Detailed information for compound 871641

Basic information

Technical information
  • TDR Targets ID: 871641
  • Name: 7-(4-hydroxyphenyl)-5-methyl-N-pyridin-2-yl-1 ,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carbox amide
  • MW: 349.347 | Formula: C17H15N7O2
  • H donors: 3 H acceptors: 6 LogP: 1.52 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)C1C(=C(C)Nc2n1nnn2)C(=O)Nc1ccccn1
  • InChi: 1S/C17H15N7O2/c1-10-14(16(26)20-13-4-2-3-9-18-13)15(11-5-7-12(25)8-6-11)24-17(19-10)21-22-23-24/h2-9,15,25H,1H3,(H,18,20,26)(H,19,21,23)
  • InChiKey: JENMERHCYVQVMC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 7-(4-hydroxyphenyl)-5-methyl-N-(2-pyridyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide
  • 7-(4-hydroxyphenyl)-5-methyl-N-pyridin-2-yl-1,7-dihydro-[1,2,3,4]tetrazolo[1,5-a]pyrimidine-6-carboxamide
  • ChemDiv1_005041
  • Oprea1_435066

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0044 0.026 0.026
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0292 0.0292
Mycobacterium ulcerans hypothetical protein 0.0082 0.0576 0.2542
Brugia malayi G-protein coupled receptor 0.0044 0.026 0.0863
Brugia malayi putative neuropeptide receptor NPR1 0.0044 0.026 0.0863
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0064 0.0064
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0044 0.026 0.026
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0064 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0372 0.2983 0.2981
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0084 0.0362
Loa Loa (eye worm) hypothetical protein 0.0104 0.0754 0.2526
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0064 0.0062
Brugia malayi nuclear receptor NHR-88 0.0021 0.0064 0.0207
Loa Loa (eye worm) glutaminase 2 0.0285 0.2258 0.7571
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Echinococcus multilocularis neuropeptide receptor 0.0044 0.026 0.026
Onchocerca volvulus 0.0044 0.026 0.0984
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0064 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0057 0.0954
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0064 0.0207
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.026 0.026
Echinococcus multilocularis protein patched 0.0045 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0104 0.0754 0.0751
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0082 0.0576 0.2542
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0044 0.026 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0064 0.0207
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0006 0.0071
Brugia malayi beta-lactamase family protein 0.0082 0.0576 0.1924
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0166 0.0164
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0166 0.0166
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0128 0.2197
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0067 0.1118
Schistosoma mansoni neuropeptide f receptor 76f 0.0044 0.026 0.0257
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.0761 0.2546
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0044 0.026 0.026
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0207 0.0481
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.026 0.026
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.2397 0.8036
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.026 0.026
Brugia malayi Tachykinin-like peptides receptor 99D 0.0044 0.026 0.0863
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0012 0.0031
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni ran 0.0021 0.0067 0.0064
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0036 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0064 0.0207
Mycobacterium tuberculosis Probable dehydrogenase 0.0086 0.0608 0.1425
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.0576 0.0574
Onchocerca volvulus 0.0044 0.026 0.0984
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0044 0.026 0.0871
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0036 0.0079
Schistosoma mansoni alpha-1 adrenergic receptor 0.0044 0.026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0091 0.0649 0.2177
Echinococcus multilocularis G protein coupled receptor 139 0.0044 0.026 0.026
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0086 0.0608 0.1425
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0057 0.0954
Schistosoma mansoni hypothetical protein 0.0048 0.0292 0.029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0064 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0166 0.0164
Schistosoma mansoni amine GPCR 0.0044 0.026 0.0257
Echinococcus granulosus Niemann Pick C1 protein 0.0149 0.1133 0.1133
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0064 0.0207
Echinococcus multilocularis g-protein coupled receptor 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1931
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0372 0.2983 0.2983
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0036 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0082 0.0576 0.1931
Brugia malayi Thioredoxin reductase 0.0038 0.0207 0.0686
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0195 0.0853
Echinococcus granulosus neuropeptide receptor A26 0.0496 0.4006 0.4006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0064 0.0207
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0044 0.026 0.026
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.1438 0.482
Mycobacterium tuberculosis Probable lipase LipD 0.0082 0.0576 0.135
Leishmania major importin beta-1 subunit, putative 0.0023 0.0084 0.1424
Echinococcus multilocularis serotonin receptor 0.0044 0.026 0.026
Echinococcus granulosus somatostatin receptor 0.0044 0.026 0.026
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0082 0.0576 0.1924
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus multilocularis expressed conserved protein 0.0098 0.0709 0.0709
Loa Loa (eye worm) hypothetical protein 0.0151 0.1145 0.3837
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0195 0.3356
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.0576 0.2542
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0064 0.0062
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.026 0.026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.026 0.0257
Schistosoma mansoni hypothetical protein 0.0048 0.0292 0.029
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0687 0.1613
Echinococcus granulosus snurportin 1 0.0302 0.2397 0.2397
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0064 0.0207
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0064 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0166 0.0164
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0044 0.026 0.0257
Schistosoma mansoni lamin 0.0026 0.0114 0.0111
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus multilocularis serotonin receptor 0.0044 0.026 0.026
Brugia malayi glutathione reductase 0.0038 0.0207 0.0686
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0064 0.0215
Schistosoma mansoni hypothetical protein 0.0048 0.0292 0.029
Loa Loa (eye worm) hypothetical protein 0.0045 0.0266 0.0892
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0044 0.026 0.026
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.012 0.2051
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.026 0.0257
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0057 0.0057
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0057 0.0055
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0576 0.2542
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0086 0.0608 0.8777
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0057 0.0057
Schistosoma mansoni adenoreceptor 0.0044 0.026 0.0257
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0105 0.0761 0.2552
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0064 0.0064
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1931
Echinococcus multilocularis G-protein coupled receptor, putative 0.0044 0.026 0.026
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Leishmania major trypanothione reductase 0.0038 0.0207 0.3566
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.012 0.2051
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0266 0.0266
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0086 0.0608 0.1425
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus dro:myosuppressin receptor 0.0044 0.026 0.026
Trichomonas vaginalis penicillin-binding protein, putative 0.0082 0.0576 0.2542
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0057 0.0954
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.0761 0.0761
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0067 0.1118
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.1152 0.3855
Onchocerca volvulus 0.0044 0.026 0.0984
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0064 0.0062
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.1438 0.1438
Echinococcus granulosus neuropeptide Y receptor 0.0044 0.026 0.026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0128 0.2197
Echinococcus multilocularis g protein coupled receptor 0.0044 0.026 0.026
Echinococcus granulosus sex peptide receptor 0.0044 0.026 0.026
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0207 0.3566
Mycobacterium tuberculosis Probable esterase LipL 0.0082 0.0576 0.135
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Echinococcus multilocularis fmrfamide receptor 0.0044 0.026 0.026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0082 0.0576 0.0574
Onchocerca volvulus 0.0044 0.026 0.0984
Onchocerca volvulus 0.0044 0.026 0.0984
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.026 0.0257
Toxoplasma gondii ABC1 family protein 0.0082 0.0576 1
Brugia malayi Importin beta-1 subunit 0.0028 0.0128 0.0423
Loa Loa (eye worm) hypothetical protein 0.0091 0.0649 0.2177
Schistosoma mansoni ran 0.0021 0.0067 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0064 0.0215
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.0761 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0067 0.0067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.026 0.026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0064 0.0207
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0576 1
Loa Loa (eye worm) hypothetical protein 0.0152 0.1152 0.386
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.026 0.0257
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0057 0.0954
Schistosoma mansoni importin beta-1 0.0028 0.0128 0.0126
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0044 0.026 0.0863
Echinococcus granulosus intermediate filament protein 0.0026 0.0114 0.0114
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.026 0.0257
Trichomonas vaginalis ferritin, putative 0.0017 0.0036 0.0149
Brugia malayi nuclear hormone receptor 0.0021 0.0064 0.0207
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Echinococcus granulosus ferritin 0.0017 0.0036 0.0036
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.6684 0.6684
Plasmodium vivax hypothetical protein, conserved 0.0082 0.0576 1
Schistosoma mansoni opsin-like receptor 0.0044 0.026 0.0257
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0067 0.0067
Onchocerca volvulus 0.0044 0.026 0.0984
Schistosoma mansoni amine GPCR 0.0044 0.026 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0064 0.0207
Schistosoma mansoni biogenic amine (5HT) receptor 0.0044 0.026 0.0257
Trypanosoma brucei unspecified product 0.002 0.0057 0.0954
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0064 0.0062
Entamoeba histolytica hypothetical protein 0.0023 0.0084 0.0383
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0012 0.0039
Echinococcus multilocularis muscleblind protein 1 0.0151 0.1145 0.1145
Echinococcus multilocularis GPCR, family 2 0.0048 0.0292 0.0292
Brugia malayi Dopamine receptor protein 2 0.0044 0.026 0.0863
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Mycobacterium ulcerans beta-lactamase 0.0082 0.0576 0.2542
Plasmodium falciparum thioredoxin reductase 0.0038 0.0207 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0086 0.0608 0.1425
Toxoplasma gondii thioredoxin reductase 0.0038 0.0207 0.3566
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.026 0.026
Echinococcus granulosus orexin receptor type 2 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.012 0.2051
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.026 0.026
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0064 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Schistosoma mansoni neuropeptide receptor 0.0044 0.026 0.0257
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0195 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0114 0.0381
Schistosoma mansoni inositol monophosphatase 0.0036 0.0195 0.0193
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1931
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0082 0.0576 0.135
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0044 0.026 0.0863
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0372 0.2983 0.2983
Leishmania major hypothetical protein, conserved 0.0082 0.0576 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.026 0.026
Echinococcus multilocularis lamin dm0 0.0026 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni ferritin 0.0017 0.0036 0.0034
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0266 0.0266
Schistosoma mansoni hypothetical protein 0.0044 0.026 0.0257
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0057 0.0954
Plasmodium vivax glutathione reductase, putative 0.0038 0.0207 0.3566
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0044 0.026 0.026
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1931
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0106 0.0775 0.0772
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0064 0.0207
Mycobacterium ulcerans glutaminase 0.0285 0.2258 1
Brugia malayi Dopamine receptor 0.0044 0.026 0.0863
Brugia malayi Serotonin receptor 0.0044 0.026 0.0863
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0195 0.3356
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni neuropeptide receptor 0.0044 0.026 0.0257
Schistosoma mansoni amine GPCR 0.0044 0.026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0044 0.026 0.0257
Echinococcus granulosus g-protein coupled receptor 0.0044 0.026 0.026
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0525 0.4251 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0064 0.0064
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0044 0.026 0.0863
Plasmodium falciparum glutathione reductase 0.0038 0.0207 1
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0292 0.0971
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Brugia malayi Pre-SET motif family protein 0.0033 0.0166 0.0549
Schistosoma mansoni myosin xvIII 0.0044 0.026 0.0257
Brugia malayi glutaminase DH11.1 0.0285 0.2258 0.7569
Echinococcus granulosus G protein coupled receptor 139 0.0044 0.026 0.026
Mycobacterium tuberculosis Conserved protein 0.0082 0.0576 0.135
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0006 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.1438 0.1438
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Onchocerca volvulus 0.0044 0.026 0.0984
Trypanosoma cruzi hypothetical protein, conserved 0.0082 0.0576 1
Brugia malayi hypothetical protein 0.0372 0.2983 1
Echinococcus multilocularis g protein coupled receptor 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0166 0.0556
Loa Loa (eye worm) glutaminase 0.0285 0.2258 0.7571
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0576 0.2542
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.026 0.0871
Brugia malayi Inositol-1 0.0036 0.0195 0.0646
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0057 0.0243
Brugia malayi larval opioid receptor 0.0044 0.026 0.0863
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.012 0.5753
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0064 0.0215
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.1438 0.1436
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0067 0.1118
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus g protein coupled receptor 0.0044 0.026 0.026
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0195 0.3356
Echinococcus granulosus allatostatin A receptor 0.0044 0.026 0.026
Echinococcus granulosus expressed conserved protein 0.0098 0.0709 0.0709
Plasmodium falciparum importin beta, putative 0.0028 0.0128 0.6163
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0084 0.0362
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0036 0.1751
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0044 0.026 0.0863
Schistosoma mansoni hypothetical protein 0.0044 0.026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1931
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0292 0.0292
Echinococcus granulosus alpha 1A adrenergic receptor 0.0044 0.026 0.026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Onchocerca volvulus 0.026 0.2052 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0082 0.0576 0.0576
Echinococcus granulosus importin subunit beta 1 0.0028 0.0128 0.0128
Echinococcus multilocularis dro:myosuppressin receptor 0.0044 0.026 0.026
Onchocerca volvulus 0.0044 0.026 0.0984
Trypanosoma brucei unspecified product 0.0014 0.0006 0.0071
Schistosoma mansoni hypothetical protein 0.0043 0.0253 0.025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0044 0.026 0.0257
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.1438 0.1436
Mycobacterium tuberculosis Probable reductase 0.0086 0.0608 0.1425
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.1438 0.1438
Trichomonas vaginalis esterase, putative 0.0082 0.0576 0.2542
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0195 0.3356
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0166 0.2852
Schistosoma mansoni hypothetical protein 0.0043 0.0253 0.025
Brugia malayi hypothetical protein 0.0018 0.004 0.0126
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.0754 0.252
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0044 0.026 0.026
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.0761 0.0761
Mycobacterium tuberculosis Conserved protein 0.0082 0.0576 0.135
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0044 0.026 0.026
Schistosoma mansoni ferritin 0.0017 0.0036 0.0034
Echinococcus multilocularis dna polymerase eta 0.002 0.0057 0.0057
Schistosoma mansoni DNA polymerase eta 0.002 0.0057 0.0055
Onchocerca volvulus 0.0026 0.0114 0.025
Plasmodium vivax importin-beta 2, putative 0.0028 0.0128 0.2197
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.026 0.026
Entamoeba histolytica Ran family GTPase 0.0021 0.0067 0.0133
Onchocerca volvulus 0.0044 0.026 0.0984
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0044 0.026 0.0257
Schistosoma mansoni amine GPCR 0.0044 0.026 0.0257
Brugia malayi neuropeptide F receptor 0.0044 0.026 0.0863
Echinococcus granulosus dna polymerase kappa 0.002 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus multilocularis neuropeptide receptor A26 0.0496 0.4006 0.4006
Schistosoma mansoni hypothetical protein 0.0043 0.0253 0.025
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0064 0.0064
Schistosoma mansoni ferritin light chain 0.0017 0.0036 0.0034
Leishmania major DNA polymerase eta, putative 0.002 0.0057 0.0954
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Echinococcus granulosus hypothetical protein 0.0044 0.026 0.026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Onchocerca volvulus 0.0044 0.026 0.0984
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0057 0.0243
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0044 0.026 0.0257
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0006 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0266 0.1169
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0687 0.1613
Brugia malayi Melatonin receptor type 1A 0.0044 0.026 0.0863
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Trypanosoma brucei hypothetical protein, conserved 0.0082 0.0576 1
Schistosoma mansoni ferritin 0.0017 0.0036 0.0034
Brugia malayi follicle stimulating hormone receptor 0.0044 0.026 0.0863
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0057 0.0243
Echinococcus multilocularis neuropeptide s receptor 0.0496 0.4006 0.4006
Onchocerca volvulus 0.0044 0.026 0.0984
Loa Loa (eye worm) hypothetical protein 0.0048 0.0292 0.0978
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0064 0.0207
Schistosoma mansoni hypothetical protein 0.0044 0.026 0.0257
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0195 0.0853
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Loa Loa (eye worm) glutathione reductase 0.0038 0.0207 0.0694
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0064 0.0062
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0266 0.0266
Echinococcus granulosus expressed protein 0.0017 0.0036 0.0036
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.179 0.6002
Loa Loa (eye worm) beta-lactamase 0.0082 0.0576 0.1931
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0044 0.026 0.0257
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0057 0.0954
Schistosoma mansoni neuropeptide receptor 0.0044 0.026 0.0257
Schistosoma mansoni apoferritin-2 0.0017 0.0036 0.0034
Echinococcus granulosus neuropeptide s receptor 0.0496 0.4006 0.4006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.026 0.026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0057 0.0192
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0687 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Brugia malayi AKH receptor 0.0044 0.026 0.0863
Onchocerca volvulus 0.0044 0.026 0.0984
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0084 0.0362
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0163 0.1953
Echinococcus granulosus 7TM GPCR rhodopsin 0.0044 0.026 0.026
Echinococcus multilocularis Niemann Pick C1 protein 0.0149 0.1133 0.1133
Echinococcus multilocularis neuropeptide Y receptor 0.0044 0.026 0.026
Brugia malayi G protein-coupled receptor 0.0044 0.026 0.0863
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0044 0.026 0.026
Mycobacterium tuberculosis Probable hydrolase 0.0082 0.0576 0.135
Echinococcus granulosus neuropeptide receptor 0.0044 0.026 0.026
Onchocerca volvulus 0.0044 0.026 0.0984
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0044 0.026 0.026
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0195 0.0853
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0064 0.0207
Brugia malayi Serotonin receptor 0.0044 0.026 0.0863
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0044 0.026 0.026
Onchocerca volvulus 0.0082 0.0576 0.2574
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus g protein coupled receptor 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0028 0.0128 0.0431
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0044 0.026 0.026
Schistosoma mansoni glutaminase 0.0285 0.2258 0.2256
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0067 0.1118
Echinococcus granulosus fmrfamide receptor 0.0044 0.026 0.026
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0044 0.026 0.0871
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0064 0.0064
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.1438 0.1436
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.012 0.5753
Schistosoma mansoni hypothetical protein 0.0044 0.026 0.0257
Onchocerca volvulus 0.0044 0.026 0.0984
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Onchocerca volvulus 0.0044 0.026 0.0984
Echinococcus multilocularis somatostatin receptor 0.0044 0.026 0.026
Echinococcus multilocularis beta LACTamase domain containing family member 0.0082 0.0576 0.0576
Echinococcus multilocularis lamin 0.0026 0.0114 0.0114
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0114 0.0381
Leishmania major GTP-binding protein, putative 0.0021 0.0067 0.1118
Echinococcus granulosus serotonin receptor 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0292 0.0292
Brugia malayi sulfakinin receptor protein 0.0044 0.026 0.0863
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0266 0.0892
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Schistosoma mansoni histamine h1 receptor 0.0044 0.026 0.0257
Schistosoma mansoni lamin 0.0026 0.0114 0.0111
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor 0.0044 0.026 0.026
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0195 0.0853
Schistosoma mansoni ferritin light chain 0.0017 0.0036 0.0034
Onchocerca volvulus 0.0044 0.026 0.0984
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0044 0.026 0.0257
Schistosoma mansoni hypothetical protein 0.1219 1 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Leishmania major DNA polymerase kappa, putative 0.002 0.0057 0.0954
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0067 1
Echinococcus multilocularis geminin 0.1219 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0044 0.026 0.026
Echinococcus multilocularis g protein coupled receptor 0.0044 0.026 0.026
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0044 0.026 0.0863
Echinococcus granulosus lamin dm0 0.0026 0.0114 0.0114
Brugia malayi Pre-SET motif family protein 0.0229 0.179 0.5999
Echinococcus multilocularis protein dispatched 1 0.0051 0.0319 0.0319
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0067 0.0215
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0057 0.0954
Echinococcus multilocularis expressed protein 0.0017 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0302 0.2397 0.2395
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0064 0.0207
Brugia malayi CHE-14 protein 0.0045 0.0266 0.0885
Brugia malayi Muscleblind-like protein 0.0151 0.1145 0.3832
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0086 0.0608 0.1425
Echinococcus multilocularis dna polymerase kappa 0.002 0.0057 0.0057
Mycobacterium leprae Probable lipase LipE 0.0082 0.0576 0.8287
Trichomonas vaginalis D-aminoacylase, putative 0.0082 0.0576 0.2542
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0687 0.1613
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.1152 0.386
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni eyes absent homolog 0.0091 0.0649 0.0647
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0064 0.0207
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0064 0.0207
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0064 0.0064
Brugia malayi putative neuropeptide receptor 0.0044 0.026 0.0863
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus multilocularis neuropeptide receptor 0.0044 0.026 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0064 0.0215
Onchocerca volvulus 0.0082 0.0576 0.2574
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Loa Loa (eye worm) hypothetical protein 0.0027 0.012 0.0402
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0082 0.0576 0.135
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0166 0.0166
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0064 0.0064
Brugia malayi Serine/threonine-protein kinase SULU 0.0372 0.2983 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.1438 0.1438
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0114 0.0373
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0292 0.0978
Brugia malayi RNA, U transporter 1 0.008 0.0561 0.1873
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0211 0.0211
Echinococcus multilocularis neuropeptides capa receptor 0.0044 0.026 0.026
Schistosoma mansoni amine GPCR 0.0044 0.026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0064 0.0215
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Mycobacterium ulcerans lipase LipD 0.0082 0.0576 0.2542
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Schistosoma mansoni neuropeptide F-like receptor 0.0044 0.026 0.0257
Trypanosoma brucei trypanothione reductase 0.0038 0.0207 0.3566
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0067 0.3135
Brugia malayi steroid hormone receptor 0.0021 0.0064 0.0207
Schistosoma mansoni neuropeptide receptor 0.0044 0.026 0.0257
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Loa Loa (eye worm) inositol-1 0.0036 0.0195 0.0653
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0036 0.0079
Loa Loa (eye worm) melatonin receptor type 1A 0.0044 0.026 0.0871
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0195 0.3356
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.1438 0.4816
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0057 0.0243
Brugia malayi ecdysteroid receptor 0.0021 0.0064 0.0207
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0064 0.0207
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0057 0.0129
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0156 0.0156
Onchocerca volvulus 0.0044 0.026 0.0984
Schistosoma mansoni growth hormone secretagogue receptor 0.0044 0.026 0.0257
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0044 0.026 0.0871
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0207 0.3566
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0064 0.0207
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0036 0.0149
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0082 0.0576 0.135
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.012 0.2051
Schistosoma mansoni apoferritin-2 0.0017 0.0036 0.0034
Echinococcus granulosus muscleblind protein 0.0151 0.1145 0.1145
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Brugia malayi Dopamine receptor protein 1 0.0044 0.026 0.0863
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.026 0.0871
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Onchocerca volvulus Neuropeptide F receptor homolog 0.0044 0.026 0.0984
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.012 0.2051
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0128 0.0128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0044 0.026 0.026
Echinococcus granulosus GPCR family 2 0.0048 0.0292 0.0292
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0128 0.2197
Schistosoma mansoni hypothetical protein 0.0048 0.0292 0.029
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0064 0.0062
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni opsin-like receptor 0.0044 0.026 0.0257
Echinococcus granulosus neuropeptide FF receptor 2 0.0044 0.026 0.026
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0044 0.026 0.026
Echinococcus granulosus tm gpcr rhodopsin 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Schistosoma mansoni inositol monophosphatase 0.0036 0.0195 0.0193
Schistosoma mansoni coup transcription factor 0.0021 0.0064 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0026 0.011 0.0368
Echinococcus granulosus rhodopsin orphan GPCR 0.0044 0.026 0.026
Schistosoma mansoni hypothetical protein 0.0043 0.0253 0.025
Echinococcus granulosus g protein coupled receptor 0.0044 0.026 0.026
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0064 0.0064
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0292 0.0971
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Brugia malayi hypothetical protein 0.0091 0.0649 0.217
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0064 0.0062
Schistosoma mansoni biogenic amine receptor 0.0044 0.026 0.0257
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0044 0.026 0.026
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0207 0.0694
Echinococcus granulosus 7tm_1 domain containing protein 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0064 0.0062
Mycobacterium tuberculosis Conserved protein 0.0082 0.0576 0.135
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0057 0.0954
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.1152 0.3855
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0067 0.1118
Echinococcus multilocularis neuropeptide FF receptor 2 0.0044 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.0055 0.035 0.1173
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Plasmodium vivax SET domain protein, putative 0.0033 0.0166 0.2852
Loa Loa (eye worm) hypothetical protein 0.0082 0.0576 0.1931
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0372 0.2983 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0044 0.026 0.026
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Trichomonas vaginalis glutaminase, putative 0.0285 0.2258 1
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0211 0.0211
Schistosoma mansoni hypothetical protein 0.1219 1 1
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0195 0.0195
Trypanosoma brucei unspecified product 0.0014 0.0006 0.0071
Brugia malayi beta-lactamase 0.0082 0.0576 0.1924
Brugia malayi GnHR receptor homolog 0.0044 0.026 0.0863
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0215
Loa Loa (eye worm) neuropeptide F receptor 0.0044 0.026 0.0871
Trichomonas vaginalis set domain proteins, putative 0.026 0.2052 0.9088
Loa Loa (eye worm) hypothetical protein 0.0151 0.1145 0.3837
Brugia malayi beta-lactamase family protein 0.0082 0.0576 0.1924
Giardia lamblia DINP protein human, muc B family 0.002 0.0057 0.8535
Onchocerca volvulus 0.0033 0.0166 0.0513
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0057 0.0184
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0064 0.0064
Echinococcus multilocularis allatostatin A receptor 0.0044 0.026 0.026
Schistosoma mansoni patched 1 0.0045 0.0266 0.0264
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Echinococcus multilocularis sex peptide receptor 0.0044 0.026 0.026
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0057 0.0184
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0084 0.1424
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0166 0.0166
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0044 0.026 0.0871
Mycobacterium tuberculosis Probable lipase LipE 0.0082 0.0576 0.135
Echinococcus multilocularis musashi 0.0026 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Brugia malayi neuropeptide F receptor 0.0044 0.026 0.0863
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0192
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0057 0.0954
Onchocerca volvulus 0.0026 0.0114 0.025
Echinococcus granulosus biogenic amine 5HT receptor 0.0044 0.026 0.026
Echinococcus granulosus lamin 0.0026 0.0114 0.0114
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0064 0.0064
Trichomonas vaginalis ran, putative 0.0021 0.0067 0.0284
Echinococcus multilocularis muscleblind protein 0.0151 0.1145 0.1145
Loa Loa (eye worm) G-protein coupled receptor 0.0044 0.026 0.0871
Mycobacterium ulcerans esterase/lipase LipP 0.0082 0.0576 0.2542
Brugia malayi G-protein coupled receptor 0.0044 0.026 0.0863
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0002 0.0002
Onchocerca volvulus 0.0082 0.0576 0.2574
Echinococcus granulosus tachykinin peptides receptor 99D 0.0044 0.026 0.026
Mycobacterium leprae conserved hypothetical protein 0.0082 0.0576 0.8287
Brugia malayi RE15519p 0.0044 0.026 0.0863
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0064 0.0062
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0163 0.0379
Echinococcus multilocularis ferritin 0.0017 0.0036 0.0036
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0166 0.0164
Brugia malayi ORL1-like opioid receptor 0.0044 0.026 0.0863
Brugia malayi intermediate filament protein 0.0026 0.0114 0.0373
Leishmania major hypothetical protein, conserved 0.0027 0.012 0.2051
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0195 0.1957
Loa Loa (eye worm) hypothetical protein 0.0026 0.0114 0.0381
Schistosoma mansoni intermediate filament proteins 0.0026 0.0114 0.0111
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0067 0.0223
Schistosoma mansoni opsin-like receptor 0.0044 0.026 0.0257
Schistosoma mansoni biogenic amine receptor 0.0044 0.026 0.0257
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0057 0.0055
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0064 0.0215
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0044 0.026 0.0257
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0044 0.026 0.0257
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0064 0.0064
Echinococcus multilocularis fmrfamide receptor 0.0044 0.026 0.026
Echinococcus multilocularis orexin receptor type 2 0.0044 0.026 0.026
Brugia malayi G protein-coupled receptor F59B2.13 0.0044 0.026 0.0863
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0057 0.0954
Brugia malayi hypothetical protein 0.0027 0.012 0.0395
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0064 0.0064
Loa Loa (eye worm) TYRA-2 protein 0.0044 0.026 0.0871
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0064 0.0215
Brugia malayi hypothetical protein 0.0044 0.026 0.0863
Schistosoma mansoni biogenic amine receptor 0.0044 0.026 0.0257
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0064 0.0062
Echinococcus granulosus neuropeptides capa receptor 0.0044 0.026 0.026
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0044 0.026 0.0984
Echinococcus multilocularis snurportin 1 0.0302 0.2397 0.2397
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0064 0.0215
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0044 0.026 0.0257
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0013 0.0002 0.5
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0057 0.0129
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0044 0.026 0.0871
Echinococcus granulosus peptide allatostatin:somatostatin 0.0044 0.026 0.026
Echinococcus granulosus dna polymerase eta 0.002 0.0057 0.0057
Schistosoma mansoni ferritin 0.0017 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.0044 0.026 0.0871
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0057 0.0954
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0064 0.0062

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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