Detailed information for compound 1748451

Basic information

Technical information
  • TDR Targets ID: 1748451
  • Name: (4-dimethylaminophenyl)iminosulfamic acid
  • MW: 229.256 | Formula: C8H11N3O3S
  • H donors: 1 H acceptors: 3 LogP: 1.34 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(c1ccc(cc1)N=NS(=O)(=O)O)C
  • InChi: 1S/C8H11N3O3S/c1-11(2)8-5-3-7(4-6-8)9-10-15(12,13)14/h3-6H,1-2H3,(H,12,13,14)
  • InChiKey: FLTYACUMGDVPLP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Benzenediazosulfonic acid, p-(dimethylamino)-
  • Diazenesulfonic acid, (4-(dimethylamino)phenyl)-
  • dexon (fungicide)
  • p-(Dimethylamino)benzenediazosulfonic acid
  • p-Dimethylaminodiazobenzenesulfonic acid
  • ZINC02040981

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0299 0.1772 0.1772
Brugia malayi Cytochrome P450 family protein 0.002 0.0036 0.0201
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0794 0.4853 1
Echinococcus granulosus FK506 binding protein 2 0.0041 0.0169 0.0397
Loa Loa (eye worm) hypothetical protein 0.0151 0.0855 0.4827
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0299 0.1772 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.1157 0.2713
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0036 0.0202
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0299 0.1772 1
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0036 0.0201
Schistosoma mansoni topbp1 0.002 0.0036 0.0084
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0985
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.4264 1
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0036 0.0202
Schistosoma mansoni topbp1 0.002 0.0036 0.0084
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0041 0.0169 0.0768
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0134 0.0314
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0068 0.014
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0036 0.0202
Mycobacterium ulcerans hypothetical protein 0.0047 0.0208 0.1176
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0036 0.0201
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0208 0.1176
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0755
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0755
Leishmania major fk506-binding protein 1-like protein 0.0299 0.1772 1
Leishmania major peptidylprolyl isomerase-like protein 0.0299 0.1772 1
Loa Loa (eye worm) hypothetical protein 0.0151 0.0855 0.4827
Echinococcus multilocularis 0.0041 0.0169 0.0169
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0134 0.0755
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0134 0.0755
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0041 0.0169 1
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0036 0.0074
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0068 0.0384
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0208 0.1176
Loa Loa (eye worm) hypothetical protein 0.0047 0.0208 0.1176
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.002 0.0036 0.1722
Echinococcus multilocularis muscleblind protein 0.0151 0.0855 0.0855
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0208 0.1176
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0855 0.0855
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0299 0.1772 1
Schistosoma mansoni immunophilin 0.0299 0.1772 0.4155
Echinococcus multilocularis expressed conserved protein 0.0185 0.1064 0.1064
Schistosoma mansoni fk506 binding protein 0.0041 0.0169 0.0397
Schistosoma mansoni immunophilin 0.0258 0.1516 0.3555
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0041 0.0169 0.0349
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0208 0.1176
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0208 0.1176
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0208 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0755
Trichomonas vaginalis fk506-binding protein, putative 0.0041 0.0169 0.0955
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0041 0.0169 0.0768
Brugia malayi hypothetical protein 0.0016 0.0013 0.0075
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.1138 0.1138
Entamoeba histolytica hypothetical protein 0.0035 0.0134 0.0757
Entamoeba histolytica hypothetical protein 0.002 0.0036 0.0202
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0036 0.0202
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0134 0.0314
Schistosoma mansoni survival motor neuron protein 0.0048 0.0209 0.0491
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0134 0.0755
Loa Loa (eye worm) FKBP5 protein 0.0299 0.1772 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0036 0.0202
Schistosoma mansoni hypothetical protein 0.0048 0.0209 0.0491
Echinococcus multilocularis tumor protein p63 0.0333 0.1986 0.1986
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0258 0.1516 0.3555
Onchocerca volvulus 0.0049 0.0217 0.2061
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0036 0.0202
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0208 0.1176
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0202
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0041 0.0169 0.0768
Leishmania major hypothetical protein, conserved 0.0025 0.0068 0.0384
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0299 0.1772 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0439 0.2477
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0439 0.0439
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0208 0.1176
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0036 0.0074
Brugia malayi hypothetical protein 0.0025 0.0068 0.0384
Onchocerca volvulus 0.0041 0.0169 0.1608
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0036 0.0202
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.1138 0.6423
Loa Loa (eye worm) hypothetical protein 0.0049 0.0217 0.1223
Chlamydia trachomatis peptidyl-prolyl cis-trans isomerase 0.0794 0.4853 1
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0299 0.1772 1
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-33 0.0041 0.0169 0.0955
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.1138 0.6423
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0299 0.1772 0.4155
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0299 0.1772 1
Trypanosoma cruzi FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Schistosoma mansoni patched 1 0.0084 0.0439 0.1029
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0985
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0439 0.1029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0134 0.0134
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0036 0.0202
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0217 0.0508
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0755
Echinococcus granulosus muscleblind protein 0.0151 0.0855 0.2006
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0208 0.1176
Echinococcus granulosus FK506 binding protein 8 38 kDa 0.0041 0.0169 0.0397
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0202
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0036 0.0202
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0068 0.0384
Onchocerca volvulus 0.0041 0.0169 0.1608
Giardia lamblia Hypothetical protein 0.0041 0.0169 0.0768
Mycobacterium tuberculosis Probable trigger factor (TF) protein Tig 0.0041 0.0169 0.812
Trichomonas vaginalis fk506-binding protein, putative 0.0041 0.0169 0.0955
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0208 0.1176
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0299 0.1772 1
Wolbachia endosymbiont of Brugia malayi FKBP-type peptidylprolyl isomerase 0.0041 0.0169 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0036 0.0202
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0036 0.0201
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0208 0.1176
Loa Loa (eye worm) hypothetical protein 0.0233 0.1364 0.7697
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0122 0.5844
Mycobacterium leprae PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG 0.0041 0.0169 0.812
Toxoplasma gondii peptidyl-prolyl cis-trans isomerase, FKBP-type domain-containing protein 0.0041 0.0169 0.0349
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0208 0.1176
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0122 0.5844
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0299 0.1772 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0068 0.0384
Loa Loa (eye worm) hypothetical protein 0.0197 0.1138 0.6423
Brugia malayi N-terminal motif family protein 0.0183 0.1052 0.5936
Plasmodium vivax peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0299 0.1772 0.4155
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0134 0.0203
Brugia malayi Muscleblind-like protein 0.0151 0.0855 0.4827
Echinococcus multilocularis FK506 binding protein 8, 38 kDa 0.0041 0.0169 0.0169
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0202
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0068 0.0384
Onchocerca volvulus 0.002 0.0036 0.0341
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0036 0.0201
Brugia malayi hypothetical protein 0.002 0.0036 0.0202
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0036 0.0202
Loa Loa (eye worm) hypothetical protein 0.0103 0.0557 0.3145
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0208 0.1176
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-13, BmFKBP-13 0.0041 0.0169 0.0955
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0299 0.1772 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0202
Echinococcus multilocularis protein patched 0.0084 0.0439 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0439 0.2477
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0202
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0299 0.1772 1
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0439 0.1029
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0169 0.0955
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0258 0.1516 0.1516
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0299 0.1772 1
Mycobacterium ulcerans hypothetical protein 0.0041 0.0169 0.0955
Loa Loa (eye worm) hypothetical protein 0.002 0.0036 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0036 0.0202
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0036 0.0202
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Entamoeba histolytica hypothetical protein 0.0035 0.0134 0.0757
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0985
Entamoeba histolytica hypothetical protein 0.0035 0.0134 0.0757
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0755
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0036 0.0202
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0036 0.0202
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type (slyD) 0.0041 0.0169 0.0208
Schistosoma mansoni immunophilin 0.0299 0.1772 0.4155
Leishmania major peptidyl-prolyl cis-trans isomerase, macrophage infectivity potentiator precursor, putative 0.0041 0.0169 0.0955
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0208 1
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0299 0.1772 1
Leishmania major FKBP-type peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0208 0.1176
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0036 0.0202
Loa Loa (eye worm) CYP4Cod1 0.002 0.0036 0.0201
Schistosoma mansoni DNA ligase IV 0.002 0.0036 0.0084
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Echinococcus multilocularis Niemann Pick C1 protein 0.0281 0.1664 0.1664
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0122 0.5844
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0036 0.0202
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0122 0.5844
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0084 0.0439 0.2477
Loa Loa (eye worm) hypothetical protein 0.0041 0.0169 0.0955
Brugia malayi Cytochrome P450 family protein 0.003 0.0101 0.0568
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0134 0.6421
Schistosoma mansoni hypothetical protein 0.0081 0.042 0.0985
Trypanosoma brucei macrophage infectivity potentiator, precursor, putative 0.0041 0.0169 0.0955
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0208 0.1176
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.1138 0.2669
Trichomonas vaginalis fk506-binding protein, putative 0.0299 0.1772 1
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0299 0.1772 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0209 0.1181
Echinococcus granulosus expressed conserved protein 0.0185 0.1064 0.2495
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0036 0.0036
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.1364 0.1364
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0208 0.1176
Entamoeba histolytica hypothetical protein 0.0035 0.0134 0.0757
Echinococcus multilocularis fk506 binding protein 0.0299 0.1772 0.1772
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-30, BmFKBP-30 0.0041 0.0169 0.0955
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0041 0.0169 0.0955
Echinococcus multilocularis nibrin 0.002 0.0036 0.0036
Echinococcus granulosus nibrin 0.002 0.0036 0.0084
Loa Loa (eye worm) hypothetical protein 0.0183 0.1052 0.5936
Trypanosoma brucei FKBP-type peptidylprolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Trypanosoma cruzi macrophage infectivity potentiator, precursor, putative 0.0041 0.0169 0.0955
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0036 0.0202
Loa Loa (eye worm) hypothetical protein 0.0047 0.0208 0.1176
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0299 0.1772 1
Toxoplasma gondii peptidyl-prolyl isomerase FKBP12, putative 0.0041 0.0169 0.0349
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0299 0.1772 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0208 1
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0036 0.0201
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0036 0.0202
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.4264 0.4264
Brugia malayi Cytochrome P450 family protein 0.002 0.0036 0.0201
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.1364 0.3198
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0036 0.0202
Echinococcus granulosus microtubule associated protein 2 0.0699 0.4264 1
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-30 0.0041 0.0169 0.0955
Brugia malayi CHE-14 protein 0.0084 0.0439 0.2477
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0101 0.0568
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0068 0.0384
Trichomonas vaginalis immunophilin, putative 0.0299 0.1772 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0169 0.0955
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-13 0.0041 0.0169 0.0955
Brugia malayi hypothetical protein 0.0233 0.1364 0.7697
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-33, BmFKBP-33 0.0041 0.0169 0.0955
Echinococcus granulosus replication factor c subunit 1 0.002 0.0036 0.0084
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.1051 0.6456 1
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0299 0.1772 1
Echinococcus granulosus Niemann Pick C1 protein 0.0281 0.1664 0.3901
Trichomonas vaginalis fk506 binding protein, putative 0.0041 0.0169 0.0955
Echinococcus granulosus tumor protein p63 0.0333 0.1986 0.4657
Loa Loa (eye worm) hypothetical protein 0.0258 0.1516 0.8557
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0041 0.0169 0.0955
Brugia malayi hypothetical protein 0.0035 0.0134 0.0757
Brugia malayi topoisomerase 0.002 0.0036 0.0202
Onchocerca volvulus 0.0048 0.0209 0.199
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0036 0.0202
Schistosoma mansoni hypothetical protein 0.0035 0.0134 0.0314
Schistosoma mansoni hypothetical protein 0.0041 0.0169 0.0397
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0068 0.0384
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0208 0.1176
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0299 0.1772 1
Echinococcus multilocularis protein dispatched 1 0.0096 0.0513 0.0513
Brugia malayi hypothetical protein 0.002 0.0036 0.0202
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0068 0.0384
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0208 1
Onchocerca volvulus 0.0047 0.0208 0.1981
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0299 0.1772 0.4155
Trypanosoma brucei cytochrome P450, putative 0.002 0.0036 0.0201
Loa Loa (eye worm) hypothetical protein 0.0047 0.0208 0.1176
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0299 0.1772 1
Brugia malayi DKFZp564C0469 protein 0.002 0.0036 0.0202
Leishmania major cytochrome p450-like protein 0.002 0.0036 0.0201
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.1052 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0169 0.0955

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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