Detailed information for compound 763653

Basic information

Technical information
  • TDR Targets ID: 763653
  • Name: 2-cyano-3-[2-(4-ethylphenoxy)-4-oxopyrido[1,2 -a]pyrimidin-3-yl]-N-(oxolan-2-ylmethyl)prop- 2-enamide
  • MW: 444.482 | Formula: C25H24N4O4
  • H donors: 1 H acceptors: 3 LogP: 2.71 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CC(=Cc1c(Oc2ccc(cc2)CC)nc2n(c1=O)cccc2)C(=O)NCC1CCCO1
  • InChi: 1S/C25H24N4O4/c1-2-17-8-10-19(11-9-17)33-24-21(25(31)29-12-4-3-7-22(29)28-24)14-18(15-26)23(30)27-16-20-6-5-13-32-20/h3-4,7-12,14,20H,2,5-6,13,16H2,1H3,(H,27,30)/b18-14+
  • InChiKey: UYCSRENBZKTXJC-NBVRZTHBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (E)-2-cyano-3-[2-(4-ethylphenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]-N-(oxolan-2-ylmethyl)prop-2-enamide
  • 2-cyano-3-[2-(4-ethylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-N-(tetrahydrofuran-2-ylmethyl)prop-2-enamide
  • (E)-2-cyano-3-[2-(4-ethylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-N-(tetrahydrofuran-2-ylmethyl)prop-2-enamide
  • 2-cyano-3-[2-(4-ethylphenoxy)-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-N-(2-tetrahydrofuranylmethyl)prop-2-enamide
  • (E)-2-cyano-3-[2-(4-ethylphenoxy)-4-oxo-3-pyrido[1,2-a]pyrimidinyl]-N-(2-tetrahydrofuranylmethyl)prop-2-enamide
  • 2-cyano-3-[2-(4-ethylphenoxy)-4-keto-pyrido[1,2-a]pyrimidin-3-yl]-N-(tetrahydrofurfuryl)acrylamide
  • (E)-2-cyano-3-[2-(4-ethylphenoxy)-4-keto-pyrido[1,2-a]pyrimidin-3-yl]-N-(tetrahydrofurfuryl)acrylamide
  • 2-cyano-3-[2-(4-ethylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-N-(oxolan-2-ylmethyl)prop-2-enamide
  • (E)-2-cyano-3-[2-(4-ethylphenoxy)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]-N-(oxolan-2-ylmethyl)prop-2-enamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0638 0.279
Brugia malayi glycyl-tRNA synthetase 0.0018 0.0044 0.0192
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0028 0.0382
Mycobacterium ulcerans integral membrane transport protein 0.0046 0.0244 0.5545
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0171 0.031
Echinococcus granulosus synaptic vesicle 2 protein 0.0046 0.0244 0.0489
Plasmodium vivax threonine--tRNA ligase, putative 0.0018 0.0044 0.0005
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0028 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0236 0.0954
Trypanosoma cruzi hexose transporter, putative 0.0056 0.0313 0.4223
Onchocerca volvulus 0.0036 0.0173 0.4885
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0328 0.2287 0.4653
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Echinococcus multilocularis geminin 0.017 0.1141 0.2316
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.01 0.0639 0.0602
Echinococcus granulosus microtubule associated protein 2 0.0689 0.4911 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0173 0.0927
Onchocerca volvulus 0.0046 0.0244 0.8706
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Onchocerca volvulus 0.0027 0.0106 0.1266
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Chlamydia trachomatis lysine--tRNA ligase 0.0073 0.0441 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.0236 0.318
Brugia malayi Sugar transporter family protein 0.0328 0.2287 1
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0244 0.1069
Schistosoma mansoni lamin 0.0027 0.0106 0.0176
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.01 0.0638 0.8605
Toxoplasma gondii ABC1 family protein 0.0036 0.0173 0.0219
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0358
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Schistosoma mansoni hypothetical protein 0.017 0.1141 0.2292
Brugia malayi lysyl-tRNA synthetase 0.0073 0.0441 0.1927
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.0236 0.1031
Leishmania major glucose transporter, lmgt1 0.0102 0.0647 0.8731
Leishmania major hypothetical protein, conserved 0.0016 0.0028 0.0382
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.159 1
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0098 0.0623 0.2725
Giardia lamblia Lysyl-tRNA synthetase 0.0073 0.0441 0.6849
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Treponema pallidum prolyl-tRNA synthetase 0.0035 0.0162 1
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Echinococcus granulosus neuropeptide receptor A26 0.0465 0.3288 0.6691
Schistosoma mansoni glucose transport protein 0.0328 0.2287 0.4637
Echinococcus multilocularis synaptic vesicle 2 protein 0.0046 0.0244 0.0489
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) beta-lactamase 0.0036 0.0173 0.0757
Trypanosoma cruzi hexose transporter, putative 0.0046 0.0244 0.3296
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Entamoeba histolytica protein kinase, putative 0.01 0.0638 1
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.004 0.0203 0.0887
Schistosoma mansoni microtubule-associated protein tau 0.0689 0.4911 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Trypanosoma brucei glucose transporter 2A 0.0102 0.0647 0.8731
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0082 0.186
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0122 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0188 0.0744
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0035 0.0162 0.3677
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0062 0.0361 0.2129
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0082 0.1105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0103 0.0368
Echinococcus multilocularis calcium dependent protein kinase 0.0094 0.0593 0.12
Trypanosoma brucei sugar transporter, putative 0.0046 0.0244 0.3296
Brugia malayi beta-lactamase family protein 0.0036 0.0173 0.0757
Onchocerca volvulus 0.0046 0.0244 0.8706
Leishmania major threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0073 0.0441 0.5944
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0019 0.0261
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0169 0.2285
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0039 0.0874
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Onchocerca volvulus 0.0046 0.0244 0.8706
Echinococcus multilocularis musashi 0.0027 0.0106 0.0206
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0173 0.0678
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0004
Brugia malayi beta-lactamase family protein 0.0036 0.0173 0.0757
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Plasmodium vivax calcium-dependent protein kinase, putative 0.01 0.0639 0.0602
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0173 0.0314
Toxoplasma gondii protein kinase, putative 0.0925 0.6627 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.004
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0064 0.0375 0.157
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0244 0.1069
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0045 0.0613
Echinococcus granulosus geminin 0.017 0.1141 0.2316
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0018 0.0044 0.008
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Plasmodium falciparum lysine--tRNA ligase 0.0073 0.0441 0.0404
Toxoplasma gondii facilitative glucose transporter GT1 0.0328 0.2287 0.3424
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0082 0.186
Giardia lamblia Hexose transporter 0.0046 0.0244 0.346
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.01 0.0639 0.0925
Plasmodium falciparum calcium-dependent protein kinase 2 0.01 0.0639 0.0602
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0173 0.0927
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.0236 0.323
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Loa Loa (eye worm) hypothetical protein 0.01 0.0638 0.279
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0638 0.1265
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0098 0.0623 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0293
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0236 0.0954
Onchocerca volvulus 0.0046 0.0244 0.8706
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0015 0.0065
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0082 0.186
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0073 0.0441 0.5944
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0064 0.0865
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) hypothetical protein 0.0018 0.0044 0.0192
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0046 0.0244 0.5545
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0082 0.0343
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.0236 0.323
Echinococcus granulosus lamin 0.0027 0.0106 0.0206
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0098 0.0623 0.9752
Schistosoma mansoni protein kinase 0.01 0.0638 0.1265
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0173 0.0927
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0098 0.0623 0.1235
Mycobacterium ulcerans lipase LipD 0.0036 0.0173 0.3928
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0171 0.0339
Chlamydia trachomatis proline--tRNA ligase 0.0035 0.0162 0.3071
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0106 0.0462
Echinococcus multilocularis lysyl tRNA synthetase 0.0073 0.0441 0.0889
Toxoplasma gondii glycyl-tRNA synthetase 0.0018 0.0044 0.0024
Trypanosoma cruzi hexose transporter, putative 0.0102 0.0647 0.8731
Giardia lamblia GTOR 0.0045 0.0236 0.3312
Onchocerca volvulus 0.0046 0.0244 0.8706
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0115 0.0742 0.1081
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.0236 0.318
Trichomonas vaginalis glucose transporter, putative 0.0102 0.0647 0.2769
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0062 0.0361 0.2129
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0105 0.0376
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.004
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0039 0.0065
Schistosoma mansoni lysyl-tRNA synthetase 0.0073 0.0441 0.0861
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Echinococcus granulosus neuropeptide s receptor 0.0465 0.3288 0.6691
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0173 0.0678
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0152 0.0188
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Toxoplasma gondii sugar transporter ST1 0.0046 0.0244 0.0327
Brugia malayi major facilitator superfamily protein 0.0046 0.0244 0.1069
Brugia malayi hypothetical protein 0.0046 0.0244 0.1069
Schistosoma mansoni glycyl-tRNA synthetase 0.0018 0.0044 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Brugia malayi hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Plasmodium falciparum hexose transporter 0.0328 0.2287 0.2258
Trypanosoma cruzi hexose transporter 0.0102 0.0647 0.8731
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Schistosoma mansoni lamin 0.0027 0.0106 0.0176
Echinococcus multilocularis neuropeptide receptor A26 0.0465 0.3288 0.6691
Loa Loa (eye worm) sugar transporter 0.0046 0.0244 0.1069
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0293
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.0236 0.0472
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Plasmodium vivax CDK-related protein kinase 6, putative 0.139 1 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0019 0.0261
Onchocerca volvulus 0.0046 0.0244 0.8706
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Echinococcus granulosus lamin dm0 0.0027 0.0106 0.0206
Schistosoma mansoni hypothetical protein 0.0328 0.2287 0.4637
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium ulcerans hypothetical protein 0.0036 0.0173 0.3928
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Onchocerca volvulus 0.0046 0.0244 0.8706
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Trichomonas vaginalis myo-inositol transporter, putative 0.0046 0.0244 0.0992
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0173 0.0135
Brugia malayi Cam kinase protein 1 0.01 0.0638 0.279
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0169 0.2285
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trypanosoma brucei THT1 - hexose transporter, putative 0.0102 0.0647 0.8731
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0082 0.0901
Toxoplasma gondii sugar transporter ST2 0.0046 0.0244 0.0327
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0129 0.0482
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0173 0.0344
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.01 0.0638 0.279
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.01 0.0638 0.1291
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0046 0.0244 0.1383
Echinococcus multilocularis microtubule associated protein 2 0.0689 0.4911 1
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Onchocerca volvulus 0.0036 0.0173 0.4885
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0073 0.0441 1
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0018 0.0044 0.0192
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0018 0.0044 0.0996
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0173 0.0344
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0173 0.2335
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Leishmania major hypothetical protein, conserved 0.0036 0.0173 0.2335
Mycobacterium ulcerans hypothetical protein 0.0024 0.0082 0.186
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Plasmodium falciparum threonine--tRNA ligase 0.0018 0.0044 0.0005
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0244 0.1069
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0173 0.0927
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.0236 0.318
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0046 0.0244 0.3296
Onchocerca volvulus 0.0046 0.0244 0.8706
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0293
Leishmania major hypothetical protein, conserved 0.0046 0.0244 0.3296
Schistosoma mansoni hypothetical protein 0.0036 0.0171 0.031
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0019 0.003
Mycobacterium tuberculosis Conserved protein 0.0036 0.0173 0.0927
Plasmodium vivax proline--tRNA ligase, putative 0.0115 0.0742 0.0706
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0529 0.3752 0.5643
Giardia lamblia Prolyl-tRNA synthetase 0.0098 0.0623 1
Onchocerca volvulus 0.0046 0.0244 0.8706
Trypanosoma brucei glucose transporter 1E 0.0102 0.0647 0.8731
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0173 0.0757
Plasmodium vivax hexose transporter 0.0328 0.2287 0.2258
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.0236 0.0472
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.0236 0.318
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0173 0.2433
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Mycobacterium ulcerans beta-lactamase 0.0036 0.0173 0.3928
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0082 0.0641
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Echinococcus multilocularis lamin 0.0027 0.0106 0.0206
Trypanosoma cruzi sugar transporter, putative 0.0046 0.0244 0.3296
Loa Loa (eye worm) hypothetical protein 0.0098 0.0623 0.2725
Plasmodium falciparum calcium-dependent protein kinase 3 0.01 0.0639 0.0602
Onchocerca volvulus 0.0046 0.0244 0.8706
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0173 0.0927
Toxoplasma gondii lysine-tRNA ligase 0.0073 0.0441 0.0625
Plasmodium vivax glycine--tRNA ligase, putative 0.0018 0.0044 0.0005
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0019 0.0085
Mycobacterium tuberculosis Conserved protein 0.0036 0.0173 0.0927
Schistosoma mansoni glucose transport protein 0.0328 0.2287 0.4637
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.0236 0.1031
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0173 0.0927
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0082 0.0343
Plasmodium falciparum calcium-dependent protein kinase 4 0.01 0.0639 0.0602
Loa Loa (eye worm) hypothetical protein 0.0027 0.0106 0.0462
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.01 0.0639 0.0925
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0082 0.1105
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0173 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0328 0.2287 1
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0173 0.3928
Leishmania major glucose transporter/membrane transporter D2, putative 0.0102 0.0647 0.8731
Schistosoma mansoni protein kinase 0.01 0.0638 0.1265
Echinococcus multilocularis lamin dm0 0.0027 0.0106 0.0206
Plasmodium falciparum calcium-dependent protein kinase 1 0.01 0.0639 0.0602
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0173 0.0927
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Schistosoma mansoni glucose transport protein 0.0328 0.2287 0.4637
Trypanosoma cruzi hexose transporter, putative 0.0102 0.0647 0.8731
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.01 0.0639 0.0925
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0018 0.0044 0.01
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0098 0.0623 0.2663
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Brugia malayi major facilitator superfamily protein 0.0046 0.0244 0.1069
Schistosoma mansoni hypothetical protein 0.017 0.1141 0.2292
Chlamydia trachomatis threonine--tRNA ligase 0.0018 0.0044 0.0133
Mycobacterium leprae Probable lipase LipE 0.0036 0.0173 0.2433
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Plasmodium falciparum mitogen-activated protein kinase 2 0.0529 0.3752 0.3727
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0115 0.0742 1
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0169 0.0661
Brugia malayi Sugar transporter family protein 0.0046 0.0244 0.1069
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0173 0.0314
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0592
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0115 0.0742 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0082 0.0641
Trypanosoma brucei THT1 - hexose transporter, putative 0.0102 0.0647 0.8731
Plasmodium falciparum proline--tRNA ligase 0.0115 0.0742 0.0706
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0018 0.0044 0.0192
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0529 0.3752 0.3727
Plasmodium falciparum protein kinase 7 0.0925 0.6627 0.6614
Trichomonas vaginalis esterase, putative 0.0036 0.0173 0.0678
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Leishmania major protein kinase, putative 0.01 0.0638 0.8605
Echinococcus multilocularis neuropeptide s receptor 0.0465 0.3288 0.6691
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0028 0.0382
Onchocerca volvulus 0.0036 0.0173 0.4885
Trypanosoma cruzi hexose transporter, putative 0.0102 0.0647 0.8731
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0105 0.0376
Echinococcus granulosus Sugar transporter ERD6 protein 0.0046 0.0244 0.0489
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0046 0.0244 0.0489
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0173 0.0678
Echinococcus granulosus General substrate transporter 0.0281 0.1953 0.3972
Leishmania major lysyl-tRNA synthetase, putative 0.0073 0.0441 0.5944
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0018 0.0044 0.0262
Onchocerca volvulus 0.0046 0.0244 0.8706
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0018 0.0044 0.0192
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0173 0.3928
Trypanosoma cruzi glucose transporter, putative 0.0046 0.0244 0.3296
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0019 0.003
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Loa Loa (eye worm) hypothetical protein 0.0073 0.0441 0.1927
Schistosoma mansoni intermediate filament proteins 0.0027 0.0106 0.0176
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0032 0.002
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0073 0.0441 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0082 0.0358
Echinococcus granulosus tumor protein p63 0.0337 0.2359 0.4798
Echinococcus multilocularis solute carrier family 22 0.0046 0.0244 0.0489
Loa Loa (eye worm) hypothetical protein 0.0026 0.0102 0.0446
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0046 0.0244 0.046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0103 0.0368
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0082 0.186
Entamoeba histolytica protein kinase, putative 0.01 0.0638 1
Onchocerca volvulus 0.0027 0.0106 0.1266
Trichomonas vaginalis sugar transporter, putative 0.0102 0.0647 0.2769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0018 0.0044 0.0192
Echinococcus multilocularis tumor protein p63 0.0337 0.2359 0.4798
Leishmania major glucose transporter, lmgt3 0.0102 0.0647 0.8731
Leishmania major glucose transporter, lmgt2 0.0102 0.0647 0.8731
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0098 0.0623 0.2725
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0082 0.186
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Onchocerca volvulus Putative transporter 0.0046 0.0244 0.8706
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.0236 0.318
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0647 0.2769
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0358
Echinococcus granulosus lysyl tRNA synthetase 0.0073 0.0441 0.0889
Echinococcus granulosus calcium dependent protein kinase 0.0094 0.0593 0.12
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0173 0.0678
Loa Loa (eye worm) hypothetical protein 0.0024 0.0082 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0105 0.0376
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0046 0.0244 0.5545
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0169 0.2285
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0082 0.186
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Entamoeba histolytica hypothetical protein 0.0073 0.0441 0.6679
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0015 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0082 0.0358
Schistosoma mansoni lysyl-tRNA synthetase 0.0073 0.0441 0.0861
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0098 0.0623 0.1261
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0106 0.0462
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.01 0.0638 0.1291
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.0236 0.0954
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0082 0.0358
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0638 0.2728
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Onchocerca volvulus 0.0049 0.0269 1
Mycobacterium ulcerans sugar transporter 0.0046 0.0244 0.5545
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0062 0.0361 0.5587
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0016 0.0028 0.0382
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0082 0.0641
Echinococcus granulosus Threonyl tRNA synthetase C 0.0018 0.0044 0.008
Onchocerca volvulus 0.0046 0.0244 0.8706
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0173 0.2335
Plasmodium falciparum calcium-dependent protein kinase 5 0.01 0.0639 0.0602
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.002
Echinococcus granulosus intermediate filament protein 0.0027 0.0106 0.0206
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.01 0.0639 0.0602
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.01 0.0638 0.279
Loa Loa (eye worm) sugar transporter 0.0328 0.2287 1
Mycobacterium ulcerans hypothetical protein 0.0016 0.0028 0.0643
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0115 0.0742 1
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Schistosoma mansoni glucose transporter 0.0046 0.0244 0.046
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0269 0.0509
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0173 0.2335
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Trichomonas vaginalis sugar transporter, putative 0.0102 0.0647 0.2769
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0082 0.1105
Leishmania major myo-inositol/proton symporter (MIT) 0.0046 0.0244 0.3296
Brugia malayi hypothetical protein 0.0046 0.0244 0.1069
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0082 0.186
Schistosoma mansoni protein kinase 0.01 0.0638 0.1265
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0019 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0294
Brugia malayi intermediate filament protein 0.0027 0.0106 0.0462
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Trichomonas vaginalis sugar transport protein, putative 0.0046 0.0244 0.0992
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.0236 0.318
Loa Loa (eye worm) hypothetical protein 0.008 0.049 0.214
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0173 0.0757
Brugia malayi Major Facilitator Superfamily protein 0.0046 0.0244 0.1069
Plasmodium vivax lysine--tRNA ligase, putative 0.0073 0.0441 0.0404
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0018 0.0044 0.0996
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0152 0.0586
Brugia malayi hypothetical protein 0.0036 0.0171 0.0747
Echinococcus multilocularis General substrate transporter 0.0281 0.1953 0.3972
Trichomonas vaginalis glucose transporter, putative 0.0046 0.0244 0.0992
Brugia malayi Sugar transporter family protein 0.0046 0.0244 0.1069
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0019 0.0261
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0106 0.0462
Echinococcus multilocularis glycyl tRNA synthetase 0.0018 0.0044 0.008
Echinococcus granulosus solute carrier family 22 0.0046 0.0244 0.0489
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0244 0.0992
Leishmania major hypothetical protein, conserved 0.0016 0.0028 0.0382
Onchocerca volvulus 0.0046 0.0244 0.8706
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Loa Loa (eye worm) hypothetical protein 0.0098 0.0623 0.2725
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0115 0.0742 1
Plasmodium vivax sugar transporter, putative 0.0046 0.0244 0.0207
Entamoeba histolytica hypothetical protein 0.0036 0.0171 0.2137
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Trypanosoma brucei THT1 - hexose transporter, putative 0.0102 0.0647 0.8731
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.0647 0.2769
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0098 0.0623 0.1235
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.01 0.0639 0.0602
Loa Loa (eye worm) hypothetical protein 0.0049 0.0269 0.1174
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0073 0.0441 0.6932
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0046 0.0244 1
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0018 0.0044 0.0024
Onchocerca volvulus 0.0046 0.0244 0.8706
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0173 0.0927
Onchocerca volvulus 0.0046 0.0244 0.8706
Loa Loa (eye worm) major facilitator superfamily transporter 0.0046 0.0244 0.1069
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0018 0.0044 0.0108
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Loa Loa (eye worm) hypothetical protein 0.0036 0.0173 0.0757
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0098 0.0623 0.1261
Trichomonas vaginalis glucose transporter, putative 0.0102 0.0647 0.2769
Onchocerca volvulus 0.0046 0.0244 0.8706
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0328 0.2287 0.4653
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0171 0.0339
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0115 0.0742 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.0236 0.0442
Brugia malayi beta-lactamase 0.0036 0.0173 0.0757
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0046 0.0244 0.0207
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0082 0.0901
Loa Loa (eye worm) hypothetical protein 0.0018 0.0039 0.0168
Loa Loa (eye worm) hypothetical protein 0.0046 0.0244 0.1069
Giardia lamblia Sugar-proton symporter 0.0046 0.0244 0.346
Trichomonas vaginalis sugar transporter, putative 0.0102 0.0647 0.2769
Echinococcus granulosus glycyl tRNA synthetase 0.0018 0.0044 0.008
Toxoplasma gondii transporter, major facilitator family protein 0.0046 0.0244 0.0327
Schistosoma mansoni sugar transporter 0.0046 0.0244 0.046
Trypanosoma brucei glucose transporter, putative 0.0102 0.0647 0.8731
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0028 0.004
Trichomonas vaginalis sugar transporter, putative 0.0046 0.0244 0.0992
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0028 0.0382
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0046 0.0244 0.1383
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0073 0.0441 0.1858
Toxoplasma gondii sugar transporter ST3 0.0046 0.0244 0.0327

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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