Detailed information for compound 866530

Basic information

Technical information
  • TDR Targets ID: 866530
  • Name: IDI1_019342
  • MW: 249.392 | Formula: C16H27NO
  • H donors: 1 H acceptors: 1 LogP: 3.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C12CC3CCC(C1)CC(C2)C3)NC(C)(C)C
  • InChi: 1S/C16H27NO/c1-15(2,3)17-14(18)16-8-11-4-5-12(9-16)7-13(6-11)10-16/h11-13H,4-10H2,1-3H3,(H,17,18)
  • InChiKey: GQVAVCMUBAPBDP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ChemDiv3_000024
  • Oprea1_017764

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni aldehyde dehydrogenase 0.0055 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0475 0.0412 0.0412
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.3535 0.3208 0.3208
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0481 0.0418 0.0418
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0478 0.0416 0.0415
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0481 0.0418 0.0418
Loa Loa (eye worm) hypothetical protein 0.072 0.0637 0.0636
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 1.0971 1 1
Loa Loa (eye worm) hypothetical protein 0.0591 0.0519 0.0518
Brugia malayi hypothetical protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0189 0.0152 0.1035
Loa Loa (eye worm) protein-tyrosine phosphatase 1.0971 1 1
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi intermediate filament protein 0.0024 0.0001 0.0001
Echinococcus granulosus tyrosine protein phosphatase non receptor type 1.0971 1 1
Echinococcus multilocularis lamin dm0 0.0024 0.0001 0.0001
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.2414 0.2184 0.2184
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0902 0.0803 0.0802
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0012 0.3995
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.2414 0.2184 0.2184
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0012 0.0012
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0395
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0055 0.0029 0.0029
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0457 0.0396 1
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0457 0.0396 0.0395
Echinococcus granulosus histone lysine methyltransferase setb 0.0024 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0012 0.0011
Echinococcus multilocularis geminin 0.0156 0.0122 0.0121
Echinococcus multilocularis hypothetical protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Brugia malayi hypothetical protein 0.0457 0.0396 0.0395
Echinococcus granulosus intermediate filament protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0001 0.0001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0457 0.0396 0.9596
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0012 0.0012
Onchocerca volvulus 0.0591 0.0519 0.3551
Echinococcus granulosus lamin dm0 0.0024 0.0001 0.0001
Schistosoma mansoni protein tyrosine phosphatase 0.0457 0.0396 0.0395
Schistosoma mansoni hypothetical protein 0.0156 0.0122 0.0121
Onchocerca volvulus 0.0793 0.0703 0.4812
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0475 0.0412 0.0412
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0478 0.0416 0.0415
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.0128 0.0128
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.072 0.0637 0.0636
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0481 0.0418 0.0418
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.046 0.0399 0.0399
Brugia malayi Protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0012 0.0012
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.3531 0.3205 0.3204
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0012 0.0012
Brugia malayi Protein-tyrosine phosphatase 0.046 0.0399 0.0399
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0012 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0088 0.0088
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0001 0.0001
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0481 0.0418 0.0418
Onchocerca volvulus 0.0457 0.0396 0.271
Brugia malayi Matrixin family protein 0.0591 0.0519 0.0518
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0095 0.0065 0.0443
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0396
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0481 0.0418 0.0418
Onchocerca volvulus 4.1 G protein, putative homolog 0.0457 0.0396 0.271
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0396
Schistosoma mansoni lamin 0.0024 0.0001 0.0001
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0396
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0902 0.0803 0.0802
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0457 0.0396 0.0395
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0088 0.0088
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0475 0.0412 1
Schistosoma mansoni protein tyrosine phosphatase 0.0457 0.0396 0.0395
Schistosoma mansoni survival motor neuron protein 0.0093 0.0064 0.0063
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.3531 0.3205 0.3205
Brugia malayi Pre-SET motif family protein 0.0166 0.0131 0.013
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0457 0.0396 1
Brugia malayi Hemopexin family protein 0.0793 0.0703 0.0702
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0037 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.046 0.0399 0.0399
Onchocerca volvulus 0.0457 0.0396 0.271
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Echinococcus granulosus lamin 0.0024 0.0001 0.0001
Onchocerca volvulus Matrilysin homolog 0.0591 0.0519 0.3551
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0037 0.0012 0.0012
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0478 0.0416 0.0415
Schistosoma mansoni lamin 0.0024 0.0001 0.0001
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0457 0.0396 1
Brugia malayi Matrixin family protein 0.0591 0.0519 0.0518
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.046 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.0128 0.0128
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Schistosoma mansoni pcd6 interacting protein-related 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0055 0.0029 0.0427
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0457 0.0396 0.0395
Trichomonas vaginalis set domain proteins, putative 0.0189 0.0152 0.3636
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0012 0.0012
Onchocerca volvulus 0.0024 0.0001 0.0004
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0357 0.0305 0.0304
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0457 0.0396 0.0396
Schistosoma mansoni intermediate filament proteins 0.0024 0.0001 0.0001
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0457 0.0396 0.0395
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0166 0.0131 0.013
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Schistosoma mansoni alpha-glucosidase 0.0141 0.0108 0.0107
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus granulosus protein tyrosine phosphatase n9 0.0457 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0591 0.0519 0.0518
Brugia malayi Protein-tyrosine phosphatase 1 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Leishmania major tyrosine specific protein phosphatase, putative 0.0475 0.0412 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0128 0.0128
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0128 0.0128
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0475 0.0412 0.2821
Mycobacterium leprae PROBABLE HYDROLASE 0.072 0.0637 0.5
Schistosoma mansoni hypothetical protein 0.0793 0.0703 0.0702
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0055 0.0029 0.0028
Loa Loa (eye worm) matrixin family protein 0.1694 0.1527 0.1526
Brugia malayi hypothetical protein 0.0456 0.0395 0.0394
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0475 0.0412 0.0412
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.072 0.0637 1
Onchocerca volvulus 0.0093 0.0064 0.0432
Mycobacterium ulcerans hydrolase 0.072 0.0637 1
Onchocerca volvulus 0.0024 0.0001 0.0004
Brugia malayi MH2 domain containing protein 0.012 0.0088 0.0088
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 1.0971 1 1
Trypanosoma brucei protein tyrosine phosphatase 1 0.0457 0.0396 1
Plasmodium vivax SET domain protein, putative 0.0024 0.0001 0.5
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0457 0.0396 0.0395
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0457 0.0396 0.0395
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0395
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0395
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0395
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0093 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0012 0.0012
Loa Loa (eye worm) protein tyrosine phosphatase 0.0457 0.0396 0.0395
Schistosoma mansoni aldehyde dehydrogenase 0.0055 0.0029 0.0028
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Schistosoma mansoni hypothetical protein 0.0093 0.0064 0.0063
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0396
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0478 0.0416 0.0415
Echinococcus multilocularis lamin 0.0024 0.0001 0.0001
Brugia malayi hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Schistosoma mansoni alpha glucosidase 0.0036 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Echinococcus granulosus geminin 0.0156 0.0122 0.0122
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0457 0.0396 0.0395
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Echinococcus multilocularis musashi 0.0024 0.0001 0.0001
Schistosoma mansoni protein tyrosine phosphatase 0.046 0.0399 0.0399
Echinococcus multilocularis survival motor neuron protein 1 0.0456 0.0395 0.0394
Brugia malayi Matrixin family protein 0.0591 0.0519 0.0518
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0457 0.0396 0.0395
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0475 0.0412 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Toxoplasma gondii aldehyde dehydrogenase 0.0055 0.0029 1
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus granulosus survival motor neuron protein 1 0.0456 0.0395 0.0395
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0475 0.0412 0.0412
Giardia lamblia Protein tyrosine phosphatase 0.0457 0.0396 0.5
Schistosoma mansoni hypothetical protein 0.0156 0.0122 0.0121
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0457 0.0396 0.0395
Schistosoma mansoni alpha-glucosidase 0.0141 0.0108 0.0107
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0396
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0457 0.0396 0.0395
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0012 0.0012
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0001 0.0001
Brugia malayi Matrixin family protein 0.1694 0.1527 0.1526
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0395
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0457 0.0396 0.0396
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0395
Brugia malayi hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0481 0.0418 0.0418
Loa Loa (eye worm) hypothetical protein 0.0457 0.0396 0.0395
Onchocerca volvulus 0.0457 0.0396 0.271
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0478 0.0416 0.0415
Brugia malayi hypothetical protein 0.0457 0.0396 0.0395
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0457 0.0396 0.0395
Echinococcus multilocularis 0.0457 0.0396 0.0395
Onchocerca volvulus Matrix metalloproteinase homolog 0.1311 0.1177 0.8058
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0457 0.0396 0.0396
Onchocerca volvulus 0.0457 0.0396 0.271
Loa Loa (eye worm) matrix metalloproteinase 0.0591 0.0519 0.0518
Onchocerca volvulus 0.0457 0.0396 0.271
Loa Loa (eye worm) matrixin family protein 0.1311 0.1177 0.1176
Brugia malayi Matrixin family protein 0.0591 0.0519 0.0518
Onchocerca volvulus 0.0457 0.0396 0.271
Loa Loa (eye worm) hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0457 0.0396 0.0395
Onchocerca volvulus Matrilysin homolog 0.1622 0.146 1
Trichomonas vaginalis pten, drome, putative 0.0457 0.0396 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0457 0.0396 0.0395
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0457 0.0396 0.0396
Onchocerca volvulus 0.0457 0.0396 0.271
Schistosoma mansoni receptor protein tyrosine phosphatase 0.046 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0456 0.0395 0.0394
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0457 0.0396 0.0396
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0457 0.0396 0.9596
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0012 0.0012

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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