Detailed information for compound 1003147

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 208.211 | Formula: C11H12O4
  • H donors: 1 H acceptors: 2 LogP: 2.44 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H]1OC(=O)c2c1ccc(c2O)OC
  • InChi: 1S/C11H12O4/c1-3-7-6-4-5-8(14-2)10(12)9(6)11(13)15-7/h4-5,7,12H,3H2,1-2H3/t7-/m0/s1
  • InChiKey: CJPMLOYFDLJAKU-ZETCQYMHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0108 0.0634 0.0634
Schistosoma mansoni hypothetical protein 0.0398 0.2863 0.2863
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0317 0.4055
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.012 0.012
Toxoplasma gondii rhodanese family domain-containing protein 0.0103 0.0597 1
Leishmania major 3-mercaptopyruvate sulfurtransferase 0.0103 0.0597 1
Schistosoma mansoni inositol monophosphatase 0.0042 0.0127 0.0127
Echinococcus granulosus Rhodanese 0.0103 0.0597 0.0597
Schistosoma mansoni alpha glucosidase 0.0042 0.012 0.012
Giardia lamblia Thiosulfate sulfurtransferase 0.0103 0.0597 1
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.012 0.2013
Echinococcus granulosus centrosomal protein of 41 kDa 0.0103 0.0597 0.0597
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0127 0.2129
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseB 0.0103 0.0597 1
Echinococcus granulosus intermediate filament protein 0.0032 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0103 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0092 0.0509 0.0509
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0103 0.0597 0.0597
Onchocerca volvulus 0.0536 0.3926 0.3926
Onchocerca volvulus 0.1325 1 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.019 0.019
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0317 0.0317
Onchocerca volvulus 0.0092 0.0509 0.0509
Mycobacterium leprae PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRAN 0.0103 0.0597 1
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.1325 1 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0149 0.0948 0.0948
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Entamoeba histolytica rodhanase-like domain containing protein 0.1325 1 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0187 0.1243 0.1243
Brugia malayi Thiosulfate sulfurtransferase D2023.5 0.0103 0.0597 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0597 0.0597
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0317 0.0317
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0149 0.0948 0.0948
Schistosoma mansoni lamin 0.0032 0.0049 0.0049
Schistosoma mansoni lipoxygenase 0.0091 0.0503 0.0503
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.012 0.012
Schistosoma mansoni microtubule-associated protein tau 0.0764 0.5681 0.5681
Entamoeba histolytica hypothetical protein, conserved 0.0103 0.0597 0.0597
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0401 0.2884 0.2884
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.1325 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.012 0.2013
Echinococcus multilocularis Rhodanese 0.0103 0.0597 0.0597
Plasmodium vivax mitogen-activated protein kinase phosphatase 1, putative 0.0103 0.0597 0.5
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.012 0.012
Echinococcus multilocularis neuropeptide s receptor 0.0532 0.3895 0.3895
Schistosoma mansoni lipoxygenase 0.0131 0.0805 0.0805
Trichomonas vaginalis cdc25b, putative 0.1325 1 1
Onchocerca volvulus 0.0103 0.0597 0.0597
Entamoeba histolytica hypothetical protein 0.0103 0.0597 0.0597
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.012 0.012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0127 0.2129
Echinococcus granulosus lysosomal alpha glucosidase 0.0187 0.1243 0.1243
Mycobacterium tuberculosis Conserved hypothetical protein 0.0103 0.0597 1
Brugia malayi Rhodanese-like domain containing protein 0.0103 0.0597 0.0597
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.0597 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0317 0.0317
Onchocerca volvulus 0.1325 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.019 0.019
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0127 0.0127
Echinococcus multilocularis lamin dm0 0.0032 0.0049 0.0049
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0149 0.0948 0.0948
Echinococcus granulosus heat shock protein 67b2 0.0103 0.0597 0.0597
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0049 0.0049
Trichomonas vaginalis cdc25c, putative 0.0103 0.0597 0.0597
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.012 0.012
Trypanosoma brucei mercaptopyruvate sulfurtransferase, putative 0.0103 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0044 0.0044
Mycobacterium leprae Conserved hypothetical protein 0.0103 0.0597 1
Echinococcus granulosus neuropeptide receptor A26 0.0532 0.3895 0.3895
Trypanosoma brucei glucosidase, putative 0.0042 0.012 0.2013
Echinococcus multilocularis centrosomal protein of 41 kDa 0.0103 0.0597 0.0597
Trichomonas vaginalis cdc25c, putative 0.1325 1 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0149 0.0948 0.0948
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.012 0.012
Brugia malayi Rhodanese-like domain containing protein 0.1325 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0317 0.4142
Plasmodium falciparum rhodanese like protein, putative 0.0103 0.0597 0.5
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0317 0.5321
Mycobacterium tuberculosis Conserved protein 0.0103 0.0597 1
Leishmania major As/Sb Reductase 0.0103 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.1221 0.9203 0.9203
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0401 0.2884 0.2884
Schistosoma mansoni ubiquitin-activating enzyme E1C 0.0103 0.0597 0.0597
Echinococcus granulosus 5'partial|tRNA 2 selenouridine synthase 0.0103 0.0597 0.0597
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0317 0.446
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA3 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0103 0.0597 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0149 0.0948 0.0948
Brugia malayi RIKEN cDNA 4930451A13 0.0103 0.0597 0.0597
Loa Loa (eye worm) thiosulfate sulfurtransferase 0.0103 0.0597 0.0597
Entamoeba histolytica rodhanase-like domain containing protein 0.0103 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0103 0.0597 0.0597
Entamoeba histolytica rodhanase-like domain containing protein 0.1325 1 1
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase CysA2 (rhodanese-like protein) (thiosulfate cyanide transsulfurase) (thiosulfate thiotran 0.0103 0.0597 1
Leishmania major hypothetical protein, conserved 0.0103 0.0597 1
Giardia lamblia Hypothetical protein 0.0103 0.0597 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0898 0.6711 0.6711
Mycobacterium ulcerans thiosulfate sulfurtransferase SseA 0.0103 0.0597 1
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0103 0.0597 0.0597
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.019 0.019
Entamoeba histolytica hypothetical protein 0.0103 0.0597 0.0597
Mycobacterium ulcerans thiosulfate sulfurtransferase, CysA2 0.0103 0.0597 1
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.1325 1 1
Schistosoma mansoni hypothetical protein 0.0103 0.0597 0.0597
Mycobacterium leprae Probable thiosulfate sulfurtransferase SseA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) 0.0103 0.0597 1
Onchocerca volvulus 0.1325 1 1
Schistosoma mansoni inositol monophosphatase 0.0042 0.0127 0.0127
Onchocerca volvulus 0.0032 0.0049 0.0049
Loa Loa (eye worm) inositol-1 0.0042 0.0127 0.0127
Mycobacterium leprae PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) 0.0103 0.0597 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0127 0.0145
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.1325 1 1
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.1325 1 1
Echinococcus multilocularis microtubule associated protein 2 0.0764 0.5681 0.5681
Brugia malayi Rhodanese-like domain containing protein 0.0103 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.1221 0.9203 0.9203
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0127 0.2129
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.1325 1 1
Leishmania major hypothetical protein, conserved 0.0103 0.0597 1
Onchocerca volvulus 0.0032 0.0049 0.0049
Entamoeba histolytica hypothetical protein 0.0103 0.0597 0.0597
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Schistosoma mansoni alpha-glucosidase 0.0161 0.1042 0.1042
Entamoeba histolytica rodhanase-like domain containing protein 0.0103 0.0597 0.0597
Schistosoma mansoni hypothetical protein 0.0398 0.2863 0.2863
Schistosoma mansoni alpha-glucosidase 0.0161 0.1042 0.1042
Loa Loa (eye worm) hypothetical protein 0.1325 1 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0187 0.1243 0.1243
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Brugia malayi MoeZ/MoeB domain containing protein 0.0103 0.0597 0.0597
Mycobacterium tuberculosis Probable thiosulfate sulfurtransferase SseA (rhodanese) (thiosulfate cyanide transsulfurase) (thiosulfate thiotransferase) 0.0103 0.0597 1
Echinococcus multilocularis tRNA 2 selenouridine synthase 0.0103 0.0597 0.0597
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.019 0.019
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0103 0.0597 0.0597
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.012 0.012
Echinococcus multilocularis musashi 0.0032 0.0049 0.0049
Echinococcus granulosus microtubule associated protein 2 0.0764 0.5681 0.5681
Entamoeba histolytica hypothetical protein 0.0103 0.0597 0.0597
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.1325 1 1
Brugia malayi Inositol-1 0.0042 0.0127 0.0127
Schistosoma mansoni intermediate filament proteins 0.0032 0.0049 0.0049
Brugia malayi intermediate filament protein 0.0032 0.0049 0.0049
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0317 0.4055
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.012 0.012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0317 0.4055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.019 0.019
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0317 0.0317
Schistosoma mansoni dual specificity protein phosphatase 0.0103 0.0597 0.0597
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.012 0.012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0049 0.0049
Echinococcus multilocularis L aminoadipate semialdehyde 0.0092 0.0509 0.0509
Leishmania major hypothetical protein, unknown function 0.0103 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0597 0.0597
Trypanosoma cruzi As/Sb Reductase, putative 0.0103 0.0597 1
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Echinococcus multilocularis neuropeptide receptor A26 0.0532 0.3895 0.3895
Trichomonas vaginalis thiosulfate sulfertansferase, putative 0.0103 0.0597 0.0597
Leishmania major hypothetical protein, conserved 0.0103 0.0597 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.019 0.019
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.012 0.012
Echinococcus granulosus lamin dm0 0.0032 0.0049 0.0049
Echinococcus multilocularis lysosomal alpha glucosidase 0.0187 0.1243 0.1243
Schistosoma mansoni ubiquitin-activating enzyme E1 0.0103 0.0597 0.0597
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0092 0.0509 0.0509
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0127 0.0127
Trypanosoma cruzi As/Sb Reductase, putative 0.0103 0.0597 1
Echinococcus granulosus lamin 0.0032 0.0049 0.0049
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Onchocerca volvulus 0.1325 1 1
Echinococcus granulosus m phase inducer phosphatasecdc25 0.1325 1 1
Brugia malayi hypothetical protein 0.0536 0.3926 0.3926
Mycobacterium ulcerans molybdopterin biosynthesis-like protein MoeZ 0.0103 0.0597 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0401 0.2884 0.2884
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0127 0.0127
Mycobacterium ulcerans hypothetical protein 0.0103 0.0597 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0401 0.2884 0.2884
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.012 0.012
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Plasmodium falciparum mitogen-activated protein kinase phosphatase 1, putative 0.0103 0.0597 0.5
Schistosoma mansoni Centrosomal protein of 41 kDa (Cep41 protein) (Testis-specificprotein A14 protein) 0.0103 0.0597 0.0597
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Trichomonas vaginalis cdc25a, putative 0.0103 0.0597 0.0597
Loa Loa (eye worm) hypothetical protein 0.0032 0.0049 0.0049
Trypanosoma cruzi mercaptopyruvate sulfurtransferase, putative 0.0103 0.0597 1
Giardia lamblia Hypothetical protein 0.0103 0.0597 1
Echinococcus granulosus L aminoadipate semialdehyde 0.0092 0.0509 0.0509
Loa Loa (eye worm) hypothetical protein 0.0536 0.3926 0.3926
Echinococcus granulosus geminin 0.0398 0.2863 0.2863
Mycobacterium tuberculosis Probable molybdenum cofactor biosynthesis protein MoeB2 (MPT-synthase sulfurylase) (molybdopterin synthase sulphurylase) 0.0103 0.0597 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0127 0.2129
Schistosoma mansoni hypothetical protein 0.0103 0.0597 0.0597
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0103 0.0597 0.0597
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0103 0.0597 1
Schistosoma mansoni hypothetical protein 0.0103 0.0597 0.0597
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0049 0.0049
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0401 0.2884 0.2884
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.019 0.019
Wolbachia endosymbiont of Brugia malayi sulfurtransferase 0.0103 0.0597 1
Loa Loa (eye worm) hypothetical protein 0.0103 0.0597 0.0597
Mycobacterium tuberculosis Possible transcriptional regulatory protein (possibly ArsR-family) 0.0103 0.0597 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0597 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0597 0.0597
Onchocerca volvulus 0.0103 0.0597 0.0597
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0149 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.1325 1 1
Entamoeba histolytica rodhanase-like domain containing protein 0.0103 0.0597 0.0597
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.012 0.012
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0103 0.0597 0.0597
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0149 0.0948 0.0948
Trypanosoma cruzi rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Trichomonas vaginalis Phage shock protein E precursor, putative 0.0103 0.0597 0.0597
Chlamydia trachomatis hypothetical protein 0.0103 0.0597 0.5
Schistosoma mansoni lamin 0.0032 0.0049 0.0049
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0092 0.0509 0.0509
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.012 0.012
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0131 0.0805 0.0805
Leishmania major hypothetical protein, conserved 0.0103 0.0597 1
Echinococcus granulosus neuropeptide s receptor 0.0532 0.3895 0.3895
Loa Loa (eye worm) hypothetical protein 0.0103 0.0597 0.0597
Leishmania major hypothetical protein, conserved 0.0103 0.0597 1
Entamoeba histolytica rodhanase-like domain containing protein 0.1325 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0597 0.0597
Leishmania major hypothetical protein, conserved 0.0103 0.0597 1
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.012 0.2013
Entamoeba histolytica hypothetical protein, conserved 0.0103 0.0597 0.0597
Echinococcus multilocularis geminin 0.0398 0.2863 0.2863
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0131 0.0805 0.0805
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.0597 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0127 0.0127
Giardia lamblia Dual specificity phosphatase Cdc25, putative 0.0103 0.0597 1
Trichomonas vaginalis cdc25b, putative 0.1325 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.012 0.012
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0103 0.0597 0.0597
Echinococcus multilocularis lamin 0.0032 0.0049 0.0049
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.019 0.019
Trypanosoma brucei rhodanese-like domain containing protein, putative 0.0103 0.0597 1
Plasmodium vivax rhodanese like protein, putative 0.0103 0.0597 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.019 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0597 0.0597
Brugia malayi Glycosyl hydrolases family 31 protein 0.0187 0.1243 0.1243
Echinococcus multilocularis heat shock protein 67b2 0.0103 0.0597 0.0597

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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