Detailed information for compound 1002587

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 567.481 | Formula: C28H26NO10P
  • H donors: 4 H acceptors: 5 LogP: 1.05 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: O[C@H]1C=C2[C@H]([C@@H]([C@@H]1O)O)NC(=O)c1c2cc2OCOc2c1OP(=O)(OCc1ccccc1)OCc1ccccc1
  • InChi: 1S/C28H26NO10P/c30-20-11-19-18-12-21-26(36-15-35-21)27(22(18)28(33)29-23(19)25(32)24(20)31)39-40(34,37-13-16-7-3-1-4-8-16)38-14-17-9-5-2-6-10-17/h1-12,20,23-25,30-32H,13-15H2,(H,29,33)/t20-,23+,24+,25-/m0/s1
  • InChiKey: FXOYPNTXMPNYQD-KTJVCJKDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0526 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0195 0.0375
Loa Loa (eye worm) phosphatidylinositol 3 0.0034 0.0314 0.0609
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0019 0.0019 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.1099 0.121
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.1541 0.303
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0541 0.1037
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0019 0.0019 0.003
Loa Loa (eye worm) phosphatidylinositol 3 0.0064 0.0903 0.1772
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0541 0.1037
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0052 0.0669 0.2345
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0778 0.6337
Loa Loa (eye worm) hypothetical protein 0.0154 0.2675 0.5267
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0065 0.0061
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.0074 0.0493
Echinococcus granulosus tar DNA binding protein 0.021 0.3772 0.3769
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Echinococcus granulosus dna polymerase eta 0.0019 0.0016 0.0012
Brugia malayi hypothetical protein 0.0073 0.1067 0.2102
Schistosoma mansoni apoferritin-2 0.0052 0.0669 0.0654
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0035 0.0325 0.0309
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0022 0.0065 0.0188
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0064 0.0903 0.7559
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0494 0.0945
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.06 0.0595
Schistosoma mansoni ap endonuclease 0.0058 0.0778 0.0763
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.1541 0.1537
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0022 0.0065 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Echinococcus multilocularis cpg binding protein 0.0063 0.0888 0.0884
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0152 0.2639 1
Mycobacterium tuberculosis Conserved protein 0.0074 0.1099 0.121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0019 0.0006
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0052 0.0669 0.0729
Echinococcus granulosus ornithine aminotransferase 0.0022 0.0065 0.0061
Trichomonas vaginalis esterase, putative 0.0074 0.1099 0.2141
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0064 0.0903 0.7559
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0052 0.0669 0.847
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.1541 0.1527
Entamoeba histolytica hypothetical protein 0.0035 0.0325 0.2936
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0427 0.0813
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0778 0.2904
Echinococcus multilocularis tar DNA binding protein 0.021 0.3772 0.3769
Brugia malayi beta-lactamase family protein 0.0074 0.1099 0.2166
Trichomonas vaginalis ferritin, putative 0.0052 0.0669 0.129
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0065 0.0188
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0064 0.0903 0.8438
Trypanosoma cruzi target of rapamycin kinase 3 0.0055 0.0722 0.6018
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Onchocerca volvulus 0.0074 0.1099 0.1167
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.1099 0.1085
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.1099 0.1095
Leishmania major phosphatidylinositol 3-kinase, putative 0.0034 0.0314 0.2534
Brugia malayi MH2 domain containing protein 0.0118 0.1953 0.3848
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.1189 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.1189 1
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.1099 0.413
Onchocerca volvulus Glucosylceramidase homolog 0.0181 0.3206 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0032
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0031 0.0244 0.1944
Echinococcus granulosus serine protein kinase ATM 0.0035 0.0325 0.032
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0034 0.0314 0.0309
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0494 0.0945
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0019 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0382 0.0722
Mycobacterium leprae conserved hypothetical protein 0.0074 0.1099 0.4018
Mycobacterium tuberculosis Conserved protein 0.0074 0.1099 0.121
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.06 0.0595
Schistosoma mansoni hypothetical protein 0.0105 0.1715 0.1701
Loa Loa (eye worm) RNA binding protein 0.021 0.3772 0.7428
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0778 0.8587
Onchocerca volvulus 0.0074 0.1099 0.1167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0903 0.1753
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.1541 0.1527
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0022 0.0065 0.0188
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Entamoeba histolytica protein kinase rad3, putative 0.0019 0.0019 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Mycobacterium ulcerans L-lysine aminotransferase 0.0022 0.0065 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0034 0.0314 0.0298
Brugia malayi hypothetical protein 0.0051 0.064 0.1261
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0064 0.0903 0.7559
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0778 0.1532
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0325 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0022 0.0065 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0325 0.061
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0152 0.2639 1
Mycobacterium ulcerans acetylornithine aminotransferase 0.0022 0.0065 0.0188
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0064 0.0903 0.0899
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.1099 0.2141
Mycobacterium ulcerans bacterioferritin BfrB 0.0052 0.0669 0.2488
Echinococcus multilocularis dna polymerase eta 0.0019 0.0016 0.0012
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0073 0.1067 0.1063
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.2675 0.5271
Toxoplasma gondii FATC domain-containing protein 0.0035 0.0325 0.1442
Echinococcus granulosus dna polymerase kappa 0.0019 0.0016 0.0012
Echinococcus multilocularis Aminotransferase class III 0.0022 0.0065 0.0061
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0055 0.0722 0.6018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.1541 0.1537
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.1099 0.121
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0778 0.6337
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0063 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0471 0.0899
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Brugia malayi TAR-binding protein 0.021 0.3772 0.7431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0382 0.0722
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.1099 0.2141
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0276 0.5076 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.06 0.1173
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Brugia malayi beta-lactamase family protein 0.0074 0.1099 0.2166
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.1189 1
Schistosoma mansoni cpg binding protein 0.006 0.0821 0.0806
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Onchocerca volvulus 0.0074 0.1099 0.1167
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Toxoplasma gondii exonuclease III APE 0.0058 0.0778 0.3937
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.1099 0.121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Loa Loa (eye worm) hypothetical protein 0.0079 0.1189 0.2336
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.1541 0.1527
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.06 0.0595
Echinococcus granulosus Aminotransferase class III 0.0022 0.0065 0.0061
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0778 1
Mycobacterium ulcerans beta-lactamase 0.0074 0.1099 0.413
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0334 0.033
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0022 0.0065 0.0055
Mycobacterium tuberculosis Probable aminotransferase 0.0152 0.2639 0.2929
Loa Loa (eye worm) hypothetical protein 0.0019 0.0016 0.0023
Brugia malayi CXXC zinc finger family protein 0.006 0.0821 0.1618
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.1189 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Mycobacterium tuberculosis Conserved protein 0.0074 0.1099 0.121
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0022 0.0065 0.0049
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0064 0.0903 0.1779
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.06 0.1181
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.1189 1
Mycobacterium ulcerans hypothetical protein 0.0074 0.1099 0.413
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0022 0.0065 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Loa Loa (eye worm) beta-lactamase 0.0074 0.1099 0.2159
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0314 0.0618
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0016 0.0012
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0064 0.0903 0.7559
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.1879 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Leishmania major hypothetical protein, conserved 0.0074 0.1099 0.9232
Brugia malayi RNA binding protein 0.021 0.3772 0.7431
Schistosoma mansoni ap endonuclease 0.0058 0.0778 0.0763
Mycobacterium ulcerans lipase LipD 0.0074 0.1099 0.413
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1099 0.9232
Schistosoma mansoni hypothetical protein 0.0526 1 1
Echinococcus multilocularis ferritin 0.0052 0.0669 0.0664
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.1099 0.2141
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0073 0.1067 0.1063
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.1541 0.3036
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Brugia malayi RNA recognition motif domain containing protein 0.021 0.3772 0.7431
Toxoplasma gondii ABC1 family protein 0.0074 0.1099 0.5709
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.1541 0.1537
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.0019 0.0038
Schistosoma mansoni apoferritin-2 0.0052 0.0669 0.0654
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.06 0.0595
Mycobacterium ulcerans bacterioferritin BfrA 0.0052 0.0669 0.2488
Schistosoma mansoni cpg binding protein 0.0063 0.0888 0.0874
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0052 0.0669 0.0729
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0778 0.0773
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0028 0.0195 0.1523
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.1099 0.121
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Echinococcus multilocularis geminin 0.0526 1 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.1099 0.413
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0903 0.1753
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0064 0.0903 0.7559
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.0609 0.1171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0382 0.0722
Loa Loa (eye worm) hypothetical protein 0.0022 0.0063 0.0115
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0016 0.0012
Loa Loa (eye worm) CXXC zinc finger family protein 0.006 0.0821 0.161
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0778 0.649
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.1541 0.1537
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.1099 0.121
Plasmodium vivax hypothetical protein, conserved 0.0074 0.1099 0.9198
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0778 0.649
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0053 0.0676 0.3376
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.1099 0.9232
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.021 0.3772 0.7428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Echinococcus multilocularis expressed protein 0.0052 0.0669 0.0664
Leishmania major hypothetical protein, conserved 0.0079 0.1189 1
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Loa Loa (eye worm) hypothetical protein 0.0049 0.06 0.1173
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0034 0.0314 0.0309
Schistosoma mansoni fkbp-rapamycin associated protein 0.0019 0.0019 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0778 0.7246
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.1099 0.121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0276 0.5076 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0131 0.0978
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0127 0.2146 0.2134
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0494 0.0945
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Schistosoma mansoni hypothetical protein 0.0035 0.0334 0.0319
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0055 0.0722 0.6018
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0034 0.0314 0.2534
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0778 0.0851
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0016 0.0032
Echinococcus multilocularis serine protein kinase ATM 0.0035 0.0325 0.032
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0022 0.0065 0.0055
Schistosoma mansoni ferritin light chain 0.0052 0.0669 0.0654
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.1099 0.2141
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.3206 0.6305
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0778 0.649
Echinococcus granulosus GPCR family 2 0.0049 0.06 0.0595
Brugia malayi Latrophilin receptor protein 2 0.0049 0.06 0.1181
Loa Loa (eye worm) hypothetical protein 0.0074 0.1099 0.2159
Mycobacterium leprae Probable lipase LipE 0.0074 0.1099 0.4018
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0064 0.0903 0.0899
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.1099 0.2166
Schistosoma mansoni hypothetical protein 0.0049 0.06 0.0584
Echinococcus multilocularis GPCR, family 2 0.0049 0.06 0.0595
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.1099 0.2141
Mycobacterium ulcerans hypothetical protein 0.0152 0.2639 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0778 0.1524
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0035 0.0325 0.2629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.1099 0.121
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0064 0.0903 0.0888
Loa Loa (eye worm) TAR-binding protein 0.021 0.3772 0.7428
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.1099 0.1085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0064 0.0903 0.8438
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0778 0.649
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.1099 0.9232
Echinococcus granulosus ferritin 0.0052 0.0669 0.0664
Giardia lamblia GTOR 0.0064 0.0903 1
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0152 0.2639 0.5183
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.1715 0.3378
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.3398 0.6685
Schistosoma mansoni hypothetical protein 0.0073 0.1067 0.1053
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0778 1
Brugia malayi hypothetical protein 0.0079 0.1189 0.2343
Trichomonas vaginalis glucosylceramidase, putative 0.0191 0.3398 0.6685
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0034 0.0314 0.2534
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0035 0.0325 0.2629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0676 0.1304
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0778 0.0773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0495 0.0946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0722 0.1394
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0778 0.1505
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.1099 0.1095
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0474 0.8969 1
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Echinococcus multilocularis ornithine aminotransferase 0.0022 0.0065 0.0061
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.2675 0.5267
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0019 0.0019 0.0015
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.1189 0.6205
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0019 0.0019 0.0015
Echinococcus granulosus cpg binding protein 0.0063 0.0888 0.0884
Trichomonas vaginalis glucosylceramidase, putative 0.0276 0.5076 1
Schistosoma mansoni cpg binding protein 0.0063 0.0888 0.0874
Schistosoma mansoni ferritin 0.0052 0.0669 0.0654
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.2675 0.5271
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0064 0.0903 0.7559
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.1189 1
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0022 0.0065 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0778 0.1505
Echinococcus granulosus expressed protein 0.0052 0.0669 0.0664
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.1953 0.3842
Brugia malayi beta-lactamase 0.0074 0.1099 0.2166
Entamoeba histolytica hypothetical protein 0.0073 0.1067 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.1099 0.2159
Schistosoma mansoni transcription factor LCR-F1 0.0073 0.1067 0.1053
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0152 0.2639 0.2929
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.1953 0.3842
Loa Loa (eye worm) hypothetical protein 0.0105 0.1715 0.3372
Schistosoma mansoni tar DNA-binding protein 0.021 0.3772 0.3761
Schistosoma mansoni ferritin light chain 0.0052 0.0669 0.0654
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.0903 0.1753
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0074 0.0493
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0022 0.0065 0.0188
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0022 0.0065 0.0055
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0334 0.033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0314 0.0588

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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