Detailed information for compound 578835

Basic information

Technical information
  • TDR Targets ID: 578835
  • Name: N,N-bis(2-bromoethyl)-3-methyl-naphthalen-1-a mine
  • MW: 371.11 | Formula: C15H17Br2N
  • H donors: 0 H acceptors: 0 LogP: 5.18 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: BrCCN(c1cc(C)cc2c1cccc2)CCBr
  • InChi: 1S/C15H17Br2N/c1-12-10-13-4-2-3-5-14(13)15(11-12)18(8-6-16)9-7-17/h2-5,10-11H,6-9H2,1H3
  • InChiKey: YTSZNIWMCGRFHU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N,N-bis(2-bromoethyl)-3-methyl-1-naphthalenamine
  • bis(2-bromoethyl)-(3-methyl-1-naphthyl)amine
  • N,N-bis(2-bromoethyl)-3-methylnaphthalen-1-amine
  • 1-N,N-bis(beta-bromoethyl)amino-3-methylnaphthalene
  • 70974-82-2
  • 1-Naphthalenamine, N,N-bis(2-bromoethyl)-3-methyl-
  • WB 4325

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.0501
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.1091 0.5014
Echinococcus multilocularis dna polymerase kappa 0.0105 0.2156 0.2118
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0283 0.123
Echinococcus granulosus tachykinin peptides receptor 99D 0.0035 0.0535 0.0488
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0304 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Echinococcus granulosus hypothetical protein 0.0035 0.0535 0.0488
Schistosoma mansoni DNA polymerase eta 0.0103 0.2128 0.2128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Leishmania major DNA polymerase eta, putative 0.0103 0.2128 0.2882
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.1487 0.6988
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.1883 0.8848
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0194 0.07
Schistosoma mansoni amine GPCR 0.0035 0.0535 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0194 0.07
Echinococcus multilocularis orexin receptor type 2 0.0035 0.0535 0.0488
Brugia malayi hypothetical protein 0.0017 0.0112 0.0527
Loa Loa (eye worm) hypothetical protein 0.0022 0.0223 0.0838
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.1883 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0051 0.0002
Onchocerca volvulus 0.003 0.0412 0.219
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0535 0.0535
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0535 0.0488
Schistosoma mansoni alpha-1 adrenergic receptor 0.0035 0.0535 0.0535
Echinococcus granulosus CREB binding protein 0.0016 0.009 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.026 0.0314
Echinococcus multilocularis discoidin domain receptor 0.0022 0.0223 0.0175
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0535 0.0488
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0135 0.0087
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0135 0.0417
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0035 0.0535 0.0535
Brugia malayi follicle stimulating hormone receptor 0.0035 0.0535 0.2512
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0194 0.0194
Schistosoma mansoni hypothetical protein 0.0022 0.0223 0.0223
Schistosoma mansoni coup transcription factor 0.0021 0.0194 0.0194
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.3304 0.4498
Echinococcus granulosus serotonin receptor 0.0035 0.0535 0.0488
Trypanosoma brucei unspecified product 0.0052 0.0935 0.1242
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Brugia malayi CXXC zinc finger family protein 0.0059 0.1091 0.5128
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0283 0.123
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0535 0.0535
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0194 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0194 0.07
Brugia malayi Serotonin receptor 0.0035 0.0535 0.2512
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0035 0.0535 0.2337
Leishmania major DNA polymerase kappa, putative 0.0024 0.026 0.0314
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni neuropeptide receptor 0.0035 0.0535 0.0535
Schistosoma mansoni chromobox protein 0.0068 0.1312 0.1312
Onchocerca volvulus 0.0016 0.0084 0.0445
Echinococcus granulosus neuropeptide receptor 0.0035 0.0535 0.0488
Echinococcus granulosus neuropeptide receptor 0.0035 0.0535 0.0488
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.026 0.0314
Trichomonas vaginalis hypothetical protein 0.0022 0.0223 0.0947
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0223 0.656
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0535 0.0488
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0194 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0929 0.1234
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0194 0.0194
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0194 0.07
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.0501
Trichomonas vaginalis DNA polymerase eta, putative 0.0105 0.2156 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0035 0.0535 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Schistosoma mansoni amine GPCR 0.0035 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0283 0.123
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0194 0.0913
Brugia malayi GnHR receptor homolog 0.0035 0.0535 0.2512
Onchocerca volvulus 0.0035 0.0535 0.2839
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0129 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Brugia malayi Serotonin receptor 0.0035 0.0535 0.2512
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0304 0.0741
Echinococcus multilocularis dedicator of cytokinesis protein 0.0117 0.245 0.2413
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0194 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0283 0.123
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0535 0.0488
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0194 0.0146
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni hypothetical protein 0.0439 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0035 0.0535 0.2512
Leishmania major DNA polymerase eta, putative 0.0051 0.0901 0.1195
Schistosoma mansoni hypothetical protein 0.0035 0.0535 0.0535
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0535 0.0488
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0535 0.0488
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0194 0.0146
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0138 0.0549
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis sex peptide receptor 0.0035 0.0535 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0035 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0038 0.0607 0.2684
Echinococcus multilocularis allatostatin A receptor 0.0035 0.0535 0.0488
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0194 0.0146
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Loa Loa (eye worm) TK/ALK protein kinase 0.0017 0.0112 0.0305
Schistosoma mansoni neuropeptide receptor 0.0035 0.0535 0.0535
Onchocerca volvulus 0.0017 0.0112 0.0596
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0304 0.0375
Echinococcus granulosus 7tm_1 domain containing protein 0.0035 0.0535 0.0488
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0638 0.0834
Onchocerca volvulus Neuropeptide F receptor homolog 0.0035 0.0535 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Echinococcus granulosus g-protein coupled receptor 0.0035 0.0535 0.0488
Schistosoma mansoni hypothetical protein 0.0017 0.0112 0.0112
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.003 0.0412 0.1749
Mycobacterium tuberculosis Conserved hypothetical protein 0.0171 0.371 1
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0784 0.3575
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0304 0.0375
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.0901 0.1195
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0638 0.0834
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Brugia malayi neuropeptide F receptor 0.0035 0.0535 0.2512
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0194 0.0146
Schistosoma mansoni hypothetical protein 0.0016 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Mycobacterium ulcerans hypothetical protein 0.0024 0.026 0.0621
Schistosoma mansoni hypothetical protein 0.0035 0.0535 0.0535
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0675 0.3064
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0194 0.0146
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0035 0.0535 0.2337
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0304 0.0741
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0324 0.7307 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0194 0.0146
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0035 0.0535 0.0488
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0304 0.0375
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0194 0.07
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Echinococcus multilocularis CREB binding protein 0.0016 0.009 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Brugia malayi Muscle positioning protein 4 0.0016 0.0084 0.0393
Loa Loa (eye worm) TYRA-2 protein 0.0035 0.0535 0.2337
Echinococcus granulosus neuropeptide FF receptor 2 0.0035 0.0535 0.0488
Brugia malayi SEA domain containing protein 0.0016 0.0084 0.0393
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0035 0.0535 0.2337
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0535 0.0488
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0194 0.0146
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0035 0.0535 0.2512
Schistosoma mansoni hypothetical protein 0.0035 0.0535 0.0535
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0035 0.0535 0.0535
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.026 0.0314
Mycobacterium ulcerans hypothetical protein 0.0171 0.371 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Echinococcus granulosus discoidin domain receptor 0.0022 0.0223 0.0175
Echinococcus granulosus dro:myosuppressin receptor 0.0035 0.0535 0.0488
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Plasmodium vivax LCCL domain-containing protein 0.0022 0.0223 0.656
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0638 0.2889
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0283 0.123
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni CREB-binding protein 2 0.01 0.2045 0.2045
Loa Loa (eye worm) hypothetical protein 0.0017 0.0112 0.0305
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0022 0.0223 0.0947
Loa Loa (eye worm) hypothetical protein 0.0028 0.0362 0.1505
Schistosoma mansoni neuropeptide f receptor 76f 0.0035 0.0535 0.0535
Brugia malayi G-protein coupled receptor 0.0035 0.0535 0.2512
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0129 0.0265
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.1883 0.2545
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0139 0.2966 0.2931
Loa Loa (eye worm) hypothetical protein 0.004 0.0638 0.2832
Schistosoma mansoni cpg binding protein 0.0062 0.117 0.117
Brugia malayi Protein kinase domain containing protein 0.0022 0.0223 0.1047
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0638 0.2115
Brugia malayi TAZ zinc finger family protein 0.01 0.2045 0.9608
Brugia malayi larval opioid receptor 0.0035 0.0535 0.2512
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0194 0.07
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0194 0.0913
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Echinococcus granulosus CREB binding protein 0.01 0.2045 0.2006
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Schistosoma mansoni hypothetical protein 0.0035 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Echinococcus multilocularis cpg binding protein 0.0062 0.117 0.1127
Giardia lamblia DINP protein human, muc B family 0.0083 0.1653 0.8584
Onchocerca volvulus 0.0016 0.0084 0.0445
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0194 0.0146
Onchocerca volvulus 0.0022 0.0223 0.1183
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.026 0.0314
Schistosoma mansoni dock 0.0139 0.2966 0.2966
Echinococcus granulosus discoidin domain containing receptor 2 0.0022 0.0223 0.0175
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0535 0.0488
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.026 0.0314
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.026 0.0314
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0535 0.0535
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0024 0.026 0.0171
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0194 0.0913
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0535 0.0535
Schistosoma mansoni biogenic amine receptor 0.0035 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus granulosus g protein coupled receptor 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0016 0.0084 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0194 0.0913
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0304 0.0741
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.2156 0.5776
Schistosoma mansoni amine GPCR 0.0035 0.0535 0.0535
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni amine GPCR 0.0035 0.0535 0.0535
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0535 0.0488
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.2643 0.2643
Loa Loa (eye worm) CBP-B 0.0069 0.1331 0.6165
Schistosoma mansoni cpg binding protein 0.0059 0.1091 0.1091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0304 0.1226
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0535 0.2337
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0535 0.0488
Leishmania major DNA damage repair protein, putative 0.0024 0.026 0.0314
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0035 0.0535 0.0535
Brugia malayi G-protein coupled receptor 0.0035 0.0535 0.2512
Echinococcus granulosus g protein coupled receptor 0.0035 0.0535 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Trichomonas vaginalis chromobox protein, putative 0.0068 0.1312 0.6047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0929 0.4232
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0035 0.0535 0.0488
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0638 0.0592
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0194 0.0913
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0194 0.0146
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0194 0.0913
Echinococcus multilocularis G-protein coupled receptor, putative 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0103 0.2128 1
Echinococcus multilocularis fmrfamide receptor 0.0035 0.0535 0.0488
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0535 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0194 0.0913
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0194 0.0194
Schistosoma mansoni histamine h1 receptor 0.0035 0.0535 0.0535
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0035 0.0535 0.0488
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1883 0.2545
Schistosoma mansoni btb and poz domain-containing protein 0.0022 0.0223 0.0223
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Echinococcus multilocularis discoidin domain containing receptor 2 0.0022 0.0223 0.0175
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus granulosus G protein coupled receptor 139 0.0035 0.0535 0.0488
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0776 0.1023
Onchocerca volvulus 0.0035 0.0535 0.2839
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0035 0.0535 0.0488
Schistosoma mansoni opsin-like receptor 0.0035 0.0535 0.0535
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0035 0.0535 0.0488
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0035 0.0535 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0076 0.1487 0.1446
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0324 0.7307 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0194 0.0913
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0194 0.0913
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0076 0.1487 0.1446
Toxoplasma gondii hypothetical protein 0.0052 0.0933 0.3306
Echinococcus multilocularis serotonin receptor 0.0035 0.0535 0.0488
Echinococcus granulosus discoidin domain containing receptor 2 0.0022 0.0223 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.1101 0.147
Giardia lamblia Kinase, PLK 0.0093 0.1883 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0135 0.0087
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0035 0.0535 0.0488
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0223 0.656
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus granulosus g protein coupled receptor 0.0035 0.0535 0.0488
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0035 0.0535 0.0535
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0035 0.0535 0.0488
Leishmania major DNA polymerase kappa, putative 0.0083 0.1653 0.2229
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni adenoreceptor 0.0035 0.0535 0.0535
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0052 0.0929 0.1234
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni opsin-like receptor 0.0035 0.0535 0.0535
Brugia malayi nuclear hormone receptor 0.0021 0.0194 0.0913
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0035 0.0535 0.0488
Schistosoma mansoni discoidin domain receptor 0.0022 0.0223 0.0223
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.2371 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni neuropeptide receptor 0.0035 0.0535 0.0535
Onchocerca volvulus 0.0016 0.0084 0.0445
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0638 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0638 0.0638
Brugia malayi nuclear receptor NHR-88 0.0021 0.0194 0.0913
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0607 0.3222
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0035 0.0535 0.2512
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Echinococcus granulosus CREB binding protein 0.0062 0.1149 0.1106
Echinococcus granulosus dna polymerase eta 0.0103 0.2128 0.209
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0083 0.1653 0.2229
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0051 0.0002
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0638 0.0592
Echinococcus granulosus chromobox protein 1 0.0068 0.1312 0.127
Schistosoma mansoni kinase 0.0047 0.0813 0.0813
Loa Loa (eye worm) neuropeptide F receptor 0.0035 0.0535 0.2337
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0776 0.1023
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0153 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0076 0.1487 0.6917
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0153 0.0331
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0035 0.0535 0.0488
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Echinococcus multilocularis serotonin receptor 0.0035 0.0535 0.0488
Brugia malayi G protein-coupled receptor 0.0035 0.0535 0.2512
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0304 0.0741
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0035 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis CREB binding protein 0.0016 0.009 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0194 0.0913
Onchocerca volvulus 0.0016 0.0084 0.0445
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0194 0.07
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Brugia malayi Dopamine receptor protein 1 0.0035 0.0535 0.2512
Echinococcus multilocularis chromobox protein 1 0.0068 0.1312 0.127
Schistosoma mansoni growth hormone secretagogue receptor 0.0035 0.0535 0.0535
Schistosoma mansoni myosin xvIII 0.0035 0.0535 0.0535
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0129 0.0265
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0153 0.0331
Echinococcus granulosus fmrfamide receptor 0.0035 0.0535 0.0488
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0304 0.1427
Trypanosoma brucei unspecified product 0.0052 0.0935 0.1242
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0194 0.0146
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0194 0.0194
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0283 0.123
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0022 0.0223 0.0521
Onchocerca volvulus 0.0035 0.0535 0.2839
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0194 0.0913
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0138 0.0549
Schistosoma mansoni DNA polymerase IV / kappa 0.0024 0.026 0.026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Echinococcus multilocularis neuropeptide receptor A26 0.0035 0.0535 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0607 0.2744
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0638 0.0592
Echinococcus multilocularis nuclear receptor 2C2 associated protein 0.0022 0.0223 0.0175
Echinococcus granulosus alpha 1A adrenergic receptor 0.0035 0.0535 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0194 0.0146
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.2156 0.2921
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.0501
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0022 0.0223 0.0947
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Brugia malayi putative neuropeptide receptor 0.0035 0.0535 0.2512
Brugia malayi RE15519p 0.0035 0.0535 0.2512
Echinococcus multilocularis somatostatin receptor 0.0035 0.0535 0.0488
Onchocerca volvulus 0.0035 0.0535 0.2839
Brugia malayi sulfakinin receptor protein 0.0035 0.0535 0.2512
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Echinococcus granulosus somatostatin receptor 0.0035 0.0535 0.0488
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0154 0.3304 0.4498
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0304 0.1427
Brugia malayi steroid hormone receptor 0.0021 0.0194 0.0913
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0051 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.1009 0.1345
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0194 0.0194
Echinococcus multilocularis g-protein coupled receptor 0.0035 0.0535 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0083 0.1653 0.2229
Trypanosoma brucei polo-like protein kinase 0.0093 0.1883 0.2545
Echinococcus multilocularis neuropeptides capa receptor 0.0035 0.0535 0.0488
Schistosoma mansoni amine GPCR 0.0035 0.0535 0.0535
Brugia malayi ecdysteroid receptor 0.0021 0.0194 0.0913
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0194 0.1031
Echinococcus multilocularis chromobox protein 1 0.0068 0.1312 0.127
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Onchocerca volvulus 0.0035 0.0535 0.2839
Trypanosoma brucei DNA polymerase IV, putative 0.0105 0.2156 0.2921
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0283 0.123
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0638 0.0638
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0194 0.0194
Brugia malayi Heterochromatin protein 1 0.0068 0.1312 0.6165
Schistosoma mansoni terminal deoxycytidyl transferase 0.0076 0.1487 0.1487
Brugia malayi Melatonin receptor type 1A 0.0035 0.0535 0.2512
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0194 0.0913
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0638 0.2996
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0194 0.0194
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0535 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0784 0.3575
Echinococcus granulosus CREB binding protein 0.0016 0.009 0.0042
Trypanosoma brucei chrX additional, unordered contigs 0.0024 0.026 0.0314
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0535 0.0488
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0675 0.3585
Onchocerca volvulus 0.0035 0.0535 0.2839
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0194 0.0146
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.0501
Schistosoma mansoni biogenic amine receptor 0.0035 0.0535 0.0535
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Loa Loa (eye worm) melatonin receptor type 1A 0.0035 0.0535 0.2337
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0304 0.0741
Loa Loa (eye worm) hypothetical protein 0.0017 0.0112 0.0305
Trypanosoma brucei unspecified product 0.0097 0.199 0.2693
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0194 0.0913
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0638 0.0834
Loa Loa (eye worm) hypothetical protein 0.0047 0.0805 0.3635
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.1883 0.2545
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Echinococcus granulosus discoidin domain containing receptor 2 0.0022 0.0223 0.0175
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Trypanosoma cruzi DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.1883 0.1883
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0022 0.0223 0.0947
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0105 0.2156 0.2921
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Plasmodium vivax LCCL domain-containing protein 0.0022 0.0223 0.656
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0344 0.1514
Brugia malayi ORL1-like opioid receptor 0.0035 0.0535 0.2512
Leishmania major mitochondrial DNA polymerase beta 0.0324 0.7307 1
Schistosoma mansoni biogenic amine receptor 0.0035 0.0535 0.0535
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0129 0.0265
Echinococcus multilocularis G protein coupled receptor 139 0.0035 0.0535 0.0488
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0194 0.0913
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.1883 0.8721
Onchocerca volvulus 0.0022 0.0223 0.1183
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0035 0.0535 0.2337
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.01 0.2045 0.2045
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Onchocerca volvulus 0.0017 0.0112 0.0596
Onchocerca volvulus 0.0025 0.0304 0.1613
Trypanosoma cruzi DNA polymerase eta, putative 0.0103 0.2128 0.2882
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Entamoeba histolytica deoxycytidyl transferase, putative 0.0076 0.1487 0.7493
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni opsin-like receptor 0.0035 0.0535 0.0535
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0638 0.0592
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0675 0.3064
Echinococcus multilocularis neuropeptide FF receptor 2 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Echinococcus multilocularis neuropeptide Y receptor 0.0035 0.0535 0.0488
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0083 0.1653 0.4409
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0535 0.0535
Schistosoma mansoni hypothetical protein 0.0017 0.0112 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0194 0.07
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0638 0.0592
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0535 0.0488
Trypanosoma brucei DNA damage repair protein, putative 0.0024 0.026 0.0314
Loa Loa (eye worm) hypothetical protein 0.0025 0.0304 0.1226
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.1101 0.147
Onchocerca volvulus 0.0035 0.0535 0.2839
Trypanosoma cruzi DNA damage repair protein, putative 0.0024 0.026 0.0314
Echinococcus granulosus neuropeptide s receptor 0.0035 0.0535 0.0488
Echinococcus granulosus cpg binding protein 0.0062 0.117 0.1127
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0194 0.0913
Echinococcus granulosus neuropeptides capa receptor 0.0035 0.0535 0.0488
Mycobacterium tuberculosis Conserved hypothetical protein 0.0076 0.1487 0.3958
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0019 0.0153 0.0501
Onchocerca volvulus 0.0035 0.0535 0.2839
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.1883 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0283 0.123
Loa Loa (eye worm) G-protein coupled receptor 0.0035 0.0535 0.2337
Echinococcus multilocularis dnaJ subfamily B 0.0439 1 1
Brugia malayi chromobox protein homolog 3 0.0038 0.0607 0.2851
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Onchocerca volvulus 0.0016 0.0084 0.0445
Echinococcus granulosus allatostatin A receptor 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Schistosoma mansoni septate junction protein 0.0022 0.0223 0.0223
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.1883 0.1843
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0638 0.0834
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0115 0.0442
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis neuropeptide s receptor 0.0035 0.0535 0.0488
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0035 0.0535 0.0535
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0304 0.0741
Brugia malayi Dopamine receptor 0.0035 0.0535 0.2512
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Plasmodium vivax DNA repair protein REV1, putative 0.0024 0.026 1
Brugia malayi neuropeptide F receptor 0.0035 0.0535 0.2512
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0035 0.0535 0.2337
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0031 0.0426 0.0944
Echinococcus granulosus Coagulation factor 5 8 type C terminal 0.0139 0.2966 0.2931
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0194 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0638 0.2889
Brugia malayi G protein-coupled receptor F59B2.13 0.0035 0.0535 0.2512
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.1312 0.6075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0035 0.0535 0.2512
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Brugia malayi hypothetical protein 0.0035 0.0535 0.2512
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0105 0.2156 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0194 0.0913
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.013 0.061
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0304 0.0741
Echinococcus multilocularis g protein coupled receptor 0.0035 0.0535 0.0488
Echinococcus multilocularis discoidin domain containing receptor 2 0.0022 0.0223 0.0175
Brugia malayi AKH receptor 0.0035 0.0535 0.2512
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0035 0.0535 0.0488
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0035 0.0535 0.0488
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0776 0.1023
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.0901 0.3156
Schistosoma mansoni neuropeptide F-like receptor 0.0035 0.0535 0.0535
Schistosoma mansoni discoidin domain receptor 0.0022 0.0223 0.0223
Brugia malayi Protein kinase domain containing protein 0.0017 0.0112 0.0527
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.3304 0.4498
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0035 0.0535 0.2512
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0194 0.0194
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0035 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0304 0.0741
Echinococcus multilocularis CREB binding protein 0.0068 0.131 0.1268
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0304 0.0741
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus granulosus dna polymerase kappa 0.0105 0.2156 0.2118
Brugia malayi CHD4 protein 0.0015 0.0049 0.0229
Onchocerca volvulus 0.0035 0.0535 0.2839
Brugia malayi putative neuropeptide receptor NPR1 0.0035 0.0535 0.2512
Echinococcus granulosus neuropeptide Y receptor 0.0035 0.0535 0.0488
Mycobacterium ulcerans DNA polymerase IV 0.0105 0.2156 0.5776
Echinococcus multilocularis dna polymerase eta 0.0103 0.2128 0.209
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0776 0.1023
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.1101 0.147
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0304 0.1427
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis dro:myosuppressin receptor 0.0035 0.0535 0.0488
Echinococcus granulosus neuropeptide receptor A26 0.0035 0.0535 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Brugia malayi Dopamine receptor protein 2 0.0035 0.0535 0.2512
Brugia malayi polk-prov protein 0.0052 0.0929 0.4364
Echinococcus granulosus chromobox protein 1 0.0068 0.1312 0.127
Echinococcus multilocularis neuropeptide receptor 0.0035 0.0535 0.0488
Echinococcus granulosus 7TM GPCR rhodopsin 0.0035 0.0535 0.0488
Trypanosoma brucei DNA polymerase eta, putative 0.0103 0.2128 0.2882
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0035 0.0535 0.2839
Onchocerca volvulus 0.0059 0.1091 0.5796
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0076 0.1487 0.1487
Trypanosoma brucei DNA polymerase IV, putative 0.0097 0.199 0.2693
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0194 0.0194
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Echinococcus multilocularis MAM 0.0017 0.0112 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0194 0.0194
Loa Loa (eye worm) DOMON domain-containing protein 0.0016 0.0084 0.0168
Trichomonas vaginalis chromobox protein, putative 0.0068 0.1312 0.6047
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0049 0.0049
Echinococcus granulosus tm gpcr rhodopsin 0.0035 0.0535 0.0488
Onchocerca volvulus 0.0021 0.0194 0.1031
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0223 0.0947
Onchocerca volvulus 0.0035 0.0535 0.2839
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0194 0.0146
Echinococcus multilocularis discoidin domain containing receptor 2 0.0022 0.0223 0.0175
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Onchocerca volvulus 0.0035 0.0535 0.2839
Echinococcus multilocularis rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Schistosoma mansoni cpg binding protein 0.0062 0.117 0.117
Echinococcus multilocularis CREB binding protein 0.0016 0.009 0.0042
Schistosoma mansoni biogenic amine (5HT) receptor 0.0035 0.0535 0.0535
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.1883 0.1843
Echinococcus granulosus peptide allatostatin:somatostatin 0.0035 0.0535 0.0488
Loa Loa (eye worm) hypothetical protein 0.0035 0.0535 0.2337
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0194 0.1031
Brugia malayi ImpB/MucB/SamB family protein 0.0103 0.2128 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0194 0.0146
Echinococcus granulosus biogenic amine 5HT receptor 0.0035 0.0535 0.0488
Echinococcus granulosus orexin receptor type 2 0.0035 0.0535 0.0488
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0035 0.0535 0.0535
Mycobacterium ulcerans hypothetical protein 0.0025 0.0304 0.0741
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0638 0.2889
Loa Loa (eye worm) hypothetical protein 0.0016 0.0084 0.0168
Plasmodium falciparum DNA repair protein REV1, putative 0.0024 0.026 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0223 0.0838
Loa Loa (eye worm) hypothetical protein 0.0025 0.0304 0.1226
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0344 0.1514
Loa Loa (eye worm) hypothetical protein 0.0021 0.0194 0.07
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0051 0.0051
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0051 0.0002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0035 0.0535 0.2512
Echinococcus granulosus rhodopsin orphan GPCR 0.0035 0.0535 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0607 0.2744
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0324 0.7307 1
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.1883 0.8821
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0638 0.2329
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0035 0.0535 0.0535
Schistosoma mansoni chromobox protein 0.0068 0.1312 0.1312
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0194 0.1031
Schistosoma mansoni neuropeptide receptor 0.0035 0.0535 0.0535
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0304 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0112 0.0305
Echinococcus granulosus sex peptide receptor 0.0035 0.0535 0.0488
Echinococcus granulosus MAM 0.0017 0.0112 0.0064
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0035 0.0535 0.0535

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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