Detailed information for compound 553880

Basic information

Technical information
  • TDR Targets ID: 553880
  • Name: N-(3-chloro-4-methyl-phenyl)-2-methyl-pentana mide
  • MW: 239.741 | Formula: C13H18ClNO
  • H donors: 1 H acceptors: 1 LogP: 4.03 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(C(=O)Nc1ccc(c(c1)Cl)C)C
  • InChi: 1S/C13H18ClNO/c1-4-5-10(3)13(16)15-11-7-6-9(2)12(14)8-11/h6-8,10H,4-5H2,1-3H3,(H,15,16)
  • InChiKey: WGVWLKXZBUVUAM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-chloro-4-methylphenyl)-2-methylpentanamide
  • N-(3-chloro-4-methyl-phenyl)-2-methyl-valeramide
  • solan
  • 2307-68-8
  • NCGC00160659-01
  • ST043946
  • 33384_RIEDEL
  • N-(3-Chloro-4-methylphenyl)-2-methyl-pentanamide
  • 3'-Chloro-2-methyl-p-valerotoluidide
  • BRN 2722779
  • CMMP
  • Caswell No. 800
  • Chlorpentan
  • Dakuron
  • Dutom
  • EINECS 218-988-9
  • EPA Pesticide Chemical Code 020901
  • FMC 4512
  • Hortox
  • N-(3- Chloro-4-methylphenyl)-2-methylpentanamide
  • N-(3-Chlor-methylphenyl)-2-methylpentanamid [German]
  • N-(3-Chloro-4-methylphenyl)-2-methylpentamide
  • N-(3-Chloro-p-tolyl)-2-methylvaleramide
  • Niagara 4512
  • Pentachlore
  • Pentanamide, N-(3-chloro-4-methylphenyl)-2-methyl-
  • Pentanochlor
  • Pentanochlor [BSI:ISO]
  • Pentanochlore [ISO-French]
  • Solane
  • p-Valerotoluidide, 3'-chloro-2-methyl-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0172 0.1147
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Mycobacterium leprae PROBABLE METHYLTRANSFERASE 0.0058 0.0522 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.0922 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0339 0.0326
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0102 0.0505
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0172 0.1031
Brugia malayi Niemann-Pick C1 protein precursor 0.0118 0.1153 0.1101
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0339 0.1443
Echinococcus granulosus histone acetyltransferase KAT2B 0.0096 0.0925 0.0904
Plasmodium vivax SET domain protein, putative 0.0029 0.0211 0.1494
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0086 0.5
Leishmania major hypothetical protein, conserved 0.0025 0.0172 0.1313
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0102 0.0505
Loa Loa (eye worm) beta-lactamase 0.0041 0.0339 0.0326
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0102 0.0435
Loa Loa (eye worm) hypothetical protein 0.0058 0.0522 0.0509
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0339 0.0509
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0339 0.0509
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0147 0.1028
Echinococcus multilocularis protein dispatched 1 0.0058 0.0515 0.0493
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0211 0.0268
Mycobacterium ulcerans beta-lactamase 0.0041 0.0339 0.0482
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0102 0.0079
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0418 0.0361
Brugia malayi hypothetical protein 0.0016 0.0077 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0418 0.0404
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0922 0.1282
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0147 0.1028
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0102 0.0079
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0102 0.0044
Wolbachia endosymbiont of Brugia malayi O-methyltransferase 0.0058 0.0522 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0102 0.07
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0339 0.3021
Loa Loa (eye worm) hypothetical protein 0.0041 0.0339 0.0326
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.006
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0172 0.0852
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0922 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0147 0.0153
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0172 0.1147
Leishmania major hypothetical protein, conserved 0.0041 0.0339 0.3247
Mycobacterium ulcerans O-methyltransferase 0.0563 0.5872 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0017 0.0086 0.0046
Schistosoma mansoni hypothetical protein 0.0577 0.6022 0.8557
Mycobacterium ulcerans lipase LipD 0.0041 0.0339 0.0482
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0255 0.0197
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0102 0.0435
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0339 0.1443
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0147 0.0153
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0211 0.0268
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0339 0.3388
Loa Loa (eye worm) hypothetical protein 0.0041 0.0339 0.0326
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Mycobacterium leprae Probable lipase LipE 0.0041 0.0339 0.5116
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0339 0.0316
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0147 0.0433
Mycobacterium ulcerans hypothetical protein 0.0023 0.0147 0.0153
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0147 0.0153
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0102 0.0505
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0065 0.0007
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.0922 0.0901
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0102 0.0079
Echinococcus granulosus Niemann Pick C1 protein 0.0168 0.1689 0.167
Mycobacterium tuberculosis Probable catechol-O-methyltransferase 0.0504 0.5252 1
Schistosoma mansoni hypothetical protein 0.0049 0.042 0.0565
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0418 0.0404
Trichomonas vaginalis esterase, putative 0.0041 0.0339 0.1443
Echinococcus granulosus Niemann Pick C1 protein 0.0118 0.1153 0.1132
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.0922 0.0869
Schistosoma mansoni DNA polymerase eta 0.0019 0.0102 0.0113
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0147 0.1028
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0172 0.1313
Echinococcus multilocularis geminin 0.0577 0.6022 0.6013
Schistosoma mansoni hypothetical protein 0.0033 0.0255 0.033
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0339 0.1443
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.02 0.0177
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0102 0.0044
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0102 0.0052
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.006
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0339 0.0316
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0147 0.0153
Entamoeba histolytica acetyltransferase, GNAT family 0.0088 0.084 0.7021
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0418 0.0361
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0051 0.0439 0.0426
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0102 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Echinococcus multilocularis protein patched 0.0051 0.0439 0.0417
Brugia malayi hypothetical protein 0.0025 0.0172 0.0114
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0339 0.3247
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0096 0.0925 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0263 0.2692 0.5054
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0059 0.0045
Loa Loa (eye worm) acetyltransferase 0.0328 0.3379 0.337
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0102 0.0501
Mycobacterium tuberculosis Conserved protein 0.0041 0.0339 0.0509
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0102 0.0218
Echinococcus granulosus geminin 0.0577 0.6022 0.6013
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0065 0.0007
Schistosoma mansoni hypothetical protein 0.0049 0.042 0.0565
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0211 0.0268
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0211 0.0268
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.0922 0.0901
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0102 0.0505
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0147 0.0089
Echinococcus multilocularis Niemann Pick C1 protein 0.0168 0.1689 0.167
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0147 0.0153
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0102 0.0075
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0147 0.0139
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0211 0.0188
Echinococcus granulosus GPCR family 2 0.0015 0.0065 0.0042
Echinococcus multilocularis GPCR, family 2 0.0015 0.0065 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0147 0.0153
Mycobacterium tuberculosis Conserved protein 0.0041 0.0339 0.0509
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0339 0.0482
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0102 0.0505
Loa Loa (eye worm) hypothetical protein 0.0062 0.056 0.0547
Loa Loa (eye worm) O-methyltransferase 0.0058 0.0522 0.0509
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2053 0.2042
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0096 0.0925 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0065 0.0042
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0072
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0102 0.0703
Onchocerca volvulus 0.0231 0.235 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0102 0.0089
Echinococcus multilocularis muscleblind protein 0.0952 1 1
Onchocerca volvulus 0.0029 0.0211 0.0288
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0339 0.1443
Brugia malayi O-methyltransferase family protein 0.0058 0.0522 0.0466
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0339 0.045
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0102 0.0703
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0147 0.0433
Onchocerca volvulus 0.0058 0.0522 0.1701
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0339 0.3247
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Echinococcus multilocularis dna polymerase eta 0.0019 0.0102 0.0079
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0102 0.0113
Schistosoma mansoni o-methyltransferase 0.0058 0.0522 0.0711
Schistosoma mansoni o-methyltransferase 0.0058 0.0522 0.0711
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0102 0.0051
Brugia malayi Pre-SET motif family protein 0.0029 0.0211 0.0153
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0339 0.0509
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0065 0.0042
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0339 0.0482
Mycobacterium tuberculosis Conserved protein 0.0041 0.0339 0.0509
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0147 0.0433
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0065 0.0042
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0328 0.3379 0.3364
Brugia malayi beta-lactamase family protein 0.0041 0.0339 0.0282
Echinococcus granulosus expressed conserved protein 0.0111 0.1077 0.1056
Echinococcus multilocularis sterol regulatory element binding protein 0.0051 0.0439 0.0417
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0102 0.0113
Onchocerca volvulus 0.0041 0.0339 0.087
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0147 0.0153
Brugia malayi O-methyltransferase family protein 0.0058 0.0522 0.0466
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0339 0.0282
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0072
Trichomonas vaginalis bromodomain-containing protein, putative 0.0096 0.0925 0.3935
Onchocerca volvulus 0.0041 0.0339 0.087
Onchocerca volvulus 0.0058 0.0522 0.1701
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0339 0.0509
Brugia malayi CHE-14 protein 0.0051 0.0439 0.0383
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0102 0.0703
Loa Loa (eye worm) hypothetical protein 0.0023 0.0147 0.0134
Trypanosoma brucei polo-like protein kinase 0.0096 0.0922 1
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0102 0.0079
Brugia malayi acetyltransferase, GNAT family protein 0.0328 0.3379 0.334
Echinococcus multilocularis microtubule associated protein 2 0.0672 0.7033 0.7026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0102 0.0501
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0096 0.0925 0.3935
Schistosoma mansoni o-methyltransferase 0.0058 0.0522 0.0711
Schistosoma mansoni ap endonuclease 0.0019 0.0102 0.0112
Echinococcus granulosus dna polymerase eta 0.0019 0.0102 0.0079
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.1136 0.1124
Loa Loa (eye worm) hypothetical protein 0.0041 0.0339 0.0326
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0072
Toxoplasma gondii ABC1 family protein 0.0041 0.0339 0.2882
Loa Loa (eye worm) hypothetical protein 0.0051 0.0439 0.0426
Schistosoma mansoni hypothetical protein 0.0049 0.042 0.0565
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Loa Loa (eye worm) hypothetical protein 0.0041 0.0339 0.0326
Loa Loa (eye worm) hypothetical protein 0.0041 0.0339 0.0326
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0147 0.0139
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0102 0.0075
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0096 0.0925 1
Schistosoma mansoni patched 1 0.0051 0.0439 0.0593
Brugia malayi O-methyltransferase 0.0058 0.0522 0.0466
Schistosoma mansoni niemann-pick C1 (NPC1) 0.012 0.1172 0.1639
Brugia malayi beta-lactamase 0.0041 0.0339 0.0282
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0339 0.0326
Loa Loa (eye worm) hypothetical protein 0.0023 0.0147 0.0134
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0102 0.0434
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0102 0.0079
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0339 0.0509
Leishmania major DNA polymerase kappa, putative 0.0019 0.0102 0.0505
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0339 0.045
Schistosoma mansoni o-methyltransferase 0.0058 0.0522 0.0711
Brugia malayi beta-lactamase family protein 0.0041 0.0339 0.0282
Leishmania major DNA polymerase eta, putative 0.0019 0.0102 0.0505
Mycobacterium ulcerans methyltransferase 0.0058 0.0522 0.0797
Schistosoma mansoni hypothetical protein 0.0049 0.042 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0439 0.1868
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0102 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0102 0.0505
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0059 0.0209
Loa Loa (eye worm) hypothetical protein 0.0952 1 1
Trypanosoma brucei unspecified product 0.0019 0.0102 0.0703
Schistosoma mansoni microtubule-associated protein tau 0.0672 0.7033 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0086 0.0019
Loa Loa (eye worm) hypothetical protein 0.0952 1 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0922 0.7806
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0211 0.0188
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0328 0.3379 0.4787
Mycobacterium ulcerans hypothetical protein 0.0041 0.0339 0.0482
Giardia lamblia DINP protein human, muc B family 0.0019 0.0102 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0407 0.1733
Schistosoma mansoni hypothetical protein 0.0577 0.6022 0.8557
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0102 0.0089
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.0922 0.3517
Echinococcus granulosus muscleblind protein 0.0952 1 1
Echinococcus multilocularis expressed conserved protein 0.0111 0.1077 0.1056
Echinococcus granulosus sterol regulatory element binding protein 0.0051 0.0439 0.0417
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.1136 0.1124
Brugia malayi Pre-SET motif family protein 0.0203 0.2053 0.2006
Echinococcus multilocularis muscleblind protein 1 0.0952 1 1
Giardia lamblia Kinase, PLK 0.0096 0.0922 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0211 0.0197
Loa Loa (eye worm) hypothetical protein 0.0118 0.1153 0.1141
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0102 0.0703
Brugia malayi O-methyltransferase family protein 0.0058 0.0522 0.0466
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0211 0.1324
Echinococcus granulosus Protein patched homolog 1 0.0051 0.0439 0.0417
Echinococcus granulosus dna polymerase kappa 0.0019 0.0102 0.0079
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0211 0.0188
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0072
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0118 0.1153 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0102 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0147 0.0089
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0147 0.0089
Schistosoma mansoni ap endonuclease 0.0019 0.0102 0.0112
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0339 0.5116
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0172 0.1494
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0339 0.1443
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0102 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0086 0.0072
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0059 0.0045
Loa Loa (eye worm) hypothetical protein 0.0015 0.0065 0.0052
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0102 0.0434
Onchocerca volvulus 0.0041 0.0339 0.087
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0065 0.0052
Echinococcus granulosus microtubule associated protein 2 0.0672 0.7033 0.7026
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0102 0.0044
Plasmodium falciparum histone acetyltransferase GCN5 0.0088 0.084 1
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0339 0.0509
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Echinococcus granulosus histone acetyltransferase KAT2B 0.0318 0.3282 0.3266
Loa Loa (eye worm) hypothetical protein 0.0033 0.0255 0.0241
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0065 0.0042
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.0922 0.091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0172 0.0159
Giardia lamblia Histone acetyltransferase GCN5 0.0088 0.084 0.8994
Mycobacterium tuberculosis Probable methyltransferase 0.0058 0.0522 0.0863
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0339 0.0509
Trichomonas vaginalis set domain proteins, putative 0.0231 0.235 1
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0922 0.3924
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0102 0.0501
Schistosoma mansoni hypothetical protein 0.0015 0.0065 0.006
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0922 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0172 0.1313
Echinococcus multilocularis Niemann Pick C1 protein 0.0118 0.1153 0.1132
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Schistosoma mansoni kinase 0.0049 0.0421 0.0567
Loa Loa (eye worm) hypothetical protein 0.0023 0.0147 0.0134
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0102 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0102 0.0703
Brugia malayi MH2 domain containing protein 0.0116 0.1136 0.1084
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0102 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0407 0.1733
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0059 0.0045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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