TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 620.197 | Formula: C15H20BrN5O13P2
H donors: 7 H acceptors: 10 LogP: -4.66 Rotable bonds: 0
Rule of 5 violations (Lipinski): 3
SMILES: O[C@@H]1[C@H]2COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4c5nc[n+]([C@@H]([C@@H]1O)O2)c(N)c5nc4Br)[C@@H]([C@@H]3O)O
InChi: 1S/C15H20BrN5O13P2/c16-15-19-6-11(17)20-3-18-12(6)21(15)14-10(25)8(23)5(33-14)2-31-36(28,29)34-35(26,27)30-1-4-7(22)9(24)13(20)32-4/h3-5,7-10,13-14,17,22-25H,1-2H2,(H2,26,27,28,29)/t4-,5-,7-,8-,9-,10-,13-,14-/m1/s1
InChiKey: WDGMEOAIDHHBSJ-AIKIOGRUSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	G protein coupled receptor 139	0.0023	0.0067	0.0067
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0177	0.2401	0.5583
Brugia malayi	Serotonin receptor	0.0023	0.0067	0.0155
Echinococcus granulosus	neuropeptide Y receptor	0.0023	0.0067	0.0067
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.014	0.1841	1
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0023	0.0067	0.0067
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0062	0.0657	0.1527
Echinococcus multilocularis	survival motor neuron protein 1	0.0232	0.3238	0.3238
Trypanosoma cruzi	major cysteine proteinase, putative	0.0041	0.0331	0.077
Echinococcus multilocularis	neuropeptide s receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0601	0.1398
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Trypanosoma cruzi	hypothetical protein, conserved	0.0038	0.0292	0.068
Entamoeba histolytica	cysteine proteinase, putative	0.0099	0.122	0.2998
Echinococcus multilocularis	microtubule associated protein 2	0.0678	1	1
Echinococcus multilocularis	tar DNA binding protein	0.0062	0.0657	0.0657
Brugia malayi	Dopamine receptor protein 2	0.0023	0.0067	0.0155
Echinococcus granulosus	tm gpcr rhodopsin	0.0023	0.0067	0.0067
Giardia lamblia	Cysteine protease	0.0041	0.0331	0.0814
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0041	0.0331	0.0175
Schistosoma mansoni	microtubule-associated protein tau	0.0678	1	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0023	0.0067	0.0067
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0041	0.0331	0.0175
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0386	0.0386
Loa Loa (eye worm)	acetyltransferase	0.0141	0.1848	0.4296
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0023	0.0067	0.0067
Mycobacterium ulcerans	lipase LipD	0.0038	0.0292	0.1588
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0023	0.0067	0.0155
Brugia malayi	Cathepsin L-like precursor	0.0127	0.1635	0.38
Brugia malayi	Cathepsin L-like precursor	0.0059	0.0601	0.1398
Brugia malayi	TAR-binding protein	0.0062	0.0657	0.1527
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0657	0.0657
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0023	0.0067	0.0155
Echinococcus granulosus	g protein coupled receptor	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin F-like cysteine peptidase	0.0041	0.0331	0.0814
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0122	0.1559	0.3625
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Plasmodium vivax	vivapain-2	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0303	0.4301	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Schistosoma mansoni	biogenic amine receptor	0.0023	0.0067	0.0067
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0041	0.0331	0.077
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0041	0.0331	0.0814
Brugia malayi	N-terminal motif family protein	0.0177	0.2401	0.5583
Loa Loa (eye worm)	hypothetical protein	0.0144	0.19	0.4418
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0038	0.0292	0.0856
Echinococcus granulosus	tar DNA binding protein	0.0062	0.0657	0.0657
Schistosoma mansoni	opsin-like receptor	0.0023	0.0067	0.0067
Onchocerca volvulus	Cathepsin L homolog	0.0041	0.0331	0.1078
Entamoeba histolytica	cysteine protease, putative	0.0041	0.0331	0.0814
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0041	0.0331	0.0331
Echinococcus granulosus	7TM GPCR rhodopsin	0.0023	0.0067	0.0067
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0657	0.0657
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0041	0.0331	0.0814
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0041	0.0331	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0185	0.2523	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0038	0.0292	0.0719
Onchocerca volvulus		0.0185	0.2523	1
Entamoeba histolytica	cysteine proteinase, putative	0.0185	0.2523	0.62
Brugia malayi	Papain family cysteine protease containing protein	0.0185	0.2523	0.5866
Onchocerca volvulus	Cathepsin L homolog	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0044	0.0386	0.0898
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus multilocularis	neuropeptide Y receptor	0.0023	0.0067	0.0067
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0041	0.0331	0.077
Trypanosoma cruzi	cysteine peptidase, putative	0.0059	0.0601	0.1398
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0386	0.0386
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0601	0.1398
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0292	0.068
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Plasmodium falciparum	serine repeat antigen 2	0.0041	0.0331	0.0193
Brugia malayi	neuropeptide F receptor	0.0023	0.0067	0.0155
Schistosoma mansoni	biogenic amine receptor	0.0023	0.0067	0.0067
Mycobacterium ulcerans	beta-lactamase	0.0038	0.0292	0.1588
Brugia malayi	hypothetical protein	0.0232	0.3238	0.7527
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0127	0.1635	0.4017
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0067	0.0067
Giardia lamblia	Cathepsin B precursor	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	Melatonin receptor type 1A	0.0023	0.0067	0.0155
Schistosoma mansoni	neuropeptide receptor	0.0023	0.0067	0.0067
Giardia lamblia	Cathepsin L precursor	0.0041	0.0331	0.0814
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0185	0.2523	0.62
Brugia malayi	beta-lactamase family protein	0.0038	0.0292	0.068
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0041	0.0331	0.0331
Giardia lamblia	Cathepsin B-like cysteine proteinase 3 precursor	0.0041	0.0331	0.0814
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0303	0.4301	0.4301
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0041	0.0331	0.0331
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0041	0.0331	0.0814
Brugia malayi	Cathepsin L-like precursor	0.0185	0.2523	0.5866
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Entamoeba histolytica	cysteine protease, putative	0.0185	0.2523	0.62
Toxoplasma gondii	histone lysine acetyltransferase GCN5-B	0.0041	0.034	0.0215
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.014	0.1841	1
Echinococcus multilocularis	serotonin receptor	0.0144	0.19	0.19
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.006	0.0618	0.2448
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0303	0.4301	0.4301
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0292	0.068
Schistosoma mansoni	opsin-like receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0303	0.4301	0.4301
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	hypothetical protein	0.0023	0.0067	0.0067
Onchocerca volvulus		0.0041	0.0331	0.1078
Giardia lamblia	Cysteine protease	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1635	0.38
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Plasmodium vivax	unspecified product	0.0059	0.0601	0.1384
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0041	0.0331	0.0175
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0331	0.0814
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Giardia lamblia	Cathepsin B precursor	0.0122	0.1559	0.3831
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.006	0.0618	0.0618
Echinococcus granulosus	cathepsin L cysteine protease	0.0099	0.122	0.122
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0023	0.0067	0.0067
Schistosoma mansoni	hypothetical protein	0.0047	0.0432	0.0432
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0041	0.0331	0.0193
Entamoeba histolytica	cysteine proteinase, putative	0.0127	0.1635	0.4017
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	G protein coupled receptor 139	0.0023	0.0067	0.0067
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0185	0.2523	0.2523
Entamoeba histolytica	cysteine protease, putative	0.0041	0.0331	0.0814
Echinococcus multilocularis	allatostatin A receptor	0.0023	0.0067	0.0067
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0041	0.0331	0.0175
Schistosoma mansoni	cathepsin s	0.0059	0.0601	0.0601
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0386	0.0386
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Giardia lamblia	Cathepsin B precursor	0.0122	0.1559	0.3831
Entamoeba histolytica	cysteine protease, putative	0.0041	0.0331	0.0814
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Echinococcus granulosus	sex peptide receptor	0.0023	0.0067	0.0067
Plasmodium falciparum	serine repeat antigen 1	0.0041	0.0331	0.0193
Onchocerca volvulus		0.0185	0.2523	1
Echinococcus granulosus	cysteine protease	0.0099	0.122	0.122
Toxoplasma gondii	aldehyde dehydrogenase	0.006	0.0618	0.1458
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0331	0.077
Onchocerca volvulus	Cathepsin L homolog	0.0185	0.2523	1
Trichomonas vaginalis	bromodomain-containing protein, putative	0.0041	0.034	0.0837
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0023	0.0067	0.0067
Schistosoma mansoni	hypothetical protein	0.0033	0.022	0.022
Loa Loa (eye worm)	RNA binding protein	0.0062	0.0657	0.1527
Brugia malayi	cathepsin L-like cysteine proteinase	0.0041	0.0331	0.077
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Loa Loa (eye worm)	ctsf protein	0.0185	0.2523	0.5866
Schistosoma mansoni	adenoreceptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0023	0.0067	0.0067
Giardia lamblia	Hypothetical protein	0.0041	0.0331	0.0814
Onchocerca volvulus	Cathepsin F homolog	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0331	0.077
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0127	0.1635	0.38
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0185	0.2523	1
Onchocerca volvulus		0.0185	0.2523	1
Echinococcus multilocularis	fmrfamide receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	neuropeptide receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0041	0.0331	0.0814
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0023	0.0067	0.0067
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0023	0.0067	0.0067
Toxoplasma gondii	cathepsin B	0.0122	0.1559	0.5678
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0041	0.0331	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	GnHR receptor homolog	0.0023	0.0067	0.0155
Echinococcus multilocularis	neuropeptide receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0041	0.0331	0.0331
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.014	0.1841	0.5387
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0099	0.122	0.4169
Entamoeba histolytica	hypothetical protein	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.006	0.0618	0.1808
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	7tm_1 domain containing protein	0.0023	0.0067	0.0067
Schistosoma mansoni	amine GPCR	0.0352	0.5055	0.5055
Loa Loa (eye worm)	hypothetical protein	0.0033	0.022	0.0512
Giardia lamblia	Histone acetyltransferase GCN5	0.0038	0.0288	0.0708
Giardia lamblia	Cathepsin L-like protease	0.0041	0.0331	0.0814
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0023	0.0067	0.0067
Loa Loa (eye worm)	fibroinase	0.0185	0.2523	0.5866
Treponema pallidum	fructose-bisphosphate aldolase	0.0287	0.407	0.5
Onchocerca volvulus		0.0185	0.2523	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0185	0.2523	0.2523
Trichomonas vaginalis	penicillin-binding protein, putative	0.0038	0.0292	0.0719
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	putative neuropeptide receptor NPR1	0.0023	0.0067	0.0155
Echinococcus granulosus	neuropeptide s receptor	0.0023	0.0067	0.0067
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0041	0.0331	0.0814
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0122	0.1559	0.6179
Echinococcus granulosus	biogenic amine 5HT receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	cathepsin L	0.0099	0.122	0.122
Echinococcus granulosus	fmrfamide receptor	0.0023	0.0067	0.0067
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Echinococcus granulosus	allatostatin A receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0044	0.0386	0.0898
Giardia lamblia	Cathepsin L precursor	0.0041	0.0331	0.0814
Loa Loa (eye worm)	TYRA-2 protein	0.0023	0.0067	0.0155
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0023	0.0067	0.0067
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0618	0.3356
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0099	0.122	0.122
Plasmodium vivax	histone acetyltransferase GCN5, putative	0.0041	0.034	0.0215
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0023	0.0067	0.0067
Trichomonas vaginalis	conserved hypothetical protein	0.0041	0.0331	0.0814
Echinococcus granulosus	orexin receptor type 2	0.0023	0.0067	0.0067
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0023	0.0067	0.0067
Toxoplasma gondii	cathepsin CPC2	0.0041	0.0331	0.0175
Brugia malayi	G-protein coupled receptor	0.0023	0.0067	0.0155
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0023	0.0067	0.0067
Trypanosoma cruzi	cruzipain precursor, putative	0.0059	0.0601	0.1398
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0041	0.0331	0.0331
Mycobacterium ulcerans	esterase/lipase LipP	0.0038	0.0292	0.1588
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0041	0.0331	0.077
Brugia malayi	Papain family cysteine protease containing protein	0.0041	0.0331	0.077
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0041	0.0331	0.077
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Schistosoma mansoni	opsin-like receptor	0.0023	0.0067	0.0067
Giardia lamblia	Encystation-specific protease	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	beta LACTamase domain containing family member	0.0038	0.0292	0.0292
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus multilocularis	g protein coupled receptor	0.0023	0.0067	0.0067
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0041	0.0331	0.0175
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0023	0.0067	0.0067
Trypanosoma cruzi	cysteine peptidase, putative	0.0185	0.2523	0.5866
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0038	0.0292	0.068
Giardia lamblia	Cathepsin L precursor	0.0041	0.0331	0.0814
Schistosoma mansoni	myosin xvIII	0.0023	0.0067	0.0067
Brugia malayi	Cathepsin L-like precursor	0.0185	0.2523	0.5866
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0041	0.0331	0.0814
Schistosoma mansoni	survival motor neuron protein	0.0047	0.0432	0.0432
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0023	0.0067	0.0155
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0044	0.0386	0.0386
Giardia lamblia	Cathepsin B precursor	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0331	0.077
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0099	0.122	0.122
Trichomonas vaginalis	D-aminoacylase, putative	0.0038	0.0292	0.0719
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	cathepsin L	0.0041	0.0331	0.0331
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0047	0.0432	0.1003
Echinococcus granulosus	tm gpcr rhodopsin	0.0023	0.0067	0.0067
Echinococcus multilocularis	neuropeptide Y receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Brugia malayi	putative neuropeptide receptor	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Loa Loa (eye worm)	melatonin receptor type 1A	0.0023	0.0067	0.0155
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0023	0.0067	0.0067
Mycobacterium tuberculosis	Probable lipase LipD	0.0038	0.0292	0.0856
Trypanosoma cruzi	major cysteine proteinase, putative	0.0041	0.0331	0.077
Brugia malayi	AKH receptor	0.0023	0.0067	0.0155
Schistosoma mansoni	cathepsin C	0.0041	0.0331	0.0331
Echinococcus granulosus	cathepsin l1	0.0127	0.1635	0.1635
Brugia malayi	G protein-coupled receptor	0.0023	0.0067	0.0155
Leishmania major	hypothetical protein, conserved	0.0038	0.0292	0.1159
Echinococcus granulosus	neuropeptide receptor	0.0023	0.0067	0.0067
Plasmodium vivax	serine-repeat antigen (SERA)	0.0041	0.0331	0.0175
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0177	0.2401	0.9503
Entamoeba histolytica	cysteine protease, putative	0.0041	0.0331	0.0814
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0455	0.1058
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Echinococcus multilocularis	cathepsin b	0.0303	0.4301	0.4301
Brugia malayi	follicle stimulating hormone receptor	0.0023	0.0067	0.0155
Brugia malayi	Cathepsin L-like precursor	0.0185	0.2523	0.5866
Loa Loa (eye worm)	hypothetical protein	0.0185	0.2523	0.5866
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	hypothetical protein	0.0023	0.0067	0.0067
Giardia lamblia	Cathepsin B precursor	0.0041	0.0331	0.0814
Giardia lamblia	Fructose-bisphosphate aldolase	0.0287	0.407	1
Toxoplasma gondii	histone lysine acetyltransferase GCN5-A	0.0041	0.034	0.0215
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0657	0.0657
Plasmodium falciparum	dipeptidyl aminopeptidase 1	0.0041	0.0331	0.0193
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0023	0.0067	0.0067
Plasmodium falciparum	serine repeat antigen 5	0.0041	0.0331	0.0193
Brugia malayi	acetyltransferase, GNAT family protein	0.0141	0.1848	0.4296
Schistosoma mansoni	cathepsin S (C01 family)	0.0041	0.0331	0.0331
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0041	0.0331	0.0175
Echinococcus granulosus	neuropeptide Y receptor	0.0023	0.0067	0.0067
Brugia malayi	fibroinase precursor	0.0041	0.0331	0.077
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Mycobacterium tuberculosis	Probable lipase LipE	0.0038	0.0292	0.0856
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus granulosus	tm gpcr rhodopsin	0.0023	0.0067	0.0067
Giardia lamblia	Hypothetical protein	0.0041	0.0331	0.0814
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0127	0.1635	0.4017
Schistosoma mansoni	histamine h1 receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0122	0.1559	0.1559
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0038	0.0292	0.0292
Plasmodium falciparum	dipeptidyl aminopeptidase 2	0.0041	0.0331	0.0193
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase	0.0041	0.0331	0.0814
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Onchocerca volvulus		0.0038	0.0292	0.092
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0041	0.0331	0.0814
Brugia malayi	G protein-coupled receptor F59B2.13	0.0023	0.0067	0.0155
Echinococcus multilocularis	gcn5proteinral control of amino acid synthesis	0.0141	0.1848	0.1848
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Schistosoma mansoni	hypothetical protein	0.0166	0.2236	0.2236
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.0618	0.0618
Loa Loa (eye worm)	G-protein coupled receptor	0.0023	0.0067	0.0155
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0038	0.0292	0.0856
Entamoeba histolytica	cysteine proteinase, putative	0.0099	0.122	0.2998
Brugia malayi	cathepsin L-like precursor	0.0127	0.1635	0.38
Echinococcus granulosus	g protein coupled receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0023	0.0067	0.0067
Brugia malayi	neuropeptide F receptor	0.0023	0.0067	0.0155
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0185	0.2523	0.2523
Entamoeba histolytica	acetyltransferase, GNAT family	0.0038	0.0288	0.0708
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Brugia malayi	Papain family cysteine protease containing protein	0.0041	0.0331	0.077
Trichomonas vaginalis	cat eye syndrome critical region protein 2, cscr2, putative	0.0041	0.034	0.0837
Trypanosoma cruzi	cysteine proteinase, putative	0.0099	0.122	0.2836
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0099	0.122	0.2836
Schistosoma mansoni	amine GPCR	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus granulosus	g protein coupled receptor	0.0023	0.0067	0.0067
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	D-aminoacylase, putative	0.0038	0.0292	0.0719
Brugia malayi	Dopamine receptor	0.0023	0.0067	0.0155
Brugia malayi	ORL1-like opioid receptor	0.0023	0.0067	0.0155
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0292	0.068
Echinococcus granulosus	neuropeptide receptor	0.0023	0.0067	0.0067
Giardia lamblia	Cysteine protease	0.0041	0.0331	0.0814
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0137	0.1788	0.1788
Schistosoma mansoni	hypothetical protein	0.0166	0.2236	0.2236
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0122	0.1559	0.6179
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0023	0.0067	0.0067
Plasmodium vivax	unspecified product	0.0041	0.0331	0.0175
Entamoeba histolytica	cysteine protease, putative	0.0041	0.0331	0.0814
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0041	0.0331	0.0331
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0122	0.1559	0.3831
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0023	0.0067	0.0067
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0041	0.0331	0.0175
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus granulosus	neuropeptide receptor A26	0.0023	0.0067	0.0067
Echinococcus multilocularis	g-protein coupled receptor	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Loa Loa (eye worm)	cysteine protease	0.0185	0.2523	0.5866
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0292	0.068
Plasmodium vivax	vivapain-1	0.0099	0.122	0.4158
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0041	0.0331	0.077
Echinococcus multilocularis	fmrfamide receptor	0.0023	0.0067	0.0067
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Giardia lamblia	Cysteine protease	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0232	0.3238	0.7527
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0099	0.122	0.2998
Brugia malayi	larval opioid receptor	0.0023	0.0067	0.0155
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0455	0.1058
Brugia malayi	Serotonin receptor	0.0023	0.0067	0.0155
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0023	0.0067	0.0067
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.006	0.0618	0.0618
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0059	0.0601	0.1398
Brugia malayi	cathepsin F-like cysteine proteinase	0.0041	0.0331	0.077
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0041	0.0331	0.0175
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0657	0.0657
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Echinococcus granulosus	neuropeptides capa receptor	0.0023	0.0067	0.0067
Giardia lamblia	Cathepsin L precursor	0.0041	0.0331	0.0814
Mycobacterium tuberculosis	Probable hydrolase	0.0038	0.0292	0.0856
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0041	0.0331	0.077
Entamoeba histolytica	cysteine proteinase, putative	0.0099	0.122	0.2998
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus granulosus	dro:myosuppressin receptor	0.0023	0.0067	0.0067
Toxoplasma gondii	cathepsin CPL	0.0185	0.2523	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0023	0.0067	0.0067
Trypanosoma cruzi	cysteine peptidase, putative	0.0185	0.2523	0.5866
Echinococcus multilocularis	cathepsin L	0.0099	0.122	0.122
Giardia lamblia	Cathepsin L-like protease	0.0041	0.0331	0.0814
Schistosoma mansoni	biogenic amine receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2	0.0141	0.1848	0.1848
Mycobacterium tuberculosis	Probable esterase LipL	0.0038	0.0292	0.0856
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0618	0.3356
Trypanosoma cruzi	cysteine proteinase, putative	0.0099	0.122	0.2836
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0185	0.2523	0.2523
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Echinococcus granulosus	g-protein coupled receptor	0.0023	0.0067	0.0067
Giardia lamblia	Cathepsin B precursor	0.0122	0.1559	0.3831
Schistosoma mansoni	growth hormone secretagogue receptor	0.0023	0.0067	0.0067
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0041	0.0331	0.0175
Trypanosoma cruzi	cysteine peptidase, putative	0.0185	0.2523	0.5866
Schistosoma mansoni	tar DNA-binding protein	0.0062	0.0657	0.0657
Schistosoma mansoni	hypothetical protein	0.0023	0.0067	0.0067
Echinococcus granulosus	neuropeptide FF receptor 2	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0041	0.0331	0.0814
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Brugia malayi	RE15519p	0.0023	0.0067	0.0155
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0023	0.0067	0.0155
Leishmania major	cysteine peptidase A (CPA)	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.0618	0.3356
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0023	0.0067	0.0067
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0455	0.1058
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0127	0.1635	0.38
Schistosoma mansoni	cathepsin F (C01 family)	0.0185	0.2523	0.2523
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0099	0.122	0.122
Loa Loa (eye worm)	G-protein coupled receptor	0.0023	0.0067	0.0155
Echinococcus multilocularis	neuropeptides capa receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	cathepsin L cysteine protease	0.0185	0.2523	0.2523
Echinococcus granulosus	biogenic amine 5HT receptor	0.0144	0.19	0.19
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0331	0.077
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Schistosoma mansoni	amine GPCR	0.0023	0.0067	0.0067
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0059	0.0601	0.1398
Schistosoma mansoni	hypothetical protein	0.0023	0.0067	0.0067
Plasmodium falciparum	serine repeat antigen 7	0.0041	0.0331	0.0193
Echinococcus multilocularis	g protein coupled receptor	0.0023	0.0067	0.0067
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0303	0.4301	1
Schistosoma mansoni	hypothetical protein	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1635	0.38
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Echinococcus multilocularis	geminin	0.0166	0.2236	0.2236
Echinococcus granulosus	cathepsin l1	0.0185	0.2523	0.2523
Plasmodium falciparum	serine repeat antigen 6	0.0041	0.0331	0.0193
Echinococcus multilocularis	orexin receptor type 2	0.0023	0.0067	0.0067
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Brugia malayi	Papain family cysteine protease containing protein	0.0099	0.122	0.2836
Echinococcus multilocularis	cathepsin L	0.0041	0.0331	0.0331
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0185	0.2523	0.5866
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0038	0.0292	0.1588
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0023	0.0067	0.0067
Echinococcus granulosus	cathepsin b	0.0303	0.4301	0.4301
Mycobacterium tuberculosis	Conserved protein	0.0038	0.0292	0.0856
Onchocerca volvulus		0.0038	0.0292	0.092
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0185	0.2523	0.5866
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0185	0.2523	0.2523
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0041	0.0331	0.0814
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0099	0.122	0.2998
Brugia malayi	Cathepsin L-like precursor	0.0185	0.2523	0.5866
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0023	0.0067	0.0067
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0023	0.0067	0.0067
Trypanosoma cruzi	cysteine peptidase, putative	0.0185	0.2523	0.5866
Echinococcus granulosus	cathepsin b	0.0303	0.4301	0.4301
Brugia malayi	RNA binding protein	0.0062	0.0657	0.1527
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Giardia lamblia	Cathepsin B precursor	0.0041	0.0331	0.0814
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.0618	0.0618
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Brugia malayi	cathepsin F-like cysteine proteinase	0.0059	0.0601	0.1398
Giardia lamblia	Cathepsin B precursor	0.0041	0.0331	0.0814
Echinococcus multilocularis	sex peptide receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	serotonin receptor	0.0144	0.19	0.19
Trichomonas vaginalis	penicillin-binding protein, putative	0.0038	0.0292	0.0719
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Entamoeba histolytica	cysteine proteinase, putative	0.0185	0.2523	0.62
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0099	0.122	0.4835
Onchocerca volvulus		0.0185	0.2523	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	dro:myosuppressin receptor	0.0023	0.0067	0.0067
Entamoeba histolytica	cysteine protease, putative	0.0041	0.0331	0.0814
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0023	0.0067	0.0067
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0041	0.0331	0.0814
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0023	0.0067	0.0155
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0386	0.0386
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0185	0.2523	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.022	0.0512
Loa Loa (eye worm)	cathepsin B	0.0122	0.1559	0.3625
Loa Loa (eye worm)	neuropeptide F receptor	0.0023	0.0067	0.0155
Brugia malayi	Cathepsin L-like precursor	0.0127	0.1635	0.38
Trypanosoma brucei	hypothetical protein, conserved	0.0038	0.0292	0.1159
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0041	0.0331	0.0814
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin H-like cysteine peptidase	0.0041	0.0331	0.0814
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Brugia malayi	RNA recognition motif domain containing protein	0.0062	0.0657	0.1527
Onchocerca volvulus		0.0185	0.2523	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0023	0.0067	0.0155
Trypanosoma cruzi	cysteine peptidase, putative	0.0099	0.122	0.2836
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0287	0.407	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0044	0.0386	0.0386
Loa Loa (eye worm)	hypothetical protein	0.0144	0.19	0.4418
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0038	0.0292	0.0856
Echinococcus granulosus	somatostatin receptor	0.0023	0.0067	0.0067
Echinococcus granulosus	neuropeptides capa receptor	0.0023	0.0067	0.0067
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0303	0.4301	0.4301
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0041	0.0331	0.0814
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0099	0.122	0.4835
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0041	0.0331	0.0814
Echinococcus multilocularis	cysteine protease	0.0185	0.2523	0.2523
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0041	0.0331	0.0814
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.407	1
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Brugia malayi	Papain family cysteine protease containing protein	0.0099	0.122	0.2836
Onchocerca volvulus		0.0185	0.2523	1
Loa Loa (eye worm)	TAR-binding protein	0.0062	0.0657	0.1527
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Echinococcus granulosus	histone acetyltransferase KAT2B	0.0041	0.034	0.034
Plasmodium falciparum	serine repeat antigen 3	0.0041	0.0331	0.0193
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0455	0.1058
Brugia malayi	sulfakinin receptor protein	0.0023	0.0067	0.0155
Brugia malayi	G-protein coupled receptor	0.0023	0.0067	0.0155
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Brugia malayi	Papain family cysteine protease containing protein	0.0041	0.0331	0.077
Trypanosoma cruzi	cruzipain precursor, putative	0.0185	0.2523	0.5866
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0038	0.0292	0.0292
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0185	0.2523	0.62
Echinococcus granulosus	survival motor neuron protein 1	0.0232	0.3238	0.3238
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0041	0.0331	0.0814
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0292	0.068
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0023	0.0067	0.0155
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0023	0.0067	0.0155
Entamoeba histolytica	cysteine proteinase, putative	0.0099	0.122	0.2998
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus multilocularis	cysteine protease	0.0185	0.2523	0.2523
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0244	0.3417	1
Mycobacterium ulcerans	hypothetical protein	0.0038	0.0292	0.1588
Echinococcus multilocularis	cathepsin L cysteine protease	0.0185	0.2523	0.2523
Loa Loa (eye worm)	hypothetical protein	0.0059	0.0601	0.1398
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0023	0.0067	0.0067
Brugia malayi	beta-lactamase family protein	0.0038	0.0292	0.068
Echinococcus granulosus	geminin	0.0166	0.2236	0.2236
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Loa Loa (eye worm)	hypothetical protein	0.0127	0.1635	0.38
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0038	0.0292	0.0292
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Plasmodium falciparum	serine repeat antigen 8	0.0041	0.0331	0.0193
Toxoplasma gondii	cathepsin CPC1	0.0041	0.0331	0.0175
Entamoeba histolytica	cysteine proteinase 1, putative	0.0099	0.122	0.2998
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Mycobacterium tuberculosis	Conserved protein	0.0038	0.0292	0.0856
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0185	0.2523	0.62
Mycobacterium tuberculosis	Conserved protein	0.0038	0.0292	0.0856
Brugia malayi	Cathepsin L-like precursor	0.0185	0.2523	0.5866
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0023	0.0067	0.0067
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0144	0.19	0.19
Giardia lamblia	Cathepsin L precursor	0.0041	0.0331	0.0814
Schistosoma mansoni	amine GPCR	0.0023	0.0067	0.0067
Giardia lamblia	Cathepsin L precursor	0.0041	0.0331	0.0814
Entamoeba histolytica	cysteine protease, putative	0.0099	0.122	0.2998
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0331	0.077
Trypanosoma cruzi	cysteine protease, putative	0.0099	0.122	0.2836
Brugia malayi	hypothetical protein	0.0023	0.0067	0.0155
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus multilocularis	somatostatin receptor	0.0023	0.0067	0.0067
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0041	0.0331	0.0814
Echinococcus multilocularis	g protein coupled receptor	0.0023	0.0067	0.0067
Onchocerca volvulus		0.0047	0.0432	0.1486
Plasmodium falciparum	serine repeat antigen 9	0.0041	0.0331	0.0193
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0041	0.0331	0.0814
Brugia malayi	cathepsin B-like cysteine proteinase	0.0303	0.4301	1
Schistosoma mansoni	amine GPCR	0.0023	0.0067	0.0067
Brugia malayi	Dopamine receptor protein 1	0.0023	0.0067	0.0155
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0041	0.0331	0.0175
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0023	0.0067	0.0067
Trichomonas vaginalis	esterase, putative	0.0038	0.0292	0.0719
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0287	0.407	1
Brugia malayi	cathepsin L precursor	0.0041	0.0331	0.077
Loa Loa (eye worm)	beta-lactamase	0.0038	0.0292	0.068
Plasmodium vivax	vivapain-2	0.0185	0.2523	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0023	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or H-like cysteine peptidase	0.0041	0.0331	0.0814
Brugia malayi	beta-lactamase	0.0038	0.0292	0.068
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0038	0.0292	0.068
Schistosoma mansoni	cathepsin B (C01 family)	0.0041	0.0331	0.0331
Echinococcus multilocularis	neuropeptide receptor A26	0.0023	0.0067	0.0067
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0044	0.0386	0.0386
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0041	0.0331	0.0331
Onchocerca volvulus		0.0127	0.1635	0.6383
Schistosoma mansoni	cathepsin F (C01 family)	0.0127	0.1635	0.1635
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0067	0.0155
Echinococcus granulosus	serotonin receptor	0.0023	0.0067	0.0067
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0041	0.0331	0.0175
Leishmania major	cathepsin L-like protease	0.0185	0.2523	1
Plasmodium vivax	vivapain-3	0.0099	0.122	0.4158
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0292	0.068
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0023	0.0067	0.0067
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0331	0.077
Brugia malayi	Cathepsin L-like precursor	0.0185	0.2523	0.5866
Schistosoma mansoni	neuropeptide f receptor 76f	0.0023	0.0067	0.0067
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0023	0.0067	0.0155
Entamoeba histolytica	cysteine proteinase 2	0.0099	0.122	0.2998
Plasmodium falciparum	serine repeat antigen 4	0.0041	0.0331	0.0193
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0023	0.0067	0.0067
Onchocerca volvulus		0.0038	0.0292	0.092
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0023	0.0067	0.0067
Trypanosoma cruzi	hypothetical protein, conserved	0.0038	0.0292	0.068
Plasmodium vivax	unspecified product	0.0099	0.122	0.4158
Plasmodium vivax	serine-repeat antigen (SERA)	0.0041	0.0331	0.0175
Echinococcus multilocularis	cathepsin b	0.0303	0.4301	0.4301
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0185	0.2523	0.62
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0185	0.2523	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3350986

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1009539