Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0211 | 0.055 | 0.0953 |
Echinococcus granulosus | lamin | 0.0141 | 0.0308 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0047 | 0.0079 |
Brugia malayi | MH1 domain containing protein | 0.0065 | 0.0045 | 0.0075 |
Loa Loa (eye worm) | RNA binding protein | 0.0919 | 0.3002 | 0.5221 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0162 | 0.038 | 0.398 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0319 | 0.0924 | 0.2803 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0273 | 0.0766 | 1 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0217 | 0.0573 | 0.1589 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0919 | 0.3002 | 0.5221 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0426 | 0.1296 | 0.2253 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.0299 | 0.0518 |
Echinococcus multilocularis | glutamate synthase | 0.0085 | 0.0114 | 0.0151 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0273 | 0.0766 | 0.0766 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0108 | 0.0195 | 0.0258 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0075 | 0.0082 | 0.014 |
Leishmania major | trypanothione reductase | 0.092 | 0.3005 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Loa Loa (eye worm) | glutathione reductase | 0.092 | 0.3005 | 0.5226 |
Loa Loa (eye worm) | TAR-binding protein | 0.0919 | 0.3002 | 0.5221 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0092 | 0.0138 | 0.0183 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0085 | 0.0114 | 0.0151 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0273 | 0.0766 | 0.2255 |
Echinococcus granulosus | lamin dm0 | 0.0141 | 0.0308 | 0.0411 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0135 | 0.0288 | 0.0498 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0085 | 0.0114 | 0.0314 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0319 | 0.0924 | 0.2803 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0234 | 0.0632 | 0.1096 |
Brugia malayi | RNA binding protein | 0.0919 | 0.3002 | 0.5221 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0117 | 0.0225 | 0.0389 |
Echinococcus multilocularis | tumor protein p63 | 0.1743 | 0.5853 | 0.784 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.2333 | 0.7893 | 1 |
Schistosoma mansoni | smad | 0.0117 | 0.0225 | 0.0225 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Echinococcus multilocularis | GPCR, family 2 | 0.0135 | 0.0288 | 0.0384 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0273 | 0.0766 | 0.2255 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.0631 | 0.0664 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Plasmodium falciparum | glutathione reductase | 0.092 | 0.3005 | 1 |
Toxoplasma gondii | selenide, water dikinase | 0.0085 | 0.0114 | 0.0314 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Plasmodium falciparum | glutathione reductase | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0135 | 0.0288 | 0.0384 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0085 | 0.0114 | 0.0151 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0319 | 0.0924 | 0.1606 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0068 | 0.0056 | 0.0073 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0319 | 0.0924 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0426 | 0.1296 | 0.2253 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2209 | 0.7464 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Echinococcus granulosus | Smad4 | 0.0117 | 0.0225 | 0.0299 |
Loa Loa (eye worm) | intermediate filament protein | 0.0141 | 0.0308 | 0.0533 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0135 | 0.0288 | 0.0498 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0085 | 0.0114 | 0.0151 |
Plasmodium falciparum | thioredoxin reductase | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0163 | 0.0386 | 0.4042 |
Schistosoma mansoni | smad1 5 8 and | 0.0117 | 0.0225 | 0.0225 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.0075 | 0.0602 |
Echinococcus granulosus | microtubule associated protein 2 | 0.2209 | 0.7464 | 1 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0085 | 0.0114 | 0.0151 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0085 | 0.0114 | 0.0195 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.2099 | 0.7083 | 0.8958 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0085 | 0.0114 | 0.1037 |
Brugia malayi | Thioredoxin reductase | 0.092 | 0.3005 | 0.5226 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0195 | 0.0195 |
Schistosoma mansoni | lamin | 0.0141 | 0.0308 | 0.0308 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Schistosoma mansoni | glutamate synthase | 0.0085 | 0.0114 | 0.0114 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0919 | 0.3002 | 0.5221 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0135 | 0.0288 | 0.0498 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0273 | 0.0766 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0014 | 0.0021 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.1713 | 0.5748 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0117 | 0.0225 | 0.0225 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Schistosoma mansoni | smad | 0.0052 | 0.0002 | 0.0002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0085 | 0.0114 | 0.0314 |
Onchocerca volvulus | 0.024 | 0.065 | 0.9234 | |
Loa Loa (eye worm) | Smad1 | 0.0117 | 0.0225 | 0.0389 |
Schistosoma mansoni | smad1 5 8 and | 0.0117 | 0.0225 | 0.0225 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0085 | 0.0114 | 0.0114 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.2333 | 0.7893 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0273 | 0.0766 | 0.8248 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0288 | 0.0498 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0273 | 0.0766 | 0.2255 |
Echinococcus granulosus | tumor protein p63 | 0.1743 | 0.5853 | 0.784 |
Echinococcus multilocularis | tar DNA binding protein | 0.0919 | 0.3002 | 0.402 |
Brugia malayi | intermediate filament protein | 0.0141 | 0.0308 | 0.0533 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0273 | 0.0766 | 0.8248 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0217 | 0.0573 | 0.1589 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0273 | 0.0766 | 0.1024 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0319 | 0.0924 | 1 |
Schistosoma mansoni | Smad4 | 0.0052 | 0.0002 | 0.0002 |
Brugia malayi | MH1 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0319 | 0.0924 | 1 |
Schistosoma mansoni | glutamate synthase | 0.0085 | 0.0114 | 0.0114 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0163 | 0.0386 | 0.4042 |
Echinococcus granulosus | glutamate synthase | 0.0085 | 0.0114 | 0.0151 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0255 | 0.0704 | 0.0704 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Plasmodium vivax | glutathione reductase, putative | 0.092 | 0.3005 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Onchocerca volvulus | 0.0141 | 0.0308 | 0.4362 | |
Schistosoma mansoni | Smad4 | 0.0052 | 0.0002 | 0.0002 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Echinococcus multilocularis | musashi | 0.0141 | 0.0308 | 0.0411 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.0924 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0273 | 0.0766 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.3432 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0056 | 0.0095 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0085 | 0.0114 | 0.0314 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0085 | 0.0114 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.0704 | 0.1222 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0273 | 0.0766 | 0.8248 |
Echinococcus granulosus | smad | 0.0117 | 0.0225 | 0.0299 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.2333 | 0.7893 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0135 | 0.0288 | 0.0384 |
Brugia malayi | MH1 domain containing protein | 0.0065 | 0.0045 | 0.0075 |
Giardia lamblia | GTOR | 0.0273 | 0.0766 | 0.8045 |
Brugia malayi | glutamate synthase | 0.0085 | 0.0114 | 0.0195 |
Onchocerca volvulus | 0.0085 | 0.0114 | 0.1599 | |
Toxoplasma gondii | thioredoxin reductase | 0.092 | 0.3005 | 1 |
Schistosoma mansoni | lamin | 0.0141 | 0.0308 | 0.0308 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0327 | 0.0566 |
Echinococcus multilocularis | lamin dm0 | 0.0141 | 0.0308 | 0.0411 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.092 | 0.3005 | 0.3716 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.1236 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0085 | 0.0114 | 0.1037 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0319 | 0.0924 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.092 | 0.3005 | 0.5226 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0047 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0163 | 0.0386 | 0.4042 |
Schistosoma mansoni | smad1 5 8 and | 0.0117 | 0.0225 | 0.0225 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0319 | 0.0924 | 0.3029 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0045 | 0.0075 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.1236 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0319 | 0.0924 | 1 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0273 | 0.0766 | 0.2255 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0108 | 0.0195 | 0.0195 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Onchocerca volvulus | 0.0141 | 0.0308 | 0.4362 | |
Brugia malayi | TAR-binding protein | 0.0919 | 0.3002 | 0.5221 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0135 | 0.0288 | 0.0384 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0183 | 0.0455 | 0.4807 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.3432 |
Mycobacterium tuberculosis | Probable reductase | 0.2099 | 0.7083 | 0.8958 |
Onchocerca volvulus | 0.0255 | 0.0704 | 1 | |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0117 | 0.0225 | 0.0299 |
Plasmodium falciparum | thioredoxin reductase | 0.092 | 0.3005 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0129 | 0.0268 | 0.0533 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0085 | 0.0114 | 0.0195 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0273 | 0.0766 | 0.2255 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0117 | 0.0225 | 0.0299 |
Schistosoma mansoni | glutamate synthase | 0.0085 | 0.0114 | 0.0114 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.092 | 0.3005 | 1 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0217 | 0.0573 | 0.1589 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0327 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0426 | 0.1296 | 0.2253 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Trichomonas vaginalis | set domain proteins, putative | 0.024 | 0.065 | 0.6968 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.3432 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus multilocularis | lamin | 0.0141 | 0.0308 | 0.0411 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0092 | 0.0138 | 0.0237 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | nuclear factor I | 0.0065 | 0.0045 | 0.0075 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0234 | 0.0632 | 0.1096 |
Schistosoma mansoni | sulfide quinone reductase | 0.0085 | 0.0114 | 0.0114 |
Schistosoma mansoni | sulfide quinone reductase | 0.0085 | 0.0114 | 0.0114 |
Schistosoma mansoni | intermediate filament proteins | 0.0141 | 0.0308 | 0.0308 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Echinococcus multilocularis | smad | 0.0117 | 0.0225 | 0.0299 |
Brugia malayi | hypothetical protein | 0.0108 | 0.0195 | 0.0336 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0114 | 0.0114 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0319 | 0.0924 | 0.2803 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0319 | 0.0924 | 0.2803 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0319 | 0.0924 | 0.2803 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0319 | 0.0924 | 0.2803 |
Plasmodium vivax | thioredoxin reductase, putative | 0.092 | 0.3005 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0117 | 0.0225 | 0.0299 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0319 | 0.0924 | 0.2803 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0092 | 0.0138 | 0.0138 |
Brugia malayi | Pre-SET motif family protein | 0.0211 | 0.055 | 0.0953 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0177 | 0.0435 | 0.4582 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.002 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.2099 | 0.7083 | 0.8958 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0092 | 0.0138 | 0.0237 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0085 | 0.0114 | 0.0314 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0928 | 0.3031 | 0.406 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.2099 | 0.7083 | 0.8958 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0085 | 0.0114 | 0.0195 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.2333 | 0.7893 | 1 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0085 | 0.0114 | 0.0151 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0319 | 0.0924 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0114 | 0.0195 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0068 | 0.0056 | 0.0073 |
Brugia malayi | Smad1 | 0.0117 | 0.0225 | 0.0389 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Onchocerca volvulus | 0.0146 | 0.0327 | 0.4632 | |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Treponema pallidum | NADH oxidase | 0.0319 | 0.0924 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.2099 | 0.7083 | 0.8958 |
Echinococcus granulosus | tar DNA binding protein | 0.0919 | 0.3002 | 0.402 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0319 | 0.0924 | 1 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0085 | 0.0114 | 0.0195 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0117 | 0.0225 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.083 | 0.1441 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0426 | 0.1296 | 0.2253 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0141 | 0.0308 | 0.0533 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2209 | 0.7464 | 0.7464 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Echinococcus multilocularis | Smad4 | 0.0117 | 0.0225 | 0.0299 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Schistosoma mansoni | Smad4 | 0.0117 | 0.0225 | 0.0225 |
Trypanosoma brucei | trypanothione reductase | 0.092 | 0.3005 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0141 | 0.0308 | 0.0411 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0273 | 0.0766 | 0.1024 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0273 | 0.0766 | 0.133 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0319 | 0.0924 | 0.1042 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0092 | 0.0138 | 0.0183 |
Echinococcus granulosus | GPCR family 2 | 0.0135 | 0.0288 | 0.0384 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0085 | 0.0114 | 0.0195 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0075 | 0.0082 | 0.014 |
Brugia malayi | MH2 domain containing protein | 0.1713 | 0.5748 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0233 | 0.0628 | 0.672 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Schistosoma mansoni | hypothetical protein | 0.0291 | 0.083 | 0.083 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0108 | 0.0195 | 0.0258 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.2099 | 0.7083 | 0.8958 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0162 | 0.038 | 0.398 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.2803 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.2099 | 0.7083 | 0.8958 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0141 | 0.0308 | 0.0533 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0203 | 0.0524 | 0.1687 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0113 | 0.0214 | 0.0344 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0273 | 0.0766 | 0.133 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0928 | 0.3031 | 0.406 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0319 | 0.0924 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.0225 | 0.0389 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.2803 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0291 | 0.083 | 0.1441 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0135 | 0.0288 | 0.0384 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0308 | 0.0533 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0085 | 0.0114 | 0.0314 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0319 | 0.0924 | 0.3029 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.1713 | 0.5748 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Brugia malayi | glutathione reductase | 0.092 | 0.3005 | 0.5226 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.