Detailed information for compound 188064

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 184.279 | Formula: C10H20N2O
  • H donors: 2 H acceptors: 1 LogP: 1.37 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H]1[C@H](CCCCC)N=C([C@@H]1O)N
  • InChi: 1S/C10H20N2O/c1-3-4-5-6-8-7(2)9(13)10(11)12-8/h7-9,13H,3-6H2,1-2H3,(H2,11,12)/t7-,8+,9-/m1/s1
  • InChiKey: DBFJQSOVVMBTEE-HRDYMLBCSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nitric oxide synthase 2, inducible Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0028 0.0193 0.0178
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis tensin 0.0409 0.3906 0.5888
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0279 0.2634 0.2623
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0079 0.0691 0.6999
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0149 0.0134
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0409 0.3906 0.5888
Echinococcus granulosus SH2 motif 0.0409 0.3906 0.5888
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0019
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0409 0.3906 0.5888
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0232 0.2176 0.3271
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Echinococcus granulosus protein tyrosine kinase 0.0279 0.2634 0.3964
Schistosoma mansoni nAChR subunit 0.0107 0.0959 0.0946
Loa Loa (eye worm) TK/FAK protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus tyrosine protein kinase Lyn 0.0687 0.6623 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0409 0.3906 0.3897
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Brugia malayi Variant SH3 domain containing protein 0.0409 0.3906 0.3897
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.2634 0.2623
Schistosoma mansoni adapter molecule crk 0.0409 0.3906 0.3897
Schistosoma mansoni acetylcholine receptor subunit beta 0.0107 0.0959 0.0946
Entamoeba histolytica serine/threonine kinase, putative 0.0279 0.2634 0.3964
Mycobacterium ulcerans DNA polymerase IV 0.0031 0.0223 0.2156
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0279 0.2634 0.3964
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0079 0.0691 0.0677
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Mycobacterium ulcerans aldehyde dehydrogenase 0.0032 0.0232 0.225
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Toxoplasma gondii exonuclease III APE 0.0014 0.0058 0.0218
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni cytochrome P450 reductase 0.0059 0.0494 0.048
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0368 0.0353
Onchocerca volvulus 0.0125 0.1134 0.1121
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) TK/EPH protein kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Echinococcus multilocularis integrin linked protein kinase 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Echinococcus granulosus nAChR subunit 0.0232 0.2176 0.3271
Plasmodium falciparum nitric oxide synthase, putative 0.0059 0.0494 0.1831
Loa Loa (eye worm) hypothetical protein 0.0028 0.0193 0.0178
Loa Loa (eye worm) hypothetical protein 0.0059 0.0494 0.048
Entamoeba histolytica tyrosin kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0279 0.2634 0.3964
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0015 0.0057
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0058 0.0162
Brugia malayi PAS domain containing protein 0.0026 0.017 0.0155
Onchocerca volvulus 0.0279 0.2634 0.2623
Brugia malayi bone morphogenetic protein type 1 receptor 0.0279 0.2634 0.2623
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.2634 0.2623
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK/EGFR protein kinase 0.0279 0.2634 0.2623
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK/INSR protein kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0059 0.0494 0.1831
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0232 0.2176 0.2164
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0279 0.2634 0.3964
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0223 0.2096 0.3149
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Brugia malayi flavodoxin family protein 0.0059 0.0494 0.048
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus granulosus receptor type guanylyl cyclase 0.0279 0.2634 0.3964
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Echinococcus multilocularis nAChR subunit 0.0232 0.2176 0.3271
Treponema pallidum flavodoxin 0.0023 0.0138 0.0395
Echinococcus multilocularis N chimaerin 0.0409 0.3906 0.5888
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0279 0.2634 0.3964
Trichomonas vaginalis protein kinase atn1, putative 0.0279 0.2634 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0279 0.2634 0.2623
Brugia malayi Protein kinase domain containing protein 0.0687 0.6623 0.6618
Trichomonas vaginalis AGC family protein kinase 0.0279 0.2634 1
Onchocerca volvulus 0.0107 0.0959 0.0946
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0059 0.0494 0.0726
Echinococcus granulosus tyrosine protein kinase HCK 0.0279 0.2634 0.3964
Brugia malayi excitatory GABA receptor EXP-1A 0.0232 0.2176 0.2164
Loa Loa (eye worm) SH2 domain-containing protein 0.0409 0.3906 0.3897
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0279 0.2634 1
Entamoeba histolytica serine/threonine kinase, putative 0.0279 0.2634 0.3964
Treponema pallidum fructose-bisphosphate aldolase 0.0223 0.2096 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Echinococcus granulosus jumonji domain containing 1A 0.0012 0.0034 0.0029
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0279 0.2634 1
Echinococcus granulosus growth factor receptor bound protein 2 0.0409 0.3906 0.5888
Brugia malayi jmjC domain containing protein 0.0012 0.0034 0.0019
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0409 0.3906 0.5888
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0279 0.2634 0.3964
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Mycobacterium ulcerans putative regulatory protein 0.0019 0.0104 0.0923
Echinococcus multilocularis tyrosine protein kinase HCK 0.0279 0.2634 0.3964
Brugia malayi hypothetical protein 0.0107 0.0959 0.0946
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0059 0.0494 0.0726
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Brugia malayi Variant SH3 domain containing protein 0.0409 0.3906 0.3897
Brugia malayi hypothetical protein 0.0107 0.0959 0.0946
Schistosoma mansoni cpg binding protein 0.0022 0.0131 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0074 0.0227
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0107 0.0959 0.0946
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0107 0.0959 0.0946
Giardia lamblia Fructose-bisphosphate aldolase 0.0223 0.2096 0.7944
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0107 0.0959 0.0946
Loa Loa (eye worm) hypothetical protein 0.1034 1 1
Schistosoma mansoni growth factor receptor-bound protein 0.0409 0.3906 0.3897
Echinococcus multilocularis insulin receptor 0.0279 0.2634 0.3964
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0409 0.3906 0.3897
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0409 0.3906 0.5888
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Brugia malayi RhoGAP domain containing protein 0.0409 0.3906 0.3897
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0279 0.2634 1
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0149 0.0512
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0232 0.2176 0.3271
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Onchocerca volvulus 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0032 0.0232 0.0329
Entamoeba histolytica hypothetical protein, conserved 0.0279 0.2634 0.3964
Loa Loa (eye worm) SH2 domain-containing protein 0.0409 0.3906 0.3897
Mycobacterium ulcerans aldehyde dehydrogenase 0.0032 0.0232 0.225
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0011 0.0025 0.001
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0279 0.2634 0.2623
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0014 0.0058 0.0064
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Giardia lamblia Hypothetical protein 0.0052 0.0429 0.158
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus multilocularis cpg binding protein 0.0023 0.0144 0.0195
Loa Loa (eye worm) hypothetical protein 0.0087 0.0764 0.075
Loa Loa (eye worm) SH2 domain-containing protein 0.0409 0.3906 0.3897
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica SH2 domain containing protein 0.0409 0.3906 0.5888
Schistosoma mansoni protein tyrosine kinase 0.0279 0.2634 0.2623
Giardia lamblia Kinase 0.0279 0.2634 1
Toxoplasma gondii flavodoxin domain-containing protein 0.0029 0.0204 0.0773
Schistosoma mansoni tensin 0.0409 0.3906 0.3897
Schistosoma mansoni nAChR subunit 0.0107 0.0959 0.0946
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Plasmodium vivax flavodoxin domain containing protein 0.0052 0.0429 0.158
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0279 0.2634 1
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0687 0.6623 1
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0279 0.2634 0.3964
Brugia malayi hypothetical protein 0.0107 0.0959 0.0946
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0059 0.0494 0.4961
Schistosoma mansoni hypothetical protein 0.0279 0.2634 0.2623
Leishmania major protein kinase, putative 0.0279 0.2634 1
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0193 0.0679
Echinococcus multilocularis epidermal growth factor receptor 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0927 0.8958 0.8956
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus glycine receptor subunit alpha 1 0.0232 0.2176 0.3271
Schistosoma mansoni DNA polymerase eta 0.0011 0.0025 0.001
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus multilocularis tyrosine protein kinase Srms 0.0687 0.6623 1
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus granulosus natriuretic peptide receptor 1 0.0279 0.2634 0.3964
Echinococcus multilocularis tyrosine protein kinase Abl 0.0687 0.6623 1
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) protein kinase domain-containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0279 0.2634 0.3964
Echinococcus granulosus tyrosine protein kinase Fyn 0.0687 0.6623 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Trichomonas vaginalis CAMK family protein kinase 0.0279 0.2634 1
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0037 0.0274 0.0259
Echinococcus granulosus tyrosine protein kinase csk 0.0279 0.2634 0.3964
Schistosoma mansoni serine/threonine RGC 0.0279 0.2634 0.2623
Echinococcus multilocularis tyrosine kinase 0.0687 0.6623 1
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0232 0.2176 0.3271
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus granulosus tyrosine protein kinase csk 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0028 0.0193 0.0269
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0232 0.2176 0.2164
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0014 0.0058 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0079 0.0691 0.6999
Brugia malayi integrin-linked kinase 0.0279 0.2634 0.2623
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0409 0.3906 0.3897
Echinococcus granulosus tyrosine protein kinase Fyn 0.0687 0.6623 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0687 0.6623 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0232 0.2176 0.2164
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0687 0.6623 1
Leishmania major DNA polymerase eta, putative 0.0011 0.0025 0.0039
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0409 0.3906 0.3897
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0028 0.0193 0.0679
Trypanosoma brucei protein kinase, putative 0.0279 0.2634 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Plasmodium falciparum tyrosine kinase-like protein 0.0279 0.2634 1
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0232 0.2176 0.2164
Schistosoma mansoni tensin-related 0.0409 0.3906 0.3897
Echinococcus granulosus expressed conserved protein 0.0409 0.3906 0.5888
Trypanosoma brucei DNA polymerase IV, putative 0.0026 0.0174 0.0608
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0232 0.2176 0.2164
Brugia malayi STAT protein, DNA binding domain containing protein 0.0409 0.3906 0.3897
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0023 0.0138 0.047
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Brugia malayi SH2 domain containing protein 0.0687 0.6623 0.6618
Echinococcus granulosus tyrosine protein kinase Src64B 0.0687 0.6623 1
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK/Met protein kinase 0.0279 0.2634 0.2623
Trypanosoma brucei DNA polymerase IV, putative 0.0031 0.0223 0.0796
Trypanosoma brucei Pseudokinase, putative 0.0279 0.2634 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0045 0.0356 0.0516
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.1034 1 1
Giardia lamblia Nitric oxide synthase, inducible 0.0052 0.0429 0.158
Brugia malayi Cation transporter family protein 0.0232 0.2176 0.2164
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0059 0.0494 0.1831
Echinococcus multilocularis ephrin type A receptor 4 A 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0409 0.3906 0.5888
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus multilocularis protein kinase 0.0279 0.2634 0.3964
Echinococcus granulosus hypothetical protein 0.0409 0.3906 0.5888
Onchocerca volvulus 0.001 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0232 0.2176 0.2164
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0687 0.6623 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0015 0.0057
Trypanosoma cruzi DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0279 0.2634 1
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0109 0.0981 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0193 0.0269
Brugia malayi Doublecortin family protein 0.001 0.002 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0193 0.0679
Schistosoma mansoni tensin-related 0.0409 0.3906 0.3897
Entamoeba histolytica hypothetical protein 0.0125 0.1134 0.1694
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0014 0.0058 0.0162
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0232 0.2176 0.3271
Onchocerca volvulus 0.0687 0.6623 0.6618
Brugia malayi hypothetical protein 0.001 0.002 0.0005
Brugia malayi Protein kinase domain containing protein 0.0687 0.6623 0.6618
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0409 0.3906 0.3897
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0041 0.0099
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.017 0.0156
Plasmodium vivax JmjC domain containing protein 0.0012 0.0034 0.0073
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Onchocerca volvulus 0.0279 0.2634 0.2623
Brugia malayi ImpB/MucB/SamB family protein 0.0011 0.0025 0.001
Brugia malayi hypothetical protein 0.0087 0.0764 0.075
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0279 0.2634 0.3964
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Entamoeba histolytica serine/threonine kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0279 0.2634 0.3964
Echinococcus granulosus glycine receptor subunit alpha 1 0.0232 0.2176 0.3271
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0232 0.2176 0.2164
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica tyrosin kinase, putative 0.0279 0.2634 0.3964
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0409 0.3906 0.3897
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0032 0.0232 0.083
Schistosoma mansoni microtubule-associated protein tau 0.0527 0.506 0.5053
Brugia malayi hypoxia-induced factor 1 0.008 0.0699 0.0685
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0232 0.2176 0.3271
Echinococcus multilocularis tyrosine protein kinase 0.0279 0.2634 0.3964
Plasmodium falciparum LCCL domain-containing protein 0.001 0.002 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Loa Loa (eye worm) GABA receptor subunit 0.0125 0.1134 0.1121
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0028 0.0193 0.0679
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Brugia malayi hypothetical protein 0.0409 0.3906 0.3897
Entamoeba histolytica ankyrin repeat protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0193 0.0679
Schistosoma mansoni ephrin receptor 0.0279 0.2634 0.2623
Echinococcus multilocularis 0.0409 0.3906 0.5888
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus granulosus N chimaerin 0.0409 0.3906 0.5888
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0687 0.6623 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0687 0.6623 1
Entamoeba histolytica tyrosin kinase, putative 0.0279 0.2634 0.3964
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0409 0.3906 0.5888
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Schistosoma mansoni SH2A 0.0409 0.3906 0.3897
Brugia malayi bHLH-PAS transcription factor 0.0019 0.0104 0.0089
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0014 0.0058 0.0162
Echinococcus multilocularis tensin 0.0409 0.3906 0.5888
Brugia malayi CXXC zinc finger family protein 0.0022 0.0131 0.0117
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Toxoplasma gondii histone lysine methyltransferase SET1 0.0042 0.0323 0.1226
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0232 0.2176 0.3271
Echinococcus granulosus tyrosine protein kinase Srms 0.0687 0.6623 1
Echinococcus granulosus single minded 2 0.0019 0.0104 0.0135
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Loa Loa (eye worm) STAT protein 0.0409 0.3906 0.3897
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Brugia malayi polk-prov protein 0.0024 0.0149 0.0134
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0107 0.0959 0.1429
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0125 0.1134 0.1121
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Giardia lamblia Kinase, NEK 0.0279 0.2634 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0031 0.0223 0.0796
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0279 0.2634 0.3964
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Loa Loa (eye worm) RGC/RGC protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis tyrosine protein kinase csk 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Echinococcus granulosus nAChR subunit 0.0125 0.1134 0.1694
Echinococcus granulosus tyrosine protein kinase Src42A 0.0687 0.6623 1
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0059 0.0494 0.1831
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0232 0.2176 0.2164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0687 0.6623 1
Schistosoma mansoni jumonji domain containing protein 0.0012 0.0034 0.0019
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Schistosoma mansoni tyrosine kinase 0.0687 0.6623 0.6618
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0029 0.0204 0.0286
Plasmodium falciparum protein kinase, putative 0.0279 0.2634 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0409 0.3906 0.3897
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Brugia malayi Tyrosine-protein kinase abl-1 0.0687 0.6623 0.6618
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.002 0.0007
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0279 0.2634 0.2623
Echinococcus multilocularis Polycystic kidney disease protein 0.001 0.002 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Entamoeba histolytica type A flavoprotein, putative 0.0023 0.0138 0.0186
Echinococcus granulosus SH2 motif 0.0409 0.3906 0.5888
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0687 0.6623 1
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0125 0.1134 0.1121
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0125 0.1134 0.1121
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Onchocerca volvulus 0.0687 0.6623 0.6618
Schistosoma mansoni phosphatidylserine receptor 0.0012 0.0034 0.0019
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.001 0.0015 0.0057
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0232 0.2176 0.3271
Loa Loa (eye worm) TK/ROR protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0232 0.2176 0.3271
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0232 0.2176 0.2164
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0409 0.3906 0.5888
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.2634 0.2623
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0279 0.2634 0.2623
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0687 0.6623 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.002 0.0007
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis transfer RNA-Thr 0.0279 0.2634 0.3964
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0047 0.0371 0.0357
Onchocerca volvulus 0.0338 0.3218 0.3208
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0687 0.6623 1
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Schistosoma mansoni aldehyde dehydrogenase 0.0032 0.0232 0.0218
Leishmania major p450 reductase, putative 0.0059 0.0494 0.1831
Loa Loa (eye worm) hypothetical protein 0.0338 0.3218 0.3208
Echinococcus granulosus lysine specific demethylase 6a 0.0012 0.0034 0.0029
Onchocerca volvulus 0.0687 0.6623 0.6618
Brugia malayi Sex muscle abnormal protein 5 0.0409 0.3906 0.3897
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0687 0.6623 1
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0687 0.6623 0.6618
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0687 0.6623 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0024 0.0149 0.0512
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis natriuretic peptide receptor 1 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Schistosoma mansoni aryl hydrocarbon receptor 0.0026 0.017 0.0155
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus dna polymerase eta 0.0011 0.0025 0.0015
Schistosoma mansoni lipoxygenase 0.0029 0.0204 0.0189
Onchocerca volvulus 0.0232 0.2176 0.2164
Brugia malayi C-terminal src kinase protein 1 0.0279 0.2634 0.2623
Schistosoma mansoni tyrosine kinase 0.0687 0.6623 0.6618
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0279 0.2634 1
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) TK/ABL protein kinase 0.0687 0.6623 0.6618
Toxoplasma gondii protein kinase domain-containing protein 0.0279 0.2634 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0016 0.0074 0.0615
Echinococcus granulosus JmjC domain containing protein 4 0.0012 0.0034 0.0029
Echinococcus granulosus SH2 domain containing protein 7 0.0409 0.3906 0.5888
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0409 0.3906 0.3897
Entamoeba histolytica type A flavoprotein, putative 0.0023 0.0138 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0279 0.2634 0.3964
Onchocerca volvulus 0.0687 0.6623 0.6618
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Brugia malayi hypothetical protein 0.0338 0.3218 0.3208
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0409 0.3906 0.5888
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Loa Loa (eye worm) flavodoxin family protein 0.0023 0.0138 0.0123
Brugia malayi cytokine inducible SH2-containing protein 5 0.0409 0.3906 0.3897
Entamoeba histolytica receptor protein kinase, putative 0.0279 0.2634 0.3964
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0014 0.0058 0.044
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Brugia malayi flavodoxin family protein 0.0023 0.0138 0.0123
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus activin receptor type 0.0279 0.2634 0.3964
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0107 0.0959 0.1429
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0193 0.0269
Plasmodium falciparum protein kinase, putative 0.0279 0.2634 1
Echinococcus granulosus epidermal growth factor receptor 0.0279 0.2634 0.3964
Onchocerca volvulus 0.0232 0.2176 0.2164
Echinococcus granulosus Polycystic kidney disease protein 0.001 0.002 0.0007
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Brugia malayi hypothetical protein 0.0279 0.2634 0.2623
Brugia malayi jmjC domain containing protein 0.0012 0.0034 0.0019
Echinococcus multilocularis dna polymerase kappa 0.0031 0.0223 0.0315
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica type A flavoprotein, putative 0.0023 0.0138 0.0186
Echinococcus multilocularis activin receptor type 0.0279 0.2634 0.3964
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0279 0.2634 0.2623
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0023 0.0138 0.047
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0012 0.0034 0.0019
Echinococcus granulosus tyrosine protein kinase shark 0.0687 0.6623 1
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0409 0.3906 0.5888
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0069 0.0594 0.058
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0028 0.0193 0.0269
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0012 0.0034 0.013
Schistosoma mansoni single-minded 0.0026 0.017 0.0155
Onchocerca volvulus 0.0409 0.3906 0.3897
Brugia malayi Tensin 0.0409 0.3906 0.3897
Loa Loa (eye worm) RGC/RGC protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Entamoeba histolytica type A flavoprotein, putative 0.0023 0.0138 0.0186
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0058 0.0162
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0193 0.0679
Loa Loa (eye worm) hypothetical protein 0.0338 0.3218 0.3208
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0012 0.0034 0.0073
Toxoplasma gondii oxidoreductase, putative 0.001 0.0015 0.0057
Echinococcus granulosus cpg binding protein 0.0023 0.0144 0.0195
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0028 0.0193 0.0178
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0015 0.0057
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0409 0.3906 0.5888
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0409 0.3906 0.3897
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Echinococcus granulosus glycine receptor subunit beta 0.0232 0.2176 0.3271
Loa Loa (eye worm) runx1 0.0042 0.0331 0.0317
Giardia lamblia DINP protein human, muc B family 0.0016 0.0074 0.0227
Schistosoma mansoni ap endonuclease 0.0014 0.0058 0.0043
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0028 0.0193 0.0679
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0079 0.0691 0.1024
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Brugia malayi hypothetical protein 0.0107 0.0959 0.0946
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0059 0.0494 0.1831
Onchocerca volvulus 0.0687 0.6623 0.6618
Loa Loa (eye worm) TK/ACK protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0687 0.6623 1
Loa Loa (eye worm) acetylcholine receptor protein 0.0107 0.0959 0.0946
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0107 0.0959 0.0946
Brugia malayi FAD binding domain containing protein 0.0059 0.0494 0.048
Onchocerca volvulus 0.0279 0.2634 0.2623
Echinococcus multilocularis SH2 motif 0.0409 0.3906 0.5888
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0041 0.0099
Onchocerca volvulus 0.0107 0.0959 0.0946
Echinococcus multilocularis lysine specific demethylase 6a 0.0012 0.0034 0.0029
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Giardia lamblia Protein 21.1 0.0279 0.2634 1
Echinococcus granulosus tensin 0.0409 0.3906 0.5888
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0012 0.0034 0.0073
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0014 0.0058 0.0162
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0279 0.2634 0.2623
Trypanosoma brucei DNA polymerase IV, putative 0.0031 0.0223 0.0796
Entamoeba histolytica cysteine surface protein, putative 0.0279 0.2634 0.3964
Schistosoma mansoni jumonji/arid domain-containing protein 0.0046 0.0368 0.0353
Onchocerca volvulus 0.0409 0.3906 0.3897
Schistosoma mansoni ephrin receptor 0.0279 0.2634 0.2623
Onchocerca volvulus 0.0687 0.6623 0.6618
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0232 0.2176 0.2164
Trichomonas vaginalis TK family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) FAD binding domain-containing protein 0.0059 0.0494 0.048
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0409 0.3906 0.5888
Toxoplasma gondii carbonyl reductase 1, putative 0.001 0.0015 0.0057
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Leishmania major protein kinase, putative 0.0279 0.2634 1
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0232 0.2176 0.3271
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Plasmodium falciparum tyrosine kinase-like protein 0.0279 0.2634 1
Toxoplasma gondii flavodoxin domain-containing protein 0.0029 0.0204 0.0773
Schistosoma mansoni tyrosine kinase 0.0687 0.6623 0.6618
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0232 0.2176 0.2164
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0107 0.0959 0.1429
Echinococcus multilocularis methionine synthase reductase 0.0037 0.0274 0.0392
Brugia malayi protein-tyrosine kinase 0.0687 0.6623 0.6618
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0015 0.0057
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) TK/DDR protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0687 0.6623 1
Echinococcus granulosus raf serine:threonine protein kinase 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Schistosoma mansoni ap endonuclease 0.0014 0.0058 0.0043
Echinococcus granulosus SH2 domain containing adapter protein F 0.0409 0.3906 0.5888
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0232 0.2176 0.3271
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0012 0.0034 0.013
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus tyrosine kinase 0.0687 0.6623 1
Schistosoma mansoni neurotransmitter gated ion channel 0.0125 0.1134 0.1121
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus ephrin type A receptor 4 A 0.0279 0.2634 0.3964
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Mycobacterium tuberculosis Conserved hypothetical protein 0.0011 0.0025 0.0106
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0279 0.2634 0.3964
Brugia malayi hypothetical protein 0.001 0.002 0.0005
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Echinococcus granulosus protein kinase 0.0279 0.2634 0.3964
Echinococcus multilocularis lysine specific demethylase 5A 0.0045 0.0356 0.0516
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Brugia malayi Tyrosine-protein kinase PR2 0.0279 0.2634 0.2623
Echinococcus multilocularis transfer RNA-Lys 0.0019 0.0104 0.0135
Toxoplasma gondii STE kinase 0.0279 0.2634 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0279 0.2634 0.2623
Schistosoma mansoni cpg binding protein 0.0023 0.0144 0.0129
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni phd/f-box containing protein 0.0012 0.0034 0.0019
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0409 0.3906 0.3897
Echinococcus granulosus ubiquitin specific protease 41 0.0028 0.0193 0.0269
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0059 0.0494 0.1831
Echinococcus multilocularis activated cdc42 kinase 1 0.0279 0.2634 0.3964
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Brugia malayi ImpB/MucB/SamB family protein 0.0011 0.0025 0.001
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Onchocerca volvulus 0.0409 0.3906 0.3897
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0125 0.1134 0.1121
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0232 0.2176 0.3271
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0005
Onchocerca volvulus 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Echinococcus granulosus epidermal growth factor receptor 0.0279 0.2634 0.3964
Plasmodium vivax tyrosine kinase-like protein, putative 0.0279 0.2634 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0028 0.0193 0.0679
Loa Loa (eye worm) TK/CSK protein kinase 0.0279 0.2634 0.2623
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus granulosus integrin linked protein kinase 0.0279 0.2634 0.3964
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus multilocularis dna polymerase eta 0.0011 0.0025 0.0015
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0023 0.0138 0.047
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0279 0.2634 0.3964
Schistosoma mansoni protein phosphatase 2C 0.0012 0.0034 0.0019
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis NCK adaptor protein 0.0409 0.3906 0.5888
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Schistosoma mansoni diflavin oxidoreductase 0.0029 0.0204 0.0189
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.001 0.0015 0.0057
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis tyrosine kinase 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0046 0.0048
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0232 0.2176 0.2164
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0014 0.0058 0.044
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Brugia malayi hypothetical protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Trichomonas vaginalis STE family protein kinase 0.0279 0.2634 1
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0279 0.2634 1
Echinococcus granulosus retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Brugia malayi jmjC domain containing protein 0.0012 0.0034 0.0019
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0023 0.0138 0.047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0107 0.0959 0.0946
Echinococcus multilocularis tyrosine protein kinase csk 0.0279 0.2634 0.3964
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0687 0.6623 0.6618
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0687 0.6623 1
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Echinococcus multilocularis jumonji domain containing 1A 0.0012 0.0034 0.0029
Schistosoma mansoni polycystin 1-related 0.001 0.002 0.0005
Echinococcus multilocularis phd:f box containing protein 0.0012 0.0034 0.0029
Entamoeba histolytica serine/threonine kinase, putative 0.0279 0.2634 0.3964
Brugia malayi ephrin receptor 1 precursor 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0232 0.2176 0.3271
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0279 0.2634 0.3964
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus lysine specific demethylase 5A 0.0046 0.0368 0.0534
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Schistosoma mansoni growth factor receptor-bound protein 0.0409 0.3906 0.3897
Schistosoma mansoni tyrosine kinase 0.0687 0.6623 0.6618
Mycobacterium ulcerans aldehyde dehydrogenase 0.0032 0.0232 0.225
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Echinococcus multilocularis glycine receptor subunit beta 0.0232 0.2176 0.3271
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Schistosoma mansoni hypothetical protein 0.0313 0.2966 0.2955
Schistosoma mansoni suppressor of cytokine signaling 0.0409 0.3906 0.3897
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0279 0.2634 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0028 0.0193 0.0269
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0107 0.0959 0.1429
Schistosoma mansoni loxhd1 0.001 0.002 0.0005
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0031 0.0223 0.0796
Schistosoma mansoni tensin 0.0409 0.3906 0.3897
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Brugia malayi Receptor family ligand binding region containing protein 0.0279 0.2634 0.2623
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0232 0.2176 0.2164
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Echinococcus multilocularis JmjC domain containing protein 4 0.0012 0.0034 0.0029
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0046 0.0048
Onchocerca volvulus Putative nachr subunit 0.0232 0.2176 0.2164
Echinococcus granulosus fibroblast growth factor receptor 4 0.0279 0.2634 0.3964
Echinococcus granulosus dna polymerase kappa 0.0031 0.0223 0.0315
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.001
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0279 0.2634 0.2623
Trypanosoma cruzi protein kinase, putative 0.0279 0.2634 1
Onchocerca volvulus 0.1034 1 1
Echinococcus granulosus suppressor of cytokine signaling 7 0.0409 0.3906 0.5888
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Echinococcus granulosus signal transduction protein lnk realted 0.0409 0.3906 0.5888
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0687 0.6623 1
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Schistosoma mansoni nck2/grb4 0.0409 0.3906 0.3897
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0232 0.2176 0.3271
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0409 0.3906 0.5888
Loa Loa (eye worm) serine/threonine protein kinase 0.0279 0.2634 0.2623
Toxoplasma gondii aldehyde dehydrogenase 0.0032 0.0232 0.0882
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0279 0.2634 0.2623
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) FAD binding domain-containing protein 0.0037 0.0274 0.0259
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0232 0.2176 0.3271
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trypanosoma cruzi p450 reductase, putative 0.0059 0.0494 0.1831
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0029 0.0204 0.0286
Brugia malayi Cation transporter family protein 0.0232 0.2176 0.2164
Echinococcus granulosus tyrosine protein kinase csk 0.0279 0.2634 0.3964
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Brugia malayi Raf kinase 0.0279 0.2634 0.2623
Echinococcus granulosus glycine receptor subunit beta 0.0232 0.2176 0.3271
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0109 0.0981 1
Schistosoma mansoni cpg binding protein 0.0023 0.0144 0.0129
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Onchocerca volvulus 0.0019 0.0104 0.0089
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus granulosus activated cdc42 kinase 1 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Onchocerca volvulus 0.1034 1 1
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0279 0.2634 0.3964
Schistosoma mansoni tyrosine protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0409 0.3906 0.5888
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0409 0.3906 0.3897
Brugia malayi hypothetical protein 0.0107 0.0959 0.0946
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0279 0.2634 0.3964
Leishmania major hypothetical protein, conserved 0.0012 0.0034 0.0073
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Plasmodium falciparum protein kinase, putative 0.0279 0.2634 1
Brugia malayi Cytochrome P450 family protein 0.0026 0.017 0.0156
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0109 0.0981 1
Echinococcus granulosus tyrosine kinase 0.0687 0.6623 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0409 0.3906 0.5888
Loa Loa (eye worm) ACC-1 protein 0.0232 0.2176 0.2164
Echinococcus multilocularis tyrosine protein kinase csk 0.0279 0.2634 0.3964
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Echinococcus granulosus lipoxygenase domain containing protein 0.001 0.002 0.0007
Schistosoma mansoni lozenge 0.0042 0.0331 0.0317
Brugia malayi Furin-like cysteine rich region family protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0279 0.2634 1
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0279 0.2634 0.2623
Onchocerca volvulus Tyrosine kinase homolog 0.0279 0.2634 0.2623
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0023 0.0138 0.047
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0023 0.0138 0.047
Echinococcus granulosus activated cdc42 kinase 1 0.0279 0.2634 0.3964
Loa Loa (eye worm) jmjC domain-containing protein 0.0012 0.0034 0.0019
Echinococcus granulosus phd:f box containing protein 0.0012 0.0034 0.0029
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0032 0.0232 0.225
Loa Loa (eye worm) TK/ALK protein kinase 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.1034 1 1
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0279 0.2634 0.2623
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0014 0.0058 0.0162
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Onchocerca volvulus 0.0279 0.2634 0.2623
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Onchocerca volvulus 0.001 0.002 0.0005
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0059 0.0494 0.0726
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0409 0.3906 0.5888
Echinococcus multilocularis FL cytokine receptor 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0279 0.2634 0.3964
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0079 0.0691 0.1024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0034 0.0019
Brugia malayi Protein kinase domain containing protein 0.0687 0.6623 0.6618
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) TK/FER protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis protein KINase family member (kin 25) 0.0279 0.2634 0.3964
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0409 0.3906 0.3897
Leishmania major hypothetical protein, conserved 0.0023 0.0138 0.047
Schistosoma mansoni acetylcholine receptor-related 0.0107 0.0959 0.0946
Loa Loa (eye worm) jmjC domain-containing protein 0.0012 0.0034 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus granulosus insulin receptor 0.0279 0.2634 0.3964
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Schistosoma mansoni neurotransmitter gated ion channel 0.0107 0.0959 0.0946
Giardia lamblia Kinase, NEK 0.0279 0.2634 1
Echinococcus multilocularis signal transduction protein lnk realted 0.0409 0.3906 0.5888
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0232 0.2176 0.3271
Echinococcus multilocularis kinase suppressor of Ras 1 0.0279 0.2634 0.3964
Plasmodium vivax protein kinase, putative 0.0279 0.2634 1
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0023 0.0138 0.047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0107 0.0959 0.0946
Schistosoma mansoni hypothetical protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Trypanosoma brucei unspecified product 0.0026 0.0174 0.0608
Schistosoma mansoni NADPH flavin oxidoreductase 0.003 0.0208 0.0193
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein kinase, putative 0.0409 0.3906 0.5888
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus granulosus tyrosine protein kinase pr2 0.0279 0.2634 0.3964
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0279 0.2634 0.3964
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0014 0.0058 0.0064
Onchocerca volvulus 0.0022 0.0131 0.0117
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0687 0.6623 0.6618
Loa Loa (eye worm) CXXC zinc finger family protein 0.0022 0.0131 0.0117
Schistosoma mansoni tyrosine kinase 0.0687 0.6623 0.6618
Loa Loa (eye worm) doublecortin family protein 0.001 0.002 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Echinococcus multilocularis SH2 motif 0.0409 0.3906 0.5888
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0041 0.0099
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0011 0.0025 0.001
Trypanosoma brucei DNA polymerase eta, putative 0.0011 0.0025 0.0039
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0079 0.0691 0.0677
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0232 0.2176 0.3271
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0012 0.0034 0.0073
Echinococcus multilocularis heat shock protein 70 0.0279 0.2634 0.3964
Echinococcus multilocularis tyrosine protein kinase pr2 0.0279 0.2634 0.3964
Loa Loa (eye worm) hypothetical protein 0.1034 1 1
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0232 0.2176 0.3271
Echinococcus granulosus tyrosine protein kinase 0.0279 0.2634 0.3964
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0279 0.2634 1
Entamoeba histolytica serine/threonine kinase, putative 0.0279 0.2634 0.3964
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0279 0.2634 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0279 0.2634 0.3964
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0279 0.2634 0.2623
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0125 0.1134 0.1121
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0014 0.0058 0.0064
Echinococcus multilocularis protein tyrosine kinase 0.0279 0.2634 0.3964
Plasmodium falciparum JmjC domain-containing protein, putative 0.0012 0.0034 0.0073
Brugia malayi jmjC domain containing protein 0.0046 0.0368 0.0353
Schistosoma mansoni jumonji domain containing protein 0.0045 0.0356 0.0341
Trypanosoma cruzi DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Trichomonas vaginalis sulfite reductase, putative 0.0059 0.0494 0.1831
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Brugia malayi jmjC domain containing protein 0.0045 0.0356 0.0341
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0687 0.6623 1
Trichomonas vaginalis ap endonuclease, putative 0.0014 0.0058 0.0162
Entamoeba histolytica tyrosine kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis Protein lozenge 0.0042 0.0331 0.0479
Schistosoma mansoni signal transduction protein lnk-related 0.0409 0.3906 0.3897
Onchocerca volvulus 0.0409 0.3906 0.3897
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0059 0.0494 0.0726
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0232 0.2176 0.2164
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0107 0.0959 0.1429
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0023 0.0138 0.047
Plasmodium vivax multidomain scavenger receptor, putative 0.001 0.002 0.0018
Onchocerca volvulus 0.0409 0.3906 0.3897
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0059 0.0494 0.1831
Schistosoma mansoni shc transforming protein 0.0409 0.3906 0.3897
Echinococcus granulosus retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0014 0.0058 0.0162
Echinococcus granulosus kinase suppressor of Ras 1 0.0279 0.2634 0.3964
Entamoeba histolytica serine/threonine kinase, putative 0.0279 0.2634 0.3964
Trichomonas vaginalis conserved hypothetical protein 0.0279 0.2634 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0014 0.0058 0.0162
Trypanosoma brucei Flagellum attachment zone protein 20 0.0279 0.2634 1
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.001 0.0015 0.0057
Schistosoma mansoni hypothetical protein 0.0409 0.3906 0.3897
Echinococcus multilocularis growth factor receptor bound protein 2 0.0409 0.3906 0.5888
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0232 0.2176 0.2164
Entamoeba histolytica type A flavoprotein, putative 0.0023 0.0138 0.0186
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Chlamydia trachomatis sulfite reductase 0.0037 0.0274 0.5
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0059 0.0494 0.1831
Loa Loa (eye worm) SRC-1 0.0687 0.6623 0.6618
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0232 0.2176 0.2164
Echinococcus multilocularis lipoxygenase domain containing protein 0.001 0.002 0.0007
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0023 0.0138 0.047
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Onchocerca volvulus 0.0409 0.3906 0.3897
Onchocerca volvulus 0.0279 0.2634 0.2623
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0059 0.0494 0.1831
Echinococcus granulosus RUN 0.001 0.002 0.0007
Schistosoma mansoni tyrosine kinase 0.0687 0.6623 0.6618
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis epidermal growth factor receptor 0.0279 0.2634 0.3964
Echinococcus granulosus tyrosine protein kinase ABL1 0.0687 0.6623 1
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Schistosoma mansoni suppressor of cytokine signaling 0.0409 0.3906 0.3897
Echinococcus multilocularis SHC transforming protein 3 0.0409 0.3906 0.5888
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0232 0.2176 0.2164
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Schistosoma mansoni lipoxygenase 0.001 0.002 0.0005
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Onchocerca volvulus 0.1034 1 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Schistosoma mansoni protein kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis raf serine:threonine protein kinase 0.0279 0.2634 0.3964
Echinococcus multilocularis microtubule associated protein 2 0.0527 0.506 0.7636
Onchocerca volvulus 0.0279 0.2634 0.2623
Echinococcus multilocularis SH2 motif 0.0409 0.3906 0.5888
Echinococcus multilocularis c src tyrosine kinase 0.0687 0.6623 1
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Echinococcus multilocularis glycine receptor subunit beta 0.0232 0.2176 0.3271
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Schistosoma mansoni terminal deoxycytidyl transferase 0.0011 0.0025 0.001
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Echinococcus granulosus microtubule associated protein 2 0.0527 0.506 0.7636
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0045 0.0356 0.0516
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0125 0.1134 0.1121
Schistosoma mansoni aldehyde dehydrogenase 0.0032 0.0232 0.0218
Echinococcus multilocularis tyrosine protein kinase csk 0.0279 0.2634 0.3964
Echinococcus granulosus dnaJ subfamily B 0.0313 0.2966 0.4466
Brugia malayi Variant SH3 domain containing protein 0.0409 0.3906 0.3897
Brugia malayi hypothetical protein 0.0687 0.6623 0.6618
Echinococcus multilocularis nAChR subunit 0.0125 0.1134 0.1694
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0011 0.0025 0.0015
Loa Loa (eye worm) TK protein kinase 0.0687 0.6623 0.6618
Echinococcus multilocularis tyrosine protein kinase Blk 0.0687 0.6623 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.0959 0.0946
Loa Loa (eye worm) jmjC domain-containing protein 0.0012 0.0034 0.0019
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Schistosoma mansoni nAChR subunit 0.0232 0.2176 0.2164
Entamoeba histolytica ankyrin repeat protein 0.0279 0.2634 0.3964
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0079 0.0691 0.6999
Echinococcus granulosus glycine receptor subunit alpha 1 0.0232 0.2176 0.3271
Onchocerca volvulus 0.0232 0.2176 0.2164
Onchocerca volvulus 0.0279 0.2634 0.2623
Brugia malayi exodeoxyribonuclease III family protein 0.0014 0.0058 0.0043
Leishmania major hypothetical protein, conserved 0.0279 0.2634 1
Brugia malayi SRC-1 0.0687 0.6623 0.6618
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0232 0.2176 0.3271
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Schistosoma mansoni GTPase activating protein 0.0409 0.3906 0.3897
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0125 0.1134 0.1121
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Onchocerca volvulus 0.0107 0.0959 0.0946
Brugia malayi jmjC domain containing protein 0.0012 0.0034 0.0019
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Brugia malayi Variant SH3 domain containing protein 0.0409 0.3906 0.3897
Schistosoma mansoni rab6-interacting 0.001 0.002 0.0005
Brugia malayi Guanylyl cyclase protein 23 0.0279 0.2634 0.2623
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis protein tyrosine kinase, putative 0.0279 0.2634 1
Loa Loa (eye worm) ACC-1 protein 0.0232 0.2176 0.2164
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Echinococcus granulosus suppressor of cytokine signaling 6 0.0409 0.3906 0.5888
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0011 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Brugia malayi Protein kinase domain containing protein 0.0687 0.6623 0.6618
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus granulosus tyrosine kinase 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypoxia-induced factor 1 0.008 0.0699 0.0685
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0079 0.0691 0.2583
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0059 0.0494 0.1831
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.001 0.0015 0.0057
Brugia malayi SH2 domain containing protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) LGC-31 protein 0.0232 0.2176 0.2164
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0687 0.6623 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0031 0.0223 0.0796
Brugia malayi SH2 domain containing protein 0.0687 0.6623 0.6618
Trypanosoma cruzi protein kinase, putative 0.0279 0.2634 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0223 0.2096 0.3149
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0232 0.2176 0.2164
Echinococcus granulosus tyrosine protein kinase Src42A 0.0409 0.3906 0.5888
Echinococcus granulosus methionine synthase reductase 0.0037 0.0274 0.0392
Entamoeba histolytica receptor protein kinase, putative 0.0279 0.2634 0.3964
Loa Loa (eye worm) TK protein kinase 0.0279 0.2634 0.2623
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Echinococcus multilocularis dnaJ subfamily B 0.0313 0.2966 0.4466
Brugia malayi tRNA modification GTPase TrmE family protein 0.0409 0.3906 0.3897
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0028 0.0193 0.0178
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Schistosoma mansoni tyrosine kinase 0.0279 0.2634 0.2623
Schistosoma mansoni vav2 0.0409 0.3906 0.3897
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0279 0.2634 0.3964
Brugia malayi Protein kinase domain containing protein 0.0279 0.2634 0.2623
Echinococcus multilocularis tyrosine protein kinase shark 0.0687 0.6623 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0011 0.0025 0.0015
Loa Loa (eye worm) hypothetical protein 0.0232 0.2176 0.2164
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0023 0.0138 0.047
Echinococcus granulosus tyrosine protein kinase Fyn 0.0687 0.6623 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0232 0.2176 0.2164
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0687 0.6623 1
Plasmodium vivax hypothetical protein, conserved 0.0023 0.0138 0.047
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0232 0.2176 0.2164
Mycobacterium ulcerans DNA polymerase IV 0.0031 0.0223 0.2156
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0409 0.3906 0.3897
Echinococcus multilocularis ubiquitin specific protease 41 0.0028 0.0193 0.0269
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0232 0.2176 0.2164
Echinococcus granulosus retinal guanylyl cyclase 2 0.0279 0.2634 0.3964
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0107 0.0959 0.0946
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.2634 0.3964
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0016 0.0074 0.0227
Loa Loa (eye worm) TK/RYK protein kinase 0.0279 0.2634 0.2623
Leishmania major cytochrome P450 reductase, putative 0.0052 0.0429 0.158
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0014 0.0058 0.0043
Echinococcus granulosus c src tyrosine kinase 0.0687 0.6623 1
Schistosoma mansoni tensin 0.0409 0.3906 0.3897
Entamoeba histolytica protein kinase, putative 0.0279 0.2634 0.3964
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0687 0.6623 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0232 0.2176 0.2164
Loa Loa (eye worm) TK/FER protein kinase 0.0687 0.6623 0.6618
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0052 0.0429 0.158
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0107 0.0959 0.0946
Echinococcus multilocularis protein kinase 0.0279 0.2634 0.3964
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0279 0.2634 0.2623
Loa Loa (eye worm) hypothetical protein 0.0279 0.2634 0.2623
Entamoeba histolytica tyrosin kinase, putative 0.0279 0.2634 0.3964
Toxoplasma gondii protein kinase 0.0279 0.2634 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0223 0.2096 0.7944
Loa Loa (eye worm) hypothetical protein 0.0409 0.3906 0.3897
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0232 0.2176 0.2164
Echinococcus granulosus SHC transforming protein 3 0.0409 0.3906 0.5888
Plasmodium vivax tyrosine kinase-like protein, putative 0.0279 0.2634 1
Leishmania major DNA polymerase kappa, putative 0.0016 0.0074 0.0227
Loa Loa (eye worm) RGC/RGC protein kinase 0.0279 0.2634 0.2623
Schistosoma mansoni neurotransmitter gated ion channel 0.0107 0.0959 0.0946
Echinococcus multilocularis RUN 0.001 0.002 0.0007
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0279 0.2634 0.3964
Brugia malayi FAD binding domain containing protein 0.0037 0.0274 0.0259
Onchocerca volvulus 0.0125 0.1134 0.1121
Schistosoma mansoni rab6-interacting 0.001 0.002 0.0005
Schistosoma mansoni hypothetical protein 0.001 0.002 0.0005
Echinococcus granulosus NCK adaptor protein 0.0409 0.3906 0.5888
Echinococcus multilocularis SH2 domain containing protein 7 0.0409 0.3906 0.5888
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0032 0.0232 0.0329
Trypanosoma cruzi DNA polymerase eta, putative 0.0011 0.0025 0.0039
Entamoeba histolytica hypothetical protein 0.0279 0.2634 0.3964
Loa Loa (eye worm) jmjC domain-containing protein 0.0046 0.0368 0.0353
Toxoplasma gondii oxidoreductase, putative 0.001 0.0015 0.0057
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0279 0.2634 0.3964
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1
Trichomonas vaginalis TKL family protein kinase 0.0279 0.2634 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.8 uM Inhibitory concentration of the compound was tested against Inducible nitric oxide synthase (iNOS) ChEMBL. 12392746
IC50 (binding) = 2.8 uM Inhibitory concentration of the compound was tested against Inducible nitric oxide synthase (iNOS) ChEMBL. 12392746
IC50 (binding) = 49 uM Inhibitory concentration of the compound was tested against Neuronal nitric oxide synthase ChEMBL. 12392746
IC50 (binding) = 49 uM Inhibitory concentration of the compound was tested against Neuronal nitric oxide synthase ChEMBL. 12392746
IC50 (binding) = 2930 uM Inhibitory concentration of the compound was tested against Endothelial nitric oxide synthase ChEMBL. 12392746
IC50 (binding) = 2930 uM Inhibitory concentration of the compound was tested against Endothelial nitric oxide synthase ChEMBL. 12392746
Selectivity (binding) = 18 Selectivity was determined by the ratio of IC50 (nNOS) to the IC50 (iNOS) ChEMBL. 12392746
Selectivity (binding) = 1046 Selectivity was determined by the ratio of IC50 (eNOS) to the IC50 (iNOS) ChEMBL. 12392746

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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