Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Oryctolagus cuniculus | Voltage-gated L-type calcium channel alpha-1C subunit | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | transcription factor BTF3, putative | 0.0041 | 0.0429 | 0.6181 |
Brugia malayi | hypothetical protein | 0.0031 | 0.0291 | 0.0906 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0139 | 0.0139 |
Schistosoma mansoni | ferritin light chain | 0.001 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0313 | 0.0977 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0097 | 0.1194 | 0.1194 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0139 | 0.0139 |
Schistosoma mansoni | nardilysin (M16 family) | 0.0026 | 0.0222 | 0.0222 |
Schistosoma mansoni | ferritin light chain | 0.001 | 0.0005 | 0.0005 |
Schistosoma mansoni | ferritin | 0.001 | 0.0005 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0097 | 0.1194 | 0.1194 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0023 | 0.0179 | 0.0179 |
Echinococcus granulosus | 5'partial|nardilysin | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | apoferritin-2 | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | heat shock protein | 0.0038 | 0.039 | 0.039 |
Onchocerca volvulus | Protein cycle homolog | 0.0022 | 0.0164 | 0.0227 |
Echinococcus granulosus | expressed protein | 0.001 | 0.0005 | 0.0005 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.0179 | 0.171 |
Echinococcus granulosus | insulin degrading enzyme | 0.0026 | 0.0222 | 0.0222 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.0643 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0841 | 0.0841 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0841 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0038 | 0.039 | 0.0705 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.0179 | 0.171 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0038 | 0.039 | 0.8863 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0164 | 0.0512 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0139 | 0.0139 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.054 | 0.7265 | 0.7265 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0023 | 0.0179 | 0.0391 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0139 | 0.0435 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0056 | 0.0643 | 0.1288 |
Loa Loa (eye worm) | calcium channel | 0.0093 | 0.1143 | 0.3563 |
Trypanosoma cruzi | peptidase, putative | 0.0026 | 0.0222 | 0.2476 |
Echinococcus granulosus | heat shock protein | 0.0038 | 0.039 | 0.039 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0139 | 0.1779 | 0.5545 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0093 | 0.1143 | 0.1143 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0164 | 0.0512 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0841 | 0.0841 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0012 | 0.0012 |
Brugia malayi | Pre-SET motif family protein | 0.0244 | 0.3208 | 1 |
Schistosoma mansoni | insulysin unit 3 (M16 family) | 0.0026 | 0.0222 | 0.0222 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0038 | 0.039 | 0.5477 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.1707 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0093 | 0.1143 | 0.1143 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0355 | 0.0355 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0056 | 0.0643 | 0.1288 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0355 | 0.0355 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0023 | 0.0179 | 0.0391 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0139 | 0.0435 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0097 | 0.1194 | 0.3722 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0541 | 0.0541 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0357 | 0.0357 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0041 | 0.0429 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0038 | 0.039 | 0.5478 |
Schistosoma mansoni | endoplasmin | 0.0038 | 0.039 | 0.039 |
Onchocerca volvulus | 0.0034 | 0.0329 | 0.0687 | |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0139 | 0.0435 |
Schistosoma mansoni | insulysin unit 3 (M16 family) | 0.0026 | 0.0222 | 0.0222 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0139 | 0.0139 |
Plasmodium falciparum | endoplasmin, putative | 0.0023 | 0.0189 | 0.0243 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0022 | 0.0177 | 0.1675 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0023 | 0.0179 | 0.0557 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0023 | 0.0179 | 0.0472 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0023 | 0.0179 | 0.0179 |
Treponema pallidum | heat shock protein 90 | 0.003 | 0.0284 | 0.0629 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.1707 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Giardia lamblia | Grp94/Hsp90 | 0.003 | 0.0284 | 0.4987 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0139 | 0.0139 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0036 | 0.0357 | 0.0357 |
Trichomonas vaginalis | set domain proteins, putative | 0.0277 | 0.3668 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0038 | 0.039 | 0.5477 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0139 | 0.0435 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0139 | 0.0435 |
Trichomonas vaginalis | heat shock protein, putative | 0.0023 | 0.0189 | 0.05 |
Echinococcus granulosus | dnaJ subfamily B | 0.0478 | 0.6411 | 0.6411 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0179 | 0.0557 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0012 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.026 | 0.081 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0139 | 0.0435 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.074 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Schistosoma mansoni | hypothetical protein | 0.0478 | 0.6411 | 0.6411 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0065 | 0.0758 | 0.8998 |
Echinococcus multilocularis | neuropeptide s receptor | 0.054 | 0.7265 | 0.7265 |
Leishmania major | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1194 | 0.3722 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0093 | 0.1143 | 0.1143 |
Schistosoma mansoni | insulysin (M16 family) | 0.0014 | 0.0065 | 0.0065 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.054 | 0.7265 | 0.7265 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1143 | 0.3563 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0016 | 0.0083 | 0.0003 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0357 | 0.0357 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0097 | 0.1194 | 0.1194 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0139 | 0.0435 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.001 | 0.0012 | 0.0012 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.1707 |
Echinococcus granulosus | neuropeptide s receptor | 0.054 | 0.7265 | 0.7265 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0093 | 0.1143 | 0.1143 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0093 | 0.1143 | 0.1143 |
Schistosoma mansoni | transcription factor btf3 | 0.0041 | 0.0429 | 0.0429 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0016 | 0.0083 | 0.0891 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0541 | 0.1688 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0139 | 0.0158 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0031 | 0.0291 | 0.0291 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0023 | 0.0179 | 0.0179 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.001 | 0.0012 | 0.0012 |
Trichomonas vaginalis | heat shock protein, putative | 0.0038 | 0.039 | 0.1049 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.026 | 0.3018 |
Toxoplasma gondii | toxolysin TLN4 | 0.0011 | 0.0026 | 0.0208 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0139 | 0.0139 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0541 | 0.1688 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0139 | 0.0139 |
Echinococcus multilocularis | transcription factor btf3 | 0.0041 | 0.0429 | 0.0429 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.001 | 0.0002 | 0.0002 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0041 | 0.0429 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0179 | 0.0557 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Leishmania major | phosphoglycan beta 1,3 galactosyltransferase 5 | 0.0026 | 0.0222 | 0.183 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0139 | 0.0139 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0041 | 0.0429 | 0.618 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0139 | 0.0139 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0023 | 0.0179 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0012 | 0.0028 | 0.0087 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0429 | 0.1156 |
Echinococcus granulosus | 3'partial|nardilysin | 0.0026 | 0.0222 | 0.0222 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0841 | 1 |
Toxoplasma gondii | NAC domain-containing protein | 0.0041 | 0.0429 | 0.505 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0139 | 0.0435 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0541 | 0.0541 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0097 | 0.1194 | 0.1194 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus granulosus | heat shock protein 90 | 0.0038 | 0.039 | 0.039 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0038 | 0.039 | 0.4577 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0139 | 0.0139 |
Schistosoma mansoni | ferritin | 0.001 | 0.0005 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Schistosoma mansoni | heat shock protein | 0.0038 | 0.039 | 0.039 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.003 | 0.0284 | 0.0629 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0541 | 0.0541 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0139 | 0.0435 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus granulosus | transcription factor btf3 | 0.0041 | 0.0429 | 0.0429 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0016 | 0.0083 | 0.0891 |
Brugia malayi | Helix-loop-helix DNA-binding domain containing protein | 0.0022 | 0.0164 | 0.0512 |
Leishmania major | DNA polymerase eta, putative | 0.0023 | 0.0179 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Schistosoma mansoni | voltage-gated cation channel | 0.0093 | 0.1143 | 0.1143 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0139 | 0.0435 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.0841 | 0.1887 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0643 | 0.2004 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0023 | 0.0179 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Schistosoma mansoni | hypothetical protein | 0.0097 | 0.1194 | 0.1194 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus granulosus | dna polymerase kappa | 0.0023 | 0.0179 | 0.0179 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0038 | 0.039 | 0.8863 |
Trypanosoma cruzi | peptidase, putative | 0.0026 | 0.0222 | 0.2476 |
Brugia malayi | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Schistosoma mansoni | nardilysin (M16 family) | 0.0026 | 0.0222 | 0.0222 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0841 | 0.1887 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0032 | 0.0313 | 0.3661 |
Trichomonas vaginalis | heat shock protein, putative | 0.003 | 0.0284 | 0.076 |
Onchocerca volvulus | 0.0277 | 0.3668 | 1 | |
Echinococcus multilocularis | dnaJ subfamily B | 0.0478 | 0.6411 | 0.6411 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0016 | 0.0083 | 0.0083 |
Echinococcus granulosus | nardilysin | 0.0026 | 0.0222 | 0.0222 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0139 | 0.0139 |
Trichomonas vaginalis | heat shock protein, putative | 0.003 | 0.0284 | 0.076 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0164 | 0.0512 |
Plasmodium vivax | nicotinate-nucleotide adenylyltransferase, putative | 0.0333 | 0.4433 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0038 | 0.039 | 1 |
Brugia malayi | Hsp90 protein | 0.0016 | 0.0083 | 0.0258 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0139 | 0.0139 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0038 | 0.039 | 0.4577 |
Brugia malayi | nuclear receptor RXR | 0.001 | 0.0012 | 0.0038 |
Trichomonas vaginalis | endoplasmin, putative | 0.0023 | 0.0189 | 0.05 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0139 | 0.0435 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0038 | 0.039 | 0.5477 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0031 | 0.0291 | 0.0906 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0012 | 0.003 | 0.003 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0643 | 0.7389 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0139 | 0.0435 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0093 | 0.1143 | 0.1143 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0.0429 | 1 |
Schistosoma mansoni | ferritin | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0012 | 0.0038 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.003 | 0.0284 | 0.3587 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0541 | 0.0541 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0139 | 0.0139 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0139 | 0.0139 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0093 | 0.1143 | 0.1143 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0139 | 0.0139 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Loa Loa (eye worm) | ICD-1 protein | 0.0041 | 0.0429 | 0.1337 |
Schistosoma mansoni | endoplasmin | 0.0038 | 0.039 | 0.039 |
Echinococcus multilocularis | ferritin | 0.001 | 0.0005 | 0.0005 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0025 | 0.0217 | 0.0217 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0022 | 0.0164 | 0.0512 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0038 | 0.039 | 0.5478 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0139 | 0.0435 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Schistosoma mansoni | apoferritin-2 | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0025 | 0.0217 | 0.0217 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.003 | 0.0284 | 0.3587 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0023 | 0.0179 | 0.0391 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0056 | 0.0643 | 0.1288 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0541 | 0.0541 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0179 | 0.0557 |
Brugia malayi | Pre-SET motif family protein | 0.0036 | 0.0357 | 0.1114 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Echinococcus multilocularis | insulin degrading enzyme | 0.0026 | 0.0222 | 0.0222 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.0643 | 1 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0139 | 0.0435 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0357 | 0.0357 |
Schistosoma mansoni | ferritin | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0164 | 0.0512 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0032 | 0.0313 | 0.4116 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0164 | 0.0512 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Loa Loa (eye worm) | endoplasmin | 0.0038 | 0.039 | 0.1215 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.001 | 0.0002 | 0.0002 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Echinococcus multilocularis | nardilysin | 0.0026 | 0.0222 | 0.0222 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0139 | 0.0139 |
Brugia malayi | MH2 domain containing protein | 0.0139 | 0.1779 | 0.5545 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Schistosoma mansoni | microtubule-associated protein tau | 0.074 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0369 | 0.115 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0093 | 0.1143 | 0.1143 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0056 | 0.0643 | 0.7622 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0139 | 0.0435 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0097 | 0.1194 | 0.1194 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.001 | 0.0012 | 0.0012 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | helix-loop-helix DNA-binding domain-containing protein | 0.0022 | 0.0164 | 0.0512 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0244 | 0.3208 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.003 | 0.0284 | 0.076 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0038 | 0.039 | 0.5477 |
Mycobacterium leprae | PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC | 0.0333 | 0.4433 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0023 | 0.0179 | 0.0179 |
Brugia malayi | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0038 | 0.039 | 0.5477 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0139 | 0.0139 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0093 | 0.1143 | 0.1143 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0139 | 0.1779 | 0.5545 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0023 | 0.0179 | 0.0179 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0291 | 0.0906 |
Toxoplasma gondii | rhoptry metalloprotease toxolysin TLN1 | 0.0026 | 0.0222 | 0.2557 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.003 | 0.0284 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0041 | 0.0429 | 0.618 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0023 | 0.0179 | 0.1707 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0139 | 0.0139 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0036 | 0.0357 | 0.0357 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0036 | 0.0357 | 0.0357 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0072 | 0.0862 | 0.0862 |
Trypanosoma brucei | peptidase, putative | 0.0026 | 0.0222 | 0.2478 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.001 | 0.0002 | 0.0002 |
Schistosoma mansoni | apoptosis regulator bax | 0.0097 | 0.1194 | 0.1194 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0139 | 0.0139 |
Mycobacterium ulcerans | heat shock protein 90 | 0.003 | 0.0284 | 0.0629 |
Echinococcus multilocularis | dna polymerase kappa | 0.0023 | 0.0179 | 0.0179 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0139 | 0.0139 |
Schistosoma mansoni | heat shock protein | 0.0016 | 0.0083 | 0.0083 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0023 | 0.0179 | 0.171 |
Loa Loa (eye worm) | insulin-degrading enzyme | 0.0026 | 0.0222 | 0.0691 |
Schistosoma mansoni | aryl hydrocarbon receptor nuclear translocator homolog (darnt) | 0.0022 | 0.0164 | 0.0164 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0002 | 0.0002 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0038 | 0.039 | 0.5478 |
Onchocerca volvulus | 0.0036 | 0.0357 | 0.0765 | |
Schistosoma mansoni | heat shock protein | 0.0038 | 0.039 | 0.039 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0139 | 0.0139 |
Toxoplasma gondii | sporozoite developmental protein | 0.0026 | 0.0222 | 0.2557 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0139 | 0.0158 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0355 | 0.0355 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0139 | 0.0158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0429 | 0.1156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0139 | 0.0139 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0841 | 0.0841 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0429 | 0.1156 |
Echinococcus multilocularis | nardilysin | 0.0016 | 0.0083 | 0.0083 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0329 | 0.0329 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.003 | 0.0284 | 0.0629 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0056 | 0.0643 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Trichomonas vaginalis | heat shock protein, putative | 0.0016 | 0.0083 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0016 | 0.0083 | 0.0083 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0031 | 0.0291 | 0.0291 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0032 | 0.0313 | 0.0313 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.003 | 0.0284 | 0.0284 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0139 | 0.0139 |
Brugia malayi | aryl hydrocarbon receptor nuclear translocator protein, putative | 0.0022 | 0.0164 | 0.0512 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0841 | 0.1887 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0023 | 0.0179 | 0.0472 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.001 | 0.0012 | 0.0038 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | histone methyltransferase | 0.0012 | 0.003 | 0.0092 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus granulosus | heat shock protein 90 | 0.003 | 0.0284 | 0.0284 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0841 | 0.1887 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0139 | 0.0435 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0139 | 0.0435 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.171 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.003 | 0.0284 | 0.4987 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0032 | 0.0313 | 0.0977 |
Mycobacterium ulcerans | bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein | 0.0333 | 0.4433 | 1 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0097 | 0.1194 | 0.1194 |
Schistosoma mansoni | family M16 unassigned peptidase (M16 family) | 0.001 | 0.0009 | 0.0009 |
Mycobacterium tuberculosis | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic | 0.0333 | 0.4433 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0139 | 0.0139 |
Leishmania major | basic transcription factor 3a, putative | 0.0041 | 0.0429 | 0.4566 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0139 | 0.0435 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0041 | 0.0429 | 0.0796 |
Schistosoma mansoni | hypothetical protein | 0.0097 | 0.1194 | 0.1194 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0012 | 0.0038 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0355 | 0.0355 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0093 | 0.1143 | 0.1143 |
Echinococcus multilocularis | endoplasmin | 0.003 | 0.0284 | 0.0284 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0032 | 0.0313 | 0.4118 |
Onchocerca volvulus | 0.002 | 0.0139 | 0.0158 | |
Plasmodium falciparum | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 0.0333 | 0.4433 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0139 | 0.0435 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0139 | 0.0435 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0164 | 0.0512 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0016 | 0.0083 | 0.0258 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0036 | 0.0357 | 0.4188 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0139 | 0.0435 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0093 | 0.1143 | 0.3563 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus multilocularis | expressed protein | 0.001 | 0.0005 | 0.0005 |
Echinococcus granulosus | dna polymerase eta | 0.0023 | 0.0179 | 0.0179 |
Treponema pallidum | hypothetical protein | 0.0333 | 0.4433 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0036 | 0.0357 | 0.0357 |
Trypanosoma brucei | unspecified product | 0.0023 | 0.0179 | 0.171 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Onchocerca volvulus | 0.0031 | 0.0291 | 0.058 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0139 | 0.0435 |
Plasmodium vivax | SET domain protein, putative | 0.0036 | 0.0357 | 0.0631 |
Brugia malayi | Endoplasmin precursor | 0.0038 | 0.039 | 0.1215 |
Toxoplasma gondii | peptidase M16 inactive domain-containing protein | 0.0016 | 0.0083 | 0.0889 |
Echinococcus granulosus | endoplasmin | 0.003 | 0.0284 | 0.0284 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0541 | 0.0541 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0093 | 0.1143 | 0.1143 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.003 | 0.0284 | 0.2651 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.026 | 0.081 |
Chlamydia trachomatis | insulinase family protease III | 0.0026 | 0.0222 | 1 |
Echinococcus multilocularis | nardilysin | 0.0026 | 0.0222 | 0.0222 |
Brugia malayi | beta-NAC-like protein | 0.0041 | 0.0429 | 0.1337 |
Echinococcus multilocularis | heat shock protein 90 | 0.0038 | 0.039 | 0.039 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0038 | 0.039 | 0.1215 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0139 | 0.0435 |
Toxoplasma gondii | insulysin, putative | 0.0024 | 0.0204 | 0.235 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus multilocularis | dna polymerase eta | 0.0023 | 0.0179 | 0.0179 |
Trypanosoma brucei | heat shock protein, putative | 0.0038 | 0.039 | 0.5478 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0139 | 0.0139 |
Plasmodium vivax | endoplasmin, putative | 0.0038 | 0.039 | 0.0705 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0012 | 0.0038 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.0329 | 0.1026 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0139 | 0.0139 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0097 | 0.1194 | 0.3722 |
Echinococcus multilocularis | heat shock protein 90 | 0.003 | 0.0284 | 0.0284 |
Leishmania major | heat shock protein 83-1 | 0.0038 | 0.039 | 0.4047 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0093 | 0.1143 | 0.1143 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.0179 | 0.171 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.0329 | 0.1026 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0139 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0643 | 0.2004 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0841 | 0.0841 |
Brugia malayi | insulin-degrading enzyme | 0.0026 | 0.0222 | 0.0691 |
Plasmodium vivax | heat shock protein 86, putative | 0.0038 | 0.039 | 0.0705 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0541 | 0.0541 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0023 | 0.0179 | 0.1707 |
Echinococcus granulosus | ferritin | 0.001 | 0.0005 | 0.0005 |
Brugia malayi | heat shock protein 90 | 0.0038 | 0.039 | 0.1215 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0023 | 0.0179 | 0.1262 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0357 | 0.1114 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.033 | 0.033 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0139 | 0.0139 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0139 | 0.0139 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.