Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0945 | 0.0895 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0079 | 0.1137 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0076 | 0.1079 | 0.103 |
Schistosoma mansoni | tyrosine kinase | 0.0251 | 0.4884 | 0.4962 |
Schistosoma mansoni | Protein aveugle | 0.0029 | 0.0054 | 0.0006 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0052 | 0.0544 | 0.0492 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0075 | 0.0052 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0034 | 0.016 | 0.0273 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0054 | 0.0006 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0991 | 0.2434 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0079 | 0.1137 | 0.2801 |
Schistosoma mansoni | spingomyelin synthetase-related | 0.0029 | 0.0054 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0311 | 0.0258 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0079 | 0.1137 | 1 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0207 | 0.3918 | 1 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0207 | 0.3918 | 1 |
Giardia lamblia | CEGP1 protein | 0.0041 | 0.0311 | 0.0764 |
Echinococcus multilocularis | methionine synthase reductase | 0.0128 | 0.2195 | 0.2198 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0031 | 0.0098 | 0.0044 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.0166 | 0.303 | 0.3059 |
Schistosoma mansoni | tyrosine kinase | 0.0155 | 0.2792 | 0.2815 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0054 | 0.0006 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0063 | 0.0785 | 0.075 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 1 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0052 | 0.0544 | 0.1277 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0207 | 0.3918 | 0.5537 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0347 | 0.0294 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0079 | 0.1137 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0063 | 0.0785 | 0.0755 |
Schistosoma mansoni | lip-related protein (liprin) alpha | 0.0029 | 0.0054 | 0.0006 |
Loa Loa (eye worm) | glutathione reductase | 0.0052 | 0.0544 | 0.0492 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0118 | 0.1992 | 0.2486 |
Schistosoma mansoni | tyrosine kinase | 0.0155 | 0.2792 | 0.2815 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.0166 | 0.303 | 0.7638 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0311 | 0.0444 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0034 | 0.016 | 0.0273 |
Entamoeba histolytica | cysteine-rich surface protein, putative | 0.0041 | 0.0311 | 0.1544 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0131 | 0.2279 | 0.2918 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0102 | 0.1649 | 0.5289 |
Mycobacterium leprae | 3-oxoacyl-[acyl-carrier-protein] synthase 1 KasA (BETA-KETOACYL-ACP SYNTHASE) (KAS I) | 0.0141 | 0.2482 | 1 |
Brugia malayi | FAD binding domain containing protein | 0.0128 | 0.2195 | 0.2152 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0031 | 0.0098 | 0.0045 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0118 | 0.1992 | 0.2486 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0072 | 0.0991 | 0.2213 |
Plasmodium falciparum | cysteine repeat modular protein 4 | 0.0041 | 0.0311 | 0.0308 |
Brugia malayi | Protein kinase domain containing protein | 0.0155 | 0.2792 | 0.2753 |
Echinococcus multilocularis | dna polymerase eta | 0.007 | 0.0945 | 0.0914 |
Toxoplasma gondii | GCC2 and GCC3 domain-containing protein | 0.0041 | 0.0311 | 0.0725 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.0348 | 0.6996 | 1 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0041 | 0.0309 | 0.0719 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.0348 | 0.6996 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0311 | 0.0269 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0207 | 0.3918 | 1 |
Plasmodium vivax | cysteine repeat modular protein 3, putative | 0.0041 | 0.0311 | 0.0444 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0042 | 0.0336 | 0.0295 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.1079 | 0.2652 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier protein] synthase 2 KasB (beta-ketoacyl-ACP synthase) (KAS I) | 0.0141 | 0.2482 | 0.3223 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Brugia malayi | flavodoxin family protein | 0.0079 | 0.1137 | 0.1088 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0311 | 0.0258 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0063 | 0.0785 | 0.0734 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0118 | 0.1992 | 0.6032 |
Trichomonas vaginalis | chromobox protein, putative | 0.0076 | 0.1079 | 0.2652 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0063 | 0.0785 | 0.075 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0183 | 0.3406 | 0.8675 |
Plasmodium vivax | cysteine repeat modular protein 2, putative | 0.0041 | 0.0311 | 0.0444 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0079 | 0.1137 | 0.1506 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0476 | 0.9794 | 0.9793 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0207 | 0.3918 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0031 | 0.0098 | 0.0044 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.0418 | 0.0941 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0991 | 0.0967 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.004 | 0.0295 | 0.0247 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0347 | 0.0758 |
Entamoeba histolytica | protein kinase, putative | 0.0041 | 0.0311 | 0.1544 |
Brugia malayi | chromobox protein homolog 3 | 0.0043 | 0.0347 | 0.0294 |
Schistosoma mansoni | lar interacting protein (lip)-related protein | 0.0029 | 0.0054 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0145 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0062 | 0.0008 |
Echinococcus granulosus | dna polymerase kappa | 0.0042 | 0.0336 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0347 | 0.0294 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0042 | 0.0336 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.0374 | 0.7571 | 0.7558 |
Toxoplasma gondii | 3-oxoacyl-acyl-carrier protein synthase I/II, putative | 0.0166 | 0.303 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0991 | 0.0962 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0207 | 0.3918 | 0.56 |
Echinococcus granulosus | dna polymerase eta | 0.007 | 0.0945 | 0.0914 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0042 | 0.0336 | 0.0289 |
Leishmania major | p450 reductase, putative | 0.0207 | 0.3918 | 1 |
Echinococcus multilocularis | sodium channel protein | 0.004 | 0.0295 | 0.0247 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0046 | 0.0418 | 0.0366 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0166 | 0.303 | 0.7702 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0029 | 0.0054 | 0.0006 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0031 | 0.0098 | 0.013 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0042 | 0.0335 | 0.0344 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0207 | 0.3918 | 0.3884 |
Echinococcus granulosus | insulin receptor | 0.0155 | 0.2792 | 0.2811 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0166 | 0.303 | 0.4045 |
Schistosoma mansoni | tyrosine kinase | 0.0251 | 0.4884 | 0.4962 |
Toxoplasma gondii | endonuclease IV APN | 0.0084 | 0.1246 | 0.3915 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0042 | 0.0336 | 0.0729 |
Echinococcus multilocularis | 0.0146 | 0.2599 | 0.2612 | |
Echinococcus multilocularis | ephrin type A receptor 4 A | 0.0422 | 0.8617 | 0.8792 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 1 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0258 | 0.5033 | 0.5111 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier protein] synthase 1 KasA (beta-ketoacyl-ACP synthase) (KAS I) | 0.0141 | 0.2482 | 0.3223 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0034 | 0.016 | 0.0284 |
Schistosoma mansoni | ephrin receptor | 0.0381 | 0.772 | 0.7872 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0311 | 0.1544 |
Onchocerca volvulus | 0.0374 | 0.7571 | 0.7558 | |
Loa Loa (eye worm) | flavodoxin family protein | 0.0079 | 0.1137 | 0.1088 |
Plasmodium falciparum | 3-oxoacyl-acyl-carrier protein synthase I/II | 0.0166 | 0.303 | 0.4251 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.0348 | 0.6996 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.0729 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0079 | 0.1137 | 0.2801 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0207 | 0.3918 | 1 |
Trypanosoma cruzi | p450 reductase, putative | 0.0207 | 0.3918 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0476 | 0.9794 | 1 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0104 | 0.1683 | 0.1677 |
Giardia lamblia | Hypothetical protein | 0.0041 | 0.0311 | 0.0764 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0991 | 0.0962 |
Echinococcus multilocularis | insulin receptor | 0.0155 | 0.2792 | 0.2811 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0045 | 0.0398 | 0.2442 |
Schistosoma mansoni | tyrosine kinase | 0.0251 | 0.4884 | 0.4962 |
Schistosoma mansoni | tyrosine kinase | 0.0258 | 0.5033 | 0.5114 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0079 | 0.1137 | 0.2801 |
Schistosoma mansoni | DNA polymerase eta | 0.007 | 0.0945 | 0.092 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.0166 | 0.303 | 0.3055 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0041 | 0.0311 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0348 | 0.6996 | 0.698 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0207 | 0.3918 | 1 |
Schistosoma mansoni | DNAj-like protein | 0.0029 | 0.0054 | 0.0006 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0042 | 0.0327 | 0.028 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0042 | 0.0336 | 0.0289 |
Echinococcus granulosus | ephrin type A receptor 4 A | 0.0422 | 0.8617 | 0.8792 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0052 | 0.0544 | 0.0777 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0072 | 0.0991 | 0.0942 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0041 | 0.0309 | 0.0659 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0031 | 0.0098 | 0.0000000010628 |
Mycobacterium tuberculosis | Probable reductase | 0.0118 | 0.1992 | 0.2486 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0041 | 0.0311 | 0.0258 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.0166 | 0.303 | 0.2992 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0155 | 0.2792 | 0.2753 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0131 | 0.2279 | 0.2918 |
Leishmania major | DNA polymerase eta, putative | 0.0041 | 0.0309 | 0.0397 |
Brugia malayi | Thioredoxin reductase | 0.0052 | 0.0544 | 0.0492 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0045 | 0.0397 | 0.0888 |
Onchocerca volvulus | 0.0041 | 0.0311 | 0.0258 | |
Echinococcus granulosus | epidermal growth factor receptor | 0.0476 | 0.9794 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0476 | 0.9794 | 1 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0079 | 0.1137 | 1 |
Brugia malayi | glutathione reductase | 0.0052 | 0.0544 | 0.0492 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0348 | 0.6996 | 1 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0102 | 0.1649 | 0.1642 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.0166 | 0.303 | 0.3055 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.1079 | 0.1052 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0098 | 0.0044 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0348 | 0.6996 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0075 | 0.0052 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.0729 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0042 | 0.0327 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.3918 | 0.3884 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.1079 | 0.1057 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0063 | 0.0785 | 0.0674 |
Plasmodium falciparum | cysteine repeat modular protein 2 | 0.0041 | 0.0311 | 0.0308 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0207 | 0.3918 | 0.3967 |
Plasmodium falciparum | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0084 | 0.1246 | 0.1664 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0079 | 0.1137 | 0.2801 |
Mycobacterium leprae | 3-oxoacyl-[acyl-carrier-protein] synthase 2 KasB (BETA-KETOACYL-ACP SYNTHASE) (KAS I) | 0.0141 | 0.2482 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0046 | 0.0418 | 0.0941 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0079 | 0.1137 | 0.2801 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0183 | 0.3406 | 0.4868 |
Plasmodium falciparum | thioredoxin reductase | 0.0052 | 0.0544 | 0.0646 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0348 | 0.6996 | 1 |
Echinococcus granulosus | sodium channel protein | 0.004 | 0.0295 | 0.0247 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.0336 | 0.074 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0045 | 0.0398 | 0.2442 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0045 | 0.0397 | 0.0888 |
Schistosoma mansoni | tyrosine kinase | 0.0258 | 0.5033 | 0.5114 |
Chlamydia trachomatis | sulfite reductase | 0.0128 | 0.2195 | 0.1651 |
Giardia lamblia | Hypothetical protein | 0.0183 | 0.3406 | 1 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0207 | 0.3918 | 0.3967 |
Schistosoma mansoni | DNA helicase recq1 | 0.0031 | 0.0098 | 0.0051 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0118 | 0.1992 | 0.2486 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0207 | 0.3918 | 0.397 |
Plasmodium falciparum | conserved protein, unknown function | 0.0041 | 0.0311 | 0.0308 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.004 | 0.0295 | 0.036 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0258 | 0.5033 | 0.5111 |
Plasmodium vivax | hypothetical protein, conserved | 0.0079 | 0.1137 | 0.1625 |
Schistosoma mansoni | Protein aveugle | 0.0029 | 0.0054 | 0.0006 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0042 | 0.0336 | 0.0283 |
Echinococcus granulosus | methionine synthase reductase | 0.0128 | 0.2195 | 0.2198 |
Leishmania major | cytochrome P450 reductase, putative | 0.0183 | 0.3406 | 0.8637 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0118 | 0.1992 | 0.2486 |
Leishmania major | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.0469 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0059 | 0.0693 | 0.0642 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0045 | 0.0398 | 0.2442 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0311 | 0.1544 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0029 | 0.0054 | 0.0006 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0052 | 0.0544 | 0.0502 |
Trypanosoma brucei | Present in the outer mitochondrial membrane proteome 24 | 0.0029 | 0.0054 | 0.0012 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Plasmodium vivax | apurinic/apyrimidinic endonuclease Apn1, putative | 0.0084 | 0.1246 | 0.1781 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0128 | 0.2195 | 0.2152 |
Echinococcus multilocularis | dna polymerase kappa | 0.0042 | 0.0336 | 0.0289 |
Schistosoma mansoni | lozenge | 0.0061 | 0.0742 | 0.0711 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0118 | 0.1992 | 0.2486 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0042 | 0.0336 | 0.0469 |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.1079 | 0.1052 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0079 | 0.1137 | 0.2801 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0207 | 0.3918 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.0336 | 0.074 |
Brugia malayi | flavodoxin family protein | 0.0207 | 0.3918 | 0.3884 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0076 | 0.1079 | 0.103 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0079 | 0.1137 | 0.2801 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative | 0.0166 | 0.303 | 0.4331 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0052 | 0.0544 | 0.0312 |
Onchocerca volvulus | 0.0486 | 1 | 1 | |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.0166 | 0.303 | 0.4045 |
Echinococcus multilocularis | Protein lozenge | 0.0061 | 0.0742 | 0.0706 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0166 | 0.303 | 0.2992 |
Schistosoma mansoni | DNA helicase recq5 | 0.0031 | 0.0098 | 0.0051 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0207 | 0.3918 | 0.3967 |
Echinococcus granulosus | bloom syndrome protein | 0.0045 | 0.0397 | 0.0352 |
Toxoplasma gondii | hypothetical protein | 0.0041 | 0.0311 | 0.0725 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0031 | 0.0098 | 0.0044 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0128 | 0.2195 | 0.2202 |
Schistosoma mansoni | phd finger protein | 0.0029 | 0.0054 | 0.0006 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0031 | 0.0098 | 0.0045 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0031 | 0.0098 | 0.0045 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0207 | 0.3918 | 0.5378 |
Brugia malayi | DNA-(Apurinic or apyrimidinic site) lyase | 0.0084 | 0.1246 | 0.1198 |
Brugia malayi | hypothetical protein | 0.0133 | 0.2323 | 0.2281 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.0336 | 0.074 |
Mycobacterium tuberculosis | Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) | 0.0084 | 0.1246 | 0.1366 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.007 | 0.0945 | 0.2305 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0045 | 0.0397 | 0.0345 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0063 | 0.0785 | 0.0674 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0052 | 0.0544 | 0.0502 |
Plasmodium vivax | protein kinase, putative | 0.0036 | 0.0203 | 0.029 |
Toxoplasma gondii | thioredoxin reductase | 0.0052 | 0.0544 | 0.1521 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0052 | 0.0544 | 0.1267 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0063 | 0.0785 | 0.0674 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0207 | 0.3918 | 1 |
Echinococcus multilocularis | endonuclease reverse transcriptase | 0.0041 | 0.0311 | 0.0263 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.0729 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0991 | 0.0942 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0042 | 0.0336 | 0.0295 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0079 | 0.1137 | 0.1506 |
Echinococcus multilocularis | chromobox protein 1 | 0.0076 | 0.1079 | 0.1052 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0131 | 0.2279 | 0.8359 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0258 | 0.5033 | 0.5111 |
Giardia lamblia | DINP protein human, muc B family | 0.0042 | 0.0336 | 0.0841 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0072 | 0.0991 | 0.8515 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0063 | 0.0785 | 0.1663 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.0166 | 0.303 | 0.7705 |
Plasmodium falciparum | glutathione reductase | 0.0052 | 0.0544 | 0.0646 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.0166 | 0.303 | 0.3103 |
Brugia malayi | ephrin receptor 1 precursor | 0.0183 | 0.3407 | 0.3371 |
Leishmania major | trypanothione reductase | 0.0052 | 0.0544 | 0.1022 |
Chlamydia trachomatis | oxoacyl-ACP synthase III | 0.0348 | 0.6996 | 1 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0207 | 0.3918 | 0.3967 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0183 | 0.3406 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0991 | 0.2425 |
Treponema pallidum | flavodoxin | 0.0079 | 0.1137 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.1246 | 0.1198 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.0729 |
Schistosoma mansoni | chromobox protein | 0.0076 | 0.1079 | 0.1057 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Trypanosoma brucei | SAM domain (Sterile alpha motif), putative | 0.0029 | 0.0054 | 0.0012 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0207 | 0.3918 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.007 | 0.0945 | 0.209 |
Toxoplasma gondii | kringle domain-containing protein | 0.0041 | 0.0311 | 0.0725 |
Echinococcus granulosus | endonuclease reverse transcriptase | 0.0041 | 0.0311 | 0.0263 |
Brugia malayi | FAD binding domain containing protein | 0.0207 | 0.3918 | 0.3884 |
Plasmodium falciparum | cysteine repeat modular protein 3 | 0.0041 | 0.0311 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.3565 | 0.353 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0041 | 0.0311 | 0.1544 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0347 | 0.0758 |
Plasmodium vivax | glutathione reductase, putative | 0.0052 | 0.0544 | 0.0777 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.0336 | 0.074 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0031 | 0.0098 | 0.0045 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0045 | 0.0398 | 0.2442 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.007 | 0.0945 | 0.2314 |
Loa Loa (eye worm) | RecQ helicase | 0.0045 | 0.0397 | 0.0345 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0079 | 0.1137 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0311 | 0.0258 |
Leishmania major | hypothetical protein, conserved | 0.0079 | 0.1137 | 0.2599 |
Echinococcus multilocularis | bloom syndrome protein | 0.0045 | 0.0397 | 0.0352 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0041 | 0.0311 | 0.0258 |
Onchocerca volvulus | 0.0041 | 0.0311 | 0.0258 | |
Echinococcus granulosus | chromobox protein 1 | 0.0076 | 0.1079 | 0.1052 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0991 | 0.2425 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0169 | 0.3099 | 0.3126 |
Mycobacterium ulcerans | endonuclease IV | 0.0084 | 0.1246 | 0.1366 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.0348 | 0.6996 | 1 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0041 | 0.0311 | 0.0444 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0041 | 0.0311 | 0.0258 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.0336 | 0.074 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0169 | 0.3099 | 0.3126 |
Schistosoma mansoni | polyhomeotic | 0.0029 | 0.0054 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0311 | 0.0258 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0042 | 0.0336 | 0.1806 |
Onchocerca volvulus | 0.0034 | 0.0145 | 0.0092 | |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.0166 | 0.303 | 0.7702 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.007 | 0.0945 | 0.0895 |
Loa Loa (eye worm) | runx1 | 0.0061 | 0.0742 | 0.0691 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0042 | 0.0336 | 0.0283 |
Loa Loa (eye worm) | TK/EPH protein kinase | 0.0484 | 0.9956 | 0.9956 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0476 | 0.9794 | 0.9793 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0079 | 0.1137 | 0.2809 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0102 | 0.1649 | 0.5289 |
Entamoeba histolytica | fatty acid elongase, putative | 0.0045 | 0.0398 | 0.2442 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0131 | 0.2279 | 0.2918 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0041 | 0.0311 | 0.0258 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0311 | 0.0444 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Injected dose (functional) | = 1.8 % | Pulmonary levels of tracer copper in rats 2 hr after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.2 % | Kidney levels of tracer copper in rats 5 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.2 % | Kidney levels of tracer copper in rats 2 hr after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.3 % | Myocardial levels of tracer copper in rats 2 hr after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.3 % | Kidney levels of tracer copper in rats 1 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.6 % | Myocardial levels of tracer copper in rats 1 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.7 % | Brain levels of tracer copper in rats 5 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.7 % | Myocardial levels of tracer copper in rats 5 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.8 % | Brain levels of tracer copper in rats 1 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 2.9 % | Brain levels of tracer copper in rats 2 hr after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 4.7 % | Pulmonary levels of tracer copper in rats 1 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 6.5 % | Blood levels of tracer copper in rats 2 hr after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 6.6 % | Blood levels of tracer copper in rats 5 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 6.8 % | Pulmonary levels of tracer copper in rats 5 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 7.3 % | Blood levels of tracer copper in rats 1 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 9.9 % | Liver levels of tracer copper in rats 1 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 12.7 % | Liver levels of tracer copper in rats 5 min after injection into the femoral vein | ChEMBL. | 2342070 |
Injected dose (functional) | = 12.8 % | Liver levels of tracer copper in rats 2 hr after injection into the femoral vein | ChEMBL. | 2342070 |
logP (ADMET) | = 2.65 | Partition coefficient (logP) | ChEMBL. | 2342070 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.