Detailed information for compound 1484963

Basic information

Technical information
  • TDR Targets ID: 1484963
  • Name: 4-bromo-N-[2-(2,3-dihydro-1H-inden-5-ylamino) -2-oxoethyl]benzamide
  • MW: 373.244 | Formula: C18H17BrN2O2
  • H donors: 2 H acceptors: 2 LogP: 3.63 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc2c(c1)CCC2)CNC(=O)c1ccc(cc1)Br
  • InChi: 1S/C18H17BrN2O2/c19-15-7-4-13(5-8-15)18(23)20-11-17(22)21-16-9-6-12-2-1-3-14(12)10-16/h4-10H,1-3,11H2,(H,20,23)(H,21,22)
  • InChiKey: FSIZJEIFEFTXJC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-bromo-N-[2-(indan-5-ylamino)-2-oxo-ethyl]benzamide
  • 4-bromo-N-[2-(5-indanylamino)-2-oxoethyl]benzamide
  • 4-bromo-N-[2-(indan-5-ylamino)-2-keto-ethyl]benzamide
  • 4-bromo-N-[2-(2,3-dihydro-1H-inden-5-ylamino)-2-oxo-ethyl]benzamide
  • T5350396
  • ZINC05938112

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0122 0.011 0.011
Giardia lamblia Cathepsin L precursor 0.0122 0.011 0.1049
Leishmania major cathepsin L-like protease 0.0653 0.1178 1
Trypanosoma brucei calpain, putative 0.0102 0.007 0.0596
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Trypanosoma brucei Calpain-like protein CALP1.3 0.0102 0.007 0.0596
Loa Loa (eye worm) calpain 0.0377 0.0624 0.2013
Brugia malayi cathepsin Z-like cysteine proteinase 0.0122 0.011 0.0356
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0122 0.011 0.1406
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1608 0.3098 0.3098
Schistosoma mansoni cathepsin B (C01 family) 0.0122 0.011 0.011
Echinococcus granulosus cathepsin L 0.0122 0.011 0.0356
Trichomonas vaginalis calpain, putative 0.0102 0.007 0.0679
Brugia malayi cathepsin Z-like cysteine proteinase 0.0122 0.011 0.0356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.011 0.1065
Plasmodium falciparum serine repeat antigen 8 0.0122 0.011 0.1406
Giardia lamblia Cathepsin L precursor 0.0122 0.011 0.1049
Loa Loa (eye worm) hypothetical protein 0.065 0.1171 0.3782
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0122 0.011 0.0356
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0122 0.011 0.1406
Echinococcus granulosus calcium uptake protein 1 0.0068 0.0002 0.0006
Trypanosoma brucei caltractin, putative 0.0086 0.0039 0.0328
Entamoeba histolytica cysteine proteinase, putative 0.0258 0.0383 0.489
Trichomonas vaginalis calpain, putative 0.0102 0.007 0.0679
Onchocerca volvulus 0.0457 0.0783 0.6687
Trypanosoma brucei hypothetical protein 0.0102 0.007 0.0596
Brugia malayi Cathepsin L-like precursor 0.0457 0.0783 0.2529
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0258 0.0383 0.1237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.011 0.1065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.007 0.0227
Onchocerca volvulus Cathepsin L homolog 0.0457 0.0783 0.6687
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0122 0.011 0.1406
Plasmodium vivax calpain, putative 0.0377 0.0624 0.7959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Leishmania major calpain protease-like protein 0.0102 0.007 0.0596
Trypanosoma cruzi cysteine proteinase, putative 0.0258 0.0383 0.1237
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0108 1
Giardia lamblia Hypothetical protein 0.0122 0.011 0.1049
Plasmodium falciparum plasmepsin IV 0.0096 0.0059 0.0756
Giardia lamblia Cysteine protease 0.0122 0.011 0.1049
Trypanosoma cruzi kinesin, putative 0.0275 0.0419 0.1352
Giardia lamblia Cathepsin L precursor 0.0122 0.011 0.1049
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0122 0.011 0.1406
Trichomonas vaginalis calmodulin, putative 0.0068 0.0002 0.0018
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Trypanosoma cruzi conserved protein 0.0102 0.007 0.0227
Onchocerca volvulus 0.0321 0.051 0.4357
Trichomonas vaginalis hypothetical protein 0.0102 0.007 0.0679
Brugia malayi EF hand family protein 0.0068 0.0002 0.0006
Schistosoma mansoni cathepsin D (A01 family) 0.0284 0.0437 0.0437
Echinococcus granulosus cathepsin L 0.0258 0.0383 0.1237
Giardia lamblia Hypothetical protein 0.0122 0.011 0.1049
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0122 0.011 0.1065
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0377 0.0624 0.2013
Trypanosoma brucei calpain-like protein, putative 0.0377 0.0624 0.5291
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0122 0.011 0.011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0377 0.0624 0.2013
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0457 0.0783 0.2529
Echinococcus multilocularis hypothetical protein 0.0377 0.0624 0.2013
Echinococcus multilocularis calpain A 0.1095 0.2066 0.6669
Plasmodium falciparum serine repeat antigen 4 0.0122 0.011 0.1406
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Echinococcus multilocularis cathepsin L cysteine protease 0.0457 0.0783 0.2529
Loa Loa (eye worm) fibroinase 0.0457 0.0783 0.2529
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0096 0.0059 0.0573
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0102 0.007 0.0679
Echinococcus multilocularis calumenin 0.0068 0.0002 0.0006
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0102 0.007 0.0227
Plasmodium falciparum plasmepsin II 0.0096 0.0059 0.0756
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Brugia malayi Cathepsin L-like precursor 0.0321 0.051 0.1648
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0122 0.011 0.1406
Trypanosoma cruzi centrin, putative 0.0086 0.0039 0.0125
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0122 0.011 0.011
Plasmodium falciparum serine repeat antigen 2 0.0122 0.011 0.1406
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0122 0.011 0.1406
Loa Loa (eye worm) hypothetical protein 0.0925 0.1725 0.5568
Trypanosoma brucei Calpain-like protein 1.1 0.0102 0.007 0.0596
Giardia lamblia Cathepsin B precursor 0.0122 0.011 0.1049
Trypanosoma brucei cysteine peptidase, putative 0.0102 0.007 0.0596
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0377 0.0624 0.2013
Echinococcus multilocularis cathepsin L 0.0122 0.011 0.0356
Entamoeba histolytica hypothetical protein 0.0122 0.011 0.1406
Entamoeba histolytica cysteine proteinase, putative 0.0258 0.0383 0.489
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0102 0.007 0.0679
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0102 0.007 0.0679
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Loa Loa (eye worm) hypothetical protein 0.1608 0.3098 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Loa Loa (eye worm) hypothetical protein 0.0136 0.0138 0.0447
Echinococcus multilocularis calpain family protein 1, d 0.0752 0.1376 0.4443
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.011 0.1065
Loa Loa (eye worm) cysteine protease 0.0457 0.0783 0.2529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0581 0.1034 0.1034
Onchocerca volvulus 0.0457 0.0783 0.6687
Plasmodium vivax vivapain-2 0.0457 0.0783 1
Leishmania major hypothetical protein, conserved 0.0102 0.007 0.0596
Schistosoma mansoni cathepsin S (C01 family) 0.0122 0.011 0.011
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0122 0.011 0.1406
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0122 0.011 0.011
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Plasmodium vivax unspecified product 0.0258 0.0383 0.489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Schistosoma mansoni calpain-7 (C02 family) 0.0377 0.0624 0.0624
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.2013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0122 0.011 0.1049
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.5291
Trypanosoma cruzi kinesin, putative 0.0275 0.0419 0.1352
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0917 0.1708 0.1708
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0102 0.007 0.0679
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1094 0.2064 0.2064
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0122 0.011 0.1406
Leishmania major cathepsin L-like protease 0.0457 0.0783 0.6648
Entamoeba histolytica cysteine proteinase 1, putative 0.0258 0.0383 0.489
Plasmodium vivax aspartyl proteinase, putative 0.0096 0.0059 0.0756
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Schistosoma mansoni cathepsin F (C01 family) 0.0457 0.0783 0.0783
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Loa Loa (eye worm) calpain family protein 1 0.0752 0.1376 0.4443
Giardia lamblia Cathepsin B precursor 0.0122 0.011 0.1049
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0122 0.011 0.1049
Onchocerca volvulus 0.0457 0.0783 0.6687
Brugia malayi Cathepsin L-like precursor 0.0321 0.051 0.1648
Leishmania major cysteine peptidase A (CPA) 0.0457 0.0783 0.6648
Loa Loa (eye worm) calpain D 0.0102 0.007 0.0227
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1027 0.193 0.193
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0096 0.0059 0.0573
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0122 0.011 0.011
Plasmodium falciparum calpain 0.0102 0.007 0.0897
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0102 0.007 0.0679
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0122 0.011 0.0356
Echinococcus multilocularis calpain 7 (C02 family) 0.0377 0.0624 0.2013
Brugia malayi cathepsin B-like cysteine proteinase 0.1608 0.3098 1
Schistosoma mansoni hypothetical protein 0.0102 0.007 0.007
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0122 0.011 0.1406
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1608 0.3098 0.3098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0377 0.0624 0.2013
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0122 0.011 0.011
Leishmania major cathepsin L-like protease 0.0457 0.0783 0.6648
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0122 0.011 0.1406
Brugia malayi Papain family cysteine protease containing protein 0.0457 0.0783 0.2529
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0122 0.011 0.1065
Brugia malayi cathepsin F-like cysteine proteinase 0.0122 0.011 0.0356
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0068 0.0002 0.0002
Onchocerca volvulus 0.065 0.1171 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0321 0.051 0.4936
Entamoeba histolytica cysteine proteinase, putative 0.0457 0.0783 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.0059 0.0191
Trypanosoma cruzi major cysteine proteinase, putative 0.0318 0.0505 0.1631
Entamoeba histolytica grainin, putative 0.0068 0.0002 0.0024
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0377 0.0624 0.2013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Trypanosoma brucei calpain-like protein, putative 0.0377 0.0624 0.5291
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0122 0.011 0.0356
Entamoeba histolytica cysteine protease, putative 0.0122 0.011 0.1406
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0122 0.011 0.1406
Schistosoma mansoni calpain C (C02 family) 0.0377 0.0624 0.0624
Trypanosoma cruzi centrin, putative 0.0086 0.0039 0.0125
Trypanosoma brucei calmodulin, putative 0.0068 0.0002 0.0016
Onchocerca volvulus Cathepsin L homolog 0.0457 0.0783 0.6687
Loa Loa (eye worm) hypothetical protein 0.0122 0.011 0.0356
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0102 0.007 0.0596
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0096 0.0059 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.011 0.1065
Brugia malayi Papain family cysteine protease containing protein 0.0122 0.011 0.0356
Trypanosoma cruzi cruzipain precursor, putative 0.0653 0.1178 0.3804
Trypanosoma cruzi cruzipain precursor, putative 0.0136 0.0138 0.0447
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Entamoeba histolytica cysteine protease, putative 0.0122 0.011 0.1406
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Giardia lamblia Cysteine protease 0.0122 0.011 0.1049
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0102 0.007 0.0596
Brugia malayi Cathepsin L-like precursor 0.0136 0.0138 0.0447
Echinococcus multilocularis programmed cell death protein 0.0086 0.0039 0.0125
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0122 0.011 0.011
Plasmodium vivax serine-repeat antigen (SERA) 0.0122 0.011 0.1406
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0258 0.0383 0.0383
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0002 0.0024
Loa Loa (eye worm) programmed cell death protein 6 0.0068 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0752 0.1376 0.4443
Leishmania major cathepsin L-like protease 0.0457 0.0783 0.6648
Toxoplasma gondii calmodulin CAM1 0.0068 0.0002 0.0018
Leishmania major hypothetical protein, conserved 0.0068 0.0002 0.0016
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0102 0.007 0.0679
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.007 0.0227
Entamoeba histolytica cysteine protease, putative 0.0122 0.011 0.1406
Plasmodium falciparum serine repeat antigen 1 0.0122 0.011 0.1406
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Brugia malayi Papain family cysteine protease containing protein 0.0258 0.0383 0.1237
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0096 0.0059 0.0191
Onchocerca volvulus Cathepsin F homolog 0.0457 0.0783 0.6687
Echinococcus granulosus calpain 5 0.0377 0.0624 0.2013
Plasmodium vivax unspecified product 0.0122 0.011 0.1406
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0457 0.0783 0.7575
Onchocerca volvulus Cathepsin L homolog 0.0122 0.011 0.0941
Plasmodium falciparum serine repeat antigen 3 0.0122 0.011 0.1406
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Echinococcus granulosus calpain 0.0377 0.0624 0.2013
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0108 1
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0068 0.0002 0.0006
Entamoeba histolytica protein kinase, putative 0.0275 0.0419 0.5345
Brugia malayi calpain 5 0.0275 0.0419 0.1352
Trichomonas vaginalis calmodulin, putative 0.0086 0.0039 0.0373
Onchocerca volvulus 0.0457 0.0783 0.6687
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0122 0.011 0.1406
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Loa Loa (eye worm) calpain family protein 1 0.1027 0.193 0.6229
Entamoeba histolytica calpain large subunit domain III containing protein 0.0275 0.0419 0.5345
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0581 0.1034 0.8777
Loa Loa (eye worm) hypothetical protein 0.0321 0.051 0.1648
Giardia lamblia Cathepsin B precursor 0.0122 0.011 0.1049
Plasmodium vivax vivapain-1 0.0258 0.0383 0.489
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0581 0.1034 1
Toxoplasma gondii aspartyl protease ASP1 0.0096 0.0059 0.0573
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Plasmodium falciparum serine repeat antigen 6 0.0122 0.011 0.1406
Brugia malayi fibroinase precursor 0.0122 0.011 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0122 0.011 0.1065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.007 0.0227
Trypanosoma cruzi cysteine peptidase, putative 0.0653 0.1178 0.3804
Echinococcus granulosus EF hand domain containing family member A2 0.0068 0.0002 0.0006
Brugia malayi Cathepsin L-like precursor 0.0457 0.0783 0.2529
Entamoeba histolytica cysteine proteinase, putative 0.0457 0.0783 1
Leishmania major cathepsin L-like protease 0.0457 0.0783 0.6648
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.2013
Echinococcus granulosus cathepsin l1 0.0321 0.051 0.1648
Echinococcus granulosus cathepsin b 0.1608 0.3098 1
Echinococcus multilocularis cathepsin L 0.0258 0.0383 0.1237
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0258 0.0383 0.0383
Loa Loa (eye worm) hypothetical protein 0.0457 0.0783 0.2529
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.011 0.1065
Brugia malayi cathepsin L precursor 0.0122 0.011 0.0356
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0136 0.0138 0.0447
Schistosoma mansoni calpain (C02 family) 0.0377 0.0624 0.0624
Echinococcus granulosus cathepsin L cysteine proteinase 0.0457 0.0783 0.2529
Loa Loa (eye worm) hypothetical protein 0.0102 0.007 0.0227
Brugia malayi calpain family protein 1 0.1027 0.193 0.6229
Plasmodium falciparum serine repeat antigen 9 0.0122 0.011 0.1406
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0517 0.0905 0.2923
Trypanosoma cruzi cysteine peptidase, putative 0.0258 0.0383 0.1237
Loa Loa (eye worm) hypothetical protein 0.0321 0.051 0.1648
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1608 0.3098 0.3098
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Leishmania major kinesin, putative 0.0275 0.0419 0.3553
Trypanosoma brucei calpain-like protein, putative 0.0377 0.0624 0.5291
Brugia malayi cathepsin L-like cysteine proteinase 0.0122 0.011 0.0356
Plasmodium vivax unspecified product 0.0136 0.0138 0.1766
Trypanosoma cruzi major cysteine proteinase, putative 0.0122 0.011 0.0356
Echinococcus granulosus tumor protein p63 0.0408 0.0686 0.2213
Echinococcus multilocularis cathepsin b 0.1608 0.3098 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Giardia lamblia Encystation-specific protease 0.0122 0.011 0.1049
Echinococcus granulosus calpain 7 C02 family 0.0377 0.0624 0.2013
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0122 0.011 0.0356
Giardia lamblia Cysteine protease 0.0122 0.011 0.1049
Plasmodium vivax vivapain-2 0.0457 0.0783 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0138 0.0447
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Trypanosoma brucei calpain-like protein, putative 0.0377 0.0624 0.5291
Plasmodium falciparum plasmepsin I 0.0096 0.0059 0.0756
Giardia lamblia Cathepsin B precursor 0.0581 0.1034 1
Plasmodium vivax vivapain-3 0.0258 0.0383 0.489
Loa Loa (eye worm) hypothetical protein 0.0122 0.011 0.0356
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0108 1
Brugia malayi calpain 7 0.0377 0.0624 0.2013
Echinococcus granulosus cathepsin l1 0.0457 0.0783 0.2529
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.011 0.1065
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.1094 0.2064 0.6663
Trypanosoma cruzi cysteine proteinase, putative 0.0258 0.0383 0.1237
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Brugia malayi calpain 5 0.0102 0.007 0.0227
Schistosoma mansoni cathepsin D (A01 family) 0.0284 0.0437 0.0437
Brugia malayi Papain family cysteine protease containing protein 0.0122 0.011 0.0356
Loa Loa (eye worm) cathepsin B 0.0581 0.1034 0.3338
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0122 0.011 0.1065
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1608 0.3098 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0122 0.011 0.1065
Echinococcus granulosus programmed cell death protein 0.0086 0.0039 0.0125
Echinococcus multilocularis cysteine protease 0.0457 0.0783 0.2529
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.007 0.0227
Plasmodium vivax plasmepsin IV, putative 0.0096 0.0059 0.0756
Schistosoma mansoni cathepsin C 0.0122 0.011 0.011
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0377 0.0624 0.5291
Trypanosoma cruzi cysteine peptidase, putative 0.0653 0.1178 0.3804
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Brugia malayi Papain family cysteine protease containing protein 0.0122 0.011 0.0356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Schistosoma mansoni calpain-2 (C02 family) 0.0102 0.007 0.007
Plasmodium vivax serine-repeat antigen (SERA) 0.0122 0.011 0.1406
Trypanosoma brucei antigen, putative 0.0377 0.0624 0.5291
Echinococcus granulosus calpain A 0.1095 0.2066 0.6669
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Brugia malayi calpain family protein 1 0.1027 0.193 0.6229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Plasmodium falciparum plasmepsin VI 0.0096 0.0059 0.0756
Giardia lamblia Cathepsin L-like protease 0.0122 0.011 0.1049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0321 0.051 0.4936
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0581 0.1034 0.3338
Giardia lamblia Cathepsin L precursor 0.0122 0.011 0.1049
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0096 0.0059 0.0191
Onchocerca volvulus 0.0457 0.0783 0.6687
Trypanosoma brucei Calpain-like protein 2 0.0102 0.007 0.0596
Echinococcus multilocularis tumor protein p63 0.0408 0.0686 0.2213
Giardia lamblia Cathepsin L-like protease 0.0122 0.011 0.1049
Leishmania major hypothetical protein, unknown function 0.0102 0.007 0.0596
Entamoeba histolytica cysteine protease, putative 0.0457 0.0783 1
Echinococcus granulosus cathepsin L cysteine protease 0.0258 0.0383 0.1237
Entamoeba histolytica calpain family cysteine protease, putative 0.0102 0.007 0.0897
Loa Loa (eye worm) hypothetical protein 0.0122 0.011 0.0356
Brugia malayi Papain family cysteine protease containing protein 0.0258 0.0383 0.1237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Entamoeba histolytica cysteine proteinase 2 0.0258 0.0383 0.489
Loa Loa (eye worm) hypothetical protein 0.0321 0.051 0.1648
Leishmania major calpain family cysteine protease-like protein 0.0102 0.007 0.0596
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0457 0.0783 0.2529
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0122 0.011 0.1406
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0122 0.011 0.1065
Brugia malayi cathepsin F-like cysteine proteinase 0.0136 0.0138 0.0447
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.1094 0.2064 0.2064
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0377 0.0624 0.2013
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.007 0.0227
Brugia malayi Cathepsin L-like precursor 0.0457 0.0783 0.2529
Onchocerca volvulus 0.0457 0.0783 0.6687
Schistosoma mansoni reticulocalbin 0.0068 0.0002 0.0002
Plasmodium falciparum cysteine proteinase falcipain 1 0.0258 0.0383 0.489
Echinococcus granulosus calbindin 32 0.0068 0.0002 0.0006
Onchocerca volvulus 0.0457 0.0783 0.6687
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0122 0.011 0.1049
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.2013
Loa Loa (eye worm) hypothetical protein 0.0122 0.011 0.0356
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Entamoeba histolytica cysteine protease, putative 0.0122 0.011 0.1406
Brugia malayi Cathepsin L-like precursor 0.0457 0.0783 0.2529
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0258 0.0383 0.3704
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.2013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.011 0.1065
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0102 0.007 0.0227
Toxoplasma gondii cathepsin B 0.0581 0.1034 1
Echinococcus granulosus cysteine protease 0.0258 0.0383 0.1237
Entamoeba histolytica hypothetical protein, conserved 0.0068 0.0002 0.0024
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0457 0.0783 0.2529
Echinococcus granulosus calumenin 0.0068 0.0002 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Giardia lamblia Cathepsin L precursor 0.0122 0.011 0.1049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.007 0.0679
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1608 0.3098 0.3098
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Giardia lamblia Cathepsin B precursor 0.0122 0.011 0.1049
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Echinococcus granulosus cathepsin b 0.1608 0.3098 1
Trypanosoma cruzi cysteine peptidase, putative 0.0457 0.0783 0.2529
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Toxoplasma gondii cathepsin CPC1 0.0122 0.011 0.1065
Echinococcus multilocularis cathepsin b 0.1608 0.3098 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.011 0.1065
Loa Loa (eye worm) hypothetical protein 0.0136 0.0138 0.0447
Entamoeba histolytica cysteine proteinase, putative 0.0321 0.051 0.6516
Trypanosoma cruzi centrin-3 0.0086 0.0039 0.0125
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0102 0.007 0.0679
Schistosoma mansoni cathepsin F (C01 family) 0.0321 0.051 0.051
Echinococcus multilocularis cathepsin L cysteine protease 0.0457 0.0783 0.2529
Schistosoma mansoni Mername-AA248 (C02 family) 0.0377 0.0624 0.0624
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.011 0.1065
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0102 0.007 0.0596
Echinococcus multilocularis EF hand domain containing family member A2 0.0068 0.0002 0.0006
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0102 0.007 0.0227
Schistosoma mansoni cathepsin s 0.0136 0.0138 0.0138
Giardia lamblia Cysteine protease 0.0122 0.011 0.1049
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0102 0.007 0.0227
Onchocerca volvulus 0.0068 0.0002 0.0016
Echinococcus multilocularis calpain 0.0377 0.0624 0.2013
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.5291
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0122 0.011 0.011
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.5291
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0096 0.0059 0.0059
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0122 0.011 0.1065
Schistosoma mansoni calpain-7 (C02 family) 0.0377 0.0624 0.0624
Echinococcus multilocularis calpain 5 0.0377 0.0624 0.2013
Trypanosoma brucei kinesin, putative 0.0275 0.0419 0.3553
Loa Loa (eye worm) hypothetical protein 0.1027 0.193 0.6229
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0227
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0457 0.0783 1
Trypanosoma brucei centrin-3 0.0086 0.0039 0.0328
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0122 0.011 0.1406
Leishmania major cathepsin L-like protease 0.0653 0.1178 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0258 0.0383 0.3704
Echinococcus multilocularis calcium uptake protein 1 0.0068 0.0002 0.0006
Entamoeba histolytica cysteine protease, putative 0.0122 0.011 0.1406
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Giardia lamblia Cathepsin B precursor 0.0581 0.1034 1
Toxoplasma gondii hypothetical protein 0.0102 0.007 0.0679
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0102 0.007 0.0596
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Toxoplasma gondii cathepsin CPL 0.0457 0.0783 0.7575
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0122 0.011 0.1406
Loa Loa (eye worm) hypothetical protein 0.0136 0.0138 0.0447
Echinococcus multilocularis calbindin 32 0.0068 0.0002 0.0006
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0258 0.0383 0.0383
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0457 0.0783 0.7575
Brugia malayi calpain D 0.0102 0.007 0.0227
Trypanosoma brucei calpain, putative 0.0102 0.007 0.0596
Giardia lamblia Cathepsin L precursor 0.0122 0.011 0.1049
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0457 0.0783 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0457 0.0783 0.2529
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0122 0.011 0.011
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Echinococcus multilocularis programmed cell death protein 0.0086 0.0039 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0122 0.011 0.1065
Entamoeba histolytica cysteine proteinase, putative 0.0258 0.0383 0.489
Entamoeba histolytica cysteine protease, putative 0.0122 0.011 0.1406
Leishmania major cathepsin L-like protease 0.0653 0.1178 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0321 0.051 0.1648
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0122 0.011 0.1065
Loa Loa (eye worm) hypothetical protein 0.0122 0.011 0.0356
Plasmodium falciparum serine repeat antigen 7 0.0122 0.011 0.1406
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0122 0.011 0.1065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0136 0.0138 0.0447
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.011 0.0356
Loa Loa (eye worm) calpain 5 0.0275 0.0419 0.1352
Giardia lamblia Cathepsin B precursor 0.0581 0.1034 1
Trypanosoma cruzi cysteine protease, putative 0.0258 0.0383 0.1237
Brugia malayi Cathepsin L-like precursor 0.0457 0.0783 0.2529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0258 0.0383 0.3251
Echinococcus granulosus cathepsin l cysteine peptidase 0.0457 0.0783 0.2529
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0122 0.011 0.1065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0457 0.0783 0.7575
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Brugia malayi Cathepsin L-like precursor 0.0457 0.0783 0.2529
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Plasmodium falciparum serine repeat antigen 5 0.0122 0.011 0.1406
Toxoplasma gondii cathepsin CPC2 0.0122 0.011 0.1065
Schistosoma mansoni cathepsin F (C01 family) 0.0457 0.0783 0.0783
Trichomonas vaginalis calcineurin B subunit, putative 0.0068 0.0002 0.0018
Echinococcus granulosus calpain A 0.0377 0.0624 0.2013
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0377 0.0624 0.5291
Entamoeba histolytica cysteine proteinase, putative 0.0258 0.0383 0.489
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Trichomonas vaginalis calcium binding protein, putative 0.0086 0.0039 0.0373
Giardia lamblia Cathepsin B precursor 0.0122 0.011 0.1049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0258 0.0383 0.3251
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0122 0.011 0.1049
Trypanosoma brucei Calpain-like protein 1.2 0.0102 0.007 0.0596
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0108 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0653 0.1178 1
Leishmania major cathepsin L-like protease 0.0457 0.0783 0.6648
Trichomonas vaginalis calpain, putative 0.0102 0.007 0.0679
Brugia malayi cathepsin L-like precursor 0.0321 0.051 0.1648
Entamoeba histolytica cysteine protease, putative 0.0258 0.0383 0.489
Loa Loa (eye worm) ctsf protein 0.0457 0.0783 0.2529
Plasmodium falciparum cysteine proteinase falcipain 3 0.0457 0.0783 1
Onchocerca volvulus 0.0122 0.011 0.0941
Toxoplasma gondii calcium-dependent protein kinase 0.0068 0.0002 0.0018
Trypanosoma brucei cysteine peptidase C (CPC) 0.0581 0.1034 0.8777
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.1094 0.2064 0.6663
Trypanosoma cruzi cysteine peptidase, putative 0.0653 0.1178 0.3804
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0102 0.007 0.0227
Echinococcus multilocularis cysteine protease 0.0457 0.0783 0.2529
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0457 0.0783 0.7575
Entamoeba histolytica grainin 2 0.0086 0.0039 0.0493

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 11.2202 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Agonists. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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