Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Mycobacterium ulcerans | oxygenase | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Hypothetical oxidoreductase | 0.0023 | 0.0463 | 0.0283 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0141 | 0.4872 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0141 | 0.4872 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0019 | 0.0334 | 0.0259 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0925 | 0.0877 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.2465 | 0.3166 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0019 | 0.0334 | 0.0259 |
Leishmania major | trypanothione reductase | 0.0056 | 0.1689 | 0.222 |
Loa Loa (eye worm) | glutathione reductase | 0.0056 | 0.1689 | 0.1729 |
Brugia malayi | RNA binding protein | 0.0052 | 0.1564 | 0.1475 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | flavodoxin family protein | 0.0077 | 0.2465 | 0.2411 |
Echinococcus granulosus | methionine synthase reductase | 0.0124 | 0.4215 | 0.5767 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0127 | 0.4344 | 0.8837 |
Onchocerca volvulus | 0.0035 | 0.0925 | 0.0484 | |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0099 | 0.3311 | 1 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.02 | 0.7063 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0056 | 0.1689 | 0.1729 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0876 | 0.0806 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.02 | 0.7063 | 1 |
Brugia malayi | Flap endonuclease-1 | 0.0031 | 0.0758 | 0.0638 |
Trypanosoma brucei | nitrate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.02 | 0.7063 | 1 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.02 | 0.7063 | 1 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | oxidoreductase-protein, putative | 0.0023 | 0.0463 | 0.0445 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0077 | 0.2465 | 0.3166 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0012 |
Trypanosoma cruzi | nitrate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0925 | 0.0877 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0056 | 0.1689 | 0.2985 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0031 | 0.0758 | 0.0629 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0056 | 0.1689 | 0.2013 |
Plasmodium vivax | ferredoxin--NADP reductase, putative | 0.0023 | 0.0463 | 0.0191 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0012 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0925 | 0.0877 |
Mycobacterium tuberculosis | Possible oxygenase | 0.0023 | 0.0463 | 0.0283 |
Trypanosoma brucei | NADH-cytochrome b5 reductase-like protein | 0.0023 | 0.0463 | 0.0445 |
Schistosoma mansoni | cytochrome P450 reductase | 0.02 | 0.7063 | 1 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0031 | 0.0758 | 0.0775 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | FAD binding domain containing protein | 0.0124 | 0.4215 | 0.4229 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.02 | 0.7063 | 1 |
Brugia malayi | glutathione reductase | 0.0056 | 0.1689 | 0.1605 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium vivax | oxidoreductase NAD-binding domain containing protein | 0.0023 | 0.0463 | 0.0191 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | TAR-binding protein | 0.0052 | 0.1564 | 0.1475 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.02 | 0.7063 | 1 |
Toxoplasma gondii | ferredoxin NADP+ oxidoreductase FNR | 0.0023 | 0.0463 | 0.0431 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Mycobacterium ulcerans | oxidoreductase | 0.0023 | 0.0463 | 0.0445 |
Leishmania major | cytochrome P450 reductase, putative | 0.0178 | 0.6217 | 0.8774 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | FAD binding domain containing protein | 0.02 | 0.7063 | 0.7189 |
Toxoplasma gondii | thioredoxin reductase | 0.0056 | 0.1689 | 0.455 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0925 | 0.0811 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Brugia malayi | flavodoxin family protein | 0.02 | 0.7063 | 0.7189 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0159 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Probable reductase | 0.0127 | 0.4344 | 0.8837 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0077 | 0.2465 | 0.3166 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0925 | 0.0946 |
Mycobacterium ulcerans | flavodoxin oxidoreductase | 0.0023 | 0.0463 | 0.0445 |
Leishmania major | oxidoreductase-like protein | 0.0023 | 0.0463 | 0.0445 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0925 | 0.1983 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Leishmania major | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0101 | 0.3368 | 0.4508 |
Plasmodium falciparum | thioredoxin reductase | 0.0056 | 0.1689 | 0.2013 |
Echinococcus multilocularis | methionine synthase reductase | 0.0124 | 0.4215 | 0.5767 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0077 | 0.2465 | 0.3343 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | Pre-SET motif family protein | 0.0245 | 0.874 | 0.893 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0052 | 0.1564 | 0.1475 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.02 | 0.7063 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0159 |
Loa Loa (eye worm) | TAR-binding protein | 0.0052 | 0.1564 | 0.1601 |
Leishmania major | NADH-dependent fumarate reductase-like protein | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Mycobacterium ulcerans | flavodoxin reductase Hmp | 0.0023 | 0.0463 | 0.0445 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0141 | 0.4872 | 1 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0031 | 0.0758 | 0.0629 |
Trypanosoma cruzi | p450 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trichomonas vaginalis | sulfite reductase, putative | 0.02 | 0.7063 | 0.6962 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium falciparum | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0191 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0925 | 0.0877 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0077 | 0.2465 | 0.3343 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0178 | 0.6217 | 1 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0077 | 0.2465 | 0.3343 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.02 | 0.7063 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0178 | 0.6217 | 0.6086 |
Toxoplasma gondii | NADH-cytochrome b5 reductase 1, putative | 0.0023 | 0.0463 | 0.0431 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Plasmodium falciparum | ferredoxin--NADP reductase | 0.0023 | 0.0463 | 0.0191 |
Echinococcus granulosus | flap endonuclease 1 | 0.0031 | 0.0758 | 0.0629 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0925 | 0.0877 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0127 | 0.4344 | 0.8837 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0077 | 0.2465 | 0.2523 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0334 | 0.5 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0031 | 0.0758 | 0.0872 |
Leishmania major | nitrate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Leishmania major | p450 reductase, putative | 0.02 | 0.7063 | 1 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0099 | 0.3311 | 0.4424 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0052 | 0.1564 | 0.1601 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0191 |
Trypanosoma cruzi | oxidoreductase-protein, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Probable monooxygenase | 0.0023 | 0.0463 | 0.0283 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Loa Loa (eye worm) | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0473 |
Loa Loa (eye worm) | diaphorase | 0.0023 | 0.0463 | 0.0473 |
Echinococcus multilocularis | tar DNA binding protein | 0.0052 | 0.1564 | 0.1827 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0077 | 0.2465 | 0.3343 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Chlamydia trachomatis | sulfite reductase | 0.0124 | 0.4215 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0334 | 0.0259 |
Treponema pallidum | flavodoxin | 0.0077 | 0.2465 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0056 | 0.1689 | 0.1605 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0925 | 0.0877 |
Giardia lamblia | Flavohemoprotein lateral transfer candidate | 0.0023 | 0.0463 | 0.0218 |
Schistosoma mansoni | NADH-cytochrome B5 reductase | 0.0023 | 0.0463 | 0.0191 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0127 | 0.4344 | 0.8837 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0127 | 0.4344 | 0.8837 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0099 | 0.3311 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.7063 | 0.723 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.2465 | 0.3343 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0031 | 0.0758 | 0.0872 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Brugia malayi | diaphorase | 0.0023 | 0.0463 | 0.0331 |
Giardia lamblia | Hypothetical protein | 0.0178 | 0.6217 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0031 | 0.0758 | 0.072 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0031 | 0.0758 | 0.0438 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0178 | 0.6217 | 0.8742 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0056 | 0.1689 | 0.2013 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0056 | 0.1689 | 0.2013 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | trypanothione reductase | 0.0056 | 0.1689 | 0.222 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0925 | 0.0877 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0141 | 0.4872 | 1 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.02 | 0.7063 | 0.723 |
Chlamydia trachomatis | Na(+)-translocating NADH-quinone reductase subunit F | 0.0023 | 0.0463 | 0.0331 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0023 | 0.0463 | 0.0445 |
Echinococcus granulosus | NADH cytochrome b5 reductase 3 | 0.0023 | 0.0463 | 0.0191 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Schistosoma mansoni | flap endonuclease-1 | 0.0028 | 0.0648 | 0.0466 |
Loa Loa (eye worm) | RNA binding protein | 0.0052 | 0.1564 | 0.1601 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0124 | 0.4215 | 0.5767 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0031 | 0.0758 | 0.0872 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0023 | 0.0463 | 0.0283 |
Echinococcus multilocularis | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0191 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0056 | 0.1689 | 0.222 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Schistosoma mansoni | cytochrome B5 | 0.0023 | 0.0463 | 0.0191 |
Mycobacterium ulcerans | electron transfer protein FdxB | 0.0023 | 0.0463 | 0.0445 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0245 | 0.874 | 0.8946 |
Brugia malayi | follicle stimulating hormone receptor | 0.0273 | 0.9769 | 1 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0925 | 0.0877 |
Trypanosoma cruzi | p450 reductase, putative | 0.02 | 0.7063 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0023 | 0.0463 | 0.0283 |
Trypanosoma cruzi | reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0127 | 0.4344 | 0.8837 |
Treponema pallidum | ferredoxin-NADP(+) reductase subunit alpha | 0.0023 | 0.0463 | 0.0602 |
Echinococcus multilocularis | NADH cytochrome b5 reductase 3 | 0.0023 | 0.0463 | 0.0191 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0124 | 0.4215 | 0.4314 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.02 | 0.7063 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0052 | 0.1564 | 0.1827 |
Leishmania major | reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium falciparum | flap endonuclease 1 | 0.0031 | 0.0758 | 0.0629 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0031 | 0.0758 | 0.1422 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0334 | 0.0198 |
Brugia malayi | Cytochrome b5-like Heme/Steroid binding domain containing protein | 0.0023 | 0.0463 | 0.0331 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.02 | 0.7063 | 1 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.02 | 0.7063 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0273 | 0.9769 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0334 | 0.0259 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0334 | 0.5 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0015 | 0.0155 | 0.0159 |
Plasmodium falciparum | glutathione reductase | 0.0056 | 0.1689 | 0.2013 |
Trichomonas vaginalis | set domain proteins, putative | 0.0279 | 1 | 1 |
Mycobacterium ulcerans | monooxygenase | 0.0023 | 0.0463 | 0.0445 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0191 |
Plasmodium vivax | glutathione reductase, putative | 0.0056 | 0.1689 | 0.2013 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | < 10 mg kg-1 | Ability to cause 50% reduction in sorbitol levels of sciatic nerve of streptozotocinized rats was determined | ChEMBL. | 3121857 |
IC50 (binding) | > 0.0001 M | In vitro inhibitory activity of the compound towards partially purified human placenta aldose reductase | ChEMBL. | 3121857 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.