Detailed information for compound 702942

Basic information

Technical information
  • TDR Targets ID: 702942
  • Name: 5-[(4-chlorophenyl)-[4-(4-methoxyphenyl)piper azin-1-yl]methyl]-2-ethyl-[1,3]thiazolo[2,3-e ][1,2,4]triazol-6-ol
  • MW: 484.014 | Formula: C24H26ClN5O2S
  • H donors: 1 H acceptors: 3 LogP: 5.42 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1nn2c(n1)sc(c2O)C(c1ccc(cc1)Cl)N1CCN(CC1)c1ccc(cc1)OC
  • InChi: 1S/C24H26ClN5O2S/c1-3-20-26-24-30(27-20)23(31)22(33-24)21(16-4-6-17(25)7-5-16)29-14-12-28(13-15-29)18-8-10-19(32-2)11-9-18/h4-11,21,31H,3,12-15H2,1-2H3
  • InChiKey: XEBQUJCYZGEZLW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[(4-chlorophenyl)-[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-2-ethyl-thiazolo[2,3-e][1,2,4]triazol-6-ol
  • 5-[(4-chlorophenyl)-[4-(4-methoxyphenyl)-1-piperazinyl]methyl]-2-ethyl-6-thiazolo[2,3-e][1,2,4]triazolol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0111 0.024
Schistosoma mansoni protein kinase 0.0032 0.0583 0.18
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0723
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0543 0.0373
Brugia malayi hypothetical protein 0.0014 0.0177 0.0382
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0543 0.0543
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0208 0.0488
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0584 0.0414
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.2442 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0823
Loa Loa (eye worm) RasGEF domain-containing protein 0.0007 0.0008 0.0017
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0374 0.1194
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.1213 0.3743
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0253 0.0383
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0558 0.1208
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.2442 0.5288
Echinococcus granulosus caspase 0.0018 0.0253 0.1035
Loa Loa (eye worm) hypothetical protein 0.0025 0.0423 0.0916
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0545
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0115 0.2533 1
Toxoplasma gondii sugar transporter ST3 0.0014 0.0177 0.0267
Schistosoma mansoni protein kinase 0.0032 0.0583 0.18
Plasmodium vivax CDK-related protein kinase 6, putative 0.0433 1 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0076 0.0164
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0702 0.2873
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0177 0.0382
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0177 0.0382
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0374 0.0872
Onchocerca volvulus 0.0014 0.0177 0.0366
Brugia malayi Sugar transporter family protein 0.0014 0.0177 0.0382
Trypanosoma cruzi metacaspase, putative 0.0018 0.0253 0.1005
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0374 0.1504
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0208 0.0488
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0527 0.2159
Brugia malayi hypothetical protein 0.0014 0.0177 0.0382
Leishmania major protein kinase, putative 0.0032 0.0583 0.2388
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0723
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.2232 0.3378
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0584 0.0584
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0177 0.0723
Trypanosoma cruzi hexose transporter 0.0032 0.0582 0.2358
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0582 0.2358
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0584 0.0884
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0102 0.2232 0.4832
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0111 0.024
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0543 0.0822
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Trypanosoma brucei protein kinase, putative 0.0053 0.1074 0.396
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0583 0.1795
Schistosoma mansoni caspase-3 (C14 family) 0.0018 0.0253 0.078
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0543 0.2199
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.1074 0.4396
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0177 0.0267
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trypanosoma brucei glucose transporter 1E 0.0032 0.0582 0.1789
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0582 0.2358
Trypanosoma cruzi metacaspase, putative 0.0018 0.0253 0.1005
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0543 0.2199
Onchocerca volvulus 0.0014 0.0177 0.0366
Schistosoma mansoni dep domain containing protein 0.001 0.0076 0.0233
Onchocerca volvulus 0.0014 0.0177 0.0366
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0208 0.0208
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.1074 0.4378
Leishmania major glucose transporter, lmgt3 0.0032 0.0582 0.2383
Schistosoma mansoni dishevelled 0.001 0.0076 0.0233
Echinococcus multilocularis son of sevenless 1 0.0007 0.0008 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0692
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0177 0.0692
Echinococcus multilocularis caspase 2 0.0058 0.1213 0.4967
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0208 0.0823
Onchocerca volvulus 0.0014 0.0177 0.0366
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0253 0.1005
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0177 0.0692
Onchocerca volvulus 0.0014 0.0177 0.0366
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0177 0.0353
Brugia malayi RasGEF domain containing protein 0.0007 0.0008 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0558 0.1208
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0177 0.0353
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0208 1
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0558 0.2284
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Brugia malayi hypothetical protein 0.0037 0.0702 0.1519
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0115 0.2533 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0583 0.1263
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0018 0.0253 0.1035
Loa Loa (eye worm) hypothetical protein 0.0204 0.4619 1
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.1074 0.4396
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0103 0.2262 0.8853
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Loa Loa (eye worm) RasGEF domain-containing protein 0.0007 0.0008 0.0017
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Schistosoma mansoni hypothetical protein 0.0041 0.0801 0.2471
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Brugia malayi 6-phosphofructokinase 0.0111 0.2442 0.5288
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Mycobacterium ulcerans sugar transporter 0.0014 0.0177 0.0353
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0177 0.0382
Plasmodium falciparum hexose transporter 0.0102 0.2232 0.2232
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0558 0.1721
Brugia malayi N-terminal motif family protein 0.0204 0.4619 1
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0723
Loa Loa (eye worm) hypothetical protein 0.0058 0.1213 0.2626
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0007 0.0008 0.0025
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0677 0.2747
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0294 0.0497
Echinococcus granulosus caspase 2 0.0058 0.1213 0.4967
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0253 0.1005
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0076 0.0309
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0177 0.0723
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0253 0.1005
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0558 0.2258
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0246 0.0976
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0007 0.0008 0.0033
Plasmodium vivax metacaspase 1, putative 0.0018 0.0253 0.0078
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0374 0.0359
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0677 0.277
Echinococcus granulosus segment polarity protein dishevelled 0.001 0.0076 0.0309
Schistosoma mansoni regulator of G protein signaling 0.001 0.0076 0.0233
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0582 0.2358
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0677 0.0677
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0558 0.118
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0583 0.1263
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0208 0.0853
Loa Loa (eye worm) glutathione reductase 0.0045 0.0902 0.1953
Loa Loa (eye worm) sugar transporter 0.0102 0.2232 0.4832
Mycobacterium tuberculosis Probable reductase 0.0103 0.2262 0.8853
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0076 0.0309
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0253 0.0383
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0177 0.0692
Echinococcus granulosus apoptotic protease activating factor 1 0.0041 0.0801 0.3278
Loa Loa (eye worm) hypothetical protein 0.0031 0.0558 0.1208
Brugia malayi Sugar transporter family protein 0.0102 0.2232 0.4832
Brugia malayi Cam kinase protein 1 0.0032 0.0583 0.1263
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0177 0.0353
Echinococcus multilocularis caspase 0.0018 0.0253 0.1035
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0543 0.0822
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0076 0.0164
Mycobacterium tuberculosis Probable dehydrogenase 0.0103 0.2262 0.8853
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0177 0.0545
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0208 0.0853
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0076 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0692
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0007 0.0008 0.0033
Onchocerca volvulus 0.0014 0.0177 0.0366
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0177 0.0382
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0584 0.0884
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0582 0.2358
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0543 1
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0584 0.0414
Trypanosoma brucei metacaspase 5, putative 0.0018 0.0253 0.0336
Plasmodium falciparum glutathione reductase 0.0045 0.0902 0.0902
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0374 0.1532
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0007 0.0008 0.0025
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.1074 1
Brugia malayi RasGEF domain containing protein 0.0007 0.0008 0.0017
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Loa Loa (eye worm) thioredoxin reductase 0.0045 0.0902 0.1953
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.1074 0.4378
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0677 0.0509
Entamoeba histolytica hypothetical protein 0.0037 0.0702 0.2849
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0545
Leishmania major hypothetical protein, conserved 0.0014 0.0177 0.0723
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Plasmodium falciparum thioredoxin reductase 0.0016 0.0208 0.0208
Brugia malayi Thioredoxin reductase 0.0045 0.0902 0.1953
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0677 0.2207
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0208 0.0135
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.2232 0.6887
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.2442 1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0543 0.2199
Echinococcus multilocularis apoptotic protease activating factor 1 0.0041 0.0801 0.3278
Loa Loa (eye worm) hypothetical protein 0.0018 0.0253 0.0547
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0583 0.18
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Onchocerca volvulus 0.0014 0.0177 0.0366
Brugia malayi phosphofructokinase 0.0111 0.2442 0.5288
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0374 0.081
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.1074 0.4396
Onchocerca volvulus 0.0014 0.0177 0.0366
Mycobacterium tuberculosis Probable oxidoreductase 0.0115 0.2533 1
Brugia malayi hypothetical protein 0.0014 0.0177 0.0382
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0374 0.1154
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.2442 0.9617
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0543 0.2199
Echinococcus multilocularis caspase 8 0.0018 0.0253 0.1035
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0076 0.0164
Trypanosoma brucei metacaspase MCA2 0.0018 0.0253 0.0336
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0582 0.2358
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0723
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0103 0.2262 0.8853
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0853
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.2442 1
Plasmodium falciparum mitogen-activated protein kinase 2 0.0165 0.3715 0.3715
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0208 0.0823
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0135 0.0292
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0208 0.0853
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0208 0.0032
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0558 0.4249
Trypanosoma brucei trypanothione reductase 0.0045 0.0902 0.3202
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0916 0.3752
Brugia malayi Cell death protein 3 precursor 0.0058 0.1213 0.2626
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0007 0.0008 0.0033
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0076 0.0164
Entamoeba histolytica protein kinase, putative 0.0032 0.0583 0.2363
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0853
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0543 0.0543
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0723
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.1074 0.4396
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0692
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0723
Brugia malayi 6-phosphofructokinase 0.0111 0.2442 0.5288
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.2442 1
Plasmodium falciparum metacaspase 1 0.0018 0.0253 0.0253
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0723
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0208 0.0643
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0177 0.0692
Leishmania major trypanothione reductase 0.0045 0.0902 0.3694
Entamoeba histolytica hypothetical protein 0.0037 0.0702 0.2849
Trypanosoma brucei Metacaspase-4 0.0018 0.0253 0.0336
Schistosoma mansoni glucose transporter 0.0014 0.0177 0.0545
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Trypanosoma brucei metacaspase 0.0018 0.0253 0.0336
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0916 0.3752
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Brugia malayi major facilitator superfamily protein 0.0014 0.0177 0.0382
Echinococcus granulosus Protein son of sevenless 0.0007 0.0008 0.0033
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0204 0.4619 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0543 0.2199
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0208 0.014
Onchocerca volvulus 0.0014 0.0177 0.0366
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0558 0.1721
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0208 0.0823
Trypanosoma brucei glucose transporter 2A 0.0032 0.0582 0.1789
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0208 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0208 0.2548
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.1074 0.396
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.1074 0.4378
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0374 0.1532
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0177 0.0723
Schistosoma mansoni glucose transport protein 0.0102 0.2232 0.6886
Onchocerca volvulus 0.001 0.0076 0.0146
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.2232 0.6887
Loa Loa (eye worm) hypothetical protein 0.001 0.0076 0.0164
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0374 0.6236
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0558 0.2258
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.2442 0.5288
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0543 0.2199
Echinococcus granulosus segment polarity protein dishevelled 0.001 0.0076 0.0309
Onchocerca volvulus 0.0014 0.0177 0.0366
Brugia malayi glutathione reductase 0.0045 0.0902 0.1953
Schistosoma mansoni dishevelled 0.001 0.0076 0.0233
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0723
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0115 0.2533 1
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0558 0.1208
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0253 0.1005
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0902 0.3673
Loa Loa (eye worm) hypothetical protein 0.0032 0.0583 0.1263
Onchocerca volvulus 0.0014 0.0177 0.0366
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Onchocerca volvulus 0.0014 0.0177 0.0366
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Echinococcus granulosus caspase 8 0.0018 0.0253 0.1035
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.2232 0.9137
Trypanosoma cruzi metacaspase, putative 0.0018 0.0253 0.1005
Entamoeba histolytica hypothetical protein 0.0037 0.0702 0.2849
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0177 0.0382
Toxoplasma gondii sugar transporter ST1 0.0014 0.0177 0.0267
Loa Loa (eye worm) RasGEF domain-containing protein 0.0007 0.0008 0.0017
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0177 0.0692
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0584 0.0414
Loa Loa (eye worm) sugar transporter 0.0014 0.0177 0.0382
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.1074 0.4396
Plasmodium vivax thioredoxin reductase, putative 0.0045 0.0902 0.0739
Toxoplasma gondii thioredoxin reductase 0.0045 0.0902 0.1365
Brugia malayi MAP kinase sur-1 0.0053 0.1074 0.2325
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Toxoplasma gondii hypothetical protein 0.001 0.0076 0.0114
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.2442 0.7537
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0677 0.1024
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.1074 0.2325
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0374 0.1532
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.2442 1
Plasmodium falciparum metacaspase-like protein 0.0018 0.0253 0.0253
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0584 0.0584
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.1074 0.3313
Toxoplasma gondii protein kinase, putative 0.0288 0.6607 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0374 0.0374
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0584 0.0414
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0017
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0103 0.2262 0.8793
Brugia malayi DIX domain containing protein 0.001 0.0076 0.0164
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0582 0.1789
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0018 0.0253 0.1035
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0208 0.0823
Loa Loa (eye worm) hypothetical protein 0.0007 0.0008 0.0017
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0177 0.0723
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0543 0.0822
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0584 0.0584
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.2442 1
Schistosoma mansoni hypothetical protein 0.0037 0.0702 0.2165
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0692
Brugia malayi major facilitator superfamily protein 0.0014 0.0177 0.0382
Entamoeba histolytica protein kinase, putative 0.0032 0.0583 0.2363
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0584 0.0884
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0823
Leishmania major glucose transporter, lmgt1 0.0032 0.0582 0.2383
Echinococcus granulosus son of sevenless 1 0.0007 0.0008 0.0033
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.2442 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0253 0.1005
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.2442 1
Echinococcus granulosus General substrate transporter 0.0088 0.1895 0.776
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Brugia malayi RasGEF domain containing protein 0.0007 0.0008 0.0017
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0677 0.2747
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.2442 1
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.001 0.0076 0.0309
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0208 0.0315
Onchocerca volvulus 0.0014 0.0177 0.0366
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0702 0.2165
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.1074 0.4396
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0177 0.0177
Brugia malayi N-terminal motif family protein 0.0007 0.0008 0.0017
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0543 0.2199
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0103 0.2262 0.8853
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.1074 0.4378
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0208 0.0208
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0543 0.0373
Echinococcus multilocularis segment polarity protein dishevelled 0.001 0.0076 0.0309
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0208 0.0315
Leishmania major glucose transporter, lmgt2 0.0032 0.0582 0.2383
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0018 0.0253 0.0547
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.2442 0.9597
Trypanosoma brucei metacaspase MCA3 0.0018 0.0253 0.0336
Echinococcus multilocularis segment polarity protein dishevelled 0.001 0.0076 0.0309
Schistosoma mansoni glucose transport protein 0.0102 0.2232 0.6886
Loa Loa (eye worm) hypothetical protein 0.0023 0.0374 0.081
Schistosoma mansoni protein kinase 0.0032 0.0583 0.18
Brugia malayi Sugar transporter family protein 0.0014 0.0177 0.0382
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.2232 0.9134
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0294 0.0497
Echinococcus granulosus ras GTP exchange factor 0.0007 0.0008 0.0033
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0076 0.0309
Leishmania major metacaspase, putative 0.0018 0.0253 0.1035
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0583 0.2388
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0584 0.0584
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0208 0.014
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0253 0.0078
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0543 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.1074 0.4378
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0545
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Onchocerca volvulus 0.0014 0.0177 0.0366
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.2442 1
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0374 0.2202
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0208 0.014
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0374 0.1154
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0103 0.2262 0.8853
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0582 0.2358
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Loa Loa (eye worm) hypothetical protein 0.0041 0.0801 0.1733
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0702 0.2873
Treponema pallidum NADH oxidase 0.0016 0.0208 0.0488
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0823
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0007 0.0008 0.0025
Entamoeba histolytica hypothetical protein 0.0037 0.0702 0.2849
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.2442 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0308 0.1234
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0582 0.1789
Schistosoma mansoni caspase-7 (C14 family) 0.0018 0.0253 0.078
Schistosoma mansoni hypothetical protein 0.0102 0.2232 0.6886
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0208 0.0451
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0582 0.2358
Plasmodium falciparum thioredoxin reductase 0.0045 0.0902 0.0902
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0018 0.0253 0.0383
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0007 0.0008 0.0033
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0543 0.1914
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0582 0.2358
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.001 0.0076 0.0233
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0583 0.2363
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0076 0.0309
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0018 0.0253 0.1005
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.2442 0.7537
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.1074 0.4378
Echinococcus granulosus Pleckstrin G protein interacting region 0.001 0.0076 0.0309
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0177 0.0723
Brugia malayi hypothetical protein 0.001 0.0076 0.0164
Trypanosoma cruzi metacaspase 5, putative 0.0018 0.0253 0.1005
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0045 0.0902 0.3079
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0584 0.0584
Brugia malayi N-terminal motif family protein 0.0007 0.0008 0.0017
Onchocerca volvulus Putative transporter 0.0014 0.0177 0.0366
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0374 0.0201
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0543 0.4088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0823
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0692
Plasmodium falciparum glutathione reductase 0.0016 0.0208 0.0208
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Echinococcus multilocularis General substrate transporter 0.0088 0.1895 0.776
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0374 0.1504
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.1213 0.2614
Schistosoma mansoni ras GTP exchange factor 0.0007 0.0008 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0543 0.2199
Echinococcus multilocularis ras GTP exchange factor 0.0007 0.0008 0.0033
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0677 0.277
Loa Loa (eye worm) hypothetical protein 0.001 0.0076 0.0164
Schistosoma mansoni glucose transport protein 0.0102 0.2232 0.6886
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0582 0.2358
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0527 0.2159
Echinococcus multilocularis Protein son of sevenless 0.0007 0.0008 0.0033
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.001 0.0076 0.0146
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0583 0.2388
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0545
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0102 0.2232 0.6887
Plasmodium vivax glutathione reductase, putative 0.0045 0.0902 0.0739
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0076 0.0233
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0582 0.2383
Loa Loa (eye worm) DIX domain-containing protein 0.001 0.0076 0.0164
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0823
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0582 0.2358
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0253 0.1005
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.2442 1
Trypanosoma cruzi metacaspase, putative 0.0018 0.0253 0.1005
Onchocerca volvulus 0.0014 0.0177 0.0366
Plasmodium falciparum protein kinase 7 0.0288 0.6607 0.6607
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0165 0.3715 0.5623
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0102 0.2232 0.4832
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.2232 0.9138
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0102 0.2232 0.9138
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0558 0.2284
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0208 0.0032
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.1074 0.4378
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0177 0.0692
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.1074 0.4378
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0208 0.0823
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Onchocerca volvulus 0.0041 0.0801 0.1719
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.2232 0.9137
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.2442 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0582 0.1789
Onchocerca volvulus 0.0014 0.0177 0.0366
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0692
Entamoeba histolytica hypothetical protein 0.0023 0.0374 0.1504
Loa Loa (eye worm) phosphofructokinase 0.0111 0.2442 0.5288
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.1074 0.1625
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0208 0.0853
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0208 0.014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.2232 0.9138
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.2442 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0208 0.0488
Trypanosoma brucei glucose transporter, putative 0.0032 0.0582 0.1789
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0102 0.2232 0.9138
Brugia malayi hypothetical protein 0.0041 0.0801 0.1733
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0208 0.0353
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0208 0.0823
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0018 0.0253 0.078
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0253 0.1005
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0583 0.1263
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0374 0.1194
Toxoplasma gondii sugar transporter ST2 0.0014 0.0177 0.0267
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0374 0.0566
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0007 0.0008 0.0025
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0165 0.3715 0.3602
Plasmodium vivax hexose transporter 0.0102 0.2232 0.2092
Brugia malayi hypothetical protein 0.001 0.0076 0.0164
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0382

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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