TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 539.623 | Formula: C28H37N5O6
H donors: 3 H acceptors: 4 LogP: -0.1 Rotable bonds: 10
Rule of 5 violations (Lipinski): 2
SMILES: CC(=O)O.CCOC(=O)C1CCN(CC1)c1ccc(cc1)N1C[C@H](OC1=O)CNCc1ccc(cc1)C(=N)N
InChi: 1S/C26H33N5O4.C2H4O2/c1-2-34-25(32)20-11-13-30(14-12-20)21-7-9-22(10-8-21)31-17-23(35-26(31)33)16-29-15-18-3-5-19(6-4-18)24(27)28;1-2(3)4/h3-10,20,23,29H,2,11-17H2,1H3,(H3,27,28);1H3,(H,3,4)/t23-;/m1./s1
InChiKey: SOOTZKGTHQLOBA-GNAFDRTKSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	protease, serine, 3	Starlite/ChEMBL	References
Homo sapiens	protease, serine, 1 (trypsin 1)		References
Homo sapiens	protease, serine, 2 (trypsin 2)		References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	Get druggable targets OG5_126639	All targets in OG5_126639
Brugia malayi	Trypsin family protein	Get druggable targets OG5_126639	All targets in OG5_126639
Onchocerca volvulus		Get druggable targets OG5_126639	All targets in OG5_126639
Onchocerca volvulus		Get druggable targets OG5_126639	All targets in OG5_126639
Schistosoma japonicum	ko:K09639 transmembrane protease, serine 8, putative	Get druggable targets OG5_126639	All targets in OG5_126639
Schistosoma japonicum	ko:K09639 transmembrane protease, serine 8, putative	Get druggable targets OG5_126639	All targets in OG5_126639
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	Get druggable targets OG5_126639	All targets in OG5_126639
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126639	All targets in OG5_126639
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126639	All targets in OG5_126639

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Schistosoma mansoni	cercarial elastase (S01 family)	protease, serine, 2 (trypsin 2)	247 aa	240 aa	25.8 %
Brugia malayi	Trypsin family protein	protease, serine, 1 (trypsin 1)	247 aa	287 aa	21.6 %
Schistosoma mansoni	cercarial elastase (S01 family)	protease, serine, 3	261 aa	234 aa	25.2 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	unc 13 (munc13)	0.0087	0.0091	0.0091
Toxoplasma gondii	peptidase family M13 protein	0.0573	0.2097	1
Schistosoma mansoni	serine/threonine protein kinase	0.0087	0.0091	0.0091
Echinococcus multilocularis	serotonin receptor	0.0132	0.028	0.028
Brugia malayi	Protein kinase domain containing protein	0.0087	0.0091	0.0094
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0087	0.0091	0.0091
Brugia malayi	Protein kinase c protein 2	0.0087	0.0091	0.0094
Loa Loa (eye worm)	matrixin family protein	0.0122	0.0237	0.0239
Loa Loa (eye worm)	matrixin family protein	0.0133	0.0282	0.0284
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.014	0.031	0.031
Schistosoma mansoni	protein kinase C	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0423	0.148	0.1492
Plasmodium falciparum	cysteine repeat modular protein 4	0.0081	0.0066	0.5
Entamoeba histolytica	diacylglycerol kinase, putative	0.0087	0.0091	1
Onchocerca volvulus		0.0087	0.0091	0.0117
Schistosoma mansoni	hypothetical protein	0.0087	0.0091	0.0091
Schistosoma mansoni	hypothetical protein	0.0149	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0132	0.028	0.0283
Schistosoma mansoni	hypothetical protein	0.0081	0.0066	0.0066
Schistosoma mansoni	serine/threonine protein kinase	0.0087	0.0091	0.0091
Schistosoma mansoni	hypothetical protein	0.0149	0.0351	0.0351
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0341	0.1142	0.1142
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1521	0.1534
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0087	0.0091	0.0091
Brugia malayi	protein kinase C3,putative	0.0087	0.0091	0.0094
Brugia malayi	Hypothetical zinc metalloproteinase T16A9.4	0.0573	0.2097	0.2174
Schistosoma mansoni	protein kinase C mu	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0284	0.0905	0.0912
Echinococcus multilocularis	Rac GTPase activating protein 1	0.0087	0.0091	0.0091
Echinococcus multilocularis	N chimaerin	0.0087	0.0091	0.0091
Mycobacterium leprae	probable zinc metalloprotease	0.0573	0.2097	1
Schistosoma mansoni	serine/threonine protein kinase	0.2489	1	1
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0573	0.2097	0.2097
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Loa Loa (eye worm)	hypothetical protein	0.0423	0.148	0.1492
Brugia malayi	GCC2 and GCC3 family protein	0.0081	0.0066	0.0069
Schistosoma mansoni	diacylglycerol kinase theta	0.0087	0.0091	0.0091
Loa Loa (eye worm)	Ras association domain family 1 isoform A	0.0087	0.0091	0.0092
Onchocerca volvulus		0.0284	0.0905	0.2789
Brugia malayi	C1-like domain containing protein	0.0087	0.0091	0.0094
Loa Loa (eye worm)	hypothetical protein	0.0816	0.31	0.3126
Loa Loa (eye worm)	AGC/PKC/IOTA protein kinase	0.0087	0.0091	0.0092
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.0087	0.0091	0.0091
Brugia malayi	RhoGEF domain containing protein	0.0087	0.0091	0.0094
Schistosoma mansoni	serine/threonine protein kinase	0.0087	0.0091	0.0091
Mycobacterium ulcerans	epoxide hydrolase EphA	0.0163	0.0405	0.1891
Schistosoma mansoni	hypothetical protein	0.0149	0.0351	0.0351
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0081	0.0066	0.5
Onchocerca volvulus		0.0816	0.31	1
Echinococcus granulosus	myotubularin protein 13	0.0087	0.0091	0.0091
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0289	0.0926	0.0926
Echinococcus multilocularis	protein kinase c eta type	0.0087	0.0091	0.0091
Echinococcus granulosus	endonuclease reverse transcriptase	0.0081	0.0066	0.0066
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.1415	0.5569	0.5615
Brugia malayi	Variant SH3 domain containing protein	0.0087	0.0091	0.0094
Mycobacterium tuberculosis	Probable zinc metalloprotease Zmp1	0.0573	0.2097	0.5198
Echinococcus granulosus	C2 calcium dependent membrane targeting	0.0087	0.0091	0.0091
Plasmodium vivax	cysteine repeat modular protein 3, putative	0.0081	0.0066	0.5
Schistosoma mansoni	hypothetical protein	0.0078	0.0055	0.0055
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0423	0.148	0.1492
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0087	0.0091	0.0091
Brugia malayi	Hemopexin family protein	0.0078	0.0055	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0066	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Loa Loa (eye worm)	RasGEF domain-containing protein	0.0087	0.0091	0.0092
Echinococcus multilocularis	protein kinase c epsilon type	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1521	0.1534
Echinococcus multilocularis	serine:threonine protein kinase MRCK beta	0.0087	0.0091	0.0091
Echinococcus granulosus	leukotriene A 4 hydrolase	0.0236	0.0707	0.0707
Schistosoma mansoni	protein kinase C mu	0.0087	0.0091	0.0091
Plasmodium falciparum	cysteine repeat modular protein 3	0.0081	0.0066	0.5
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.014	0.031	0.031
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.0236	0.0707	0.0707
Loa Loa (eye worm)	hypothetical protein	0.0573	0.2097	0.2114
Brugia malayi	GCC2 and GCC3 family protein	0.0081	0.0066	0.0069
Brugia malayi	Matrixin family protein	0.0133	0.0282	0.0292
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0809	0.3069	0.3069
Loa Loa (eye worm)	raf kinase	0.2469	0.9917	1
Brugia malayi	Matrix metalloprotease, N-terminal domain containing protein	0.0067	0.001	0.001
Brugia malayi	RhoGAP domain containing protein	0.0087	0.0091	0.0094
Schistosoma mansoni	intracisternal A-particle retropepsin (A02 family)	0.1224	0.4785	0.4785
Loa Loa (eye worm)	TK/EPH protein kinase	0.1	0.386	0.3892
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0917	0.3515	0.3515
Mycobacterium tuberculosis	Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase)	0.0163	0.0405	0.0983
Brugia malayi	Peptidase family M13 containing protein	0.0573	0.2097	0.2174
Schistosoma mansoni	serine/threonine protein kinase	0.0087	0.0091	0.0091
Echinococcus multilocularis	serotonin receptor	0.0132	0.028	0.028
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.014	0.031	0.031
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0066	0.0067
Onchocerca volvulus		0.0319	0.1051	0.3268
Schistosoma mansoni	matrix metallopeptidase-9 (M10 family)	0.008	0.0065	0.0065
Schistosoma mansoni	rac gtpase activating protein	0.0087	0.0091	0.0091
Loa Loa (eye worm)	CAMK/PKD protein kinase	0.0087	0.0091	0.0092
Onchocerca volvulus		0.0081	0.0066	0.0036
Echinococcus granulosus	Diacylglycerol kinase theta	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0341	0.1142	0.1152
Schistosoma mansoni	family A2 unassigned peptidase (A02 family)	0.0223	0.0652	0.0652
Schistosoma mansoni	hypothetical protein	0.0149	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0132	0.028	0.0283
Schistosoma mansoni	hypothetical protein	0.0149	0.0351	0.0351
Entamoeba histolytica	diacylglycerol kinase, putative	0.0087	0.0091	1
Echinococcus granulosus	Rac GTPase activating protein 1	0.0087	0.0091	0.0091
Plasmodium vivax	cysteine repeat modular protein 2, putative	0.0081	0.0066	0.5
Onchocerca volvulus	Matrix metalloproteinase homolog	0.0122	0.0237	0.0595
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Schistosoma mansoni	endothelin-converting enzyme-related	0.014	0.031	0.031
Echinococcus multilocularis	endonuclease reverse transcriptase	0.0081	0.0066	0.0066
Schistosoma mansoni	atypical protein kinase C	0.0087	0.0091	0.0091
Schistosoma mansoni	unc-13 (munc13)	0.0087	0.0091	0.0091
Schistosoma mansoni	family M13 non-peptidase homologue (M13 family)	0.0289	0.0926	0.0926
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.0236	0.0707	0.0707
Schistosoma mansoni	hypothetical protein	0.0149	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1521	0.1534
Schistosoma mansoni	endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase)	0.014	0.031	0.031
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.0236	0.0707	0.0713
Brugia malayi	GCC2 and GCC3 family protein	0.0081	0.0066	0.0069
Echinococcus granulosus	ephrin type A receptor 4 A	0.0917	0.3515	0.3515
Echinococcus granulosus	N chimaerin	0.0087	0.0091	0.0091
Mycobacterium tuberculosis	Possible exported protein	0.104	0.4024	1
Schistosoma mansoni	unc-13 (munc13)	0.0087	0.0091	0.0091
Brugia malayi	diacylglycerol kinase	0.0087	0.0091	0.0094
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0066	0.0067
Loa Loa (eye worm)	peptidase family M13 containing protein	0.0423	0.148	0.1492
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0066	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1521	0.1534
Plasmodium vivax	hypothetical protein, conserved	0.0081	0.0066	0.5
Loa Loa (eye worm)	hypothetical protein	0.0067	0.001	0.001
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Schistosoma mansoni	neprilysin	0.0149	0.0351	0.0351
Echinococcus granulosus	endothelin converting enzyme 1	0.0573	0.2097	0.2097
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0087	0.0091	0.0092
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0087	0.0091	0.0092
Giardia lamblia	Hypothetical protein	0.0081	0.0066	0.5
Onchocerca volvulus		0.0081	0.0066	0.0036
Echinococcus multilocularis	raf serine:threonine protein kinase	0.2489	1	1
Mycobacterium ulcerans	zinc metalloprotease	0.0573	0.2097	1
Echinococcus multilocularis	myotubularin protein 13	0.0087	0.0091	0.0091
Plasmodium falciparum	cysteine repeat modular protein 2	0.0081	0.0066	0.5
Loa Loa (eye worm)	hypothetical protein	0.0423	0.148	0.1492
Brugia malayi	Phorbol esters/diacylglycerol binding domain	0.0087	0.0091	0.0094
Schistosoma mansoni	vav2	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1518	0.1531
Echinococcus granulosus	biogenic amine 5HT receptor	0.0132	0.028	0.028
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Echinococcus granulosus	matrix metallopeptidase 7 M10 family	0.02	0.0558	0.0558
Schistosoma mansoni	diacylglycerol kinase theta	0.0087	0.0091	0.0091
Brugia malayi	Pleckstrin Homology Domain	0.0087	0.0091	0.0094
Echinococcus granulosus	Protein kinase C brain isozyme	0.0087	0.0091	0.0091
Echinococcus multilocularis	protein kinase c iota type	0.0087	0.0091	0.0091
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0289	0.0926	0.0926
Schistosoma mansoni	Nep2 peptidase (M13 family)	0.0289	0.0926	0.0926
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.0149	0.0351	0.0351
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0341	0.1142	0.1142
Brugia malayi	Ras association domain family 1 isoform A	0.0087	0.0091	0.0094
Brugia malayi	peptidase family M13 containing protein	0.014	0.031	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0573	0.2097	0.2114
Onchocerca volvulus		0.0087	0.0091	0.0117
Echinococcus granulosus	Serine/threonine-protein kinase Genghis Khan	0.0087	0.0091	0.0091
Echinococcus multilocularis	matrix metallopeptidase 7 (M10 family)	0.02	0.0558	0.0558
Plasmodium vivax	hypothetical protein, conserved	0.0081	0.0066	0.5
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1521	0.1534
Loa Loa (eye worm)	zinc metallopeptidase 4	0.014	0.031	0.0312
Plasmodium falciparum	conserved protein, unknown function	0.0081	0.0066	0.5
Echinococcus multilocularis	endothelin converting enzyme 1	0.0573	0.2097	0.2097
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0132	0.028	0.028
Loa Loa (eye worm)	hypothetical protein	0.0341	0.1142	0.1152
Brugia malayi	protein kinase C II.	0.0087	0.0091	0.0094
Brugia malayi	GCC2 and GCC3 family protein	0.0081	0.0066	0.0069
Entamoeba histolytica	hypothetical protein	0.0087	0.0091	1
Toxoplasma gondii	diacylglycerol kinase, putative	0.0087	0.0091	0.0121
Giardia lamblia	CEGP1 protein	0.0081	0.0066	0.5
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Schistosoma mansoni	ephrin receptor	0.0836	0.3183	0.3183
Brugia malayi	diacylglycerol kinase	0.0087	0.0091	0.0094
Onchocerca volvulus		0.0341	0.1142	0.357
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Onchocerca volvulus		0.0087	0.0091	0.0117
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0091	0.0092
Echinococcus granulosus	protein kinase c eta type	0.0087	0.0091	0.0091
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0087	0.0091	0.0091
Echinococcus multilocularis	C2 calcium dependent membrane targeting	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0573	0.2097	0.2114
Brugia malayi	ephrin receptor 1 precursor	0.0421	0.1469	0.1523
Schistosoma mansoni	serine/threonine protein kinase	0.0087	0.0091	0.0091
Echinococcus multilocularis	Diacylglycerol kinase theta	0.0087	0.0091	0.0091
Plasmodium falciparum	cysteine repeat modular protein 1	0.0081	0.0066	0.5
Loa Loa (eye worm)	hypothetical protein	0.0423	0.148	0.1492
Brugia malayi	Raf kinase	0.2402	0.9643	1
Brugia malayi	hypothetical protein	0.0108	0.0181	0.0188
Brugia malayi	Trypsin family protein	0.0341	0.1142	0.1185
Brugia malayi	RhoGAP domain containing protein	0.0087	0.0091	0.0094
Echinococcus granulosus	protein kinase c iota type	0.0087	0.0091	0.0091
Echinococcus granulosus	protein kinase c epsilon type	0.0087	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0433	0.1521	0.1534
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0087	0.0091	0.0092
Schistosoma mansoni	neprilysin-2 (M13 family)	0.0289	0.0926	0.0926
Echinococcus granulosus	unc 13 munc13	0.0087	0.0091	0.0091
Onchocerca volvulus	Matrilysin homolog	0.0122	0.0237	0.0595
Schistosoma mansoni	family M13 unassigned peptidase (M13 family)	0.014	0.031	0.031

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 35 uM	Displacement of biotinylated fibrinogen from human glycoprotein 2b/3a receptor after 2 hrs by chemiluminescence assay	ChEMBL.	23644213
Ki (binding)	= 6.59 uM	Inhibition of trypsin (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis	ChEMBL.	23644213
Ki (binding)	= 25.6 uM	Inhibition of F10a (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis	ChEMBL.	23644213
Ki (binding)	> 100 uM	Inhibition of thrombin (unknown origin) using S-2238 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis	ChEMBL.	23644213

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2391195

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1782340