Detailed information for compound 1804349

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 284.381 | Formula: C13H23F3OS
  • H donors: 0 H acceptors: 1 LogP: 6 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCC(SC(C(=O)C(F)(F)F)C)C
  • InChi: 1S/C13H23F3OS/c1-4-5-6-7-8-9-10(2)18-11(3)12(17)13(14,15)16/h10-11H,4-9H2,1-3H3
  • InChiKey: JPVJIIVJDFUZFA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi endochitinase 0.0075 0.1684 0.1726
Onchocerca volvulus 0.0035 0.0453 0.1105
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) chitinase I 0.0075 0.1684 0.1709
Echinococcus multilocularis hypothetical protein 0.0058 0.1171 0.1171
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0058 0.1171 0.1171
Onchocerca volvulus Huntingtin homolog 0.0119 0.3035 0.7407
Loa Loa (eye worm) hypothetical protein 0.0119 0.3035 0.308
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Trichomonas vaginalis protein kinase atmrk1, putative 0.0062 0.1269 0.1161
Brugia malayi Protein kinase domain containing protein 0.0062 0.1269 0.1301
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.018 0.49 0.5321
Echinococcus granulosus intermediate filament protein 0.0026 0.0183 0.0183
Schistosoma mansoni serine/threonine kinase 0.0062 0.1269 0.1269
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0183 0.0188
Toxoplasma gondii hypothetical protein 0.0119 0.3039 0.3676
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Onchocerca volvulus Putative endochitinase 0.0084 0.1962 0.4787
Trichomonas vaginalis pyruvate kinase, putative 0.0099 0.2412 0.2785
Onchocerca volvulus Putative endochitinase 0.0084 0.1962 0.4787
Echinococcus multilocularis geminin 0.0345 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0783 0.0783
Echinococcus multilocularis dual specificity 0.0264 0.7486 0.7486
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0453 0.0453
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi Protein kinase domain containing protein 0.018 0.49 0.5024
Schistosoma mansoni hypothetical protein 0.0119 0.3039 0.3039
Echinococcus granulosus dual specificity 0.0264 0.7486 0.7486
Brugia malayi hypothetical protein 0.0119 0.3035 0.3111
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) pyruvate kinase-PB 0.0069 0.1494 0.1516
Brugia malayi RNA binding protein 0.0066 0.1399 0.1434
Brugia malayi beta-lactamase family protein 0.0035 0.0453 0.0464
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0062 0.1269 0.1288
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0062 0.1269 0.0977
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus cyclin dependent kinase 9 0.0062 0.1269 0.1269
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0264 0.7486 0.7674
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0062 0.1269 0.1269
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Entamoeba histolytica protein kinase, putative 0.018 0.49 0.6284
Plasmodium falciparum pyruvate kinase 0.0099 0.2412 0.7019
Onchocerca volvulus 0.0035 0.0453 0.1105
Schistosoma mansoni hypothetical protein 0.0058 0.1171 0.1171
Loa Loa (eye worm) haspin protein kinase 0.0337 0.9754 0.99
Brugia malayi cyclin-dependent kinase 7 homolog 0.0062 0.1269 0.1301
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.1399 0.1434
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.8811 1
Entamoeba histolytica protein kinase domain containing protein 0.0264 0.7486 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Schistosoma mansoni serine/threonine protein kinase 0.018 0.49 0.49
Chlamydia trachomatis pyruvate kinase 0.0099 0.2412 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0153 0.4098 0.4159
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0783 0.0795
Loa Loa (eye worm) pyruvate kinase 0.0099 0.2412 0.2448
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.3842 0.4055
Echinococcus multilocularis pyruvate kinase 0.0099 0.2412 0.2412
Giardia lamblia Kinase, CAMK CAMKL 0.0062 0.1269 0.051
Onchocerca volvulus Putative endochitinase 0.0075 0.1684 0.4109
Echinococcus multilocularis lamin dm0 0.0026 0.0183 0.0183
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0453 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0453 0.0453
Loa Loa (eye worm) pyruvate kinase 0.0021 0.0017 0.0017
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0026 0.0168 0.0171
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis pyruvate kinase 0.0078 0.1772 0.1772
Schistosoma mansoni hypothetical protein 0.0337 0.9754 0.9754
Leishmania major serine/threonine kinase-like protein, putative 0.0062 0.1269 0.0977
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0704 0.0301
Brugia malayi hypothetical protein 0.0153 0.4098 0.4201
Schistosoma mansoni pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Brugia malayi Pyruvate kinase, muscle isozyme 0.0099 0.2412 0.2472
Echinococcus granulosus dual specificity 0.0264 0.7486 0.7486
Brugia malayi Pyruvate kinase, M2 isozyme 0.0099 0.2412 0.2472
Onchocerca volvulus 0.0026 0.0183 0.0446
Echinococcus granulosus serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Toxoplasma gondii hypothetical protein 0.0049 0.0899 0.0635
Echinococcus granulosus lamin dm0 0.0026 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0176 0.4802 0.4874
Brugia malayi intermediate filament protein 0.0026 0.0183 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus mitogen activated protein kinase 15 0.0062 0.1269 0.1269
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0062 0.1269 0.3157
Giardia lamblia Kinase, CAMK CAMKL 0.0062 0.1269 0.051
Loa Loa (eye worm) pyruvate kinase 0.0099 0.2412 0.2448
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0183 0.0186
Schistosoma mansoni pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Loa Loa (eye worm) cuticular endochitinase 0.0075 0.1684 0.1709
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0062 0.1269 0.1269
Schistosoma mansoni lamin 0.0026 0.0183 0.0183
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0062 0.1269 0.1269
Brugia malayi Endochitinase 0.0084 0.1962 0.2011
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis pyruvate kinase 0.0051 0.0935 0.0935
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0528 0.0528
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Onchocerca volvulus 0.0026 0.0183 0.0446
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0069 0.1494 0.1516
Echinococcus granulosus serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Giardia lamblia Kinase, CAMK CAMKL 0.0062 0.1269 0.051
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.6246 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0453 0.046
Onchocerca volvulus Putative endochitinase 0.0084 0.1962 0.4787
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0099 0.2412 0.2448
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.1269 0.1269
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0062 0.1269 0.0977
Entamoeba histolytica protein kinase, putative 0.018 0.49 0.6284
Brugia malayi beta-lactamase 0.0035 0.0453 0.0464
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0099 0.2412 0.3381
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Leishmania major pyruvate kinase 0.0099 0.2412 0.2343
Mycobacterium ulcerans chitinase/cellulase 0.0064 0.1344 0.2289
Plasmodium falciparum MO15-related protein kinase 0.0062 0.1269 0.1589
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Plasmodium vivax hypothetical protein, conserved 0.0119 0.3039 1
Echinococcus granulosus tar DNA binding protein 0.0066 0.1399 0.1399
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Leishmania major pyruvate kinase 0.0099 0.2412 0.2343
Onchocerca volvulus 0.0119 0.3039 0.7415
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0783 0.0803
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi hypothetical protein 0.0037 0.0528 0.0541
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Entamoeba histolytica protein kinase domain containing protein 0.018 0.49 0.6284
Brugia malayi endochitinase 0.0084 0.1962 0.2011
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0264 0.7486 0.7598
Trichomonas vaginalis serine/threonine kinase, putative 0.0062 0.1269 0.1161
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0062 0.1269 0.3157
Mycobacterium ulcerans pyruvate kinase 0.0099 0.2412 0.503
Loa Loa (eye worm) hypothetical protein 0.0176 0.4802 0.4874
Plasmodium falciparum conserved protein, unknown function 0.0119 0.3039 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0783 0.0783
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Onchocerca volvulus Pyruvate kinase homolog 0.0099 0.2412 0.5885
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0704 0.0301
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0783 0.0783
Entamoeba histolytica cell division protein kinase 2, putative 0.0062 0.1269 0.1065
Echinococcus multilocularis pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni serine/threonine protein kinase 0.0264 0.7486 0.7486
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Onchocerca volvulus 0.0035 0.0453 0.1105
Mycobacterium ulcerans hypothetical protein 0.0162 0.4347 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Mycobacterium ulcerans chitinase/cellulase 0.0064 0.1344 0.2289
Entamoeba histolytica protein kinase, putative 0.0264 0.7486 1
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.018 0.49 0.5321
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0183 0.0186
Onchocerca volvulus Huntingtin homolog 0.0119 0.3035 0.7407
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0264 0.7486 0.8414
Loa Loa (eye worm) hypothetical protein 0.0119 0.3039 0.3084
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0264 0.7486 1
Echinococcus multilocularis dual specificity 0.018 0.49 0.49
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0453 0.0453
Onchocerca volvulus Putative endochitinase 0.0075 0.1684 0.4109
Mycobacterium tuberculosis Conserved hypothetical protein 0.0162 0.4347 0.6722
Onchocerca volvulus 0.0153 0.4098 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.3842 0.4055
Brugia malayi GSG2 0.0337 0.9754 1
Entamoeba histolytica hypothetical protein 0.0058 0.1171 0.0924
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.003 0.0296 0.0303
Loa Loa (eye worm) RNA binding protein 0.0066 0.1399 0.142
Echinococcus granulosus pyruvate kinase 0.0051 0.0935 0.0935
Brugia malayi beta-lactamase family protein 0.0035 0.0453 0.0464
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0528 0.0528
Echinococcus multilocularis musashi 0.0026 0.0183 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Loa Loa (eye worm) hypothetical protein 0.0026 0.0183 0.0186
Loa Loa (eye worm) microfilarial chitinase 0.0073 0.1622 0.1646
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Leishmania major chitinase 0.0075 0.1684 0.1473
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0783 0.0783
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0062 0.1269 0.0977
Brugia malayi Cell division protein kinase 2 0.0062 0.1269 0.1301
Echinococcus multilocularis pyruvate kinase 0.0051 0.0935 0.0935
Echinococcus multilocularis dual specificity 0.0264 0.7486 0.7486
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0704 0.0301
Schistosoma mansoni pyruvate kinase 0.0051 0.0935 0.0935
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0062 0.1269 0.1288
Echinococcus granulosus pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0119 0.3039 0.3115
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0783 0.0783
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus dual specificity 0.018 0.49 0.49
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0264 0.7486 0.8414
Echinococcus multilocularis dual specificity 0.0264 0.7486 0.7486
Schistosoma mansoni hypothetical protein 0.0345 1 1
Loa Loa (eye worm) pyruvate kinase 0.0099 0.2412 0.2448
Giardia lamblia Kinase, CMGC DYRK 0.0264 0.7486 1
Brugia malayi hypothetical protein 0.0337 0.9754 1
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.49 0.5321
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Toxoplasma gondii pyruvate kinase PyKII 0.0051 0.0935 0.0686
Onchocerca volvulus Pyruvate kinase homolog 0.0099 0.2412 0.5885
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Echinococcus granulosus pyruvate kinase 0.0051 0.0935 0.0935
Brugia malayi TAR-binding protein 0.0066 0.1399 0.1434
Echinococcus granulosus lamin 0.0026 0.0183 0.0183
Schistosoma mansoni intermediate filament proteins 0.0026 0.0183 0.0183
Echinococcus multilocularis cyclin dependent kinase 9 0.0062 0.1269 0.1269
Leishmania major mitochondrial DNA polymerase beta 0.0307 0.8811 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.046
Loa Loa (eye worm) haspin protein kinase 0.0341 0.9853 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.3842 0.4055
Schistosoma mansoni hypothetical protein 0.0345 1 1
Echinococcus granulosus serine:threonine protein kinase haspin 0.0337 0.9754 0.9754
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0783 0.0783
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0453 0.0464
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Toxoplasma gondii pyruvate kinase PyK1 0.0099 0.2412 0.2785
Trypanosoma brucei pyruvate kinase 1, putative 0.0099 0.2412 0.2343
Echinococcus multilocularis pyruvate kinase 0.0051 0.0935 0.0935
Echinococcus granulosus pyruvate kinase 0.0099 0.2412 0.2412
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Entamoeba histolytica pyruvate kinase, putative 0.0069 0.1494 0.1388
Onchocerca volvulus 0.0119 0.3039 0.7415
Brugia malayi pyruvate kinase, muscle isozyme 0.0021 0.0017 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Mycobacterium tuberculosis Possible chitinase 0.0064 0.1344 0.1539
Echinococcus granulosus serine:threonine protein kinase NLK 0.0062 0.1269 0.1269
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0704 0.0301
Plasmodium vivax pyruvate kinase 2, putative 0.0051 0.0935 0.1865
Loa Loa (eye worm) hypothetical protein 0.0064 0.1344 0.1364
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0119 0.3039 0.3039
Echinococcus granulosus dual specificity 0.0264 0.7486 0.7486
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis pyruvate kinase, putative 0.0099 0.2412 0.2785
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.49 0.5321
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0062 0.1269 0.0977
Entamoeba histolytica chitinase, putative 0.0075 0.1684 0.1661
Trypanosoma cruzi pyruvate kinase 2, putative 0.0099 0.2412 0.2343
Echinococcus multilocularis lamin 0.0026 0.0183 0.0183
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Mycobacterium leprae Probable pyruvate kinase PykA 0.0099 0.2412 1
Giardia lamblia Pyruvate kinase 0.0099 0.2412 0.2254
Plasmodium vivax pyruvate kinase, putative 0.0099 0.2412 0.7575
Echinococcus multilocularis tar DNA binding protein 0.0066 0.1399 0.1399
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0528 0.0528
Echinococcus granulosus pyruvate kinase 0.0051 0.0935 0.0935
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0995 0.0648
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.018 0.49 0.4974
Loa Loa (eye worm) hypothetical protein 0.0119 0.3039 0.3084
Loa Loa (eye worm) haspin protein kinase 0.0337 0.9754 0.99
Trichomonas vaginalis AGC family protein kinase 0.0062 0.1269 0.1161
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0062 0.1269 0.0977
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0307 0.8811 1
Trichomonas vaginalis CMGC family protein kinase 0.0062 0.1269 0.1161
Entamoeba histolytica hypothetical protein 0.018 0.49 0.6284
Trypanosoma brucei protein kinase, putative 0.0062 0.1269 0.0977
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161
Onchocerca volvulus Pyruvate kinase homolog 0.0099 0.2412 0.5885
Trypanosoma cruzi pyruvate kinase 2, putative 0.0099 0.2412 0.2343
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0119 0.3039 0.3039
Brugia malayi pyruvate kinase 0.0021 0.0017 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.0264 0.7486 1
Schistosoma mansoni hypothetical protein 0.0037 0.0528 0.0528
Schistosoma mansoni lamin 0.0026 0.0183 0.0183
Schistosoma mansoni tar DNA-binding protein 0.0066 0.1399 0.1399
Loa Loa (eye worm) hypothetical protein 0.0119 0.3035 0.308
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.1399 0.142
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.1269 0.1065
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0783 0.0783
Trypanosoma brucei pyruvate kinase 1 0.0099 0.2412 0.2343
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0264 0.7486 0.8414
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0307 0.8811 1
Loa Loa (eye worm) TAR-binding protein 0.0066 0.1399 0.142
Loa Loa (eye worm) beta-lactamase 0.0035 0.0453 0.046
Schistosoma mansoni protein kinase 0.0062 0.1269 0.1269
Trichomonas vaginalis CAMK family protein kinase 0.0062 0.1269 0.1161

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.