible SH2-containing protein 5 0.0557 0.5718 0.5721
Treponema pallidum hypothetical protein 0.0284 0.2794 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus mitogen activated protein kinase 11 0.0126 0.1099 0.1031
Onchocerca volvulus 0.0366 0.3669 0.3805
Schistosoma mansoni suppressor of cytokine signaling 0.0557 0.5718 0.5688
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0104 0.086 0.079
Echinococcus multilocularis SH2 domain containing protein 7 0.0557 0.5718 0.5688
Schistosoma mansoni biogenic amine receptor 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni tyrosine kinase 0.0922 0.9642 0.9644
Brugia malayi Guanylyl cyclase protein 23 0.0366 0.3669 0.3671
Loa Loa (eye worm) sex muscle abnormal protein 5 0.056 0.5758 0.5761
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Echinococcus granulosus fibroblast growth factor receptor 4 0.0366 0.3669 0.362
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Giardia lamblia Kinase, NEK 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus granulosus activated cdc42 kinase 1 0.0366 0.3669 0.362
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Echinococcus multilocularis expressed protein 0.0033 0.0102 0.0026
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis tyrosine protein kinase pr2 0.0366 0.3669 0.3622
Schistosoma mansoni neuropeptide f receptor 76f 0.0104 0.086 0.079
Onchocerca volvulus 0.0104 0.086 0.0892
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0366 0.3669 0.362
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0366 0.3669 0.3671
Toxoplasma gondii STE kinase 0.0366 0.3669 0.9986
Brugia malayi hypothetical protein 0.0366 0.3669 0.3671
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) TK/RYK protein kinase 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.1695 0.1696
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Giardia lamblia Kinase 0.0366 0.3669 1
Echinococcus granulosus activated cdc42 kinase 1 0.0366 0.3669 0.362
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Schistosoma mansoni protein kinase 0.0366 0.3674 0.3627
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus serotonin transporter 0.0182 0.1695 0.1632
Echinococcus granulosus tyrosine protein kinase csk 0.0366 0.3669 0.362
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0104 0.086 0.086
Trichomonas vaginalis protein kinase atn1, putative 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0126 0.1099 0.281
Brugia malayi Serotonin receptor 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0126 0.1099 0.2993
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0366 0.3674 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Brugia malayi Tyrosine-protein kinase PR2 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK/Met protein kinase 0.0366 0.3669 0.3671
Echinococcus multilocularis neuropeptides capa receptor 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0104 0.086 0.079
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0557 0.5718 0.5688
Echinococcus granulosus g-protein coupled receptor 0.0104 0.086 0.079
Echinococcus multilocularis protein kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Onchocerca volvulus 0.0557 0.5718 0.5931
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0119 0.0119
Onchocerca volvulus 0.0104 0.086 0.0892
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) TK/EPH protein kinase 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0955 0.9995 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Onchocerca volvulus 0.0366 0.3669 0.3805
Echinococcus multilocularis tensin 0.0557 0.5718 0.5688
Schistosoma mansoni tyrosine protein kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Echinococcus multilocularis SHC transforming protein 3 0.0557 0.5718 0.5688
Brugia malayi neuropeptide F receptor 0.0104 0.086 0.086
Plasmodium falciparum tyrosine kinase-like protein 0.0366 0.3669 0.9986
Leishmania major protein kinase, putative 0.0366 0.3669 0.9987
Echinococcus granulosus ephrin type A receptor 4 A 0.0366 0.3669 0.362
Echinococcus multilocularis protein tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni tyrosine kinase 0.0079 0.0598 0.0526
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Echinococcus multilocularis g protein coupled receptor 0.0104 0.086 0.079
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0557 0.5718 0.5721
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0955 0.9995 0.9995
Schistosoma mansoni amine GPCR 0.0104 0.086 0.079
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi Dopamine receptor protein 1 0.0104 0.086 0.086
Echinococcus multilocularis g protein coupled receptor 0.0104 0.086 0.079
Echinococcus multilocularis FL cytokine receptor 0.0366 0.3669 0.3622
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0366 0.3669 0.3671
Trypanosoma brucei Flagellum attachment zone protein 20 0.0366 0.3669 0.9986
Echinococcus granulosus tyrosine protein kinase Src64B 0.0955 0.9995 0.9995
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0104 0.086 0.079
Echinococcus granulosus expressed conserved protein 0.0557 0.5718 0.5685
Onchocerca volvulus Tyrosine kinase homolog 0.0366 0.3669 0.3805
Echinococcus granulosus serotonin receptor 0.0104 0.086 0.079
Echinococcus granulosus signal transduction protein lnk realted 0.0557 0.5718 0.5685
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0557 0.5718 0.5688
Echinococcus granulosus neuropeptide FF receptor 2 0.0104 0.086 0.079
Echinococcus multilocularis kinase suppressor of Ras 1 0.0366 0.3669 0.3622
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis conserved hypothetical protein 0.0692 0.7167 0.7149
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0366 0.3669 0.3622
Toxoplasma gondii protein kinase domain-containing protein 0.0366 0.3669 0.9986
Echinococcus granulosus tyrosine protein kinase 0.0366 0.3669 0.362
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0955 0.9995 0.9995
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni protein kinase 0.0366 0.3674 0.3627
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Echinococcus multilocularis heat shock protein 70 0.0366 0.3669 0.3622
Brugia malayi putative neuropeptide receptor NPR1 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Entamoeba histolytica cysteine surface protein, putative 0.0366 0.3669 0.3805
Echinococcus multilocularis SH2 motif 0.0557 0.5718 0.5688
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0366 0.3669 0.3622
Brugia malayi Tyrosine-protein kinase abl-1 0.0926 0.9681 0.9686
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica hypothetical protein, conserved 0.0366 0.3669 0.3805
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Echinococcus granulosus tyrosine protein kinase ABL1 0.0922 0.9642 0.9639
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0104 0.086 0.0892
Loa Loa (eye worm) neuropeptide F receptor 0.0104 0.086 0.086
Loa Loa (eye worm) acetyltransferase 0.0145 0.1304 0.1304
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) protein kinase domain-containing protein 0.0366 0.3669 0.3671
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0119 0.007
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076
Echinococcus granulosus neuropeptide receptor 0.0104 0.086 0.079
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Brugia malayi C-terminal src kinase protein 1 0.0366 0.3669 0.3671
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0366 0.3669 0.362
Leishmania major protein kinase, putative 0.0366 0.3674 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Brugia malayi Protein kinase domain containing protein 0.0413 0.4172 0.4174
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0366 0.3669 0.362
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0104 0.086 0.086
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0366 0.3669 0.3671
Brugia malayi Cytochrome P450 family protein 0.0049 0.0266 0.0267
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0557 0.5718 0.5688
Brugia malayi Variant SH3 domain containing protein 0.0557 0.5718 0.5721
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0094 0.0097
Loa Loa (eye worm) melatonin receptor type 1A 0.0104 0.086 0.086
Trypanosoma brucei protein kinase, putative 0.0366 0.3674 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0104 0.086 0.079
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0104 0.086 0.079
Entamoeba histolytica receptor protein kinase, putative 0.0366 0.3669 0.3805
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0366 0.3669 0.9986
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi protein-tyrosine kinase 0.0952 0.9956 0.9961
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0104 0.086 0.079
Echinococcus multilocularis G-protein coupled receptor, putative 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0104 0.086 0.086
Schistosoma mansoni alpha-1 adrenergic receptor 0.0104 0.086 0.079
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0366 0.3669 0.3671
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0557 0.5718 0.5688
Schistosoma mansoni neuropeptide F-like receptor 0.0104 0.086 0.079
Giardia lamblia Kinase, NEK 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus biogenic amine 5HT receptor 0.0104 0.086 0.079
Echinococcus granulosus activin receptor type 0.0366 0.3674 0.3625
Leishmania major hypothetical protein, conserved 0.0366 0.3669 0.9987
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) TK/DDR protein kinase 0.0366 0.3669 0.3671
Brugia malayi hypothetical protein 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0926 0.9681 0.9684
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0557 0.5718 0.5721
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0366 0.3669 0.9986
Schistosoma mansoni suppressor of cytokine signaling 0.0557 0.5718 0.5688
Loa Loa (eye worm) hypothetical protein 0.0182 0.1695 0.1696
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Onchocerca volvulus 0.0104 0.086 0.0892
Echinococcus multilocularis mitogen activated protein kinase 14 0.0126 0.1099 0.1032
Echinococcus granulosus suppressor of cytokine signaling 6 0.0557 0.5718 0.5685
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Entamoeba histolytica serine/threonine kinase, putative 0.0366 0.3669 0.3805
Onchocerca volvulus 0.0366 0.3669 0.3805
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0366 0.3669 0.3671
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0557 0.5718 0.5685
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Schistosoma mansoni tyrosine kinase 0.0955 0.9995 1
Plasmodium vivax protein kinase, putative 0.0366 0.3669 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi SRC-1 0.0955 0.9995 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.086 0.079
Onchocerca volvulus 0.0031 0.0076 0.0079
Entamoeba histolytica protein kinase, putative 0.0395 0.3982 0.413
Echinococcus multilocularis serotonin receptor 0.0104 0.086 0.079
Loa Loa (eye worm) TK/ROR protein kinase 0.0366 0.3669 0.3671
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.1304 0.1304
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0284 0.2794 0.7555
Echinococcus multilocularis tyrosine protein kinase csk 0.0366 0.3669 0.3622
Trypanosoma cruzi protein kinase, putative 0.0366 0.3669 0.9986
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Echinococcus granulosus alpha 1A adrenergic receptor 0.0104 0.086 0.079
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0952 0.9956 0.996
Echinococcus multilocularis tyrosine protein kinase HCK 0.0395 0.3982 0.3938
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0104 0.086 0.079
Echinococcus granulosus 7TM GPCR rhodopsin 0.0104 0.086 0.079
Echinococcus granulosus dro:myosuppressin receptor 0.0104 0.086 0.079
Echinococcus multilocularis orexin receptor type 2 0.0104 0.086 0.079
Echinococcus multilocularis tyrosine kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.1695 0.1696
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0955 0.9995 1
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Echinococcus granulosus tensin 0.0557 0.5718 0.5685
Schistosoma mansoni signal transduction protein lnk-related 0.0557 0.5718 0.5688
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Onchocerca volvulus 0.0366 0.3669 0.3805
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.1304 0.1238
Echinococcus granulosus neuropeptide Y receptor 0.0104 0.086 0.079
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0119 0.0118
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0366 0.3669 0.3671
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus neuropeptide s receptor 0.0104 0.086 0.079
Echinococcus multilocularis 0.0557 0.5718 0.5688
Brugia malayi Receptor family ligand binding region containing protein 0.0366 0.3669 0.3671
Brugia malayi Protein kinase domain containing protein 0.0922 0.9642 0.9647
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0182 0.1695 0.1696
Brugia malayi Tensin 0.0557 0.5718 0.5721
Brugia malayi Protein kinase domain containing protein 0.0922 0.9642 0.9647
Onchocerca volvulus 0.0922 0.9642 1
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0366 0.3669 0.3622
Brugia malayi larval opioid receptor 0.0104 0.086 0.086
Brugia malayi tRNA modification GTPase TrmE family protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) TK/ABL protein kinase 0.0922 0.9642 0.9647
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Echinococcus granulosus neuropeptides capa receptor 0.0104 0.086 0.079
Schistosoma mansoni hypothetical protein 0.0557 0.5718 0.5688
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Echinococcus multilocularis dro:myosuppressin receptor 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0922 0.9642 0.9644
Echinococcus granulosus retinal guanylyl cyclase 2 0.0366 0.3669 0.362
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0203 0.0354
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0627 0.0651
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0366 0.3669 0.3671
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Schistosoma mansoni biogenic amine receptor 0.0104 0.086 0.079
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK/INSR protein kinase 0.0413 0.4172 0.4174
Echinococcus granulosus natriuretic peptide receptor 1 0.0366 0.3669 0.362
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0557 0.5718 0.5688
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0102 0.0024
Echinococcus granulosus SH2 motif 0.0557 0.5718 0.5685
Echinococcus granulosus transcription factor btf3 0.0035 0.0119 0.0043
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0126 0.1099 0.281
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0284 0.2794 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0413 0.4172 0.413
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Echinococcus granulosus tyrosine kinase 0.0366 0.3669 0.362
Brugia malayi P38 map kinase family protein 2 0.0126 0.1099 0.11
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0203 0.0307
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0104 0.086 0.079
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Brugia malayi beta-NAC-like protein 0.0035 0.0119 0.0119
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3674 0.381
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Trichomonas vaginalis protein tyrosine kinase, putative 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0955 0.9995 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0926 0.9681 0.9679
Giardia lamblia Protein 21.1 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) variant SH3 domain-containing protein 0.056 0.5758 0.5761
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0104 0.086 0.079
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK/CSK protein kinase 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK protein kinase 0.0395 0.3982 0.3984
Schistosoma mansoni serine/threonine protein kinase 0.0369 0.3708 0.3662
Schistosoma mansoni hypothetical protein 0.0339 0.3378 0.3329
Loa Loa (eye worm) hypothetical protein 0.0082 0.0627 0.0628
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni hypothetical protein 0.0366 0.3669 0.3622
Onchocerca volvulus 0.0104 0.086 0.0892
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0366 0.3669 0.3622
Schistosoma mansoni hypothetical protein 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.086 0.079
Echinococcus granulosus integrin linked protein kinase 0.0366 0.3669 0.362
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0366 0.3669 0.3622
Echinococcus granulosus tyrosine protein kinase Fyn 0.0955 0.9995 0.9995
Schistosoma mansoni tyrosine kinase 0.0079 0.0598 0.0526
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni opsin-like receptor 0.0104 0.086 0.079
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.3669 0.3671
Schistosoma mansoni protein kinase 0.0366 0.3674 0.3627
Trichomonas vaginalis TK family protein kinase 0.0366 0.3669 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0076 0.0076
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus g protein coupled receptor 0.0104 0.086 0.079
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0104 0.086 0.086
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0366 0.3669 0.3622
Echinococcus multilocularis sex peptide receptor 0.0104 0.086 0.079
Onchocerca volvulus 0.0557 0.5718 0.5931
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis allatostatin A receptor 0.0104 0.086 0.079
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0557 0.5718 0.5931
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus SH2 motif 0.0557 0.5718 0.5685
Echinococcus multilocularis tyrosine protein kinase 0.0366 0.3669 0.3622
Brugia malayi SH2 domain containing protein 0.0922 0.9642 0.9647
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0366 0.3669 0.3622
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Brugia malayi hypothetical protein 0.0557 0.5718 0.5721
Schistosoma mansoni amine GPCR 0.0104 0.086 0.079
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0284 0.2794 1
Onchocerca volvulus 0.0922 0.9642 1
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Onchocerca volvulus 0.0557 0.5718 0.5931
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0203 0.0307
Onchocerca volvulus 0.0104 0.086 0.0892
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0104 0.086 0.079
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0104 0.086 0.079
Schistosoma mansoni tensin 0.0557 0.5718 0.5688
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0623 0.6426 0.6402
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Echinococcus granulosus tyrosine protein kinase csk 0.0366 0.3669 0.362
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0955 0.9995 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0557 0.5718 0.5688
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0165 0.0248
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis tensin 0.0557 0.5718 0.5688
Schistosoma mansoni tyrosine kinase 0.0079 0.0598 0.0526
Onchocerca volvulus Neuropeptide F receptor homolog 0.0104 0.086 0.0892
Schistosoma mansoni neuropeptide receptor 0.0104 0.086 0.079
Echinococcus multilocularis activin receptor type 0.0366 0.3674 0.3627
Onchocerca volvulus 0.0031 0.0076 0.0079
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0104 0.086 0.079
Schistosoma mansoni tensin 0.0557 0.5718 0.5688
Schistosoma mansoni growth hormone secretagogue receptor 0.0104 0.086 0.079
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0102 0.0102
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Echinococcus multilocularis epidermal growth factor receptor 0.0514 0.5264 0.523
Brugia malayi Tachykinin-like peptides receptor 99D 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni growth factor receptor-bound protein 0.056 0.5758 0.5728
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0557 0.5723 0.5936
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni hypothetical protein 0.0339 0.3378 0.3329
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Echinococcus multilocularis g protein coupled receptor 0.0104 0.086 0.079
Schistosoma mansoni histamine h1 receptor 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Entamoeba histolytica SH2 domain containing protein 0.0557 0.5718 0.5931
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.1695 0.1696
Echinococcus granulosus retinal guanylyl cyclase 2 0.0366 0.3669 0.362
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0366 0.3669 0.362
Echinococcus granulosus tyrosine kinase 0.0922 0.9642 0.9639
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK protein kinase 0.0952 0.9956 0.9961
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0104 0.086 0.086
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Brugia malayi hypothetical protein 0.0031 0.0076 0.0076
Echinococcus granulosus tyrosine protein kinase csk 0.0366 0.3669 0.362
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni ephrin receptor 0.0366 0.3669 0.3622
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0955 0.9995 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0557 0.5718 0.5688
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0557 0.5718 0.5688
Brugia malayi Protein kinase domain containing protein 0.0922 0.9642 0.9647
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0366 0.3669 0.3805
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Echinococcus granulosus tyrosine protein kinase Src42A 0.0955 0.9995 0.9995
Trichomonas vaginalis AGC family protein kinase 0.0366 0.3669 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.1304 0.1238
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Echinococcus multilocularis mitogen activated protein kinase 11 0.0126 0.1099 0.1032
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus granulosus SH2 domain containing protein 7 0.0557 0.5718 0.5685
Brugia malayi Immunoglobulin I-set domain containing protein 0.0366 0.3669 0.3671
Trichomonas vaginalis rotamase, putative 0.0033 0.0102 0.0024
Schistosoma mansoni tyrosine kinase 0.0445 0.4521 0.4482
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0366 0.3669 0.3805
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.1695 0.1633
Echinococcus granulosus tyrosine protein kinase Blk 0.0952 0.9956 0.9955
Onchocerca volvulus 0.0104 0.086 0.0892
Echinococcus granulosus insulin receptor 0.0413 0.4172 0.4127
Schistosoma mansoni tensin-related 0.0557 0.5718 0.5688
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0955 0.9995 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0926 0.9681 0.9684
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Entamoeba histolytica serine/threonine kinase, putative 0.0366 0.3669 0.3805
Schistosoma mansoni amine GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0104 0.086 0.079
Schistosoma mansoni nck2/grb4 0.056 0.5758 0.5728
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.086 0.079
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Schistosoma mansoni hypothetical protein 0.0104 0.086 0.079
Echinococcus multilocularis G protein coupled receptor 139 0.0104 0.086 0.079
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0366 0.3669 0.3622
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.3669 0.3622
Schistosoma mansoni growth factor receptor-bound protein 0.056 0.5758 0.5728
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0284 0.2794 0.7565
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0557 0.5718 0.5688
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Echinococcus multilocularis mitogen activated protein kinase 14 0.0126 0.1099 0.1032
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0165 0.0171
Echinococcus granulosus biogenic amine 5HT receptor 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Schistosoma mansoni transcription factor btf3 0.0035 0.0119 0.0043
Echinococcus multilocularis g-protein coupled receptor 0.0104 0.086 0.079
Echinococcus granulosus neuropeptides capa receptor 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni GTPase activating protein 0.0557 0.5718 0.5688
Schistosoma mansoni opsin-like receptor 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0514 0.5264 0.523
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) TYRA-2 protein 0.0104 0.086 0.086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.086 0.079
Onchocerca volvulus 0.0366 0.3669 0.3805
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0366 0.3674 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0104 0.086 0.079
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0076 0.0076
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0366 0.3669 0.3805
Echinococcus multilocularis fmrfamide receptor 0.0104 0.086 0.079
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0926 0.9681 0.9684
Echinococcus multilocularis tyrosine protein kinase Blk 0.0952 0.9956 0.996
Schistosoma mansoni vav2 0.0557 0.5718 0.5688
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0104 0.086 0.086
Echinococcus multilocularis somatostatin receptor 0.0104 0.086 0.079
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus granulosus epidermal growth factor receptor 0.0514 0.5264 0.5227
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0081 0.0005
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Entamoeba histolytica tyrosin kinase, putative 0.0366 0.3669 0.3805
Echinococcus multilocularis activated cdc42 kinase 1 0.0366 0.3669 0.3622
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni adenoreceptor 0.0104 0.086 0.079
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Schistosoma mansoni protein tyrosine kinase 0.0366 0.3669 0.3622
Echinococcus multilocularis neuropeptides capa receptor 0.0104 0.086 0.079
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0104 0.086 0.086
Brugia malayi neuropeptide F receptor 0.0104 0.086 0.086
Onchocerca volvulus 0.0922 0.9642 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.126 0.1193
Schistosoma mansoni tyrosine kinase 0.0926 0.9681 0.9684
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.086 0.079
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.056 0.5758 0.5728
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0119 0.0118
Echinococcus multilocularis natriuretic peptide receptor 1 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis neuropeptide receptor A26 0.0104 0.086 0.079
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0366 0.3669 0.362
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Onchocerca volvulus 0.0031 0.0076 0.0079
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0366 0.3669 0.3671
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus granulosus kinase suppressor of Ras 1 0.0366 0.3669 0.362
Onchocerca volvulus 0.0557 0.5718 0.5931
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0922 0.9642 0.9639
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0104 0.086 0.079
Echinococcus granulosus tyrosine protein kinase HCK 0.0395 0.3982 0.3936
Schistosoma mansoni tensin 0.0557 0.5718 0.5688
Echinococcus multilocularis receptor type guanylyl cyclase 0.0366 0.3669 0.3622
Echinococcus granulosus expressed protein 0.0033 0.0102 0.0026
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0126 0.1099 0.281
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica serine/threonine kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0955 0.9995 0.9995
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0922 0.9642 0.9647
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0557 0.5718 0.5685
Brugia malayi RhoGAP domain containing protein 0.0557 0.5718 0.5721
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) RGC/RGC protein kinase 0.0366 0.3669 0.3671
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0203 0.0128
Brugia malayi G protein-coupled receptor 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0366 0.3669 0.3622
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis SH2 motif 0.0557 0.5718 0.5688
Entamoeba histolytica protein kinase, putative 0.0557 0.5723 0.5936
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Onchocerca volvulus 0.0104 0.086 0.0892
Schistosoma mansoni hypothetical protein 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0952 0.9956 0.9955
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.3669 0.3671
Brugia malayi Melatonin receptor type 1A 0.0104 0.086 0.086
Trypanosoma brucei Pseudokinase, putative 0.0366 0.3669 0.9986
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0557 0.5718 0.5721
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0094 0.0048
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis neuropeptide receptor 0.0104 0.086 0.079
Entamoeba histolytica tyrosin kinase, putative 0.0366 0.3669 0.3805
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0119 0.0123
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Schistosoma mansoni protein kinase 0.0366 0.3669 0.3622
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Onchocerca volvulus 0.0104 0.086 0.0892
Echinococcus multilocularis growth factor receptor bound protein 2 0.056 0.5758 0.5728
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0366 0.3674 0.3625
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni tyrosine kinase 0.0413 0.4172 0.413
Onchocerca volvulus 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0102 0.0102
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0366 0.3669 0.3622
Brugia malayi hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Onchocerca volvulus 0.0922 0.9642 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0586 0.6032 0.6001
Plasmodium falciparum protein kinase, putative 0.0366 0.3674 1
Schistosoma mansoni neuropeptide receptor 0.0104 0.086 0.079
Echinococcus multilocularis N chimaerin 0.0557 0.5718 0.5688
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0955 0.9995 1
Echinococcus multilocularis neuropeptide Y receptor 0.0104 0.086 0.079
Echinococcus multilocularis neuropeptide receptor 0.0104 0.086 0.079
Schistosoma mansoni tyrosine kinase 0.0445 0.4521 0.4482
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0366 0.3669 0.3805
Schistosoma mansoni serine/threonine protein kinase 0.0366 0.3669 0.3622
Echinococcus granulosus SH2 domain containing adapter protein F 0.0557 0.5718 0.5685
Brugia malayi Dopamine receptor 0.0104 0.086 0.086
Onchocerca volvulus 0.0922 0.9642 1
Echinococcus granulosus neuropeptide receptor A26 0.0104 0.086 0.079
Loa Loa (eye worm) TK protein kinase 0.0366 0.3669 0.3671
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0104 0.086 0.079
Echinococcus granulosus suppressor of cytokine signaling 7 0.0557 0.5718 0.5685
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi RE15519p 0.0104 0.086 0.086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Echinococcus multilocularis mitogen activated protein kinase 11 0.0126 0.1099 0.1032
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) serotonin transporter b 0.0182 0.1695 0.1696
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0284 0.2794 1
Trypanosoma cruzi protein kinase, putative 0.0366 0.3669 0.9986
Schistosoma mansoni tyrosine kinase 0.0366 0.3669 0.3622
Schistosoma mansoni biogenic amine receptor 0.0104 0.086 0.079
Echinococcus multilocularis ephrin type A receptor 4 A 0.0366 0.3669 0.3622
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0366 0.3669 0.3622
Echinococcus multilocularis tyrosine protein kinase shark 0.0922 0.9642 0.9644
Plasmodium falciparum protein kinase, putative 0.0366 0.3669 0.9986
Schistosoma mansoni tyrosine kinase 0.0413 0.4172 0.413
Brugia malayi Variant SH3 domain containing protein 0.056 0.5758 0.5761
Echinococcus granulosus growth factor receptor bound protein 2 0.056 0.5758 0.5725
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0955 0.9995 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0366 0.3669 0.3622
Echinococcus granulosus sex peptide receptor 0.0104 0.086 0.079
Echinococcus granulosus tyrosine protein kinase shark 0.0922 0.9642 0.9639
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.086 0.079
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0445 0.4521 0.4479
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Loa Loa (eye worm) hypothetical protein 0.056 0.5758 0.5761
Loa Loa (eye worm) SH2 domain-containing protein 0.0557 0.5718 0.5721
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Echinococcus granulosus tyrosine protein kinase Srms 0.0922 0.9642 0.9639
Brugia malayi Variant SH3 domain containing protein 0.056 0.5758 0.5761
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Echinococcus granulosus tyrosine protein kinase Fyn 0.0955 0.9995 0.9995
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0366 0.3674 1
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0119 0.0118
Echinococcus multilocularis c src tyrosine kinase 0.0926 0.9681 0.9684
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus multilocularis epidermal growth factor receptor 0.0445 0.4521 0.4482
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Schistosoma mansoni tensin-related 0.0557 0.5718 0.5688
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0955 0.9995 1
Schistosoma mansoni myosin xvIII 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) STAT protein 0.0557 0.5718 0.5721
Schistosoma mansoni neuropeptide receptor 0.0104 0.086 0.079
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0366 0.3669 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0104 0.086 0.079
Trichomonas vaginalis conserved hypothetical protein 0.0366 0.3669 1
Entamoeba histolytica protein kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0557 0.5718 0.5721
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076
Loa Loa (eye worm) TK/FAK protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Brugia malayi Serotonin receptor 0.0104 0.086 0.086
Schistosoma mansoni shc transforming protein 0.0557 0.5718 0.5688
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0557 0.5718 0.5685
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis neuropeptide Y receptor 0.0104 0.086 0.079
Echinococcus granulosus peptide allatostatin:somatostatin 0.0104 0.086 0.079
Entamoeba histolytica tyrosin kinase, putative 0.0366 0.3669 0.3805
Echinococcus granulosus 7tm_1 domain containing protein 0.0104 0.086 0.079
Echinococcus multilocularis tyrosine protein kinase csk 0.0366 0.3669 0.3622
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus multilocularis transfer RNA-Thr 0.0366 0.3669 0.3622
Loa Loa (eye worm) TK/ALK protein kinase 0.0366 0.3669 0.3671
Brugia malayi Sex muscle abnormal protein 5 0.056 0.5758 0.5761
Echinococcus granulosus hypothetical protein 0.0796 0.8282 0.8268
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0104 0.086 0.079
Echinococcus multilocularis geminin 0.0339 0.3378 0.3329
Echinococcus multilocularis SH2 motif 0.0557 0.5718 0.5688
Entamoeba histolytica serine/threonine kinase, putative 0.0366 0.3669 0.3805
Echinococcus granulosus neuropeptide receptor 0.0104 0.086 0.079
Echinococcus granulosus g protein coupled receptor 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) TK/EGFR protein kinase 0.0514 0.5264 0.5266
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0366 0.3669 0.3622
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.086 0.079
Entamoeba histolytica ankyrin repeat protein 0.0366 0.3669 0.3805
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0366 0.3669 1
Trichomonas vaginalis STE family protein kinase 0.0366 0.3669 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0586 0.6032 0.6004
Loa Loa (eye worm) serine/threonine protein kinase 0.0366 0.3669 0.3671
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076
Onchocerca volvulus 0.0557 0.5718 0.5931
Echinococcus multilocularis serotonin receptor 0.0104 0.086 0.079
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0557 0.5718 0.5685
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) neuropeptide F receptor 0.0104 0.086 0.086
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0519 0.5313 0.5316
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0203 0.0354
Echinococcus granulosus NCK adaptor protein 0.056 0.5758 0.5725
Schistosoma mansoni amine GPCR 0.0104 0.086 0.079
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0922 0.9642 1
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0119 0.007
Brugia malayi hypothetical protein 0.0922 0.9642 0.9647
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0366 0.3669 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0104 0.086 0.086
Onchocerca volvulus 0.0104 0.086 0.0892
Echinococcus multilocularis transcription factor btf3 0.0035 0.0119 0.0043
Echinococcus granulosus mitogen activated protein kinase 14 0.0126 0.1099 0.1031
Onchocerca volvulus 0.0922 0.9642 1
Onchocerca volvulus 0.0104 0.086 0.0892
Entamoeba histolytica hypothetical protein 0.0035 0.0119 0.0123
Echinococcus multilocularis serotonin transporter 0.0182 0.1695 0.1633
Echinococcus granulosus epidermal growth factor receptor 0.0445 0.4521 0.4479
Brugia malayi bone morphogenetic protein type 1 receptor 0.0366 0.3669 0.3671
Echinococcus multilocularis 0.0046 0.0241 0.0167
Echinococcus granulosus receptor type guanylyl cyclase 0.0366 0.3669 0.362
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0104 0.086 0.079
Echinococcus multilocularis insulin receptor 0.0413 0.4172 0.413
Entamoeba histolytica hypothetical protein 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0366 0.3669 0.3671
Schistosoma mansoni hypothetical protein 0.0557 0.5718 0.5688
Echinococcus granulosus allatostatin A receptor 0.0104 0.086 0.079
Plasmodium vivax tyrosine kinase-like protein, putative 0.0366 0.3669 1
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0366 0.3669 0.9986
Echinococcus granulosus tm gpcr rhodopsin 0.0623 0.6426 0.6399
Echinococcus granulosus raf serine:threonine protein kinase 0.0366 0.3669 0.362
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0366 0.3674 1
Brugia malayi SH2 domain containing protein 0.0557 0.5718 0.5721
Brugia malayi Protein kinase domain containing protein 0.0366 0.3669 0.3671
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Schistosoma mansoni rotamase 0.0033 0.0102 0.0026
Onchocerca volvulus 0.0104 0.086 0.0892
Onchocerca volvulus 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0082 0.0627 0.0651
Schistosoma mansoni tyrosine kinase 0.0926 0.9681 0.9684
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0557 0.5718 0.5688
Schistosoma mansoni serine/threonine RGC 0.0366 0.3669 0.3622
Entamoeba histolytica protein kinase domain containing protein 0.0366 0.3669 0.3805
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0094 0.0255
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Toxoplasma gondii protein kinase 0.0366 0.3669 0.9986
Echinococcus multilocularis signal transduction protein lnk realted 0.0557 0.5718 0.5688
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Loa Loa (eye worm) G-protein coupled receptor 0.0104 0.086 0.086
Brugia malayi Protein kinase domain containing protein 0.0922 0.9642 0.9647
Schistosoma mansoni SH2A 0.0557 0.5718 0.5688
Brugia malayi G protein-coupled receptor F59B2.13 0.0104 0.086 0.086
Loa Loa (eye worm) hypothetical protein 0.0519 0.5313 0.5316
Entamoeba histolytica ankyrin repeat protein 0.0366 0.3669 0.3805
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0104 0.086 0.079
Entamoeba histolytica serine/threonine kinase, putative 0.0366 0.3669 0.3805
Echinococcus multilocularis tyrosine kinase 0.0922 0.9642 0.9644
Loa Loa (eye worm) hypothetical protein 0.0104 0.086 0.086
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0076 0.0076
Onchocerca volvulus 0.0104 0.086 0.0892
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.086 0.079
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Onchocerca volvulus 0.0182 0.1695 0.1758
Loa Loa (eye worm) TK/FER protein kinase 0.0922 0.9642 0.9647
Loa Loa (eye worm) TK/ACK protein kinase 0.0366 0.3669 0.3671
Loa Loa (eye worm) SH2 domain-containing protein 0.0557 0.5718 0.5721
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0266 0.0267
Brugia malayi ORL1-like opioid receptor 0.0104 0.086 0.086
Onchocerca volvulus 0.0104 0.086 0.0892
Schistosoma mansoni ephrin receptor 0.0366 0.3669 0.3622
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0119 0.007
Trichomonas vaginalis TKL family protein kinase 0.0366 0.3669 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0366 0.3669 0.362
Echinococcus granulosus fmrfamide receptor 0.0104 0.086 0.079
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0366 0.3669 0.3671
Entamoeba histolytica tyrosine kinase, putative 0.0366 0.3669 0.3805
Loa Loa (eye worm) hypothetical protein 0.0031 0.0076 0.0076

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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