Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | methionyl aminopeptidase 2 | 0.0363 | 0.7799 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0072 | 0.0971 | 0.2181 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0363 | 0.7799 | 1 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0363 | 0.7799 | 1 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0045 | 0.0351 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0058 | 0.004 |
Mycobacterium ulcerans | lipase LipD | 0.0072 | 0.0971 | 0.2181 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Loa Loa (eye worm) | metallopeptidase family M24 containing protein | 0.0045 | 0.0351 | 0.0417 |
Giardia lamblia | Methionine aminopeptidase | 0.0363 | 0.7799 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.036 | 0.0461 |
Plasmodium vivax | methionine aminopeptidase 1c, putative | 0.0045 | 0.0351 | 0.0417 |
Toxoplasma gondii | hypothetical protein | 0.0051 | 0.0489 | 0.0594 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0971 | 0.1215 |
Echinococcus multilocularis | FACT complex subunit SPT16 | 0.0045 | 0.0351 | 0.0417 |
Onchocerca volvulus | FACT complex subunit SPT16 homolog | 0.0045 | 0.0351 | 0.0417 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0053 | 0.0528 | 0.0237 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0072 | 0.0971 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0351 | 0.0417 |
Schistosoma mansoni | chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Wolbachia endosymbiont of Brugia malayi | Xaa-Pro aminopeptidase | 0.0045 | 0.0351 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0053 | 0.0528 | 0.0645 |
Echinococcus granulosus | geminin | 0.0169 | 0.3248 | 0.4165 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0045 | 0.0351 | 0.5 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0316 | 0.6694 | 0.8519 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0053 | 0.0528 | 0.0237 |
Plasmodium vivax | peptidase, putative | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0316 | 0.6694 | 0.8519 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0053 | 0.0528 | 0.0677 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0528 | 0.0237 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.036 | 0.0461 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0971 | 0.0642 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0053 | 0.0528 | 0.0645 |
Trichomonas vaginalis | set domain proteins, putative | 0.0248 | 0.5098 | 0.6373 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Echinococcus granulosus | xaa Pro dipeptidase | 0.0045 | 0.0351 | 0.045 |
Schistosoma mansoni | Xaa-Pro dipeptidase (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0971 | 0.0832 |
Onchocerca volvulus | Dipeptidase C homolog | 0.0045 | 0.0351 | 0.0417 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0708 | 0.1257 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0058 | 0.004 |
Trypanosoma brucei | methionine aminopeptidase 2, putative | 0.0363 | 0.7799 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.2797 | 0.3284 |
Brugia malayi | follicle stimulating hormone receptor | 0.023 | 0.4685 | 0.5993 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0351 | 0.0417 |
Onchocerca volvulus | 0.0072 | 0.0971 | 0.1215 | |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0027 | 0.0034 |
Trypanosoma cruzi | Metallopeptidase family M24, putative | 0.0045 | 0.0351 | 0.0021 |
Brugia malayi | DNA-binding protein, 42 kDa containing protein | 0.0045 | 0.0351 | 0.0417 |
Brugia malayi | initiation factor 2-associated protein. | 0.0363 | 0.7799 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0114 | 0.1965 | 0.2494 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Schistosoma mansoni | peptidase | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0053 | 0.0528 | 0.0257 |
Entamoeba histolytica | methionine aminopeptidase, putative | 0.0363 | 0.7799 | 1 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0045 | 0.0351 | 0.0417 |
Toxoplasma gondii | creatinase domain-containing protein | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma cruzi | Metallopeptidase family M24, putative | 0.0045 | 0.0351 | 0.0021 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0971 | 0.1215 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0045 | 0.0351 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0708 | 0.0877 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0971 | 0.1215 |
Schistosoma mansoni | proliferation-associated protein 2G4 38kDa (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.036 | 0.0428 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0045 | 0.0351 | 0.0021 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.036 | 0.0428 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0316 | 0.6694 | 0.8519 |
Echinococcus multilocularis | xaa Pro dipeptidase | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma brucei | Metallopeptidase family M24, putative | 0.0045 | 0.0351 | 0.0021 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0971 | 0.1215 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.023 | 0.4685 | 0.5993 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0114 | 0.1965 | 0.2494 |
Onchocerca volvulus | 0.0045 | 0.0351 | 0.0417 | |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0971 | 0.1215 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0971 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0971 | 0.1215 |
Onchocerca volvulus | 0.0248 | 0.5098 | 0.6525 | |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0971 | 0.1215 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0218 | 0.4394 | 0.5619 |
Echinococcus multilocularis | methionine aminopeptidase, type I | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma cruzi | aminopeptidase P, putative | 0.0045 | 0.0351 | 0.0021 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0708 | 0.1257 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0971 | 0.1215 |
Treponema pallidum | aminopeptidase P | 0.0045 | 0.0351 | 0.5 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0072 | 0.0971 | 0.0642 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0072 | 0.0971 | 0.0642 |
Toxoplasma gondii | methionine aminopeptidase 2, putative | 0.0363 | 0.7799 | 1 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0363 | 0.7799 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0971 | 0.1215 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0708 | 0.0877 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Onchocerca volvulus | 0.0072 | 0.0971 | 0.1215 | |
Echinococcus multilocularis | Proliferation associated protein 2G4 | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.015 | 0.2797 | 0.3298 |
Trypanosoma brucei | protein kinase, putative | 0.0053 | 0.0528 | 0.0257 |
Echinococcus multilocularis | xaa Pro dipeptidase | 0.0045 | 0.0351 | 0.0417 |
Plasmodium falciparum | methionine aminopeptidase 2 | 0.0363 | 0.7799 | 1 |
Toxoplasma gondii | peptidase D, putative | 0.0045 | 0.0351 | 0.0417 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.036 | 0.0428 |
Schistosoma mansoni | aminopeptidase P1 (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0528 | 0.0237 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0072 | 0.0971 | 0.0642 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0045 | 0.0351 | 0.045 |
Toxoplasma gondii | transcriptional elongation factor FACT140 | 0.0045 | 0.0351 | 0.0417 |
Plasmodium vivax | proliferation-associated protein 2g4, putative | 0.0045 | 0.0351 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0351 | 0.0417 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0114 | 0.1965 | 0.2494 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.041 | 0.0493 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0316 | 0.6694 | 0.8516 |
Mycobacterium leprae | conserved hypothetical protein | 0.0072 | 0.0971 | 1 |
Leishmania major | methionine aminopeptidase 2, putative | 0.0363 | 0.7799 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0971 | 0.2181 |
Brugia malayi | MAP kinase sur-1 | 0.0053 | 0.0528 | 0.0645 |
Echinococcus granulosus | xaa pro aminopeptidase | 0.0045 | 0.0351 | 0.045 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.036 | 0.0428 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0054 | 0.0563 | 0.0305 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0971 | 0.0832 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.015 | 0.2797 | 0.3298 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0971 | 0.1245 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0072 | 0.0971 | 0.0642 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0971 | 0.0851 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0971 | 0.1215 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.041 | 0.0493 |
Schistosoma mansoni | methionyl aminopeptidase 2 (M24 family) | 0.0363 | 0.7799 | 1 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0971 | 0.1215 |
Mycobacterium ulcerans | hypothetical protein | 0.0166 | 0.3193 | 1 |
Echinococcus granulosus | methionyl aminopeptidase 2 | 0.0363 | 0.7799 | 1 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0045 | 0.0351 | 0.0021 |
Loa Loa (eye worm) | DNA-binding protein | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0971 | 0.0851 |
Trypanosoma brucei | Xaa-Pro aminopeptidase, putative | 0.0045 | 0.0351 | 0.0021 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0971 | 0.1215 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0528 | 0.0237 |
Echinococcus granulosus | methionine aminopeptidase type I | 0.0045 | 0.0351 | 0.045 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0053 | 0.0528 | 0.0645 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0708 | 0.0479 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0971 | 0.0832 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0971 | 0.0642 |
Mycobacterium leprae | Probable lipase LipE | 0.0072 | 0.0971 | 1 |
Plasmodium vivax | methionine aminopeptidase 2, putative | 0.0363 | 0.7799 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0971 | 0.0851 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0053 | 0.0528 | 0.0645 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.036 | 0.0428 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0363 | 0.7799 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0971 | 0.1215 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0072 | 0.0971 | 0.0642 |
Echinococcus granulosus | FACT complex subunit SPT16 | 0.0045 | 0.0351 | 0.045 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0363 | 0.7799 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0045 | 0.0351 | 0.0021 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0528 | 0.0257 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.036 | 0.0428 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0053 | 0.0528 | 0.0645 |
Plasmodium vivax | FACT complex subunit SPT16, putative | 0.0045 | 0.0351 | 0.0417 |
Echinococcus granulosus | Proliferation associated protein 2G4 | 0.0045 | 0.0351 | 0.045 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0045 | 0.0351 | 0.5 |
Toxoplasma gondii | methionine aminopeptidase | 0.0045 | 0.0351 | 0.0417 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0053 | 0.0528 | 0.0677 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0971 | 0.0832 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0971 | 0.1215 |
Trypanosoma brucei | Facilitates chromatin transcription complex subunit spt16 | 0.0045 | 0.0351 | 0.0021 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0045 | 0.0351 | 0.0417 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0053 | 0.0528 | 0.0237 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.036 | 0.0428 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0053 | 0.0528 | 0.0237 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0053 | 0.0528 | 0.0257 |
Echinococcus multilocularis | xaa pro aminopeptidase | 0.0045 | 0.0351 | 0.0417 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0971 | 0.0832 |
Echinococcus granulosus | xaa Pro dipeptidase | 0.0045 | 0.0351 | 0.045 |
Trypanosoma cruzi | Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative | 0.0045 | 0.0351 | 0.0021 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0053 | 0.0528 | 0.0257 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0363 | 0.7799 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0971 | 0.1215 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.3248 | 0.4144 |
Toxoplasma gondii | methionine aminopeptidase | 0.0045 | 0.0351 | 0.0417 |
Toxoplasma gondii | proliferation-associated protein 2G4, putative | 0.0045 | 0.0351 | 0.0417 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0708 | 0.0877 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0363 | 0.7799 | 1 |
Echinococcus multilocularis | Xaa Pro aminopeptidase 3 | 0.0045 | 0.0351 | 0.0417 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0971 | 0.0832 |
Onchocerca volvulus | Methionine aminopeptidase 2 homolog | 0.0363 | 0.7799 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0045 | 0.0351 | 0.0417 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.3248 | 0.4144 |
Schistosoma mansoni | proliferation-associated protein 2G4 38kDa (M24 family) | 0.0045 | 0.0351 | 0.0417 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0166 | 0.3193 | 0.2945 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0072 | 0.0971 | 0.2181 |
Mycobacterium ulcerans | beta-lactamase | 0.0072 | 0.0971 | 0.2181 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0072 | 0.0971 | 0.0642 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0045 | 0.0351 | 0.0417 |
Loa Loa (eye worm) | initiation factor 2-associated protein | 0.0363 | 0.7799 | 1 |
Echinococcus multilocularis | geminin | 0.0169 | 0.3248 | 0.4144 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0971 | 0.0832 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0708 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0971 | 0.1215 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0058 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.041 | 0.0493 |
Trypanosoma cruzi | aminopeptidase P1, putative | 0.0045 | 0.0351 | 0.0021 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0708 | 0.0877 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0053 | 0.0528 | 0.0257 |
Chlamydia trachomatis | aminopeptidase P | 0.0045 | 0.0351 | 0.5 |
Onchocerca volvulus | 0.0072 | 0.0971 | 0.1215 | |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0045 | 0.0351 | 0.0021 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0045 | 0.0351 | 0.0021 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0045 | 0.0351 | 0.0417 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0971 | 0.1215 |
Brugia malayi | Pre-SET motif family protein | 0.0218 | 0.4394 | 0.5619 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0708 | 0.1257 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0708 | 0.0908 |
Echinococcus granulosus | Xaa Pro aminopeptidase 3 | 0.0045 | 0.0351 | 0.045 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0045 | 0.0351 | 0.0417 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0045 | 0.0351 | 0.0417 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.041 | 0.0493 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 6.6 uM | In vitro inhibition of thromboxane A2 production in rat platelet-rich plasma. | ChEMBL. | 2724303 |
Inhibition (functional) | = 51 % | Inhibition of thromboxane B2 production in whole blood of rat 75 min after intravenous injection of compound at 0.1 mg/kg | ChEMBL. | 2724303 |
Inhibition (functional) | = 60 % | Inhibition of thromboxane B2 production in whole blood of rat 45 min after intravenous injection of compound at 0.1 mg/kg | ChEMBL. | 2724303 |
Inhibition (functional) | = 73 % | Inhibition of thromboxane B2 production in whole blood of rat 15 min after intravenous injection of compound at 0.1 mg/kg | ChEMBL. | 2724303 |
Inhibition (functional) | = 74 % | Inhibition of thromboxane B2 production in whole blood of rats, 6 hr after a peroral dose of 1.0 mg/kg | ChEMBL. | 2724303 |
Inhibition (functional) | = 90 % | Inhibition of thromboxane B2 production in whole blood of rats, 3h after a peroral dose of 1.0 mg/kg | ChEMBL. | 2724303 |
Inhibition (functional) | = 95 % | Inhibition of thromboxane B2 production in whole blood of rats 1 hr following 1 mg/kg p.o. | ChEMBL. | 2724303 |
x fold (functional) | = 3.57 | Increase in serum prostaglandin I2 levels in incubated whole blood from rats, 1 hr following 1 mg/kg p.o. | ChEMBL. | 2724303 |
x fold (functional) | = 6.93 | Enhancement of prostaglandin E2 levels in serum of incubated whole blood at 1 hr after an oral dose of 1 mg/kg | ChEMBL. | 2724303 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.