TDR Targets

Basic information

Technical information

TDR Targets ID: 1773445
Name: (2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino ]-3-(3H-imidazol-4-yl)propanamide
MW: 301.344 | Formula: C15H19N5O2
H donors: 4 H acceptors: 3 LogP: -0.27 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: O=C([C@H](Cc1ccccc1)N)N[C@H](C(=O)N)Cc1cnc[nH]1
InChi: 1S/C15H19N5O2/c16-12(6-10-4-2-1-3-5-10)15(22)20-13(14(17)21)7-11-8-18-9-19-11/h1-5,8-9,12-13H,6-7,16H2,(H2,17,21)(H,18,19)(H,20,22)/t12-,13-/m0/s1
InChiKey: FRFVPOGIWYVIRT-STQMWFEESA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(2S)-2-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-3-(3H-imidazol-4-yl)propanamide
(2S)-2-[[(2S)-2-amino-1-oxo-3-phenylpropyl]amino]-3-(3H-imidazol-4-yl)propanamide
(2S)-2-[[(2S)-2-amino-3-phenyl-propanoyl]amino]-3-(3H-imidazol-4-yl)propionamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus		0.0023	0.0084	0.008
Schistosoma mansoni	serine/threonine protein kinase	0.0822	0.3996	0.3993
Onchocerca volvulus	Huntingtin homolog	0.0119	0.0554	0.0549
Echinococcus multilocularis	N chimaerin	0.1227	0.5975	0.5973
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus granulosus	protein tyrosine kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Onchocerca volvulus		0.0822	0.3996	0.3993
Trypanosoma cruzi	protein kinase, putative	0.0822	0.3996	1
Schistosoma mansoni	tyrosine kinase	0.2049	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	N chimaerin	0.1227	0.5975	0.5973
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0019	0.0063	0.0059
Echinococcus multilocularis	activin receptor type	0.0822	0.3996	0.3993
Echinococcus multilocularis	tensin	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus granulosus	survival motor neuron protein 1	0.023	0.1095	0.1091
Leishmania major	protein kinase, putative	0.0822	0.3996	1
Loa Loa (eye worm)	SH2 domain-containing protein	0.1227	0.5975	0.5973
Brugia malayi	Muscleblind-like protein	0.0145	0.0681	0.0677
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0023	0.0084	0.008
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0189	0.0184
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.2049	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tensin	0.1227	0.5975	0.5973
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0822	0.3997	0.3994
Echinococcus multilocularis	insulin receptor	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.2049	1	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0822	0.3996	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosin kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	serine/threonine kinase, putative	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0017	0.0056	0.6421
Entamoeba histolytica	tyrosin kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3997	0.3994
Echinococcus granulosus	suppressor of cytokine signaling 6	0.1227	0.5975	0.5973
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.2049	1	1
Schistosoma mansoni	tyrosine kinase	0.2049	1	1
Echinococcus granulosus	signal transduction protein lnk realted	0.1227	0.5975	0.5973
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0189	0.0184
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	SH2 domain-containing protein	0.1227	0.5975	0.5973
Echinococcus granulosus	tyrosine kinase	0.2049	1	1
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0023	0.0084	1
Onchocerca volvulus		0.1227	0.5975	0.5973
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0822	0.3996	1
Schistosoma mansoni	tyrosine kinase	0.2049	1	1
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.0145	0.0681	0.0677
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	serine/threonine kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	NCK adaptor protein	0.1227	0.5975	0.5973
Schistosoma mansoni	SH2A	0.1227	0.5975	0.5973
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Brugia malayi	C-terminal src kinase protein 1	0.0822	0.3996	0.3993
Schistosoma mansoni	GTPase activating protein	0.1227	0.5975	0.5973
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.2049	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0822	0.3996	0.3993
Leishmania major	4-coumarate:coa ligase-like protein	0.0023	0.0084	0.0199
Schistosoma mansoni	growth factor receptor-bound protein	0.1227	0.5975	0.5973
Schistosoma mansoni	vav2	0.1227	0.5975	0.5973
Entamoeba histolytica	receptor protein kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0119	0.0554	0.0549
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0084	0.008
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.2049	1	1
Loa Loa (eye worm)	STAT protein	0.1227	0.5975	0.5973
Echinococcus granulosus	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Onchocerca volvulus	Tyrosine kinase homolog	0.0822	0.3996	0.3993
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0822	0.3996	0.3993
Echinococcus granulosus	expressed conserved protein	0.1227	0.5975	0.5973
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.2049	1	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.1227	0.5975	0.5973
Onchocerca volvulus		0.0822	0.3996	0.3993
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Entamoeba histolytica	hypothetical protein	0.0822	0.3997	0.3994
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Fyn	0.2049	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0019	0.0063	0.7511
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Onchocerca volvulus		0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.1227	0.5975	0.5973
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	serine/threonine kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Onchocerca volvulus		0.2049	1	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Onchocerca volvulus		0.2049	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0023	0.0084	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0023	0.0084	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/ALK protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	ankyrin repeat protein	0.0822	0.3996	0.3993
Onchocerca volvulus		0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase pr2	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0822	0.3996	0.3993
Mycobacterium ulcerans	DNA polymerase IV	0.0019	0.0063	0.7367
Brugia malayi	Protein kinase domain containing protein	0.2049	1	1
Echinococcus multilocularis	SH2 motif	0.1227	0.5975	0.5973
Echinococcus granulosus	activated cdc42 kinase 1	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0822	0.3996	0.3993
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	suppressor of cytokine signaling	0.1227	0.5975	0.5973
Echinococcus granulosus	tyrosine protein kinase Lyn	0.2049	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0017	0.0056	0.6617
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	hypothetical protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	activin receptor type	0.0822	0.3996	0.3993
Toxoplasma gondii	protein kinase	0.0822	0.3996	1
Brugia malayi	protein-tyrosine kinase	0.2049	1	1
Brugia malayi	RhoGAP domain containing protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.1227	0.5975	0.5973
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	SH2 domain containing protein 7	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	suppressor of cytokine signaling 7	0.1227	0.5975	0.5973
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0044	0.0189	0.0184
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0023	0.0084	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0822	0.3996	0.3993
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.1227	0.5975	0.5973
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.2049	1	1
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0019	0.0063	0.0059
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0056	0.0051
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	integrin linked protein kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	muscleblind protein 1	0.0145	0.0681	0.0677
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.0007	0.0005	0.0546
Onchocerca volvulus		0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Echinococcus granulosus	activated cdc42 kinase 1	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0822	0.3996	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0016	0.0051	0.6071
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0063	0.0059
Brugia malayi	hypothetical protein	0.2049	1	1
Schistosoma mansoni	protein tyrosine kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	epidermal growth factor receptor	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/ROR protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	shc transforming protein	0.1227	0.5975	0.5973
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.2049	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Schistosoma mansoni	suppressor of cytokine signaling	0.1227	0.5975	0.5973
Trypanosoma brucei	DNA polymerase kappa, putative	0.0013	0.0035	0.0076
Plasmodium falciparum	protein kinase, putative	0.0822	0.3996	1
Onchocerca volvulus		0.1227	0.5975	0.5973
Trypanosoma brucei	unspecified product	0.0013	0.0035	0.0076
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0822	0.3996	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.2049	1	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Brugia malayi	Tyrosine-protein kinase PR2	0.0822	0.3996	0.3993
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0822	0.3996	0.3993
Echinococcus granulosus	hypothetical protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	survival motor neuron protein 1	0.023	0.1095	0.1091
Echinococcus multilocularis	SHC transforming protein 3	0.1227	0.5975	0.5973
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.1227	0.5975	0.5973
Trypanosoma cruzi	protein kinase, putative	0.0822	0.3996	1
Schistosoma mansoni	hypothetical protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	serine/threonine protein kinase	0.0822	0.3996	0.3993
Onchocerca volvulus	Huntingtin homolog	0.0119	0.0554	0.0549
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.1227	0.5975	0.5973
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0023	0.0084	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus granulosus	dna polymerase eta	0.0019	0.0063	0.0059
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0189	0.0184
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0822	0.3996	1
Brugia malayi	Raf kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosin kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3997	0.3994
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	FL cytokine receptor	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Probable peptide synthetase Nrp (peptide synthase)	0.0007	0.0005	0.0546
Onchocerca volvulus		0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/INSR protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	growth factor receptor bound protein 2	0.1227	0.5975	0.5973
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Echinococcus granulosus	insulin receptor	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0056	0.0051
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0822	0.3996	0.3993
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0016	0.0051	0.6071
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.2049	1	1
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Brugia malayi	hypothetical protein	0.023	0.1095	0.1091
Onchocerca volvulus		0.1227	0.5975	0.5973
Entamoeba histolytica	receptor protein kinase, putative	0.0822	0.3996	0.3993
Echinococcus granulosus	epidermal growth factor receptor	0.0822	0.3996	0.3993
Brugia malayi	Variant SH3 domain containing protein	0.1227	0.5975	0.5973
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.1227	0.5975	0.5973
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0016	0.0051	0.6071
Echinococcus multilocularis	tyrosine protein kinase	0.0822	0.3996	0.3993
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0084	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0189	0.0184
Echinococcus multilocularis	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0019	0.0063	0.0059
Leishmania major	4-coumarate:coa ligase-like protein	0.0023	0.0084	0.0199
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	acyl-coA synthetase, putative	0.0023	0.0084	0.008
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.1227	0.5975	0.5973
Mycobacterium tuberculosis	P-hydroxybenzoyl-AMP ligase FadD22	0.0007	0.0005	0.0546
Echinococcus multilocularis	c src tyrosine kinase	0.2049	1	1
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Leishmania major	hypothetical protein, conserved	0.0822	0.3996	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0084	0.008
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	epidermal growth factor receptor	0.0822	0.3996	0.3993
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0822	0.3996	0.3993
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.1227	0.5975	0.5973
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase eta, putative	0.0019	0.0063	0.0147
Entamoeba histolytica	tyrosin kinase, putative	0.0822	0.3996	0.3993
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0084	1
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	adapter molecule crk	0.1227	0.5975	0.5973
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/Met protein kinase	0.0822	0.3996	0.3993
Trypanosoma brucei	unspecified product	0.0013	0.0035	0.0076
Echinococcus granulosus	raf serine:threonine protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	STE family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2049	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Echinococcus multilocularis	heat shock protein 70	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	ImpB/MucB/SamB family protein	0.0019	0.0063	0.0059
Onchocerca volvulus		0.0047	0.0201	0.0196
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/DDR protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0822	0.3996	0.3993
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0019	0.0063	0.0059
Echinococcus granulosus	muscleblind protein	0.0145	0.0681	0.0677
Mycobacterium tuberculosis	Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Giardia lamblia	Kinase, NEK	0.0822	0.3996	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Brugia malayi	Variant SH3 domain containing protein	0.1227	0.5975	0.5973
Echinococcus multilocularis	protein kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.1227	0.5975	0.5973
Brugia malayi	Sex muscle abnormal protein 5	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	serine/threonine protein kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.1227	0.5975	0.5973
Brugia malayi	hypothetical protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0019	0.0063	0.0059
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0822	0.3996	0.3993
Schistosoma mansoni	nck2/grb4	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.1227	0.5975	0.5973
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0084	0.008
Echinococcus multilocularis	dna polymerase eta	0.0019	0.0063	0.0059
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Schistosoma mansoni	hypothetical protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	tensin	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.2049	1	1
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	serine/threonine kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Srms	0.2049	1	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Brugia malayi	Receptor family ligand binding region containing protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2049	1	1
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0822	0.3996	0.3993
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0044	0.0189	0.0184
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0822	0.3996	1
Onchocerca volvulus		0.1227	0.5975	0.5973
Loa Loa (eye worm)	hypothetical protein	0.0145	0.0681	0.0677
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	integrin linked protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.1227	0.5975	0.5973
Echinococcus granulosus	tyrosine protein kinase Src42A	0.1227	0.5975	0.5973
Entamoeba histolytica	protein kinase, putative	0.0822	0.3997	0.3994
Trypanosoma brucei	Pseudokinase, putative	0.0822	0.3996	1
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Brugia malayi	Variant SH3 domain containing protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase kappa, putative	0.0013	0.0035	0.0076
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	serine/threonine protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0822	0.3996	1
Brugia malayi	tRNA modification GTPase TrmE family protein	0.1227	0.5975	0.5973
Echinococcus multilocularis	SH2 motif	0.1227	0.5975	0.5973
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Onchocerca volvulus		0.1227	0.5975	0.5973
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	TK/EPH protein kinase	0.0822	0.3996	0.3993
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.2049	1	1
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.1227	0.5975	0.5973
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.023	0.1095	0.1091
Brugia malayi	Guanylyl cyclase protein 23	0.0822	0.3996	0.3993
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0822	0.3996	0.3993
Brugia malayi	cytokine inducible SH2-containing protein 5	0.1227	0.5975	0.5973
Brugia malayi	Protein kinase domain containing protein	0.2049	1	1
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0056	0.0051
Loa Loa (eye worm)	TK/CSK protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	ankyrin repeat protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	SHC transforming protein 3	0.1227	0.5975	0.5973
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Schistosoma mansoni	hypothetical protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	growth factor receptor-bound protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0019	0.0063	0.0147
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0084	0.008
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0189	0.0184
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	hypothetical protein, conserved	0.0822	0.3996	0.3993
Schistosoma mansoni	DNA polymerase eta	0.0019	0.0063	0.0059
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.2049	1	1
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.2049	1	1
Brugia malayi	integrin-linked kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine protein kinase	0.0822	0.3996	0.3993
Mycobacterium ulcerans	hypothetical protein	0.0023	0.0084	1
Echinococcus multilocularis	growth factor receptor bound protein 2	0.1227	0.5975	0.5973
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Onchocerca volvulus		0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Schistosoma mansoni	serine/threonine protein kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.2049	1	1
Echinococcus granulosus	tyrosine protein kinase Src64B	0.2049	1	1
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0189	0.0184
Trypanosoma brucei	protein kinase, putative	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0822	0.3996	1
Brugia malayi	STAT protein, DNA binding domain containing protein	0.1227	0.5975	0.5973
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Schistosoma mansoni	tyrosine kinase	0.2049	1	1
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.1227	0.5975	0.5973
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	AGC family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	c src tyrosine kinase	0.2049	1	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	dna polymerase kappa	0.0019	0.0063	0.0059
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Leishmania major	DNA polymerase eta, putative	0.0019	0.0063	0.0147
Toxoplasma gondii	STE kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	SH2 domain containing protein	0.1227	0.5975	0.5973
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0822	0.3996	0.3993
Brugia malayi	Furin-like cysteine rich region family protein	0.0822	0.3996	0.3993
Echinococcus multilocularis		0.1227	0.5975	0.5973
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0056	0.0051
Echinococcus multilocularis	tyrosine protein kinase shark	0.2049	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	tensin	0.1227	0.5975	0.5973
Schistosoma mansoni	signal transduction protein lnk-related	0.1227	0.5975	0.5973
Onchocerca volvulus		0.0822	0.3996	0.3993
Trichomonas vaginalis	TK family protein kinase	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Plasmodium falciparum	protein kinase, putative	0.0822	0.3996	1
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0822	0.3996	0.3993
Brugia malayi	Tyrosine-protein kinase abl-1	0.2049	1	1
Onchocerca volvulus		0.2049	1	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.1227	0.5975	0.5973
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0016	0.0051	0.6071
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Giardia lamblia	Kinase	0.0822	0.3996	1
Echinococcus granulosus	tyrosine protein kinase Srms	0.2049	1	1
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	serine/threonine kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.1227	0.5975	0.5973
Trypanosoma brucei	DNA polymerase IV, putative	0.0019	0.0063	0.0147
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus granulosus	kinase suppressor of Ras 1	0.0822	0.3996	0.3993
Brugia malayi	Tensin	0.1227	0.5975	0.5973
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0019	0.0063	0.7511
Echinococcus granulosus	tyrosine protein kinase Blk	0.2049	1	1
Mycobacterium tuberculosis	Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase)	0.0007	0.0005	0.0546
Schistosoma mansoni	tensin	0.1227	0.5975	0.5973
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Blk	0.2049	1	1
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase ABL1	0.2049	1	1
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Brugia malayi	ephrin receptor 1 precursor	0.0822	0.3996	0.3993
Schistosoma mansoni	tensin	0.1227	0.5975	0.5973
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine kinase	0.2049	1	1
Schistosoma mansoni	survival motor neuron protein	0.0047	0.0201	0.0196
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Plasmodium falciparum	acyl-CoA synthetase	0.0017	0.0056	0.0128
Echinococcus multilocularis	transfer RNA-Thr	0.0822	0.3996	0.3993
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase HCK	0.0822	0.3996	0.3993
Entamoeba histolytica	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.2049	1	1
Echinococcus granulosus	tyrosine protein kinase shark	0.2049	1	1
Trypanosoma brucei	DNA polymerase IV, putative	0.0019	0.0063	0.0147
Entamoeba histolytica	protein kinase domain containing protein	0.0822	0.3996	0.3993
Leishmania major	protein kinase, putative	0.0822	0.3996	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0189	0.0184
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0084	0.008
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.1227	0.5975	0.5973
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0822	0.3996	0.3993
Giardia lamblia	Kinase, NEK	0.0822	0.3996	1
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2049	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	tyrosine kinase	0.2049	1	1
Plasmodium vivax	acyl-CoA synthetase, putative	0.0017	0.0056	0.0128
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.2049	1	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2049	1	1
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.1227	0.5975	0.5973
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.2049	1	1
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0822	0.3996	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	tyrosine protein kinase Abl	0.2049	1	1
Echinococcus multilocularis	SH2 domain containing protein 7	0.1227	0.5975	0.5973
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Echinococcus granulosus	NCK adaptor protein	0.1227	0.5975	0.5973
Schistosoma mansoni	tensin-related	0.1227	0.5975	0.5973
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.2049	1	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0013	0.0035	0.0076
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0047	0.0201	0.0196
Schistosoma mansoni	ephrin receptor	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	tyrosine kinase	0.2049	1	1
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.2049	1	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0822	0.3996	0.3993
Leishmania major	4-coumarate:coa ligase-like protein	0.0023	0.0084	0.0199
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0023	0.0084	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus granulosus	SH2 motif	0.1227	0.5975	0.5973
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	ephrin receptor	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Fyn	0.2049	1	1
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Brugia malayi	Variant SH3 domain containing protein	0.1227	0.5975	0.5973
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0822	0.3996	0.3993
Echinococcus granulosus	ephrin type A receptor 4 A	0.0822	0.3996	0.3993
Onchocerca volvulus		0.2049	1	1
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.1227	0.5975	0.5973
Echinococcus granulosus	natriuretic peptide receptor 1	0.0822	0.3996	0.3993
Plasmodium falciparum	tyrosine kinase-like protein	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Loa Loa (eye worm)	SH2 domain-containing protein	0.1227	0.5975	0.5973
Brugia malayi	hypothetical protein	0.0119	0.0554	0.0549
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Mycobacterium tuberculosis	Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	0.0007	0.0005	0.0546
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Echinococcus granulosus	receptor type guanylyl cyclase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0017	0.0056	0.0051
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	cysteine surface protein, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	signal transduction protein lnk realted	0.1227	0.5975	0.5973
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0822	0.3996	0.3993
Mycobacterium tuberculosis	Peptide synthetase MbtF (peptide synthase)	0.0007	0.0005	0.0546
Plasmodium vivax	protein kinase, putative	0.0822	0.3996	1
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0023	0.0084	0.008
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/RYK protein kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/FER protein kinase	0.2049	1	1
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Schistosoma mansoni	tensin-related	0.1227	0.5975	0.5973
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0007	0.0005	0.0546
Giardia lamblia	Protein 21.1	0.0822	0.3996	1
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0023	0.0084	1
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Fyn	0.2049	1	1
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.1227	0.5975	0.5973
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0822	0.3996	0.3993
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Echinococcus granulosus	SH2 motif	0.1227	0.5975	0.5973
Mycobacterium ulcerans	DNA polymerase IV	0.0019	0.0063	0.7367
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0084	0.008
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine kinase	0.0822	0.3996	0.3993
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0822	0.3996	1
Trichomonas vaginalis	CAMK family protein kinase	0.0822	0.3996	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Onchocerca volvulus		0.2049	1	1
Echinococcus granulosus	dna polymerase kappa	0.0019	0.0063	0.0059
Loa Loa (eye worm)	SRC-1	0.2049	1	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0023	0.0084	1
Toxoplasma gondii	protein kinase domain-containing protein	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Echinococcus granulosus	tyrosine protein kinase csk	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Schistosoma mansoni	protein kinase	0.0822	0.3996	0.3993
Onchocerca volvulus		0.2049	1	1
Mycobacterium tuberculosis	Peptide synthetase MbtE (peptide synthase)	0.0007	0.0005	0.0546
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0822	0.3996	0.3993
Brugia malayi	ImpB/MucB/SamB family protein	0.0019	0.0063	0.0059
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Echinococcus multilocularis	protein tyrosine kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0822	0.3996	0.3993
Onchocerca volvulus		0.0822	0.3996	0.3993
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0822	0.3996	0.3993
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0017	0.0056	0.5
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Trypanosoma cruzi	DNA polymerase eta, putative	0.0019	0.0063	0.0147
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.2049	1	1
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0822	0.3996	0.3993
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.2049	1	1
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0822	0.3996	0.3993
Echinococcus multilocularis	activated cdc42 kinase 1	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	hypothetical protein	0.0119	0.0554	0.0549
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	tyrosine protein kinase Src42A	0.2049	1	1
Schistosoma mansoni	serine/threonine RGC	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0822	0.3996	0.3993
Trichomonas vaginalis	conserved hypothetical protein	0.0822	0.3996	1
Entamoeba histolytica	tyrosine kinase, putative	0.0822	0.3996	0.3993
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0822	0.3996	0.3993
Echinococcus granulosus	protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	protein kinase atn1, putative	0.0822	0.3996	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0822	0.3996	1
Plasmodium falciparum	protein kinase, putative	0.0822	0.3996	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.1227	0.5975	0.5973
Trichomonas vaginalis	DNA polymerase eta, putative	0.0019	0.0063	0.0147
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0822	0.3996	1
Onchocerca volvulus		0.1227	0.5975	0.5973
Brugia malayi	hypothetical protein	0.0822	0.3996	0.3993
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Leishmania major	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0019	0.0063	0.0059
Echinococcus multilocularis	SH2 motif	0.1227	0.5975	0.5973
Entamoeba histolytica	serine/threonine kinase, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0822	0.3996	1
Brugia malayi	Protein kinase domain containing protein	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	hypothetical protein	0.1227	0.5975	0.5973
Echinococcus granulosus	SH2 domain containing adapter protein F	0.1227	0.5975	0.5973
Trypanosoma brucei	unspecified product	0.0019	0.0063	0.0147
Echinococcus multilocularis	epidermal growth factor receptor	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK protein kinase	0.2049	1	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.2049	1	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0822	0.3996	0.3993
Mycobacterium ulcerans	acyl-CoA synthetase	0.0023	0.0084	1
Brugia malayi	SRC-1	0.2049	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	tyrosine kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Schistosoma mansoni	hypothetical protein	0.0047	0.0201	0.0196
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.1227	0.5975	0.5973
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK protein kinase	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Loa Loa (eye worm)	hypothetical protein	0.0822	0.3996	0.3993
Brugia malayi	SH2 domain containing protein	0.1227	0.5975	0.5973
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0019	0.0063	0.0147
Echinococcus multilocularis	muscleblind protein	0.0145	0.0681	0.0677
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0822	0.3996	0.3993
Loa Loa (eye worm)	TK/ACK protein kinase	0.0822	0.3996	0.3993
Trichomonas vaginalis	TKL family protein kinase	0.0822	0.3996	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0822	0.3996	0.3993
Entamoeba histolytica	protein kinase, putative	0.0822	0.3996	0.3993
Trypanosoma brucei	DNA polymerase IV, putative	0.0019	0.0063	0.0147
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.1227	0.5975	0.5973

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2408872

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1773445