Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0134 | 0.0566 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0306 | 0.6751 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Treponema pallidum | DNA ligase (lig) | 0.0032 | 0.0306 | 0.5 |
Trypanosoma cruzi | metacaspase, putative | 0.0031 | 0.0294 | 0.3803 |
Echinococcus granulosus | sentrin specific protease 7 | 0.017 | 0.1973 | 0.3922 |
Onchocerca volvulus | 0.0014 | 0.0099 | 0.0182 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0017 | 0.0134 | 0.3657 |
Onchocerca volvulus | 0.0049 | 0.0515 | 0.0949 | |
Echinococcus multilocularis | caspase 2 | 0.0031 | 0.0294 | 0.028 |
Onchocerca volvulus | 0.0014 | 0.0099 | 0.0182 | |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0099 | 0.0182 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0422 | 0.5007 | 0.5 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.0134 | 0.0566 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.0134 | 0.0239 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Trypanosoma cruzi | hypothetical protein | 0.0015 | 0.0105 | 0.1045 |
Brugia malayi | hypothetical protein | 0.0456 | 0.5429 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.006 | 0.065 | 0.8997 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0099 | 0.0182 |
Echinococcus granulosus | protein quaking | 0.0028 | 0.0264 | 0.0499 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.068 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0134 | 0.0247 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0303 | 0.0578 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Leishmania major | SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative | 0.0015 | 0.0105 | 0.0094 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.0134 | 0.0247 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0342 | 0.4413 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0134 | 0.0239 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0014 | 0.0099 | 0.0169 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0049 | 0.0515 | 0.727 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0424 | 0.0821 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0451 | 1 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0031 | 0.0294 | 0.0559 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0718 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0515 | 0.6716 |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.017 | 0.1973 | 0.3922 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0012 | 0.0065 | 0.012 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0385 | 0.0742 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C48, putative | 0.0015 | 0.0105 | 0.1045 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0303 | 0.0578 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0032 | 0.0306 | 0.0585 |
Schistosoma mansoni | patched 1 | 0.0044 | 0.0451 | 0.0874 |
Echinococcus granulosus | expressed conserved protein | 0.0155 | 0.1794 | 0.3564 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0492 | 0.0478 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0264 | 0.0499 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Trichomonas vaginalis | sentrin/sumo-specific protease, senp8, putative | 0.0015 | 0.0105 | 0.2205 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0134 | 0.0566 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0264 | 0.0486 |
Brugia malayi | DKFZp564C0469 protein | 0.0032 | 0.0306 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.5429 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Echinococcus multilocularis | caspase | 0.0114 | 0.1301 | 0.1289 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0031 | 0.0294 | 0.3803 |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0105 | 0.0193 |
Onchocerca volvulus | 0.003 | 0.0283 | 0.0521 | |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0101 | 0.1149 | 0.5753 |
Plasmodium falciparum | sentrin-specific protease 1 | 0.0015 | 0.0105 | 0.2858 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0718 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0294 | 0.6462 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0014 | 0.0099 | 0.0397 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0515 | 0.0949 |
Trypanosoma cruzi | metacaspase, putative | 0.0031 | 0.0294 | 0.3803 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0134 | 0.0247 |
Onchocerca volvulus | 0.0032 | 0.0306 | 0.0565 | |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0009 | 0.0033 | 0.0901 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0009 | 0.0033 | 0.0061 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0014 | 0.0099 | 0.0169 |
Mycobacterium ulcerans | hypothetical protein | 0.0049 | 0.0515 | 0.7157 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0009 | 0.0033 | 0.0037 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.068 | 1 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0014 | 0.0099 | 0.0397 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0065 | 0.012 |
Plasmodium vivax | unspecified product | 0.0009 | 0.0033 | 0.0901 |
Loa Loa (eye worm) | Ulp1 protease | 0.0015 | 0.0105 | 0.0193 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0134 | 0.0247 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0049 | 0.0515 | 0.727 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0193 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0032 | 0.0306 | 0.399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0105 | 0.2205 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0035 | 0.0064 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0369 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.2274 | 0.4525 |
Onchocerca volvulus | 0.0014 | 0.0099 | 0.0182 | |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0114 | 0.1301 | 0.2577 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0134 | 0.052 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0014 | 0.0099 | 0.0182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0718 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.0134 | 0.0239 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.068 | 1 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0032 | 0.0306 | 0.8373 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0432 | 0.0836 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0515 | 0.0949 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0385 | 0.4614 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0492 | 0.0957 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0515 | 0.2485 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0385 | 0.8513 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0369 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0294 | 0.6462 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0303 | 0.0289 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0031 | 0.0294 | 0.4317 |
Trypanosoma brucei | SUMO1/Ulp2, putative | 0.0015 | 0.0105 | 0.1045 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0385 | 0.4918 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0134 | 0.3657 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0032 | 0.0306 | 0.0565 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0303 | 0.0578 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0492 | 0.0907 |
Echinococcus multilocularis | protein quaking | 0.0028 | 0.0264 | 0.025 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0515 | 0.6716 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0154 | 0.1782 | 0.177 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0424 | 0.2018 |
Plasmodium falciparum | metacaspase 1 | 0.0031 | 0.0294 | 0.8022 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.0718 | 1 |
Echinococcus granulosus | sentrin specific protease 8 | 0.0015 | 0.0105 | 0.0181 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0014 | 0.0099 | 0.0397 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0306 | 0.6751 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0015 | 0.0105 | 0.1538 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0718 | 1 |
Onchocerca volvulus | 0.0456 | 0.5429 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0366 | 0.0674 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0294 | 0.0541 |
Echinococcus multilocularis | Protein lozenge | 0.0057 | 0.0616 | 0.0603 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0014 | 0.0099 | 0.0084 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0424 | 0.2018 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0306 | 0.6751 |
Brugia malayi | CHE-14 protein | 0.0044 | 0.0451 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0114 | 0.1301 | 0.2577 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.0424 | 0.0821 |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Loa Loa (eye worm) | tumor suppressor | 0.0331 | 0.3921 | 0.7223 |
Echinococcus multilocularis | caspase 3 | 0.0084 | 0.0934 | 0.092 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0515 | 0.0949 |
Trypanosoma cruzi | metacaspase, putative | 0.0031 | 0.0294 | 0.3803 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Echinococcus multilocularis | caspase 8 | 0.0031 | 0.0294 | 0.028 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0012 | 0.0065 | 0.0165 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0283 | 0.0521 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0264 | 0.0499 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0032 | 0.0306 | 0.6751 |
Trypanosoma brucei | Metacaspase-4 | 0.0031 | 0.0294 | 0.3803 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0492 | 0.0957 |
Onchocerca volvulus | Cathepsin F homolog | 0.0017 | 0.0134 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0065 | 0.1315 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0424 | 0.2018 |
Schistosoma mansoni | topbp1 | 0.0032 | 0.0306 | 0.0585 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0134 | 0.0566 |
Echinococcus multilocularis | nibrin | 0.0032 | 0.0306 | 0.0292 |
Trypanosoma brucei | metacaspase MCA3 | 0.0031 | 0.0294 | 0.3803 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0294 | 0.6462 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0134 | 0.052 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0385 | 0.5131 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0134 | 0.012 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0515 | 0.7157 |
Schistosoma mansoni | DNA ligase IV | 0.0032 | 0.0306 | 0.0585 |
Brugia malayi | Muscleblind-like protein | 0.0154 | 0.1782 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0105 | 0.0193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0009 | 0.0033 | 0.0593 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.068 | 0.1333 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0032 | 0.0306 | 0.399 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0099 | 0.0397 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0032 | 0.0306 | 0.0585 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0036 | 0.0067 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.068 | 0.1333 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0385 | 0.0709 |
Echinococcus multilocularis | expressed conserved protein | 0.0095 | 0.1075 | 0.1062 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.068 | 1 |
Leishmania major | metacaspase, putative | 0.0031 | 0.0294 | 0.3144 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0492 | 0.0957 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0032 | 0.0306 | 0.6751 |
Onchocerca volvulus | 0.0014 | 0.0099 | 0.0182 | |
Echinococcus multilocularis | cathepsin L | 0.0009 | 0.0033 | 0.0019 |
Trypanosoma brucei | metacaspase MCA2 | 0.0031 | 0.0294 | 0.3803 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0036 | 0.0022 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0342 | 0.4413 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Plasmodium vivax | sentrin-specific protease 2, putative | 0.0015 | 0.0105 | 0.2858 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Echinococcus granulosus | cysteine protease | 0.0009 | 0.0033 | 0.0037 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0012 | 0.0065 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1149 | 0.2116 |
Echinococcus granulosus | muscleblind protein | 0.0154 | 0.1782 | 0.3539 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0492 | 0.0957 |
Echinococcus multilocularis | sentrin specific protease 1 | 0.0015 | 0.0105 | 0.009 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0193 |
Onchocerca volvulus | 0.0015 | 0.0105 | 0.0193 | |
Brugia malayi | hypothetical protein | 0.0041 | 0.0424 | 0.0782 |
Loa Loa (eye worm) | oxidoreductase | 0.0014 | 0.0099 | 0.0182 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0134 | 0.052 |
Echinococcus multilocularis | protein patched | 0.0044 | 0.0451 | 0.0437 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0032 | 0.0306 | 0.141 |
Giardia lamblia | Replication factor C, subunit 1 | 0.0032 | 0.0306 | 1 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0032 | 0.0306 | 0.3572 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0134 | 0.012 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Echinococcus granulosus | expressed conserved protein | 0.0095 | 0.1075 | 0.2124 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0134 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0569 | 0.1048 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0337 | 0.5715 |
Echinococcus granulosus | cathepsin l1 | 0.0012 | 0.0065 | 0.0101 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0049 | 0.0515 | 0.2485 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0032 | 0.0306 | 0.6751 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0032 | 0.0306 | 0.499 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0099 | 0.0182 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0049 | 0.0515 | 0.6716 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0515 | 0.0949 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.017 | 0.1973 | 1 |
Brugia malayi | tumor suppressor. | 0.0331 | 0.3921 | 0.7223 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0385 | 0.5131 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0515 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0099 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0134 | 0.1472 |
Plasmodium vivax | metacaspase 1, putative | 0.0031 | 0.0294 | 0.8022 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0009 | 0.0033 | 0.0037 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0044 | 0.0451 | 0.0874 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0017 | 0.0134 | 0.3657 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0044 | 0.0451 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0105 | 0.0193 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0306 | 0.0565 |
Plasmodium vivax | sentrin-specific protease 1, putative | 0.0015 | 0.0105 | 0.2858 |
Echinococcus granulosus | caspase 3 | 0.0084 | 0.0934 | 0.1841 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0049 | 0.0515 | 0.7157 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0049 | 0.0515 | 1 |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Trypanosoma brucei | metacaspase | 0.0031 | 0.0294 | 0.3803 |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0134 | 0.0247 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0432 | 0.0836 |
Echinococcus multilocularis | muscleblind protein | 0.0154 | 0.1782 | 0.177 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0049 | 0.0515 | 0.7157 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0049 | 0.0515 | 0.7157 |
Loa Loa (eye worm) | runx1 | 0.0057 | 0.0616 | 0.1135 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0101 | 0.1149 | 0.1136 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0044 | 0.0451 | 0.0437 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0017 | 0.0134 | 0.3657 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.0602 | 0.8847 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Schistosoma mansoni | lozenge | 0.0057 | 0.0616 | 0.1205 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0264 | 0.0486 |
Plasmodium vivax | vivapain-1 | 0.0009 | 0.0033 | 0.0901 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0283 | 0.0521 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0432 | 0.0836 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.2274 | 0.4525 |
Leishmania major | cathepsin L-like protease | 0.0066 | 0.0718 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0101 | 0.1149 | 0.2272 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0134 | 0.0566 |
Plasmodium vivax | vivapain-2 | 0.0017 | 0.0134 | 0.3657 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.0366 | 0.481 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0032 | 0.0306 | 0.4505 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0014 | 0.0099 | 0.2699 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Plasmodium falciparum | metacaspase-like protein | 0.0031 | 0.0294 | 0.8022 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0049 | 0.0515 | 0.7157 |
Echinococcus granulosus | cathepsin L | 0.0009 | 0.0033 | 0.0037 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0032 | 0.0306 | 0.8373 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0014 | 0.0099 | 0.2699 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0515 | 0.0949 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0306 | 0.6751 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0031 | 0.0294 | 0.0541 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0099 | 0.096 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0009 | 0.0033 | 0.0037 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0031 | 0.0294 | 0.0559 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0492 | 0.0957 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0134 | 0.0247 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0134 | 0.012 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0099 | 0.096 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.0424 | 0.0821 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0294 | 0.6462 |
Trypanosoma cruzi | SUMO1/Ulp2, putative | 0.0015 | 0.0105 | 0.1045 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.0134 | 0.012 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0037 | 0.0366 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0032 | 0.0306 | 0.141 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0306 | 0.6751 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.0134 | 0.0247 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0385 | 0.0742 |
Echinococcus granulosus | geminin | 0.0195 | 0.2274 | 0.4525 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.0134 | 0.0566 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.0134 | 0.0239 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0099 | 0.096 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0032 | 0.0306 | 0.399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0294 | 0.6462 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0009 | 0.0033 | 0.0061 |
Chlamydia trachomatis | DNA ligase | 0.0032 | 0.0306 | 0.7722 |
Schistosoma mansoni | hypothetical protein | 0.0422 | 0.5007 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0099 | 0.0182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Echinococcus multilocularis | protein dispatched 1 | 0.005 | 0.0525 | 0.0511 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0032 | 0.0306 | 0.6751 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0031 | 0.0294 | 0.4317 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0044 | 0.0451 | 0.0874 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0014 | 0.0099 | 0.0397 |
Brugia malayi | Cell death protein 3 precursor | 0.0031 | 0.0294 | 0.0541 |
Echinococcus multilocularis | sentrin specific protease 8 | 0.0015 | 0.0105 | 0.009 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.0099 | 0.2075 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0014 | 0.0099 | 0.0182 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0114 | 0.1301 | 0.1289 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0009 | 0.0033 | 0.0037 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0031 | 0.0294 | 0.6462 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0366 | 0.0674 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0037 | 0.0366 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0342 | 0.4413 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0337 | 0.4325 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0099 | 0.0182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0037 | 0.0366 | 1 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0015 | 0.0105 | 0.0181 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0014 | 0.0099 | 0.0182 |
Echinococcus granulosus | caspase | 0.0114 | 0.1301 | 0.2577 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0515 | 0.7157 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0032 | 0.0306 | 0.4505 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0099 | 0.0397 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0432 | 0.0836 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0099 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0366 | 0.0674 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0134 | 0.0247 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0014 | 0.0099 | 0.096 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0385 | 0.5131 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.068 | 0.1333 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0049 | 0.0515 | 0.2485 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0342 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0065 | 0.012 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0369 |
Loa Loa (eye worm) | Ulp1 protease | 0.0015 | 0.0105 | 0.0193 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0015 | 0.0105 | 0.1538 |
Brugia malayi | cathepsin L-like precursor | 0.0012 | 0.0065 | 0.012 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0015 | 0.0105 | 0.0181 |
Toxoplasma gondii | cathepsin CPL | 0.0017 | 0.0134 | 0.1968 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0451 | 0.083 |
Toxoplasma gondii | propionate-CoA ligase | 0.0014 | 0.0099 | 0.1452 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0385 | 0.0371 |
Brugia malayi | Temporarily assigned gene name protein 44 | 0.0028 | 0.0264 | 0.0486 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0103 | 0.1168 | 0.231 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0014 | 0.0099 | 0.0397 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0014 | 0.0099 | 0.096 |
Trypanosoma brucei | metacaspase 5, putative | 0.0031 | 0.0294 | 0.3803 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.0134 | 0.0247 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Echinococcus granulosus | dnaJ subfamily B | 0.0422 | 0.5007 | 1 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0015 | 0.0105 | 0.1538 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0065 | 0.012 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0014 | 0.0099 | 0.0339 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0031 | 0.0294 | 0.3803 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.5429 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0099 | 0.0182 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.0424 | 0.041 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0014 | 0.0099 | 0.1452 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.0134 | 0.012 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0424 | 0.2018 |
Echinococcus multilocularis | geminin | 0.0195 | 0.2274 | 0.2263 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0014 | 0.0099 | 0.1452 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0101 | 0.1149 | 0.2116 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Onchocerca volvulus | Cathepsin L homolog | 0.0017 | 0.0134 | 0.0247 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.0134 | 0.012 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0032 | 0.0306 | 0.6751 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0366 | 0.0674 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Echinococcus granulosus | caspase 8 | 0.0031 | 0.0294 | 0.0559 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Onchocerca volvulus | 0.0017 | 0.0134 | 0.0247 | |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0369 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.0134 | 0.0247 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.068 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0065 | 0.012 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0032 | 0.0306 | 0.0565 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1782 | 0.3282 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0492 | 0.0478 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0492 | 0.0907 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0306 | 0.399 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0009 | 0.0033 | 0.0593 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1782 | 0.3282 |
Echinococcus granulosus | nibrin | 0.0032 | 0.0306 | 0.0585 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0385 | 0.5656 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0294 | 0.0541 |
Trichomonas vaginalis | Sentrin-specific protease, putative | 0.0015 | 0.0105 | 0.2205 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Echinococcus granulosus | sentrin specific protease 1 | 0.0015 | 0.0105 | 0.0181 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.0134 | 0.0247 |
Echinococcus multilocularis | expressed conserved protein | 0.0155 | 0.1794 | 0.1782 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0049 | 0.0515 | 0.7157 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.068 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0065 | 0.1315 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0385 | 0.0742 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0385 | 0.8513 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0014 | 0.0099 | 0.2075 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0014 | 0.0099 | 0.0397 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.068 | 0.9384 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0145 | 0.1674 | 0.3323 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0294 | 0.6462 |
Echinococcus granulosus | hypothetical protein | 0.0028 | 0.0264 | 0.0499 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0145 | 0.1674 | 0.1662 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.0134 | 0.0247 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0017 | 0.0134 | 0.2864 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0031 | 0.0294 | 0.0541 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0306 | 0.399 |
Echinococcus multilocularis | sentrin specific protease 7 | 0.017 | 0.1973 | 0.1961 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0366 | 0.0674 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.0549 | 0.7525 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.0099 | 0.0397 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0036 | 0.0044 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0385 | 0.1813 |
Brugia malayi | AMP-binding enzyme family protein | 0.0049 | 0.0515 | 0.0949 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0037 | 0.0366 | 0.4596 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0193 |
Brugia malayi | topoisomerase | 0.0032 | 0.0306 | 0.0565 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0014 | 0.0099 | 0.096 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0683 | 0.1338 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0015 | 0.0105 | 0.0181 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0134 | 0.0247 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0032 | 0.0306 | 0.0292 |
Schistosoma mansoni | topbp1 | 0.0032 | 0.0306 | 0.0585 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0283 | 0.0537 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0294 | 0.8022 |
Trypanosoma cruzi | metacaspase, putative | 0.0031 | 0.0294 | 0.3803 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0385 | 0.0709 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0065 | 0.012 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0015 | 0.0105 | 0.2205 |
Plasmodium vivax | vivapain-3 | 0.0009 | 0.0033 | 0.0901 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0099 | 0.0397 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0718 | 1 |
Onchocerca volvulus | 0.0012 | 0.0065 | 0.012 | |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0031 | 0.0294 | 0.4317 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.0134 | 0.0239 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0114 | 0.1301 | 0.2577 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.0385 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0385 | 0.8513 |
Echinococcus granulosus | caspase 2 | 0.0031 | 0.0294 | 0.0559 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0066 | 0.0718 | 1 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0015 | 0.0105 | 0.0193 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 19 nM | In vitro binding property against kappa opioid receptor | ChEMBL. | No reference |
Activity (binding) | = 1840 nM | In vitro binding property against mu opioid receptor | ChEMBL. | No reference |
ED50 (functional) | = 12 mg kg-1 | Antagonistic effect on mouse phenylquinone writhing (PQW ) test, subcutaneous administration | ChEMBL. | No reference |
ED50 (functional) | = 32 mg kg-1 | Antagonistic effect on mouse phenylquinone writhing (PQW ) test, peroral administration | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.