Detailed information for compound 864313

Basic information

Technical information
  • TDR Targets ID: 864313
  • Name: N'-[(4-chlorophenyl)methyl]-N,N-diethylpropan e-1,3-diamine
  • MW: 254.799 | Formula: C14H23ClN2
  • H donors: 1 H acceptors: 0 LogP: 3.05 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCCNCc1ccc(cc1)Cl)CC
  • InChi: 1S/C14H23ClN2/c1-3-17(4-2)11-5-10-16-12-13-6-8-14(15)9-7-13/h6-9,16H,3-5,10-12H2,1-2H3
  • InChiKey: FTIYRWFCGLICAC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N'-[(4-chlorophenyl)methyl]-N,N-diethyl-propane-1,3-diamine
  • 3-[(4-chlorobenzyl)amino]propyl-diethyl-amine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0043 0.0035 0.0027
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0071
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Brugia malayi Stress-activated protein kinase jnk-1 0.0141 0.0162 0.1377
Schistosoma mansoni carbonic anhydrase 0.0325 0.0402 0.0973
Echinococcus multilocularis survival motor neuron protein 1 0.0152 0.0176 0.1497
Schistosoma mansoni survival motor neuron protein 0.0031 0.0019 0.0045
Onchocerca volvulus 0.0023 0.0009 0.0051
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0205 0.0246 0.0238
Brugia malayi hypothetical protein 0.0152 0.0176 0.1495
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0071
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Onchocerca volvulus 0.0023 0.0009 0.0051
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Loa Loa (eye worm) oxidoreductase 0.0043 0.0035 0.0297
Onchocerca volvulus 0.0043 0.0035 0.0211
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Mycobacterium ulcerans transmembrane carbonic anhydrase, SulP 0.0205 0.0246 0.0238
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Echinococcus multilocularis beta LACTamase domain containing family member 0.0023 0.0009 0.0074
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0325 0.0402 0.3419
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0205 0.0246 0.2034
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0919 0.1176 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0001 0.001
Toxoplasma gondii aldose reductase, putative 0.0043 0.0035 0.0674
Trichomonas vaginalis conserved hypothetical protein 0.7694 1 1
Loa Loa (eye worm) aspartyl protease 6 0.0025 0.0012 0.0098
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0919 0.1176 1
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0919 0.1176 0.2845
Mycobacterium ulcerans glutaminase 0.0289 0.0355 0.0347
Mycobacterium tuberculosis Probable oxidoreductase 0.0043 0.0035 0.0033
Onchocerca volvulus 0.0043 0.0035 0.0211
Plasmodium vivax plasmepsin V, putative 0.0025 0.0012 0.0131
Mycobacterium tuberculosis Beta-carbonic anhydrase CanB 0.1633 0.2106 0.2632
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0071
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0919 0.1176 1
Plasmodium vivax aspartyl protease, putative 0.0025 0.0012 0.0131
Schistosoma mansoni glutaminase 0.0289 0.0355 0.086
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0043 0.0035 0.0297
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Brugia malayi Plexin repeat family protein 0.004 0.0031 0.0257
Loa Loa (eye worm) carbonic anhydrase 3 0.0919 0.1176 1
Echinococcus multilocularis plexin a4 0.0047 0.004 0.034
Plasmodium vivax aspartyl protease, putative 0.0025 0.0012 0.0131
Echinococcus granulosus aldehyde reductase 0.0031 0.0019 0.0161
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Plasmodium vivax aspartyl protease, putative 0.0025 0.0012 0.0131
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Onchocerca volvulus 0.0043 0.0035 0.0211
Trypanosoma cruzi aldo-keto reductase 0.0043 0.0035 0.0227
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0098
Trypanosoma brucei aldo-keto reductase, putative 0.0043 0.0035 0.0227
Toxoplasma gondii aspartyl protease ASP1 0.0046 0.0039 0.0759
Mycobacterium ulcerans integral membrane transporter 0.0205 0.0246 0.0238
Brugia malayi ERG2 and Sigma1 receptor like protein 0.023 0.0278 0.2365
Echinococcus granulosus aldo keto reductase 0.0043 0.0035 0.03
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0141 0.0162 0.1379
Schistosoma mansoni cathepsin D (A01 family) 0.0098 0.0107 0.0258
Echinococcus granulosus semaphorin 1A 0.0017 0 0.0003
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Schistosoma mansoni plexin 0.004 0.0031 0.0073
Schistosoma mansoni hypothetical protein 0.0023 0.0009 0.0021
Giardia lamblia Aldose reductase 0.0043 0.0035 0.5
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0025 0.0012 0.0079
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0043 0.0035 0.0027
Trypanosoma brucei C-8 sterol isomerase, putative 0.023 0.0278 0.231
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Schistosoma mansoni carbonic anhydrase-related 0.0325 0.0402 0.0973
Onchocerca volvulus Putative sulfate transporter 0.1289 0.1657 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0039 0.0326
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0919 0.1176 1
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0046 0.0039 0.0759
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Mycobacterium leprae Conserved hypothetical protein 0.0031 0.0019 0.0025
Mycobacterium leprae Probable transmembrane transport protein 0.1489 0.1918 0.4631
Leishmania major C-8 sterol isomerase-like protein 0.023 0.0278 0.0654
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0001 0.001
Trypanosoma cruzi aldo/keto reductase, putative 0.0043 0.0035 0.0227
Loa Loa (eye worm) hypothetical protein 0.004 0.0031 0.0257
Onchocerca volvulus 0.1289 0.1657 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0043 0.0035 0.0027
Schistosoma mansoni aldo-keto reductase 0.0043 0.0035 0.0085
Echinococcus granulosus carbonic anhydrase 0.0325 0.0402 0.3421
Loa Loa (eye worm) oxidoreductase 0.0043 0.0035 0.0297
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0043 0.0035 0.0297
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.1489 0.1918 0.2396
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Echinococcus granulosus beta LACTamase domain containing family member 0.0023 0.0009 0.0074
Echinococcus granulosus hypothetical protein 0.0043 0.0035 0.03
Loa Loa (eye worm) oxidoreductase 0.0043 0.0035 0.0297
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0325 0.0402 0.3419
Trichomonas vaginalis aldo/keto reductase, putative 0.0043 0.0035 0.0027
Mycobacterium ulcerans oxidoreductase 0.0043 0.0035 0.0027
Schistosoma mansoni aldo-keto reductase 0.0043 0.0035 0.0085
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0157 0.0183 0.0442
Onchocerca volvulus 0.004 0.0031 0.0182
Loa Loa (eye worm) oxidoreductase 0.0043 0.0035 0.0297
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0043 0.0035 0.0297
Loa Loa (eye worm) beta-lactamase 0.0023 0.0009 0.0071
Plasmodium falciparum plasmepsin II 0.0046 0.0039 0.0686
Plasmodium falciparum plasmepsin I 0.0046 0.0039 0.0686
Leishmania major aldo-keto reductase-like protein 0.0043 0.0035 0.0064
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Brugia malayi aspartic protease BmAsp-2, identical 0.0025 0.0012 0.0098
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0143 0.0165 0.1397
Brugia malayi hypothetical protein 0.0025 0.0012 0.0098
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0031 0.0019 0.0158
Plasmodium falciparum carbonic anhydrase 0.0325 0.0402 1
Plasmodium vivax aspartyl proteinase, putative 0.0025 0.0012 0.0131
Schistosoma mansoni memapsin-2 (A01 family) 0.0254 0.0309 0.0747
Schistosoma mansoni transient receptor potential channel 0.0017 0.0001 0.0002
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Schistosoma mansoni hypothetical protein 0.016 0.0188 0.0453
Loa Loa (eye worm) glutaminase 0.0289 0.0355 0.3021
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0046 0.0039 0.0326
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0325 0.0402 0.3419
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0043 0.0035 0.0064
Toxoplasma gondii aspartyl protease 0.0025 0.0012 0.0079
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Onchocerca volvulus 0.0043 0.0035 0.0211
Loa Loa (eye worm) hypothetical protein 0.0025 0.0012 0.0098
Echinococcus granulosus survival motor neuron protein 1 0.0152 0.0176 0.1497
Echinococcus multilocularis hypothetical protein 0.0017 0 0.0003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0046 0.0039 0.0093
Onchocerca volvulus 0.0025 0.0012 0.0069
Trichomonas vaginalis aldo/keto reductase, putative 0.0043 0.0035 0.0027
Schistosoma mansoni carbonic anhydrase-related 0.0325 0.0402 0.0973
Plasmodium falciparum plasmepsin VI 0.0046 0.0039 0.0686
Echinococcus granulosus aldo keto reductase 0.0043 0.0035 0.03
Brugia malayi Pepsin A precursor 0.0025 0.0012 0.0098
Schistosoma mansoni vesicular amine transporter 0.0021 0.0006 0.0013
Plasmodium vivax aspartyl proteinase, putative 0.0046 0.0039 0.1258
Echinococcus multilocularis carbonic anhydrase 0.0325 0.0402 0.3421
Echinococcus multilocularis semaphorin 5B 0.0017 0 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0009 0.002
Mycobacterium ulcerans carbonic anhydrase 0.3188 0.4131 0.4126
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0023 0.0009 0.0071
Trypanosoma brucei prostaglandin f synthase 0.0043 0.0035 0.0227
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Trypanosoma brucei Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0205 0.0246 0.2034
Toxoplasma gondii inorganic anion transporter, sulfate permease (SulP) family protein 0.0205 0.0246 0.6033
Trypanosoma cruzi C-8 sterol isomerase, putative 0.023 0.0278 0.231
Chlamydia trachomatis sulfate transporter 0.0205 0.0246 0.5
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0325 0.0402 0.3419
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0919 0.1176 0.2845
Onchocerca volvulus 0.0025 0.0012 0.0069
Loa Loa (eye worm) hypothetical protein 0.023 0.0278 0.2365
Echinococcus granulosus carbonic anhydrase 0.0325 0.0402 0.3421
Plasmodium vivax sulfate transporter, putative 0.0205 0.0246 1
Echinococcus granulosus carbonic anhydrase 0.0325 0.0402 0.3421
Trypanosoma brucei carbonic anhydrase-like protein 0.0919 0.1176 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Leishmania major prostaglandin f synthase, putative 0.0043 0.0035 0.0064
Schistosoma mansoni cathepsin D (A01 family) 0.0098 0.0107 0.0258
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0043 0.0035 0.0297
Echinococcus granulosus semaphorin 5B 0.0017 0 0.0003
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0143 0.0165 0.0398
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0001 0.001
Schistosoma mansoni carbonic anhydrase-related 0.0325 0.0402 0.0973
Schistosoma mansoni plexin 0.0023 0.0009 0.0021
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0071
Onchocerca volvulus 0.0031 0.0019 0.0112
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Brugia malayi olfactory channel protein osm-9 0.0017 0.0001 0.0007
Brugia malayi beta-lactamase family protein 0.0023 0.0009 0.0071
Trichomonas vaginalis aldo/keto reductase, putative 0.0043 0.0035 0.0027
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Loa Loa (eye worm) hypothetical protein 0.0043 0.0035 0.0297
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0001 0.001
Schistosoma mansoni carbonic anhydrase 0.3188 0.4131 1
Trichomonas vaginalis conserved hypothetical protein 0.7694 1 1
Trypanosoma cruzi Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative 0.0205 0.0246 0.2034
Leishmania major carbonic anhydrase family protein, putative 0.3188 0.4131 1
Toxoplasma gondii aspartyl protease ASP3 0.0025 0.0012 0.0079
Onchocerca volvulus 0.0043 0.0035 0.0211
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0023 0.0009 0.002
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0046 0.0039 0.003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0071
Mycobacterium tuberculosis Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) 0.3044 0.3943 0.4939
Echinococcus multilocularis carbonic anhydrase II 0.0919 0.1176 1
Schistosoma mansoni pol-related 0.0043 0.0035 0.0085
Loa Loa (eye worm) hypothetical protein 0.0325 0.0402 0.3419
Mycobacterium leprae CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) 0.3188 0.4131 1
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0325 0.0402 0.3419
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0162 0.0392
Onchocerca volvulus 0.0023 0.0009 0.0051
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0043 0.0035 0.03
Toxoplasma gondii hypothetical protein 0.0325 0.0402 1
Mycobacterium tuberculosis Beta-carbonic anhydrase 0.6139 0.7974 1
Loa Loa (eye worm) hypothetical protein 0.0325 0.0402 0.3419
Leishmania major carbonic anhydrase-like protein 0.0919 0.1176 0.283
Echinococcus multilocularis carbonic anhydrase 0.0325 0.0402 0.3421
Echinococcus multilocularis aldo keto reductase 0.0043 0.0035 0.03
Brugia malayi aspartic protease BmAsp-1, identical 0.0025 0.0012 0.0098
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0001 0.001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0072
Giardia lamblia Aldose reductase 0.0043 0.0035 0.5
Loa Loa (eye worm) hypothetical protein 0.0152 0.0176 0.1495
Echinococcus multilocularis aldo keto reductase 0.0043 0.0035 0.03
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Echinococcus multilocularis aldo keto reductase 0.0043 0.0035 0.03
Loa Loa (eye worm) hypothetical protein 0.0143 0.0165 0.1397
Loa Loa (eye worm) hypothetical protein 0.0118 0.0132 0.1118
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0071
Loa Loa (eye worm) plexin A 0.0047 0.004 0.0337
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0141 0.0162 0.1377
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0023 0.0009 0.0071
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0046 0.0039 0.0328
Echinococcus multilocularis aldehyde reductase 0.0031 0.0019 0.0161
Plasmodium falciparum plasmepsin IV 0.0046 0.0039 0.0686
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0043 0.0035 0.0064
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Loa Loa (eye worm) oxidoreductase 0.0043 0.0035 0.0297
Trichomonas vaginalis glutaminase, putative 0.0289 0.0355 0.0347
Echinococcus granulosus c-Jun N-terminal kinases 0.0141 0.0162 0.1379
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Schistosoma mansoni hypothetical protein 0.0325 0.0402 0.0973
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0147 0.0171 0.0203
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0325 0.0402 0.3419
Plasmodium vivax plasmepsin IV, putative 0.0046 0.0039 0.1258
Loa Loa (eye worm) hypothetical protein 0.0143 0.0165 0.1397
Brugia malayi plexin A 0.0047 0.004 0.0337
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Echinococcus granulosus carbonic anhydrase II 0.0919 0.1176 1
Brugia malayi Eukaryotic aspartyl protease family protein 0.0025 0.0012 0.0098
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0025 0.0012 0.0098
Entamoeba histolytica carbonic anhydrase, putative 0.3188 0.4131 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0025 0.0012 0.0028
Trichomonas vaginalis aldo-keto reductase, putative 0.0043 0.0035 0.0027
Loa Loa (eye worm) glutaminase 2 0.0289 0.0355 0.3021
Brugia malayi hypothetical protein 0.0025 0.0012 0.0098
Echinococcus multilocularis carbonic anhydrase 0.0325 0.0402 0.3421
Brugia malayi beta-lactamase family protein 0.0023 0.0009 0.0071
Echinococcus multilocularis aldo keto reductase 0.0043 0.0035 0.03
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0046 0.0039 0.0328
Brugia malayi glutaminase DH11.1 0.0289 0.0355 0.3021
Trypanosoma brucei RNA helicase, putative 0.016 0.0188 0.1532
Brugia malayi beta-lactamase 0.0023 0.0009 0.0071
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0043 0.0035 0.0064
Onchocerca volvulus 0.0043 0.0035 0.0211
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0919 0.1176 1
Schistosoma mansoni hypothetical protein 0.0031 0.0019 0.0045
Echinococcus granulosus plexin a4 0.0047 0.004 0.034
Loa Loa (eye worm) hypothetical protein 0.0325 0.0402 0.3419
Plasmodium falciparum inorganic anion exchanger, inorganic anion antiporter 0.0205 0.0246 0.6001
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0007
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0043 0.0035 0.03
Echinococcus granulosus aldo keto reductase 0.0043 0.0035 0.03

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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