Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | O-methyltransferase | 0.0066 | 0.0824 | 0.3109 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0572 | 0.2126 |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Brugia malayi | serpin | 0.0029 | 0.0236 | 0.089 |
Loa Loa (eye worm) | serpin | 0.0029 | 0.0236 | 0.089 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0572 | 0.2126 |
Schistosoma mansoni | o-methyltransferase | 0.0066 | 0.0824 | 0.3342 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0061 | 0.0743 | 0.2775 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0059 | 0.0326 |
Echinococcus multilocularis | serine protease inhibitor | 0.0029 | 0.0236 | 0.0851 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.004 | 0.0402 | 0.2229 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4117 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0059 | 0.0271 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0572 | 0.2126 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0113 | 0.0425 |
Loa Loa (eye worm) | serpin | 0.0029 | 0.0236 | 0.089 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.1648 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0041 | 0.0112 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.1648 | |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0061 | 0.0743 | 0.2805 |
Brugia malayi | serpin (BmSERPIN) | 0.0029 | 0.0236 | 0.089 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0402 | 0.2228 |
Leishmania major | alpha glucosidase II subunit, putative | 0.004 | 0.0402 | 0.2069 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0022 | 0.0113 | 0.0423 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0113 | 0.0578 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0061 | 0.0743 | 0.2775 |
Toxoplasma gondii | serpin (serine proteinase inhibitor) superfamily protein | 0.0029 | 0.0236 | 0.1281 |
Loa Loa (eye worm) | O-methyltransferase | 0.0066 | 0.0824 | 0.3109 |
Brugia malayi | serpin | 0.0029 | 0.0236 | 0.089 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.2794 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0041 | 0.0112 |
Echinococcus granulosus | bloom syndrome protein | 0.0022 | 0.0113 | 0.0384 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0061 | 0.0743 | 0.2794 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.004 | 0.0402 | 0.2228 |
Echinococcus multilocularis | Rab geranylgeranyltransferase, beta subunit | 0.0044 | 0.0478 | 0.1769 |
Echinococcus multilocularis | geminin | 0.0166 | 0.2443 | 0.9215 |
Echinococcus multilocularis | Estrogen regulated protein EP45 | 0.0029 | 0.0236 | 0.0851 |
Brugia malayi | serpin | 0.0029 | 0.0236 | 0.089 |
Echinococcus multilocularis | protein farnesyltransferase subunit beta | 0.0124 | 0.1765 | 0.6647 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0011 | 0.0043 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0572 | 0.216 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0478 | 0.1804 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0572 | 0.2126 |
Echinococcus granulosus | protein farnesyltransferase subunit beta | 0.0124 | 0.1765 | 0.6647 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.1648 | |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.004 | 0.0402 | 0.2228 |
Schistosoma mansoni | serpin | 0.0029 | 0.0236 | 0.0924 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0572 | 0.2307 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0059 | 0.0221 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.004 | 0.0402 | 0.1482 |
Toxoplasma gondii | Rab geranylgeranyl transferase type II beta subunit, putative | 0.0044 | 0.0478 | 0.2662 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.2443 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0041 | 0.0112 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0059 | 0.018 |
Schistosoma mansoni | o-methyltransferase | 0.0066 | 0.0824 | 0.3342 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Schistosoma mansoni | serine protease inhibitors serpins | 0.0029 | 0.0236 | 0.0924 |
Echinococcus granulosus | Estrogen regulated protein EP45 | 0.0029 | 0.0236 | 0.0851 |
Schistosoma mansoni | serine protease inhibitors serpins | 0.0029 | 0.0236 | 0.0924 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0572 | 0.2307 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.2443 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Schistosoma mansoni | serine protease inhibitors serpins | 0.0029 | 0.0236 | 0.0924 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0059 | 0.0303 |
Brugia malayi | O-methyltransferase family protein | 0.0066 | 0.0824 | 0.3109 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0572 | 0.216 |
Giardia lamblia | Prenyltransferase | 0.0124 | 0.1765 | 1 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.2794 |
Echinococcus granulosus | geminin | 0.0166 | 0.2443 | 0.9215 |
Trypanosoma cruzi | Protein prenyltransferase alpha subunit repeat, putative | 0.0061 | 0.0743 | 0.2794 |
Trichomonas vaginalis | geranylgeranyl transferase type beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0478 | 0.1804 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0011 | 0.0043 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0022 | 0.0113 | 0.0578 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0011 | 0.0058 |
Brugia malayi | BmSERPIN, truncated | 0.0029 | 0.0236 | 0.089 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Plasmodium falciparum | geranylgeranyl transferase type2 beta subunit, putative | 0.0044 | 0.0478 | 0.2662 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0402 | 0.1512 |
Loa Loa (eye worm) | serpin protein 6 | 0.0029 | 0.0236 | 0.089 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0061 | 0.0743 | 0.3011 |
Wolbachia endosymbiont of Brugia malayi | O-methyltransferase | 0.0066 | 0.0824 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0059 | 0.0222 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0061 | 0.0743 | 0.2805 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0645 | 0.2435 |
Brugia malayi | O-methyltransferase family protein | 0.0066 | 0.0824 | 0.3109 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0113 | 0.0425 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0178 | 0.265 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.004 | 0.0402 | 0.2228 |
Schistosoma mansoni | serpin | 0.0029 | 0.0236 | 0.0924 |
Entamoeba histolytica | geranylgeranyl transferase beta subunit | 0.0126 | 0.1805 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0041 | 0.0112 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0126 | 0.1805 | 0.6814 |
Schistosoma mansoni | o-methyltransferase | 0.0066 | 0.0824 | 0.3342 |
Plasmodium falciparum | geranylgeranyltransferase, putative | 0.0044 | 0.0478 | 0.2662 |
Echinococcus granulosus | serine protease inhibitor | 0.0029 | 0.0236 | 0.0851 |
Schistosoma mansoni | serine protease inhibitors serpins | 0.0029 | 0.0236 | 0.0924 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Schistosoma mansoni | geranylgeranyl transferase type I beta subunit | 0.0126 | 0.1805 | 0.7379 |
Echinococcus granulosus | Estrogen regulated protein EP45 | 0.0029 | 0.0236 | 0.0851 |
Mycobacterium leprae | PROBABLE METHYLTRANSFERASE | 0.0066 | 0.0824 | 0.5 |
Echinococcus multilocularis | bloom syndrome protein | 0.0022 | 0.0113 | 0.0384 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.1648 | |
Loa Loa (eye worm) | serpin | 0.0029 | 0.0236 | 0.089 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0011 | 0.0042 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0061 | 0.0743 | 0.4174 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0061 | 0.0743 | 0.3011 |
Entamoeba histolytica | serine protease inhibitor, putative | 0.0029 | 0.0236 | 0.1307 |
Brugia malayi | Probable protein farnesyltransferase beta subunit, putative | 0.0044 | 0.0478 | 0.1804 |
Plasmodium vivax | geranylgeranyltransferase, putative | 0.0044 | 0.0478 | 0.2662 |
Loa Loa (eye worm) | serpin | 0.0029 | 0.0236 | 0.089 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0402 | 0.2228 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0365 | 0.1379 |
Mycobacterium tuberculosis | Probable catechol-O-methyltransferase | 0.0567 | 0.8937 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0059 | 0.0326 |
Echinococcus granulosus | geranylgeranyl transferase type I beta subunit | 0.0126 | 0.1805 | 0.68 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0113 | 0.0578 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0041 | 0.0112 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0015 | 0.0011 | 0.0042 |
Schistosoma mansoni | DNA helicase recq1 | 0.0022 | 0.0113 | 0.0417 |
Echinococcus multilocularis | geranylgeranyl transferase type I beta subunit | 0.0126 | 0.1805 | 0.68 |
Echinococcus multilocularis | geranylgeranyl transferase type 2 subunit alpha | 0.0061 | 0.0743 | 0.2775 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.008 | 0.1048 | 0.5913 |
Trichomonas vaginalis | type I geranylgeranyltransferase beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4117 |
Brugia malayi | serpin | 0.0029 | 0.0236 | 0.089 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0022 | 0.0113 | 0.0384 |
Entamoeba histolytica | Rab geranylgeranyltransferase beta subunit, putative | 0.0044 | 0.0478 | 0.2648 |
Echinococcus granulosus | protein prenyltransferase alpha subunit | 0.0061 | 0.0743 | 0.2775 |
Schistosoma mansoni | geranylgeranyl transferase type II beta subunit | 0.0044 | 0.0478 | 0.192 |
Trichomonas vaginalis | protein farnesyltransferase beta subunit, putative | 0.0044 | 0.0478 | 0.2648 |
Trichomonas vaginalis | protein farnesyltransferase beta subunit, putative | 0.0044 | 0.0478 | 0.2648 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0365 | 0.1457 |
Entamoeba histolytica | Rab geranylgeranyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4117 |
Loa Loa (eye worm) | RecQ helicase | 0.0022 | 0.0113 | 0.0425 |
Toxoplasma gondii | hypothetical protein | 0.0061 | 0.0743 | 0.4174 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0022 | 0.0113 | 0.0624 |
Echinococcus granulosus | serine protease inhibitor | 0.0029 | 0.0236 | 0.0851 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0022 | 0.0113 | 0.0423 |
Plasmodium vivax | geranylgeranyl transferase type2 beta subunit, putative | 0.0044 | 0.0478 | 0.2662 |
Schistosoma mansoni | alpha-glucosidase | 0.0154 | 0.2248 | 0.9197 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.004 | 0.0402 | 0.1482 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0011 | 0.0042 |
Brugia malayi | serpin | 0.0029 | 0.0236 | 0.089 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0402 | 0.1512 |
Trypanosoma brucei | geranylgeranyl transferase type II beta subunit, putative | 0.0044 | 0.0478 | 0.1797 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4174 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.004 | 0.0402 | 0.1518 |
Echinococcus granulosus | serine protease inhibitor | 0.0029 | 0.0236 | 0.0851 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0059 | 0.0221 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0061 | 0.0743 | 0.2794 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0124 | 0.1765 | 0.6661 |
Leishmania major | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.3824 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.004 | 0.0402 | 0.2228 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0061 | 0.0743 | 0.2794 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0645 | 0.2435 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0124 | 0.1765 | 0.6661 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0041 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0041 | 0.0154 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.004 | 0.0402 | 0.2228 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0572 | 0.2307 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0124 | 0.1765 | 0.6634 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0059 | 0.0326 |
Entamoeba histolytica | recQ family helicase, putative | 0.0022 | 0.0113 | 0.0624 |
Onchocerca volvulus | 0.0061 | 0.0743 | 0.5191 | |
Mycobacterium ulcerans | methyltransferase | 0.0066 | 0.0824 | 0.077 |
Brugia malayi | BmSERPIN | 0.0029 | 0.0236 | 0.089 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0178 | 0.265 | 1 |
Leishmania major | lanosterol synthase, putative | 0.0135 | 0.1944 | 1 |
Brugia malayi | serpin | 0.0029 | 0.0236 | 0.089 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0824 | 0.3109 |
Echinococcus multilocularis | Estrogen regulated protein EP45 | 0.0029 | 0.0236 | 0.0851 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0022 | 0.0113 | 0.0425 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0022 | 0.0113 | 0.0425 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0022 | 0.0113 | 0.0315 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0061 | 0.0743 | 0.2794 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0743 | 0.2805 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.004 | 0.0402 | 0.2228 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0402 | 0.2228 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4117 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.0124 | 0.1765 | 0.7213 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4117 |
Mycobacterium tuberculosis | Probable methyltransferase | 0.0066 | 0.0824 | 0.091 |
Brugia malayi | serpin (BmSERPIN) | 0.0029 | 0.0236 | 0.089 |
Echinococcus granulosus | plasminogen activator inhibitor 2 | 0.0029 | 0.0236 | 0.0851 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0044 | 0.0478 | 0.1797 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.058 | 0.2338 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0061 | 0.0743 | 0.4012 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0402 | 0.2228 |
Toxoplasma gondii | protease inhibitor PI1 | 0.0029 | 0.0236 | 0.1281 |
Schistosoma mansoni | alpha glucosidase | 0.004 | 0.0402 | 0.1608 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0041 | 0.0122 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0022 | 0.0113 | 0.058 |
Echinococcus multilocularis | serine protease inhibitor | 0.0029 | 0.0236 | 0.0851 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0059 | 0.018 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0061 | 0.0743 | 0.2794 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0061 | 0.0743 | 0.2805 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0061 | 0.0743 | 0.2805 |
Giardia lamblia | Serpin 1 | 0.0029 | 0.0236 | 0.1038 |
Trypanosoma cruzi | geranylgeranyl transferase type II beta subunit, putative | 0.0044 | 0.0478 | 0.1797 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0059 | 0.5 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0059 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0645 | 0.2435 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0178 | 0.265 | 1 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.0044 | 0.0478 | 0.2662 |
Schistosoma mansoni | alpha-glucosidase | 0.0154 | 0.2248 | 0.9197 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.1648 | |
Trypanosoma brucei | lanosterol synthase | 0.0179 | 0.2661 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0041 | 0.0122 |
Onchocerca volvulus | 0.0066 | 0.0824 | 0.5754 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0059 | 0.0221 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0178 | 0.265 | 1 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0179 | 0.2661 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0011 | 0.0043 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.0124 | 0.1765 | 1 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.1648 | |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0179 | 0.2661 | 1 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Schistosoma mansoni | geranylgeranyl transferase type I beta subunit | 0.0126 | 0.1805 | 0.7379 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4117 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0179 | 0.2661 | 0.2968 |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.0124 | 0.1765 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0022 | 0.0113 | 0.0624 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0124 | 0.1765 | 0.6634 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0041 | 0.0154 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0022 | 0.0113 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Trypanosoma brucei | protein farnesyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.2794 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0365 | 0.1379 |
Echinococcus granulosus | geranylgeranyl transferase type 2 subunit alpha | 0.0061 | 0.0743 | 0.2775 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0059 | 0.0222 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0041 | 0.0122 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0041 | 0.0112 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0022 | 0.0113 | 0.0425 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0044 | 0.0478 | 0.1797 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0044 | 0.0478 | 0.2457 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0059 | 0.0196 |
Schistosoma mansoni | serine protease inhibitors serpins | 0.0029 | 0.0236 | 0.0924 |
Brugia malayi | serpin precursor | 0.0029 | 0.0236 | 0.089 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0022 | 0.0113 | 0.0384 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0059 | 0.0053 |
Leishmania major | geranylgeranyltransferase, putative | 0.0044 | 0.0478 | 0.246 |
Onchocerca volvulus | 0.0066 | 0.0824 | 0.5754 | |
Brugia malayi | O-methyltransferase family protein | 0.0066 | 0.0824 | 0.3109 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0061 | 0.0743 | 0.4012 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0022 | 0.0113 | 0.0624 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0178 | 0.265 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.004 | 0.0402 | 0.1518 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0059 | 0.0196 |
Schistosoma mansoni | o-methyltransferase | 0.0066 | 0.0824 | 0.3342 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0011 | 0.0042 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0402 | 0.2228 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0126 | 0.1805 | 0.6814 |
Schistosoma mansoni | serine protease inhibitors serpins | 0.0029 | 0.0236 | 0.0924 |
Plasmodium falciparum | protein farnesyltransferase subunit beta | 0.0124 | 0.1765 | 1 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.0124 | 0.1765 | 0.6634 |
Plasmodium vivax | protein prenyltransferase alpha subunit, putative | 0.0061 | 0.0743 | 0.4174 |
Echinococcus multilocularis | protein prenyltransferase alpha subunit | 0.0061 | 0.0743 | 0.2775 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Onchocerca volvulus | 0.0103 | 0.1432 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0041 | 0.0122 |
Schistosoma mansoni | DNA helicase recq5 | 0.0022 | 0.0113 | 0.0417 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.0126 | 0.1805 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.004 | 0.0402 | 0.1512 |
Brugia malayi | Serpin protein 6 | 0.0029 | 0.0236 | 0.089 |
Plasmodium falciparum | geranylgeranyl transferase type-2 subunit alpha, putative | 0.0061 | 0.0743 | 0.4174 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0022 | 0.0113 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.089 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.0124 | 0.1765 | 0.9777 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0645 | 0.2435 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0041 | 0.0154 |
Leishmania major | farnesyltransferase beta subunit | 0.0124 | 0.1765 | 0.9081 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0022 | 0.0113 | 0.0578 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0059 | 0.0271 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC12 (binding) | > 100 uM | Activity at human alpha4beta2 nAChR expressed in Xenopus oocytes assessed as potentiation of acetylcholine-induced response by patch-clamp electrophysiology | ChEMBL. | 18805006 |
Efficacy (binding) | = 10 % | Activity at human alpha4beta2 nAChR expressed in Xenopus oocytes assessed as potentiation of acetylcholine-induced response by patch-clamp electrophysiology relative to nicotine | ChEMBL. | 18805006 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.