Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0052 | 0.1564 | 0.1601 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0925 | 0.0946 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0056 | 0.1689 | 0.1729 |
Echinococcus granulosus | tar DNA binding protein | 0.0052 | 0.1564 | 0.1827 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0034 | 0.0876 | 0.0806 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0035 | 0.0925 | 0.0877 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0052 | 0.1564 | 0.1475 |
Mycobacterium ulcerans | monooxygenase | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | Pre-SET motif family protein | 0.0035 | 0.0925 | 0.0811 |
Mycobacterium tuberculosis | Possible electron transfer protein FdxB | 0.0023 | 0.0463 | 0.0283 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0141 | 0.4872 | 1 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.0124 | 0.4215 | 0.5767 |
Plasmodium falciparum | ferredoxin--NADP reductase | 0.0023 | 0.0463 | 0.0191 |
Trichomonas vaginalis | set domain proteins, putative | 0.0279 | 1 | 1 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Giardia lamblia | Flavohemoprotein lateral transfer candidate | 0.0023 | 0.0463 | 0.0218 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0056 | 0.1689 | 0.2013 |
Brugia malayi | glutathione reductase | 0.0056 | 0.1689 | 0.1605 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | flavodoxin family protein | 0.02 | 0.7063 | 0.7189 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0077 | 0.2465 | 0.3166 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Leishmania major | p450 reductase, putative | 0.02 | 0.7063 | 1 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Mycobacterium ulcerans | flavodoxin reductase Hmp | 0.0023 | 0.0463 | 0.0445 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Echinococcus multilocularis | methionine synthase reductase | 0.0124 | 0.4215 | 0.5767 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0056 | 0.1689 | 0.222 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Schistosoma mansoni | NADH-cytochrome B5 reductase | 0.0023 | 0.0463 | 0.0191 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0334 | 0.0198 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0925 | 0.0877 |
Brugia malayi | TAR-binding protein | 0.0052 | 0.1564 | 0.1475 |
Mycobacterium ulcerans | electron transfer protein FdxB | 0.0023 | 0.0463 | 0.0445 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0178 | 0.6217 | 0.8742 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0035 | 0.0925 | 0.1983 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Possible oxygenase | 0.0023 | 0.0463 | 0.0283 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Leishmania major | NADH-dependent fumarate reductase-like protein | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Plasmodium falciparum | flap endonuclease 1 | 0.0031 | 0.0758 | 0.0629 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | oxidoreductase-protein, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0023 | 0.0463 | 0.0445 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0019 | 0.0334 | 0.0259 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0141 | 0.4872 | 1 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.02 | 0.7063 | 1 |
Echinococcus multilocularis | NADH cytochrome b5 reductase 3 | 0.0023 | 0.0463 | 0.0191 |
Echinococcus granulosus | flap endonuclease 1 | 0.0031 | 0.0758 | 0.0629 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0334 | 0.5 |
Mycobacterium tuberculosis | Probable monooxygenase | 0.0023 | 0.0463 | 0.0283 |
Echinococcus multilocularis | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0191 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0141 | 0.4872 | 1 |
Leishmania major | nitrate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0178 | 0.6217 | 1 |
Mycobacterium ulcerans | flavodoxin oxidoreductase | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0012 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0101 | 0.3368 | 0.4508 |
Trypanosoma cruzi | oxidoreductase-protein, putative | 0.0023 | 0.0463 | 0.0445 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium vivax | ferredoxin--NADP reductase, putative | 0.0023 | 0.0463 | 0.0191 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Trypanosoma cruzi | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.0031 | 0.0758 | 0.0775 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.02 | 0.7063 | 1 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0191 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.02 | 0.7063 | 1 |
Leishmania major | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.0031 | 0.0758 | 0.0438 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0099 | 0.3311 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0141 | 0.4872 | 1 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Chlamydia trachomatis | sulfite reductase | 0.0124 | 0.4215 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0925 | 0.0877 |
Mycobacterium tuberculosis | Probable reductase | 0.0127 | 0.4344 | 0.8837 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Plasmodium vivax | glutathione reductase, putative | 0.0056 | 0.1689 | 0.2013 |
Trypanosoma brucei | NADH-cytochrome b5 reductase-like protein | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.02 | 0.7063 | 1 |
Trypanosoma cruzi | p450 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0334 | 0.5 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0056 | 0.1689 | 0.2985 |
Schistosoma mansoni | flap endonuclease-1 | 0.0028 | 0.0648 | 0.0466 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0035 | 0.0925 | 0.0877 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0334 | 0.0259 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0124 | 0.4215 | 0.4314 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0273 | 0.9769 | 1 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Echinococcus multilocularis | tar DNA binding protein | 0.0052 | 0.1564 | 0.1827 |
Toxoplasma gondii | ferredoxin NADP+ oxidoreductase FNR | 0.0023 | 0.0463 | 0.0431 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium vivax | SET domain protein, putative | 0.0035 | 0.0925 | 0.0877 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0334 | 0.0259 |
Echinococcus granulosus | NADH cytochrome b5 reductase 3 | 0.0023 | 0.0463 | 0.0191 |
Plasmodium vivax | hypothetical protein, conserved | 0.0077 | 0.2465 | 0.3166 |
Leishmania major | trypanothione reductase | 0.0056 | 0.1689 | 0.222 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0035 | 0.0925 | 0.0877 |
Trypanosoma brucei | trypanothione reductase | 0.0056 | 0.1689 | 0.222 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma cruzi | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.02 | 0.7063 | 1 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Giardia lamblia | Hypothetical protein | 0.0178 | 0.6217 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Leishmania major | hypothetical protein, conserved | 0.0077 | 0.2465 | 0.3343 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma cruzi | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.02 | 0.7063 | 1 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.0031 | 0.0758 | 0.1422 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0127 | 0.4344 | 0.8837 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.0031 | 0.0758 | 0.0872 |
Onchocerca volvulus | 0.0035 | 0.0925 | 0.0484 | |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Trypanosoma brucei | nitrate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium ulcerans | oxygenase | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Plasmodium falciparum | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0191 |
Leishmania major | reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0077 | 0.2465 | 1 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.02 | 0.7063 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0334 | 0.0259 |
Toxoplasma gondii | thioredoxin reductase | 0.0056 | 0.1689 | 0.455 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0077 | 0.2465 | 0.3343 |
Loa Loa (eye worm) | TAR-binding protein | 0.0052 | 0.1564 | 0.1601 |
Trypanosoma cruzi | nitrate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium falciparum | thioredoxin reductase | 0.0056 | 0.1689 | 0.2013 |
Trypanosoma brucei | NADH-dependent fumarate reductase | 0.0023 | 0.0463 | 0.0445 |
Schistosoma mansoni | tar DNA-binding protein | 0.0052 | 0.1564 | 0.1827 |
Leishmania major | oxidoreductase-like protein | 0.0023 | 0.0463 | 0.0445 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0012 |
Schistosoma mansoni | cytochrome B5 | 0.0023 | 0.0463 | 0.0191 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Trichomonas vaginalis | sulfite reductase, putative | 0.02 | 0.7063 | 0.6962 |
Brugia malayi | FAD binding domain containing protein | 0.02 | 0.7063 | 0.7189 |
Brugia malayi | Pre-SET motif family protein | 0.0245 | 0.874 | 0.893 |
Leishmania major | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0035 | 0.0925 | 0.0877 |
Trypanosoma cruzi | p450 reductase, putative | 0.02 | 0.7063 | 1 |
Brugia malayi | Flap endonuclease-1 | 0.0031 | 0.0758 | 0.0638 |
Brugia malayi | diaphorase | 0.0023 | 0.0463 | 0.0331 |
Trypanosoma brucei | NADH-cytochrome b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0077 | 0.2465 | 0.3343 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0035 | 0.0925 | 0.0877 |
Brugia malayi | RNA binding protein | 0.0052 | 0.1564 | 0.1475 |
Brugia malayi | FAD binding domain containing protein | 0.0124 | 0.4215 | 0.4229 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0334 | 0.0259 |
Echinococcus granulosus | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0191 |
Schistosoma mansoni | cytochrome P450 reductase | 0.02 | 0.7063 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0159 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0334 | 0.0259 |
Chlamydia trachomatis | Na(+)-translocating NADH-quinone reductase subunit F | 0.0023 | 0.0463 | 0.0331 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0334 | 0.0259 |
Trypanosoma cruzi | reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Loa Loa (eye worm) | RNA binding protein | 0.0052 | 0.1564 | 0.1601 |
Loa Loa (eye worm) | diaphorase | 0.0023 | 0.0463 | 0.0473 |
Mycobacterium ulcerans | oxidoreductase | 0.0023 | 0.0463 | 0.0445 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0127 | 0.4344 | 0.8837 |
Treponema pallidum | ferredoxin-NADP(+) reductase subunit alpha | 0.0023 | 0.0463 | 0.0602 |
Brugia malayi | Thioredoxin reductase | 0.0056 | 0.1689 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.7063 | 0.723 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0127 | 0.4344 | 0.8837 |
Leishmania major | cytochrome-b5 reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Trypanosoma brucei | NADH-dependent fumarate reductase, putative | 0.0023 | 0.0463 | 0.0445 |
Plasmodium vivax | oxidoreductase NAD-binding domain containing protein | 0.0023 | 0.0463 | 0.0191 |
Treponema pallidum | flavodoxin | 0.0077 | 0.2465 | 1 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0077 | 0.2465 | 0.3343 |
Plasmodium falciparum | glutathione reductase | 0.0056 | 0.1689 | 0.2013 |
Toxoplasma gondii | NADH-cytochrome b5 reductase 1, putative | 0.0023 | 0.0463 | 0.0431 |
Echinococcus granulosus | methionine synthase reductase | 0.0124 | 0.4215 | 0.5767 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0077 | 0.2465 | 0.3166 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.02 | 0.7063 | 1 |
Brugia malayi | Cytochrome b5-like Heme/Steroid binding domain containing protein | 0.0023 | 0.0463 | 0.0331 |
Plasmodium vivax | flap endonuclease 1, putative | 0.0031 | 0.0758 | 0.0629 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0077 | 0.2465 | 0.2523 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0056 | 0.1689 | 0.2013 |
Leishmania major | cytochrome P450 reductase, putative | 0.0178 | 0.6217 | 0.8774 |
Brugia malayi | flavodoxin family protein | 0.0077 | 0.2465 | 0.2411 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0178 | 0.6217 | 0.6086 |
Loa Loa (eye worm) | glutathione reductase | 0.0056 | 0.1689 | 0.1729 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.02 | 0.7063 | 0.723 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0056 | 0.1689 | 0.2013 |
Brugia malayi | follicle stimulating hormone receptor | 0.0273 | 0.9769 | 1 |
Mycobacterium tuberculosis | Hypothetical oxidoreductase | 0.0023 | 0.0463 | 0.0283 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.02 | 0.7063 | 1 |
Giardia lamblia | Flap structure-specific endonuclease | 0.0031 | 0.0758 | 0.072 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0031 | 0.0758 | 0.0629 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.02 | 0.7063 | 1 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.02 | 0.7063 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0023 | 0.0463 | 0.0283 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.02 | 0.7063 | 1 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.0031 | 0.0758 | 0.0872 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0015 | 0.0155 | 0.0159 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0077 | 0.2465 | 0.3343 |
Loa Loa (eye worm) | cytochrome b5 reductase 4 | 0.0023 | 0.0463 | 0.0473 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.0099 | 0.3311 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0015 | 0.0155 | 0.0159 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0077 | 0.2465 | 0.2204 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0127 | 0.4344 | 0.8837 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0127 | 0.4344 | 0.8837 |
Schistosoma mansoni | diflavin oxidoreductase | 0.0099 | 0.3311 | 0.4424 |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.0031 | 0.0758 | 0.0872 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0245 | 0.874 | 0.8946 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 0.0001 M | In vitro inhibitory activity of the compound towards partially purified human placenta aldose reductase | ChEMBL. | 3121857 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.