Detailed information for compound 1644543

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 350.324 | Formula: C16H11N2NaO4S
  • H donors: 2 H acceptors: 4 LogP: 3.34 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1/N=N/c1ccccc1)ccc(c2)S(=O)(=O)[O-].[Na+]
  • InChi: 1S/C16H12N2O4S.Na/c19-15-9-6-11-10-13(23(20,21)22)7-8-14(11)16(15)18-17-12-4-2-1-3-5-12;/h1-10,19H,(H,20,21,22);/q;+1/p-1/b18-17+;
  • InChiKey: YOCIQNIEQYCORH-ZAGWXBKKSA-M  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0027 0.0071 0.0093
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Mycobacterium tuberculosis Serine/threonine-protein kinase PknG (protein kinase G) (STPK G) 0.0013 0 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.0093 0.0405 0.0405
Toxoplasma gondii RING zinc finger protein 0.0027 0.0071 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0024 0.0024
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0025 0.0062 0.0062
Loa Loa (eye worm) phosphatidylinositol 3 0.0032 0.0094 0.0094
Echinococcus multilocularis fmrfamide receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0093 0.0405 0.0405
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0538 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0093 0.0405 0.0405
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Schistosoma mansoni amine GPCR 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Trichomonas vaginalis hypothetical protein 0.0027 0.0071 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0538 0.269 0.269
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Brugia malayi G protein-coupled receptor F59B2.13 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0538 0.269 0.269
Brugia malayi GnHR receptor homolog 0.0093 0.0405 0.0405
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0027 0.0071 0.0071
Echinococcus multilocularis serotonin receptor 0.0179 0.0847 0.0847
Leishmania major hypothetical protein, conserved 0.0538 0.269 0.269
Brugia malayi putative neuropeptide receptor 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0538 0.269 0.3499
Echinococcus multilocularis neuropeptide Y receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis SWI:SNF matrix associated 0.1514 0.7686 0.7686
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0161 0.0757 0.0757
Brugia malayi larval opioid receptor 0.0093 0.0405 0.0405
Echinococcus granulosus fmrfamide receptor 0.0093 0.0405 0.0405
Plasmodium vivax zinc finger protein, putative 0.0027 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Plasmodium vivax DNA repair protein RAD5, putative 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0093 0.0405 0.0527
Trypanosoma cruzi WLM domain containing protein, putative 0.0538 0.269 0.269
Trypanosoma cruzi hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0093 0.0405 0.0405
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0093 0.0405 0.0405
Brugia malayi hypothetical protein 0.0027 0.0071 0.0071
Trichomonas vaginalis ankyrin, putative 0.0027 0.0071 0.0071
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase I PknI (protein kinase I) (STPK I) (phosphorylase B kinase kinase) (hydro 0.0013 0 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Trypanosoma brucei hypothetical protein, conserved 0.0538 0.269 0.269
Schistosoma mansoni hypothetical protein 0.0025 0.0062 0.0062
Brugia malayi Zinc finger, C2H2 type family protein 0.0027 0.0071 0.0071
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0071 0.0071
Schistosoma mansoni myosin xvIII 0.0093 0.0405 0.0405
Echinococcus granulosus zinc finger protein Ran binding 0.0538 0.269 0.269
Schistosoma mansoni mind bomb 0.0027 0.0071 0.0071
Brugia malayi neuropeptide F receptor 0.0093 0.0405 0.0405
Plasmodium falciparum RING zinc finger protein, putative 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi hypoxia-induced factor 1 0.0107 0.0477 0.0477
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Leishmania major hypothetical protein 0.0027 0.0071 0.0071
Chlamydia trachomatis SWIB complex protein 0.1514 0.7686 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0093 0.0405 0.0405
Schistosoma mansoni biogenic amine (5HT) receptor 0.0179 0.0847 0.0847
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0018 0.0024 0.0024
Schistosoma mansoni peter pan-related 0.0027 0.0071 0.0071
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0093 0.0405 0.0405
Plasmodium vivax RING zinc finger protein, putative 0.0027 0.0071 0.0071
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0093 0.0405 0.0405
Brugia malayi G-protein coupled receptor 0.0093 0.0405 0.0405
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0032 0.0094 0.0094
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni protein kinase 0.1965 1 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0071 0.0071
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0538 0.269 0.269
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0062
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Echinococcus granulosus Zinc finger RanBP2 type 0.0538 0.269 0.269
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0115 0.0115
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0093 0.0405 0.0405
Echinococcus granulosus cGMP dependent protein kinase 0.0018 0.0024 0.0024
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0093 0.0405 0.0405
Brugia malayi hypothetical protein 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypoxia-induced factor 1 0.0107 0.0477 0.0477
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Schistosoma mansoni amine GPCR 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0093 0.0405 0.0405
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1514 0.7686 0.7686
Echinococcus multilocularis somatostatin receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0071 0.0071
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0538 0.269 0.269
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Echinococcus multilocularis ring finger protein 170 0.0027 0.0071 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Brugia malayi neuropeptide F receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0093 0.0405 0.0405
Toxoplasma gondii hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus ring finger protein 170 0.0027 0.0071 0.0071
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis ring finger protein 113a 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Leishmania major casein kinase II, putative 0.1965 1 1
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0061 0.0061
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0027 0.0071 0.0071
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0027 0.0071 0.0071
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0103 0.0103
Echinococcus multilocularis expressed conserved protein 0.0018 0.0024 0.0024
Giardia lamblia GTOR 0.0032 0.0094 0.0094
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0538 0.269 0.269
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Echinococcus granulosus RING finger protein 185 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi RE15519p 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0538 0.269 0.269
Echinococcus multilocularis SWI:SNF matrix associated 0.1514 0.7686 0.7686
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0028 0.0028
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0017 0.0017 0.0017
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0032 0.0094 0.0094
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1514 0.7686 0.7686
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Loa Loa (eye worm) brahma associated protein 0.1514 0.7686 0.7686
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0538 0.269 0.3499
Loa Loa (eye worm) TYRA-2 protein 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Onchocerca volvulus 0.0093 0.0405 0.0527
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Echinococcus granulosus neuropeptide receptor A26 0.0093 0.0405 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Brugia malayi B-box zinc finger family protein 0.0027 0.0071 0.0071
Echinococcus multilocularis ring and YY1 binding protein 0.0538 0.269 0.269
Schistosoma mansoni hypothetical protein 0.0538 0.269 0.269
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Toxoplasma gondii ran binding protein 0.0538 0.269 0.269
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0538 0.269 0.269
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.0405 0.0405
Echinococcus granulosus alpha 1A adrenergic receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Echinococcus granulosus dro:myosuppressin receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0179 0.0847 0.0847
Echinococcus granulosus neuropeptide Y receptor 0.0093 0.0405 0.0405
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0027 0.0071 0.0071
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) G-protein coupled receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0032 0.0094 0.0094
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Brugia malayi RING finger protein 20 0.0027 0.0071 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Brugia malayi hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus tachykinin peptides receptor 99D 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0093 0.0405 0.0527
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0025 0.0061 0.0061
Trypanosoma brucei DNA repair protein, putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0045 0.0045
Echinococcus granulosus orexin receptor type 2 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Echinococcus granulosus biogenic amine 5HT receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Brugia malayi Dopamine receptor protein 2 0.0093 0.0405 0.0405
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0132 0.0132
Plasmodium vivax trophozoite exported protein 1, putative 0.0027 0.0071 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0027 0.0071 0.0071
Schistosoma mansoni alpha-1 adrenergic receptor 0.0093 0.0405 0.0405
Brugia malayi SWIB/MDM2 domain containing protein 0.1514 0.7686 0.7686
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Brugia malayi follicle stimulating hormone receptor 0.0256 0.124 0.124
Onchocerca volvulus 0.0027 0.0071 0.0093
Schistosoma mansoni hypothetical protein 0.1514 0.7686 0.7686
Echinococcus granulosus hypothetical protein 0.0093 0.0405 0.0405
Schistosoma mansoni single-minded 0.0034 0.0108 0.0108
Echinococcus granulosus sex peptide receptor 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0103 0.0103
Plasmodium vivax unspecified product 0.1965 1 1
Echinococcus granulosus tumor protein p63 0.1776 0.903 0.903
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Toxoplasma gondii hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0538 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0538 0.269 0.269
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Trypanosoma brucei Casein kinase II 0.1965 1 1
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0027 0.0071 0.0071
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0093 0.0405 0.0405
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0015 0.0008 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Echinococcus granulosus g-protein coupled receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.1514 0.7686 0.7686
Brugia malayi hypothetical protein 0.0116 0.0523 0.0523
Echinococcus multilocularis neuropeptide s receptor 0.0093 0.0405 0.0405
Giardia lamblia Ser/Thr protein kinase 0.0027 0.0071 0.0071
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0093 0.0405 0.0405
Brugia malayi Melatonin receptor type 1A 0.0093 0.0405 0.0405
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.0405 0.0405
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0538 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Giardia lamblia Kinase, NEK 0.0041 0.014 0.014
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Onchocerca volvulus 0.0027 0.0071 0.0093
Brugia malayi Egg laying defective protein 4 0.0018 0.0024 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.014 0.014
Echinococcus granulosus ring and YY1 binding protein 0.0538 0.269 0.269
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.026 0.1263 0.1263
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0024 0.0024
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.0405 0.0405
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0115 0.0115
Onchocerca volvulus 0.0093 0.0405 0.0527
Schistosoma mansoni neuropeptide receptor 0.0093 0.0405 0.0405
Echinococcus granulosus neuropeptide s receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Brugia malayi AKH receptor 0.0093 0.0405 0.0405
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1514 0.7686 0.7686
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0032 0.0094 0.0094
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0538 0.269 0.269
Schistosoma mansoni hypothetical protein 0.0093 0.0405 0.0405
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0115 0.0115
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Toxoplasma gondii target of rapamycin (TOR), putative 0.0024 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Plasmodium falciparum trophozoite exported protein 1 0.0027 0.0071 0.0071
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0538 0.269 0.269
Schistosoma mansoni serine/threonine protein kinase 0.0018 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0027 0.0071 0.0093
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.0405 0.0405
Echinococcus granulosus peptide allatostatin:somatostatin 0.0093 0.0405 0.0405
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Echinococcus granulosus biogenic amine 5HT receptor 0.0179 0.0847 0.0847
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Trypanosoma brucei C-8 sterol isomerase, putative 0.07 0.3517 0.3517
Schistosoma mansoni neuropeptide f receptor 76f 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0018 0.0024 0.0024
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0027 0.0071 0.0071
Brugia malayi vesicular acetylcholine transporter unc-17 0.0161 0.0757 0.0757
Echinococcus granulosus casein kinase ii subunit alpha 0.1965 1 1
Leishmania major protein kinase, putative 0.0022 0.0046 0.0046
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0538 0.269 0.269
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0027 0.0071 0.0071
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0093 0.0405 0.0405
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Echinococcus multilocularis G-protein coupled receptor, putative 0.0093 0.0405 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0027 0.0071 0.0093
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Mycobacterium leprae PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE L PKNL (PROTEIN KINASE L) (STPK L) 0.0013 0 0.5
Trypanosoma brucei predicted zinc finger protein 0.0027 0.0071 0.0071
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0027 0.0071 0.0071
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.0405 0.0405
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0538 0.269 0.269
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1514 0.7686 0.7686
Echinococcus granulosus cell growth regulator with ring finger domain 0.0027 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.1514 0.7686 0.7686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0093 0.0405 0.0405
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Brugia malayi Dopamine receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0132 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Echinococcus multilocularis RING finger protein 185 0.0027 0.0071 0.0071
Schistosoma mansoni cellular tumor antigen P53 0.026 0.1263 0.1263
Echinococcus granulosus SWI:SNF matrix associated 0.1514 0.7686 0.7686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Echinococcus granulosus vesicular acetylcholine transporter 0.0161 0.0757 0.0757
Brugia malayi Neuralized family protein 0.0027 0.0071 0.0071
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0161 0.0757 0.0985
Echinococcus multilocularis orexin receptor type 2 0.0093 0.0405 0.0405
Trypanosoma brucei hypothetical protein, conserved 0.0538 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0358 0.1764 0.1764
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0027 0.0071 0.0071
Plasmodium falciparum casein kinase 2, alpha subunit 0.1965 1 1
Echinococcus multilocularis serotonin receptor 0.0179 0.0847 0.0847
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Toxoplasma gondii hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus neuropeptide Y receptor 0.0093 0.0405 0.0405
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0179 0.0847 0.0847
Brugia malayi putative neuropeptide receptor NPR1 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Brugia malayi Serotonin receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0061 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Echinococcus multilocularis casein kinase ii subunit alpha 0.1965 1 1
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0116 0.0523 0.0523
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0046 0.0046
Echinococcus granulosus g protein coupled receptor 0.0093 0.0405 0.0405
Schistosoma mansoni biogenic amine receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0093 0.0405 0.0527
Schistosoma mansoni amine GPCR 0.0093 0.0405 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0071 0.0071
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Leishmania major protein kinase, putative 0.0027 0.007 0.007
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.004 0.004
Echinococcus multilocularis dro:myosuppressin receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus G protein coupled receptor 139 0.0093 0.0405 0.0405
Schistosoma mansoni opsin-like receptor 0.0093 0.0405 0.0405
Plasmodium falciparum cGMP-dependent protein kinase 0.0018 0.0024 0.0024
Giardia lamblia Kinase, CMGC CK2 0.1965 1 1
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Echinococcus multilocularis neuropeptide receptor 0.0093 0.0405 0.0405
Giardia lamblia Zinc finger domain 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Schistosoma mansoni fusion 0.0538 0.269 0.269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0061 0.0061
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0032 0.0094 0.0094
Toxoplasma gondii CMGC kinase, CK2 family 0.1965 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.041 0.2034 0.2034
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0027 0.0071 0.0071
Brugia malayi G protein-coupled receptor 0.0093 0.0405 0.0405
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0062
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0538 0.269 0.3499
Brugia malayi PAS domain containing protein 0.0034 0.0108 0.0108
Loa Loa (eye worm) G-protein coupled receptor 0.0093 0.0405 0.0405
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.124 0.124
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1514 0.7686 0.7686
Schistosoma mansoni zinc finger protein 0.0027 0.0071 0.0071
Brugia malayi hypothetical protein 0.0027 0.0071 0.0071
Echinococcus multilocularis neuropeptide receptor A26 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0538 0.269 0.269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Brugia malayi G-protein coupled receptor 0.0093 0.0405 0.0405
Echinococcus granulosus ring finger protein 113a 0.0027 0.0071 0.0071
Mycobacterium ulcerans putative regulatory protein 0.0026 0.0062 1
Echinococcus multilocularis g-protein coupled receptor 0.0093 0.0405 0.0405
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi ERG2 and Sigma1 receptor like protein 0.07 0.3517 0.3517
Schistosoma mansoni TRABID protein (C64 family) 0.0538 0.269 0.269
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0538 0.269 0.269
Onchocerca volvulus 0.0093 0.0405 0.0527
Brugia malayi bHLH-PAS transcription factor 0.0026 0.0062 0.0062
Onchocerca volvulus 0.0093 0.0405 0.0527
Trichomonas vaginalis ankyrin, putative 0.0027 0.0071 0.0071
Schistosoma mansoni ring finger protein 151 0.0027 0.0071 0.0071
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0538 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.07 0.3517 0.3517
Trypanosoma cruzi hypothetical protein 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0538 0.269 0.269
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Entamoeba histolytica SPRY domain protein 0.0027 0.0071 0.0071
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0027 0.0071 0.0071
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1514 0.7686 0.7686
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0071 0.0071
Echinococcus granulosus neuropeptides capa receptor 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Plasmodium falciparum zinc finger protein, putative 0.0027 0.0071 0.0071
Echinococcus multilocularis vesicular acetylcholine transporter 0.0161 0.0757 0.0757
Echinococcus multilocularis allatostatin A receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Schistosoma mansoni opsin-like receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Echinococcus multilocularis SWI:SNF matrix associated 0.1514 0.7686 0.7686
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0032 0.0094 0.0094
Echinococcus multilocularis tumor protein p63 0.1776 0.903 0.903
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni neuropeptide receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis neuropeptide Y receptor 0.0093 0.0405 0.0405
Schistosoma mansoni zinc finger protein 0.0538 0.269 0.269
Echinococcus multilocularis G protein coupled receptor 139 0.0093 0.0405 0.0405
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0037 0.0037
Echinococcus granulosus somatostatin receptor 0.0093 0.0405 0.0405
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0013 0 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Echinococcus granulosus single minded 2 0.0029 0.0079 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Trypanosoma cruzi casein kinase II, putative 0.1965 1 1
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0027 0.0071 0.0071
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0574 0.2874 0.2874
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H) 0.0013 0 0.5
Brugia malayi brahma associated protein 60 kDa 0.1514 0.7686 0.7686
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Onchocerca volvulus 0.026 0.1263 0.1643
Trypanosoma cruzi target of rapamycin kinase 3 0.0025 0.0061 0.0061
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0093 0.0405 0.0405
Trypanosoma cruzi WLM domain containing protein, putative 0.0538 0.269 0.269
Schistosoma mansoni aryl hydrocarbon receptor 0.0034 0.0108 0.0108
Leishmania major hypothetical protein, unknown function 0.0027 0.0071 0.0071
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0093 0.0405 0.0405
Echinococcus granulosus cGMP dependent protein kinase 1 0.0018 0.0024 0.0024
Schistosoma mansoni vesicular acetylcholine transporter 0.0161 0.0757 0.0757
Mycobacterium tuberculosis Anchored-membrane serine/threonine-protein kinase PknF (protein kinase F) (STPK F) 0.0013 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0093 0.0405 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0027 0.0071 0.0071
Entamoeba histolytica protein kinase domain containing protein 0.1965 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0022 0.0046 0.0046
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0032 0.0094 0.0094
Toxoplasma gondii helicase, putative 0.0027 0.0071 0.0071
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0032 0.0094 0.0094
Schistosoma mansoni adenoreceptor 0.0093 0.0405 0.0405
Brugia malayi Tachykinin-like peptides receptor 99D 0.0093 0.0405 0.0405
Leishmania major C-8 sterol isomerase-like protein 0.07 0.3517 0.3517
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi Serotonin receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0093 0.0405 0.0405
Echinococcus multilocularis calcium activated potassium channel 0.0016 0.0012 0.0012
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0538 0.269 0.269
Schistosoma mansoni amine GPCR 0.0093 0.0405 0.0405
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0093 0.0405 0.0405
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0032 0.0094 0.0094
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0027 0.0071 0.0071
Onchocerca volvulus RING finger protein 141 homolog 0.0027 0.0071 0.0093
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Schistosoma mansoni neuropeptide F-like receptor 0.0093 0.0405 0.0405
Echinococcus granulosus cGMP dependent protein kinase 1 0.0018 0.0024 0.0024
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0538 0.269 0.269
Loa Loa (eye worm) AGC/PKG protein kinase 0.0018 0.0024 0.0024
Schistosoma mansoni neuropeptide receptor 0.0093 0.0405 0.0405
Brugia malayi hypothetical protein 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Toxoplasma gondii hypothetical protein 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0093 0.0405 0.0405
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B) 0.0013 0 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Onchocerca volvulus Protein neuralized homolog 0.0027 0.0071 0.0093
Giardia lamblia Kinase 0.0041 0.014 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Schistosoma mansoni hypothetical protein 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi hypothetical protein 0.0025 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Giardia lamblia Ribonuclease 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus neuropeptide receptor 0.0093 0.0405 0.0405
Schistosoma mansoni biogenic amine receptor 0.0093 0.0405 0.0405
Schistosoma mansoni growth hormone secretagogue receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Chlamydia trachomatis DNA topoisomerase I 0.1514 0.7686 1
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Echinococcus multilocularis neuropeptide receptor 0.0093 0.0405 0.0405
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Entamoeba histolytica casein kinase, putative 0.1965 1 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0538 0.269 0.269
Echinococcus granulosus g protein coupled receptor 0.0093 0.0405 0.0405
Brugia malayi sulfakinin receptor protein 0.041 0.2034 0.2034
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Schistosoma mansoni hypothetical protein 0.0093 0.0405 0.0405
Onchocerca volvulus Neuropeptide F receptor homolog 0.0093 0.0405 0.0527
Brugia malayi YY1-associated factor 2 0.0538 0.269 0.269
Brugia malayi Cytochrome P450 family protein 0.0022 0.0045 0.0045
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.1965 1 1
Schistosoma mansoni amine GPCR 0.0093 0.0405 0.0405
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0027 0.0071 0.0071
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0093 0.0405 0.0405
Schistosoma mansoni biogenic amine (5HT) receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis neuropeptides capa receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0027 0.0071 0.0071
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0027 0.0071 0.0071
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0027 0.0071 0.0071
Mycobacterium tuberculosis Probable transmembrane serine/threonine-protein kinase E PknE (protein kinase E) (STPK E) 0.0013 0 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0538 0.269 0.269
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni peter pan-related 0.0027 0.0071 0.0071
Leishmania major protein kinase, putative 0.0018 0.0024 0.0024
Echinococcus granulosus allatostatin A receptor 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Brugia malayi RING zinc finger protein 0.0027 0.0071 0.0071
Mycobacterium tuberculosis Serine/threonine-protein kinase transcriptional regulatory protein PknK (protein kinase K) (STPK K) 0.0013 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0115 0.0115
Schistosoma mansoni rnf5 0.0027 0.0071 0.0071
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0093 0.0405 0.0405
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0093 0.0405 0.0405
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0022 0.0046 0.0046
Onchocerca volvulus 0.0093 0.0405 0.0527
Schistosoma mansoni transcription factor LCR-F1 0.0025 0.0062 0.0062
Onchocerca volvulus 0.0093 0.0405 0.0527
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Echinococcus granulosus neuropeptide receptor 0.0093 0.0405 0.0405
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0093 0.0405 0.0405
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0538 0.269 0.3499
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0094 0.0094
Schistosoma mansoni histamine h1 receptor 0.0093 0.0405 0.0405
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0062
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0018 0.0024 0.0024
Brugia malayi brahma associated protein 60 kDa 0.1514 0.7686 0.7686
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Leishmania major DNA repair protein-like protein 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Brugia malayi hypothetical protein 0.041 0.2034 0.2034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0091 0.0091
Echinococcus multilocularis g protein coupled receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis 0.0027 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.0027 0.0071 0.0071
Schistosoma mansoni hypothetical protein 0.1514 0.7686 0.7686
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0027 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0052 0.0052
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Leishmania major hypothetical protein, conserved 0.0538 0.269 0.269
Schistosoma mansoni brg-1 associated factor 0.1514 0.7686 0.7686
Echinococcus multilocularis transfer RNA-Lys 0.0026 0.0062 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0538 0.269 0.269
Brugia malayi hypothetical protein 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0093 0.0405 0.0527
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.1965 1 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0093 0.0405 0.0405
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0027 0.0071 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0538 0.269 0.269
Schistosoma mansoni hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus 7TM GPCR rhodopsin 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Brugia malayi hypothetical protein 0.0093 0.0405 0.0405
Trypanosoma brucei ring finger containing protein 0.0027 0.0071 0.0071
Echinococcus granulosus tm gpcr rhodopsin 0.0093 0.0405 0.0405
Echinococcus multilocularis sex peptide receptor 0.0093 0.0405 0.0405
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) RiNg Finger protein family member 0.0027 0.0071 0.0071
Giardia lamblia Kinase, NEK 0.0041 0.014 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Mycobacterium leprae Probable transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) 0.0013 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0027 0.0071 0.0093
Schistosoma mansoni biogenic amine receptor 0.0093 0.0405 0.0405
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0071 0.0071
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Trichomonas vaginalis ion channel nompc, putative 0.0027 0.0071 0.0071
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0093 0.0405 0.0405
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1514 0.7686 0.7686
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0061 0.0061
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0032 0.0094 0.0094
Echinococcus multilocularis neuropeptides capa receptor 0.0093 0.0405 0.0405
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0071
Onchocerca volvulus Putative RING finger protein 207 0.0027 0.0071 0.0093
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus multilocularis zinc finger protein Ran binding 0.0538 0.269 0.269
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0025 0.0062 0.0062
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Echinococcus granulosus neuropeptide FF receptor 2 0.0093 0.0405 0.0405
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0027 0.0071 0.0071
Echinococcus granulosus serotonin receptor 0.0093 0.0405 0.0405
Schistosoma mansoni neuropeptide receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis CMGC family protein kinase 0.1965 1 1
Trichomonas vaginalis ankyrin, putative 0.0027 0.0071 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Echinococcus multilocularis fmrfamide receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Loa Loa (eye worm) RING finger protein 20 0.0027 0.0071 0.0071
Onchocerca volvulus 0.0026 0.0062 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Mycobacterium tuberculosis Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A) 0.0013 0 0.5
Trypanosoma cruzi C-8 sterol isomerase, putative 0.07 0.3517 0.3517
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0071
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Schistosoma mansoni opsin-like receptor 0.0093 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Echinococcus granulosus g protein coupled receptor 0.0093 0.0405 0.0405
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1514 0.7686 0.7686
Leishmania major hypothetical protein, conserved 0.0538 0.269 0.269
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Echinococcus granulosus 7tm_1 domain containing protein 0.0093 0.0405 0.0405
Onchocerca volvulus 0.1514 0.7686 1
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0032 0.0094 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0094 0.0094
Schistosoma mansoni neuropeptide F-like receptor 0.0093 0.0405 0.0405
Brugia malayi ORL1-like opioid receptor 0.0093 0.0405 0.0405
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0027 0.0071 0.0071
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0027 0.0071 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0071 0.0071
Brugia malayi Zinc finger protein 183 homolog 0.0027 0.0071 0.0071
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Giardia lamblia Hypothetical protein 0.0027 0.0071 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0094 0.0094
Schistosoma mansoni RNA binding protein 0.0538 0.269 0.269
Echinococcus granulosus rhodopsin orphan GPCR 0.0093 0.0405 0.0405
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0032 0.0094 0.0094
Loa Loa (eye worm) melatonin receptor type 1A 0.0093 0.0405 0.0405
Giardia lamblia Protein 21.1 0.0027 0.0071 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0025 0.0061 0.0061
Brugia malayi Dopamine receptor protein 1 0.0093 0.0405 0.0405
Onchocerca volvulus 0.0093 0.0405 0.0527
Onchocerca volvulus 0.0093 0.0405 0.0527
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0538 0.269 0.269
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0093 0.0405 0.0405
Giardia lamblia Zinc finger domain 0.0027 0.0071 0.0071
Plasmodium vivax hypothetical protein, conserved 0.1514 0.7686 0.7686
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0093 0.0405 0.0405
Echinococcus granulosus neuropeptides capa receptor 0.0093 0.0405 0.0405
Echinococcus granulosus calcium activated potassium channel 0.0016 0.0012 0.0012
Onchocerca volvulus 0.0538 0.269 0.3499
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0071 0.0071
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0093 0.0405 0.0405
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0061 0.0061

Activities

Activity type Activity value Assay description Source Reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
GI50 (functional) -4 PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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