Detailed information for compound 1801420

Basic information

Technical information
  • TDR Targets ID: 1801420
  • Name: 1,1,1-trifluoro-3-octylsulfanylbutan-2-one
  • MW: 270.355 | Formula: C12H21F3OS
  • H donors: 0 H acceptors: 1 LogP: 5.56 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCSC(C(=O)C(F)(F)F)C
  • InChi: 1S/C12H21F3OS/c1-3-4-5-6-7-8-9-17-10(2)11(16)12(13,14)15/h10H,3-9H2,1-2H3
  • InChiKey: RFOPWAAQSSPJGC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,1,1-trifluoro-3-octylsulfanyl-butan-2-one
  • 1,1,1-trifluoro-3-(octylthio)butan-2-one
  • 112240-74-1

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus pyruvate kinase 0.0051 0.0935 0.0935
Onchocerca volvulus Pyruvate kinase homolog 0.0099 0.2412 0.5885
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Toxoplasma gondii pyruvate kinase PyKII 0.0051 0.0935 0.0686
Schistosoma mansoni intermediate filament proteins 0.0026 0.0183 0.0183
Echinococcus granulosus lamin 0.0026 0.0183 0.0183
Brugia malayi TAR-binding protein 0.0066 0.1399 0.1434
Echinococcus multilocularis cyclin dependent kinase 9 0.0062 0.1269 0.1269
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.8811 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.3842 0.4055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Loa Loa (eye worm) haspin protein kinase 0.0341 0.9853 1
Echinococcus granulosus serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0783 0.0783
Schistosoma mansoni hypothetical protein 0.0345 1 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0453 0.0464
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus dual specificity 0.018 0.49 0.49
Schistosoma mansoni hypothetical protein 0.0345 1 1
Echinococcus multilocularis dual specificity 0.0264 0.7486 0.7486
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0264 0.7486 0.8414
Loa Loa (eye worm) pyruvate kinase 0.0099 0.2412 0.2448
Giardia lamblia Kinase, CMGC DYRK 0.0264 0.7486 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.49 0.5321
Brugia malayi hypothetical protein 0.0337 0.9754 1
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis dual specificity 0.0264 0.7486 0.7486
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0704 0.0301
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0062 0.1269 0.1288
Schistosoma mansoni pyruvate kinase 0.0051 0.0935 0.0935
Echinococcus granulosus pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0119 0.3039 0.3115
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0783 0.0783
Brugia malayi beta-lactamase family protein 0.0035 0.0453 0.0464
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0026 0.0183 0.0186
Echinococcus multilocularis musashi 0.0026 0.0183 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Leishmania major chitinase 0.0075 0.1684 0.1473
Loa Loa (eye worm) microfilarial chitinase 0.0073 0.1622 0.1646
Brugia malayi Cell division protein kinase 2 0.0062 0.1269 0.1301
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0783 0.0783
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0062 0.1269 0.0977
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis pyruvate kinase 0.0051 0.0935 0.0935
Onchocerca volvulus Putative endochitinase 0.0075 0.1684 0.4109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.4347 0.6722
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.3842 0.4055
Onchocerca volvulus 0.0153 0.4098 1
Entamoeba histolytica hypothetical protein 0.0058 0.1171 0.0924
Brugia malayi GSG2 0.0337 0.9754 1
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.003 0.0296 0.0303
Loa Loa (eye worm) RNA binding protein 0.0066 0.1399 0.142
Echinococcus granulosus pyruvate kinase 0.0051 0.0935 0.0935
Mycobacterium ulcerans hypothetical protein 0.0162 0.4347 1
Onchocerca volvulus 0.0035 0.0453 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Mycobacterium ulcerans chitinase/cellulase 0.0064 0.1344 0.2289
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.018 0.49 0.5321
Entamoeba histolytica protein kinase, putative 0.0264 0.7486 1
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0264 0.7486 0.8414
Onchocerca volvulus Huntingtin homolog 0.0119 0.3035 0.7407
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0183 0.0186
Loa Loa (eye worm) hypothetical protein 0.0119 0.3039 0.3084
Echinococcus multilocularis dual specificity 0.018 0.49 0.49
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0453 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0264 0.7486 1
Entamoeba histolytica cell division protein kinase 2, putative 0.0062 0.1269 0.1065
Echinococcus multilocularis pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.7486 0.7486
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Onchocerca volvulus Pyruvate kinase homolog 0.0099 0.2412 0.5885
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0704 0.0301
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0783 0.0783
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.8811 1
Loa Loa (eye worm) TAR-binding protein 0.0066 0.1399 0.142
Loa Loa (eye worm) beta-lactamase 0.0035 0.0453 0.046
Schistosoma mansoni protein kinase 0.0062 0.1269 0.1269
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Loa Loa (eye worm) hypothetical protein 0.0119 0.3035 0.308
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.1269 0.1065
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.1399 0.142
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0783 0.0783
Trypanosoma brucei pyruvate kinase 1 0.0099 0.2412 0.2343
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0264 0.7486 0.8414
Onchocerca volvulus Pyruvate kinase homolog 0.0099 0.2412 0.5885
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi pyruvate kinase 0.0021 0.0017 0.0018
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0119 0.3039 0.3039
Trypanosoma cruzi pyruvate kinase 2, putative 0.0099 0.2412 0.2343
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Schistosoma mansoni hypothetical protein 0.0037 0.0528 0.0528
Schistosoma mansoni lamin 0.0026 0.0183 0.0183
Echinococcus multilocularis tar DNA binding protein 0.0066 0.1399 0.1399
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0528 0.0528
Plasmodium vivax pyruvate kinase, putative 0.0099 0.2412 0.7575
Echinococcus granulosus pyruvate kinase 0.0051 0.0935 0.0935
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0995 0.0648
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.018 0.49 0.4974
Loa Loa (eye worm) hypothetical protein 0.0119 0.3039 0.3084
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) haspin protein kinase 0.0337 0.9754 0.99
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.8811 1
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0062 0.1269 0.0977
Entamoeba histolytica hypothetical protein 0.018 0.49 0.6284
Trypanosoma brucei protein kinase, putative 0.0062 0.1269 0.0977
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Mycobacterium leprae Probable pyruvate kinase PykA 0.0099 0.2412 1
Giardia lamblia Pyruvate kinase 0.0099 0.2412 0.2254
Loa Loa (eye worm) hypothetical protein 0.0064 0.1344 0.1364
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0119 0.3039 0.3039
Echinococcus granulosus dual specificity 0.0264 0.7486 0.7486
Trichomonas vaginalis pyruvate kinase, putative 0.0099 0.2412 0.2785
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.49 0.5321
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0062 0.1269 0.0977
Entamoeba histolytica chitinase, putative 0.0075 0.1684 0.1661
Echinococcus multilocularis lamin 0.0026 0.0183 0.0183
Trypanosoma cruzi pyruvate kinase 2, putative 0.0099 0.2412 0.2343
Brugia malayi pyruvate kinase, muscle isozyme 0.0021 0.0017 0.0018
Onchocerca volvulus 0.0119 0.3039 0.7415
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Mycobacterium tuberculosis Possible chitinase 0.0064 0.1344 0.1539
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0704 0.0301
Plasmodium vivax pyruvate kinase 2, putative 0.0051 0.0935 0.1865
Echinococcus granulosus serine:threonine protein kinase NLK 0.0062 0.1269 0.1269
Echinococcus multilocularis pyruvate kinase 0.0051 0.0935 0.0935
Trypanosoma brucei pyruvate kinase 1, putative 0.0099 0.2412 0.2343
Toxoplasma gondii pyruvate kinase PyK1 0.0099 0.2412 0.2785
Echinococcus granulosus pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Entamoeba histolytica pyruvate kinase, putative 0.0069 0.1494 0.1388
Onchocerca volvulus Putative endochitinase 0.0075 0.1684 0.4109
Echinococcus multilocularis lamin dm0 0.0026 0.0183 0.0183
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0453 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0026 0.0168 0.0171
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0062 0.1269 0.1161
Loa Loa (eye worm) pyruvate kinase 0.0021 0.0017 0.0017
Echinococcus multilocularis pyruvate kinase 0.0078 0.1772 0.1772
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Chlamydia trachomatis pyruvate kinase 0.0099 0.2412 0.5
Loa Loa (eye worm) hypothetical protein 0.0153 0.4098 0.4159
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0783 0.0795
Loa Loa (eye worm) pyruvate kinase 0.0099 0.2412 0.2448
Echinococcus multilocularis pyruvate kinase 0.0099 0.2412 0.2412
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.3842 0.4055
Giardia lamblia Kinase, CAMK CAMKL 0.0062 0.1269 0.051
Loa Loa (eye worm) haspin protein kinase 0.0337 0.9754 0.99
Schistosoma mansoni hypothetical protein 0.0058 0.1171 0.1171
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.1399 0.1434
Brugia malayi cyclin-dependent kinase 7 homolog 0.0062 0.1269 0.1301
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.8811 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Entamoeba histolytica protein kinase domain containing protein 0.0264 0.7486 1
Schistosoma mansoni serine/threonine protein kinase 0.018 0.49 0.49
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0062 0.1269 0.0977
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus cyclin dependent kinase 9 0.0062 0.1269 0.1269
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0264 0.7486 0.7674
Entamoeba histolytica protein kinase, putative 0.018 0.49 0.6284
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0062 0.1269 0.1269
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Plasmodium falciparum pyruvate kinase 0.0099 0.2412 0.7019
Onchocerca volvulus 0.0035 0.0453 0.1105
Brugia malayi hypothetical protein 0.0119 0.3035 0.3111
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi RNA binding protein 0.0066 0.1399 0.1434
Loa Loa (eye worm) pyruvate kinase-PB 0.0069 0.1494 0.1516
Brugia malayi beta-lactamase family protein 0.0035 0.0453 0.0464
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0062 0.1269 0.1288
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis geminin 0.0345 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0783 0.0783
Echinococcus multilocularis dual specificity 0.0264 0.7486 0.7486
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus dual specificity 0.0264 0.7486 0.7486
Brugia malayi Protein kinase domain containing protein 0.018 0.49 0.5024
Schistosoma mansoni hypothetical protein 0.0119 0.3039 0.3039
Echinococcus granulosus intermediate filament protein 0.0026 0.0183 0.0183
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.018 0.49 0.5321
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0183 0.0188
Toxoplasma gondii hypothetical protein 0.0119 0.3039 0.3676
Schistosoma mansoni serine/threonine kinase 0.0062 0.1269 0.1269
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Onchocerca volvulus Putative endochitinase 0.0084 0.1962 0.4787
Trichomonas vaginalis pyruvate kinase, putative 0.0099 0.2412 0.2785
Onchocerca volvulus Putative endochitinase 0.0084 0.1962 0.4787
Brugia malayi endochitinase 0.0075 0.1684 0.1726
Onchocerca volvulus 0.0035 0.0453 0.1105
Loa Loa (eye worm) chitinase I 0.0075 0.1684 0.1709
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0058 0.1171 0.1171
Loa Loa (eye worm) hypothetical protein 0.0119 0.3035 0.308
Onchocerca volvulus Huntingtin homolog 0.0119 0.3035 0.7407
Echinococcus multilocularis hypothetical protein 0.0058 0.1171 0.1171
Trichomonas vaginalis protein kinase atmrk1, putative 0.0062 0.1269 0.1161
Brugia malayi Protein kinase domain containing protein 0.0062 0.1269 0.1301
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Entamoeba histolytica protein kinase domain containing protein 0.018 0.49 0.6284
Brugia malayi endochitinase 0.0084 0.1962 0.2011
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0264 0.7486 0.7598
Trichomonas vaginalis serine/threonine kinase, putative 0.0062 0.1269 0.1161
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0062 0.1269 0.3157
Mycobacterium ulcerans pyruvate kinase 0.0099 0.2412 0.503
Loa Loa (eye worm) hypothetical protein 0.0176 0.4802 0.4874
Plasmodium falciparum conserved protein, unknown function 0.0119 0.3039 1
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0783 0.0783
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Onchocerca volvulus 0.0119 0.3039 0.7415
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0783 0.0803
Leishmania major pyruvate kinase 0.0099 0.2412 0.2343
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi hypothetical protein 0.0037 0.0528 0.0541
Plasmodium falciparum MO15-related protein kinase 0.0062 0.1269 0.1589
Plasmodium vivax hypothetical protein, conserved 0.0119 0.3039 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus tar DNA binding protein 0.0066 0.1399 0.1399
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0099 0.2412 0.2448
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.1269 0.1269
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0062 0.1269 0.0977
Entamoeba histolytica protein kinase, putative 0.018 0.49 0.6284
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0099 0.2412 0.3381
Brugia malayi beta-lactamase 0.0035 0.0453 0.0464
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Leishmania major pyruvate kinase 0.0099 0.2412 0.2343
Mycobacterium ulcerans chitinase/cellulase 0.0064 0.1344 0.2289
Echinococcus granulosus serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1516
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Onchocerca volvulus 0.0026 0.0183 0.0446
Giardia lamblia Kinase, CAMK CAMKL 0.0062 0.1269 0.051
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.6246 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0453 0.046
Onchocerca volvulus Putative endochitinase 0.0084 0.1962 0.4787
Loa Loa (eye worm) cuticular endochitinase 0.0075 0.1684 0.1709
Schistosoma mansoni pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Schistosoma mansoni lamin 0.0026 0.0183 0.0183
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0062 0.1269 0.1269
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0062 0.1269 0.1269
Brugia malayi Endochitinase 0.0084 0.1962 0.2011
Echinococcus multilocularis pyruvate kinase 0.0051 0.0935 0.0935
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0528 0.0528
Toxoplasma gondii hypothetical protein 0.0049 0.0899 0.0635
Brugia malayi intermediate filament protein 0.0026 0.0183 0.0188
Loa Loa (eye worm) hypothetical protein 0.0176 0.4802 0.4874
Echinococcus granulosus lamin dm0 0.0026 0.0183 0.0183
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0062 0.1269 0.3157
Echinococcus granulosus mitogen activated protein kinase 15 0.0062 0.1269 0.1269
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Giardia lamblia Kinase, CAMK CAMKL 0.0062 0.1269 0.051
Loa Loa (eye worm) pyruvate kinase 0.0099 0.2412 0.2448
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0183 0.0186
Schistosoma mansoni hypothetical protein 0.0337 0.9754 0.9754
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Leishmania major serine/threonine kinase-like protein, putative 0.0062 0.1269 0.0977
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0704 0.0301
Brugia malayi hypothetical protein 0.0153 0.4098 0.4201
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Schistosoma mansoni pyruvate kinase 0.0099 0.2412 0.2412
Brugia malayi Pyruvate kinase, muscle isozyme 0.0099 0.2412 0.2472
Echinococcus granulosus serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Brugia malayi Pyruvate kinase, M2 isozyme 0.0099 0.2412 0.2472
Onchocerca volvulus 0.0026 0.0183 0.0446
Echinococcus granulosus dual specificity 0.0264 0.7486 0.7486

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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