Detailed information for compound 2071698

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.468 | Formula: C16H25N5OS
  • H donors: 0 H acceptors: 3 LogP: 2.21 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CCc1scc(n1)CN1CCOC(C1)Cn1cncn1)C
  • InChi: 1S/C16H25N5OS/c1-13(2)3-4-16-19-14(10-23-16)7-20-5-6-22-15(8-20)9-21-12-17-11-18-21/h10-13,15H,3-9H2,1-2H3
  • InChiKey: VEYJHEWZMFJPAT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glutaminase, putative 0.0119 0.1173 1
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Toxoplasma gondii methionyl-tRNA synthetase 0.0032 0.0255 0.726
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0117 0.2388
Trypanosoma cruzi MFS transporter, putative 0.0031 0.0248 0.6908
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0145 0.4124
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0032 0.0255 0.7135
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0117 0.0074
Entamoeba histolytica UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.004 0.0347 0.9796
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0353 0.3515
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0353 0.301
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0032 0.0255 0.7135
Schistosoma mansoni endoplasmin 0.0014 0.0073 0.0621
Brugia malayi SPARC precursor 0.0021 0.0145 0.1237
Trypanosoma cruzi tyrosyl-tRNA synthetase, putative 0.0041 0.0352 0.996
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0117 0.3071
Loa Loa (eye worm) hypothetical protein 0.0021 0.0145 0.1237
Echinococcus granulosus follistatin 0.0021 0.0145 0.1444
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0353 0.301
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0117 0.1162
Echinococcus granulosus heat shock protein 90 0.0014 0.0073 0.0725
Echinococcus multilocularis heat shock protein 90 0.0011 0.0043 0.0424
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0353 0.3515
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.004 0.0347 0.9832
Schistosoma mansoni glutaminase 0.0119 0.1173 1
Schistosoma mansoni heat shock protein 0.0014 0.0073 0.0621
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0013 0.0061 0.0517
Toxoplasma gondii heat shock protein HSP90 0.0014 0.0073 0.2069
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0031 0.0248 0.2465
Echinococcus granulosus lamin dm0 0.0012 0.0047 0.0473
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0405
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Brugia malayi Intermediate filament tail domain containing protein 0.0012 0.0047 0.0405
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0145 0.1237
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0255 0.7135
Giardia lamblia Methionyl-tRNA synthetase 0.0032 0.0255 0.6852
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0248 0.704
Trypanosoma cruzi heat shock protein 90, putative 0.0014 0.0073 0.1783
Brugia malayi Endoplasmin precursor 0.0014 0.0073 0.0621
Loa Loa (eye worm) hypothetical protein 0.0008 0.0008 0.0072
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0145 0.1237
Echinococcus multilocularis lamin 0.0012 0.0047 0.0473
Schistosoma mansoni tar DNA-binding protein 0.0028 0.0214 0.1822
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Toxoplasma gondii tRNA synthetases class I family protein 0.0041 0.0352 1
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, beta chain PheT 0.0032 0.0255 0.0214
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0013 0.0056 0.0554
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0248 0.2461
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0248 0.2111
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0255 0.2073
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0353 0.3515
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0353 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0117 0.1567
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0117 0.3071
Loa Loa (eye worm) hypothetical protein 0.0041 0.0353 0.301
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0117 0.3319
Echinococcus multilocularis UDP N acetylglucosamine dolichyl phosphate 0.004 0.0347 0.3458
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit beta 0.0032 0.0255 0.0214
Onchocerca volvulus 0.0031 0.0248 0.2461
Echinococcus granulosus lamin 0.0012 0.0047 0.0473
Onchocerca volvulus 0.0012 0.0047 0.0472
Giardia lamblia Tyrosyl-tRNA synthetase 0.0041 0.0352 0.9956
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0353 0.2917
Schistosoma mansoni tar DNA-binding protein 0.0028 0.0214 0.1822
Loa Loa (eye worm) hypothetical protein 0.0009 0.0018 0.015
Schistosoma mansoni tar DNA-binding protein 0.0028 0.0214 0.1822
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0041 0.0352 0.9951
Plasmodium falciparum heat shock protein 90 0.0014 0.0073 0.2069
Echinococcus granulosus aminoacyl tRNA synthase complex interacting 0.0032 0.0255 0.2542
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0011 0.0043 0.0424
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.004 0.0347 0.2962
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 0.0366 0.3754 1
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0145 0.4124
Onchocerca volvulus 0.0031 0.0248 0.2461
Loa Loa (eye worm) RNA binding protein 0.0028 0.0214 0.1822
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0255 0.2073
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0145 0.1237
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0117 0.0875
Trichomonas vaginalis heat shock protein, putative 0.0011 0.0043 0.0235
Echinococcus granulosus UDP N acetylglucosamine dolichyl phosphate 0.004 0.0347 0.3458
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0353 0.301
Loa Loa (eye worm) hypothetical protein 0.0013 0.0061 0.0517
Echinococcus multilocularis heat shock protein 90 0.0014 0.0073 0.0725
Loa Loa (eye worm) agrin synaptic family protein 0.0021 0.0145 0.1237
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0021 0.0145 0.1237
Schistosoma mansoni heat shock protein 0.0014 0.0073 0.0621
Onchocerca volvulus 0.0021 0.0145 0.1441
Loa Loa (eye worm) intermediate filament protein 0.0012 0.0047 0.0405
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0964 1 1
Echinococcus multilocularis endoplasmin 0.0011 0.0043 0.0424
Brugia malayi glutaminase DH11.1 0.0119 0.1173 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0061 0.0517
Plasmodium vivax N-acetylglucosamine-1-phosphate transferase, putative 0.004 0.0347 0.9877
Schistosoma mansoni organic anion transporter 0.0031 0.0248 0.2111
Onchocerca volvulus 0.0103 0.1006 1
Onchocerca volvulus 0.0031 0.0248 0.2461
Brugia malayi hypothetical protein 0.0031 0.0248 0.2111
Trypanosoma brucei UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.004 0.0347 0.9796
Entamoeba histolytica tyrosyl-tRNA synthetase, putative 0.0041 0.0352 0.9951
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0964 1 1
Plasmodium vivax endoplasmin, putative 0.0014 0.0073 0.2069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0061 0.0517
Trichomonas vaginalis heat shock protein, putative 0.0011 0.0043 0.0235
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0031 0.0248 0.2465
Brugia malayi GCC2 and GCC3 family protein 0.0009 0.0018 0.015
Leishmania major UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.004 0.0347 0.9816
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0013 0.0061 0.1725
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0248 0.2461
Schistosoma mansoni UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.004 0.0347 0.2962
Schistosoma mansoni lamin 0.0012 0.0047 0.0405
Echinococcus multilocularis follistatin 0.0021 0.0145 0.1444
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0353 0.3515
Schistosoma mansoni agrin 0.0021 0.0145 0.1237
Onchocerca volvulus 0.004 0.0347 0.3452
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Giardia lamblia Heat shock protein HSP 90-alpha 0.0014 0.0073 0.0974
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0028 0.0214 0.1822
Trypanosoma cruzi heat shock protein 85, putative 0.0014 0.0073 0.1783
Echinococcus granulosus heat shock protein 90 0.0011 0.0043 0.0424
Toxoplasma gondii exonuclease III APE 0.0018 0.0117 0.3319
Echinococcus multilocularis tyrosyl tRNA synthetase 0.0073 0.0683 0.6797
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit beta 0.0032 0.0255 0.0214
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0117 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0255 0.2073
Schistosoma mansoni tyrosyl-tRNA synthetase 0.0073 0.0683 0.5821
Brugia malayi intermediate filament protein 0.0012 0.0047 0.0405
Echinococcus granulosus agrin 0.0021 0.0145 0.1444
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Loa Loa (eye worm) heat shock protein 90 0.0014 0.0073 0.0621
Plasmodium falciparum endoplasmin, putative 0.0009 0.0015 0.0438
Echinococcus granulosus survival motor neuron protein 1 0.0103 0.1004 1
Onchocerca volvulus 0.0031 0.0248 0.2461
Onchocerca volvulus Putative organic anion transporter 0.0031 0.0248 0.2461
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0021 0.0145 0.1233
Schistosoma mansoni ap endonuclease 0.0018 0.0117 0.0995
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0012 0.0047 0.0405
Loa Loa (eye worm) glutaminase 2 0.0119 0.1173 1
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0255 0.2073
Schistosoma mansoni intermediate filament proteins 0.0012 0.0047 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0045 0.0386
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0117 0.02
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0091 0.0875 0.7459
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0353 1
Echinococcus granulosus tar DNA binding protein 0.0028 0.0214 0.2127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0353 0.2917
Leishmania major tyrosyl or methionyl-tRNA synthetase-like protein 0.0032 0.0255 0.6852
Echinococcus multilocularis survival motor neuron protein 1 0.0103 0.1004 1
Loa Loa (eye worm) TAR-binding protein 0.0028 0.0214 0.1822
Toxoplasma gondii protease inhibitor PI2 0.0021 0.0145 0.4124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0353 0.2917
Plasmodium falciparum tyrosine--tRNA ligase 0.0041 0.0352 1
Schistosoma mansoni survival motor neuron protein 0.0021 0.0145 0.1233
Brugia malayi Pre-SET motif family protein 0.0091 0.0875 0.7459
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0013 0.0061 0.0604
Entamoeba histolytica hypothetical protein 0.0032 0.0255 0.6513
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0117 0.0074
Trypanosoma brucei tyrosyl/methionyl-tRNA synthetase, putative 0.0032 0.0255 0.6513
Echinococcus granulosus endoplasmin 0.0011 0.0043 0.0424
Loa Loa (eye worm) hypothetical protein 0.0021 0.0145 0.1237
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0964 1 1
Brugia malayi TAR-binding protein 0.0028 0.0214 0.1822
Schistosoma mansoni lamin 0.0012 0.0047 0.0405
Echinococcus multilocularis expressed protein 0.0021 0.0145 0.1444
Brugia malayi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.004 0.0347 0.2962
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0117 0.0995
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0353 1
Schistosoma mansoni follistatin 0.0021 0.0145 0.1237
Echinococcus granulosus histone lysine methyltransferase setb 0.0013 0.0061 0.0604
Echinococcus multilocularis tar DNA binding protein 0.0028 0.0214 0.2127
Loa Loa (eye worm) hypothetical protein 0.0103 0.1004 0.8563
Loa Loa (eye worm) hypothetical protein 0.004 0.0347 0.2962
Onchocerca volvulus 0.0013 0.0061 0.0603
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0255 0.7135
Plasmodium vivax heat shock protein 86, putative 0.0014 0.0073 0.2069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0145 0.1237
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Onchocerca volvulus 0.0031 0.0248 0.2461
Toxoplasma gondii heat shock protein 90, putative 0.0014 0.0073 0.2069
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0145 0.4124
Loa Loa (eye worm) glutaminase 0.0119 0.1173 1
Schistosoma mansoni ap endonuclease 0.0018 0.0117 0.0995
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Entamoeba histolytica hypothetical protein 0.0032 0.0255 0.6513
Mycobacterium ulcerans undecapaprenyl-phosphate alpha-N-acetylglucosaminyltransferase Rfe 0.004 0.0347 0.0306
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0117 0.0875
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0145 0.4124
Echinococcus granulosus Solute carrier organic anion transporter family 0.0031 0.0248 0.2465
Brugia malayi secreted modular calcium-binding protein 1 0.0021 0.0145 0.1237
Onchocerca volvulus 0.0021 0.0145 0.1437
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0021 0.0145 0.1237
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0117 0.2388
Trypanosoma cruzi heat shock protein 85, putative 0.0014 0.0073 0.1783
Trichomonas vaginalis set domain proteins, putative 0.0103 0.1006 0.856
Schistosoma mansoni tar DNA-binding protein 0.0028 0.0214 0.1822
Trichomonas vaginalis glucosaminephosphotransferase, putative 0.004 0.0347 0.2868
Schistosoma mansoni tar DNA-binding protein 0.0028 0.0214 0.1822
Mycobacterium ulcerans glutaminase 0.0119 0.1173 0.1135
Echinococcus granulosus heat shock protein 0.0014 0.0073 0.0725
Echinococcus multilocularis agrin 0.0021 0.0145 0.1444
Echinococcus granulosus tyrosyl tRNA synthetase 0.0073 0.0683 0.6797
Brugia malayi methionyl-tRNA synthetase 0.0032 0.0255 0.2177
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0353 1
Brugia malayi hypothetical protein 0.0031 0.0248 0.2111
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0353 0.3515
Plasmodium vivax methionine-tRNA ligase, putative 0.0032 0.0255 0.726
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Trypanosoma cruzi heat shock protein 85, putative 0.0014 0.0073 0.1783
Leishmania major hypothetical protein, conserved 0.0032 0.0255 0.6852
Echinococcus multilocularis aminoacyl tRNA synthase complex interacting 0.0032 0.0255 0.2542
Schistosoma mansoni organic anion transporter 0.0031 0.0248 0.2111
Echinococcus granulosus intermediate filament protein 0.0012 0.0047 0.0473
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Toxoplasma gondii rhoptry neck protein RON9 0.0007 0.0000000057103 0.00000016238
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0041 0.0352 0.2906
Trypanosoma cruzi UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.004 0.0347 0.9832
Brugia malayi RNA recognition motif domain containing protein 0.0028 0.0214 0.1822
Schistosoma mansoni methionyl-tRNA synthetase 0.0032 0.0255 0.2177
Trichomonas vaginalis methionyl-tRNA synthetase, putative 0.0032 0.0255 0.2073
Echinococcus multilocularis lamin dm0 0.0012 0.0047 0.0473
Toxoplasma gondii glycosyl transferase, group 4 family protein 0.004 0.0347 0.9877
Plasmodium falciparum UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, putative 0.004 0.0347 0.9877
Schistosoma mansoni endoplasmin 0.0014 0.0073 0.0621
Toxoplasma gondii tRNA binding domain-containing protein 0.0032 0.0255 0.726
Trichomonas vaginalis heat shock protein, putative 0.0011 0.0043 0.0235
Schistosoma mansoni hypothetical protein 0.0021 0.0145 0.1233
Brugia malayi prostaglandin transporter 0.0031 0.0248 0.2111
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0073 0.0496
Trypanosoma cruzi heat shock protein 85, putative 0.0011 0.0043 0.0897
Brugia malayi Pre-SET motif family protein 0.0013 0.0061 0.0517
Echinococcus multilocularis musashi 0.0012 0.0047 0.0473
Leishmania major hypothetical protein 0.0032 0.0255 0.6852
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0117 0.0995
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0032 0.0255 0.2177
Giardia lamblia UDP-N-acetylglucosamine-dolichyl-phosphateN-acetylglucosaminephosphotransferase 0.004 0.0347 0.9816
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0117 0.1162
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0032 0.0255 0.6513
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0013 0.0061 0.0604
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0366 0.3754 1
Brugia malayi hypothetical protein 0.0103 0.1004 0.8563
Echinococcus multilocularis heat shock protein 0.0014 0.0073 0.0725
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0013 0.0061 0.0517
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0353 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0353 0.3515
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0031 0.0248 0.2111
Treponema pallidum methionyl-tRNA synthetase 0.0032 0.0255 0.0573
Plasmodium vivax SET domain protein, putative 0.0013 0.0061 0.1725
Leishmania major heat shock protein 83-1 0.0014 0.0073 0.0974
Trypanosoma cruzi heat shock protein 90, putative 0.0011 0.0043 0.0897
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Onchocerca volvulus 0.0012 0.0047 0.0472
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0031 0.0248 0.2465
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0117 0.1567
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0248 0.2111
Loa Loa (eye worm) hypothetical protein 0.0021 0.0145 0.1237
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0032 0.0255 0.6513
Plasmodium vivax tyrosine--tRNA ligase, putative 0.0041 0.0352 1
Plasmodium falciparum tRNA import protein tRIP 0.0032 0.0255 0.726
Loa Loa (eye worm) endoplasmin 0.0014 0.0073 0.0621
Brugia malayi sodium-independent organic anion transporter family protein 0.0031 0.0248 0.2111
Loa Loa (eye worm) hypothetical protein 0.0031 0.0248 0.2111
Brugia malayi heat shock protein 90 0.0014 0.0073 0.0621
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0353 1
Trypanosoma cruzi Heat shock protein 83, putative 0.0014 0.0073 0.1783
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0117 0.3319
Leishmania major tyrosyl-tRNA synthetase, putative 0.0041 0.0352 0.9956
Brugia malayi RNA binding protein 0.0028 0.0214 0.1822

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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