Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0069 | 0.0075 | 0.0084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0849 | 0.3446 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0174 | 0.0504 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.021 | 0.0611 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0289 | 0.1026 | 0.2976 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0069 | 0.0075 | 0.0098 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0063 | 0.0047 | 0.0617 |
Plasmodium falciparum | plasmepsin VII | 0.0201 | 0.0644 | 0.1757 |
Schistosoma mansoni | dopamine-beta-monooxygenase | 0.0898 | 0.3657 | 0.3653 |
Brugia malayi | Cathepsin L-like precursor | 0.0069 | 0.0075 | 0.0098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.013 | 0.0337 | 0.0977 |
Plasmodium falciparum | plasmepsin II | 0.0849 | 0.3446 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0849 | 0.3446 | 0.4861 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0063 | 0.0047 | 0.0136 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0146 | 0.0406 | 0.2348 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.0303 | 0.1087 | 0.1515 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0201 | 0.0644 | 0.1824 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0163 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.0957 | 0.1344 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Plasmodium falciparum | plasmepsin V | 0.0201 | 0.0644 | 0.1757 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0201 | 0.0644 | 0.0902 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.016 | 0.0468 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0069 | 0.0075 | 0.0084 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0146 | 0.0406 | 0.0566 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0043 | 0.0037 |
Echinococcus multilocularis | phosphatidylinositol 4 kinase alpha | 0.0063 | 0.0047 | 0.0043 |
Trypanosoma brucei | phosphatidylinositol 4-kinase alpha, putative | 0.0063 | 0.0047 | 0.0617 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0069 | 0.0075 | 0.0098 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0173 | 0.0502 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0069 | 0.0075 | 0.0084 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0043 | 0.0037 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0043 | 0.0052 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Echinococcus granulosus | cathepsin b | 0.0146 | 0.0406 | 0.0552 |
Echinococcus multilocularis | cathepsin b | 0.0146 | 0.0406 | 0.0552 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0062 | 0.0043 | 0.0124 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.021 | 0.0611 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0146 | 0.0406 | 0.0401 |
Brugia malayi | Cathepsin L-like precursor | 0.0069 | 0.0075 | 0.0098 |
Brugia malayi | hypothetical protein | 0.0201 | 0.0644 | 0.0902 |
Brugia malayi | Cathepsin L-like precursor | 0.0069 | 0.0075 | 0.0098 |
Onchocerca volvulus | 0.0201 | 0.0644 | 1 | |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0146 | 0.0406 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0075 | 0.0098 |
Echinococcus granulosus | cathepsin l1 | 0.0069 | 0.0075 | 0.0084 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0417 | 0.1576 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0043 | 0.0052 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0069 | 0.0075 | 0.0084 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0062 | 0.0043 | 0.0124 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0146 | 0.0406 | 0.8626 |
Plasmodium vivax | aspartyl protease, putative | 0.0201 | 0.0644 | 0.1757 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0146 | 0.0406 | 0.0401 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.2367 | 1 | 1 |
Giardia lamblia | Phosphoinositide-3-kinase, class 3 | 0.0105 | 0.0229 | 0.3242 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0056 | 0.0019 | 0.0013 |
Plasmodium falciparum | plasmepsin VI | 0.0849 | 0.3446 | 1 |
Echinococcus granulosus | phosphatidylinositol 3 kinase catalytic subunit | 0.0063 | 0.0047 | 0.0043 |
Brugia malayi | Cathepsin L-like precursor | 0.0069 | 0.0075 | 0.0098 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0063 | 0.0047 | 0.0178 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Onchocerca volvulus | 0.0201 | 0.0644 | 1 | |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0849 | 0.3446 | 0.4861 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0333 | 0.1217 | 0.7652 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0056 | 0.0019 | 0.0056 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0201 | 0.0644 | 0.0902 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0146 | 0.0406 | 0.2484 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.0396 | 0.0551 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0062 | 0.0043 | 0.0038 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0043 | 0.0052 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0073 | 0.0094 | 0.1669 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0108 | 0.0243 | 0.0706 |
Plasmodium vivax | aspartyl protease, putative | 0.0201 | 0.0644 | 0.1757 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0075 | 0.036 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Entamoeba histolytica | hypothetical protein | 0.0333 | 0.1217 | 0.7652 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0063 | 0.0047 | 0.0041 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.016 | 0.0468 | 0.0462 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.016 | 0.0468 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0069 | 0.0075 | 0.0084 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0124 | 0.0313 | 0.0434 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0174 | 0.0504 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.013 | 0.0337 | 0.7096 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.013 | 0.0337 | 0.0977 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.016 | 0.0468 | 0.1357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Echinococcus granulosus | phosphatidylinositol 4 kinase alpha | 0.0063 | 0.0047 | 0.0043 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0163 | 0.0157 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.021 | 0.0611 |
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.0303 | 0.1087 | 0.1515 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.016 | 0.0468 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.0163 | 0.0222 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0775 | 0.3125 | 0.44 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0062 | 0.0043 | 0.0052 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.016 | 0.0468 | 0.0653 |
Echinococcus granulosus | expressed conserved protein | 0.0286 | 0.1011 | 0.1407 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0201 | 0.0644 | 0.1757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.0163 | 0.0222 |
Schistosoma mansoni | peptidylglycine monooxygenase | 0.0898 | 0.3657 | 0.3653 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0069 | 0.0075 | 0.0084 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0163 | 0.0157 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0206 | 0.0666 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0664 | 0.2647 | 0.3732 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.016 | 0.0468 | 0.0639 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0043 | 0.0052 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.016 | 0.0468 | 0.2751 |
Plasmodium falciparum | plasmepsin IV | 0.0849 | 0.3446 | 1 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.019 | 0.0598 | 0.3601 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0849 | 0.3446 | 0.3442 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0043 | 0.0052 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0062 | 0.0043 | 0.0124 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0043 | 0.0037 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0273 | 0.0957 | 0.1344 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Loa Loa (eye worm) | ctsf protein | 0.0069 | 0.0075 | 0.0098 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0082 | 0.0131 | 0.2489 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.016 | 0.0468 | 0.1357 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0062 | 0.0043 | 0.0529 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0417 | 0.1576 | 0.4574 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.016 | 0.0468 | 0.1357 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0146 | 0.0406 | 0.1178 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0062 | 0.0043 | 0.0152 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0122 | 0.0304 | 0.0831 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0174 | 0.0504 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0069 | 0.0075 | 0.0084 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0146 | 0.0406 | 0.2487 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0111 | 0.0257 | 0.0746 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0075 | 0.036 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Loa Loa (eye worm) | hypothetical protein | 0.0898 | 0.3657 | 0.5159 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0146 | 0.0406 | 0.0401 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0043 | 0.0037 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0163 | 0.0157 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0849 | 0.3446 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0146 | 0.0406 | 0.0565 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0069 | 0.0075 | 0.0098 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0417 | 0.1576 | 0.4574 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0173 | 0.0502 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.0063 | 0.0047 | 0.0081 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.016 | 0.0468 | 0.0653 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0062 | 0.0043 | 0.0037 |
Echinococcus multilocularis | Zinc finger, PHD finger | 0.0063 | 0.0047 | 0.0043 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.0063 | 0.0047 | 0.0041 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0062 | 0.0043 | 0.0038 |
Echinococcus multilocularis | cysteine protease | 0.0069 | 0.0075 | 0.0084 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0062 | 0.0043 | 0.0124 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0146 | 0.0406 | 0.1178 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0146 | 0.0406 | 0.1178 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0163 | 0.0207 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0075 | 0.036 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0069 | 0.0075 | 0.0084 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0775 | 0.3125 | 0.3121 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Brugia malayi | Cathepsin L-like precursor | 0.0069 | 0.0075 | 0.0098 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0173 | 0.0502 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0207 | 0.06 |
Plasmodium falciparum | plasmepsin III | 0.0201 | 0.0644 | 0.1757 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0069 | 0.0075 | 0.0186 |
Brugia malayi | hypothetical protein | 0.0664 | 0.2647 | 0.3732 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0207 | 0.06 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0417 | 0.1576 | 1 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0636 | 0.2524 | 0.3549 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0849 | 0.3446 | 0.4853 |
Echinococcus granulosus | peptidyl glycine alpha amidating monooxygenase | 0.1691 | 0.7083 | 1 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0201 | 0.0644 | 0.0902 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0395 | 0.1483 | 0.939 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein | 0.0456 | 0.1746 | 0.2458 |
Schistosoma mansoni | peptidyl-glycine monooxygenase | 0.1691 | 0.7083 | 0.7081 |
Leishmania major | cysteine peptidase A (CPA) | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Giardia lamblia | GTOR | 0.016 | 0.0468 | 0.6929 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0898 | 0.3657 | 0.5159 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0069 | 0.0075 | 0.036 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0146 | 0.0406 | 0.04 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0062 | 0.0043 | 0.0124 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0062 | 0.0043 | 0.0529 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0174 | 0.0504 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0849 | 0.3446 | 0.4853 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0063 | 0.0047 | 0.0136 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0201 | 0.0644 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.1691 | 0.7083 | 1 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.1691 | 0.7083 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Brugia malayi | SH2 domain containing protein | 0.1191 | 0.4921 | 0.6945 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0063 | 0.0047 | 0.0178 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0062 | 0.0043 | 0.0052 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.016 | 0.0468 | 0.288 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0069 | 0.0075 | 0.0186 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0636 | 0.2524 | 0.3549 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0069 | 0.0075 | 0.0069 |
Entamoeba histolytica | cysteine protease, putative | 0.0069 | 0.0075 | 0.0186 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.016 | 0.0468 | 0.288 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0055 | 0.0016 | 0.001 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0692 | 0.2766 | 0.39 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0163 | 0.0207 |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.0063 | 0.0047 | 0.0617 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0273 | 0.0957 | 0.1331 |
Plasmodium falciparum | plasmepsin I | 0.0849 | 0.3446 | 1 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0417 | 0.1576 | 0.4574 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.013 | 0.0337 | 0.2044 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0043 | 0.0037 |
Brugia malayi | Pepsin A precursor | 0.0201 | 0.0644 | 0.0902 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0417 | 0.1576 | 1 |
Toxoplasma gondii | aspartyl protease | 0.0201 | 0.0644 | 0.1824 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0849 | 0.3446 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0069 | 0.0075 | 0.0098 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0359 | 0.1325 | 0.1865 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0163 | 0.0207 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.0063 | 0.0047 | 0.0058 |
Echinococcus granulosus | cathepsin b | 0.0146 | 0.0406 | 0.0552 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0273 | 0.0957 | 0.1331 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0201 | 0.0644 | 0.1824 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.0644 | 0.0902 |
Echinococcus multilocularis | peptidyl glycine alpha amidating monooxygenase | 0.1691 | 0.7083 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0069 | 0.0075 | 0.0164 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0062 | 0.0043 | 0.0529 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.013 | 0.0337 | 0.0977 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0069 | 0.0075 | 0.036 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.016 | 0.0468 | 0.0639 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.013 | 0.0337 | 0.0977 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.0063 | 0.0047 | 0.0081 |
Brugia malayi | sulfakinin receptor protein | 0.0664 | 0.2647 | 0.3732 |
Plasmodium vivax | vivapain-2 | 0.0069 | 0.0075 | 0.0084 |
Plasmodium vivax | vivapain-2 | 0.0069 | 0.0075 | 0.0084 |
Loa Loa (eye worm) | cathepsin B | 0.0056 | 0.0019 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0286 | 0.1011 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.0644 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.1191 | 0.4921 | 0.6945 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0849 | 0.3446 | 1 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0289 | 0.1026 | 0.2976 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0201 | 0.0644 | 0.1757 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.016 | 0.0468 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0043 | 0.0037 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0417 | 0.1576 | 0.2219 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.0063 | 0.0047 | 0.0058 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0043 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0406 | 0.0566 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.013 | 0.0337 | 0.0977 |
Loa Loa (eye worm) | cysteine protease | 0.0069 | 0.0075 | 0.0098 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Plasmodium falciparum | plasmepsin IX | 0.0201 | 0.0644 | 0.1757 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0442 | 0.1688 | 0.2377 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0138 | 0.0374 | 0.1086 |
Plasmodium vivax | plasmepsin IV, putative | 0.0849 | 0.3446 | 1 |
Trichomonas vaginalis | phosphatidylinositol 4-kinase, putative | 0.0063 | 0.0047 | 0.0136 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Plasmodium falciparum | plasmepsin X | 0.0201 | 0.0644 | 0.1757 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0201 | 0.0644 | 0.0902 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0043 | 0.0037 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0069 | 0.0075 | 0.1252 |
Echinococcus multilocularis | cathepsin b | 0.0146 | 0.0406 | 0.0552 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0062 | 0.0043 | 0.0529 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0124 | 0.0313 | 0.1885 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0055 | 0.0016 | 0.001 |
Echinococcus multilocularis | cysteine protease | 0.0069 | 0.0075 | 0.0084 |
Brugia malayi | Cathepsin L-like precursor | 0.0069 | 0.0075 | 0.0098 |
Leishmania major | cathepsin L-like protease | 0.0069 | 0.0075 | 0.1252 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.013 | 0.0337 | 0.7096 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0122 | 0.0304 | 0.0882 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0775 | 0.3125 | 0.44 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0201 | 0.0644 | 0.0639 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0069 | 0.0075 | 0.0218 |
Echinococcus multilocularis | expressed conserved protein | 0.0286 | 0.1011 | 0.1407 |
Plasmodium vivax | aspartyl protease, putative | 0.0201 | 0.0644 | 0.1757 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0069 | 0.0075 | 0.0084 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0146 | 0.0406 | 0.0401 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.016 | 0.0468 | 0.2751 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0062 | 0.0043 | 0.0152 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0069 | 0.0075 | 0.0069 |
Brugia malayi | hypothetical protein | 0.0201 | 0.0644 | 0.0902 |
Plasmodium vivax | plasmepsin V, putative | 0.0201 | 0.0644 | 0.1757 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 362 nM | In vitro inhibitory concentration of the compound against Plasmodium falciparum | ChEMBL. | 15887971 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.