Detailed information for compound 1753170

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 430.537 | Formula: C24H34N2O5
  • H donors: 1 H acceptors: 3 LogP: 2.74 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)[C@@]12CCCC=C2N(C(=O)[C@@H](C1)CC(=O)NCCC(C)C)Cc1ccco1
  • InChi: 1S/C24H34N2O5/c1-4-30-23(29)24-11-6-5-9-20(24)26(16-19-8-7-13-31-19)22(28)18(15-24)14-21(27)25-12-10-17(2)3/h7-9,13,17-18H,4-6,10-12,14-16H2,1-3H3,(H,25,27)/t18-,24+/m1/s1
  • InChiKey: UDCXDSVMXPZHBG-KOSHJBKYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi hypothetical protein 0.0951 0.3918 0.3874
Schistosoma mansoni opsin-like receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis g-protein coupled receptor 0.0104 0.0306 0.0234
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.0306 0.0234
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0104 0.0306 0.0234
Schistosoma mansoni hypothetical protein 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0104 0.0306 0.0234
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0057 0.0108 0.2801
Echinococcus granulosus biogenic amine 5HT receptor 0.0104 0.0306 0.0234
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0104 0.0306 0.0234
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.1426 0.5944 0.5914
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0222 0.0811 0.2027
Echinococcus multilocularis 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis tyrosine kinase 0.0951 0.3918 0.3874
Schistosoma mansoni hypothetical protein 0.0951 0.3918 0.3874
Echinococcus granulosus lysine specific demethylase 6a 0.0222 0.0811 0.0743
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.0306 0.0234
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0121 0.0379 1
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0951 0.3918 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0951 0.3918 0.3874
Echinococcus granulosus sex peptide receptor 0.0104 0.0306 0.0234
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0121 0.0379 0.0308
Echinococcus granulosus g-protein coupled receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.1426 0.5944 0.5944
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0171 0.059 0.1459
Schistosoma mansoni amine GPCR 0.0104 0.0306 0.0234
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus multilocularis g protein coupled receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase pr2 0.0951 0.3918 0.3874
Loa Loa (eye worm) dihydrofolate reductase 0.0049 0.0073 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0951 0.3918 0.3874
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0054 0.0092 0.2374
Loa Loa (eye worm) protein kinase domain-containing protein 0.0951 0.3918 0.3918
Chlamydia trachomatis dihydrofolate reductase 0.0049 0.0073 0.5
Onchocerca volvulus 0.0104 0.0306 0.0216
Brugia malayi jmjC domain containing protein 0.0376 0.1467 0.1404
Loa Loa (eye worm) TK/ACK protein kinase 0.0951 0.3918 0.3918
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1426 0.5944 0.5914
Schistosoma mansoni neuropeptide receptor 0.0104 0.0306 0.0234
Brugia malayi Variant SH3 domain containing protein 0.1426 0.5944 0.5914
Echinococcus multilocularis neuropeptide receptor 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Mycobacterium ulcerans polyketide synthase Pks13 0.0086 0.0229 0.5756
Schistosoma mansoni tyrosine kinase 0.2377 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.1426 0.5944 0.5907
Schistosoma mansoni jumonji/arid domain-containing protein 0.0704 0.2866 0.2814
Onchocerca volvulus 0.0951 0.3918 0.3862
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1426 0.5944 0.5914
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0543 0.2178 0.2178
Echinococcus granulosus PHD finger protein rhinoceros 0.0543 0.2178 0.212
Loa Loa (eye worm) RGC/RGC protein kinase 0.0951 0.3918 0.3918
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0951 0.3918 0.3874
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0041 0.0039 0.0973
Onchocerca volvulus 0.0951 0.3918 0.3862
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0951 0.3918 0.3874
Schistosoma mansoni serine/threonine protein kinase 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) jmjC domain-containing protein 0.0222 0.0811 0.0811
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Loa Loa (eye worm) TK/RYK protein kinase 0.0951 0.3918 0.3918
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0057 0.0108 0.2801
Echinococcus multilocularis SH2 motif 0.1426 0.5944 0.5914
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0104 0.0306 0.0234
Echinococcus granulosus G protein coupled receptor 139 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0104 0.0306 0.0234
Brugia malayi Guanylyl cyclase protein 23 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0046 0.006 0.099
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus multilocularis allatostatin A receptor 0.0104 0.0306 0.0234
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0543 0.2178 0.212
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0056 0.01 0.2602
Brugia malayi AMP-binding enzyme family protein 0.0054 0.0092 0.0018
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis epidermal growth factor receptor 0.0951 0.3918 0.3874
Echinococcus granulosus g protein coupled receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0951 0.3918 0.3918
Echinococcus multilocularis sex peptide receptor 0.0104 0.0306 0.0234
Echinococcus granulosus tyrosine protein kinase Blk 0.2377 1 1
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0951 0.3918 0.3874
Echinococcus multilocularis lysine specific demethylase 5A 0.0704 0.2866 0.2814
Brugia malayi Melatonin receptor type 1A 0.0104 0.0306 0.0234
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0951 0.3918 0.3862
Trichomonas vaginalis CAMK family protein kinase 0.0951 0.3918 1
Schistosoma mansoni shc transforming protein 0.1426 0.5944 0.5914
Echinococcus multilocularis tyrosine protein kinase Fgr 0.2377 1 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.2377 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0951 0.3918 0.3874
Echinococcus multilocularis tyrosine protein kinase csk 0.0951 0.3918 0.3874
Loa Loa (eye worm) neuropeptide F receptor 0.0104 0.0306 0.0306
Schistosoma mansoni biogenic amine receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis neuropeptides capa receptor 0.0104 0.0306 0.0234
Brugia malayi neuropeptide F receptor 0.0104 0.0306 0.0234
Brugia malayi jmjC domain containing protein 0.1825 0.7646 0.7629
Echinococcus multilocularis raf serine:threonine protein kinase 0.0951 0.3918 0.3874
Echinococcus granulosus SH2 domain containing adapter protein F 0.1426 0.5944 0.5914
Echinococcus granulosus hypothetical protein 0.1426 0.5944 0.5914
Schistosoma mansoni hypothetical protein 0.0543 0.2178 0.212
Brugia malayi Protein kinase domain containing protein 0.2377 1 1
Schistosoma mansoni tensin 0.1426 0.5944 0.5914
Echinococcus granulosus g protein coupled receptor 0.0104 0.0306 0.0234
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0048 0.0067 0.1188
Echinococcus granulosus natriuretic peptide receptor 1 0.0951 0.3918 0.3874
Echinococcus granulosus epidermal growth factor receptor 0.0951 0.3918 0.3874
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0086 0.0229 0.6011
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0121 0.0379 1
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0061 0.0123 0.3204
Echinococcus multilocularis tyrosine protein kinase Blk 0.2377 1 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0951 0.3918 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Echinococcus granulosus alpha 1A adrenergic receptor 0.0104 0.0306 0.0234
Echinococcus granulosus neuropeptide s receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tensin 0.1426 0.5944 0.5914
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0222 0.0811 0.2027
Loa Loa (eye worm) TK/ABL protein kinase 0.2377 1 1
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0046 0.006 0.099
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1426 0.5944 0.5914
Onchocerca volvulus 0.0951 0.3918 0.3862
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Brugia malayi ephrin receptor 1 precursor 0.0951 0.3918 0.3874
Schistosoma mansoni vav2 0.1426 0.5944 0.5914
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0057 0.0108 0.234
Echinococcus multilocularis protein kinase 0.0951 0.3918 0.3874
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) SRC-1 0.2377 1 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Onchocerca volvulus 0.0104 0.0306 0.0216
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Brugia malayi Dopamine receptor protein 1 0.0104 0.0306 0.0234
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0104 0.0306 0.0306
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.0306 0.0234
Brugia malayi SH2 domain containing protein 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus receptor type guanylyl cyclase 0.0951 0.3918 0.3874
Onchocerca volvulus 0.0951 0.3918 0.3862
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Brugia malayi jmjC domain containing protein 0.0704 0.2866 0.2814
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Schistosoma mansoni tensin-related 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.2377 1 1
Plasmodium vivax protein kinase, putative 0.0951 0.3918 1
Schistosoma mansoni jumonji domain containing protein 0.146 0.6088 0.6059
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0104 0.0306 0.0234
Mycobacterium ulcerans thioesterase 0.0048 0.0067 0.1188
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0109 0.0327 0.0256
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0104 0.0306 0.0234
Onchocerca volvulus 0.1426 0.5944 0.5907
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Onchocerca volvulus 0.0951 0.3918 0.3862
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Echinococcus multilocularis neuropeptide Y receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0951 0.3918 0.3874
Brugia malayi Variant SH3 domain containing protein 0.1426 0.5944 0.5914
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0104 0.0306 0.0234
Onchocerca volvulus 0.1426 0.5944 0.5907
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0951 0.3918 0.3874
Echinococcus multilocularis G-protein coupled receptor, putative 0.0104 0.0306 0.0234
Schistosoma mansoni phosphatidylserine receptor 0.0222 0.0811 0.0743
Echinococcus granulosus allatostatin A receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.2377 1 1
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0951 0.3918 0.3918
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Echinococcus multilocularis phd:f box containing protein 0.0222 0.0811 0.0743
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Onchocerca volvulus 0.0104 0.0306 0.0216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Echinococcus granulosus activated cdc42 kinase 1 0.0951 0.3918 0.3874
Schistosoma mansoni phd/f-box containing protein 0.0222 0.0811 0.0743
Brugia malayi Serotonin receptor 0.0104 0.0306 0.0234
Schistosoma mansoni signal transduction protein lnk-related 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0951 0.3918 0.3874
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0222 0.0811 0.0665
Echinococcus multilocularis kinase suppressor of Ras 1 0.0951 0.3918 0.3874
Toxoplasma gondii type I fatty acid synthase, putative 0.0041 0.0037 0.004
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1426 0.5944 0.3331
Loa Loa (eye worm) PHD-finger family protein 0.0543 0.2178 0.2178
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus tyrosine protein kinase csk 0.0951 0.3918 0.3874
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0049 0.0073 0.1892
Echinococcus granulosus jumonji domain containing protein 0.0756 0.3084 0.3033
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0104 0.0306 0.0234
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0057 0.0108 0.2801
Echinococcus multilocularis SHC transforming protein 3 0.1426 0.5944 0.5914
Giardia lamblia Kinase, NEK 0.0951 0.3918 1
Echinococcus multilocularis thymidylate synthase 0.0121 0.0379 0.0308
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Plasmodium vivax tyrosine kinase-like protein, putative 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni nck2/grb4 0.1426 0.5944 0.5914
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Leishmania major hypothetical protein, conserved 0.0222 0.0811 0.0665
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Trichomonas vaginalis protein kinase atn1, putative 0.0951 0.3918 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0951 0.3918 1
Brugia malayi G protein-coupled receptor 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Mycobacterium tuberculosis Probable thioesterase TesA 0.0048 0.0067 0.1719
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Loa Loa (eye worm) RGC/RGC protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0951 0.3918 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis protein tyrosine kinase 0.0951 0.3918 0.3874
Brugia malayi PHD-finger family protein 0.0543 0.2178 0.212
Schistosoma mansoni neuropeptide receptor 0.0104 0.0306 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi C-terminal src kinase protein 1 0.0951 0.3918 0.3874
Echinococcus multilocularis neuropeptide s receptor 0.0104 0.0306 0.0234
Echinococcus granulosus NCK adaptor protein 0.1426 0.5944 0.5914
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0951 0.3918 0.3874
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0104 0.0306 0.0306
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Echinococcus multilocularis NCK adaptor protein 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Trypanosoma brucei Flagellum attachment zone protein 20 0.0951 0.3918 1
Echinococcus granulosus phd:f box containing protein 0.0222 0.0811 0.0743
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Brugia malayi protein-tyrosine kinase 0.2377 1 1
Echinococcus granulosus dro:myosuppressin receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine kinase 0.2377 1 1
Giardia lamblia Kinase 0.0951 0.3918 1
Brugia malayi Protein kinase domain containing protein 0.2377 1 1
Echinococcus granulosus activated cdc42 kinase 1 0.0951 0.3918 0.3874
Loa Loa (eye worm) TK/INSR protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.2377 1 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.2377 1 1
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0177 0.0619 0.1534
Schistosoma mansoni neuropeptide receptor 0.0104 0.0306 0.0234
Giardia lamblia Kinase, NEK 0.0951 0.3918 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0104 0.0306 0.0234
Onchocerca volvulus 0.2377 1 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0951 0.3918 1
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0046 0.006 0.099
Schistosoma mansoni serine/threonine protein kinase 0.0951 0.3918 0.3874
Schistosoma mansoni SH2A 0.1426 0.5944 0.5914
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Schistosoma mansoni serine/threonine RGC 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0951 0.3918 0.3874
Echinococcus granulosus neuropeptides capa receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1426 0.5944 0.5944
Brugia malayi jmjC domain containing protein 0.0222 0.0811 0.0743
Brugia malayi AKH receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1426 0.5944 0.5944
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0951 0.3918 0.3874
Brugia malayi Tyrosine-protein kinase PR2 0.0951 0.3918 0.3874
Echinococcus granulosus fmrfamide receptor 0.0104 0.0306 0.0234
Onchocerca volvulus 0.2377 1 1
Echinococcus multilocularis g protein coupled receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tensin 0.1426 0.5944 0.5914
Onchocerca volvulus 0.0104 0.0306 0.0216
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Onchocerca volvulus 0.0104 0.0306 0.0216
Plasmodium falciparum phd finger protein, putative 0.0543 0.2178 0.477
Brugia malayi ORL1-like opioid receptor 0.0104 0.0306 0.0234
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0222 0.0811 0.0743
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0061 0.0123 0.3204
Echinococcus granulosus tensin 0.1426 0.5944 0.5914
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2377 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0104 0.0306 0.0234
Echinococcus granulosus tyrosine kinase 0.2377 1 1
Loa Loa (eye worm) SH2 domain-containing protein 0.1426 0.5944 0.5944
Schistosoma mansoni amine GPCR 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni adapter molecule crk 0.1426 0.5944 0.5914
Brugia malayi F/Y-rich N-terminus family protein 0.0177 0.0619 0.055
Echinococcus granulosus neuropeptide FF receptor 2 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK/Met protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni opsin-like receptor 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Onchocerca volvulus 0.0104 0.0306 0.0216
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.1426 0.5944 0.5914
Loa Loa (eye worm) TK/EGFR protein kinase 0.0951 0.3918 0.3918
Leishmania major protein kinase, putative 0.0951 0.3918 1
Echinococcus multilocularis c src tyrosine kinase 0.2377 1 1
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0951 0.3918 0.3918
Brugia malayi Dopamine receptor protein 2 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi Dopamine receptor 0.0104 0.0306 0.0234
Trypanosoma brucei protein kinase, putative 0.0951 0.3918 1
Brugia malayi integrin-linked kinase 0.0951 0.3918 0.3874
Plasmodium falciparum JmjC domain-containing protein, putative 0.0222 0.0811 0.0665
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0222 0.0811 0.0743
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Echinococcus multilocularis suppressor of cytokine signaling 6 0.1426 0.5944 0.5914
Echinococcus multilocularis activin receptor type 0.0951 0.3918 0.3874
Echinococcus multilocularis FL cytokine receptor 0.0951 0.3918 0.3874
Echinococcus granulosus epidermal growth factor receptor 0.0951 0.3918 0.3874
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0104 0.0306 0.0234
Echinococcus granulosus tyrosine protein kinase Fyn 0.2377 1 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0978 0.4033 0.4033
Onchocerca volvulus 0.0104 0.0306 0.0216
Loa Loa (eye worm) G-protein coupled receptor 0.0104 0.0306 0.0306
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.0306 0.0234
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0177 0.0619 0.0088
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0104 0.0306 0.0306
Echinococcus multilocularis serotonin receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Loa Loa (eye worm) hypothetical protein 0.0222 0.0811 0.0811
Loa Loa (eye worm) SH2 domain-containing protein 0.1426 0.5944 0.5944
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0951 0.3918 0.3874
Trichomonas vaginalis STE family protein kinase 0.0951 0.3918 1
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Schistosoma mansoni amine GPCR 0.0104 0.0306 0.0234
Schistosoma mansoni alpha-1 adrenergic receptor 0.0104 0.0306 0.0234
Echinococcus granulosus ephrin type A receptor 4 A 0.0951 0.3918 0.3874
Onchocerca volvulus 0.1426 0.5944 0.5907
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Loa Loa (eye worm) jmjC domain-containing protein 0.1121 0.4643 0.4643
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Plasmodium vivax tyrosine kinase-like protein, putative 0.0951 0.3918 1
Echinococcus multilocularis somatostatin receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein kinase pr2 0.0951 0.3918 0.3874
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.2377 1 1
Schistosoma mansoni growth factor receptor-bound protein 0.1426 0.5944 0.5914
Brugia malayi Raf kinase 0.0951 0.3918 0.3874
Brugia malayi cytokine inducible SH2-containing protein 5 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0951 0.3918 0.3874
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Brugia malayi hypothetical protein 0.2377 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0104 0.0306 0.0234
Schistosoma mansoni biogenic amine (5HT) receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Loa Loa (eye worm) TK/ROR protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Plasmodium vivax JmjC domain containing protein 0.0222 0.0811 0.0665
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Echinococcus granulosus retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Echinococcus multilocularis SH2 motif 0.1426 0.5944 0.5914
Schistosoma mansoni neuropeptide F-like receptor 0.0104 0.0306 0.0234
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Leishmania major hypothetical protein, conserved 0.0951 0.3918 1
Brugia malayi Furin-like cysteine rich region family protein 0.0951 0.3918 0.3874
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0104 0.0306 0.0234
Mycobacterium leprae Polyketide synthase Pks13 0.0086 0.0229 0.5756
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0951 0.3918 0.3874
Brugia malayi Receptor family ligand binding region containing protein 0.0951 0.3918 0.3874
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0951 0.3918 0.3874
Echinococcus multilocularis JmjC domain containing protein 4 0.0222 0.0811 0.0743
Schistosoma mansoni hypothetical protein 0.0104 0.0306 0.0234
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0104 0.0306 0.0234
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0056 0.01 0.2602
Onchocerca volvulus Tyrosine kinase homolog 0.0951 0.3918 0.3862
Brugia malayi Tachykinin-like peptides receptor 99D 0.0104 0.0306 0.0234
Onchocerca volvulus 0.0104 0.0306 0.0216
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Echinococcus granulosus activin receptor type 0.0951 0.3918 0.3874
Echinococcus multilocularis neuropeptide Y receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0104 0.0306 0.0234
Schistosoma mansoni hypothetical protein 0.0104 0.0306 0.0234
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.2377 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0951 0.3918 0.3874
Mycobacterium ulcerans thioesterase TesA 0.0048 0.0067 0.1188
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0086 0.0229 0.6011
Schistosoma mansoni GTPase activating protein 0.1426 0.5944 0.5914
Echinococcus multilocularis tyrosine protein kinase csk 0.0951 0.3918 0.3874
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Brugia malayi hypothetical protein 0.0951 0.3918 0.3874
Echinococcus granulosus JmjC domain containing protein 4 0.0222 0.0811 0.0743
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus suppressor of cytokine signaling 7 0.1426 0.5944 0.5914
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Brugia malayi putative neuropeptide receptor NPR1 0.0104 0.0306 0.0234
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0104 0.0306 0.0234
Mycobacterium ulcerans thymidylate synthase 0.0121 0.0379 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0951 0.3918 0.3918
Onchocerca volvulus 0.1426 0.5944 0.5907
Echinococcus granulosus thymidylate synthase 0.0121 0.0379 0.0308
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0951 0.3918 0.3874
Schistosoma mansoni tensin 0.1426 0.5944 0.5914
Trypanosoma brucei Pseudokinase, putative 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1426 0.5944 0.5914
Schistosoma mansoni amine GPCR 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0222 0.0811 0.0811
Echinococcus multilocularis tyrosine protein kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Onchocerca volvulus 0.0104 0.0306 0.0216
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1426 0.5944 0.5914
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus fibroblast growth factor receptor 4 0.0951 0.3918 0.3874
Schistosoma mansoni growth factor receptor-bound protein 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Echinococcus granulosus SHC transforming protein 3 0.1426 0.5944 0.5914
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1426 0.5944 0.5914
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0057 0.0108 0.234
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0222 0.0811 0.0743
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Brugia malayi SRC-1 0.2377 1 1
Toxoplasma gondii type I fatty acid synthase, putative 0.0061 0.0123 0.026
Brugia malayi jmjC domain containing protein 0.0222 0.0811 0.0743
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0951 0.3918 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi PHD-finger family protein 0.0177 0.0619 0.055
Echinococcus multilocularis neuropeptide FF receptor 2 0.0104 0.0306 0.0234
Echinococcus multilocularis signal transduction protein lnk realted 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus kinase suppressor of Ras 1 0.0951 0.3918 0.3874
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0951 0.3918 0.3874
Brugia malayi larval opioid receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus neuropeptide receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) STAT protein 0.1426 0.5944 0.5944
Trichomonas vaginalis TK family protein kinase 0.0951 0.3918 1
Echinococcus granulosus protein tyrosine kinase 0.0951 0.3918 0.3874
Mycobacterium ulcerans polyketide synthase 0.0057 0.0108 0.234
Brugia malayi bone morphogenetic protein type 1 receptor 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Toxoplasma gondii PHD-finger domain-containing protein 0.0543 0.2178 0.5533
Plasmodium falciparum tyrosine kinase-like protein 0.0951 0.3918 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1426 0.5944 0.5914
Trypanosoma cruzi protein kinase, putative 0.0951 0.3918 1
Onchocerca volvulus 0.2377 1 1
Onchocerca volvulus 0.2377 1 1
Schistosoma mansoni hypothetical protein 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus multilocularis serotonin receptor 0.0104 0.0306 0.0234
Schistosoma mansoni adenoreceptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0097 0.0274 0.0274
Brugia malayi putative neuropeptide receptor 0.0104 0.0306 0.0234
Echinococcus granulosus insulin receptor 0.0951 0.3918 0.3874
Echinococcus granulosus orexin receptor type 2 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Echinococcus granulosus tyrosine protein kinase Lyn 0.2377 1 1
Schistosoma mansoni tyrosine-protein kinase zap-70 0.1426 0.5944 0.5914
Onchocerca volvulus Neuropeptide F receptor homolog 0.0104 0.0306 0.0216
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0104 0.0306 0.0234
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis jumonji domain containing 1A 0.0376 0.1467 0.1404
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0951 0.3918 0.3874
Echinococcus granulosus tyrosine protein kinase Srms 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi neuropeptide F receptor 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Leishmania major protein kinase, putative 0.0951 0.3918 1
Loa Loa (eye worm) TK/CSK protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni biogenic amine (5HT) receptor 0.0104 0.0306 0.0234
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0171 0.059 0.1264
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0104 0.0306 0.0234
Schistosoma mansoni tensin 0.1426 0.5944 0.5914
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0104 0.0306 0.0234
Brugia malayi G-protein coupled receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Echinococcus granulosus signal transduction protein lnk realted 0.1426 0.5944 0.5914
Onchocerca volvulus 0.0104 0.0306 0.0216
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0104 0.0306 0.0234
Brugia malayi Tensin 0.1426 0.5944 0.5914
Echinococcus granulosus retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Plasmodium vivax hypothetical protein, conserved 0.0177 0.0619 0.0088
Echinococcus multilocularis SH2 motif 0.1426 0.5944 0.5914
Schistosoma mansoni jumonji domain containing protein 0.0376 0.1467 0.1404
Onchocerca volvulus 0.1426 0.5944 0.5907
Echinococcus multilocularis tyrosine protein kinase csk 0.0951 0.3918 0.3874
Onchocerca volvulus 0.1426 0.5944 0.5907
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0104 0.0306 0.0234
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Mycobacterium ulcerans Type I modular polyketide synthase 0.0057 0.0108 0.234
Mycobacterium ulcerans Type I modular polyketide synthase 0.0057 0.0108 0.234
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0104 0.0306 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0104 0.0306 0.0234
Onchocerca volvulus 0.2377 1 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1426 0.5944 0.5944
Schistosoma mansoni amine GPCR 0.0104 0.0306 0.0234
Echinococcus multilocularis natriuretic peptide receptor 1 0.0951 0.3918 0.3874
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Echinococcus multilocularis SH2 domain containing adapter protein F 0.1426 0.5944 0.5914
Echinococcus granulosus tensin C1 domain containing phosphatase 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0951 0.3918 0.3862
Schistosoma mansoni neuropeptide F-like receptor 0.0104 0.0306 0.0234
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.1426 0.5944 0.5914
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0061 0.0123 0.2769
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Schistosoma mansoni suppressor of cytokine signaling 0.1426 0.5944 0.5914
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.1426 0.5944 0.5907
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase HCK 0.0951 0.3918 0.3874
Loa Loa (eye worm) TK/EPH protein kinase 0.0951 0.3918 0.3918
Brugia malayi Protein kinase domain containing protein 0.2377 1 1
Echinococcus granulosus tyrosine kinase 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) RGC/RGC protein kinase 0.0951 0.3918 0.3918
Brugia malayi Serotonin receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0951 0.3918 0.3918
Echinococcus multilocularis tyrosine protein kinase Abl 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Brugia malayi SH2 domain containing protein 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Echinococcus granulosus somatostatin receptor 0.0104 0.0306 0.0234
Schistosoma mansoni histamine h1 receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Onchocerca volvulus 0.0104 0.0306 0.0216
Brugia malayi jmjC domain containing protein 0.0222 0.0811 0.0743
Loa Loa (eye worm) RhoGAP domain-containing protein 0.1426 0.5944 0.5944
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Echinococcus multilocularis N chimaerin 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi SH2 domain containing protein 0.1426 0.5944 0.5914
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi STAT protein, DNA binding domain containing protein 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein kinase shark 0.2377 1 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0104 0.0306 0.0234
Schistosoma mansoni biogenic amine receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis PHD finger protein rhinoceros 0.0543 0.2178 0.212
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0054 0.0092 0.0092
Onchocerca volvulus 0.0951 0.3918 0.3862
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi Bromodomain containing protein 0.0543 0.2178 0.212
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Brugia malayi G-protein coupled receptor 0.0104 0.0306 0.0234
Schistosoma mansoni opsin-like receptor 0.0104 0.0306 0.0234
Brugia malayi thymidylate synthase 0.0121 0.0379 0.0308
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Onchocerca volvulus 0.0951 0.3918 0.3862
Loa Loa (eye worm) hypothetical protein 0.0177 0.0619 0.0619
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0061 0.0123 0.2769
Brugia malayi Tyrosine-protein kinase abl-1 0.2377 1 1
Echinococcus multilocularis neuropeptide receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2377 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0951 0.3918 0.3874
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0951 0.3918 0.3874
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0177 0.0619 0.0088
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1426 0.5944 0.5914
Onchocerca volvulus 0.0121 0.0379 0.029
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus peptide allatostatin:somatostatin 0.0104 0.0306 0.0234
Echinococcus multilocularis g protein coupled receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0104 0.0306 0.0234
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0104 0.0306 0.0234
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0951 0.3918 1
Loa Loa (eye worm) G-protein coupled receptor 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0951 0.3918 1
Schistosoma mansoni hypothetical protein 0.0104 0.0306 0.0234
Schistosoma mansoni ephrin receptor 0.0951 0.3918 0.3874
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni protein phosphatase 2C 0.0222 0.0811 0.0743
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0951 0.3918 0.3918
Mycobacterium leprae Probable polyketide synthase Pks1 0.0061 0.0123 0.2769
Mycobacterium ulcerans Type I modular polyketide synthase 0.0057 0.0108 0.234
Schistosoma mansoni biogenic amine receptor 0.0104 0.0306 0.0234
Toxoplasma gondii PHD-finger domain-containing protein 0.0543 0.2178 0.5533
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0951 0.3918 0.3918
Onchocerca volvulus 0.2377 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Brugia malayi RhoGAP domain containing protein 0.1426 0.5944 0.5914
Plasmodium vivax hypothetical protein, conserved 0.0543 0.2178 0.477
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0104 0.0306 0.0234
Entamoeba histolytica SH2 domain containing protein 0.1426 0.5944 0.3331
Echinococcus granulosus tyrosine protein kinase Fps85D 0.2377 1 1
Echinococcus granulosus tyrosine protein kinase csk 0.0951 0.3918 0.3874
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0047 0.0063 0.1618
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.2377 1 1
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis transfer RNA-Thr 0.0951 0.3918 0.3874
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0104 0.0306 0.0216
Schistosoma mansoni growth hormone secretagogue receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) neuropeptide F receptor 0.0104 0.0306 0.0306
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Onchocerca volvulus 0.0104 0.0306 0.0216
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2377 1 1
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis fmrfamide receptor 0.0104 0.0306 0.0234
Schistosoma mansoni hypothetical protein 0.0177 0.0619 0.055
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0951 0.3918 0.3874
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0222 0.0811 0.1845
Schistosoma mansoni neuropeptide receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis heat shock protein 70 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Echinococcus granulosus tyrosine protein kinase Src42A 0.1426 0.5944 0.5914
Brugia malayi Protein kinase domain containing protein 0.2377 1 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1426 0.5944 0.5914
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine protein kinase 0.0951 0.3918 0.3874
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.2377 1 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0951 0.3918 0.3874
Echinococcus granulosus tachykinin peptides receptor 99D 0.0104 0.0306 0.0234
Echinococcus multilocularis peregrin 0.0543 0.2178 0.212
Echinococcus multilocularis tyrosine protein kinase Src42A 0.2377 1 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0177 0.0619 0.055
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Trichomonas vaginalis AGC family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Mycobacterium tuberculosis Hypothetical protein 0.0058 0.0109 0.2823
Plasmodium falciparum protein kinase, putative 0.0951 0.3918 1
Echinococcus granulosus serotonin receptor 0.0104 0.0306 0.0234
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0061 0.0123 0.2769
Echinococcus multilocularis lysine specific demethylase 6a 0.0222 0.0811 0.0743
Echinococcus granulosus neuropeptide Y receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) jmjC domain-containing protein 0.0222 0.0811 0.0811
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.2377 1 1
Echinococcus granulosus SH2 domain containing protein 7 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Schistosoma mansoni neuropeptide f receptor 76f 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Schistosoma mansoni suppressor of cytokine signaling 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Schistosoma mansoni protein tyrosine kinase 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0177 0.0619 0.0088
Echinococcus multilocularis jumonji domain containing protein 0.0756 0.3084 0.3033
Onchocerca volvulus 0.01 0.0289 0.0199
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.2377 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0951 0.3918 0.3874
Schistosoma mansoni protein kinase 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.2377 1 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0951 0.3918 0.3874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Echinococcus granulosus neuropeptides capa receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus peregrin 0.0543 0.2178 0.212
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Onchocerca volvulus 0.0104 0.0306 0.0216
Loa Loa (eye worm) TK/ALK protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni hypothetical protein 0.0104 0.0306 0.0234
Echinococcus multilocularis neuropeptides capa receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis integrin linked protein kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0951 0.3918 1
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Echinococcus multilocularis orexin receptor type 2 0.0104 0.0306 0.0234
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Toxoplasma gondii protein kinase domain-containing protein 0.0951 0.3918 1
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0951 0.3918 0.3874
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Brugia malayi hypothetical protein 0.0058 0.0109 0.0035
Echinococcus granulosus retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Loa Loa (eye worm) jmjC domain-containing protein 0.0376 0.1467 0.1467
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0049 0.0073 0.1373
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus 7tm_1 domain containing protein 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Plasmodium falciparum tyrosine kinase-like protein 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0951 0.3918 0.3874
Loa Loa (eye worm) melatonin receptor type 1A 0.0104 0.0306 0.0306
Echinococcus granulosus N chimaerin 0.1426 0.5944 0.5914
Echinococcus granulosus suppressor of cytokine signaling 6 0.1426 0.5944 0.5914
Loa Loa (eye worm) TYRA-2 protein 0.0104 0.0306 0.0306
Toxoplasma gondii STE kinase 0.0951 0.3918 1
Echinococcus multilocularis neuropeptide receptor A26 0.0104 0.0306 0.0234
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0951 0.3918 0.3874
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0222 0.0811 0.1845
Loa Loa (eye worm) TK/FAK protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) serine/threonine protein kinase 0.0951 0.3918 0.3918
Schistosoma mansoni tyrosine kinase 0.2377 1 1
Loa Loa (eye worm) fatty acid synthase 0.0057 0.0104 0.0104
Echinococcus granulosus expressed conserved protein 0.1426 0.5944 0.5914
Echinococcus granulosus neuropeptide receptor 0.0104 0.0306 0.0234
Schistosoma mansoni ephrin receptor 0.0951 0.3918 0.3874
Echinococcus granulosus raf serine:threonine protein kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis dro:myosuppressin receptor 0.0104 0.0306 0.0234
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2377 1 1
Plasmodium falciparum protein kinase, putative 0.0951 0.3918 1
Trypanosoma cruzi protein kinase, putative 0.0951 0.3918 1
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Echinococcus granulosus integrin linked protein kinase 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus g protein coupled receptor 0.0104 0.0306 0.0234
Onchocerca volvulus Fatty acid synthase homolog 0.0104 0.0304 0.0215
Onchocerca volvulus 0.0104 0.0306 0.0216
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Brugia malayi sulfakinin receptor protein 0.0104 0.0306 0.0234
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Loa Loa (eye worm) RGC/RGC protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2377 1 1
Brugia malayi tRNA modification GTPase TrmE family protein 0.1426 0.5944 0.5914
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Trichomonas vaginalis protein tyrosine kinase, putative 0.0951 0.3918 1
Echinococcus multilocularis protein KINase family member (kin 25) 0.0951 0.3918 0.3874
Mycobacterium ulcerans polyketide synthase 0.0061 0.0123 0.2769
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0951 0.3918 0.3874
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis tyrosine protein kinase shark 0.2377 1 1
Brugia malayi AF-10 protein 0.0177 0.0619 0.055
Schistosoma mansoni tyrosine kinase 0.2377 1 1
Onchocerca volvulus 0.0104 0.0306 0.0216
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.2377 1 1
Echinococcus granulosus neuropeptide Y receptor 0.0104 0.0306 0.0234
Brugia malayi Sex muscle abnormal protein 5 0.1426 0.5944 0.5914
Echinococcus multilocularis insulin receptor 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis protein kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0951 0.3918 0.3874
Echinococcus multilocularis tyrosine protein kinase Src64B 0.2377 1 1
Echinococcus granulosus lysine specific demethylase 5A 0.0704 0.2866 0.2814
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0104 0.0306 0.0234
Echinococcus granulosus SH2 motif 0.1426 0.5944 0.5914
Loa Loa (eye worm) TK protein kinase 0.0951 0.3918 0.3918
Echinococcus multilocularis receptor type guanylyl cyclase 0.0951 0.3918 0.3874
Schistosoma mansoni tensin-related 0.1426 0.5944 0.5914
Loa Loa (eye worm) TK protein kinase 0.2377 1 1
Entamoeba histolytica protein kinase, putative 0.1426 0.5944 0.3331
Brugia malayi Variant SH3 domain containing protein 0.1426 0.5944 0.5914
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0104 0.0306 0.0306
Entamoeba histolytica SH2-protein kinase domain containing protein 0.2377 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2377 1 1
Loa Loa (eye worm) SH2 domain-containing protein 0.1426 0.5944 0.5944
Brugia malayi follicle stimulating hormone receptor 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0951 0.3918 1
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1426 0.5944 0.5914
Onchocerca volvulus Alhambra homolog 0.0543 0.2178 0.2105
Brugia malayi GnHR receptor homolog 0.0104 0.0306 0.0234
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.1825 0.7646 0.7629
Loa Loa (eye worm) TK/FER protein kinase 0.2377 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase Srms 0.2377 1 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0104 0.0306 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Onchocerca volvulus 0.0951 0.3918 0.3862
Schistosoma mansoni myosin xvIII 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus c src tyrosine kinase 0.2377 1 1
Brugia malayi hypothetical protein 0.1426 0.5944 0.5914
Loa Loa (eye worm) TK/FER protein kinase 0.0951 0.3918 0.3918
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0104 0.0306 0.0306
Brugia malayi hypothetical protein 0.0104 0.0306 0.0234
Echinococcus multilocularis epidermal growth factor receptor 0.0951 0.3918 0.3874
Brugia malayi Variant SH3 domain containing protein 0.1426 0.5944 0.5914
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0061 0.0123 0.2769
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1426 0.5944 0.5944
Plasmodium falciparum protein kinase, putative 0.0951 0.3918 1
Echinococcus granulosus growth factor receptor bound protein 2 0.1426 0.5944 0.5914
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Brugia malayi RE15519p 0.0104 0.0306 0.0234
Echinococcus granulosus tyrosine protein kinase 0.0951 0.3918 0.3874
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Echinococcus granulosus biogenic amine 5HT receptor 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.2377 1 1
Echinococcus granulosus protein kinase 0.0951 0.3918 0.3874
Echinococcus granulosus neuropeptide receptor A26 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Loa Loa (eye worm) thymidylate synthase 0.0121 0.0379 0.0379
Schistosoma mansoni tyrosine kinase 0.2377 1 1
Onchocerca volvulus 0.0104 0.0306 0.0216
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0704 0.2866 0.2814
Onchocerca volvulus 0.0104 0.0306 0.0216
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Schistosoma mansoni tyrosine kinase 0.0951 0.3918 0.3874
Echinococcus multilocularis SH2 domain containing protein 7 0.1426 0.5944 0.5914
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0951 0.3918 0.3874
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0057 0.0108 0.0035
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0049 0.0073 0.1373
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0951 0.3918 0.3874
Schistosoma mansoni tyrosine kinase 0.2377 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0951 0.3918 0.3874
Echinococcus granulosus jumonji domain containing 1A 0.0376 0.1467 0.1404
Onchocerca volvulus 0.0951 0.3918 0.3862
Giardia lamblia Protein 21.1 0.0951 0.3918 1
Echinococcus granulosus SH2 motif 0.1426 0.5944 0.5914
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Echinococcus granulosus rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Loa Loa (eye worm) hypothetical protein 0.0951 0.3918 0.3918
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0057 0.0108 0.234
Echinococcus granulosus hypothetical protein 0.0104 0.0306 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0951 0.3918 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0104 0.0306 0.0234
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1426 0.5944 0.5914
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Echinococcus multilocularis fmrfamide receptor 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0951 0.3918 0.3874
Loa Loa (eye worm) hypothetical protein 0.1426 0.5944 0.5944
Brugia malayi Protein kinase domain containing protein 0.0951 0.3918 0.3874
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.1825 0.7646 0.7629
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2377 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0704 0.2866 0.2866
Trichomonas vaginalis TKL family protein kinase 0.0951 0.3918 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0104 0.0306 0.0234
Toxoplasma gondii PHD-finger domain-containing protein 0.0177 0.0619 0.1534
Toxoplasma gondii protein kinase 0.0951 0.3918 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.0306 0.0306
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0061 0.0123 0.3204
Echinococcus multilocularis activated cdc42 kinase 1 0.0951 0.3918 0.3874
Echinococcus granulosus tyrosine protein kinase ABL1 0.2377 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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