Detailed information for compound 784959

Basic information

Technical information
  • TDR Targets ID: 784959
  • Name: 2-(2-bromo-4-chlorophenoxy)-N-[(5-nitrofuran- 2-yl)methylideneamino]acetamide
  • MW: 402.585 | Formula: C13H9BrClN3O5
  • H donors: 1 H acceptors: 3 LogP: 3.75 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(COc1ccc(cc1Br)Cl)N/N=C/c1ccc(o1)[N+](=O)[O-]
  • InChi: 1S/C13H9BrClN3O5/c14-10-5-8(15)1-3-11(10)22-7-12(19)17-16-6-9-2-4-13(23-9)18(20)21/h1-6H,7H2,(H,17,19)/b16-6+
  • InChiKey: ACMQVARYPOWIGM-OMCISZLKSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-bromo-4-chloro-phenoxy)-N-[(5-nitro-2-furyl)methyleneamino]acetamide
  • 2-(2-bromo-4-chlorophenoxy)-N-[(5-nitro-2-furyl)methyleneamino]acetamide
  • 2-(2-bromo-4-chloro-phenoxy)-N-[(5-nitrofuran-2-yl)methylideneamino]ethanamide
  • A0956/0044646

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0156 0.041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0156 0.0125
Plasmodium vivax CDK-related protein kinase 6, putative 0.043 1 1
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.036 0.0287
Loa Loa (eye worm) hypothetical protein 0.0025 0.0206 0.0951
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.003 0.0344 0.0371
Schistosoma mansoni transient receptor potential channel 4 0.0106 0.2169 0.5704
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.3375 1
Brugia malayi Bromodomain containing protein 0.0082 0.1588 0.7461
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.003 0.0344 0.0819
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Giardia lamblia Prolyl-tRNA synthetase 0.003 0.0344 0.0371
Echinococcus multilocularis zinc finger protein 0.0021 0.0126 0.0331
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0059 0.0156
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0075 0.0346
Echinococcus granulosus zinc finger protein 0.0021 0.0126 0.0331
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.054 0.142
Loa Loa (eye worm) hypothetical protein 0.0032 0.0378 0.1745
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0204 0.0537
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0154 0.0709
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.003 0.0344 0.1617
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0369 0.7859
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0369 0.7859
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0156 0.0245
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.036 0.0287
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.1184 0.3113
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0359 0.1656
Schistosoma mansoni zinc finger protein 0.0021 0.0126 0.0331
Loa Loa (eye worm) hypothetical protein 0.0077 0.1475 0.6798
Loa Loa (eye worm) hypothetical protein 0.0051 0.0843 0.3888
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.064 0.7695
Echinococcus multilocularis geminin 0.0174 0.3804 1
Schistosoma mansoni protein kinase 0.0031 0.0359 0.0944
Entamoeba histolytica hypothetical protein 0.0023 0.0156 0.0112
Brugia malayi chromobox protein homolog 3 0.0043 0.064 0.3006
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0313 0.0823
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0718 1
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.068 0.1787
Loa Loa (eye worm) hypothetical protein 0.0036 0.0476 0.2196
Schistosoma mansoni protein kinase 0.0031 0.0359 0.0944
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0156 0.0733
Leishmania major glucose transporter, lmgt2 0.0031 0.0369 0.7859
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0843 0.3964
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.064 0.0779
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0313 0.0823
Echinococcus granulosus transient receptor potential gamma protein 0.0106 0.2169 0.5704
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0378 0.0306
Schistosoma mansoni transient receptor potential channel 0.0106 0.2169 0.5704
Plasmodium vivax hexose transporter 0.0101 0.2058 0.1998
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Leishmania major glucose transporter/membrane transporter D2, putative 0.0031 0.0369 0.7859
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0369 0.7859
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Brugia malayi Cam kinase protein 1 0.0031 0.0359 0.1688
Echinococcus multilocularis chromobox protein 1 0.0076 0.1447 0.3804
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0156 0.041
Plasmodium falciparum proline--tRNA ligase 0.0035 0.0466 0.0394
Schistosoma mansoni protein kinase 0.0031 0.0359 0.0944
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0369 0.0406
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0466 1
Echinococcus granulosus jumonji domain containing protein 0.0044 0.068 0.1787
Schistosoma mansoni chromobox protein 0.0076 0.1447 0.3804
Onchocerca volvulus 0.0033 0.0417 0.1137
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.036 0.0441
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0369 0.7859
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0156 0.0082
Echinococcus granulosus peregrin 0.0034 0.0441 0.1159
Loa Loa (eye worm) hypothetical protein 0.003 0.0344 0.1586
Leishmania major protein kinase, putative 0.0031 0.0359 0.7647
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0378 0.0995
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0204 0.0537
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0164 0.3565 0.541
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.003 0.0344 0.0905
Trypanosoma brucei THT1 - hexose transporter, putative 0.0031 0.0369 0.7859
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0359 0.0944
Schistosoma mansoni hypothetical protein 0.0017 0.0013 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.064 0.0779
Schistosoma mansoni transient receptor potential channel 0.007 0.1303 0.3425
Echinococcus multilocularis transient receptor potential gamma protein 0.0106 0.2169 0.5704
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.7318 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.2169 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.036 0.0287
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.036 0.0441
Entamoeba histolytica protein kinase, putative 0.0031 0.0359 0.0392
Trypanosoma cruzi hexose transporter 0.0031 0.0369 0.7859
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0059 0.0156
Plasmodium falciparum hexose transporter 0.0101 0.2058 0.1998
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0843 0.3888
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Schistosoma mansoni bromodomain containing protein 0.0069 0.1279 0.3361
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0369 0.0406
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0025 0.0255
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0369 0.0406
Schistosoma mansoni transient receptor potential channel 0.007 0.1303 0.3425
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0059 0.0156
Brugia malayi PHD-finger family protein 0.0032 0.0378 0.1779
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0344 0.0905
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.2058 0.2737
Loa Loa (eye worm) hypothetical protein 0.0047 0.0734 0.3385
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0101 0.2058 0.541
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0369 0.0406
Echinococcus granulosus geminin 0.0174 0.3804 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.1197 0.5518
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0204 0.0537
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0453 0.2129
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0378 0.047
Brugia malayi Sugar transporter family protein 0.0101 0.2058 0.967
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0378 0.1745
Echinococcus multilocularis chromobox protein 1 0.0076 0.1447 0.3804
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Leishmania major glucose transporter, lmgt1 0.0031 0.0369 0.7859
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0359 0.1656
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.003 0.0344 0.0371
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0104 0.2128 0.5594
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0075 0.137
Loa Loa (eye worm) hypothetical protein 0.0043 0.064 0.2948
Echinococcus granulosus short transient receptor potential channel 6 0.007 0.1303 0.3425
Entamoeba histolytica protein kinase, putative 0.0031 0.0359 0.0392
Echinococcus granulosus chromobox protein 1 0.0076 0.1447 0.3804
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0466 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0156 0.041
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Schistosoma mansoni glucose transport protein 0.0101 0.2058 0.541
Loa Loa (eye worm) hypothetical protein 0.0035 0.0453 0.2088
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0075 0.0197
Echinococcus multilocularis transient receptor potential ion channel A 0.0102 0.2084 0.5479
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0156 0.041
Loa Loa (eye worm) bromodomain containing protein 0.0019 0.0076 0.0348
Brugia malayi Bromodomain containing protein 0.0034 0.0441 0.2072
Schistosoma mansoni ap endonuclease 0.0019 0.0075 0.0197
Loa Loa (eye worm) hypothetical protein 0.0033 0.0417 0.1922
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0059 0.0156
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0075 0.0197
Schistosoma mansoni hypothetical protein 0.0101 0.2058 0.541
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Giardia lamblia PHD finger protein 15 0.0032 0.0378 0.0419
Schistosoma mansoni ap endonuclease 0.0019 0.0075 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0339 0.0364
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0156 0.0082
Schistosoma mansoni jumonji domain containing protein 0.0083 0.161 0.4234
Echinococcus multilocularis General substrate transporter 0.0087 0.1713 0.4505
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0466 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Trypanosoma brucei glucose transporter 1E 0.0031 0.0369 0.7859
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.3375 1
Loa Loa (eye worm) sugar transporter 0.0101 0.2058 0.9485
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0843 0.3964
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0156 0.3158
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0369 0.0406
Plasmodium falciparum phd finger protein, putative 0.0032 0.0378 0.0306
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0075 0.5
Loa Loa (eye worm) hypothetical protein 0.0031 0.0359 0.1656
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.036 0.0441
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0339 0.0364
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0557 0.1465
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Loa Loa (eye worm) hypothetical protein 0.0042 0.0622 0.2865
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0369 0.0406
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0035 0.0466 1
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0156 0.0112
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0562 0.1477
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0075 0.137
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0378 0.047
Echinococcus multilocularis peregrin 0.0034 0.0441 0.1159
Schistosoma mansoni hypothetical protein 0.0032 0.0378 0.0995
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0075 0.0353
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0591 0.1553
Trypanosoma brucei glucose transporter 2A 0.0031 0.0369 0.7859
Brugia malayi PHD-finger family protein 0.0027 0.0267 0.1253
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.036 0.0287
Toxoplasma gondii facilitative glucose transporter GT1 0.0101 0.2058 0.3073
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0059 0.0156
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Trichomonas vaginalis chromobox protein, putative 0.0076 0.1447 0.1894
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0059 0.0156
Loa Loa (eye worm) hypothetical protein 0.0055 0.0928 0.4277
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0718 0.0887
Schistosoma mansoni hypothetical protein 0.0174 0.3804 1
Leishmania major glucose transporter, lmgt3 0.0031 0.0369 0.7859
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0156 0.5
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.036 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0369 0.0406
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0156 0.3158
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0359 0.0944
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0557 0.1465
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0156 0.0245
Echinococcus granulosus transient receptor potential ion channel A 0.0102 0.2084 0.5479
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0378 0.0995
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.036 0.0287
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0059 0.0156
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.7318 1
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0562 0.2639
Brugia malayi Heterochromatin protein 1 0.0076 0.1447 0.6801
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0059 0.0156
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Echinococcus granulosus General substrate transporter 0.0087 0.1713 0.4505
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.7318 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0344 0.1586
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.003 0.0344 0.1617
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0075 0.137
Schistosoma mansoni glucose transport protein 0.0101 0.2058 0.541
Treponema pallidum fructose-bisphosphate aldolase 0.0319 0.7318 1
Plasmodium falciparum mitogen-activated protein kinase 2 0.0164 0.3565 0.3517
Trichomonas vaginalis chromobox protein, putative 0.0076 0.1447 0.1894
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Loa Loa (eye worm) hypothetical protein 0.0019 0.0059 0.0274
Schistosoma mansoni hypothetical protein 0.0035 0.0453 0.1191
Schistosoma mansoni hypothetical protein 0.0023 0.0154 0.0404
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0156 0.3158
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0369 0.7859
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.003 0.0344 0.0905
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0359 0.0392
Loa Loa (eye worm) hypothetical protein 0.0067 0.1217 0.5612
Toxoplasma gondii protein kinase, putative 0.0286 0.6526 1
Echinococcus multilocularis short transient receptor potential channel 6 0.007 0.1303 0.3425
Echinococcus granulosus chromobox protein 1 0.0076 0.1447 0.3804
Trypanosoma brucei glucose transporter, putative 0.0031 0.0369 0.7859
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0075 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0591 0.2723
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.1447 0.667
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0156 0.0249
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Echinococcus granulosus short transient receptor potential channel 6 0.007 0.1303 0.3425
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0378 0.0995
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.036 0.0287
Plasmodium falciparum protein kinase 7 0.0286 0.6526 0.65
Loa Loa (eye worm) hypothetical protein 0.0023 0.0156 0.0719
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.036 0.0287
Schistosoma mansoni zinc finger protein 0.0017 0.0013 0.0034
Plasmodium vivax proline--tRNA ligase, putative 0.0035 0.0466 0.0394
Loa Loa (eye worm) hypothetical protein 0.0039 0.0562 0.2589
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0035 0.0466 0.0606
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0359 0.1688
Schistosoma mansoni glucose transport protein 0.0101 0.2058 0.541
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0164 0.3565 0.3517
Schistosoma mansoni hypothetical protein 0.0174 0.3804 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0075 0.137
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0591 0.1553
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0101 0.2058 0.541
Giardia lamblia Fructose-bisphosphate aldolase 0.0319 0.7318 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0089 0.0019
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0359 0.7647
Brugia malayi jmjC domain containing protein 0.0104 0.2128 1
Schistosoma mansoni chromobox protein 0.0076 0.1447 0.3804
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.1184 0.3113
Brugia malayi jmjC domain containing protein 0.0041 0.0591 0.2776
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0035 0.0466 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0591 0.1553
Brugia malayi Bromodomain containing protein 0.0042 0.062 0.2912
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0562 0.1477
Loa Loa (eye worm) hypothetical protein 0.0044 0.0684 0.3153
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0718 0.0887
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.3375 1
Echinococcus multilocularis short transient receptor potential channel 6 0.007 0.1303 0.3425
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0359 0.0944
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0156 0.0112
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.036 0.0287
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.003 0.0344 0.0905
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0104 0.2128 0.5594

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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