Detailed information for compound 1782251

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 480.478 | Formula: C27H23F3N2O3
  • H donors: 1 H acceptors: 3 LogP: 5.24 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN1c2ccc(cc2N(C(=O)C2(C1=O)CC(c1c2ccc(c1)O)C)c1ccccc1)C(F)(F)F
  • InChi: 1S/C27H23F3N2O3/c1-3-31-22-12-9-17(27(28,29)30)13-23(22)32(18-7-5-4-6-8-18)25(35)26(24(31)34)15-16(2)20-14-19(33)10-11-21(20)26/h4-14,16,33H,3,15H2,1-2H3
  • InChiKey: JSGUOWPTTFDGBZ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0021 0.0332 0.0332
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0041 0.1042 0.1123
Brugia malayi RE15519p 0.0041 0.1042 0.1123
Echinococcus granulosus bloom syndrome protein 0.0016 0.015 0.015
Echinococcus granulosus biogenic amine 5HT receptor 0.0041 0.1042 0.1042
Brugia malayi Doublecortin family protein 0.002 0.0305 0.0329
Echinococcus multilocularis Squalene phytoene synthase 0.0057 0.161 0.161
Trichomonas vaginalis DNA helicase recq1, putative 0.0016 0.015 0.008
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0108 0.3391 0.3391
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0014 0.0083 0.0083
Brugia malayi AKH receptor 0.0041 0.1042 0.1123
Brugia malayi Bloom's syndrome protein homolog 0.0016 0.015 0.0162
Echinococcus multilocularis sex peptide receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0049 0.1329 0.1432
Trichomonas vaginalis set domain proteins, putative 0.0172 0.5657 0.6362
Echinococcus multilocularis neuropeptide receptor A26 0.0041 0.1042 0.1042
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0036 0.0871 0.0871
Echinococcus multilocularis neuropeptides capa receptor 0.0041 0.1042 0.1042
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.008 0.0648
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.5993 0.6745
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0332 0.0332
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0041 0.1042 0.1123
Onchocerca volvulus 0.0041 0.1042 0.1376
Entamoeba histolytica myo-inositol monophosphatase, putative 0.003 0.067 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.1232 1
Brugia malayi putative neuropeptide receptor NPR1 0.0041 0.1042 0.1123
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0052 0.1436 0.1548
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus neuropeptide Y receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis lamin 0.0049 0.1329 0.1329
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0056 0.1576 0.1576
Onchocerca volvulus 0.0041 0.1042 0.1376
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Onchocerca volvulus 0.0041 0.1042 0.1376
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.005 0.136 0.136
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0108 0.3391 0.3391
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.067 0.1107
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0305 0.2474
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni aryl hydrocarbon receptor 0.0039 0.0978 0.0978
Onchocerca volvulus Huntingtin homolog 0.0101 0.3152 0.531
Brugia malayi bHLH-PAS transcription factor 0.0029 0.0619 0.0668
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0014 0.0083 0.0083
Schistosoma mansoni tar DNA-binding protein 0.0052 0.1436 0.1436
Onchocerca volvulus 0.0041 0.1042 0.1376
Schistosoma mansoni biogenic amine receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0305 0.0305
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0871 0.0871
Echinococcus multilocularis tar DNA binding protein 0.0052 0.1436 0.1436
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0056 0.1576 0.1576
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0016 0.015 0.0162
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0022 0.0362 0.0362
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0305 0.0305
Echinococcus granulosus hypothetical protein 0.0041 0.1042 0.1042
Schistosoma mansoni growth hormone secretagogue receptor 0.0041 0.1042 0.1042
Echinococcus granulosus 7tm_1 domain containing protein 0.0041 0.1042 0.1042
Trichomonas vaginalis inositol monophosphatase, putative 0.003 0.067 0.0673
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.1103 0.1103
Echinococcus granulosus g protein coupled receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) melatonin receptor type 1A 0.0041 0.1042 0.1123
Echinococcus granulosus glutamate receptor 2 0.0014 0.0083 0.0083
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0041 0.1042 0.1376
Echinococcus granulosus g protein coupled receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0043 0.1103 0.1103
Onchocerca volvulus Huntingtin homolog 0.0101 0.3152 0.531
Echinococcus multilocularis serotonin receptor 0.0226 0.7555 0.7555
Schistosoma mansoni DNA helicase recq1 0.0016 0.015 0.015
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.067 0.1107
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0027 0.0558 0.5
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0263 0.8846 0.9534
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0014 0.0083 0.0083
Brugia malayi Melatonin receptor type 1A 0.0041 0.1042 0.1123
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Schistosoma mansoni lamin 0.0049 0.1329 0.1329
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0016 0.015 0.1218
Onchocerca volvulus 0.0041 0.1042 0.1376
Toxoplasma gondii aldehyde dehydrogenase 0.005 0.136 1
Echinococcus multilocularis fmrfamide receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis nmda type glutamate receptor 0.0101 0.3159 0.3159
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0027 0.0558 0.3124
Loa Loa (eye worm) hypoxia-induced factor 1 0.0121 0.3867 0.4167
Brugia malayi TAR-binding protein 0.0052 0.1436 0.1548
Brugia malayi hypoxia-induced factor 1 0.0121 0.3867 0.4167
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.008 0.0648
Onchocerca volvulus 0.0041 0.1042 0.1376
Schistosoma mansoni tar DNA-binding protein 0.0052 0.1436 0.1436
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.005 0.136 0.8366
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.8846 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni amine GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni amine GPCR 0.0041 0.1042 0.1042
Echinococcus granulosus Squalene phytoene synthase 0.0057 0.161 0.161
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni lipoxygenase 0.0056 0.1576 0.1576
Loa Loa (eye worm) jmjC domain-containing protein 0.0043 0.1103 0.1189
Giardia lamblia Sgs1 DNA helicase, putative 0.0016 0.015 0.1298
Loa Loa (eye worm) hypothetical protein 0.0022 0.0362 0.0391
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0036 0.0871 0.0939
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.003 0.067 0.1107
Echinococcus multilocularis g-protein coupled receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0226 0.7555 0.8142
Onchocerca volvulus Neuropeptide F receptor homolog 0.0041 0.1042 0.1376
Schistosoma mansoni biogenic amine receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0041 0.1042 0.1042
Mycobacterium ulcerans phytoene synthase, CrtB 0.0057 0.161 0.2287
Loa Loa (eye worm) TAR-binding protein 0.0052 0.1436 0.1548
Mycobacterium ulcerans aldehyde dehydrogenase 0.005 0.136 0.1913
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0041 0.1042 0.1123
Onchocerca volvulus 0.0041 0.1042 0.1376
Onchocerca volvulus 0.0049 0.1329 0.191
Loa Loa (eye worm) hypothetical protein 0.0023 0.0402 0.0433
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0023 0.0419 0.0506
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0332 0.0332
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0041 0.1042 0.1042
Echinococcus granulosus histone acetyltransferase KAT2B 0.0105 0.3285 0.3285
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.008 0.0132
Mycobacterium ulcerans glutaminase 0.0204 0.6771 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) TYRA-2 protein 0.0041 0.1042 0.1123
Toxoplasma gondii exonuclease III APE 0.0014 0.008 0.0587
Schistosoma mansoni ap endonuclease 0.0014 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0101 0.3152 0.3397
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi jmjC domain containing protein 0.0043 0.1103 0.1189
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.005 0.136 0.136
Schistosoma mansoni biogenic amine receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.008 0.0086
Brugia malayi Dopamine receptor protein 1 0.0041 0.1042 0.1123
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0041 0.1042 0.1123
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0263 0.8846 0.9534
Loa Loa (eye worm) RecQ helicase 0.0016 0.015 0.0162
Loa Loa (eye worm) hypothetical protein 0.0101 0.3152 0.3397
Echinococcus multilocularis G-protein coupled receptor, putative 0.0041 0.1042 0.1042
Brugia malayi acetyltransferase, GNAT family protein 0.0108 0.3391 0.3655
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Leishmania major hypothetical protein, conserved 0.0046 0.1232 0.2037
Loa Loa (eye worm) hypothetical protein 0.002 0.0305 0.0329
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0021 0.0334 0.0334
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0016 0.015 0.015
Echinococcus multilocularis g protein coupled receptor 0.0041 0.1042 0.1042
Echinococcus granulosus neuropeptides capa receptor 0.0041 0.1042 0.1042
Echinococcus granulosus fmrfamide receptor 0.0041 0.1042 0.1042
Leishmania major hypothetical protein, conserved 0.0057 0.161 0.2661
Trichomonas vaginalis glucosylceramidase, putative 0.0182 0.5993 0.6745
Mycobacterium ulcerans putative regulatory protein 0.0029 0.0619 0.0806
Brugia malayi RNA binding protein 0.0052 0.1436 0.1548
Echinococcus granulosus histone lysine methyltransferase setb 0.0022 0.0362 0.0362
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0032 0.0714 0.0724
Brugia malayi hypothetical protein 0.0101 0.3152 0.3397
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0041 0.1042 0.1042
Trypanosoma brucei squalene synthase, putative 0.0183 0.6051 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.1232 0.2037
Echinococcus multilocularis RUN 0.002 0.0305 0.0305
Onchocerca volvulus 0.0041 0.1042 0.1376
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus histone acetyltransferase KAT2B 0.0032 0.0714 0.0714
Schistosoma mansoni hypothetical protein 0.0039 0.0956 0.0956
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0043 0.1103 0.1103
Onchocerca volvulus 0.0041 0.1042 0.1376
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0036 0.0871 0.0871
Echinococcus multilocularis orexin receptor type 2 0.0041 0.1042 0.1042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0022 0.0362 0.0362
Echinococcus granulosus nmda type glutamate receptor 0.0101 0.3159 0.3159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.015 0.0248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Brugia malayi RNA recognition motif domain containing protein 0.0052 0.1436 0.1548
Loa Loa (eye worm) RNA binding protein 0.0052 0.1436 0.1548
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0041 0.1042 0.1042
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0026 0.0526 0.0567
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.002 0.0305 0.0329
Schistosoma mansoni adenoreceptor 0.0041 0.1042 0.1042
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.5666 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0014 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Plasmodium falciparum histone acetyltransferase GCN5 0.0029 0.0621 0.504
Onchocerca volvulus 0.0041 0.1042 0.1376
Toxoplasma gondii LsmAD domain-containing protein 0.0046 0.1232 0.9063
Echinococcus multilocularis serotonin receptor 0.0226 0.7555 0.7555
Onchocerca volvulus 0.0041 0.1042 0.1376
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0023 0.0419 1
Loa Loa (eye worm) glutaminase 2 0.0204 0.6771 0.7297
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0275 0.9279 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0041 0.1042 0.1042
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.003 0.067 0.4927
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0041 0.1042 0.1042
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.1103 0.1103
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0022 0.0362 0.2665
Schistosoma mansoni neuropeptide receptor 0.0041 0.1042 0.1042
Trichomonas vaginalis glutaminase, putative 0.0204 0.6771 0.7633
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0048 0.1297 0.1398
Onchocerca volvulus 0.0172 0.5657 0.9983
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) acetyltransferase 0.0108 0.3391 0.3655
Brugia malayi glutaminase DH11.1 0.0204 0.6771 0.7297
Trichomonas vaginalis bromodomain-containing protein, putative 0.0032 0.0714 0.0724
Brugia malayi GnHR receptor homolog 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0024 0.0434 0.0468
Echinococcus granulosus G protein coupled receptor 139 0.0041 0.1042 0.1042
Echinococcus multilocularis allatostatin A receptor 0.0041 0.1042 0.1042
Brugia malayi G-protein coupled receptor 0.0041 0.1042 0.1123
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0032 0.0714 0.5251
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0871 0.0871
Schistosoma mansoni neuropeptide receptor 0.0041 0.1042 0.1042
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Loa Loa (eye worm) G-protein coupled receptor 0.0041 0.1042 0.1123
Echinococcus granulosus tachykinin peptides receptor 99D 0.0041 0.1042 0.1042
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.067 0.0673
Onchocerca volvulus 0.0041 0.1042 0.1376
Schistosoma mansoni tar DNA-binding protein 0.0052 0.1436 0.1436
Loa Loa (eye worm) hypothetical protein 0.0046 0.1232 0.1328
Echinococcus granulosus sex peptide receptor 0.0041 0.1042 0.1042
Schistosoma mansoni hypothetical protein 0.002 0.0305 0.0305
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0041 0.1042 0.1042
Echinococcus multilocularis G protein coupled receptor 139 0.0041 0.1042 0.1042
Brugia malayi larval opioid receptor 0.0041 0.1042 0.1123
Brugia malayi Inositol-1 0.003 0.067 0.0722
Echinococcus granulosus single minded 2 0.0029 0.0619 0.0619
Echinococcus multilocularis bloom syndrome protein 0.0016 0.015 0.015
Echinococcus granulosus lamin dm0 0.0049 0.1329 0.1329
Schistosoma mansoni tar DNA-binding protein 0.0052 0.1436 0.1436
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.8846 1
Brugia malayi G-protein coupled receptor 0.0041 0.1042 0.1123
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0151 0.4922 0.5304
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0041 0.1042 0.1042
Schistosoma mansoni hypothetical protein 0.0041 0.1042 0.1042
Brugia malayi intermediate filament protein 0.0049 0.1329 0.1432
Loa Loa (eye worm) inositol-1 0.003 0.067 0.0722
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.003 0.067 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.161 0.1735
Echinococcus multilocularis neuropeptide FF receptor 2 0.0041 0.1042 0.1042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni neuropeptide F-like receptor 0.0041 0.1042 0.1042
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0305 0.0305
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0041 0.1042 0.1042
Echinococcus multilocularis glutamate receptor 2 0.0014 0.0083 0.0083
Trichomonas vaginalis DNA helicase recq, putative 0.0016 0.015 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.008 0.0132
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0041 0.1042 0.1042
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0014 0.0083 0.0083
Schistosoma mansoni hypothetical protein 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi neuropeptide F receptor 0.0041 0.1042 0.1123
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.008 0.0132
Echinococcus granulosus tm gpcr rhodopsin 0.0041 0.1042 0.1042
Brugia malayi follicle stimulating hormone receptor 0.0275 0.9279 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.1329 0.1432
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0032 0.0714 0.5794
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni aldehyde dehydrogenase 0.005 0.136 0.136
Brugia malayi Intermediate filament tail domain containing protein 0.0049 0.1329 0.1432
Loa Loa (eye worm) hypothetical protein 0.0023 0.0402 0.0433
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.015 0.1104
Echinococcus granulosus biogenic amine 5HT receptor 0.0226 0.7555 0.7555
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Loa Loa (eye worm) hypothetical protein 0.002 0.0305 0.0329
Echinococcus granulosus lysine specific demethylase 5A 0.0043 0.1103 0.1103
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.1232 1
Echinococcus multilocularis inositol monophosphatase 1 0.003 0.067 0.067
Onchocerca volvulus 0.0041 0.1042 0.1376
Brugia malayi Dopamine receptor 0.0041 0.1042 0.1123
Echinococcus multilocularis g protein coupled receptor 0.0041 0.1042 0.1042
Schistosoma mansoni neuropeptide receptor 0.0041 0.1042 0.1042
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0057 0.161 0.2434
Entamoeba histolytica recQ family helicase, putative 0.0016 0.015 0.1191
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0041 0.1042 0.1123
Schistosoma mansoni amine GPCR 0.0041 0.1042 0.1042
Onchocerca volvulus 0.0041 0.1042 0.1376
Echinococcus granulosus allatostatin A receptor 0.0041 0.1042 0.1042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Plasmodium vivax ataxin-2 like protein, putative 0.0046 0.1232 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0036 0.0871 0.0939
Schistosoma mansoni rab6-interacting 0.002 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0131 0.4225 0.4554
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0057 0.161 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.005 0.136 0.1913
Echinococcus multilocularis musashi 0.0049 0.1329 0.1329
Echinococcus granulosus glutamate receptor NMDA 0.0096 0.2995 0.2995
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0041 0.1042 0.1042
Schistosoma mansoni jumonji domain containing protein 0.0043 0.1103 0.1103
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0016 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0226 0.7555 0.8142
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus serotonin receptor 0.0041 0.1042 0.1042
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0305 0.0305
Trypanosoma cruzi squalene synthase, putative 0.0183 0.6051 1
Echinococcus granulosus neuropeptide receptor A26 0.0041 0.1042 0.1042
Entamoeba histolytica acetyltransferase, GNAT family 0.0029 0.0621 0.9172
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni hypothetical protein 0.0295 1 1
Brugia malayi putative neuropeptide receptor 0.0041 0.1042 0.1123
Brugia malayi Serotonin receptor 0.0041 0.1042 0.1123
Schistosoma mansoni DNA helicase recq5 0.0016 0.015 0.015
Schistosoma mansoni hypothetical protein 0.0295 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi G protein-coupled receptor F59B2.13 0.0041 0.1042 0.1123
Echinococcus granulosus tm gpcr rhodopsin 0.0041 0.1042 0.1042
Echinococcus multilocularis somatostatin receptor 0.0041 0.1042 0.1042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0036 0.0871 0.0871
Loa Loa (eye worm) doublecortin family protein 0.002 0.0305 0.0329
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Echinococcus granulosus neuropeptides capa receptor 0.0041 0.1042 0.1042
Schistosoma mansoni intermediate filament proteins 0.0049 0.1329 0.1329
Schistosoma mansoni lipoxygenase 0.002 0.0305 0.0305
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0016 0.015 0.015
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni biogenic amine (5HT) receptor 0.0041 0.1042 0.1042
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.008 0.008
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0305 0.2474
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis fmrfamide receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0022 0.0362 0.0362
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni glutaminase 0.0204 0.6771 0.6771
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus intermediate filament protein 0.0049 0.1329 0.1329
Echinococcus granulosus g protein coupled receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi cytoplasmic intermediate filament protein 0.0026 0.0526 0.0567
Echinococcus multilocularis neuropeptide receptor 0.0041 0.1042 0.1042
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.008 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0041 0.1042 0.1042
Echinococcus granulosus 7TM GPCR rhodopsin 0.0041 0.1042 0.1042
Schistosoma mansoni amine GPCR 0.0041 0.1042 0.1042
Echinococcus granulosus lamin 0.0049 0.1329 0.1329
Schistosoma mansoni hypothetical protein 0.0057 0.161 0.161
Loa Loa (eye worm) neuropeptide F receptor 0.0041 0.1042 0.1123
Echinococcus granulosus neuropeptide receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) neuropeptide F receptor 0.0041 0.1042 0.1123
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.015 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0362 0.0362
Brugia malayi Dopamine receptor protein 2 0.0041 0.1042 0.1123
Schistosoma mansoni glutamate receptor NMDA 0.011 0.3479 0.3479
Echinococcus multilocularis neuropeptide receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0036 0.0871 0.0871
Echinococcus granulosus g-protein coupled receptor 0.0041 0.1042 0.1042
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0024 0.0434 0.0434
Schistosoma mansoni inositol monophosphatase 0.003 0.067 0.067
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0041 0.1042 0.1042
Leishmania major squalene synthase, putative 0.0183 0.6051 1
Schistosoma mansoni tar DNA-binding protein 0.0052 0.1436 0.1436
Brugia malayi PAS domain containing protein 0.0039 0.0978 0.1054
Schistosoma mansoni neuropeptide receptor 0.0041 0.1042 0.1042
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.8846 1
Echinococcus granulosus dro:myosuppressin receptor 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0041 0.1042 0.1123
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis glutamate receptor NMDA 0.0096 0.2995 0.2995
Trypanosoma brucei PAB1-binding protein , putative 0.0046 0.1232 0.2037
Schistosoma mansoni myosin xvIII 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.8846 1
Brugia malayi jmjC domain containing protein 0.0043 0.1103 0.1189
Schistosoma mansoni neuropeptide F-like receptor 0.0041 0.1042 0.1042
Echinococcus granulosus peptide allatostatin:somatostatin 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.8846 1
Schistosoma mansoni inositol monophosphatase 0.003 0.067 0.067
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0014 0.0083 0.0083
Echinococcus multilocularis neuropeptides capa receptor 0.0041 0.1042 0.1042
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Onchocerca volvulus 0.0041 0.1042 0.1376
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi sulfakinin receptor protein 0.0041 0.1042 0.1123
Schistosoma mansoni biogenic amine (5HT) receptor 0.0226 0.7555 0.7555
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis neuropeptide s receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis g protein coupled receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.008 0.0132
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0305 0.0305
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0041 0.1042 0.1042
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0041 0.1042 0.1042
Echinococcus granulosus somatostatin receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0016 0.015 0.0162
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0305 0.0305
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0041 0.1042 0.1042
Schistosoma mansoni alpha-1 adrenergic receptor 0.0041 0.1042 0.1042
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0032 0.0714 0.5251
Echinococcus granulosus neuropeptide receptor 0.0041 0.1042 0.1042
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni aldehyde dehydrogenase 0.005 0.136 0.136
Brugia malayi Pre-SET motif family protein 0.0022 0.0362 0.0391
Echinococcus granulosus tm gpcr rhodopsin 0.0041 0.1042 0.1042
Chlamydia trachomatis glutamine binding protein 0.0023 0.0419 0.5
Schistosoma mansoni hypothetical protein 0.0041 0.1042 0.1042
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0016 0.015 0.1218
Onchocerca volvulus 0.0029 0.0619 0.0587
Schistosoma mansoni polycystin 1-related 0.002 0.0305 0.0305
Schistosoma mansoni rab6-interacting 0.002 0.0305 0.0305
Echinococcus multilocularis neuropeptide Y receptor 0.0041 0.1042 0.1042
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0014 0.0083 0.0083
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0016 0.015 0.015
Echinococcus granulosus nmda type glutamate receptor 0.0129 0.4135 0.4135
Trichomonas vaginalis DNA helicase recq, putative 0.0016 0.015 0.008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.005 0.136 0.2247
Schistosoma mansoni neuropeptide f receptor 76f 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.0046 0.1232 0.1328
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.015 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0362 0.0362
Schistosoma mansoni hypothetical protein 0.0041 0.1042 0.1042
Onchocerca volvulus 0.0049 0.1329 0.191
Echinococcus granulosus RUN 0.002 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0023 0.0419 0.2215
Brugia malayi ORL1-like opioid receptor 0.0041 0.1042 0.1123
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni histamine h1 receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus granulosus inositol monophosphatase 1 0.003 0.067 0.067
Echinococcus multilocularis geminin 0.0295 1 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0024 0.0434 0.0434
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0036 0.0871 0.0871
Loa Loa (eye worm) intermediate filament protein 0.0049 0.1329 0.1432
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.0131 0.4225 0.4554
Mycobacterium ulcerans aldehyde dehydrogenase 0.005 0.136 0.1913
Trypanosoma cruzi squalene synthase, putative 0.0183 0.6051 1
Echinococcus multilocularis lamin dm0 0.0049 0.1329 0.1329
Brugia malayi Pre-SET motif family protein 0.0151 0.4922 0.5304
Echinococcus multilocularis neuropeptide Y receptor 0.0041 0.1042 0.1042
Schistosoma mansoni amine GPCR 0.0041 0.1042 0.1042
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.1232 0.2037
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0023 0.0419 1
Trichomonas vaginalis glucosylceramidase, putative 0.0263 0.8846 1
Echinococcus granulosus tar DNA binding protein 0.0052 0.1436 0.1436
Onchocerca volvulus 0.0041 0.1042 0.1376
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0041 0.1042 0.1123
Loa Loa (eye worm) glutaminase 0.0204 0.6771 0.7297
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Brugia malayi neuropeptide F receptor 0.0041 0.1042 0.1123
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.008 0.008
Echinococcus granulosus neuropeptide Y receptor 0.0041 0.1042 0.1042
Schistosoma mansoni single-minded 0.0039 0.0978 0.0978
Trypanosoma cruzi phytoene synthase, putative 0.0057 0.161 0.2661
Brugia malayi Tachykinin-like peptides receptor 99D 0.0041 0.1042 0.1123
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.067 0.1107
Echinococcus granulosus orexin receptor type 2 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Echinococcus granulosus alpha 1A adrenergic receptor 0.0041 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Brugia malayi G protein-coupled receptor 0.0041 0.1042 0.1123
Echinococcus multilocularis transfer RNA-Lys 0.0029 0.0619 0.0619
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0014 0.0083 0.0083
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0041 0.1042 0.1042
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.015 0.1104
Echinococcus granulosus neuropeptide s receptor 0.0041 0.1042 0.1042
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.067 0.0673
Schistosoma mansoni opsin-like receptor 0.0041 0.1042 0.1042
Brugia malayi hypothetical protein 0.002 0.0305 0.0329
Onchocerca volvulus 0.0022 0.0362 0.0107
Loa Loa (eye worm) G-protein coupled receptor 0.0041 0.1042 0.1123
Schistosoma mansoni jumonji/arid domain-containing protein 0.0043 0.1103 0.1103
Plasmodium vivax SET domain protein, putative 0.0022 0.0362 0.294
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123
Schistosoma mansoni lamin 0.0049 0.1329 0.1329
Schistosoma mansoni loxhd1 0.002 0.0305 0.0305
Schistosoma mansoni opsin-like receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis nmda type glutamate receptor 0.0129 0.4135 0.4135
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0739 0.0739
Brugia malayi Serotonin receptor 0.0041 0.1042 0.1123
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0041 0.1042 0.1042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0041 0.1042 0.1042
Schistosoma mansoni opsin-like receptor 0.0041 0.1042 0.1042
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0041 0.1042 0.1042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0022 0.0362 0.0362
Echinococcus granulosus neuropeptide FF receptor 2 0.0041 0.1042 0.1042
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0041 0.1042 0.1042
Onchocerca volvulus 0.0041 0.1042 0.1376
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.003 0.067 0.0882
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.5666 0.6373
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0023 0.0419 0.5
Loa Loa (eye worm) hypothetical protein 0.0016 0.015 0.0162
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0016 0.015 0.0162
Brugia malayi hypothetical protein 0.0041 0.1042 0.1123
Brugia malayi hypothetical protein 0.003 0.0653 0.0704
Schistosoma mansoni ap endonuclease 0.0014 0.008 0.008
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0041 0.1042 0.1123
Echinococcus granulosus rhodopsin orphan GPCR 0.0041 0.1042 0.1042
Giardia lamblia Histone acetyltransferase GCN5 0.0029 0.0621 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.1042 0.1123

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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