Detailed information for compound 1002587

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 567.481 | Formula: C28H26NO10P
  • H donors: 4 H acceptors: 5 LogP: 1.05 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: O[C@H]1C=C2[C@H]([C@@H]([C@@H]1O)O)NC(=O)c1c2cc2OCOc2c1OP(=O)(OCc1ccccc1)OCc1ccccc1
  • InChi: 1S/C28H26NO10P/c30-20-11-19-18-12-21-26(36-15-35-21)27(22(18)28(33)29-23(19)25(32)24(20)31)39-40(34,37-13-16-7-3-1-4-8-16)38-14-17-9-5-2-6-10-17/h1-12,20,23-25,30-32H,13-15H2,(H,29,33)/t20-,23+,24+,25-/m0/s1
  • InChiKey: FXOYPNTXMPNYQD-KTJVCJKDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0903 0.1753
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0382 0.0722
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0064 0.0903 0.8438
Echinococcus granulosus dna polymerase eta 0.0019 0.0016 0.0012
Loa Loa (eye worm) TAR-binding protein 0.021 0.3772 0.7428
Loa Loa (eye worm) phosphatidylinositol 3 0.0034 0.0314 0.0609
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.1189 1
Toxoplasma gondii ABC1 family protein 0.0074 0.1099 0.5709
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.021 0.3772 0.7428
Mycobacterium ulcerans bacterioferritin BfrA 0.0052 0.0669 0.2488
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0019 0.0038
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0031 0.0244 0.1944
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Entamoeba histolytica protein kinase rad3, putative 0.0019 0.0019 0.003
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.1099 0.413
Brugia malayi hypothetical protein 0.0079 0.1189 0.2343
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.1099 0.121
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0052 0.0669 0.0729
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0778 0.7246
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.06 0.1173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0065 0.0188
Mycobacterium tuberculosis Conserved protein 0.0074 0.1099 0.121
Mycobacterium leprae Probable lipase LipE 0.0074 0.1099 0.4018
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0064 0.0903 0.8438
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1099 0.9232
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.1099 0.2141
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.1099 0.2166
Echinococcus granulosus GPCR family 2 0.0049 0.06 0.0595
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.1099 0.2141
Brugia malayi hypothetical protein 0.0051 0.064 0.1261
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0065 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0065 0.0061
Echinococcus multilocularis tar DNA binding protein 0.021 0.3772 0.3769
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.1189 1
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0152 0.2639 0.5183
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.1099 0.121
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.1067 0.1053
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0074 0.0493
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Brugia malayi RNA recognition motif domain containing protein 0.021 0.3772 0.7431
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.1541 0.303
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.1099 0.1095
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0064 0.0903 0.0888
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0065 0.0061
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0382 0.0722
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.06 0.0595
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0055 0.0722 0.6018
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.1189 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0494 0.0945
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0778 0.1524
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Echinococcus granulosus ferritin 0.0052 0.0669 0.0664
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.1541 0.1537
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0778 0.649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.2675 0.5267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0609 0.1171
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0427 0.0813
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0052 0.0669 0.0729
Loa Loa (eye worm) hypothetical protein 0.0022 0.0063 0.0115
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.1099 0.121
Loa Loa (eye worm) hypothetical protein 0.0079 0.1189 0.2336
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.1715 0.3378
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1099 0.9232
Schistosoma mansoni apoferritin-2 0.0052 0.0669 0.0654
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.1541 0.3036
Brugia malayi MH2 domain containing protein 0.0118 0.1953 0.3848
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0778 0.649
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.5076 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0903 0.1753
Trichomonas vaginalis ferritin, putative 0.0052 0.0669 0.129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0494 0.0945
Schistosoma mansoni ferritin light chain 0.0052 0.0669 0.0654
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0052 0.0669 0.847
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0065 0.0188
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.2146 0.2134
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Entamoeba histolytica hypothetical protein 0.0035 0.0325 0.2936
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.3398 0.6685
Leishmania major phosphatidylinositol 3-kinase, putative 0.0034 0.0314 0.2534
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0034 0.0314 0.0309
Mycobacterium leprae conserved hypothetical protein 0.0074 0.1099 0.4018
Schistosoma mansoni hypothetical protein 0.0105 0.1715 0.1701
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.1541 0.1527
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0541 0.1037
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.1099 0.1085
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.0074 0.0493
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0778 0.1532
Loa Loa (eye worm) hypothetical protein 0.0028 0.0195 0.0375
Mycobacterium ulcerans lipase LipD 0.0074 0.1099 0.413
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0016 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0494 0.0945
Echinococcus granulosus tar DNA binding protein 0.021 0.3772 0.3769
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0778 0.6337
Schistosoma mansoni apoferritin-2 0.0052 0.0669 0.0654
Brugia malayi beta-lactamase 0.0074 0.1099 0.2166
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0016 0.0023
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0334 0.033
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0065 0.0061
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.2675 0.5271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0325 0.061
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.06 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0063 0.0092
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Mycobacterium ulcerans bacterioferritin BfrB 0.0052 0.0669 0.2488
Schistosoma mansoni cpg binding protein 0.0063 0.0888 0.0874
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.5076 1
Trichomonas vaginalis esterase, putative 0.0074 0.1099 0.2141
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0778 0.2904
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Onchocerca volvulus 0.0074 0.1099 0.1167
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.1541 0.1537
Loa Loa (eye worm) RNA binding protein 0.021 0.3772 0.7428
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0029
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Echinococcus multilocularis geminin 0.0526 1 1
Onchocerca volvulus 0.0074 0.1099 0.1167
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.1099 0.121
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0019 0.0019 0.0015
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0065 0.0049
Schistosoma mansoni cpg binding protein 0.0063 0.0888 0.0874
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0778 1
Plasmodium vivax hypothetical protein, conserved 0.0074 0.1099 0.9198
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.1099 0.9232
Brugia malayi RNA binding protein 0.021 0.3772 0.7431
Brugia malayi hypothetical protein 0.0073 0.1067 0.2102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.1099 0.2141
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0034 0.0314 0.2534
Brugia malayi beta-lactamase family protein 0.0074 0.1099 0.2166
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0778 0.649
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.1189 0.6205
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0034 0.0314 0.0309
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0064 0.0903 0.7559
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0065 0.0055
Giardia lamblia GTOR 0.0064 0.0903 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0019 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.1541 0.1537
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.1953 0.3842
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0152 0.2639 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.1099 0.1095
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0471 0.0899
Brugia malayi TAR-binding protein 0.021 0.3772 0.7431
Schistosoma mansoni fkbp-rapamycin associated protein 0.0019 0.0019 0.0003
Echinococcus granulosus serine protein kinase ATM 0.0035 0.0325 0.032
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0019 0.0019 0.003
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.1099 0.2159
Echinococcus multilocularis ferritin 0.0052 0.0669 0.0664
Toxoplasma gondii exonuclease III APE 0.0058 0.0778 0.3937
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0064 0.0903 0.7559
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.1099 0.413
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.1099 0.2141
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.1099 0.2141
Echinococcus granulosus dna polymerase kappa 0.0019 0.0016 0.0012
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0325 0.064
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0035 0.0325 0.0309
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0064 0.0903 0.7559
Loa Loa (eye worm) phosphatidylinositol 3 0.0064 0.0903 0.1772
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0032
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0131 0.0978
Echinococcus multilocularis serine protein kinase ATM 0.0035 0.0325 0.032
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.1879 1
Schistosoma mansoni ferritin light chain 0.0052 0.0669 0.0654
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0064 0.0903 0.0899
Toxoplasma gondii target of rapamycin (TOR), putative 0.0053 0.0676 0.3376
Mycobacterium ulcerans beta-lactamase 0.0074 0.1099 0.413
Schistosoma mansoni hypothetical protein 0.0073 0.1067 0.1053
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0778 0.0773
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.3206 1
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0065 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.1541 0.1537
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0382 0.0722
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0152 0.2639 0.2929
Onchocerca volvulus 0.0074 0.1099 0.1167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Brugia malayi CXXC zinc finger family protein 0.006 0.0821 0.1618
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0065 0.0061
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0064 0.0903 0.1779
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0065 0.0055
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0034 0.0314 0.0298
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0064 0.0903 0.7559
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Echinococcus multilocularis GPCR, family 2 0.0049 0.06 0.0595
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Brugia malayi beta-lactamase family protein 0.0074 0.1099 0.2166
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.1099 0.121
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.1541 0.1527
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.1541 0.1527
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Toxoplasma gondii FATC domain-containing protein 0.0035 0.0325 0.1442
Schistosoma mansoni cpg binding protein 0.006 0.0821 0.0806
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0065 0.0055
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.3398 0.6685
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.1189 1
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.1067 0.1063
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Schistosoma mansoni ap endonuclease 0.0058 0.0778 0.0763
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0032
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.1067 0.1063
Mycobacterium tuberculosis Probable aminotransferase 0.0152 0.2639 0.2929
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0778 0.649
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0064 0.0903 0.7559
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0065 0.5
Echinococcus multilocularis expressed protein 0.0052 0.0669 0.0664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0019 0.0006
Schistosoma mansoni hypothetical protein 0.0526 1 1
Leishmania major hypothetical protein, conserved 0.0079 0.1189 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.0195 0.1523
Mycobacterium tuberculosis Conserved protein 0.0074 0.1099 0.121
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0055 0.0722 0.6018
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0065 0.0188
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0035 0.0325 0.2629
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.1953 0.3842
Loa Loa (eye worm) hypothetical protein 0.0049 0.06 0.1173
Echinococcus granulosus Aminotransferase class III 0.0022 0.0065 0.0061
Mycobacterium ulcerans hypothetical protein 0.0074 0.1099 0.413
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0778 0.0851
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0035 0.0325 0.2629
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.1099 0.121
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0019 0.0019 0.0027
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Leishmania major hypothetical protein, conserved 0.0074 0.1099 0.9232
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0065 0.0129
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0065 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0778 0.1505
Mycobacterium tuberculosis Conserved protein 0.0074 0.1099 0.121
Echinococcus multilocularis dna polymerase eta 0.0019 0.0016 0.0012
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0064 0.0903 0.0899
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0821 0.161
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0778 0.6337
Brugia malayi Latrophilin receptor protein 2 0.0049 0.06 0.1181
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0065 0.0188
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0334 0.033
Schistosoma mansoni hypothetical protein 0.0035 0.0334 0.0319
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0012
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0778 1
Loa Loa (eye worm) beta-lactamase 0.0074 0.1099 0.2159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Mycobacterium ulcerans hypothetical protein 0.0152 0.2639 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.2675 0.5271
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0314 0.0618
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0019 0.0019 0.0015
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0065 0.0014
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0064 0.0903 0.7559
Schistosoma mansoni ap endonuclease 0.0058 0.0778 0.0763
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0778 0.0773
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.06 0.0595
Echinococcus granulosus expressed protein 0.0052 0.0669 0.0664
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.06 0.1181
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.1189 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0903 0.1753
Trypanosoma cruzi target of rapamycin kinase 3 0.0055 0.0722 0.6018
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0152 0.2639 1
Loa Loa (eye worm) hypothetical protein 0.0154 0.2675 0.5267
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0052 0.0669 0.2345
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0778 0.8587
Echinococcus multilocularis cpg binding protein 0.0063 0.0888 0.0884
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.1099 0.1085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.1189 1
Echinococcus granulosus cpg binding protein 0.0063 0.0888 0.0884
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.06 0.0595
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0474 0.8969 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Loa Loa (eye worm) hypothetical protein 0.0105 0.1715 0.3372
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0541 0.1037
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.1099 0.121
Schistosoma mansoni hypothetical protein 0.0526 1 1
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0778 0.1505

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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