Detailed information for compound 1773446

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 301.344 | Formula: C15H19N5O2
  • H donors: 4 H acceptors: 3 LogP: -0.27 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C([C@H](Cc1ccccc1)N)N[C@@H](C(=O)N)Cc1cnc[nH]1
  • InChi: 1S/C15H19N5O2/c16-12(6-10-4-2-1-3-5-10)15(22)20-13(14(17)21)7-11-8-18-9-19-11/h1-5,8-9,12-13H,6-7,16H2,(H2,17,21)(H,18,19)(H,20,22)/t12-,13+/m0/s1
  • InChiKey: FRFVPOGIWYVIRT-QWHCGFSZSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0005 0.0546
Onchocerca volvulus 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0681 0.0677
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0822 0.3996 1
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1227 0.5975 0.5973
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus granulosus activated cdc42 kinase 1 0.0822 0.3996 0.3993
Schistosoma mansoni protein tyrosine kinase 0.0822 0.3996 0.3993
Brugia malayi hypothetical protein 0.2049 1 1
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0019 0.0063 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0051 0.6071
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2049 1 1
Schistosoma mansoni suppressor of cytokine signaling 0.1227 0.5975 0.5973
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/ROR protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni shc transforming protein 0.1227 0.5975 0.5973
Echinococcus granulosus epidermal growth factor receptor 0.0822 0.3996 0.3993
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus hypothetical protein 0.1227 0.5975 0.5973
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0822 0.3996 1
Loa Loa (eye worm) TK/ABL protein kinase 0.2049 1 1
Brugia malayi Tyrosine-protein kinase PR2 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Trypanosoma brucei unspecified product 0.0013 0.0035 0.0076
Onchocerca volvulus 0.1227 0.5975 0.5973
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0035 0.0076
Plasmodium falciparum protein kinase, putative 0.0822 0.3996 1
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.1227 0.5975 0.5973
Echinococcus multilocularis SHC transforming protein 3 0.1227 0.5975 0.5973
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1095 0.1091
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0084 1
Onchocerca volvulus Huntingtin homolog 0.0119 0.0554 0.0549
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.1227 0.5975 0.5973
Loa Loa (eye worm) serine/threonine protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni hypothetical protein 0.0822 0.3996 0.3993
Trypanosoma cruzi protein kinase, putative 0.0822 0.3996 1
Echinococcus granulosus dna polymerase eta 0.0019 0.0063 0.0059
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Echinococcus multilocularis tyrosine protein kinase csk 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosin kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0822 0.3996 1
Brugia malayi Raf kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0189 0.0184
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Onchocerca volvulus 0.0822 0.3996 0.3993
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0005 0.0546
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis FL cytokine receptor 0.0822 0.3996 0.3993
Entamoeba histolytica hypothetical protein 0.0822 0.3997 0.3994
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0051
Echinococcus granulosus retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Echinococcus granulosus insulin receptor 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/INSR protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus growth factor receptor bound protein 2 0.1227 0.5975 0.5973
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0051 0.6071
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis raf serine:threonine protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0822 0.3996 0.3993
Brugia malayi hypothetical protein 0.023 0.1095 0.1091
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.2049 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis SH2 domain containing adapter protein F 0.1227 0.5975 0.5973
Entamoeba histolytica receptor protein kinase, putative 0.0822 0.3996 0.3993
Echinococcus granulosus epidermal growth factor receptor 0.0822 0.3996 0.3993
Onchocerca volvulus 0.1227 0.5975 0.5973
Brugia malayi Variant SH3 domain containing protein 0.1227 0.5975 0.5973
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0051 0.6071
Echinococcus multilocularis tyrosine protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1227 0.5975 0.5973
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0084 0.008
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0063 0.0059
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0084 0.0199
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0084 1
Echinococcus multilocularis tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0189 0.0184
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Leishmania major hypothetical protein, conserved 0.0822 0.3996 1
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0005 0.0546
Echinococcus multilocularis c src tyrosine kinase 0.2049 1 1
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0023 0.0084 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase csk 0.0822 0.3996 0.3993
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.1227 0.5975 0.5973
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0822 0.3996 0.3993
Echinococcus multilocularis epidermal growth factor receptor 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Schistosoma mansoni adapter molecule crk 0.1227 0.5975 0.5973
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0084 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0822 0.3996 0.3993
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0063 0.0147
Entamoeba histolytica tyrosin kinase, putative 0.0822 0.3996 0.3993
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Loa Loa (eye worm) TK/Met protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trypanosoma brucei unspecified product 0.0013 0.0035 0.0076
Trichomonas vaginalis STE family protein kinase 0.0822 0.3996 1
Echinococcus granulosus raf serine:threonine protein kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2049 1 1
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Onchocerca volvulus 0.0047 0.0201 0.0196
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0063 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus multilocularis heat shock protein 70 0.0822 0.3996 0.3993
Loa Loa (eye worm) RGC/RGC protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus muscleblind protein 0.0145 0.0681 0.0677
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0063 0.0059
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0546
Giardia lamblia Kinase, NEK 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) TK/DDR protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0822 0.3996 0.3993
Brugia malayi Sex muscle abnormal protein 5 0.1227 0.5975 0.5973
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.1227 0.5975 0.5973
Echinococcus multilocularis protein kinase 0.0822 0.3996 0.3993
Brugia malayi Variant SH3 domain containing protein 0.1227 0.5975 0.5973
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0063 0.0059
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis suppressor of cytokine signaling 6 0.1227 0.5975 0.5973
Brugia malayi hypothetical protein 0.0822 0.3996 0.3993
Schistosoma mansoni serine/threonine protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0084 0.008
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1227 0.5975 0.5973
Echinococcus multilocularis dna polymerase eta 0.0019 0.0063 0.0059
Echinococcus granulosus fibroblast growth factor receptor 4 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni nck2/grb4 0.1227 0.5975 0.5973
Echinococcus multilocularis tyrosine protein kinase Src64B 0.2049 1 1
Echinococcus granulosus tensin 0.1227 0.5975 0.5973
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni hypothetical protein 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0822 0.3996 0.3993
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Srms 0.2049 1 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Entamoeba histolytica serine/threonine kinase, putative 0.0822 0.3996 0.3993
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Brugia malayi Receptor family ligand binding region containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0822 0.3996 1
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase HCK 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0822 0.3996 0.3993
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.0189 0.0184
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2049 1 1
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus protein tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni serine/threonine protein kinase 0.0822 0.3996 0.3993
Onchocerca volvulus Huntingtin homolog 0.0119 0.0554 0.0549
Echinococcus multilocularis N chimaerin 0.1227 0.5975 0.5973
Onchocerca volvulus 0.0023 0.0084 0.008
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni tyrosine kinase 0.2049 1 1
Trypanosoma cruzi protein kinase, putative 0.0822 0.3996 1
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Onchocerca volvulus 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Echinococcus multilocularis activin receptor type 0.0822 0.3996 0.3993
Echinococcus granulosus N chimaerin 0.1227 0.5975 0.5973
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0063 0.0059
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1095 0.1091
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus multilocularis tensin 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0084 0.008
Brugia malayi Muscleblind-like protein 0.0145 0.0681 0.0677
Leishmania major protein kinase, putative 0.0822 0.3996 1
Loa Loa (eye worm) SH2 domain-containing protein 0.1227 0.5975 0.5973
Echinococcus multilocularis tensin 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.2049 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.0189 0.0184
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0822 0.3997 0.3994
Brugia malayi SH2 domain containing protein 0.2049 1 1
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis insulin receptor 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica serine/threonine kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosin kinase, putative 0.0822 0.3996 0.3993
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0056 0.6421
Entamoeba histolytica tyrosin kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0822 0.3996 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus suppressor of cytokine signaling 6 0.1227 0.5975 0.5973
Entamoeba histolytica hypothetical protein 0.0822 0.3997 0.3994
Echinococcus granulosus tyrosine kinase 0.2049 1 1
Loa Loa (eye worm) SH2 domain-containing protein 0.1227 0.5975 0.5973
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Echinococcus granulosus tyrosine protein kinase Btk29A 0.2049 1 1
Echinococcus granulosus signal transduction protein lnk realted 0.1227 0.5975 0.5973
Schistosoma mansoni tyrosine kinase 0.2049 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0189 0.0184
Echinococcus granulosus retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Onchocerca volvulus 0.1227 0.5975 0.5973
Trichomonas vaginalis protein tyrosine kinase, putative 0.0822 0.3996 1
Schistosoma mansoni tyrosine kinase 0.2049 1 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0084 1
Entamoeba histolytica serine/threonine kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0145 0.0681 0.0677
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni SH2A 0.1227 0.5975 0.5973
Echinococcus multilocularis NCK adaptor protein 0.1227 0.5975 0.5973
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.2049 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Brugia malayi C-terminal src kinase protein 1 0.0822 0.3996 0.3993
Schistosoma mansoni GTPase activating protein 0.1227 0.5975 0.5973
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0822 0.3996 0.3993
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0084 0.008
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0119 0.0554 0.0549
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica receptor protein kinase, putative 0.0822 0.3996 0.3993
Schistosoma mansoni growth factor receptor-bound protein 0.1227 0.5975 0.5973
Schistosoma mansoni vav2 0.1227 0.5975 0.5973
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0084 0.0199
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Onchocerca volvulus Tyrosine kinase homolog 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase csk 0.0822 0.3996 0.3993
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0822 0.3996 0.3993
Echinococcus granulosus expressed conserved protein 0.1227 0.5975 0.5973
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.2049 1 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) STAT protein 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase Fps85D 0.2049 1 1
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0063 0.7511
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase Fyn 0.2049 1 1
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Entamoeba histolytica hypothetical protein 0.0822 0.3997 0.3994
Onchocerca volvulus 0.0822 0.3996 0.3993
Echinococcus multilocularis receptor type guanylyl cyclase 0.0822 0.3996 0.3993
Entamoeba histolytica serine/threonine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Onchocerca volvulus 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.1227 0.5975 0.5973
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Plasmodium falciparum tyrosine kinase-like protein 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Onchocerca volvulus 0.2049 1 1
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/ALK protein kinase 0.0822 0.3996 0.3993
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0084 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0084 1
Onchocerca volvulus 0.2049 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Brugia malayi Protein kinase domain containing protein 0.2049 1 1
Echinococcus multilocularis SH2 motif 0.1227 0.5975 0.5973
Echinococcus granulosus activated cdc42 kinase 1 0.0822 0.3996 0.3993
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0063 0.7367
Echinococcus granulosus tyrosine protein kinase pr2 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Onchocerca volvulus 0.0822 0.3996 0.3993
Entamoeba histolytica ankyrin repeat protein 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/EGFR protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase Lyn 0.2049 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis natriuretic peptide receptor 1 0.0822 0.3996 0.3993
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0822 0.3996 0.3993
Schistosoma mansoni suppressor of cytokine signaling 0.1227 0.5975 0.5973
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0822 0.3996 0.3993
Brugia malayi hypothetical protein 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0056 0.6617
Brugia malayi RhoGAP domain containing protein 0.1227 0.5975 0.5973
Toxoplasma gondii protein kinase 0.0822 0.3996 1
Brugia malayi protein-tyrosine kinase 0.2049 1 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus activin receptor type 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.1227 0.5975 0.5973
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1227 0.5975 0.5973
Echinococcus granulosus SH2 domain containing protein 7 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.0189 0.0184
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0084 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1227 0.5975 0.5973
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Brugia malayi Immunoglobulin I-set domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica SH2-protein kinase domain containing protein 0.2049 1 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0063 0.0059
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis integrin linked protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0035 0.0076
Loa Loa (eye worm) hypothetical protein 0.2049 1 1
Schistosoma mansoni tensin-related 0.1227 0.5975 0.5973
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0822 0.3996 1
Schistosoma mansoni tyrosine kinase 0.2049 1 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0201 0.0196
Schistosoma mansoni ephrin receptor 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus SH2 motif 0.1227 0.5975 0.5973
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0084 1
Loa Loa (eye worm) protein kinase domain-containing protein 0.0822 0.3996 0.3993
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0084 0.0199
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.2049 1 1
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0822 0.3996 0.3993
Brugia malayi Variant SH3 domain containing protein 0.1227 0.5975 0.5973
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase Fyn 0.2049 1 1
Echinococcus multilocularis tyrosine protein kinase csk 0.0822 0.3996 0.3993
Schistosoma mansoni ephrin receptor 0.0822 0.3996 0.3993
Onchocerca volvulus 0.2049 1 1
Echinococcus granulosus ephrin type A receptor 4 A 0.0822 0.3996 0.3993
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1227 0.5975 0.5973
Brugia malayi hypothetical protein 0.0119 0.0554 0.0549
Loa Loa (eye worm) SH2 domain-containing protein 0.1227 0.5975 0.5973
Echinococcus multilocularis tyrosine protein kinase csk 0.0822 0.3996 0.3993
Echinococcus granulosus natriuretic peptide receptor 1 0.0822 0.3996 0.3993
Plasmodium falciparum tyrosine kinase-like protein 0.0822 0.3996 1
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Echinococcus granulosus receptor type guanylyl cyclase 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0546
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0005 0.0546
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0005 0.0546
Plasmodium vivax protein kinase, putative 0.0822 0.3996 1
Echinococcus multilocularis signal transduction protein lnk realted 0.1227 0.5975 0.5973
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica cysteine surface protein, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0051
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0822 0.3996 0.3993
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0084 0.008
Loa Loa (eye worm) RhoGAP domain-containing protein 0.1227 0.5975 0.5973
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/RYK protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Giardia lamblia Protein 21.1 0.0822 0.3996 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0546
Schistosoma mansoni tensin-related 0.1227 0.5975 0.5973
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0084 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0063 0.7367
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0023 0.0084 0.008
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus granulosus SH2 motif 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase Fyn 0.2049 1 1
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1227 0.5975 0.5973
Trichomonas vaginalis CAMK family protein kinase 0.0822 0.3996 1
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trypanosoma brucei Flagellum attachment zone protein 20 0.0822 0.3996 1
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine kinase 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Toxoplasma gondii protein kinase domain-containing protein 0.0822 0.3996 1
Loa Loa (eye worm) SRC-1 0.2049 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0084 1
Echinococcus granulosus dna polymerase kappa 0.0019 0.0063 0.0059
Onchocerca volvulus 0.2049 1 1
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0822 0.3996 0.3993
Onchocerca volvulus 0.2049 1 1
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0005 0.0546
Echinococcus granulosus tyrosine protein kinase csk 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis protein tyrosine kinase 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0063 0.0059
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.2049 1 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0063 0.0147
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0822 0.3996 0.3993
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0056 0.5
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0822 0.3996 0.3993
Onchocerca volvulus 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni serine/threonine RGC 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase Src42A 0.2049 1 1
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0119 0.0554 0.0549
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Loa Loa (eye worm) RGC/RGC protein kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis activated cdc42 kinase 1 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase pr2 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Fgr 0.2049 1 1
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine-protein kinase zap-70 0.1227 0.5975 0.5973
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0822 0.3996 0.3993
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0822 0.3996 1
Trichomonas vaginalis protein kinase atn1, putative 0.0822 0.3996 1
Echinococcus granulosus protein kinase 0.0822 0.3996 0.3993
Plasmodium falciparum protein kinase, putative 0.0822 0.3996 1
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0822 0.3996 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0063 0.0147
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1227 0.5975 0.5973
Leishmania major DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Onchocerca volvulus 0.1227 0.5975 0.5973
Brugia malayi hypothetical protein 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Plasmodium vivax tyrosine kinase-like protein, putative 0.0822 0.3996 1
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Entamoeba histolytica serine/threonine kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0063 0.0059
Echinococcus multilocularis SH2 motif 0.1227 0.5975 0.5973
Echinococcus multilocularis epidermal growth factor receptor 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.2049 1 1
Echinococcus granulosus SH2 domain containing adapter protein F 0.1227 0.5975 0.5973
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Trypanosoma brucei unspecified product 0.0019 0.0063 0.0147
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) TK/FER protein kinase 0.0822 0.3996 0.3993
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0084 1
Brugia malayi SRC-1 0.2049 1 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis suppressor of cytokine signaling 7 0.1227 0.5975 0.5973
Schistosoma mansoni hypothetical protein 0.0047 0.0201 0.0196
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0063 0.0147
Echinococcus multilocularis muscleblind protein 0.0145 0.0681 0.0677
Loa Loa (eye worm) TK/ACK protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0822 0.3996 0.3993
Brugia malayi SH2 domain containing protein 0.1227 0.5975 0.5973
Loa Loa (eye worm) variant SH3 domain-containing protein 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0063 0.0147
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Onchocerca volvulus 0.1227 0.5975 0.5973
Loa Loa (eye worm) hypothetical protein 0.0145 0.0681 0.0677
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase Src42A 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase, putative 0.0822 0.3997 0.3994
Echinococcus granulosus integrin linked protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Trypanosoma brucei Pseudokinase, putative 0.0822 0.3996 1
Brugia malayi tRNA modification GTPase TrmE family protein 0.1227 0.5975 0.5973
Echinococcus multilocularis SH2 motif 0.1227 0.5975 0.5973
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Schistosoma mansoni serine/threonine protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi Variant SH3 domain containing protein 0.1227 0.5975 0.5973
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0822 0.3996 0.3993
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0035 0.0076
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Entamoeba histolytica SH2-protein kinase domain containing protein 0.1227 0.5975 0.5973
Onchocerca volvulus 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.1227 0.5975 0.5973
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.2049 1 1
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/EPH protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0822 0.3996 0.3993
Brugia malayi cytokine inducible SH2-containing protein 5 0.1227 0.5975 0.5973
Brugia malayi Protein kinase domain containing protein 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.023 0.1095 0.1091
Brugia malayi Guanylyl cyclase protein 23 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Loa Loa (eye worm) TK/FAK protein kinase 0.0822 0.3996 0.3993
Schistosoma mansoni growth factor receptor-bound protein 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Schistosoma mansoni hypothetical protein 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica ankyrin repeat protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Echinococcus granulosus SHC transforming protein 3 0.1227 0.5975 0.5973
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0822 0.3996 0.3993
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Loa Loa (eye worm) TK/CSK protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0051
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica hypothetical protein, conserved 0.0822 0.3996 0.3993
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.0189 0.0184
Loa Loa (eye worm) TK/FER protein kinase 0.2049 1 1
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0084 0.008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0063 0.0147
Brugia malayi integrin-linked kinase 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Src42A 0.2049 1 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.2049 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Schistosoma mansoni DNA polymerase eta 0.0019 0.0063 0.0059
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine protein kinase 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Onchocerca volvulus 0.0822 0.3996 0.3993
Mycobacterium ulcerans hypothetical protein 0.0023 0.0084 1
Echinococcus multilocularis growth factor receptor bound protein 2 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase Src64B 0.2049 1 1
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0189 0.0184
Trypanosoma brucei protein kinase, putative 0.0822 0.3996 1
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.2049 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0822 0.3996 0.3993
Trichomonas vaginalis AGC family protein kinase 0.0822 0.3996 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.1227 0.5975 0.5973
Schistosoma mansoni tyrosine kinase 0.2049 1 1
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0822 0.3996 1
Brugia malayi STAT protein, DNA binding domain containing protein 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica tyrosine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0063 0.0059
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus granulosus c src tyrosine kinase 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0056 0.0051
Echinococcus multilocularis tyrosine protein kinase shark 0.2049 1 1
Echinococcus multilocularis 0.1227 0.5975 0.5973
Entamoeba histolytica SH2 domain containing protein 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0822 0.3996 0.3993
Brugia malayi Furin-like cysteine rich region family protein 0.0822 0.3996 0.3993
Toxoplasma gondii STE kinase 0.0822 0.3996 1
Leishmania major DNA polymerase eta, putative 0.0019 0.0063 0.0147
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Onchocerca volvulus 0.0822 0.3996 0.3993
Schistosoma mansoni tensin 0.1227 0.5975 0.5973
Schistosoma mansoni signal transduction protein lnk-related 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0822 0.3996 0.3993
Onchocerca volvulus 0.2049 1 1
Plasmodium falciparum protein kinase, putative 0.0822 0.3996 1
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0822 0.3996 0.3993
Brugia malayi Tyrosine-protein kinase abl-1 0.2049 1 1
Trichomonas vaginalis TK family protein kinase 0.0822 0.3996 1
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0063 0.0147
Loa Loa (eye worm) sex muscle abnormal protein 5 0.1227 0.5975 0.5973
Entamoeba histolytica serine/threonine kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0822 0.3996 0.3993
Giardia lamblia Kinase 0.0822 0.3996 1
Echinococcus granulosus tyrosine protein kinase Srms 0.2049 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0051 0.6071
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Schistosoma mansoni tensin 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase Blk 0.2049 1 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0005 0.0546
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0063 0.7511
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Echinococcus granulosus kinase suppressor of Ras 1 0.0822 0.3996 0.3993
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Brugia malayi Tensin 0.1227 0.5975 0.5973
Echinococcus granulosus tyrosine protein kinase csk 0.0822 0.3996 0.3993
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Entamoeba histolytica protein kinase, putative 0.0822 0.3996 0.3993
Echinococcus multilocularis kinase suppressor of Ras 1 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Echinococcus multilocularis tyrosine protein kinase Blk 0.2049 1 1
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Echinococcus multilocularis protein KINase family member (kin 25) 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Schistosoma mansoni protein kinase 0.0822 0.3996 0.3993
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Brugia malayi ephrin receptor 1 precursor 0.0822 0.3996 0.3993
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Echinococcus granulosus tyrosine protein kinase ABL1 0.2049 1 1
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine kinase 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Schistosoma mansoni tensin 0.1227 0.5975 0.5973
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Entamoeba histolytica hypothetical protein 0.0822 0.3996 0.3993
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.2049 1 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase HCK 0.0822 0.3996 0.3993
Echinococcus multilocularis transfer RNA-Thr 0.0822 0.3996 0.3993
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0056 0.0128
Schistosoma mansoni survival motor neuron protein 0.0047 0.0201 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0822 0.3996 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.0189 0.0184
Loa Loa (eye worm) RGC/RGC protein kinase 0.0822 0.3996 0.3993
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0084 0.008
Schistosoma mansoni tyrosine kinase 0.0822 0.3996 0.3993
Leishmania major protein kinase, putative 0.0822 0.3996 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0063 0.0147
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0063 0.0147
Entamoeba histolytica protein kinase domain containing protein 0.0822 0.3996 0.3993
Echinococcus granulosus tyrosine protein kinase shark 0.2049 1 1
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0005 0.0546
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0822 0.3996 0.3993
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.1227 0.5975 0.5973
Brugia malayi Immunoglobulin I-set domain containing protein 0.0822 0.3996 0.3993
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0056 0.0128
Echinococcus granulosus tyrosine kinase 0.2049 1 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2049 1 1
Echinococcus granulosus tensin C1 domain containing phosphatase 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Giardia lamblia Kinase, NEK 0.0822 0.3996 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.2049 1 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Brugia malayi Protein kinase domain containing protein 0.0822 0.3996 0.3993
Brugia malayi SH2 domain containing protein 0.2049 1 1
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0822 0.3996 0.3993
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0822 0.3996 0.3993
Echinococcus granulosus NCK adaptor protein 0.1227 0.5975 0.5973
Plasmodium vivax tyrosine kinase-like protein, putative 0.0822 0.3996 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.2049 1 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.2049 1 1
Loa Loa (eye worm) hypothetical protein 0.1227 0.5975 0.5973
Echinococcus multilocularis SH2 domain containing protein 7 0.1227 0.5975 0.5973
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trichomonas vaginalis TKL family protein kinase 0.0822 0.3996 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0822 0.3996 1
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.1227 0.5975 0.5973

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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