TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 344.431 | Formula: C17H20N4O2S
H donors: 0 H acceptors: 2 LogP: 0.97 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=C(N1CCN(CC1)C(=O)C)Cn1c(=N)scc1c1ccccc1
InChi: 1S/C17H20N4O2S/c1-13(22)19-7-9-20(10-8-19)16(23)11-21-15(12-24-17(21)18)14-5-3-2-4-6-14/h2-6,12,18H,7-11H2,1H3
InChiKey: UJTCLCSSFRMSEH-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	leukotriene A4 hydrolase	Starlite/ChEMBL	References
Homo sapiens	epidermal growth factor receptor	Starlite/ChEMBL	References
Homo sapiens	mitogen-activated protein kinase 1	Starlite/ChEMBL	References
Homo sapiens	vitamin D (1,25- dihydroxyvitamin D3) receptor	Starlite/ChEMBL	References
Homo sapiens	thymidylate synthetase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Neospora caninum	Bifunctional dihydrofolate reductase-thymidylate synthase, related	Get druggable targets OG5_127385	All targets in OG5_127385
Echinococcus multilocularis	mitogen activated protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma japonicum	Epidermal growth factor receptor precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Leishmania donovani	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Candida albicans	Serine/threonine protein kinase of MAP kinase family	Get druggable targets OG5_126781	All targets in OG5_126781
Onchocerca volvulus		Get druggable targets OG5_127385	All targets in OG5_127385
Echinococcus multilocularis	leukotriene A 4 hydrolase	Get druggable targets OG5_129538	All targets in OG5_129538
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Trichomonas vaginalis	CMGC family protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	ko:K05085 receptor tyrosine-protein kinase erbB-4, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Leishmania mexicana	mitogen activated protein kinase, putative,map kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma mansoni	bifunctional dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma japonicum	Epidermal growth factor receptor precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Loa Loa (eye worm)	thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Echinococcus granulosus	leukotriene A 4 hydrolase	Get druggable targets OG5_129538	All targets in OG5_129538
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania mexicana	mitogen-activated protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma japonicum	expressed protein	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	hypothetical protein	Get druggable targets OG5_127385	All targets in OG5_127385
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Plasmodium yoelii	thymidylate synthase, putative	Get druggable targets OG5_127385	All targets in OG5_127385
Cryptosporidium parvum	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Leishmania mexicana	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Trichomonas vaginalis	CMGC family protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Echinococcus multilocularis	mitogen activated protein kinase 3	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania donovani	mitogen activated protein kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Trypanosoma brucei gambiense	mitogen-activated protein kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Candida albicans	MAP kinase implicated in PKC1-controlled signalling pathway	Get druggable targets OG5_126781	All targets in OG5_126781
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Trypanosoma brucei	protein kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Brugia malayi	thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Candida albicans	MAP kinase-like orf	Get druggable targets OG5_126781	All targets in OG5_126781
Brugia malayi	MAP kinase sur-1	Get druggable targets OG5_126781	All targets in OG5_126781
Candida albicans	Thymidylate synthase capable of functional substitution for S. cerevisiae CDC21 (YOR074C)	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma japonicum	Tyrosine-protein kinase transforming protein erbB, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Babesia bovis	dihydrofolate reductase/thymidilate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Plasmodium knowlesi	bifunctional dihydrofolate reductase-thymidylate synthase, putative	Get druggable targets OG5_127385	All targets in OG5_127385
Brugia malayi	Furin-like cysteine rich region family protein	Get druggable targets OG5_128597	All targets in OG5_128597
Candida albicans	Serine/threonine protein kinase of MAP kinase family	Get druggable targets OG5_126781	All targets in OG5_126781
Echinococcus granulosus	epidermal growth factor receptor	Get druggable targets OG5_128597	All targets in OG5_128597
Cryptosporidium hominis	MAPK	Get druggable targets OG5_126781	All targets in OG5_126781
Echinococcus granulosus	epidermal growth factor receptor	Get druggable targets OG5_128597	All targets in OG5_128597
Leishmania braziliensis	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440,map kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma japonicum	Mitogen-activated protein kinase 3, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Plasmodium berghei	bifunctional dihydrofolate reductase-thymidylate synthase, putative	Get druggable targets OG5_127385	All targets in OG5_127385
Loa Loa (eye worm)	leukotriene A4 hydrolase	Get druggable targets OG5_129538	All targets in OG5_129538
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	Get druggable targets OG5_127385	All targets in OG5_127385
Leishmania infantum	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	Get druggable targets OG5_126781	All targets in OG5_126781
Trichomonas vaginalis	CMGC family protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma mansoni	serine/threonine protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	ko:K00560 thymidylate synthase [EC2.1.1.45], putative	Get druggable targets OG5_127385	All targets in OG5_127385
Trypanosoma congolense	tyrosine protein kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania donovani	mitogen-activated protein kinase 4	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania braziliensis	mitogen activated protein kinase, putative,map kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Cryptosporidium hominis	chain A, crystal structure of Dhfr	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Mycobacterium ulcerans	thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Leishmania braziliensis	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma japonicum	Epidermal growth factor receptor precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	IPR006212,Furin-like repeat;IPR009030,Growth factor, receptor,domain-containing	Get druggable targets OG5_128597	All targets in OG5_128597
Echinococcus multilocularis	epidermal growth factor receptor	Get druggable targets OG5_128597	All targets in OG5_128597
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Candida albicans	leukotriene A4 hydrolase/leucyl aminopeptidase	Get druggable targets OG5_129538	All targets in OG5_129538
Schistosoma japonicum	Receptor tyrosine-protein kinase erbB-2 precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Echinococcus granulosus	mitogen activated protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Cryptosporidium parvum	MAPK, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Trichomonas vaginalis	CMGC family protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Echinococcus multilocularis	thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma mansoni	tyrosine kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Candida albicans	Thymidylate synthase capable of functional substitution for S. cerevisiae CDC21 (YOR074C)	Get druggable targets OG5_127385	All targets in OG5_127385
Mycobacterium leprae	PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)	Get druggable targets OG5_127385	All targets in OG5_127385
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	Get druggable targets OG5_126781	All targets in OG5_126781
Echinococcus granulosus	mitogen activated protein kinase 3	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania major	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Mycobacterium tuberculosis	Probable thymidylate synthase ThyA (ts) (TSASE)	Get druggable targets OG5_127385	All targets in OG5_127385
Leishmania infantum	mitogen activated protein kinase, putative,map kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Candida albicans	MAP kinase-like orf	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania infantum	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma japonicum	Receptor tyrosine-protein kinase erbB-4 precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	Epidermal growth factor receptor precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Trypanosoma brucei gambiense	protein kinase, putative,tyrosine protein kinase, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma japonicum	ko:K01254 leukotriene-A4 hydrolase [EC3.3.2.6], putative	Get druggable targets OG5_129538	All targets in OG5_129538
Schistosoma japonicum	hypothetical protein	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	Epidermal growth factor receptor precursor, putative	Get druggable targets OG5_128597	All targets in OG5_128597
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma japonicum	Mitogen-activated protein kinase 3, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	Get druggable targets OG5_126781	All targets in OG5_126781
Trypanosoma brucei	mitogen activated protein kinase 4, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Schistosoma japonicum	ko:K04371 extracellular signal-regulated kinase 1/2, putative	Get druggable targets OG5_126781	All targets in OG5_126781
Candida albicans	leukotriene A4 hydrolase/leucyl aminopeptidase	Get druggable targets OG5_129538	All targets in OG5_129538
Theileria parva	dihydrofolate reductase-thymidylate synthase, putative	Get druggable targets OG5_127385	All targets in OG5_127385
Giardia lamblia	Kinase, CMGC MAPK	Get druggable targets OG5_126781	All targets in OG5_126781
Trypanosoma brucei gambiense	dihydrofolate reductase-thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	Get druggable targets OG5_129538	All targets in OG5_129538
Echinococcus granulosus	thymidylate synthase	Get druggable targets OG5_127385	All targets in OG5_127385
Echinococcus multilocularis		Get druggable targets OG5_128597	All targets in OG5_128597
Loa Loa (eye worm)	TK/EGFR protein kinase	Get druggable targets OG5_128597	All targets in OG5_128597
Schistosoma japonicum	IPR000494,EGF receptor, L domain,domain-containing	Get druggable targets OG5_128597	All targets in OG5_128597
Echinococcus multilocularis	epidermal growth factor receptor	Get druggable targets OG5_128597	All targets in OG5_128597

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	leukotriene A4 hydrolase	611 aa	508 aa	22.8 %
Trypanosoma brucei	mitogen-activated protein kinase 5	mitogen-activated protein kinase 1	360 aa	361 aa	33.2 %
Brugia malayi	steroid hormone receptor	vitamin D (1,25- dihydroxyvitamin D3) receptor	427 aa	416 aa	24.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	axis inhibition protein axin	0.0055	0.0766	0.0854
Echinococcus multilocularis	regulator of G protein signaling 3	0.0055	0.0766	0.0854
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0027	0.0241	0.1661
Brugia malayi	ORL1-like opioid receptor	0.0249	0.4335	0.4335
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Echinococcus multilocularis	neuropeptide Y receptor	0.0249	0.4335	0.4828
Schistosoma mansoni	tyrosine kinase	0.0046	0.0601	0.0601
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	fibroinase	0.0027	0.0241	0.0224
Onchocerca volvulus		0.0249	0.4335	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus multilocularis	epidermal growth factor receptor	0.0181	0.3085	0.3437
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0249	0.4335	0.4828
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Schistosoma mansoni	biogenic amine receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trichomonas vaginalis	conserved hypothetical protein	0.0055	0.0766	0.5285
Echinococcus granulosus	biogenic amine 5HT receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0249	0.4335	0.4828
Echinococcus multilocularis	neuropeptide Y receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	TK protein kinase	0.0042	0.0519	0.0503
Schistosoma mansoni	histamine h1 receptor	0.0249	0.4335	0.4335
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Echinococcus granulosus	epidermal growth factor receptor	0.0098	0.155	0.1727
Brugia malayi	hypothetical protein	0.0055	0.0766	0.0766
Echinococcus multilocularis	g protein coupled receptor	0.0249	0.4335	0.4828
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0249	0.4335	1
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trichomonas vaginalis	CMGC family protein kinase	0.0063	0.0902	0.6223
Entamoeba histolytica	cysteine proteinase, putative	0.0018	0.0077	0.1
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0249	0.4335	0.4335
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus granulosus	orexin receptor type 2	0.0249	0.4335	0.4828
Schistosoma mansoni	opsin-like receptor	0.0249	0.4335	0.4335
Leishmania major	dihydrofolate reductase-thymidylate synthase	0.0195	0.333	1
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Onchocerca volvulus		0.0249	0.4335	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0042	0.0519	0.0578
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0241	0.0241
Trypanosoma brucei	mitogen activated protein kinase 4, putative	0.0063	0.0902	0.271
Echinococcus multilocularis	neuropeptide receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Schistosoma mansoni	amine GPCR	0.0249	0.4335	0.4335
Loa Loa (eye worm)	TK protein kinase	0.0038	0.0435	0.0419
Onchocerca volvulus		0.0018	0.0077	0.0138
Plasmodium falciparum	M1-family alanyl aminopeptidase	0.0015	0.0017	0.0051
Brugia malayi	regulator of G-protein signaling rgs-7	0.0055	0.0766	0.0766
Echinococcus granulosus	serotonin receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0055	0.0766	0.0766
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Onchocerca volvulus		0.0249	0.4335	1
Echinococcus granulosus	fmrfamide receptor	0.0249	0.4335	0.4828
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus granulosus	epidermal growth factor receptor	0.0181	0.3085	0.3437
Loa Loa (eye worm)	SRC-1	0.0046	0.0601	0.0584
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0015	0.0017	0.0051
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	0.0195	0.333	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Schistosoma mansoni	axis inhibition protein axin	0.0055	0.0766	0.0766
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0249	0.4335	0.4335
Onchocerca volvulus		0.0027	0.0241	0.0518
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Plasmodium vivax	vivapain-2	0.0027	0.0241	0.0723
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0249	0.4335	0.4335
Brugia malayi	hypothetical protein	0.0055	0.0766	0.0766
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	neuropeptide Y receptor	0.0249	0.4335	0.4828
Brugia malayi	AKH receptor	0.0249	0.4335	0.4335
Toxoplasma gondii	cathepsin CPL	0.0027	0.0241	0.0675
Echinococcus multilocularis	sex peptide receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus granulosus	neuropeptide FF receptor 2	0.0249	0.4335	0.4828
Brugia malayi	neuropeptide F receptor	0.0249	0.4335	0.4335
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0249	0.4335	0.4828
Schistosoma mansoni	hypothetical protein	0.0249	0.4335	0.4335
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0249	0.4335	0.4828
Onchocerca volvulus		0.0027	0.0241	0.0518
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0027	0.0241	0.0268
Schistosoma mansoni	growth hormone secretagogue receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Schistosoma mansoni	opsin-like receptor	0.0249	0.4335	0.4335
Brugia malayi	hypothetical protein	0.0128	0.2106	0.2106
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0241	0.0241
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.0279	0.4881	0.4881
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0046	0.0601	0.0669
Loa Loa (eye worm)	TYRA-2 protein	0.0249	0.4335	0.4325
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	tm gpcr rhodopsin	0.0249	0.4335	0.4828
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Schistosoma mansoni	neuropeptide receptor	0.0249	0.4335	0.4335
Onchocerca volvulus		0.0027	0.0241	0.0518
Schistosoma mansoni	regulator of G protein signaling 17 19 20 (rgs17 19 20)	0.0055	0.0766	0.0766
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus multilocularis	cysteine protease	0.0027	0.0241	0.0268
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Schistosoma mansoni	myosin xvIII	0.0249	0.4335	0.4335
Brugia malayi	Melatonin receptor type 1A	0.0249	0.4335	0.4335
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0059	0.0828	0.0922
Brugia malayi	hypothetical protein	0.0093	0.145	0.145
Brugia malayi	Serotonin receptor	0.0249	0.4335	0.4335
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0249	0.4335	0.4828
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0249	0.4335	0.4828
Brugia malayi	G-protein coupled receptor	0.0249	0.4335	0.4335
Schistosoma mansoni	cytosol alanyl aminopeptidase (M01 family)	0.0015	0.0017	0.0017
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.0015	0.0017	0.0051
Echinococcus granulosus	g protein coupled receptor	0.0249	0.4335	0.4828
Trichomonas vaginalis	CMGC family protein kinase	0.0063	0.0902	0.6223
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0249	0.4335	0.4335
Onchocerca volvulus		0.0249	0.4335	1
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	tyrosine kinase	0.0042	0.0519	0.0578
Onchocerca volvulus		0.0249	0.4335	1
Schistosoma mansoni	tyrosine kinase	0.0059	0.0828	0.0828
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0015	0.0017	0.0017
Schistosoma mansoni	neuropeptide F-like receptor	0.0249	0.4335	0.4335
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Echinococcus granulosus	dro:myosuppressin receptor	0.0249	0.4335	0.4828
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0027	0.0241	0.0723
Trypanosoma cruzi	aminopeptidase, putative	0.0015	0.0017	0.0051
Trypanosoma cruzi	metallo-peptidase, Clan MA(E) Family M1	0.0015	0.0017	0.0051
Brugia malayi	G protein-coupled receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus multilocularis	Regulator of G protein signaling 20	0.0055	0.0766	0.0854
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0249	0.4335	0.4335
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0249	0.4335	0.4828
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0018	0.0077	0.0528
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0249	0.4335	0.4828
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0249	0.4335	0.4828
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Trypanosoma brucei	aminopeptidase, putative	0.0015	0.0017	0.0051
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0249	0.4335	0.4335
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.0279	0.4881	0.5437
Brugia malayi	cathepsin L-like precursor	0.0018	0.0077	0.0077
Loa Loa (eye worm)	cysteine protease	0.0027	0.0241	0.0224
Brugia malayi	Cathepsin L-like precursor	0.0018	0.0077	0.0077
Echinococcus granulosus	expressed protein	0.0055	0.0766	0.0854
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Brugia malayi	MAP kinase sur-1	0.0063	0.0902	0.0902
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0249	0.4335	0.4828
Echinococcus granulosus	allatostatin A receptor	0.0249	0.4335	0.4828
Mycobacterium ulcerans	thymidylate synthase	0.0195	0.333	1
Brugia malayi	follicle stimulating hormone receptor	0.0249	0.4335	0.4335
Echinococcus multilocularis	expressed protein	0.0055	0.0766	0.0854
Entamoeba histolytica	hypothetical protein	0.0055	0.0766	1
Loa Loa (eye worm)	hypothetical protein	0.0027	0.0241	0.0224
Brugia malayi	PXA domain containing protein	0.0055	0.0766	0.0766
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0027	0.0241	0.0268
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0241	0.0723
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0249	0.4335	0.4828
Schistosoma mansoni	hypothetical protein	0.0249	0.4335	0.4335
Onchocerca volvulus		0.0249	0.4335	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0249	0.4335	0.4325
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase, putative	0.0093	0.145	0.4354
Schistosoma mansoni	hypothetical protein	0.0249	0.4335	0.4335
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0027	0.0241	0.0723
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0046	0.0601	0.0669
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0027	0.0241	0.0723
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0249	0.4335	0.4828
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0249	0.4335	0.4335
Schistosoma mansoni	regulator of G protein signaling	0.0055	0.0766	0.0766
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0046	0.0601	0.0669
Echinococcus multilocularis	neuropeptides capa receptor	0.0249	0.4335	0.4828
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0027	0.0241	0.0268
Echinococcus multilocularis	neuropeptide receptor A26	0.0249	0.4335	0.4828
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0249	0.4335	0.4335
Schistosoma mansoni	opsin-like receptor	0.0249	0.4335	0.4335
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0048	0.0635	0.0708
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0063	0.0902	0.271
Entamoeba histolytica	cysteine protease, putative	0.0027	0.0241	0.3142
Echinococcus granulosus	mitogen activated protein kinase	0.0063	0.0902	0.1005
Onchocerca volvulus		0.0249	0.4335	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0241	0.0723
Echinococcus granulosus	neuropeptide receptor A26	0.0249	0.4335	0.4828
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0249	0.4335	0.4828
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0018	0.0077	0.0528
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0249	0.4335	0.4828
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	0.0195	0.333	1
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0015	0.0017	0.0118
Schistosoma mansoni	hypothetical protein	0.0249	0.4335	0.4335
Echinococcus granulosus	mitogen activated protein kinase 3	0.0063	0.0902	0.1005
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Echinococcus granulosus	tm gpcr rhodopsin	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus multilocularis	fmrfamide receptor	0.0249	0.4335	0.4828
Onchocerca volvulus		0.0249	0.4335	1
Onchocerca volvulus	Cathepsin F homolog	0.0027	0.0241	0.0518
Schistosoma mansoni	biogenic amine receptor	0.0249	0.4335	0.4335
Brugia malayi	Dopamine receptor protein 1	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Mycobacterium leprae	PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE)	0.0195	0.333	0.5
Onchocerca volvulus		0.0249	0.4335	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0249	0.4335	0.4325
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Leishmania major	mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440	0.0063	0.0902	0.2672
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0042	0.0519	0.0578
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Brugia malayi	G protein-coupled receptor F59B2.13	0.0249	0.4335	0.4335
Echinococcus multilocularis	mitogen activated protein kinase	0.0063	0.0902	0.1005
Brugia malayi	Peptidase family M1 containing protein	0.0015	0.0017	0.0017
Trypanosoma cruzi	aminopeptidase, putative	0.0015	0.0017	0.0051
Brugia malayi	Probable G protein-coupled receptor kinase F19C6.1, putative	0.0501	0.8978	0.8978
Schistosoma mansoni	regulator of G protein signaling	0.0055	0.0766	0.0766
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0046	0.0601	0.0669
Schistosoma mansoni	axis inhibition protein axin	0.0055	0.0766	0.0766
Giardia lamblia	Kinase, CMGC MAPK	0.0063	0.0902	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Brugia malayi	larval opioid receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0766	0.075
Onchocerca volvulus		0.0027	0.0241	0.0518
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0046	0.0601	0.0669
Echinococcus granulosus	regulator of G protein signaling 3	0.0055	0.0766	0.0854
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0249	0.4335	0.4335
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.0015	0.0017	0.0051
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0046	0.0601	0.0669
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0249	0.4335	0.4325
Schistosoma mansoni	regulator of G protein signaling	0.0055	0.0766	0.0766
Echinococcus multilocularis	g-protein coupled receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0181	0.3085	0.3073
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0766	0.075
Schistosoma mansoni	neuropeptide receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	neuropeptides capa receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	tyrosine protein kinase Src42A	0.004	0.0477	0.0531
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Onchocerca volvulus		0.0027	0.0241	0.0518
Brugia malayi	hypothetical protein	0.0015	0.0017	0.0017
Brugia malayi	regulator of G-protein signaling egl-10	0.0055	0.0766	0.0766
Onchocerca volvulus		0.0249	0.4335	1
Toxoplasma gondii	CMGC kinase, MAPK family (ERK) MAPK-1	0.0063	0.0902	0.2672
Echinococcus multilocularis	Peptidase M1, membrane alanine aminopeptidase, N terminal	0.0015	0.0017	0.0019
Echinococcus multilocularis	thymidylate synthase	0.0195	0.333	0.3709
Echinococcus multilocularis	cysteine protease	0.0027	0.0241	0.0268
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0046	0.0601	0.0669
Echinococcus multilocularis	serotonin receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0042	0.0519	0.0578
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trypanosoma cruzi	mitogen activated protein kinase 4, putative	0.0063	0.0902	0.271
Schistosoma mansoni	regulator of G protein signaling	0.0055	0.0766	0.0766
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	TK/INSR protein kinase	0.0059	0.0828	0.0812
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0249	0.4335	0.4335
Echinococcus granulosus	neuropeptide receptor	0.0249	0.4335	0.4828
Entamoeba histolytica	cysteine proteinase, putative	0.0027	0.0241	0.3142
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0077	0.006
Echinococcus multilocularis	orexin receptor type 2	0.0249	0.4335	0.4828
Brugia malayi	PXA domain containing protein	0.0055	0.0766	0.0766
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Schistosoma mansoni	serine/threonine protein kinase	0.0063	0.0902	0.0902
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0046	0.0601	0.0669
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus multilocularis	G protein coupled receptor kinase 6	0.0501	0.8978	1
Echinococcus granulosus	Regulator of G protein signaling 20	0.0055	0.0766	0.0854
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus multilocularis		0.0056	0.0771	0.0859
Echinococcus granulosus	neuropeptide receptor	0.0249	0.4335	0.4828
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	0.0195	0.333	1
Brugia malayi	TATA binding protein associated factor	0.0015	0.0017	0.0017
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Trichomonas vaginalis	conserved hypothetical protein	0.0055	0.0766	0.5285
Brugia malayi	Dopamine receptor	0.0249	0.4335	0.4335
Echinococcus granulosus	tyrosine protein kinase Blk	0.0042	0.0519	0.0578
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	7tm_1 domain containing protein	0.0249	0.4335	0.4828
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Onchocerca volvulus	Cathepsin L homolog	0.0027	0.0241	0.0518
Echinococcus granulosus	neuropeptides capa receptor	0.0249	0.4335	0.4828
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Onchocerca volvulus		0.0027	0.0241	0.0518
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0046	0.0601	0.0669
Schistosoma mansoni	amine GPCR	0.0249	0.4335	0.4335
Trypanosoma cruzi	puromycin-sensitive aminopeptidase-like protein, putative	0.0015	0.0017	0.0051
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Echinococcus multilocularis	axis inhibition protein axin	0.0055	0.0766	0.0854
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	0.0195	0.333	1
Brugia malayi	GnHR receptor homolog	0.0249	0.4335	0.4335
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.0015	0.0017	0.0051
Brugia malayi	thymidylate synthase	0.0195	0.333	0.333
Loa Loa (eye worm)	PXA domain-containing protein	0.0055	0.0766	0.075
Trichomonas vaginalis	conserved hypothetical protein	0.0093	0.145	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Plasmodium vivax	vivapain-2	0.0027	0.0241	0.0723
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Onchocerca volvulus		0.0249	0.4335	1
Schistosoma mansoni	neuropeptide receptor	0.0249	0.4335	0.4335
Schistosoma mansoni	neuropeptide F-like receptor	0.0249	0.4335	0.4335
Echinococcus granulosus	neuropeptide Y receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Schistosoma mansoni	neuropeptide f receptor 76f	0.0249	0.4335	0.4335
Loa Loa (eye worm)	G-protein coupled receptor	0.0249	0.4335	0.4325
Echinococcus multilocularis	serotonin receptor	0.0249	0.4335	0.4828
Brugia malayi	Peptidase family M1 containing protein	0.0015	0.0017	0.0017
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0249	0.4335	0.4335
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0249	0.4335	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0249	0.4335	0.4335
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Trichomonas vaginalis	conserved hypothetical protein	0.0055	0.0766	0.5285
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0249	0.4335	0.4335
Schistosoma mansoni	serine/threonine protein kinase	0.0557	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0557	1	1
Trichomonas vaginalis	regulator of G protein signaling 5, rgs5, putative	0.0055	0.0766	0.5285
Schistosoma mansoni	tyrosine kinase	0.0098	0.155	0.155
Brugia malayi	putative neuropeptide receptor NPR1	0.0249	0.4335	0.4335
Trypanosoma brucei	Aminopeptidase M1, putative	0.0015	0.0017	0.0051
Brugia malayi	G-protein coupled receptor	0.0249	0.4335	0.4335
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.004	0.0477	0.0531
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Schistosoma mansoni	tyrosine kinase	0.0046	0.0601	0.0601
Brugia malayi	RE15519p	0.0249	0.4335	0.4335
Echinococcus multilocularis	neuropeptides capa receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0766	0.075
Echinococcus granulosus	7TM GPCR rhodopsin	0.0249	0.4335	0.4828
Brugia malayi	neuropeptide F receptor	0.0249	0.4335	0.4335
Brugia malayi	Peptidase family M1 containing protein	0.0015	0.0017	0.0017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus granulosus	cathepsin l1	0.0027	0.0241	0.0268
Schistosoma mansoni	cathepsin F (C01 family)	0.0027	0.0241	0.0241
Echinococcus granulosus	g protein coupled receptor	0.0249	0.4335	0.4828
Schistosoma mansoni	tyrosine kinase	0.0098	0.155	0.155
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	G protein signaling regulator EGL-10	0.0055	0.0766	0.075
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	aminopeptidase N	0.0015	0.0017	0.0019
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0241	0.0241
Schistosoma mansoni	neuropeptide receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	ctsf protein	0.0027	0.0241	0.0224
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	0.0195	0.333	1
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	hypothetical protein	0.0249	0.4335	0.4828
Schistosoma mansoni	Tata binding protein associated factor (M01 family)	0.0015	0.0017	0.0017
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0241	0.0723
Schistosoma mansoni	tyrosine kinase	0.0181	0.3085	0.3085
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus multilocularis	g protein coupled receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Mycobacterium tuberculosis	Probable thymidylate synthase ThyA (ts) (TSASE)	0.0195	0.333	1
Schistosoma mansoni	z-protein (S1r protein)	0.0055	0.0766	0.0766
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Echinococcus multilocularis	cathepsin L cysteine protease	0.0027	0.0241	0.0268
Schistosoma mansoni	tyrosine kinase	0.0096	0.1508	0.1508
Schistosoma mansoni	cathepsin F (C01 family)	0.0027	0.0241	0.0241
Echinococcus multilocularis	dro:myosuppressin receptor	0.0249	0.4335	0.4828
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Entamoeba histolytica	hypothetical protein	0.0055	0.0766	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0046	0.0601	0.0669
Echinococcus multilocularis	G protein coupled receptor 139	0.0249	0.4335	0.4828
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Entamoeba histolytica	hypothetical protein	0.0055	0.0766	1
Echinococcus multilocularis	fmrfamide receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	regulator of G protein signaling 3	0.0055	0.0766	0.0854
Echinococcus multilocularis	neuropeptide receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0027	0.0241	0.0224
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus multilocularis	epidermal growth factor receptor	0.0098	0.155	0.1727
Trichomonas vaginalis	conserved hypothetical protein	0.0055	0.0766	0.5285
Loa Loa (eye worm)	G protein-coupled receptor kinase 1	0.0501	0.8978	0.8976
Trichomonas vaginalis	conserved hypothetical protein	0.0055	0.0766	0.5285
Echinococcus granulosus	tm gpcr rhodopsin	0.0249	0.4335	0.4828
Brugia malayi	Protein kinase domain containing protein	0.0059	0.0828	0.0828
Loa Loa (eye worm)	melatonin receptor type 1A	0.0249	0.4335	0.4325
Schistosoma mansoni	amine GPCR	0.0249	0.4335	0.4335
Plasmodium falciparum	M1-family alanyl aminopeptidase, putative	0.0015	0.0017	0.0051
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0046	0.0601	0.0669
Entamoeba histolytica	aminopeptidase, putative	0.0015	0.0017	0.0223
Schistosoma mansoni	tyrosine kinase	0.0059	0.0828	0.0828
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Loa Loa (eye worm)	G-protein coupled receptor	0.0249	0.4335	0.4325
Echinococcus granulosus	[G-protein-coupledreceptor] kinase	0.0501	0.8978	1
Schistosoma mansoni	amine GPCR	0.0249	0.4335	0.4335
Schistosoma mansoni	tyrosine kinase	0.0096	0.1508	0.1508
Echinococcus granulosus	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus multilocularis	beta adrenergic receptor kinase	0.0057	0.0801	0.0892
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0249	0.4335	0.4325
Schistosoma mansoni	biogenic amine receptor	0.0249	0.4335	0.4335
Schistosoma mansoni	regulator of G protein signaling 3 rgs3	0.0055	0.0766	0.0766
Loa Loa (eye worm)	RGS-3 protein	0.0055	0.0766	0.075
Brugia malayi	Serotonin receptor	0.0249	0.4335	0.4335
Onchocerca volvulus		0.0249	0.4335	1
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.0057	0.0801	0.0785
Onchocerca volvulus		0.0249	0.4335	1
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	leukotriene A 4 hydrolase	0.0279	0.4881	0.5437
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0077	0.006
Brugia malayi	SRC-1	0.0046	0.0601	0.0601
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Loa Loa (eye worm)	CMGC/MAPK/ERK1 protein kinase	0.0063	0.0902	0.0887
Schistosoma mansoni	serine/threonine protein kinase	0.0057	0.0801	0.0801
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0015	0.0017	0.0118
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0249	0.4335	0.4828
Onchocerca volvulus		0.0249	0.4335	1
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trypanosoma brucei	protein kinase, putative	0.0063	0.0902	0.271
Echinococcus multilocularis	allatostatin A receptor	0.0249	0.4335	0.4828
Brugia malayi	hypothetical protein	0.0015	0.0017	0.0017
Echinococcus multilocularis	g protein coupled receptor	0.0249	0.4335	0.4828
Echinococcus multilocularis	somatostatin receptor	0.0249	0.4335	0.4828
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0015	0.0017	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0766	0.075
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0059	0.0828	0.0922
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Schistosoma mansoni	cathepsin F (C01 family)	0.0018	0.0077	0.0077
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Echinococcus granulosus	beta-adrenergic receptor kinase	0.0057	0.0801	0.0892
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0249	0.4335	0.4828
Echinococcus multilocularis	A kinase anchor protein 10, mitochondrial	0.0055	0.0766	0.0854
Trypanosoma brucei	Aminopeptidase M1, putative	0.0015	0.0017	0.0051
Brugia malayi	Furin-like cysteine rich region family protein	0.0181	0.3085	0.3085
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0046	0.0601	0.0669
Schistosoma mansoni	regulator of G protein signaling	0.0055	0.0766	0.0766
Trypanosoma cruzi	mitogen activated protein kinase 2, putative	0.0063	0.0902	0.271
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Leishmania major	cysteine peptidase A (CPA)	0.0027	0.0241	0.0675
Entamoeba histolytica	cysteine proteinase, putative	0.0027	0.0241	0.3142
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0038	0.0435	0.0485
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0241	0.0241
Echinococcus multilocularis	mitogen activated protein kinase 3	0.0063	0.0902	0.1005
Echinococcus multilocularis	regulator of G protein signaling 3	0.0055	0.0766	0.0854
Leishmania major	cathepsin L-like protease	0.0027	0.0241	0.0675
Trypanosoma cruzi	Aminopeptidase M1, putative	0.0015	0.0017	0.0051
Brugia malayi	A-kinase anchor protein 10, precursor	0.0055	0.0766	0.0766
Loa Loa (eye worm)	neuropeptide F receptor	0.0249	0.4335	0.4325
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Echinococcus granulosus	thymidylate synthase	0.0195	0.333	0.3709
Echinococcus granulosus	insulin receptor	0.0059	0.0828	0.0922
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus granulosus	cathepsin l1	0.0018	0.0077	0.0085
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0249	0.4335	0.4335
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Onchocerca volvulus		0.0249	0.4335	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.0027	0.0241	0.0268
Echinococcus multilocularis	regulator of G protein signaling 7	0.0055	0.0766	0.0854
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0249	0.4335	0.4828
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus granulosus	sex peptide receptor	0.0249	0.4335	0.4828
Schistosoma mansoni	tyrosine kinase	0.0096	0.1508	0.1508
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0027	0.0241	0.0224
Onchocerca volvulus	Cathepsin L homolog	0.0027	0.0241	0.0518
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Schistosoma mansoni	bifunctional dihydrofolate reductase-thymidylate synthase	0.0195	0.333	0.333
Onchocerca volvulus		0.0249	0.4335	1
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0249	0.4335	0.4335
Echinococcus multilocularis	aminopeptidase N	0.0015	0.0017	0.0019
Echinococcus multilocularis	regulator of G protein signaling 7	0.0055	0.0766	0.0854
Brugia malayi	Papain family cysteine protease containing protein	0.0027	0.0241	0.0241
Schistosoma mansoni	adenoreceptor	0.0249	0.4335	0.4335
Echinococcus granulosus	somatostatin receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	G protein coupled receptor 139	0.0249	0.4335	0.4828
Trichomonas vaginalis	CMGC family protein kinase	0.0063	0.0902	0.6223
Schistosoma mansoni	aminopeptidase A (M01 family)	0.0015	0.0017	0.0017
Echinococcus granulosus	biogenic amine 5HT receptor	0.0249	0.4335	0.4828
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0055	0.0766	0.0766
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Loa Loa (eye worm)	AGC/GRK/GRK protein kinase	0.0501	0.8978	0.8976
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0042	0.0519	0.0578
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0766	0.075
Schistosoma mansoni	amine GPCR	0.0249	0.4335	0.4335
Echinococcus multilocularis	insulin receptor	0.0059	0.0828	0.0922
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Onchocerca volvulus		0.0027	0.0241	0.0518
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0249	0.4335	0.4828
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.0279	0.4881	0.4872
Brugia malayi	sulfakinin receptor protein	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Onchocerca volvulus		0.0195	0.333	0.7672
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	g-protein coupled receptor	0.0249	0.4335	0.4828
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0046	0.0601	0.0669
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Plasmodium vivax	M1-family alanyl aminopeptidase, putative	0.0015	0.0017	0.0051
Trichomonas vaginalis	conserved hypothetical protein	0.0055	0.0766	0.5285
Echinococcus multilocularis	axis inhibition protein axin	0.0055	0.0766	0.0854
Echinococcus granulosus	axis inhibition protein axin	0.0055	0.0766	0.0854
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0015	0.0017	0.0051
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0249	0.4335	0.4335
Brugia malayi	Regulator of G protein signaling domain containing protein	0.0055	0.0766	0.0766
Echinococcus granulosus	neuropeptide s receptor	0.0249	0.4335	0.4828
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0077	0.006
Echinococcus granulosus	A kinase anchor protein 10 mitochondrial	0.0055	0.0766	0.0854
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0027	0.0241	0.1661
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0046	0.0601	0.0669
Echinococcus granulosus	regulator of G protein signaling 7	0.0055	0.0766	0.0854
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0018	0.0077	0.023
Onchocerca volvulus		0.0249	0.4335	1
Entamoeba histolytica	protein kinase, putative	0.0038	0.0435	0.5678
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0249	0.4335	0.4325
Brugia malayi	putative neuropeptide receptor	0.0249	0.4335	0.4335
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0249	0.4335	0.4335
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Trichomonas vaginalis	CMGC family protein kinase	0.0063	0.0902	0.6223
Echinococcus multilocularis	neuropeptide s receptor	0.0249	0.4335	0.4828
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0018	0.0077	0.0077
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0249	0.4335	0.4828
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0249	0.4335	0.4335
Echinococcus granulosus	g protein coupled receptor	0.0249	0.4335	0.4828
Trypanosoma cruzi	cruzipain precursor, putative	0.0027	0.0241	0.0723
Trypanosoma cruzi	cysteine peptidase, putative	0.0027	0.0241	0.0723
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0241	0.0241
Leishmania major	mitogen activated protein kinase, putative,map kinase, putative	0.0063	0.0902	0.2672
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0249	0.4335	0.4335
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0249	0.4335	0.4335
Loa Loa (eye worm)	thymidylate synthase	0.0195	0.333	0.3318
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0098	0.155	0.1727
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0046	0.0601	0.0669
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0249	0.4335	0.4828
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0046	0.0601	0.0669
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0249	0.4335	0.4828
Echinococcus granulosus	regulator of G protein signaling 7	0.0055	0.0766	0.0854
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0249	0.4335	0.4335
Brugia malayi	Cathepsin L-like precursor	0.0027	0.0241	0.0241
Brugia malayi	Dopamine receptor protein 2	0.0249	0.4335	0.4335
Brugia malayi	hypothetical protein	0.0249	0.4335	0.4335
Trypanosoma cruzi	mitogen-activated protein kinase 11, putative	0.0063	0.0902	0.271
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0027	0.0241	0.0268
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0027	0.0241	0.1661
Loa Loa (eye worm)	neuropeptide F receptor	0.0249	0.4335	0.4325
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0027	0.0241	0.0723
Echinococcus granulosus	tyrosine protein kinase HCK	0.0038	0.0435	0.0485
Loa Loa (eye worm)	hypothetical protein	0.0249	0.4335	0.4325
Schistosoma mansoni	serine/threonine protein kinase	0.0057	0.0801	0.0801
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0766	0.075
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0015	0.0017	0.0019
Brugia malayi	Cathepsin L-like precursor	0.0018	0.0077	0.0077
Brugia malayi	protein-tyrosine kinase	0.0042	0.0519	0.0519
Echinococcus multilocularis	regulator of G protein signaling	0.0055	0.0766	0.0854

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (functional)	= 94.59 %	Growth inhibition of human MDA-MB-468 cells assessed as cell growth at 10'-5 M after 48 hrs by sulforhodamine B assay relative to control	ChEMBL.	24125851
Ki (binding)	= 2.59 uM	Inhibition of human leukotriene A-4 hydrolase	ChEMBL.	24125851
Ki (binding)	= 3.67 uM	Inhibition of human MAPK1	ChEMBL.	24125851
Ki (binding)	= 4.66 uM	Inhibition of human vitamin D3 receptor	ChEMBL.	24125851
Ki (binding)	= 10.91 uM	Inhibition of human thymidylate synthase	ChEMBL.	24125851
Ki (binding)	= 16.77 uM	Inhibition of human EGFR	ChEMBL.	24125851
Ki (binding)	= 21.87 uM	Inhibition of human cathepsin K	ChEMBL.	24125851
Ki (binding)	= 34.3 uM	Inhibition of human SRC	ChEMBL.	24125851

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2437297

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 1788914