Detailed information for compound 1800570

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 642.732 | Formula: C32H50O13
  • H donors: 8 H acceptors: 9 LogP: 0.6 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 3
  • SMILES: OC[C@@H]1O[C@@H](O[C@@]23CC[C@@H]4[C@@](C2)(CC3=C)CC[C@H]2[C@@]4(C)CCC[C@@]2(C)C(=O)O)[C@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@@H](CO)[C@H]([C@@H]([C@@H]1O)O)O
  • InChi: 1S/C32H50O13/c1-15-11-31-9-5-18-29(2,7-4-8-30(18,3)28(40)41)19(31)6-10-32(15,14-31)45-27-25(23(38)21(36)17(13-34)43-27)44-26-24(39)22(37)20(35)16(12-33)42-26/h16-27,33-39H,1,4-14H2,2-3H3,(H,40,41)/t16-,17-,18-,19-,20+,21+,22-,23-,24-,25-,26-,27-,29+,30+,31+,32-/m0/s1
  • InChiKey: OMHUCGDTACNQEX-QETSLKRESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0047 0.0298
Leishmania major hypothetical protein, conserved 0.0029 0.0092 0.1089
Trypanosoma brucei unspecified product 0.0022 0.0047 0.0728
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0376 0.6054
Loa Loa (eye worm) PHD-finger family protein 0.0033 0.0121 0.1557
Onchocerca volvulus Serine\/threonine kinase homolog 0.0108 0.0602 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0327 0.4214
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.005 0.0637
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.003 0.003
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0121 0.0291
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.0774 1
Loa Loa (eye worm) cysteine protease 0.0019 0.003 0.0377
Brugia malayi hypothetical protein 0.0029 0.0092 0.1182
Schistosoma mansoni hypothetical protein 0.0077 0.0405 0.0376
Leishmania major cathepsin L-like protease 0.0073 0.0376 0.6054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0047 0.0728
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.0602 1
Leishmania major DNA polymerase kappa, putative 0.0022 0.0047 0.0298
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0105 0.1349
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0166 0.0166
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0048 0.0018
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0077 0.0405 0.5227
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.0048 0.0607
Brugia malayi MH2 domain containing protein 0.0135 0.0774 1
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.005 0.002
Echinococcus granulosus dna polymerase eta 0.0022 0.0047 0.0047
Treponema pallidum hypothetical protein 0.0648 0.408 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Loa Loa (eye worm) hypothetical protein 0.0019 0.003 0.0377
Brugia malayi jmjC domain containing protein 0.0044 0.019 0.245
Schistosoma mansoni cpg binding protein 0.0065 0.0327 0.0298
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0027 0.0079 0.5
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Leishmania major DNA polymerase eta, putative 0.0022 0.0047 0.0298
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0108 0.0602 0.7769
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0048 0.0048
Schistosoma mansoni cpg binding protein 0.0069 0.0351 0.0322
Brugia malayi latrophilin 2 splice variant baaae 0.0077 0.0405 0.5227
Entamoeba histolytica serine/threonine protein kinase, putative 0.0108 0.0602 1
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0376 0.6054
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0079 0.0726
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0092 0.1089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.0185 0.0185
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0036 0.0138 0.0138
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.005 0.005
Schistosoma mansoni kinase 0.0055 0.026 0.0231
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.0048 0.0607
Echinococcus multilocularis cpg binding protein 0.0069 0.0351 0.0351
Brugia malayi Cathepsin L-like precursor 0.0019 0.003 0.0377
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0067 0.0335 0.5342
Entamoeba histolytica hypothetical protein 0.0022 0.0048 0.0312
Loa Loa (eye worm) hypothetical protein 0.0057 0.0275 0.3538
Echinococcus granulosus PHD finger protein rhinoceros 0.0033 0.0121 0.0121
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.0048 0.0048
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0092 0.022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.003 0.0377
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0047 0.0047
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.0048 0.0048
Loa Loa (eye worm) ctsf protein 0.0019 0.003 0.0377
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0092 0.022
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0018
Schistosoma mansoni hypothetical protein 0.0928 0.5889 0.5877
Schistosoma mansoni serine/threonine protein kinase 0.0108 0.0602 0.0574
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0109 0.0609 0.0609
Trypanosoma brucei polo-like protein kinase 0.0108 0.0602 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0081 0.0051
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0108 0.0602 1
Brugia malayi PXA domain containing protein 0.0022 0.0048 0.0607
Loa Loa (eye worm) hypothetical protein 0.0095 0.0519 0.6692
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Echinococcus multilocularis dnaJ subfamily B 0.0928 0.5889 0.5889
Echinococcus granulosus cpg binding protein 0.0069 0.0351 0.0351
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0048 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0774 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.003 0.0467
Brugia malayi Bromodomain containing protein 0.0033 0.0121 0.1557
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0648 0.408 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.019 0.245
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0048 0.0048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.003 0.0377
Brugia malayi hypothetical protein 0.0019 0.0027 0.0332
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0648 0.408 1
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0765
Echinococcus multilocularis microtubule associated protein 2 0.1566 1 1
Echinococcus granulosus dnaJ subfamily B 0.0928 0.5889 0.5889
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0037 0.0037
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0387 0.6235
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0047 0.0752
Schistosoma mansoni hypothetical protein 0.0036 0.0138 0.0108
Onchocerca volvulus Alhambra homolog 0.0033 0.0121 0.1597
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Schistosoma mansoni axis inhibition protein axin 0.0022 0.0048 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0037 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Brugia malayi Cathepsin L-like precursor 0.0019 0.003 0.0377
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0047 0.0298
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0607
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0607
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0048 0.0607
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0607
Entamoeba histolytica hypothetical protein 0.0022 0.0048 0.0312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0047 0.0298
Giardia lamblia Kinase, PLK 0.0108 0.0602 1
Echinococcus granulosus axis inhibition protein axin 0.0022 0.0048 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Brugia malayi CXXC zinc finger family protein 0.0065 0.0327 0.4214
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0079 0.1259
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.003 0.003
Leishmania major cathepsin L-like protease 0.0073 0.0376 0.6054
Loa Loa (eye worm) hypothetical protein 0.0029 0.0092 0.1182
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0636 0.8209
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0048 0.0018
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0074 0.0387 0.0387
Echinococcus multilocularis cysteine protease 0.0019 0.003 0.003
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.003 0.0067
Echinococcus multilocularis L aminoadipate semialdehyde 0.0095 0.0519 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0765
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0079 0.5
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0047 0.0597
Brugia malayi Calcitonin receptor-like protein seb-1 0.0113 0.0636 0.8209
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0074 0.0387 0.4986
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0074 0.0387 0.4986
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0074 0.0387 0.6235
Giardia lamblia PHD finger protein 15 0.0033 0.0121 0.1339
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0092 0.0926
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.003 0.0467
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0047 0.0298
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0648 0.408 1
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0047 0.0298
Echinococcus granulosus lysine specific demethylase 5A 0.0044 0.019 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0047 0.0728
Brugia malayi hypothetical protein 0.0022 0.0048 0.0607
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0251 0.4149
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0607
Brugia malayi serine/threonine-protein kinase plk-2 0.0108 0.0602 0.7769
Echinococcus multilocularis dna polymerase eta 0.0022 0.0047 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.005 0.0637
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.0048 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Echinococcus granulosus transcription factor Dp 1 0.0043 0.0185 0.0185
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0121 0.1358
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0607
Loa Loa (eye worm) histone methyltransferase 0.002 0.0037 0.0464
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0079 0.0726
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0036 0.0138 0.1766
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0765
Trypanosoma cruzi polo-like protein kinase, putative 0.0108 0.0602 1
Plasmodium vivax vivapain-2 0.0019 0.003 0.0067
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.0048 0.0018
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0036 0.0138 0.0138
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0095 0.0519 0.6692
Loa Loa (eye worm) RGS-3 protein 0.0022 0.0048 0.0607
Entamoeba histolytica hypothetical protein 0.0022 0.0048 0.0312
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0376 0.6054
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0387 0.6235
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0095 0.0519 0.049
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0047 0.0752
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0018
Entamoeba histolytica hypothetical protein 0.0027 0.0079 0.0854
Brugia malayi hypothetical protein 0.0022 0.0048 0.0607
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0048 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0092 0.1089
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.005 0.002
Echinococcus multilocularis jumonji domain containing protein 0.0046 0.0205 0.0205
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.019 0.0161
Brugia malayi Cathepsin L-like precursor 0.0019 0.003 0.0377
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0048 0.0048
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0092 0.1483
Trypanosoma cruzi cruzipain precursor, putative 0.0073 0.0376 0.6054
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0047 0.0597
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Loa Loa (eye worm) PXA domain-containing protein 0.0022 0.0048 0.0607
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0092 0.022
Echinococcus multilocularis PHD finger protein rhinoceros 0.0033 0.0121 0.0121
Echinococcus multilocularis GPCR, family 2 0.0036 0.0138 0.0138
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0108 0.0602 0.0602
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0648 0.408 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0033 0.0121 0.1358
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0047 0.0298
Schistosoma mansoni DNA polymerase eta 0.0022 0.0047 0.0017
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0027 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0036 0.0138 0.0108
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0607
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0765
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0108 0.0602 0.0602
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0047 0.0597
Echinococcus granulosus expressed protein 0.0426 0.2653 0.2653
Loa Loa (eye worm) hypothetical protein 0.0033 0.0121 0.1557
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.003 0.003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0047 0.0047
Loa Loa (eye worm) latrophilin receptor protein 2 0.0036 0.0138 0.1766
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.003 0.003
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0074 0.0387 0.0358
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0047 0.0728
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0011 0.0011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0011 0.0011
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.0048 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Echinococcus multilocularis expressed protein 0.0426 0.2653 0.2653
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0138 0.0798 0.077
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0251 0.4149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Echinococcus granulosus jumonji domain containing protein 0.0046 0.0205 0.0205
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.003 0.0377
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Schistosoma mansoni hypothetical protein 0.0036 0.0138 0.0108
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.0048 0.0048
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.005 0.002
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.0048 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0074 0.0387 0.6402
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Brugia malayi Latrophilin receptor protein 2 0.0036 0.0138 0.1766
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.005 0.0637
Onchocerca volvulus 0.0065 0.0327 0.5191
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.0048 0.0048
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0074 0.0387 0.6235
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0047 0.0047
Schistosoma mansoni cpg binding protein 0.0069 0.0351 0.0322
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.0048 0.0048
Schistosoma mansoni jumonji/arid domain-containing protein 0.0044 0.019 0.0161
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0074 0.0387 0.0387
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0048 0.0607
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.003 0.003
Brugia malayi Cathepsin L-like precursor 0.0019 0.003 0.0377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Schistosoma mansoni hypothetical protein 0.0036 0.0138 0.0108
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0036 0.0138 0.0138
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0079 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Echinococcus granulosus dna polymerase kappa 0.0022 0.0047 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0765
Plasmodium vivax vivapain-2 0.0019 0.003 0.0067
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0047 0.0728
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0048 0.0018
Loa Loa (eye worm) hypothetical protein 0.0022 0.0047 0.0597
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0276 0.4297
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.003 0.003
Schistosoma mansoni jumonji domain containing protein 0.0087 0.0465 0.0436
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.0048 0.0048
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0079 0.0854
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0048 0.0765
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0048 0.0048
Brugia malayi jmjC domain containing protein 0.0109 0.0609 0.7866
Toxoplasma gondii histone lysine methyltransferase SET1 0.0123 0.0703 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0033 0.0121 0.0092
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0047 0.0017
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0648 0.408 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.005 0.005
Onchocerca volvulus 0.0095 0.0519 0.8544
Brugia malayi PHD-finger family protein 0.0033 0.0121 0.1557
Echinococcus granulosus cathepsin l1 0.0019 0.003 0.003
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.003 0.0067
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0113 0.0636 0.8209
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.0048 0.0607
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.003 0.0067
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0113 0.0636 0.8209
Brugia malayi Cathepsin L-like precursor 0.0019 0.003 0.0377
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0047 0.0298
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0027 0.0079 0.0079
Schistosoma mansoni microtubule-associated protein tau 0.1566 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0109 0.0609 0.0609
Echinococcus granulosus L aminoadipate semialdehyde 0.0095 0.0519 0.0519
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0018
Echinococcus multilocularis cysteine protease 0.0019 0.003 0.003
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0048 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Loa Loa (eye worm) fibroinase 0.0019 0.003 0.0377
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0027 0.0079 0.0079
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0022 0.0048 0.0765
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Echinococcus multilocularis peregrin 0.0033 0.0121 0.0121
Echinococcus granulosus peregrin 0.0033 0.0121 0.0121
Brugia malayi Cathepsin L-like precursor 0.0019 0.003 0.0377
Loa Loa (eye worm) hypothetical protein 0.0036 0.0138 0.1766
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0047 0.0017
Brugia malayi PXA domain containing protein 0.0022 0.0048 0.0607
Schistosoma mansoni hypothetical protein 0.0033 0.0121 0.0092
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0376 0.6229
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0047 0.0728
Plasmodium falciparum phd finger protein, putative 0.0033 0.0121 0.0291
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0079 0.0187
Leishmania major cathepsin L-like protease 0.0073 0.0376 0.6054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0048 0.0607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.003 0.0467
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.003 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0108 0.0602 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0036 0.0138 0.0138
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.035 0.451
Echinococcus granulosus GPCR family 2 0.0036 0.0138 0.0138
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0048 0.0018

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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