Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | GPCR, family 2 | 0.0076 | 0.1318 | 0.1291 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.019 | 0.3537 | 0.7832 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0076 | 0.1318 | 0.2874 |
Brugia malayi | Bromodomain containing protein | 0.0018 | 0.0192 | 0.0358 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0016 | 0.0145 | 0.0217 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.024 | 0.4508 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.1035 | 0.2243 |
Echinococcus granulosus | jumonji domain containing protein | 0.0025 | 0.0329 | 0.0298 |
Entamoeba histolytica | hypothetical protein | 0.0014 | 0.0123 | 0.008 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0076 | 0.1318 | 0.1291 |
Schistosoma mansoni | hypothetical protein | 0.0523 | 1 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0024 | 0.0306 | 0.0614 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.1876 | 0.185 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.3031 | 0.6702 |
Onchocerca volvulus | 0.0019 | 0.0216 | 0.0095 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.004 | 0.0621 | 0.0591 |
Echinococcus multilocularis | peregrin | 0.0018 | 0.0192 | 0.0161 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0216 | 0.0185 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0016 | 0.0145 | 0.0217 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0046 | 0.0729 | 0.1942 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.004 | 0.0621 | 0.0888 |
Brugia malayi | CXXC zinc finger family protein | 0.0037 | 0.0555 | 0.117 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0059 | 0.0988 | 0.096 |
Brugia malayi | jmjC domain containing protein | 0.0059 | 0.0988 | 0.2137 |
Echinococcus multilocularis | cpg binding protein | 0.0039 | 0.0596 | 0.0566 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1035 | 0.1007 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.001 | 0.0032 | 0.0001 |
Leishmania major | importin beta-1 subunit, putative | 0.0014 | 0.0123 | 0.1544 |
Onchocerca volvulus | 0.0147 | 0.2701 | 1 | |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0013 | 0.0097 | 0.0145 |
Leishmania major | GTP-binding protein, putative | 0.0013 | 0.0097 | 0.1104 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0018 | 0.0188 | 0.0157 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0018 | 0.0188 | 0.0882 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0014 | 0.0123 | 0.806 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.003 | 0.0429 | 0.0399 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0018 | 0.0192 | 0.1365 |
Schistosoma mansoni | cpg binding protein | 0.0037 | 0.0555 | 0.0525 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0352 | 0.6669 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0018 | 0.0192 | 0.0161 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0088 | 0.1556 | 0.1546 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0216 | 0.0185 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.004 | 0.0621 | 0.0591 |
Giardia lamblia | PHD finger protein 15 | 0.0018 | 0.0192 | 0.0293 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0181 | 0.335 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0039 | 0.0596 | 0.0566 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.1035 | 0.2243 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0019 | 0.0216 | 0.0185 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0032 | 0.0001 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0013 | 0.0097 | 0.5764 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0046 | 0.0729 | 0.1942 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.1035 | 0.2243 |
Echinococcus granulosus | geminin | 0.0105 | 0.1876 | 0.185 |
Brugia malayi | Muscleblind-like protein | 0.0099 | 0.1759 | 0.3859 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0019 | 0.0216 | 0.1568 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0088 | 0.1556 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.3031 | 0.3009 |
Echinococcus granulosus | muscleblind protein | 0.0099 | 0.1759 | 0.1733 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.003 | 0.0429 | 0.0399 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Brugia malayi | RNA, U transporter 1 | 0.0051 | 0.0826 | 0.1775 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0013 | 0.0097 | 0.0145 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0014 | 0.0123 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.4508 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0012 | 0.0076 | 0.0044 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0018 | 0.0187 | 0.0156 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0565 | 0.1191 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0024 | 0.0306 | 0.0275 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0013 | 0.0097 | 0.0145 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.1035 | 0.1007 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0024 | 0.0306 | 0.0614 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0019 | 0.0216 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1414 | 0.3088 |
Echinococcus granulosus | peregrin | 0.0018 | 0.0192 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1759 | 0.3859 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0019 | 0.0216 | 0.0185 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0164 | 0.3031 | 0.6702 |
Trichomonas vaginalis | importin beta-1, putative | 0.0014 | 0.0123 | 0.0356 |
Plasmodium vivax | SET domain protein, putative | 0.0019 | 0.0216 | 0.0324 |
Plasmodium vivax | hypothetical protein, conserved | 0.0018 | 0.0192 | 0.0288 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.003 | 0.0429 | 0.0399 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0019 | 0.0216 | 0.0185 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0076 | 0.1318 | 0.1291 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1035 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0145 | 0.0252 |
Schistosoma mansoni | ran | 0.0013 | 0.0097 | 0.0065 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.004 | 0.0621 | 0.0591 |
Plasmodium falciparum | importin beta, putative | 0.0018 | 0.0188 | 0.0282 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0016 | 0.0145 | 0.0961 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0145 | 0.0252 |
Schistosoma mansoni | jumonji domain containing protein | 0.0047 | 0.0753 | 0.0723 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0523 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0145 | 0.1916 |
Schistosoma mansoni | hypothetical protein | 0.0105 | 0.1876 | 0.185 |
Onchocerca volvulus | Huntingtin homolog | 0.0081 | 0.1414 | 0.487 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.001 | 0.0032 | 0.0048 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.004 | 0.0621 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.003 | 0.0429 | 0.0399 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.007 | 0.1207 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.0018 | 0.0188 | 0.0157 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0024 | 0.0306 | 0.0275 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0076 | 0.1318 | 0.2874 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0046 | 0.0729 | 0.1942 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.2091 | 0.4601 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0046 | 0.0729 | 0.1942 |
Echinococcus multilocularis | geminin | 0.0105 | 0.1876 | 0.185 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0019 | 0.0216 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0192 | 0.0358 |
Brugia malayi | hypothetical protein | 0.0081 | 0.1414 | 0.3088 |
Echinococcus granulosus | cpg binding protein | 0.0039 | 0.0596 | 0.0566 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.003 | 0.0429 | 0.0399 |
Echinococcus granulosus | snurportin 1 | 0.019 | 0.3537 | 0.3516 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.003 | 0.0429 | 0.0888 |
Brugia malayi | Pre-SET motif family protein | 0.013 | 0.2356 | 0.5193 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0013 | 0.0097 | 0.5764 |
Brugia malayi | PHD-finger family protein | 0.0018 | 0.0192 | 0.0358 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.1318 | 0.1291 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0013 | 0.0097 | 0.0065 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.001 | 0.0032 | 0.0001 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0018 | 0.0188 | 0.0282 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0022 | 0.0266 | 0.0235 |
Schistosoma mansoni | ran | 0.0013 | 0.0097 | 0.0065 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0016 | 0.0145 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.1035 | 0.1007 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0013 | 0.0097 | 0.0145 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.004 | 0.0621 | 0.0591 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0018 | 0.0192 | 0.0161 |
Loa Loa (eye worm) | histone methyltransferase | 0.0012 | 0.0076 | 0.0099 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0059 | 0.0988 | 0.096 |
Schistosoma mansoni | cpg binding protein | 0.0039 | 0.0596 | 0.0566 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0076 | 0.1318 | 0.1291 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0024 | 0.0306 | 0.0275 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.003 | 0.0429 | 0.0399 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0016 | 0.0147 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.3537 | 0.3516 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.004 | 0.0621 | 0.5018 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0013 | 0.0097 | 0.0367 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0427 | 0.8125 | 0.8119 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0352 | 0.6669 | 0.5 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.0352 | 0.6669 | 1 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.0352 | 0.6669 | 1 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0013 | 0.0097 | 0.0554 |
Trichomonas vaginalis | ran, putative | 0.0013 | 0.0097 | 0.0278 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.1035 | 0.2243 |
Schistosoma mansoni | importin beta-1 | 0.0018 | 0.0188 | 0.0157 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.1035 | 0.2243 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0018 | 0.0192 | 0.1365 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0046 | 0.0729 | 0.1942 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0076 | 0.1318 | 0.1291 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.1318 | 0.1291 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.001 | 0.0032 | 0.0048 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.0352 | 0.6669 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0081 | 0.1414 | 0.487 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0016 | 0.0145 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0018 | 0.0192 | 0.0358 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.019 | 0.3537 | 0.3516 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0037 | 0.0555 | 0.117 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0088 | 0.1556 | 0.2296 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0016 | 0.0145 | 0.0217 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0076 | 0.1318 | 0.2874 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.1318 | 0.2874 |
Trypanosoma brucei | RNA helicase, putative | 0.0101 | 0.1806 | 1 |
Brugia malayi | RNA binding protein | 0.0061 | 0.1035 | 0.2243 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0016 | 0.0145 | 0.0636 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.1318 | 0.1291 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0079 | 0.1368 | 0.1341 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0013 | 0.0097 | 0.0065 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0018 | 0.0188 | 0.0882 |
Plasmodium falciparum | phd finger protein, putative | 0.0018 | 0.0192 | 0.0288 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.013 | 0.2356 | 0.5193 |
Echinococcus granulosus | GPCR family 2 | 0.0076 | 0.1318 | 0.1291 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0025 | 0.0329 | 0.0298 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0192 | 0.0161 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.2091 | 0.4601 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0216 | 0.0412 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0188 | 0.0348 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1035 | 0.1007 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0032 | 0.0001 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0018 | 0.0188 | 0.1332 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0012 | 0.0076 | 0.0044 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.0352 | 0.6669 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0014 | 0.0123 | 0.0356 |
Brugia malayi | hypothetical protein | 0.001 | 0.0037 | 0.0013 |
Brugia malayi | Importin beta-1 subunit | 0.0018 | 0.0188 | 0.035 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.1806 | 0.178 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0427 | 0.8125 | 0.8119 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0442 | 0.0917 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1759 | 0.3859 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.2091 | 0.4601 |
Trichomonas vaginalis | set domain proteins, putative | 0.0147 | 0.2701 | 0.806 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0099 | 0.1759 | 0.1733 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0018 | 0.0192 | 0.0161 |
Echinococcus multilocularis | muscleblind protein | 0.0099 | 0.1759 | 0.1733 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 0.1318 | 0.1291 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.003 | 0.0429 | 0.0888 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.024 | 0.4508 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0019 | 0.0216 | 0.0412 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0352 | 0.6669 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.024 | 0.4508 | 1 |
Onchocerca volvulus | 0.0037 | 0.0555 | 0.1448 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.003 | 0.0429 | 0.0399 |
Chlamydia trachomatis | oxoacyl-ACP synthase III | 0.0352 | 0.6669 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0188 | 0.035 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0427 | 0.8125 | 0.8119 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0181 | 0.335 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1035 | 0.1007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.1035 | 0.1007 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0181 | 0.335 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1414 | 0.3088 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.