Detailed information for compound 651429

Basic information

Technical information
  • TDR Targets ID: 651429
  • Name: N-(9,10-dioxoanthracen-1-yl)-4-methoxybenzami de
  • MW: 357.359 | Formula: C22H15NO4
  • H donors: 1 H acceptors: 3 LogP: 4.23 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)C(=O)Nc1cccc2c1C(=O)c1ccccc1C2=O
  • InChi: 1S/C22H15NO4/c1-27-14-11-9-13(10-12-14)22(26)23-18-8-4-7-17-19(18)21(25)16-6-3-2-5-15(16)20(17)24/h2-12H,1H3,(H,23,26)
  • InChiKey: VGSMPPZALKNNJT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(9,10-dioxo-1-anthryl)-4-methoxy-benzamide
  • N-(9,10-dioxo-1-anthryl)-4-methoxybenzamide
  • N-(9,10-diketo-1-anthryl)-4-methoxy-benzamide
  • N-(9,10-dioxoanthracen-1-yl)-4-methoxy-benzamide
  • EU-0000932
  • ZINC03898689

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0104 0.1843 0.14
Mycobacterium leprae conserved hypothetical protein 0.0073 0.1126 0.052
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0427 1
Echinococcus granulosus importin subunit beta 1 0.0034 0.0243 0.0318
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.1126 0.0644
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.007 0.1072 0.3506
Giardia lamblia Alanyl dipeptidyl peptidase 0.0029 0.0144 0.266
Giardia lamblia Alanyl dipeptidyl peptidase 0.0029 0.0144 0.266
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0511 0.0669
Trypanosoma cruzi prolyl endopeptidase 0.0155 0.2981 1
Mycobacterium tuberculosis Probable peptidase 0.007 0.1072 0.0587
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1126 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.1126 0.0644
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.007 0.1072 0.0587
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0155 0.2981 0.3905
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0041 0.0054
Mycobacterium tuberculosis Conserved protein 0.0073 0.1126 0.0644
Entamoeba histolytica hypothetical protein 0.0027 0.0099 0.1483
Mycobacterium ulcerans lipase LipD 0.0073 0.1126 1
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0144 0.0349
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0515 0.0624
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0061 0.0856 0.1121
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0689 0.0902
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0243 0.0686
Loa Loa (eye worm) prolyl oligopeptidase 0.0029 0.0144 0.0135
Loa Loa (eye worm) hypothetical protein 0.0061 0.0856 0.1073
Plasmodium vivax hypothetical protein, conserved 0.0073 0.1126 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0144 0.0135
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.1126 0.1475
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0077 0.1222 0.4015
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0077 0.1222 0.4015
Echinococcus multilocularis histone acetyltransferase MYST2 0.0061 0.0856 0.1121
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.0689 0.0902
Echinococcus multilocularis geminin 0.0334 0.703 0.9208
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0041 0.0054
Loa Loa (eye worm) hypothetical protein 0.0048 0.0557 0.0679
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.0689 0.0902
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0513 0.1606
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0077 0.1222 0.4015
Schistosoma mansoni hypothetical protein 0.036 0.7635 1
Brugia malayi hypothetical protein 0.0048 0.0557 0.1009
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1126 0.1475
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0029 0.0144 0.266
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.2107 0.1678
Onchocerca volvulus Prolyl endopeptidase homolog 0.0155 0.2981 0.6911
Echinococcus multilocularis prolyl endopeptidase 0.0155 0.2981 0.3905
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0029 0.0144 0.0946
Mycobacterium tuberculosis Probable dehydrogenase 0.0104 0.1843 0.14
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0689 0.1267
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0029 0.0144 0.0188
Toxoplasma gondii ABC1 family protein 0.0073 0.1126 0.3689
Mycobacterium tuberculosis Probable reductase 0.0104 0.1843 0.14
Trypanosoma brucei prolyl endopeptidase 0.0155 0.2981 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1126 1
Echinococcus granulosus acylamino acid releasing enzyme 0.0029 0.0144 0.0188
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.02 0.4006 0.5247
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0641 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0513 0.4353
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0104 0.1843 0.7451
Brugia malayi hypothetical protein 0.0033 0.0229 0.0367
Loa Loa (eye worm) hypothetical protein 0.0053 0.0689 0.0853
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0099 0.0528
Loa Loa (eye worm) hypothetical protein 0.0155 0.2981 0.3872
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0251 0.5152 0.6731
Loa Loa (eye worm) prolyl oligopeptidase 0.02 0.4006 0.5221
Plasmodium falciparum thioredoxin reductase 0.0046 0.0515 0.791
Loa Loa (eye worm) acetyltransferase 0.0155 0.2996 0.3891
Loa Loa (eye worm) hypothetical protein 0.0073 0.1126 0.1428
Plasmodium falciparum glutathione reductase 0.0046 0.0515 0.791
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.0689 0.0902
Onchocerca volvulus 0.0073 0.1126 0.1318
Schistosoma mansoni eyes absent homolog 0.0085 0.141 0.1847
Brugia malayi prolyl oligopeptidase family protein 0.0029 0.0144 0.0201
Brugia malayi Importin beta-1 subunit 0.0034 0.0243 0.0395
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0061 0.0856 0.1594
Brugia malayi Thioredoxin reductase 0.0046 0.0515 0.0928
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.007 0.1072 0.3506
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0513 0.1606
Entamoeba histolytica prolyl oligopeptidase family protein 0.0029 0.0144 0.266
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0511 0.0669
Trypanosoma brucei trypanothione reductase 0.0046 0.0515 0.1613
Toxoplasma gondii hypothetical protein 0.0029 0.0144 0.0349
Loa Loa (eye worm) hypothetical protein 0.0085 0.141 0.1803
Loa Loa (eye worm) hypothetical protein 0.0037 0.0306 0.0349
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.2996 0.3924
Onchocerca volvulus 0.0073 0.1126 0.1318
Leishmania major importin beta-1 subunit, putative 0.0027 0.0099 0.0195
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0243 0.0686
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0243 0.0686
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.0689 0.0902
Trypanosoma cruzi oligopeptidase b 0.007 0.1072 0.3506
Schistosoma mansoni hypothetical protein 0.0329 0.6921 0.9065
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.1126 0.0644
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0511 0.0618
Entamoeba histolytica prolyl oligopeptidase family protein 0.0029 0.0144 0.266
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.02 0.4006 1
Echinococcus multilocularis snurportin 1 0.036 0.7635 1
Echinococcus granulosus geminin 0.0334 0.703 0.9208
Loa Loa (eye worm) glutathione reductase 0.0046 0.0515 0.0624
Echinococcus granulosus snurportin 1 0.036 0.7635 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0144 0.0135
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0077 0.1222 0.4015
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0029 0.0144 0.0349
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.007 0.1072 0.3506
Brugia malayi hypothetical protein 0.0051 0.0641 0.1173
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0511 0.0669
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0077 0.1222 0.4015
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1126 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0511 0.0669
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.2996 0.3924
Loa Loa (eye worm) hypothetical protein 0.0073 0.1126 0.1428
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.2898 0.3795
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0155 0.2981 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.036 0.7635 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0104 0.1843 0.14
Schistosoma mansoni hypothetical protein 0.0334 0.703 0.9208
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0104 0.1843 0.14
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0125 0.2316 0.1899
Trichomonas vaginalis esterase, putative 0.0073 0.1126 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0427 0.6439
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1126 0.1475
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0099 0.0528
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.1126 0.2122
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.1126 0.1475
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0641 1
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0029 0.0144 0.0946
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0515 0.4371
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0511 0.0669
Echinococcus granulosus Dipeptidyl peptidase 9 0.0077 0.1222 0.16
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.0689 0.0902
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.1126 0.0644
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0144 0.0349
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0306 0.0518
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0511 0.0669
Schistosoma mansoni ran 0.0025 0.0041 0.0054
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.1126 0.1428
Plasmodium vivax importin-beta 2, putative 0.0034 0.0243 0.186
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0515 0.0675
Loa Loa (eye worm) hypothetical protein 0.0073 0.1126 0.1428
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0215 0.4334 0.5677
Loa Loa (eye worm) beta-lactamase 0.0073 0.1126 0.1428
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0077 0.1222 0.16
Echinococcus granulosus prolyl endopeptidase 0.0155 0.2981 0.3905
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.007 0.1072 0.3506
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0029 0.0144 0.0188
Brugia malayi prolyl oligopeptidase family protein 0.0155 0.2981 0.5752
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.02 0.4006 0.5247
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.1126 0.3689
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.1126 0.0644
Loa Loa (eye worm) MBCTL1 0.0061 0.0856 0.1073
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0427 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0099 0.0195
Brugia malayi glutathione reductase 0.0046 0.0515 0.0928
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0061 0.0856 0.1121
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0215 0.4334 0.5677
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0513 0.4353
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0104 0.1843 0.14
Mycobacterium tuberculosis Conserved protein 0.0073 0.1126 0.0644
Leishmania major oligopeptidase b 0.007 0.1072 0.3506
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1126 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0641 0.2039
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1126 0.3689
Loa Loa (eye worm) hypothetical protein 0.0053 0.0689 0.0853
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.2107 0.1678
Echinococcus granulosus histone acetyltransferase MYST2 0.0061 0.0856 0.1121
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1126 1
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0077 0.1222 0.16
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0144 0.0946
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0155 0.2981 0.3905
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.1126 0.0644
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0641 0.2039
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0515 0.1613
Trypanosoma brucei prolyl oligopeptidase, putative 0.007 0.1072 0.3506
Plasmodium falciparum importin beta, putative 0.0034 0.0243 0.3366
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0513 0.4353
Brugia malayi beta-lactamase 0.0073 0.1126 0.2122
Brugia malayi follicle stimulating hormone receptor 0.0251 0.5152 1
Brugia malayi mbt repeat family protein 0.0053 0.0689 0.1267
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0641 0.5526
Trypanosoma cruzi oligopeptidase b 0.007 0.1072 0.3506
Mycobacterium leprae Probable lipase LipE 0.0073 0.1126 0.052
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.1126 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0641 0.0789
Loa Loa (eye worm) hypothetical protein 0.0073 0.1126 0.1428
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0515 0.0675
Schistosoma mansoni hypothetical protein 0.0037 0.0306 0.0401
Onchocerca volvulus 0.0073 0.1126 0.1318
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.2107 1
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.0689 0.0902
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0029 0.0144 0.266
Loa Loa (eye worm) hypothetical protein 0.0073 0.1126 0.1428
Entamoeba histolytica prolyl oligopeptidase family protein 0.0029 0.0144 0.266
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0641 0.2039
Toxoplasma gondii prolyl endopeptidase 0.0155 0.2981 1
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1126 0.3689
Brugia malayi mbt repeat family protein 0.0053 0.0689 0.1267
Schistosoma mansoni importin beta-1 0.0034 0.0243 0.0318
Brugia malayi RNA, U transporter 1 0.0096 0.1652 0.315
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0077 0.1222 0.4015
Mycobacterium ulcerans beta-lactamase 0.0073 0.1126 1
Schistosoma mansoni ran 0.0025 0.0041 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0144 0.0946
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0099 0.0528
Loa Loa (eye worm) hypothetical protein 0.0034 0.0243 0.0266
Mycobacterium tuberculosis Conserved protein 0.0073 0.1126 0.0644
Brugia malayi prolyl oligopeptidase family protein 0.02 0.4006 0.7757
Schistosoma mansoni hypothetical protein 0.0334 0.703 0.9208
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0029 0.0144 0.0349
Brugia malayi beta-lactamase family protein 0.0073 0.1126 0.2122
Entamoeba histolytica hypothetical protein, conserved 0.0029 0.0144 0.266
Brugia malayi prolyl oligopeptidase family protein 0.0029 0.0144 0.0201
Leishmania major hypothetical protein, conserved 0.0051 0.0641 0.2039
Loa Loa (eye worm) hypothetical protein 0.0085 0.141 0.1803
Plasmodium vivax glutathione reductase, putative 0.0046 0.0515 0.4371
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.02 0.4006 0.5247
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.0689 0.0853
Brugia malayi hypothetical protein 0.0085 0.141 0.2679
Trypanosoma brucei oligopeptidase b 0.007 0.1072 0.3506
Brugia malayi beta-lactamase family protein 0.0073 0.1126 0.2122
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0243 0.0318
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.2996 0.5781
Plasmodium falciparum peptidase, putative 0.0029 0.0144 0.1712
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0511 0.0918
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0641 0.2039
Brugia malayi prolyl oligopeptidase family protein 0.0077 0.1222 0.2309
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0513 0.0672
Mycobacterium ulcerans hypothetical protein 0.0073 0.1126 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.1126 1
Schistosoma mansoni myelin transcription factor 1 myt1 0.0061 0.0856 0.1121
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0689 0.0853
Echinococcus multilocularis acylamino acid releasing enzyme 0.0029 0.0144 0.0188
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0689 0.1267
Leishmania major hypothetical protein, conserved 0.0073 0.1126 0.3689
Toxoplasma gondii thioredoxin reductase 0.0046 0.0515 0.1613
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.1126 0.0644
Loa Loa (eye worm) hypothetical protein 0.0073 0.1126 0.1428
Leishmania major trypanothione reductase 0.0046 0.0515 0.1613
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0511 0.0669
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.2107 0.1678

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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