Detailed information for compound 1632783

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 422.432 | Formula: C17H14N2O7S2
  • H donors: 3 H acceptors: 7 LogP: 3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1c(/N=N/c2ccccc2C)c2ccc(cc2cc1S(=O)(=O)O)S(=O)(=O)O
  • InChi: 1S/C17H14N2O7S2/c1-10-4-2-3-5-14(10)18-19-16-13-7-6-12(27(21,22)23)8-11(13)9-15(17(16)20)28(24,25)26/h2-9,20H,1H3,(H,21,22,23)(H,24,25,26)/b19-18+
  • InChiKey: ABTIMDCFDYKWSF-VHEBQXMUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0432 0.059 0.059
Loa Loa (eye worm) hypothetical protein 0.1365 0.1991 0.1986
Loa Loa (eye worm) hypothetical protein 0.0835 0.1195 0.1189
Schistosoma mansoni voltage-gated potassium channel 0.0164 0.0187 0.0181
Onchocerca volvulus 0.0432 0.059 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.1798 0.264 0.264
Trichomonas vaginalis PIKK family atypical protein kinase 0.3964 0.5892 0.5892
Echinococcus granulosus nervana 2 0.0063 0.0036 0.0029
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0112 0.0109 0.5
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0432 0.059 0.0584
Echinococcus granulosus Glutaredoxin protein 5 0.0063 0.0036 0.0029
Echinococcus multilocularis serine protein kinase ATM 0.1267 0.1844 0.1838
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0432 0.059 1
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0432 0.059 0.0555
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.67 1 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0432 0.059 0.0584
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2247 0.3315 0.3241
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0432 0.059 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.5721 0.8529 0.8529
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0432 0.059 0.0555
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0112 0.0109 0.0109
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0432 0.059 0.0584
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0432 0.059 0.0689
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.098 0.1412 0.1407
Trichomonas vaginalis PIKK family atypical protein kinase 0.5329 0.7942 0.7942
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0432 0.059 0.0584
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0432 0.059 0.0584
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1267 0.1844 0.1838
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Echinococcus multilocularis Zinc finger, PHD finger 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.3618 0.5373 0.5373
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1267 0.1844 0.1838
Trichomonas vaginalis PIKK family atypical protein kinase 0.3618 0.5373 0.5373
Entamoeba histolytica hypothetical protein 0.0432 0.059 0.0555
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Trichomonas vaginalis immunophilin, putative 0.0112 0.0109 0.0109
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0555
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.67 1 1
Leishmania major phosphatidylinositol kinase related protein, putative 0.0432 0.059 0.0487
Loa Loa (eye worm) hypothetical protein 0.0432 0.059 0.0584
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.0432 0.059 0.0555
Loa Loa (eye worm) AGC/AKT protein kinase 0.0102 0.0095 0.0088
Brugia malayi p70 ribosomal S6 kinase beta 0.0096 0.0085 0.0079
Leishmania major phosphatidylinositol kinase, putative 0.0432 0.059 0.0487
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0112 0.0109 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.098 0.1412 0.1412
Trichomonas vaginalis PIKK family atypical protein kinase 0.4004 0.5952 0.5952
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0835 0.1195 0.1162
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0432 0.059 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0432 0.059 0.5
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0432 0.059 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.3964 0.5892 0.5892
Echinococcus multilocularis fk506 binding protein 0.0112 0.0109 0.0103
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0432 0.059 0.05
Trichomonas vaginalis PIKK family atypical protein kinase 0.3612 0.5364 0.5364
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0432 0.059 0.0584
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0432 0.059 0.0584
Echinococcus multilocularis 0.0432 0.059 0.0584
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0112 0.0109 0.0072
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0112 0.0109 0.0072
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.2247 0.3315 0.331
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2247 0.3315 0.329
Entamoeba histolytica protein kinase, putative 0.0102 0.0095 0.0058
Echinococcus granulosus serine protein kinase ATM 0.1267 0.1844 0.1838
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0112 0.0109 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Trypanosoma cruzi Protein kinase B 0.007 0.0046 0.0009
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.015 0.0166 0.016
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0432 0.059 0.0584
Schistosoma mansoni hypothetical protein 0.0432 0.059 0.0584
Echinococcus multilocularis rac serine:threonine kinase 0.007 0.0046 0.004
Trichomonas vaginalis conserved hypothetical protein 0.1412 0.2061 0.2061
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0432 0.059 0.05
Loa Loa (eye worm) hypothetical protein 0.098 0.1412 0.1407
Trichomonas vaginalis PIKK family atypical protein kinase 0.67 1 1
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0112 0.0109 0.0072
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1267 0.1844 0.1838
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2247 0.3315 0.329
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0432 0.059 0.0555
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1267 0.1844 0.1814
Leishmania major phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0487
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0432 0.059 0.0584
Giardia lamblia GTOR 0.67 1 1
Toxoplasma gondii FATC domain-containing protein 0.1267 0.1844 0.2397
Trichomonas vaginalis PIKK family atypical protein kinase 0.2247 0.3315 0.3315
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0432 0.059 0.059
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.4004 0.5952 0.5952
Trichomonas vaginalis PIKK family atypical protein kinase 0.3612 0.5364 0.5364
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0112 0.0109 0.0109
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0112 0.0109 0.0015
Trypanosoma brucei target of rapamycin kinase 3, putative 0.5335 0.795 0.7931
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0432 0.059 0.05
Trichomonas vaginalis PIKK family atypical protein kinase 0.0835 0.1195 0.1195
Trichomonas vaginalis PIKK family atypical protein kinase 0.1267 0.1844 0.1844
Brugia malayi Protein kinase domain containing protein 0.0102 0.0095 0.0088
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.05
Plasmodium vivax hypothetical protein, conserved 0.0432 0.059 1
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.0432 0.059 0.059
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.67 1 1
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0112 0.0109 0.0103
Loa Loa (eye worm) phosphatidylinositol 3 0.67 1 1
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0112 0.0109 0.0072
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.5335 0.795 0.7928
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0432 0.059 0.0555
Loa Loa (eye worm) hypothetical protein 0.0096 0.0086 0.0079
Schistosoma mansoni immunophilin 0.0096 0.0086 0.0079
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1267 0.1844 0.1814
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0432 0.059 0.0584
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0432 0.059 0.0689
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0063 0.0036 0.0029
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.014 0.0152 0.0152
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0112 0.0109 0.0072
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0555
Loa Loa (eye worm) hypothetical protein 0.0432 0.059 0.0584
Schistosoma mansoni voltage-gated potassium channel 0.0164 0.0187 0.0181
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.67 1 1
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0432 0.059 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0432 0.059 0.059
Echinococcus multilocularis nervana 2 0.0063 0.0036 0.0029
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0555
Trichomonas vaginalis PIKK family atypical protein kinase 0.2247 0.3315 0.3315
Entamoeba histolytica hypothetical protein 0.1267 0.1844 0.1814
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0432 0.059 0.0555
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0432 0.059 0.0584
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0432 0.059 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.67 1 1
Echinococcus multilocularis Glutaredoxin protein 5 0.0063 0.0036 0.0029
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0432 0.059 0.0584
Entamoeba histolytica PH domain containing protein kinase, putative 0.007 0.0046 0.0009
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.2783 0.4119 0.4063
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0432 0.059 0.0487
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2247 0.3315 0.3251
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0432 0.059 0.0689
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0096 0.0086 0.0079
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0112 0.0109 0.1304
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0432 0.059 0.0555
Trichomonas vaginalis conserved hypothetical protein 0.0835 0.1195 0.1195
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2247 0.3315 0.331
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0112 0.0109 0.0103
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.67 1 1
Onchocerca volvulus 0.0432 0.059 0.5
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0432 0.059 0.0584
Echinococcus granulosus potassium voltage gated channel subfamily H 0.015 0.0166 0.016
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0112 0.0109 0.1304
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.435 0.6471 0.6471
Trichomonas vaginalis PIKK family atypical protein kinase 0.2247 0.3315 0.3315
Echinococcus granulosus serine/threonine protein kinase 0.007 0.0046 0.004
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0432 0.059 0.0689
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0432 0.059 0.0584
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.67 1 1
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Leishmania major phosphatidylinositol 3-kinase, putative 0.2247 0.3315 0.3241
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0432 0.059 0.059
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0112 0.0109 0.0103
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.67 1 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.007 0.0046 0.0009
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.3169 0.4698 0.4648
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.5329 0.7942 0.7942
Loa Loa (eye worm) FKBP5 protein 0.0112 0.0109 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0432 0.059 0.059
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0064 0.0037 0.003
Trypanosoma cruzi rac serine-threonine kinase, putative 0.007 0.0046 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.2247 0.3315 0.3315
Trichomonas vaginalis PIKK family atypical protein kinase 0.1267 0.1844 0.1844
Entamoeba histolytica hypothetical protein 0.0432 0.059 0.0555
Echinococcus granulosus nervana 2 0.0063 0.0036 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0432 0.059 0.059
Trichomonas vaginalis PIKK family atypical protein kinase 0.3618 0.5373 0.5373
Leishmania major phosphatidylinositol 4-kinase, putative 0.0432 0.059 0.0487
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0432 0.059 0.0584
Loa Loa (eye worm) hypothetical protein 0.1267 0.1844 0.1838
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0432 0.059 0.059
Loa Loa (eye worm) phosphatidylinositol kinase 0.0432 0.059 0.0584
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.67 1 1
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0432 0.059 1
Schistosoma mansoni serine/threonine-protein kinase 0.007 0.0046 0.004
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0555
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0432 0.059 0.059
Giardia lamblia Phosphatidylinositol 4-kinase 0.0432 0.059 0.0555
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0112 0.0109 0.0103
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1267 0.1844 0.1766
Leishmania major hypothetical protein, conserved 0.0432 0.059 0.0487
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1267 0.1844 0.1838
Trichomonas vaginalis PIKK family atypical protein kinase 0.5329 0.7942 0.7942
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0432 0.059 0.0555
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0432 0.059 0.0584
Entamoeba histolytica protein kinase, putative 0.0096 0.0085 0.0048
Trypanosoma cruzi target of rapamycin kinase 3 0.5335 0.795 0.7943
Echinococcus granulosus serine threonine protein kinase nrc 0.0064 0.0037 0.003
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.015 0.0166 0.016
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0555
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.015 0.0166 0.016
Trichomonas vaginalis PIKK family atypical protein kinase 0.4004 0.5952 0.5952
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.2247 0.3315 0.331
Loa Loa (eye worm) phosphatidylinositol 3 0.0432 0.059 0.0584
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0432 0.059 0.059
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.67 1 1
Mycobacterium leprae conserved hypothetical protein 0.0432 0.059 0.5
Schistosoma mansoni serine/threonine-protein kinase 0.007 0.0046 0.004
Trichomonas vaginalis fk506-binding protein, putative 0.0112 0.0109 0.0109
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.67 1 1
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0432 0.059 0.0555
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0432 0.059 0.0555
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.2247 0.3315 0.331
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0432 0.059 0.059
Schistosoma mansoni immunophilin 0.0112 0.0109 0.0103
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0064 0.0037 0.003
Loa Loa (eye worm) phosphatidylinositol 3 0.2247 0.3315 0.331
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2247 0.3315 0.3251
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.5329 0.7942 0.7942
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0432 0.059 0.0584
Loa Loa (eye worm) phosphatidylinositol 3 0.0432 0.059 0.0584
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0432 0.059 0.0555
Toxoplasma gondii target of rapamycin (TOR), putative 0.4983 0.7422 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0096 0.0085 0.0079
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0432 0.059 0.0584
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0432 0.059 0.0555
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0112 0.0109 0.5
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.67 1 1
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1412 0.2061 0.2693
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0096 0.0086 0.0079
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0432 0.059 0.0584
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0432 0.059 0.0555
Entamoeba histolytica protein kinase, putative 0.0102 0.0095 0.0058
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0432 0.059 0.0584
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0432 0.059 0.0689
Schistosoma mansoni immunophilin 0.0112 0.0109 0.0103
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0112 0.0109 0.0015
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.67 1 1
Loa Loa (eye worm) hypothetical protein 0.1412 0.2061 0.2056
Echinococcus multilocularis nervana 2 0.0063 0.0036 0.0029
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0432 0.059 1
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.098 0.1412 0.1407
Leishmania major hypothetical protein, unknown function 0.0432 0.059 0.0487
Giardia lamblia Hypothetical protein 0.0432 0.059 0.0555
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0432 0.059 0.0555
Schistosoma mansoni fkbp-rapamycin associated protein 0.1267 0.1844 0.1838
Brugia malayi FAT domain containing protein 0.098 0.1412 0.1407
Trichomonas vaginalis PIKK family atypical protein kinase 0.4494 0.6688 0.6688
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0432 0.059 0.0584
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.014 0.0152 0.0152
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0432 0.059 0.0584
Trichomonas vaginalis PIKK family atypical protein kinase 0.1267 0.1844 0.1844
Trichomonas vaginalis PIKK family atypical protein kinase 0.4983 0.7422 0.7422
Entamoeba histolytica hypothetical protein 0.0432 0.059 0.0555
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0432 0.059 0.059
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1267 0.1844 0.1838
Loa Loa (eye worm) phosphatidylinositol 3 0.0432 0.059 0.0584
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0112 0.0109 0.0072
Loa Loa (eye worm) phosphatidylinositol 3 0.0432 0.059 0.0584
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0112 0.0109 0.0103
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0432 0.059 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.3612 0.5364 0.5364
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0432 0.059 0.0555
Loa Loa (eye worm) hypothetical protein 0.013 0.0137 0.013
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0432 0.059 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.3618 0.5373 0.5373
Trichomonas vaginalis PIKK family atypical protein kinase 0.5329 0.7942 0.7942
Entamoeba histolytica protein kinase rad3, putative 0.1267 0.1844 0.1814
Trichomonas vaginalis PIKK family atypical protein kinase 0.2247 0.3315 0.3315
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0432 0.059 0.0584
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0112 0.0109 0.0072
Entamoeba histolytica hypothetical protein 0.0432 0.059 0.0555
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.1267 0.1844 0.1814
Schistosoma mansoni hypothetical protein 0.098 0.1412 0.1407
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0063 0.0036 0.0029
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0112 0.0109 0.0103
Trichomonas vaginalis AGC family protein kinase 0.0102 0.0095 0.0095
Plasmodium vivax hypothetical protein 0.0432 0.059 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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