Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0712 | 0.5605 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0309 | 0.0603 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1138 | 0.1138 |
Echinococcus multilocularis | cathepsin b | 0.0138 | 0.512 | 0.4964 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0043 | 0.1035 | 0.1035 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0712 | 0.5605 |
Giardia lamblia | Cathepsin B precursor | 0.0048 | 0.1271 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0712 | 0.0712 |
Echinococcus multilocularis | fibrillin 1 | 0.0027 | 0.0344 | 0.0037 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0712 | 0.5553 |
Echinococcus granulosus | cathepsin b | 0.0138 | 0.512 | 0.512 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0037 | 0.0774 | 0.0774 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0712 | 0.0712 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0252 | 1 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0252 | 1 | 1 |
Onchocerca volvulus | 0.0035 | 0.0712 | 0.0712 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0252 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.1035 | 0.7553 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0712 | 0.0712 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus multilocularis | serotonin transporter | 0.0252 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.512 | 0.512 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6255 | 0.6255 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0309 | 0.0603 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0712 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0344 | 0.0344 |
Schistosoma mansoni | egf-like domain protein | 0.0027 | 0.0344 | 0.0344 |
Echinococcus multilocularis | cathepsin b | 0.0138 | 0.512 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0344 | 0.0344 |
Giardia lamblia | Cathepsin B precursor | 0.0048 | 0.1271 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0026 | 0.0309 | 0.399 |
Onchocerca volvulus | 0.0043 | 0.1035 | 0.1035 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0037 | 0.0774 | 0.64 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0043 | 0.1035 | 0.1035 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Plasmodium falciparum | amino acid transporter, putative | 0.0043 | 0.1035 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0344 | 0.0344 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.7553 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0712 | 0.5605 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0712 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0712 | 0.0712 |
Echinococcus granulosus | cathepsin b | 0.0138 | 0.512 | 0.512 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1138 | 0.1138 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.7553 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0712 | 0.1391 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.0309 | 0.0309 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0043 | 0.1035 | 0.1035 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1138 | 0.1138 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1138 | 0.1138 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.1035 | 0.7553 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0712 | 0.0712 |
Onchocerca volvulus | 0.0043 | 0.1035 | 0.1035 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0037 | 0.0774 | 0.1511 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0043 | 0.1035 | 0.1035 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0026 | 0.0309 | 0.0309 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0043 | 0.1035 | 0.075 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0037 | 0.0774 | 0.4835 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1138 | 0.0856 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0037 | 0.0774 | 1 |
Echinococcus granulosus | laminin | 0.0027 | 0.0344 | 0.0344 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0043 | 0.1035 | 0.1035 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0048 | 0.1271 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0037 | 0.0774 | 0.64 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0712 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0712 | 0.0712 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0309 | 0.399 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0309 | 0.0603 |
Toxoplasma gondii | cathepsin B | 0.0048 | 0.1271 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0712 | 0.4195 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0138 | 0.512 | 0.512 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1138 | 0.1138 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0037 | 0.0774 | 0.0774 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0712 | 0.0416 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0712 | 0.5605 |
Loa Loa (eye worm) | cysteine protease | 0.0026 | 0.0309 | 0.0309 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Giardia lamblia | Cathepsin B precursor | 0.0048 | 0.1271 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6255 | 0.6255 |
Brugia malayi | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Onchocerca volvulus | 0.0043 | 0.1035 | 0.1035 | |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0043 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | cathepsin B | 0.0048 | 0.1271 | 0.1271 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0043 | 0.1035 | 0.5 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0037 | 0.0774 | 0.609 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0027 | 0.0344 | 0.0344 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0344 | 0.0344 |
Echinococcus multilocularis | laminin | 0.0027 | 0.0344 | 0.0037 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0043 | 0.1035 | 0.1035 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0138 | 0.512 | 0.512 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0712 | 0.5605 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0026 | 0.0309 | 0.0309 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0027 | 0.0344 | 0.0344 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0309 | 0.0309 |
Brugia malayi | Fibulin-1 precursor | 0.0027 | 0.0344 | 0.0344 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0037 | 0.0774 | 0.048 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0026 | 0.0309 | 0.0309 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0037 | 0.0774 | 0.609 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0712 | 0.5605 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 1 | 1 |
Echinococcus granulosus | serotonin transporter | 0.0252 | 1 | 1 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0027 | 0.0344 | 0.0344 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0027 | 0.0344 | 0.037 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0712 | 0.0712 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0026 | 0.0309 | 0.0309 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0252 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0712 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0309 | 0.0309 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0138 | 0.512 | 0.512 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0048 | 0.1271 | 0.2482 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0043 | 0.1035 | 0.1035 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0712 | 0.0712 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0026 | 0.0309 | 0.0309 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0037 | 0.0774 | 0.0076 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0043 | 0.1035 | 0.075 |
Loa Loa (eye worm) | serotonin transporter b | 0.0252 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0048 | 0.1271 | 1 |
Onchocerca volvulus | 0.0035 | 0.0712 | 0.0712 | |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1138 | 0.1138 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.1035 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Onchocerca volvulus | Arrow homolog | 0.0027 | 0.0344 | 0.0344 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0037 | 0.0774 | 0.1511 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0043 | 0.1035 | 0.075 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0037 | 0.0774 | 0.0774 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0712 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1138 | 0.0856 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0712 | 0.0712 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus multilocularis | geminin | 0.0165 | 0.6255 | 0.6136 |
Onchocerca volvulus | 0.0035 | 0.0712 | 0.0712 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.8848 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0712 | 0.4195 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0037 | 0.0774 | 0.5 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0043 | 0.1035 | 0.1035 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0712 | 0.0712 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0309 | 0.0309 |
Toxoplasma gondii | exonuclease III APE | 0.0037 | 0.0774 | 0.4835 |
Plasmodium falciparum | transporter, putative | 0.0043 | 0.1035 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0037 | 0.0774 | 0.0774 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.075 |
Onchocerca volvulus | Cathepsin L homolog | 0.0026 | 0.0309 | 0.0309 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0026 | 0.0309 | 0.0603 |
Plasmodium vivax | amine transporter, putative | 0.0043 | 0.1035 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0252 | 1 | 1 |
Echinococcus granulosus | Tolloid protein 1 | 0.0027 | 0.0344 | 0.0344 |
Onchocerca volvulus | 0.0026 | 0.0309 | 0.0309 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0309 | 0.0309 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.1035 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0138 | 0.512 | 0.512 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0027 | 0.0344 | 0.037 |
Loa Loa (eye worm) | fibroinase | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | ctsf protein | 0.0026 | 0.0309 | 0.0309 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0712 | 0.4195 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0027 | 0.0344 | 0.0037 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0043 | 0.1035 | 0.1035 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0043 | 0.1035 | 0.075 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0043 | 0.1035 | 0.1035 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0026 | 0.0309 | 0.0603 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.1035 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.1035 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0043 | 0.1035 | 0.1035 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0309 | 0.399 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0037 | 0.0774 | 0.4835 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0048 | 0.1271 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0048 | 0.1271 | 0.1271 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0344 | 0.0344 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0712 | 0.5 |
Onchocerca volvulus | 0.0252 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0712 | 0.0712 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0027 | 0.0344 | 0.0344 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0138 | 0.512 | 0.512 |
Echinococcus granulosus | geminin | 0.0165 | 0.6255 | 0.6255 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0309 | 0.243 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0309 | 0.0309 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0027 | 0.0344 | 0.0344 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0712 | 0.1391 |
Schistosoma mansoni | ap endonuclease | 0.0037 | 0.0774 | 0.0774 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0138 | 0.512 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.7553 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0027 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1035 | 0.1035 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0037 | 0.0774 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1138 | 0.1138 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 6.37 % | Antidepressant-like activity in Swiss albino mouse assessed as decrease in immobility time at 0.5 mg/kg, ip measured for 5 mins by forced swimming test relative to control | ChEMBL. | 25488839 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.