Detailed information for compound 763614

Basic information

Technical information
  • TDR Targets ID: 763614
  • Name: 3-[2-(4-tert-butylphenoxy)-4-oxopyrido[1,2-a] pyrimidin-3-yl]-2-cyano-N-(oxolan-2-ylmethyl) prop-2-enamide
  • MW: 472.536 | Formula: C27H28N4O4
  • H donors: 1 H acceptors: 3 LogP: 3.58 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CC(=Cc1c(Oc2ccc(cc2)C(C)(C)C)nc2n(c1=O)cccc2)C(=O)NCC1CCCO1
  • InChi: 1S/C27H28N4O4/c1-27(2,3)19-9-11-20(12-10-19)35-25-22(26(33)31-13-5-4-8-23(31)30-25)15-18(16-28)24(32)29-17-21-7-6-14-34-21/h4-5,8-13,15,21H,6-7,14,17H2,1-3H3,(H,29,32)/b18-15+
  • InChiKey: IJXRIZMWBQFZIU-OBGWFSINSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-3-[2-(4-tert-butylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(oxolan-2-ylmethyl)prop-2-enamide
  • (E)-3-[2-(4-tert-butylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(tetrahydrofuran-2-ylmethyl)prop-2-enamide
  • 3-[2-(4-tert-butylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(tetrahydrofuran-2-ylmethyl)prop-2-enamide
  • (E)-3-[2-(4-tert-butylphenoxy)-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-2-cyano-N-(2-tetrahydrofuranylmethyl)prop-2-enamide
  • 3-[2-(4-tert-butylphenoxy)-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-2-cyano-N-(2-tetrahydrofuranylmethyl)prop-2-enamide
  • (E)-3-[2-(4-tert-butylphenoxy)-4-keto-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(tetrahydrofurfuryl)acrylamide
  • 3-[2-(4-tert-butylphenoxy)-4-keto-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(tetrahydrofurfuryl)acrylamide
  • (E)-3-[2-(4-tert-butylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(oxolan-2-ylmethyl)prop-2-enamide
  • 3-[2-(4-tert-butylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(oxolan-2-ylmethyl)prop-2-enamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0236 0.0954
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0106 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0638 0.2728
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0082 0.0358
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0082 0.0358
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0015 0.0065
Schistosoma mansoni lysyl-tRNA synthetase 0.0073 0.0441 0.0861
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0098 0.0623 0.1261
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0046 0.0244 0.5545
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Entamoeba histolytica hypothetical protein 0.0073 0.0441 0.6679
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0169 0.2285
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0082 0.186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Echinococcus granulosus calcium dependent protein kinase 0.0094 0.0593 0.12
Echinococcus granulosus lysyl tRNA synthetase 0.0073 0.0441 0.0889
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0105 0.0376
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0173 0.0678
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0358
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0019 0.0085
Schistosoma mansoni protein kinase 0.01 0.0638 0.1265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0082 0.186
Brugia malayi hypothetical protein 0.0046 0.0244 0.1069
Trichomonas vaginalis sugar transport protein, putative 0.0046 0.0244 0.0992
Brugia malayi intermediate filament protein 0.0027 0.0106 0.0462
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Schistosoma mansoni glucose transporter 0.0046 0.0244 0.046
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0115 0.0742 1
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Leishmania major myo-inositol/proton symporter (MIT) 0.0046 0.0244 0.3296
Trichomonas vaginalis sugar transporter, putative 0.0102 0.0647 0.2769
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0082 0.1105
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0173 0.2335
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0269 0.0509
Echinococcus granulosus intermediate filament protein 0.0027 0.0106 0.0206
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.01 0.0639 0.0602
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.01 0.0638 0.279
Mycobacterium ulcerans hypothetical protein 0.0016 0.0028 0.0643
Loa Loa (eye worm) sugar transporter 0.0328 0.2287 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0082 0.0641
Onchocerca volvulus 0.0046 0.0244 0.8706
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0044 0.008
Onchocerca volvulus 0.0049 0.0269 1
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0028 0.0382
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0062 0.0361 0.5587
Mycobacterium ulcerans sugar transporter 0.0046 0.0244 0.5545
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0173 0.2335
Plasmodium falciparum calcium-dependent protein kinase 5 0.01 0.0639 0.0602
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0647 0.2769
Trypanosoma brucei THT1 - hexose transporter, putative 0.0102 0.0647 0.8731
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0098 0.0623 0.1235
Leishmania major hypothetical protein, conserved 0.0016 0.0028 0.0382
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0106 0.0462
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0044 0.008
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Plasmodium vivax sugar transporter, putative 0.0046 0.0244 0.0207
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0115 0.0742 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0623 0.2725
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Onchocerca volvulus 0.0046 0.0244 0.8706
Brugia malayi Sugar transporter family protein 0.0046 0.0244 0.1069
Trichomonas vaginalis glucose transporter, putative 0.0046 0.0244 0.0992
Echinococcus multilocularis General substrate transporter 0.0281 0.1953 0.3972
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0244 0.1069
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0236 0.318
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0173 0.0757
Loa Loa (eye worm) hypothetical protein 0.008 0.049 0.214
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Brugia malayi hypothetical protein 0.0036 0.0171 0.0747
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0044 0.0996
Plasmodium vivax lysine--tRNA ligase, putative 0.0073 0.0441 0.0404
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Toxoplasma gondii transporter, major facilitator family protein 0.0046 0.0244 0.0327
Toxoplasma gondii sugar transporter ST3 0.0046 0.0244 0.0327
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0073 0.0441 0.1858
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0028 0.0382
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0046 0.0244 0.1383
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0082 0.0901
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0046 0.0244 0.0207
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0004
Brugia malayi beta-lactamase 0.0036 0.0173 0.0757
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0236 0.0442
Giardia lamblia Sugar-proton symporter 0.0046 0.0244 0.346
Trichomonas vaginalis sugar transporter, putative 0.0102 0.0647 0.2769
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0044 0.008
Onchocerca volvulus 0.0046 0.0244 0.8706
Trichomonas vaginalis glucose transporter, putative 0.0102 0.0647 0.2769
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0098 0.0623 0.1261
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0115 0.0742 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0171 0.0339
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Onchocerca volvulus 0.0046 0.0244 0.8706
Onchocerca volvulus 0.0046 0.0244 0.8706
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0044 0.0024
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0173 0.0927
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0046 0.0244 1
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0073 0.0441 0.6932
Loa Loa (eye worm) hypothetical protein 0.0049 0.0269 0.1174
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.01 0.0639 0.0602
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0108
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0244 0.1069
Trypanosoma cruzi sugar transporter, putative 0.0046 0.0244 0.3296
Echinococcus multilocularis lamin 0.0027 0.0106 0.0206
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0082 0.0641
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Plasmodium falciparum calcium-dependent protein kinase 3 0.01 0.0639 0.0602
Loa Loa (eye worm) hypothetical protein 0.0098 0.0623 0.2725
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0173 0.0757
Onchocerca volvulus 0.0046 0.0244 0.8706
Trypanosoma brucei glucose transporter 1E 0.0102 0.0647 0.8731
Giardia lamblia Prolyl-tRNA synthetase 0.0098 0.0623 1
Mycobacterium ulcerans beta-lactamase 0.0036 0.0173 0.3928
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0173 0.2433
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0236 0.0472
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0236 0.318
Plasmodium vivax hexose transporter 0.0328 0.2287 0.2258
Leishmania major hypothetical protein, conserved 0.0046 0.0244 0.3296
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0529 0.3752 0.5643
Plasmodium vivax proline--tRNA ligase, putative 0.0115 0.0742 0.0706
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0019 0.003
Mycobacterium tuberculosis Conserved protein 0.0036 0.0173 0.0927
Schistosoma mansoni hypothetical protein 0.0036 0.0171 0.031
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0236 0.318
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0293
Onchocerca volvulus 0.0046 0.0244 0.8706
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0046 0.0244 0.3296
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0173 0.0927
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0098 0.0623 0.2663
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0044 0.01
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.01 0.0639 0.0925
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Trypanosoma cruzi hexose transporter, putative 0.0102 0.0647 0.8731
Schistosoma mansoni glucose transport protein 0.0328 0.2287 0.4637
Schistosoma mansoni protein kinase 0.01 0.0638 0.1265
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Echinococcus multilocularis lamin dm0 0.0027 0.0106 0.0206
Plasmodium falciparum calcium-dependent protein kinase 1 0.01 0.0639 0.0602
Loa Loa (eye worm) hypothetical protein 0.0027 0.0106 0.0462
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.01 0.0639 0.0925
Plasmodium falciparum calcium-dependent protein kinase 4 0.01 0.0639 0.0602
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0082 0.0343
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0173 0.0927
Leishmania major glucose transporter/membrane transporter D2, putative 0.0102 0.0647 0.8731
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0173 0.3928
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0173 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0328 0.2287 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0082 0.1105
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0019 0.0085
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0173 0.0927
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0044 0.0005
Toxoplasma gondii lysine-tRNA ligase 0.0073 0.0441 0.0625
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Onchocerca volvulus 0.0046 0.0244 0.8706
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0236 0.1031
Schistosoma mansoni glucose transport protein 0.0328 0.2287 0.4637
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium tuberculosis Conserved protein 0.0036 0.0173 0.0927
Leishmania major lysyl-tRNA synthetase, putative 0.0073 0.0441 0.5944
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0044 0.0262
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0173 0.0678
Echinococcus granulosus General substrate transporter 0.0281 0.1953 0.3972
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0046 0.0244 0.0489
Echinococcus granulosus Sugar transporter ERD6 protein 0.0046 0.0244 0.0489
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0019 0.003
Trypanosoma cruzi glucose transporter, putative 0.0046 0.0244 0.3296
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0173 0.3928
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0044 0.0192
Onchocerca volvulus 0.0046 0.0244 0.8706
Trypanosoma cruzi hexose transporter, putative 0.0102 0.0647 0.8731
Onchocerca volvulus 0.0036 0.0173 0.4885
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.3288 0.6691
Leishmania major protein kinase, putative 0.01 0.0638 0.8605
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0028 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0105 0.0376
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Plasmodium falciparum protein kinase 7 0.0925 0.6627 0.6614
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0529 0.3752 0.3727
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0044 0.0192
Plasmodium falciparum proline--tRNA ligase 0.0115 0.0742 0.0706
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0082 0.0641
Trypanosoma brucei THT1 - hexose transporter, putative 0.0102 0.0647 0.8731
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0115 0.0742 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Trichomonas vaginalis esterase, putative 0.0036 0.0173 0.0678
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0115 0.0742 1
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Plasmodium falciparum mitogen-activated protein kinase 2 0.0529 0.3752 0.3727
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Chlamydia trachomatis threonine--tRNA ligase 0.0018 0.0044 0.0133
Mycobacterium leprae Probable lipase LipE 0.0036 0.0173 0.2433
Schistosoma mansoni hypothetical protein 0.017 0.1141 0.2292
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Brugia malayi major facilitator superfamily protein 0.0046 0.0244 0.1069
Brugia malayi Sugar transporter family protein 0.0046 0.0244 0.1069
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0173 0.0314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0098 0.0623 0.2725
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0647 0.2769
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0236 0.318
Onchocerca volvulus Putative transporter 0.0046 0.0244 0.8706
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0082 0.186
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0044 0.0192
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Leishmania major glucose transporter, lmgt2 0.0102 0.0647 0.8731
Leishmania major glucose transporter, lmgt3 0.0102 0.0647 0.8731
Echinococcus multilocularis tumor protein p63 0.0337 0.2359 0.4798
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0046 0.0244 0.046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0103 0.0368
Loa Loa (eye worm) hypothetical protein 0.0026 0.0102 0.0446
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Trichomonas vaginalis sugar transporter, putative 0.0102 0.0647 0.2769
Onchocerca volvulus 0.0027 0.0106 0.1266
Entamoeba histolytica protein kinase, putative 0.01 0.0638 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0082 0.186
Schistosoma mansoni intermediate filament proteins 0.0027 0.0106 0.0176
Loa Loa (eye worm) hypothetical protein 0.0073 0.0441 0.1927
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Echinococcus granulosus tumor protein p63 0.0337 0.2359 0.4798
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0082 0.0358
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0073 0.0441 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0015 0.0065
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0098 0.0623 1
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0638 0.1265
Loa Loa (eye worm) hypothetical protein 0.01 0.0638 0.279
Onchocerca volvulus 0.0046 0.0244 0.8706
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0236 0.0954
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0293
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.01 0.0639 0.0925
Giardia lamblia Hexose transporter 0.0046 0.0244 0.346
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0236 0.323
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0173 0.0927
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Plasmodium falciparum calcium-dependent protein kinase 2 0.01 0.0639 0.0602
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0082 0.186
Toxoplasma gondii facilitative glucose transporter GT1 0.0328 0.2287 0.3424
Plasmodium falciparum lysine--tRNA ligase 0.0073 0.0441 0.0404
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0115 0.0742 0.1081
Onchocerca volvulus 0.0046 0.0244 0.8706
Giardia lamblia GTOR 0.0045 0.0236 0.3312
Trypanosoma cruzi hexose transporter, putative 0.0102 0.0647 0.8731
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0062 0.0361 0.2129
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Trichomonas vaginalis glucose transporter, putative 0.0102 0.0647 0.2769
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0236 0.318
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium ulcerans lipase LipD 0.0036 0.0173 0.3928
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0098 0.0623 0.1235
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0173 0.0927
Echinococcus multilocularis lysyl tRNA synthetase 0.0073 0.0441 0.0889
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0044 0.0024
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0106 0.0462
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0171 0.0339
Chlamydia trachomatis proline--tRNA ligase 0.0035 0.0162 0.3071
Echinococcus granulosus lamin 0.0027 0.0106 0.0206
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0236 0.323
Schistosoma mansoni protein kinase 0.01 0.0638 0.1265
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0098 0.0623 0.9752
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0082 0.186
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0064 0.0865
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0073 0.0441 0.5944
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0082 0.0343
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0046 0.0244 0.5545
Loa Loa (eye worm) hypothetical protein 0.0018 0.0044 0.0192
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0236 0.0472
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0293
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) sugar transporter 0.0046 0.0244 0.1069
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.3288 0.6691
Schistosoma mansoni hypothetical protein 0.0328 0.2287 0.4637
Echinococcus granulosus lamin dm0 0.0027 0.0106 0.0206
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Onchocerca volvulus 0.0046 0.0244 0.8706
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0019 0.0261
Plasmodium vivax CDK-related protein kinase 6, putative 0.139 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Schistosoma mansoni lamin 0.0027 0.0106 0.0176
Plasmodium falciparum hexose transporter 0.0328 0.2287 0.2258
Trypanosoma cruzi hexose transporter 0.0102 0.0647 0.8731
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0173 0.0678
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0152 0.0188
Echinococcus granulosus neuropeptide s receptor 0.0465 0.3288 0.6691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Brugia malayi hypothetical protein 0.0046 0.0244 0.1069
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0044 0.005
Brugia malayi hypothetical protein 0.0046 0.0244 0.1069
Brugia malayi major facilitator superfamily protein 0.0046 0.0244 0.1069
Toxoplasma gondii sugar transporter ST1 0.0046 0.0244 0.0327
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0105 0.0376
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Schistosoma mansoni lysyl-tRNA synthetase 0.0073 0.0441 0.0861
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0039 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.004
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium ulcerans hypothetical protein 0.0024 0.0082 0.186
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Leishmania major hypothetical protein, conserved 0.0036 0.0173 0.2335
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0173 0.2335
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0173 0.0344
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0173 0.0927
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0244 0.1069
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0044 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Onchocerca volvulus 0.0036 0.0173 0.4885
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Echinococcus multilocularis microtubule associated protein 2 0.0689 0.4911 1
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0044 0.0996
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0044 0.0192
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0073 0.0441 1
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0169 0.2285
Brugia malayi Cam kinase protein 1 0.01 0.0638 0.279
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0173 0.0135
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0046 0.0244 0.1383
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.01 0.0638 0.1291
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.01 0.0638 0.279
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0173 0.0344
Toxoplasma gondii sugar transporter ST2 0.0046 0.0244 0.0327
Trypanosoma brucei THT1 - hexose transporter, putative 0.0102 0.0647 0.8731
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0082 0.0901
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0129 0.0482
Onchocerca volvulus 0.0046 0.0244 0.8706
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Mycobacterium ulcerans hypothetical protein 0.0036 0.0173 0.3928
Trichomonas vaginalis myo-inositol transporter, putative 0.0046 0.0244 0.0992
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Onchocerca volvulus 0.0027 0.0106 0.1266
Onchocerca volvulus 0.0046 0.0244 0.8706
Chlamydia trachomatis lysine--tRNA ligase 0.0073 0.0441 1
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Echinococcus multilocularis geminin 0.017 0.1141 0.2316
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.01 0.0639 0.0602
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium tuberculosis Conserved protein 0.0036 0.0173 0.0927
Echinococcus granulosus microtubule associated protein 2 0.0689 0.4911 1
Onchocerca volvulus 0.0036 0.0173 0.4885
Trypanosoma cruzi hexose transporter, putative 0.0056 0.0313 0.4223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0328 0.2287 0.4653
Mycobacterium ulcerans integral membrane transport protein 0.0046 0.0244 0.5545
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0028 0.0382
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0044 0.0192
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0638 0.279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0236 0.0954
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0028 0.0382
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0171 0.031
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0044 0.0005
Echinococcus granulosus synaptic vesicle 2 protein 0.0046 0.0244 0.0489
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Treponema pallidum prolyl-tRNA synthetase 0.0035 0.0162 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Giardia lamblia Lysyl-tRNA synthetase 0.0073 0.0441 0.6849
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0098 0.0623 0.2725
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0236 0.1031
Brugia malayi lysyl-tRNA synthetase 0.0073 0.0441 0.1927
Schistosoma mansoni hypothetical protein 0.017 0.1141 0.2292
Leishmania major hypothetical protein, conserved 0.0016 0.0028 0.0382
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.159 1
Leishmania major glucose transporter, lmgt1 0.0102 0.0647 0.8731
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0358
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0244 0.1069
Brugia malayi Sugar transporter family protein 0.0328 0.2287 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0236 0.318
Toxoplasma gondii ABC1 family protein 0.0036 0.0173 0.0219
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.01 0.0638 0.8605
Schistosoma mansoni lamin 0.0027 0.0106 0.0176
Brugia malayi beta-lactamase family protein 0.0036 0.0173 0.0757
Echinococcus multilocularis calcium dependent protein kinase 0.0094 0.0593 0.12
Trypanosoma brucei sugar transporter, putative 0.0046 0.0244 0.3296
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0103 0.0368
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0082 0.1105
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0073 0.0441 0.5944
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Onchocerca volvulus 0.0046 0.0244 0.8706
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0188 0.0744
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0122 0.0451
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0082 0.186
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0035 0.0162 0.3677
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0062 0.0361 0.2129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Trypanosoma cruzi hexose transporter, putative 0.0046 0.0244 0.3296
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Trypanosoma brucei glucose transporter 2A 0.0102 0.0647 0.8731
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.004 0.0203 0.0887
Schistosoma mansoni microtubule-associated protein tau 0.0689 0.4911 1
Entamoeba histolytica protein kinase, putative 0.01 0.0638 1
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.3288 0.6691
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) beta-lactamase 0.0036 0.0173 0.0757
Echinococcus multilocularis synaptic vesicle 2 protein 0.0046 0.0244 0.0489
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Schistosoma mansoni glucose transport protein 0.0328 0.2287 0.4637
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0045 0.0613
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.004
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0244 0.1069
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0064 0.0375 0.157
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0044 0.008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Echinococcus granulosus geminin 0.017 0.1141 0.2316
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0173 0.0314
Toxoplasma gondii protein kinase, putative 0.0925 0.6627 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.01 0.0639 0.0602
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0173 0.0678
Brugia malayi beta-lactamase family protein 0.0036 0.0173 0.0757
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0039 0.0874
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0169 0.2285
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0019 0.0261
Echinococcus multilocularis musashi 0.0027 0.0106 0.0206
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Onchocerca volvulus 0.0046 0.0244 0.8706

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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