Detailed information for compound 1743798

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 283.408 | Formula: C19H25NO
  • H donors: 1 H acceptors: 1 LogP: 4.16 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCCCN1CC[C@]2([C@H](C1Cc1c2cc(cc1)O)C)C
  • InChi: 1S/C19H25NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h1,7-8,13-14,18,21H,5-6,9-12H2,2-3H3/t14-,18?,19-/m0/s1
  • InChiKey: QLVSIRINICYAHG-CJESRSHOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Mus musculus opioid receptor, mu 1 Starlite/ChEMBL References
Mus musculus opioid receptor, delta 1 Starlite/ChEMBL References
Mus musculus sigma non-opioid intracellular receptor 1 Starlite/ChEMBL References
Mus musculus opioid receptor, kappa 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma brucei gambiense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma brucei C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania infantum C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania donovani C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania braziliensis C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Candida albicans sterol C8-C7 isomerase Get druggable targets OG5_131051 All targets in OG5_131051
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma congolense C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
Brugia malayi ERG2 and Sigma1 receptor like protein Get druggable targets OG5_131051 All targets in OG5_131051
Trypanosoma cruzi C-8 sterol isomerase, putative Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania mexicana C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131051 All targets in OG5_131051
Leishmania major C-8 sterol isomerase-like protein Get druggable targets OG5_131051 All targets in OG5_131051
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi hypothetical protein opioid receptor, kappa 1 380 aa 323 aa 20.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0031 0.0012 0.0083
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Echinococcus granulosus insulin receptor 0.0199 0.0371 0.0371
Echinococcus granulosus serine threonine protein kinase nrc 0.003 0.0011 0.0011
Trypanosoma brucei cdc2-related kinase 1 0.0053 0.0059 0.0299
Echinococcus granulosus histone deacetylase 0.0134 0.0232 0.0232
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0067 0.0089 0.0089
Brugia malayi Melatonin receptor type 1A 0.0072 0.01 0.01
Trichomonas vaginalis cyclin D, putative 0.0032 0.0015 0.0155
Schistosoma mansoni tyrosine kinase 0.0141 0.0248 0.0248
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0012 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Loa Loa (eye worm) acetylcholine receptor protein 0.0031 0.0012 0.0009
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0012 0.0012
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Echinococcus granulosus cyclin dependent kinase 1 0.0053 0.0059 0.0059
Echinococcus multilocularis histone deacetylase 7 0.0134 0.0232 0.0232
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.007 0.0738
Brugia malayi Dopamine receptor protein 2 0.0072 0.01 0.01
Trypanosoma cruzi cyclin 6, putative 0.0076 0.0109 0.0573
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.018 0.033 0.033
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0036 0.0023 0.0023
Schistosoma mansoni pyruvate dehydrogenase 0.0122 0.0207 0.0207
Schistosoma mansoni histamine h1 receptor 0.0072 0.01 0.01
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.0059 0.0625
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0028 0.0007 0.0007
Trypanosoma brucei histone deacetylase 1 0.0468 0.0946 0.5118
Echinococcus multilocularis RNA directed DNA polymerase 0.004 0.0033 0.0033
Entamoeba histolytica protein kinase, putative 0.0302 0.0591 0.6248
Echinococcus multilocularis tyrosine protein kinase Blk 0.0039 0.003 0.003
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0302 0.0591 0.6248
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0072 0.01 0.01
Schistosoma mansoni histone deacetylase 1 2 3 0.0134 0.0232 0.0232
Onchocerca volvulus 0.0072 0.01 0.0989
Onchocerca volvulus 0.0072 0.01 0.0989
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0058 0.007 0.0698
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Onchocerca volvulus 0.0072 0.01 0.0989
Brugia malayi Histone deacetylase family protein 0.0134 0.0232 0.0232
Loa Loa (eye worm) cyclin domain-containing protein 0.0032 0.0015 0.0012
Onchocerca volvulus 0.0031 0.0012 0.0083
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.003 0.0011 0.007
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0031 0.0012 0.0012
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis mitogen activated protein kinase 14 0.0137 0.024 0.024
Echinococcus multilocularis neuropeptide FF receptor 2 0.0072 0.01 0.01
Echinococcus granulosus defective proboscis extension response 0.0037 0.0026 0.0026
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.0059 0.0299
Onchocerca volvulus 0.0072 0.01 0.0989
Entamoeba histolytica protein kinase, putative 0.0049 0.0052 0.0547
Echinococcus granulosus NCK adaptor protein 0.0039 0.003 0.003
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.0059 0.0059
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0058 0.007 0.007
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0072 0.01 0.0989
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0072 0.01 0.01
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0109 0.0109
Trypanosoma brucei C-8 sterol isomerase, putative 0.0889 0.1844 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus g protein coupled receptor 0.0072 0.01 0.01
Brugia malayi G protein-coupled receptor 0.0072 0.01 0.01
Echinococcus granulosus NDR protein kinase 0.0028 0.0007 0.0007
Leishmania major protein kinase A catalytic subunit isoform 1 0.005 0.0053 0.0265
Echinococcus granulosus glycine receptor subunit beta 0.0067 0.0089 0.0089
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0039 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0036 0.0023 0.0023
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.003 0.0011 0.0011
Brugia malayi serine/threonine-protein kinase PAK 7 0.0196 0.0364 0.0364
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Leishmania major histone deacetylase, putative 0.0468 0.0946 0.5118
Echinococcus granulosus histone deacetylase 7 0.0134 0.0232 0.0232
Echinococcus multilocularis g-protein coupled receptor 0.0072 0.01 0.01
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Echinococcus granulosus g protein coupled receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0072 0.01 0.01
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis cyclins, putative 0.0052 0.0058 0.0613
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus multilocularis g protein coupled receptor 0.0072 0.01 0.01
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0031 0.0012 0.0012
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0039 0.003 0.003
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0105 0.0171 0.0171
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0141 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Toxoplasma gondii histone deacetylase HDAC4 0.0134 0.0232 0.2418
Echinococcus granulosus 7TM GPCR rhodopsin 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0113 0.0187 0.0187
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Echinococcus multilocularis G protein coupled receptor 139 0.0072 0.01 0.01
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Giardia lamblia Kinase, PLK 0.0105 0.0171 0.1813
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0057 0.0606
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni protein kinase 0.0027 0.0004 0.0004
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0057 0.0068 0.0068
Brugia malayi histone deacetylase 1 (HD1) 0.0468 0.0946 0.0946
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.003 0.0011 0.0011
Echinococcus granulosus Protein kinase C brain isozyme 0.0076 0.0109 0.0109
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0059 0.0625
Echinococcus multilocularis orexin receptor type 2 0.0072 0.01 0.01
Echinococcus granulosus protein kinase C gamma type 0.007 0.0096 0.0096
Onchocerca volvulus 0.0067 0.0089 0.0877
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Brugia malayi ORL1-like opioid receptor 0.0072 0.01 0.01
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Echinococcus multilocularis glycine receptor subunit beta 0.0067 0.0089 0.0089
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Toxoplasma gondii AGC kinase 0.005 0.0053 0.0518
Trypanosoma cruzi cdc2-related kinase 1 0.0053 0.0059 0.0299
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0072 0.01 0.01
Echinococcus granulosus N chimaerin 0.0027 0.0005 0.0005
Brugia malayi RE15519p 0.0072 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0199 0.0371 0.0371
Echinococcus multilocularis activin receptor type 0.0027 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Trypanosoma brucei cdc2-related kinase 3 0.0053 0.0059 0.0299
Loa Loa (eye worm) hypothetical protein 0.0602 0.1231 0.1229
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0583 0.119 0.119
Echinococcus multilocularis insulin receptor 0.0199 0.0371 0.0371
Brugia malayi serine/threonine-protein kinase plk-2 0.0105 0.0171 0.0171
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Loa Loa (eye worm) histone deacetylase 0.0134 0.0232 0.0229
Echinococcus granulosus protein kinase shaggy 0.0058 0.007 0.007
Brugia malayi sulfakinin receptor protein 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis mitogen activated protein kinase 3 0.0061 0.0076 0.0076
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Schistosoma mansoni cell adhesion molecule 0.0044 0.0041 0.0041
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0468 0.0946 0.0943
Loa Loa (eye worm) melatonin receptor type 1A 0.0072 0.01 0.0097
Entamoeba histolytica protein kinase domain containing protein 0.0302 0.0591 0.6248
Onchocerca volvulus 0.0076 0.0109 0.1088
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0037 0.0026 0.0026
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0049 0.0052 0.0049
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Echinococcus granulosus 7tm_1 domain containing protein 0.0072 0.01 0.01
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0057 0.0068 0.0068
Echinococcus granulosus serotonin receptor 0.0072 0.01 0.01
Echinococcus granulosus serine/threonine protein kinase 0.0032 0.0015 0.0015
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0072 0.01 0.01
Toxoplasma gondii histone deacetylase HDAC3 0.0468 0.0946 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptide s receptor 0.0072 0.01 0.01
Trypanosoma brucei polo-like protein kinase 0.0105 0.0171 0.091
Echinococcus granulosus epidermal growth factor receptor 0.0159 0.0286 0.0286
Trypanosoma cruzi rac serine-threonine kinase, putative 0.003 0.0011 0.0036
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0196 0.0364 0.0361
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.005 0.0053 0.0265
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0057 0.0068 0.0068
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0072 0.01 0.01
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Schistosoma mansoni opsin-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0037
Echinococcus multilocularis serine:threonine protein kinase N2 0.0028 0.0007 0.0007
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Echinococcus granulosus hemicentin 1 0.0038 0.0028 0.0028
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0044 0.0041 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0171 0.0171
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.0089 0.0944
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0119 0.02 0.02
Onchocerca volvulus 0.0036 0.0023 0.0198
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis tyrosine kinase 0.0039 0.003 0.003
Plasmodium falciparum glycogen synthase kinase 3 0.0058 0.007 0.0698
Onchocerca volvulus 0.0072 0.01 0.0989
Brugia malayi Serotonin receptor 0.0072 0.01 0.01
Echinococcus multilocularis 0.0065 0.0085 0.0085
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0171 0.091
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Schistosoma mansoni neurotransmitter gated ion channel 0.0031 0.0012 0.0012
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0889 0.1844 0.1844
Echinococcus granulosus twitchin 0.0055 0.0064 0.0064
Echinococcus multilocularis protein kinase c epsilon type 0.0036 0.0023 0.0023
Onchocerca volvulus 0.0031 0.0013 0.0088
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.0059 0.0299
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0043 0.0038 0.0356
Echinococcus multilocularis serine threonine protein kinase 0.0113 0.0187 0.0187
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0059 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Trypanosoma brucei histone deacetylase 4 0.0134 0.0232 0.1238
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0053 0.0053
Trypanosoma cruzi CYC2-like cyclin, putative 0.0076 0.0109 0.0573
Giardia lamblia Kinase, AGC PKA 0.005 0.0053 0.0559
Entamoeba histolytica cyclin family protein 0.0032 0.0015 0.0155
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0029 0.0029
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Leishmania major histone deacetylase, putative 0.0468 0.0946 0.5118
Schistosoma mansoni nck2/grb4 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0067 0.0089 0.0089
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0031 0.0012 0.0012
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0232 0.0232
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0302 0.0591 0.6248
Echinococcus granulosus fmrfamide receptor 0.0072 0.01 0.01
Entamoeba histolytica histone deacetylase, putative 0.0468 0.0946 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0199 0.0371 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0089 0.0089
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0058 0.007 0.0067
Schistosoma mansoni tyrosine kinase 0.0159 0.0286 0.0286
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0007 0.0074
Toxoplasma gondii AGC kinase 0.005 0.0053 0.0518
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Brugia malayi follicle stimulating hormone receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0099 0.0157 0.0154
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) AGC/NDR protein kinase 0.0028 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) AUR protein kinase 0.0302 0.0591 0.0588
Loa Loa (eye worm) hypothetical protein 0.0889 0.1844 0.1841
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0027 0.0005 0.0005
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0029 0.001 0.001
Echinococcus granulosus tyrosine kinase 0.0039 0.003 0.003
Loa Loa (eye worm) TK/ABL protein kinase 0.025 0.048 0.0477
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Brugia malayi GnHR receptor homolog 0.0072 0.01 0.01
Brugia malayi SRC-1 0.0057 0.0068 0.0068
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Loa Loa (eye worm) AGC/PKA protein kinase 0.005 0.0053 0.005
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) hypothetical protein 0.0134 0.0232 0.0229
Schistosoma mansoni histone deacetylase 4 5 0.0134 0.0232 0.0232
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0072 0.01 0.0097
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0072 0.01 0.0097
Echinococcus granulosus protein kinase c epsilon type 0.0036 0.0023 0.0023
Brugia malayi Tyrosine-protein kinase abl-1 0.013 0.0225 0.0225
Plasmodium vivax histone deacetylase 2, putative 0.0134 0.0232 0.2364
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0072 0.01 0.01
Schistosoma mansoni biogenic amine receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0076 0.0109 0.0573
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0032 0.0015 0.006
Echinococcus granulosus nAChR subunit 0.0067 0.0089 0.0089
Entamoeba histolytica protein kinase, putative 0.0027 0.0004 0.0047
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0072 0.01 0.01
Echinococcus granulosus serine:threonine protein kinase N2 0.0028 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis cyclin dependent kinase 5 0.0053 0.0059 0.0059
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Entamoeba histolytica SH2-protein kinase domain containing protein 0.003 0.0011 0.0115
Loa Loa (eye worm) hypothetical protein 0.0039 0.003 0.0027
Echinococcus multilocularis histone deacetylase 1 0.0468 0.0946 0.0946
Loa Loa (eye worm) AGC/PKN protein kinase 0.0028 0.0007 0.0004
Echinococcus granulosus g protein coupled receptor 0.0072 0.01 0.01
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0028 0.0007 0.0004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.004 0.0033 0.003
Onchocerca volvulus Serine\/threonine kinase homolog 0.0105 0.0171 0.173
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Brugia malayi neuropeptide F receptor 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptide receptor 0.0072 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0141 0.0248 0.0248
Echinococcus granulosus histone deacetylase 3 0.0468 0.0946 0.0946
Brugia malayi Protein kinase c protein 2 0.0057 0.0068 0.0068
Plasmodium vivax glycogen synthase kinase 3, putative 0.0058 0.007 0.0632
Echinococcus granulosus neuropeptide FF receptor 2 0.0072 0.01 0.01
Echinococcus multilocularis histone deacetylase 3 0.0468 0.0946 0.0946
Loa Loa (eye worm) hypothetical protein 0.0076 0.0109 0.0106
Trypanosoma brucei protein kinase, putative 0.0061 0.0076 0.0392
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trypanosoma brucei histone deacetylase 3 0.0134 0.0232 0.1238
Loa Loa (eye worm) CDC7 protein kinase 0.0067 0.0089 0.0086
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Echinococcus granulosus nAChR subunit 0.0036 0.0023 0.0023
Trichomonas vaginalis AGC family protein kinase 0.005 0.0053 0.0559
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0028 0.0007 0.0007
Schistosoma mansoni growth factor receptor-bound protein 0.0039 0.003 0.003
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0053 0.0059 0.0059
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis epidermal growth factor receptor 0.0159 0.0286 0.0286
Brugia malayi Fibronectin type III domain containing protein 0.0037 0.0026 0.0026
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0057 0.0068 0.0068
Loa Loa (eye worm) TK/EGFR protein kinase 0.023 0.0436 0.0433
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0005 0.0005
Onchocerca volvulus 0.0067 0.0089 0.0879
Echinococcus granulosus dro:myosuppressin receptor 0.0072 0.01 0.01
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.01 0.01
Echinococcus granulosus biogenic amine 5HT receptor 0.0072 0.01 0.01
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.01 0.01
Echinococcus multilocularis serine:threonine protein kinase 38 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Plasmodium falciparum protein kinase, putative 0.0113 0.0187 0.1946
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.0093 0.0145 0.0145
Leishmania major developmentally regulated phosphoprotein-like protein 0.0122 0.0207 0.1101
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0007 0.0074
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.018 0.033 0.033
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0067 0.0089 0.0089
Schistosoma mansoni biogenic amine receptor 0.0072 0.01 0.01
Giardia lamblia Kinase, CDC7 0.0067 0.0089 0.0944
Toxoplasma gondii histone deacetylase HDAC2 0.0468 0.0946 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0059 0.0625
Plasmodium vivax histone deacetylase, putative 0.0134 0.0232 0.2364
Plasmodium falciparum protein kinase 5 0.0053 0.0059 0.0584
Plasmodium vivax histone deacetylase, putative 0.0134 0.0232 0.2364
Echinococcus multilocularis fmrfamide receptor 0.0072 0.01 0.01
Loa Loa (eye worm) AGC/PKA protein kinase 0.005 0.0053 0.005
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Giardia lamblia Histone deacetylase 0.0468 0.0946 1
Brugia malayi Dopamine receptor protein 1 0.0072 0.01 0.01
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0067 0.0089 0.0089
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0067 0.0089 0.0086
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0109 0.0109
Brugia malayi AKH receptor 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni pyruvate dehydrogenase 0.0115 0.0192 0.0192
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0199 0.0371 0.0371
Trypanosoma cruzi Protein kinase B 0.0032 0.0015 0.006
Schistosoma mansoni growth factor receptor-bound protein 0.0039 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni pyruvate dehydrogenase 0.0115 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Brugia malayi hypothetical protein 0.0037 0.0026 0.0026
Trypanosoma cruzi cyclin, putative 0.0076 0.0109 0.0573
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0015 0.016
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Brugia malayi Protein kinase domain containing protein 0.048 0.097 0.097
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Trypanosoma cruzi cdc2-related kinase 3 0.0053 0.0059 0.0299
Entamoeba histolytica hypothetical protein 0.0036 0.0023 0.0248
Loa Loa (eye worm) hypothetical protein 0.0073 0.0103 0.01
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0053 0.0053
Brugia malayi larval opioid receptor 0.0072 0.01 0.01
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0057 0.0068 0.0068
Brugia malayi Hr1 repeat family protein 0.0028 0.0007 0.0007
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.005 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus granulosus neuropeptide receptor A26 0.0072 0.01 0.01
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0137 0.024 0.1281
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0072 0.01 0.01
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Loa Loa (eye worm) G-protein coupled receptor 0.0072 0.01 0.0097
Echinococcus multilocularis neuroglian 0.0046 0.0045 0.0045
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0067 0.0089 0.0086
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0076 0.0076
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0113 0.0187 0.0184
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0057 0.0068 0.0068
Giardia lamblia G2/mitotic-specific cyclin B 0.0076 0.0109 0.1157
Onchocerca volvulus 0.0036 0.0023 0.0198
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Schistosoma mansoni cyclins 0.0032 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0033 0.0018 0.0018
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Echinococcus granulosus tyrosine protein kinase Blk 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0076 0.0109 0.0106
Echinococcus multilocularis roundabout 2 0.0053 0.0059 0.0059
Echinococcus granulosus cyclin B3 1 0.0032 0.0015 0.0015
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0031 0.0012 0.0009
Echinococcus granulosus tyrosine protein kinase Lyn 0.0066 0.0087 0.0087
Plasmodium falciparum serine/threonine protein kinase, putative 0.0302 0.0591 0.6231
Echinococcus granulosus tyrosine protein kinase Srms 0.0039 0.003 0.003
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.007 0.0738
Giardia lamblia Kinase, CMGC GSK 0.0058 0.007 0.0738
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus tyrosine protein kinase Src42A 0.0057 0.0068 0.0068
Echinococcus multilocularis cyclin B3 1 0.0032 0.0015 0.0015
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0137 0.024 0.1281
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Echinococcus granulosus mitogen activated protein kinase 11 0.0137 0.024 0.024
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0039 0.003 0.0027
Onchocerca volvulus Tyrosine kinase homolog 0.0367 0.0729 0.7502
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.007 0.0738
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0028 0.0007 0.0004
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0193 0.0358 0.0355
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Echinococcus granulosus histone deacetylase 6 0.0134 0.0232 0.0232
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus tyrosine protein kinase ABL1 0.025 0.048 0.048
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Schistosoma mansoni kinase 0.0058 0.007 0.007
Entamoeba histolytica protein kinase domain containing protein 0.0058 0.007 0.0738
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus multilocularis protein kinase shaggy 0.0058 0.007 0.007
Loa Loa (eye worm) TK protein kinase 0.0039 0.003 0.0027
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Brugia malayi Immunoglobulin I-set domain containing protein 0.0127 0.0218 0.0218
Schistosoma mansoni tyrosine kinase 0.0119 0.02 0.02
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0302 0.0591 0.0591
Onchocerca volvulus Netrin receptor homolog 0.0031 0.0013 0.0088
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni alpha-1 adrenergic receptor 0.0072 0.01 0.01
Echinococcus granulosus tyrosine protein kinase Src64B 0.0057 0.0068 0.0068
Brugia malayi Furin-like cysteine rich region family protein 0.023 0.0436 0.0436
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0119 0.02 0.02
Onchocerca volvulus 0.0039 0.003 0.0264
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0053 0.0059 0.0056
Trichomonas vaginalis AGC family protein kinase 0.0028 0.0007 0.0074
Echinococcus multilocularis neuropeptide receptor A26 0.0072 0.01 0.01
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.01 0.01
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0067 0.0089 0.0089
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0059 0.0625
Loa Loa (eye worm) hypothetical protein 0.0075 0.0107 0.0104
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0028 0.0007 0.0007
Echinococcus granulosus histone deacetylase 1 0.0468 0.0946 0.0946
Brugia malayi Cyclin, N-terminal domain containing protein 0.0032 0.0015 0.0015
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Echinococcus granulosus tyrosine protein kinase shark 0.0256 0.0493 0.0493
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0039 0.003 0.0027
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0072 0.01 0.01
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0072 0.01 0.01
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Schistosoma mansoni tyrosine kinase 0.0235 0.0448 0.0448
Schistosoma mansoni protein kinase 0.0027 0.0004 0.0004
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus granulosus protein kinase c iota type 0.0034 0.002 0.002
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0061 0.0076 0.0392
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0043 0.0038 0.0182
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Brugia malayi kinase, mitochondrial precursor 0.0122 0.0207 0.0207
Onchocerca volvulus 0.0067 0.0089 0.0877
Echinococcus multilocularis tyrosine protein kinase Srms 0.0039 0.003 0.003
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0039 0.003 0.0027
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.005 0.0053 0.0451
Schistosoma mansoni serine/threonine kinase 0.0028 0.0007 0.0007
Brugia malayi Sex muscle abnormal protein 5 0.0039 0.003 0.003
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0072 0.01 0.01
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0031 0.0012 0.0012
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0057 0.0068 0.0068
Brugia malayi MAP kinase sur-1 0.0061 0.0076 0.0076
Echinococcus granulosus fibroblast growth factor receptor 4 0.0119 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Onchocerca volvulus 0.0072 0.01 0.0989
Schistosoma mansoni tyrosine kinase 0.0199 0.0371 0.0371
Echinococcus multilocularis NCK adaptor protein 0.0039 0.003 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0067 0.0089 0.0086
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Trichomonas vaginalis STE family protein kinase 0.0113 0.0187 0.1981
Brugia malayi protein kinase C II. 0.0036 0.0023 0.0023
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0067 0.0089 0.0089
Echinococcus multilocularis tyrosine protein kinase Abl 0.0138 0.024 0.024
Echinococcus granulosus somatostatin receptor 0.0072 0.01 0.01
Trypanosoma brucei developmentally regulated phosphoprotein 0.0122 0.0207 0.1101
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0024 0.0249
Echinococcus granulosus sex peptide receptor 0.0072 0.01 0.01
Loa Loa (eye worm) IKK protein kinase 0.048 0.097 0.0967
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0072 0.01 0.0097
Echinococcus multilocularis histone deacetylase 0.0134 0.0232 0.0232
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0232 0.0232
Echinococcus granulosus tyrosine kinase 0.0039 0.003 0.003
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0067 0.0089 0.0086
Entamoeba histolytica cyclin family protein 0.0032 0.0015 0.0155
Echinococcus granulosus peptide allatostatin:somatostatin 0.0072 0.01 0.01
Onchocerca volvulus 0.0058 0.007 0.0677
Entamoeba histolytica protein kinase, putative 0.0028 0.0007 0.0074
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0061 0.0076 0.0765
Echinococcus granulosus mitogen activated protein kinase 3 0.0061 0.0076 0.0076
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.005 0.0053 0.0518
Brugia malayi hypothetical protein 0.0029 0.001 0.001
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0027 0.0004 0.0004
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0067 0.0089 0.0086
Entamoeba histolytica protein kinase, putative 0.0058 0.007 0.0738
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0072 0.01 0.0097
Onchocerca volvulus Histone deacetylase 10 homolog 0.0134 0.0232 0.2354
Onchocerca volvulus 0.048 0.097 1
Brugia malayi Protein kinase domain containing protein 0.0091 0.0141 0.0141
Echinococcus multilocularis N chimaerin 0.0027 0.0005 0.0005
Brugia malayi cell division control protein 2 homolog 0.0053 0.0059 0.0059
Schistosoma mansoni vav2 0.0029 0.0009 0.0009
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0036 0.0023 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis dro:myosuppressin receptor 0.0072 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0028 0.0007 0.0007
Echinococcus granulosus alpha 1A adrenergic receptor 0.0072 0.01 0.01
Trypanosoma brucei rac serine-threonine kinase, putative 0.0051 0.0056 0.0284
Schistosoma mansoni nephrin 0.0046 0.0045 0.0045
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.0059 0.0056
Echinococcus multilocularis cyclin dependent kinase 1 0.0053 0.0059 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0067 0.0712
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0193 0.0358 0.0358
Schistosoma mansoni opsin-like receptor 0.0072 0.01 0.01
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0024 0.0249
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0061 0.0076 0.0392
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0105 0.0171 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0031 0.0012 0.0012
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0036 0.0023 0.0023
Echinococcus multilocularis histone deacetylase 6 0.0134 0.0232 0.0232
Onchocerca volvulus 0.0031 0.0013 0.0088
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Toxoplasma gondii histone deacetylase HDAC1 0.0134 0.0232 0.2418
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Echinococcus granulosus histone deacetylase 6 0.0134 0.0232 0.0232
Leishmania major histone deacetylase, putative 0.0134 0.0232 0.1238
Loa Loa (eye worm) AUR protein kinase 0.0302 0.0591 0.0588
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.005 0.0053 0.0265
Schistosoma mansoni neuropeptide F-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.018 0.033 0.0327
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Entamoeba histolytica p21-activated kinase 0.0027 0.0004 0.0047
Echinococcus granulosus roundabout 2 0.0053 0.0059 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Brugia malayi SH2 domain containing protein 0.0039 0.003 0.003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0602 0.1231 0.1231
Echinococcus granulosus tachykinin peptides receptor 99D 0.0072 0.01 0.01
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0036 0.0023 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0072 0.01 0.01
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0037 0.0037
Brugia malayi Serotonin receptor 0.0072 0.01 0.01
Brugia malayi Variant SH3 domain containing protein 0.0039 0.003 0.003
Brugia malayi RhoGAP domain containing protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) TK/KIN16 protein kinase 0.038 0.0757 0.0754
Plasmodium falciparum histone deacetylase 2 0.0134 0.0232 0.2418
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Brugia malayi serine/threonine protein kinase 6 0.0302 0.0591 0.0591
Schistosoma mansoni histone deacetylase hda2 0.0134 0.0232 0.0232
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Entamoeba histolytica protein kinase, putative 0.003 0.0011 0.0115
Echinococcus granulosus contactin 0.0038 0.0028 0.0028
Echinococcus granulosus biogenic amine 5HT receptor 0.0602 0.1231 0.1231
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0061 0.0076 0.0392
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0027 0.0004 0.0004
Schistosoma mansoni titin 0.0038 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.005 0.0053 0.005
Schistosoma mansoni nAChR subunit 0.0031 0.0012 0.0012
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0067 0.0089 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Trichomonas vaginalis cyclin B3, putative 0.0032 0.0015 0.0155
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis AGC family protein kinase 0.0302 0.0591 0.6248
Loa Loa (eye worm) LGC-31 protein 0.0067 0.0089 0.0086
Brugia malayi SH2 domain containing protein 0.0039 0.003 0.003
Entamoeba histolytica cell division protein kinase 2, putative 0.0053 0.0059 0.0625
Echinococcus granulosus mitogen activated protein kinase 0.0061 0.0076 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Echinococcus granulosus neuropeptides capa receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0072 0.01 0.0989
Loa Loa (eye worm) GABA receptor subunit 0.0036 0.0023 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0072 0.01 0.01
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Brugia malayi G-protein coupled receptor 0.0072 0.01 0.01
Echinococcus multilocularis protein kinase c iota type 0.0034 0.002 0.002
Plasmodium falciparum histone deacetylase 1 0.0468 0.0946 1
Schistosoma mansoni protein kinase 0.0302 0.0591 0.0591
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0067 0.0089 0.0089
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0058 0.007 0.007
Trypanosoma brucei aurora B kinase 0.0302 0.0591 0.3189
Echinococcus multilocularis epidermal growth factor receptor 0.023 0.0436 0.0436
Schistosoma mansoni biogenic amine (5HT) receptor 0.0072 0.01 0.01
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0193 0.0358 0.0358
Onchocerca volvulus 0.0318 0.0625 0.6422
Echinococcus multilocularis nAChR subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis neuropeptides capa receptor 0.0072 0.01 0.01
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0053 0.0059 0.0299
Schistosoma mansoni histone deacetylase 0.0468 0.0946 0.0946
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0072 0.01 0.0097
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0058 0.007 0.0357
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0039 0.003 0.003
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0041 0.0034 0.0034
Echinococcus granulosus glycine receptor subunit beta 0.0067 0.0089 0.0089
Leishmania major C-8 sterol isomerase-like protein 0.0889 0.1844 1
Entamoeba histolytica protein kinase 2, putative 0.003 0.0011 0.0113
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis alpha 1,6 mannosyl glycoprotein 0.4713 1 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0057 0.0068 0.0068
Echinococcus multilocularis aurora kinase A 0.0302 0.0591 0.0591
Entamoeba histolytica protein kinase, putative 0.0027 0.0004 0.0047
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0032 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0122 0.0207 0.0204
Trypanosoma brucei histone deacetylase 2 0.0134 0.0232 0.1238
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Onchocerca volvulus Putative nachr subunit 0.0067 0.0089 0.0877
Echinococcus granulosus CDC7 cell division cycle 7 0.0067 0.0089 0.0089
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Echinococcus granulosus glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Loa Loa (eye worm) histone deacetylase 1 0.0468 0.0946 0.0943
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0029 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Schistosoma mansoni tyrosine kinase 0.0039 0.003 0.003
Trypanosoma cruzi histone deacetylase 1, putative 0.0468 0.0946 0.5118
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0057 0.0068 0.0068
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Entamoeba histolytica protein kinase , putative 0.0302 0.0591 0.6248
Brugia malayi Immunoglobulin I-set domain containing protein 0.0037 0.0026 0.0026
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.0113 0.0187 0.1889
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Echinococcus multilocularis serotonin receptor 0.0602 0.1231 0.1231
Giardia lamblia Kinase, CMGC MAPK 0.0061 0.0076 0.0805
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0053 0.0059 0.0299
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0015 0.0015
Brugia malayi hypothetical protein 0.0039 0.003 0.003
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0027 0.0005 0.0005
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Echinococcus multilocularis hemicentin 1 0.0038 0.0028 0.0028
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.018 0.033 0.033
Trichomonas vaginalis cyclins, putative 0.0032 0.0015 0.0155
Schistosoma mansoni cyclin B 0.0076 0.0109 0.0109
Echinococcus multilocularis cyclin dependent kinase 0.0053 0.0059 0.0059
Loa Loa (eye worm) TYRA-2 protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0049 0.0052 0.051
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Loa Loa (eye worm) hypothetical protein 0.0602 0.1231 0.1229
Onchocerca volvulus Neuropeptide F receptor homolog 0.0072 0.01 0.0989
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0015 0.0155
Trichomonas vaginalis cyclin B, putative 0.0032 0.0015 0.0155
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.005 0.0053 0.0265
Schistosoma mansoni acetylcholine receptor-related 0.0031 0.0012 0.0012
Trichomonas vaginalis AGC family protein kinase 0.003 0.0012 0.0122
Echinococcus granulosus alpha 16 mannosyl glycoprotein 0.4713 1 1
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0076 0.0392
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0072 0.01 0.01
Echinococcus multilocularis CDC7 cell division cycle 7 0.0067 0.0089 0.0089
Echinococcus multilocularis Immunoglobulin 0.0037 0.0026 0.0026
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0109 0.0109
Echinococcus granulosus neuropeptide Y receptor 0.0072 0.01 0.01
Brugia malayi serine/threonine-protein kinase 6 0.0302 0.0591 0.0591
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0023 0.0023
Loa Loa (eye worm) ACC-1 protein 0.0067 0.0089 0.0086
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0027 0.0005 0.0005
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.003 0.003
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0067 0.0089 0.0089
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0067 0.0089 0.0089
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0037 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus multilocularis tyrosine protein kinase shark 0.0256 0.0493 0.0493
Schistosoma mansoni tyrosine kinase 0.0256 0.0493 0.0493
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0004
Echinococcus multilocularis cyclin B 0.0076 0.0109 0.0109
Echinococcus multilocularis mitogen activated protein kinase 0.0061 0.0076 0.0076
Brugia malayi Protein kinase domain containing protein 0.0051 0.0056 0.0056
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0072 0.01 0.01
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0072 0.01 0.01
Echinococcus granulosus growth factor receptor bound protein 2 0.0039 0.003 0.003
Echinococcus multilocularis rac serine:threonine kinase 0.0032 0.0015 0.0015
Brugia malayi excitatory GABA receptor EXP-1A 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0072 0.01 0.0989
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0039 0.003 0.0316
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0023 0.0023
Echinococcus multilocularis serine threonine protein kinase 0.007 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0067 0.0089 0.0089
Plasmodium vivax protein kinase Crk2 0.0053 0.0059 0.0518
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0053 0.0059 0.0584
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.005 0.0053 0.0053
Brugia malayi histone deacetylase 3 (HD3) 0.0468 0.0946 0.0946
Onchocerca volvulus 0.0067 0.0089 0.0877
Echinococcus multilocularis neuropeptide receptor 0.0072 0.01 0.01
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0028 0.0007 0.0007
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0051 0.0055 0.0052
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Brugia malayi Cation transporter family protein 0.0067 0.0089 0.0089
Trichomonas vaginalis cyclins, putative 0.0076 0.0109 0.1157
Echinococcus granulosus serine:threonine protein kinase NIM1 0.0093 0.0145 0.0145
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0076 0.0109 0.0109
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0122 0.0207 0.1101
Echinococcus multilocularis g protein coupled receptor 0.0072 0.01 0.01
Giardia lamblia Kinase, CMGC GSK 0.0058 0.007 0.0738
Brugia malayi Tyrosine-protein kinase abl-1 0.0138 0.024 0.024
Schistosoma mansoni nAChR subunit 0.0031 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Onchocerca volvulus Putative titin 0.0031 0.0013 0.0088
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0032 0.0015 0.0015
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Brugia malayi map kinase activated protein kinase protein 2 0.0193 0.0358 0.0358
Echinococcus multilocularis g protein coupled receptor 0.0072 0.01 0.01
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0031 0.0012 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.0089 0.0944
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0067 0.0089 0.0089
Schistosoma mansoni beta-12-n-acetylglucosaminyltransferase II 0.4713 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0053 0.0059 0.0056
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0061 0.0076 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis neuropeptides capa receptor 0.0072 0.01 0.01
Leishmania major protein kinase A catalytic subunit isoform 2 0.005 0.0053 0.0265
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0137 0.024 0.1281
Schistosoma mansoni neuropeptide f receptor 76f 0.0072 0.01 0.01
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0031 0.0012 0.0012
Schistosoma mansoni acetylcholine receptor subunit beta 0.0031 0.0012 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Echinococcus multilocularis histone deacetylase 8 0.0134 0.0232 0.0232
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0468 0.0946 1
Trichomonas vaginalis STE family protein kinase 0.0113 0.0187 0.1981
Giardia lamblia Aurora kinase 0.0302 0.0591 0.6248
Echinococcus granulosus histone deacetylase 6 0.0134 0.0232 0.0232
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Echinococcus multilocularis serotonin receptor 0.0602 0.1231 0.1231
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0061 0.0076 0.0392
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0015 0.016
Echinococcus granulosus serine threonine protein kinase 0.0113 0.0187 0.0187
Leishmania major cyclin 0.0076 0.0109 0.0573
Leishmania major protein kinase A catalytic subunit 0.005 0.0053 0.0265
Loa Loa (eye worm) AGC/AKT protein kinase 0.0051 0.0056 0.0053
Brugia malayi serine/threonine kinase 12 0.0302 0.0591 0.0591
Trichomonas vaginalis histone deacetylase, putative 0.0468 0.0946 1
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0302 0.0591 0.6248
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0036 0.0023 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0358 0.0358
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.0093 0.0145 0.0142
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Schistosoma mansoni adenoreceptor 0.0072 0.01 0.01
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0037 0.0026 0.0026
Entamoeba histolytica PH domain containing protein kinase, putative 0.0052 0.0057 0.0606
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Onchocerca volvulus 0.0093 0.0145 0.1455
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0122 0.0207 0.0207
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) ACC-1 protein 0.0067 0.0089 0.0086
Entamoeba histolytica cyclin, putative 0.0076 0.0109 0.1157
Plasmodium falciparum cyclin 0.0032 0.0015 0.0112
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0039 0.0029 0.0029
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0058 0.007 0.0067
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0023 0.002
Echinococcus granulosus neuropeptides capa receptor 0.0072 0.01 0.01
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0041 0.0034 0.0034
Schistosoma mansoni adapter molecule crk 0.0039 0.003 0.003
Trypanosoma brucei mitotic cyclin 6 0.0076 0.0109 0.0573
Schistosoma mansoni growth hormone secretagogue receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus orexin receptor type 2 0.0072 0.01 0.01
Brugia malayi G protein-coupled receptor F59B2.13 0.0072 0.01 0.01
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Loa Loa (eye worm) AUR protein kinase 0.0302 0.0591 0.0588
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0053 0.0053
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0026 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Brugia malayi Protein kinase domain containing protein 0.018 0.033 0.033
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0229 0.0435 0.0435
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0067 0.0089 0.0089
Entamoeba histolytica protein kinase, putative 0.0302 0.0591 0.6248
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0159 0.0286 0.0286
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0027 0.0005 0.0002
Schistosoma mansoni histone deacetylase 0.0468 0.0946 0.0946
Echinococcus multilocularis somatostatin receptor 0.0072 0.01 0.01
Echinococcus multilocularis cyclin b3 0.0032 0.0015 0.0015
Entamoeba histolytica protein kinase, putative 0.0051 0.0056 0.0595
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Schistosoma mansoni histone deacetylase hda2 0.0134 0.0232 0.0232
Brugia malayi neuropeptide F receptor 0.0072 0.01 0.01
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0089 0.0089
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0013
Brugia malayi Histone deacetylase 1 0.0468 0.0946 0.0946
Echinococcus granulosus neuroglian 0.0046 0.0045 0.0045
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0122 0.0207 0.0207
Schistosoma mansoni tyrosine kinase 0.023 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) hypothetical protein 0.0047 0.0046 0.0043
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Schistosoma mansoni tyrosine kinase 0.0057 0.0068 0.0068
Echinococcus multilocularis glycine receptor subunit beta 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Brugia malayi Variant SH3 domain containing protein 0.0027 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0044 0.0042 0.0039
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.005 0.0053 0.0265
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0058 0.007 0.007
Onchocerca volvulus 0.0067 0.0089 0.0877
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0059 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0067 0.0089 0.0944
Brugia malayi Dopamine receptor 0.0072 0.01 0.01
Echinococcus granulosus activin receptor type 0.0027 0.0004 0.0004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0061 0.0076 0.0392
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0072 0.01 0.01
Schistosoma mansoni biogenic amine receptor 0.0072 0.01 0.01
Loa Loa (eye worm) histone deacetylase 11 0.0134 0.0232 0.0229
Schistosoma mansoni nAChR subunit 0.0067 0.0089 0.0089
Trichomonas vaginalis cyclin A, putative 0.0076 0.0109 0.1157
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus tyrosine protein kinase Fyn 0.0057 0.0068 0.0068
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) histone deacetylase 7A 0.0134 0.0232 0.0229
Giardia lamblia Kinase, CMGC CDK 0.0053 0.0059 0.0625
Brugia malayi Histone deacetylase family protein 0.0134 0.0232 0.0232
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0061 0.0076 0.0392
Echinococcus granulosus glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Onchocerca volvulus 0.0072 0.01 0.0989
Echinococcus multilocularis mitogen activated protein kinase 14 0.0137 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Brugia malayi intracellular kinase 0.0058 0.007 0.007
Giardia lamblia Cyclin A 0.0032 0.0015 0.0155
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0028 0.0007 0.0007
Onchocerca volvulus 0.0067 0.0089 0.0877
Trypanosoma cruzi histone deacetylase, putative 0.0134 0.0232 0.1238
Schistosoma mansoni cyclin B3 0.0032 0.0015 0.0015
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0067 0.0089 0.0089
Echinococcus multilocularis nAChR subunit 0.0036 0.0023 0.0023
Schistosoma mansoni atypical protein kinase C 0.0034 0.002 0.002
Entamoeba histolytica serine/threonine protein kinase, putative 0.0105 0.0171 0.1813
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus neuropeptide receptor 0.0072 0.01 0.01
Echinococcus granulosus glycine receptor subunit alpha 1 0.0067 0.0089 0.0089
Loa Loa (eye worm) TK/FER protein kinase 0.0039 0.003 0.0027
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0067 0.0089 0.0089
Schistosoma mansoni amine GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0697 0.1433 0.1433
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0043 0.0038 0.0182
Leishmania major histone deacetylase, putative 0.0134 0.0232 0.1238
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Echinococcus multilocularis Immunoglobulin 0.0037 0.0026 0.0026
Onchocerca volvulus 0.0067 0.0089 0.0877
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0591 0.0591
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0072 0.01 0.01
Entamoeba histolytica cyclin, putative 0.0032 0.0015 0.0155
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0015 0.0015
Echinococcus granulosus neuropeptide receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Trichomonas vaginalis CMGC family protein kinase 0.0061 0.0076 0.0805
Echinococcus multilocularis mitogen activated protein kinase 11 0.0137 0.024 0.024
Schistosoma mansoni neurotransmitter gated ion channel 0.0036 0.0023 0.0023
Brugia malayi Cation transporter family protein 0.0067 0.0089 0.0089
Brugia malayi putative neuropeptide receptor NPR1 0.0072 0.01 0.01
Brugia malayi Immunoglobulin I-set domain containing protein 0.038 0.0757 0.0757
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.005 0.0053 0.0265
Trichomonas vaginalis cyclin B, putative 0.0076 0.0109 0.1157
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0038 0.0028 0.0242
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0302 0.0591 0.6205
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Brugia malayi Protein kinase domain containing protein 0.0028 0.0007 0.0007
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0137 0.024 0.0237
Brugia malayi Variant SH3 domain containing protein 0.0039 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0084 0.0126 0.0123
Entamoeba histolytica protein kinase domain containing protein 0.0027 0.0004 0.0043
Echinococcus multilocularis c src tyrosine kinase 0.0057 0.0068 0.0068
Entamoeba histolytica protein kinase, putative 0.0051 0.0056 0.0595
Trypanosoma cruzi histone deacetylase 1, putative 0.0468 0.0946 0.5118
Trypanosoma cruzi cyclin, putative 0.0076 0.0109 0.0573
Brugia malayi histone deacetylase 11 0.0134 0.0232 0.0232
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0072 0.01 0.01
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Schistosoma mansoni tyrosine kinase 0.0034 0.0019 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.0057 0.0067 0.0712
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0031 0.0012 0.0012
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0072 0.01 0.01
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0067 0.0089 0.0089
Echinococcus granulosus RNA directed DNA polymerase 0.004 0.0033 0.0033
Trypanosoma cruzi aurora B kinase, putative 0.0302 0.0591 0.3189
Loa Loa (eye worm) SRC-1 0.0057 0.0068 0.0065
Schistosoma mansoni histone deacetylase 4 5 0.0134 0.0232 0.0232
Echinococcus multilocularis serine:threonine protein kinase N2 0.0028 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.0199 0.0371 0.0371
Brugia malayi hypothetical protein 0.0072 0.01 0.01
Brugia malayi p70 ribosomal S6 kinase beta 0.0049 0.0052 0.0052
Echinococcus multilocularis G-protein coupled receptor, putative 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0455 0.0916 0.0914
Loa Loa (eye worm) TK protein kinase 0.0127 0.0218 0.0215
Schistosoma mansoni protein kinase 0.0027 0.0004 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Echinococcus granulosus g-protein coupled receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus c src tyrosine kinase 0.0057 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0057 0.0068 0.0068
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0031 0.0012 0.0012
Trichomonas vaginalis AGC family protein kinase 0.0051 0.0056 0.0595
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0067 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0039 0.003 0.003
Brugia malayi Protein kinase domain containing protein 0.0067 0.0089 0.0089
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0072 0.01 0.01
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0067 0.0089 0.0089
Trichomonas vaginalis cyclin D, putative 0.0032 0.0015 0.0155
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0889 0.1844 1
Echinococcus granulosus cyclin b3 0.0032 0.0015 0.0015
Giardia lamblia Hypothetical protein 0.0032 0.0015 0.0155
Echinococcus multilocularis sex peptide receptor 0.0072 0.01 0.01
Brugia malayi putative neuropeptide receptor 0.0072 0.01 0.01
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0026 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0044 0.0041 0.0038
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0028 0.0007 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0072 0.01 0.0097
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.005 0.0053 0.0265
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0028 0.0007 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0072 0.01 0.01
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0697 0.1433 0.1433
Toxoplasma gondii aurora kinase 0.0302 0.0591 0.6231
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus cyclin dependent kinase 5 0.0053 0.0059 0.0059
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.004 0.0033 0.0033
Leishmania major protein kinase, putative 0.0302 0.0591 0.3189
Brugia malayi hypothetical protein 0.0031 0.0012 0.0012
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0119 0.02 0.02
Loa Loa (eye worm) hypothetical protein 0.4713 1 1
Plasmodium vivax histone deacetylase 1, putative 0.0468 0.0946 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Brugia malayi Tachykinin-like peptides receptor 99D 0.0072 0.01 0.01
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0171 0.1813
Brugia malayi G-protein coupled receptor 0.0072 0.01 0.01
Loa Loa (eye worm) histone deacetylase 3 0.0468 0.0946 0.0943
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Echinococcus granulosus neuropeptide Y receptor 0.0072 0.01 0.01
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.005 0.0053 0.0265
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.0171 0.091
Schistosoma mansoni hypothetical protein 0.0072 0.01 0.01
Toxoplasma gondii AGC kinase 0.0049 0.0052 0.0506
Echinococcus multilocularis fmrfamide receptor 0.0072 0.01 0.01
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0067 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0033 0.0018 0.0015
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Echinococcus granulosus Immunoglobulin 0.0037 0.0026 0.0026
Echinococcus multilocularis cyclins 0.0032 0.0015 0.0015
Brugia malayi P38 map kinase family protein 2 0.0137 0.024 0.024
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0072 0.01 0.01
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0302 0.0591 0.0591
Schistosoma mansoni neuropeptide F-like receptor 0.0072 0.01 0.01
Brugia malayi Protein kinase domain containing protein 0.0053 0.0059 0.0059
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0468 0.0946 1
Brugia malayi protein-tyrosine kinase 0.0039 0.003 0.003
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0058 0.007 0.0357
Loa Loa (eye worm) hypothetical protein 0.0072 0.01 0.0097
Onchocerca volvulus 0.0067 0.0089 0.0879
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0072 0.01 0.01
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0199 0.0371 0.0371
Giardia lamblia Kinase, AGC PKA 0.003 0.0011 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Brugia malayi Cyclin, N-terminal domain containing protein 0.0076 0.0109 0.0109
Echinococcus granulosus mitogen activated protein kinase 14 0.0137 0.024 0.024
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0072 0.01 0.01
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0145 0.0145
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0057 0.0057
Echinococcus granulosus cyclin B 0.0076 0.0109 0.0109
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0137 0.024 0.1281
Echinococcus granulosus hypothetical protein 0.0072 0.01 0.01
Echinococcus granulosus cyclin dependent kinase 0.0053 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0067 0.0089 0.0086
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0105 0.0171 0.091
Toxoplasma gondii histone deacetylase HDAC5 0.0134 0.0232 0.2418
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0468 0.0946 1
Schistosoma mansoni tyrosine kinase 0.0159 0.0286 0.0286
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0039 0.003 0.003
Echinococcus granulosus neuropeptide s receptor 0.0072 0.01 0.01
Schistosoma mansoni vesicular amine transporter 0.004 0.0032 0.0032
Loa Loa (eye worm) G-protein coupled receptor 0.0072 0.01 0.0097
Echinococcus multilocularis neuropeptide Y receptor 0.0072 0.01 0.01
Trypanosoma brucei protein kinase, putative 0.0058 0.007 0.0357
Schistosoma mansoni neuropeptide receptor 0.0072 0.01 0.01
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Echinococcus granulosus cyclins 0.0032 0.0015 0.0015
Onchocerca volvulus 0.0031 0.0012 0.0083
Echinococcus granulosus allatostatin A receptor 0.0072 0.01 0.01
Brugia malayi Cation transporter family protein 0.0067 0.0089 0.0089
Trypanosoma brucei histone deacetylase, putative 0.0134 0.0232 0.1238
Echinococcus granulosus epidermal growth factor receptor 0.023 0.0436 0.0436
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0122 0.0207 0.0207
Loa Loa (eye worm) neuropeptide F receptor 0.0072 0.01 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0072 0.01 0.01
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.005 0.0053 0.0518
Giardia lamblia Kinase, CMGC CDK 0.0053 0.0059 0.0625
Echinococcus multilocularis tyrosine protein kinase ABL1 0.025 0.048 0.048
Entamoeba histolytica protein kinase, putative 0.0113 0.0187 0.1981
Brugia malayi cell division control protein 2 homolog 0.0093 0.0145 0.0145
Schistosoma mansoni myosin xvIII 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0084 0.0126 0.0123
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0031 0.0012 0.0009
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0043 0.0038 0.0182
Echinococcus granulosus histone deacetylase 8 0.0134 0.0232 0.0232
Schistosoma mansoni opsin-like receptor 0.0072 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0009
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0072 0.01 0.01
Echinococcus granulosus aurora kinase A 0.0302 0.0591 0.0591
Echinococcus multilocularis allatostatin A receptor 0.0072 0.01 0.01
Echinococcus multilocularis mitogen activated protein kinase 11 0.0137 0.024 0.024
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0007 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0072 0.01 0.01
Onchocerca volvulus 0.0039 0.003 0.0264
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0105 0.0171 0.0171
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0067 0.0089 0.0086
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0053 0.0059 0.0056
Onchocerca volvulus 0.0072 0.01 0.0989
Plasmodium falciparum histone deacetylase, putative 0.0134 0.0232 0.2418
Echinococcus multilocularis growth factor receptor bound protein 2 0.0039 0.003 0.003

Activities

Activity type Activity value Assay description Source Reference
AD50 (functional) = 0.05 mg kg-1 Antinociceptive activity was determined at Opioid receptor delta 1 using DPDPE ChEMBL. 11150174
AD50 (functional) = 1.2 mg kg-1 Antinociceptive activity was determined at Opioid receptor delta 1 versus ED80 of U69,593 ChEMBL. 11150174
AD50 (functional) = 20 mg kg-1 Antinociceptive activity was determined at Opioid receptor delta 1 versus ED80 of morphine ChEMBL. 11150174
ED50 (functional) mg kg-1 Evaluated in vivo for the antinociceptive and opioid antagonist assays in ICR male mice, Tail-Flick agonist and antagonist tests weas performed;IA,Inactive less than 70% of mice affected at 30 mg/kg. ChEMBL. 11150174
ED50 (functional) mg kg-1 Hot plate test was carried out for mouse injected sc and the antinociceptive activity was determined from the response;IA,Inactive less than 70% of mice affected at 30 mg/kg. ChEMBL. 11150174
ED50 (functional) = 12 mg kg-1 Using the PPQ(paraphenylquinone) assay selective opioid receptor agonist activity was established in mice ChEMBL. 11150174
Ki (binding) = 11 nM Ki value determined against Opioid receptor kappa 1 using [3H]U69, 593 at the Kd concentration 0.95 nM ChEMBL. 11150174
Ki (binding) = 18 nM Ki value determined against Opioid receptor mu 1 using [3H]-DAMGO at the Kd concentration 0.57 nM ChEMBL. 11150174
Ki (binding) = 140 nM Ki value determined against Opioid receptor delta 1 using [3H]-DPDPE at the Kd concentration 2.1 nM ChEMBL. 11150174
Ki (binding) = 200 nM Ki value determined against Sigma opioid receptor type 1 ChEMBL. 11150174

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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