Detailed information for compound 656115

Basic information

Technical information
  • TDR Targets ID: 656115
  • Name: N-[2-(3-bromophenyl)-1,3-benzoxazol-5-yl]-4-m ethoxy-3-nitrobenzamide
  • MW: 468.257 | Formula: C21H14BrN3O5
  • H donors: 1 H acceptors: 4 LogP: 4.75 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1[N+](=O)[O-])C(=O)Nc1ccc2c(c1)nc(o2)c1cccc(c1)Br
  • InChi: 1S/C21H14BrN3O5/c1-29-19-7-5-12(10-17(19)25(27)28)20(26)23-15-6-8-18-16(11-15)24-21(30-18)13-3-2-4-14(22)9-13/h2-11H,1H3,(H,23,26)
  • InChiKey: INBCACWPLZUZQW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[2-(3-bromophenyl)-1,3-benzoxazol-5-yl]-4-methoxy-3-nitro-benzamide
  • EU-0034497
  • ChemDiv1_000501
  • Oprea1_069605

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax vivapain-2 0.0565 0.312 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0232 0.125 0.125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0133 0.0133
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0042 0.0042
Trypanosoma cruzi cysteine protease, putative 0.0367 0.2008 0.2001
Entamoeba histolytica hypothetical protein 0.0037 0.0158 0.0482
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Schistosoma mansoni hypothetical protein 0.0173 0.0923 0.0923
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0008 0.00000016492
Giardia lamblia Hypothetical protein 0.0232 0.125 0.1243
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.125 0.125
Schistosoma mansoni inositol monophosphatase 0.004 0.0176 0.0176
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Schistosoma mansoni lamin 0.0028 0.0106 0.0106
Giardia lamblia Cathepsin L precursor 0.0232 0.125 0.1243
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0232 0.125 0.3991
Plasmodium falciparum serine repeat antigen 4 0.0232 0.125 0.3991
Giardia lamblia Cathepsin B precursor 0.1793 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Brugia malayi MH2 domain containing protein 0.0126 0.0659 0.0652
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0073 0.0065
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0073 0.021
Brugia malayi Cathepsin L-like precursor 0.0135 0.071 0.0702
Echinococcus multilocularis cysteine protease 0.0565 0.312 0.312
Onchocerca volvulus 0.0565 0.312 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0133 0.0125
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1793 1 1
Brugia malayi Inositol-1 0.004 0.0176 0.0169
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0232 0.125 0.1243
Onchocerca volvulus 0.0028 0.0106 0.0316
Loa Loa (eye worm) cysteine protease 0.0565 0.312 0.3114
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Trichomonas vaginalis ran, putative 0.0022 0.0073 0.0073
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0321 0.028
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0327 0.0327
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0232 0.125 0.3991
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0565 0.312 0.312
Giardia lamblia Cathepsin B precursor 0.1793 1 1
Echinococcus granulosus snurportin 1 0.0315 0.1716 0.1716
Onchocerca volvulus 0.0232 0.125 0.3991
Loa Loa (eye worm) RNA binding protein 0.0067 0.0327 0.0319
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0565 0.312 0.312
Schistosoma mansoni cathepsin S (C01 family) 0.0232 0.125 0.125
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0232 0.125 0.3991
Echinococcus multilocularis microtubule associated protein 2 0.0706 0.3908 0.3908
Brugia malayi Papain family cysteine protease containing protein 0.0565 0.312 0.3114
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0158 0.0158
Echinococcus granulosus cathepsin L cysteine protease 0.0367 0.2008 0.2008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.125 0.125
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0232 0.125 0.3991
Toxoplasma gondii cathepsin CPL 0.0565 0.312 0.3114
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0321 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0232 0.125 0.3991
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0327 0.0327
Echinococcus granulosus cathepsin L 0.0232 0.125 0.125
Trypanosoma cruzi cysteine proteinase, putative 0.0367 0.2008 0.2001
Entamoeba histolytica hypothetical protein 0.0037 0.0158 0.0482
Treponema pallidum DNA ligase (lig) 0.001 0.0008 1
Giardia lamblia Cathepsin B precursor 0.0232 0.125 0.1243
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1793 1 1
Trichomonas vaginalis set domain proteins, putative 0.0257 0.1394 0.1394
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0117 0.0109
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Trypanosoma brucei cysteine peptidase C (CPC) 0.1793 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0367 0.2008 0.6427
Loa Loa (eye worm) hypothetical protein 0.0148 0.078 0.0773
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0327 0.0327
Echinococcus granulosus geminin 0.0173 0.0923 0.0923
Trypanosoma cruzi cysteine peptidase, putative 0.0367 0.2008 0.2001
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0232 0.125 0.1243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.043 0.2362 0.2362
Brugia malayi hypothetical protein 0.0037 0.0158 0.015
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0367 0.2008 0.2008
Echinococcus granulosus nibrin 0.001 0.0008 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1793 1 1
Plasmodium falciparum serine repeat antigen 7 0.0232 0.125 0.3991
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0015
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0565 0.312 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0042 0.0034
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0232 0.125 0.3991
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0367 0.2008 0.2008
Loa Loa (eye worm) hypothetical protein 0.0232 0.125 0.1243
Echinococcus multilocularis nibrin 0.001 0.0008 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0085 0.0085
Plasmodium vivax vivapain-2 0.0565 0.312 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0321 0.0321
Plasmodium vivax vivapain-3 0.0367 0.2008 0.6427
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.125 0.125
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0565 0.312 0.3114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Giardia lamblia Cathepsin B precursor 0.0232 0.125 0.1243
Onchocerca volvulus 0.0565 0.312 1
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0042
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0008
Plasmodium falciparum serine repeat antigen 5 0.0232 0.125 0.3991
Brugia malayi Cathepsin L-like precursor 0.0565 0.312 0.3114
Toxoplasma gondii cathepsin CPC1 0.0232 0.125 0.1243
Brugia malayi Cathepsin L-like precursor 0.0565 0.312 0.3114
Plasmodium vivax unspecified product 0.0232 0.125 0.3991
Plasmodium vivax importin-beta 2, putative 0.003 0.0117 0.035
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0008
Loa Loa (eye worm) cathepsin B 0.1793 1 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1793 1 1
Plasmodium vivax vivapain-1 0.0367 0.2008 0.6427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.125 0.125
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0042 0.011
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Giardia lamblia Cathepsin L precursor 0.0232 0.125 0.1243
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0858 0.4758 0.4758
Plasmodium vivax serine-repeat antigen (SERA) 0.0232 0.125 0.3991
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Schistosoma mansoni hypothetical protein 0.0315 0.1716 0.1716
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0.0008 0.0445
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Loa Loa (eye worm) hypothetical protein 0.0232 0.125 0.1243
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0133 0.0133
Brugia malayi isocitrate dehydrogenase 0.0016 0.0042 0.0034
Entamoeba histolytica cysteine protease, putative 0.0565 0.312 1
Loa Loa (eye worm) hypothetical protein 0.0232 0.125 0.1243
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0008 0.0008
Entamoeba histolytica cysteine protease, putative 0.0232 0.125 0.3991
Onchocerca volvulus 0.0565 0.312 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0073 0.0073
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0176 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0135 0.071 0.0702
Entamoeba histolytica hypothetical protein 0.0037 0.0158 0.0482
Trypanosoma cruzi cruzipain precursor, putative 0.0565 0.312 0.3114
Echinococcus multilocularis snurportin 1 0.0315 0.1716 0.1716
Trypanosoma cruzi major cysteine proteinase, putative 0.0232 0.125 0.1243
Schistosoma mansoni cathepsin F (C01 family) 0.0565 0.312 0.312
Entamoeba histolytica cysteine protease, putative 0.0232 0.125 0.3991
Plasmodium vivax serine-repeat antigen (SERA) 0.0232 0.125 0.3991
Brugia malayi cathepsin L precursor 0.0232 0.125 0.1243
Giardia lamblia Cysteine protease 0.0232 0.125 0.1243
Echinococcus granulosus cathepsin L 0.0367 0.2008 0.2008
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Giardia lamblia Cathepsin B precursor 0.1793 1 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0008
Echinococcus multilocularis lamin 0.0028 0.0106 0.0106
Brugia malayi Cathepsin L-like cysteine proteinase 0.043 0.2362 0.2356
Brugia malayi Muscleblind-like protein 0.0148 0.078 0.0773
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0565 0.312 0.3114
Brugia malayi RNA binding protein 0.0067 0.0327 0.0319
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0034 0.0026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.125 0.1243
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0085 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Entamoeba histolytica cysteine protease, putative 0.0232 0.125 0.3991
Onchocerca volvulus 0.0032 0.0133 0.0403
Onchocerca volvulus 0.0565 0.312 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1793 1 1
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Plasmodium falciparum serine repeat antigen 1 0.0232 0.125 0.3991
Brugia malayi cathepsin Z-like cysteine proteinase 0.0232 0.125 0.1243
Loa Loa (eye worm) hypothetical protein 0.1793 1 1
Brugia malayi Pre-SET motif family protein 0.0032 0.0133 0.0125
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0327 0.0327
Schistosoma mansoni topbp1 0.001 0.0008 0.0008
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0232 0.125 0.3991
Brugia malayi Pax transcription factor protein 2 0.0246 0.1331 0.1325
Echinococcus granulosus lamin dm0 0.0028 0.0106 0.0106
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.2008 0.2001
Echinococcus multilocularis musashi 0.0028 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0232 0.125 0.1243
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0133 0.0133
Entamoeba histolytica cysteine proteinase, putative 0.0367 0.2008 0.6427
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.043 0.2362 0.2356
Trypanosoma cruzi cysteine proteinase, putative 0.0367 0.2008 0.2001
Entamoeba histolytica cysteine proteinase, putative 0.0367 0.2008 0.6427
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0147 0.0139
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0042 0.0034
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0232 0.125 0.3991
Loa Loa (eye worm) hypothetical protein 0.0232 0.125 0.1243
Brugia malayi TAR-binding protein 0.0067 0.0327 0.0319
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.125 0.125
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0008 0.0008
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.021
Entamoeba histolytica cysteine proteinase 1, putative 0.0367 0.2008 0.6427
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0176 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0367 0.2008 0.2008
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0367 0.2008 0.2001
Onchocerca volvulus Cathepsin L homolog 0.0565 0.312 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0026 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0327 0.0327
Entamoeba histolytica hypothetical protein 0.0232 0.125 0.3991
Entamoeba histolytica cysteine protease, putative 0.0232 0.125 0.3991
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0232 0.125 0.3991
Echinococcus multilocularis GPCR, family 2 0.0016 0.0042 0.0042
Echinococcus multilocularis cysteine protease 0.0565 0.312 0.312
Onchocerca volvulus 0.0565 0.312 1
Schistosoma mansoni inositol monophosphatase 0.004 0.0176 0.0176
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0133 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.125 0.125
Giardia lamblia Cathepsin L precursor 0.0232 0.125 0.1243
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.125 0.125
Echinococcus granulosus cathepsin l1 0.043 0.2362 0.2362
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0008 0.0008
Giardia lamblia Cysteine protease 0.0232 0.125 0.1243
Loa Loa (eye worm) pax transcription factor protein 2 0.0246 0.1331 0.1325
Brugia malayi intermediate filament protein 0.0028 0.0106 0.0098
Brugia malayi Cathepsin L-like precursor 0.0565 0.312 0.3114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1793 1 1
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0042 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0008 0.0008
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0042 0.1307
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0073 0.0065
Trypanosoma cruzi cysteine peptidase, putative 0.0565 0.312 0.3114
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Entamoeba histolytica cysteine protease, putative 0.0232 0.125 0.3991
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0042 0.0034
Onchocerca volvulus Cathepsin F homolog 0.0565 0.312 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0176 0.549
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0232 0.125 0.3991
Giardia lamblia Cathepsin B precursor 0.0232 0.125 0.1243
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0176 0.0169
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0232 0.125 0.1243
Loa Loa (eye worm) hypothetical protein 0.043 0.2362 0.2356
Schistosoma mansoni cathepsin F (C01 family) 0.043 0.2362 0.2362
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0133 0.0133
Echinococcus granulosus lamin 0.0028 0.0106 0.0106
Toxoplasma gondii preprocathepsin c precursor, putative 0.0232 0.125 0.1243
Schistosoma mansoni hypothetical protein 0.0173 0.0923 0.0923
Onchocerca volvulus 0.0246 0.1331 0.4253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Giardia lamblia Cathepsin L precursor 0.0232 0.125 0.1243
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.125 0.125
Loa Loa (eye worm) hypothetical protein 0.0051 0.0237 0.023
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0042 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.125 0.125
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.125 0.125
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0321 0.0321
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Entamoeba histolytica cysteine protease, putative 0.0232 0.125 0.3991
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0232 0.125 0.125
Loa Loa (eye worm) ctsf protein 0.0565 0.312 0.3114
Loa Loa (eye worm) fibroinase 0.0565 0.312 0.3114
Entamoeba histolytica cysteine proteinase, putative 0.0565 0.312 1
Brugia malayi fibroinase precursor 0.0232 0.125 0.1243
Leishmania major cathepsin L-like protease 0.0565 0.312 0.3091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.125 0.125
Schistosoma mansoni cathepsin F (C01 family) 0.0565 0.312 0.312
Plasmodium falciparum serine repeat antigen 6 0.0232 0.125 0.3991
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Onchocerca volvulus Cathepsin L homolog 0.0565 0.312 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Plasmodium falciparum serine repeat antigen 8 0.0232 0.125 0.3991
Echinococcus granulosus importin subunit beta 1 0.003 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0232 0.125 0.1243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0226 0.1219 0.1212
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0232 0.125 0.125
Giardia lamblia Encystation-specific protease 0.0232 0.125 0.1243
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0042 0.0034
Brugia malayi cathepsin L-like cysteine proteinase 0.0232 0.125 0.1243
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0042
Trypanosoma cruzi cysteine peptidase, putative 0.0565 0.312 0.3114
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0158 0.0158
Echinococcus multilocularis geminin 0.0173 0.0923 0.0923
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0232 0.125 0.1243
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0106 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Loa Loa (eye worm) hypothetical protein 0.0028 0.0106 0.0098
Onchocerca volvulus 0.0565 0.312 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0367 0.2008 0.2008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Loa Loa (eye worm) MH2 domain-containing protein 0.0126 0.0659 0.0652
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.125 0.1243
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0008 0.0008
Echinococcus multilocularis lamin dm0 0.0028 0.0106 0.0106
Toxoplasma gondii cathepsin CPC2 0.0232 0.125 0.1243
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0176 0.0176
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0042 0.0042
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.125 0.1243
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.125 0.125
Echinococcus multilocularis muscleblind protein 0.0148 0.078 0.078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.125 0.125
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0153 0.4756
Loa Loa (eye worm) hypothetical protein 0.0135 0.071 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0008
Schistosoma mansoni DNA ligase IV 0.001 0.0008 0.0008
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0565 0.312 0.312
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0232 0.125 0.125
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0327 0.0327
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Loa Loa (eye worm) hypothetical protein 0.003 0.0117 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0103 0.0095
Echinococcus multilocularis cathepsin L cysteine protease 0.0565 0.312 0.312
Echinococcus granulosus tar DNA binding protein 0.0067 0.0327 0.0327
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0176 0.0135
Toxoplasma gondii cathepsin B 0.1793 1 1
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0327 0.0319
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0321 1
Echinococcus granulosus intermediate filament protein 0.0028 0.0106 0.0106
Plasmodium vivax SET domain protein, putative 0.0032 0.0133 0.0403
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0232 0.125 0.125
Echinococcus multilocularis importin subunit beta 1 0.003 0.0117 0.0117
Echinococcus granulosus microtubule associated protein 2 0.0706 0.3908 0.3908
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0135 0.071 0.0702
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0176 0.0176
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0321 1
Giardia lamblia Hypothetical protein 0.0232 0.125 0.1243
Leishmania major GTP-binding protein, putative 0.0022 0.0073 0.0031
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0176 0.0176
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0232 0.125 0.125
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Brugia malayi cathepsin L-like precursor 0.043 0.2362 0.2356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.125 0.125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.125 0.125
Brugia malayi Cathepsin L-like precursor 0.0565 0.312 0.3114
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1793 1 1
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0176 0.0176
Schistosoma mansoni ran 0.0022 0.0073 0.0073
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0117 0.0109
Trypanosoma cruzi cysteine peptidase, putative 0.0565 0.312 0.3114
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0565 0.312 0.312
Echinococcus granulosus cathepsin l1 0.0565 0.312 0.312
Loa Loa (eye worm) inositol-1 0.004 0.0176 0.0169
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0327 0.0319
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0176 0.0541
Onchocerca volvulus 0.0028 0.0106 0.0316
Onchocerca volvulus 0.0565 0.312 1
Brugia malayi Cathepsin L-like precursor 0.0565 0.312 0.3114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.125 0.125
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0117 0.0109
Schistosoma mansoni hypothetical protein 0.0035 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0037 0.0158 0.0158
Echinococcus granulosus cysteine protease 0.0367 0.2008 0.2008
Entamoeba histolytica cysteine proteinase, putative 0.0367 0.2008 0.6427
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0153 1
Giardia lamblia Cysteine protease 0.0232 0.125 0.1243
Schistosoma mansoni importin beta-1 0.003 0.0117 0.0117
Entamoeba histolytica hypothetical protein 0.0037 0.0158 0.0482
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0026 0.0026
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0232 0.125 0.3991
Echinococcus multilocularis cathepsin L 0.0232 0.125 0.125
Giardia lamblia Cathepsin L-like protease 0.0232 0.125 0.1243
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0042 0.0042
Leishmania major importin beta-1 subunit, putative 0.0024 0.0085 0.0044
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.071 0.0702
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0367 0.2008 0.2001
Plasmodium vivax unspecified product 0.0367 0.2008 0.6427
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.125 0.1243
Onchocerca volvulus 0.043 0.2362 0.7564
Brugia malayi Papain family cysteine protease containing protein 0.0367 0.2008 0.2001
Echinococcus multilocularis cathepsin b 0.1793 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0321 0.0314
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0042 0.0034
Loa Loa (eye worm) hypothetical protein 0.043 0.2362 0.2356
Trypanosoma cruzi major cysteine proteinase, putative 0.0232 0.125 0.1243
Trypanosoma cruzi cysteine peptidase, putative 0.0565 0.312 0.3114
Leishmania major cysteine peptidase A (CPA) 0.0565 0.312 0.3091
Loa Loa (eye worm) hypothetical protein 0.0035 0.0147 0.0139
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0042 0.0042
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0026 0.0018
Schistosoma mansoni intermediate filament proteins 0.0028 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0016 0.0042 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.071 0.0702
Onchocerca volvulus 0.0257 0.1394 0.4454
Entamoeba histolytica cysteine proteinase 2 0.0367 0.2008 0.6427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0008 0.00000052957
Schistosoma mansoni cathepsin s 0.0135 0.071 0.071
Brugia malayi Cathepsin L-like precursor 0.043 0.2362 0.2356
Brugia malayi cathepsin F-like cysteine proteinase 0.0135 0.071 0.0702
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Echinococcus granulosus replication factor c subunit 1 0.001 0.0008 0.0008
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0008 0.0513
Brugia malayi RNA, U transporter 1 0.0084 0.0422 0.0414
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.125 0.125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0042 0.0042
Brugia malayi Cathepsin L-like precursor 0.0565 0.312 0.3114
Onchocerca volvulus Cathepsin L homolog 0.0232 0.125 0.3991
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0042 0.0042
Giardia lamblia Cathepsin L precursor 0.0232 0.125 0.1243
Brugia malayi Papain family cysteine protease containing protein 0.0367 0.2008 0.2001
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0085 0.0078
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Plasmodium falciparum cysteine proteinase falcipain 1 0.0367 0.2008 0.6427
Echinococcus granulosus GPCR family 2 0.0016 0.0042 0.0042
Echinococcus granulosus muscleblind protein 0.0148 0.078 0.078
Echinococcus multilocularis cathepsin L cysteine protease 0.0565 0.312 0.312
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0237 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0232 0.125 0.125
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0565 0.312 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0034 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.125 0.125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0008 0.0008
Entamoeba histolytica Ran family GTPase 0.0022 0.0073 0.021
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.125 0.1243
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0073 0.0073
Brugia malayi cathepsin F-like cysteine proteinase 0.0232 0.125 0.1243
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0232 0.125 0.125
Giardia lamblia Cathepsin B precursor 0.0232 0.125 0.1243
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0073 0.0065
Plasmodium falciparum serine repeat antigen 3 0.0232 0.125 0.3991
Schistosoma mansoni microtubule-associated protein tau 0.0706 0.3908 0.3908
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1793 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.043 0.2362 0.2362
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.125 0.1243
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0073 0.0065
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0237 0.023
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0232 0.125 0.1243
Plasmodium falciparum cysteine proteinase falcipain 3 0.0565 0.312 1
Brugia malayi Pre-SET motif family protein 0.0226 0.1219 0.1212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Brugia malayi cathepsin Z-like cysteine proteinase 0.0232 0.125 0.1243
Echinococcus granulosus cathepsin l cysteine peptidase 0.0565 0.312 0.312
Loa Loa (eye worm) hypothetical protein 0.0135 0.071 0.0702
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0042 0.011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1793 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0565 0.312 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0133 0.0133
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.125 0.125
Echinococcus granulosus cathepsin b 0.1793 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0367 0.2008 0.2008
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0106 0.0098
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0073 0.0065
Echinococcus multilocularis cathepsin b 0.1793 1 1
Plasmodium vivax unspecified product 0.0135 0.071 0.2255
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0106 0.0098
Echinococcus multilocularis cathepsin L 0.0367 0.2008 0.2008
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0008 0.0244
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0158 0.0158
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0321 0.0321
Giardia lamblia Cathepsin L-like protease 0.0232 0.125 0.1243
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0042 0.0034
Giardia lamblia Cathepsin B precursor 0.0232 0.125 0.1243
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0042 0.0042
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0232 0.125 0.3991
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0176 0.0176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0565 0.312 0.312
Echinococcus granulosus cathepsin b 0.1793 1 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0232 0.125 0.3991
Loa Loa (eye worm) hypothetical protein 0.043 0.2362 0.2356
Loa Loa (eye worm) hypothetical protein 0.0135 0.071 0.0702
Plasmodium falciparum serine repeat antigen 2 0.0232 0.125 0.3991
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Plasmodium falciparum serine repeat antigen 9 0.0232 0.125 0.3991
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0315 0.1716 0.171
Schistosoma mansoni cathepsin B (C01 family) 0.0232 0.125 0.125
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0237 0.023
Plasmodium falciparum importin beta, putative 0.003 0.0117 0.035
Schistosoma mansoni hypothetical protein 0.0016 0.0042 0.0042
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0232 0.125 0.3991
Entamoeba histolytica hypothetical protein 0.0024 0.0085 0.0249
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Loa Loa (eye worm) transcription factor SMAD2 0.0126 0.0659 0.0652
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0042 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0565 0.312 0.312
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0232 0.125 0.3991
Loa Loa (eye worm) hypothetical protein 0.0032 0.0133 0.0125
Echinococcus granulosus cathepsin L cysteine proteinase 0.0565 0.312 0.312
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0327 0.0319
Schistosoma mansoni cathepsin C 0.0232 0.125 0.125
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0126 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.125 0.125
Brugia malayi Importin beta-1 subunit 0.003 0.0117 0.0109
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0321 0.0321
Loa Loa (eye worm) hypothetical protein 0.0148 0.078 0.0773
Giardia lamblia Cysteine protease 0.0232 0.125 0.1243
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0176 0.0169
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0042 0.0034
Entamoeba histolytica cysteine proteinase, putative 0.043 0.2362 0.7564
Loa Loa (eye worm) hypothetical protein 0.0565 0.312 0.3114
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0042 0.0042
Schistosoma mansoni topbp1 0.001 0.0008 0.0008
Echinococcus multilocularis muscleblind protein 1 0.0148 0.078 0.078
Schistosoma mansoni ran 0.0022 0.0073 0.0073
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0042 0.0034
Schistosoma mansoni lamin 0.0028 0.0106 0.0106
Chlamydia trachomatis DNA ligase 0.001 0.0008 0.5
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0321 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0133 0.0133
Brugia malayi Cathepsin L-like precursor 0.043 0.2362 0.2356
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0042 0.0042
Giardia lamblia Cathepsin L precursor 0.0232 0.125 0.1243
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0176 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0565 0.312 0.3114
Entamoeba histolytica cysteine protease, putative 0.0367 0.2008 0.6427

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.