Detailed information for compound 1755590

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 453.579 | Formula: C28H31N5O
  • H donors: 1 H acceptors: 3 LogP: 4.21 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C)C(=O)NCCc1nnc2n1CCN(CC2)Cc1ccc2c(c1)cccc2
  • InChi: 1S/C28H31N5O/c1-20-7-10-25(21(2)17-20)28(34)29-13-11-26-30-31-27-12-14-32(15-16-33(26)27)19-22-8-9-23-5-3-4-6-24(23)18-22/h3-10,17-18H,11-16,19H2,1-2H3,(H,29,34)
  • InChiKey: KIPINZGDSJKXLH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.117 0.2644
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0068 0.1107 0.2201
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0469 0.2376
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.1054 0.2381
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0068 0.1107 0.8081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0517 0.2807
Loa Loa (eye worm) hypothetical protein 0.0078 0.1322 0.2987
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.1228 0.2412
Entamoeba histolytica hypothetical protein 0.0038 0.0501 0.0499
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.1322 0.0832
Trichomonas vaginalis chromobox protein, putative 0.0071 0.117 0.8642
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0715 0.1245
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0674 0.1513
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0534 0.2964
Echinococcus granulosus lamin dm0 0.0026 0.025 0.0111
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0458
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0501 0.0701
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0715 0.1205
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0715 0.1205
Brugia malayi Ets-domain containing protein 0.0074 0.1228 0.2757
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1054 0.207
Entamoeba histolytica hypothetical protein 0.0038 0.0501 0.0499
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Schistosoma mansoni lamin 0.0026 0.025 0.0114
Brugia malayi Heterochromatin protein 1 0.0071 0.117 0.2628
Schistosoma mansoni chromobox protein 0.0071 0.117 0.2354
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0715 0.1245
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0517 0.2807
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.1034 0.2022
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.3122 0.6869
Mycobacterium ulcerans beta-lactamase 0.0078 0.1322 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0068 0.1107 0.8081
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0534 0.2964
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.1034 0.0527
Echinococcus multilocularis musashi 0.0026 0.025 0.0111
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.1054 0.2367
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.1322 0.0832
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.1322 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0715 0.1605
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Schistosoma mansoni chromobox protein 0.0071 0.117 0.2354
Brugia malayi Peptidase family M1 containing protein 0.0068 0.1107 0.2487
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0469 0.2376
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.1322 0.2635
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0534 0.2964
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0469 0.2376
Brugia malayi hypothetical protein 0.0229 0.4426 0.9941
Entamoeba histolytica hypothetical protein 0.0038 0.0501 0.0499
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0517 0.0755
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.3122 0.6869
Echinococcus granulosus lamin 0.0026 0.025 0.0111
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.1322 1
Mycobacterium tuberculosis Conserved protein 0.0078 0.1322 0.0832
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.1034 0.1955
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.1322 0.2724
Onchocerca volvulus 0.0026 0.025 0.0111
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.1034 0.7422
Onchocerca volvulus 0.0026 0.025 0.0111
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.4426 0.9938
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0291 0.0787
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.1322 1
Leishmania major hypothetical protein, conserved 0.0078 0.1322 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.1322 0.0832
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1054 0.207
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0469 0.2376
Schistosoma mansoni survival motor neuron protein 0.0047 0.0674 0.1146
Loa Loa (eye worm) hypothetical protein 0.0162 0.3057 0.6907
Loa Loa (eye worm) hypothetical protein 0.004 0.0529 0.1196
Mycobacterium leprae Probable lipase LipE 0.0078 0.1322 0.5
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.1322 0.0832
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0715 0.1205
Entamoeba histolytica hypothetical protein 0.0038 0.0501 0.0499
Loa Loa (eye worm) beta-lactamase 0.0078 0.1322 0.2987
Schistosoma mansoni alpha-glucosidase 0.0142 0.2647 0.5946
Onchocerca volvulus 0.0078 0.1322 0.2635
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.1322 0.2987
Mycobacterium tuberculosis Conserved protein 0.0078 0.1322 0.0832
Brugia malayi beta-lactamase family protein 0.0078 0.1322 0.297
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0534 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0469 0.2376
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0529 0.2919
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0068 0.1107 0.8081
Brugia malayi intermediate filament protein 0.0026 0.025 0.0561
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0469 0.2376
Brugia malayi TATA binding protein associated factor 0.0024 0.0203 0.0455
Loa Loa (eye worm) hypothetical protein 0.0078 0.1322 0.2987
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Brugia malayi hypothetical protein 0.0038 0.0501 0.1124
Onchocerca volvulus 0.0078 0.1322 0.2635
Echinococcus multilocularis aminopeptidase N 0.023 0.4453 1
Brugia malayi Peptidase family M1 containing protein 0.023 0.4453 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.4426 1
Schistosoma mansoni intermediate filament proteins 0.0026 0.025 0.0114
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.3122 0.7012
Brugia malayi chromobox protein homolog 3 0.004 0.0529 0.1189
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.025 0.0561
Brugia malayi hypothetical protein 0.0068 0.1107 0.2487
Loa Loa (eye worm) fli-1 protein 0.0223 0.4314 0.9746
Loa Loa (eye worm) hypothetical protein 0.0026 0.024 0.0542
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.1034 0.7422
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0469 0.2376
Echinococcus multilocularis chromobox protein 1 0.0071 0.117 0.2277
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.1322 0.2724
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.1322 1
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.4426 0.9938
Mycobacterium ulcerans lipase LipD 0.0078 0.1322 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.1322 0.2987
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.2241 0.5062
Echinococcus granulosus aminopeptidase N 0.023 0.4453 1
Mycobacterium ulcerans hypothetical protein 0.0078 0.1322 1
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0044 0.0617 0.1008
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.1228 0.2412
Brugia malayi Peptidase family M1 containing protein 0.0024 0.0203 0.0455
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1394
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0534 0.12
Loa Loa (eye worm) hypothetical protein 0.0026 0.025 0.0564
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.1322 0.297
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0458
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0469 0.2376
Loa Loa (eye worm) TATA binding protein associated factor 0.0024 0.0203 0.0458
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0517 0.074
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0517 0.2807
Loa Loa (eye worm) intermediate filament protein 0.0026 0.025 0.0564
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0469 0.2376
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1054 0.207
Echinococcus multilocularis tar DNA binding protein 0.0065 0.1054 0.2003
Toxoplasma gondii exonuclease III APE 0.004 0.0534 0.2964
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0068 0.1107 0.8081
Plasmodium vivax hypothetical protein, conserved 0.0078 0.1322 1
Schistosoma mansoni ap endonuclease 0.004 0.0534 0.0807
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0534 0.2964
Loa Loa (eye worm) peptidase family M1 containing protein 0.0186 0.3548 0.8015
Brugia malayi TAR-binding protein 0.0065 0.1054 0.2367
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0517 0.074
Onchocerca volvulus 0.0047 0.0674 0.1108
Echinococcus granulosus intermediate filament protein 0.0026 0.025 0.0111
Loa Loa (eye worm) hypothetical protein 0.0024 0.0203 0.0458
Schistosoma mansoni ets-related 0.0223 0.4314 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.1034 0.7422
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0529 0.0769
Trypanosoma brucei Aminopeptidase M1, putative 0.0068 0.1107 0.8081
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0534 0.0781
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0715 0.1205
Loa Loa (eye worm) hypothetical protein 0.0078 0.1322 0.2987
Mycobacterium ulcerans aminopeptidase N PepN 0.0068 0.1107 0.8081
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1054 0.207
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0517 0.0765
Onchocerca volvulus 0.0068 0.1107 0.2129
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.1322 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0534 0.1029
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0517 0.074
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0534 0.2964
Schistosoma mansoni lamin 0.0026 0.025 0.0114
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Trichomonas vaginalis esterase, putative 0.0078 0.1322 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.3122 0.6869
Loa Loa (eye worm) aminopeptidase N 0.0068 0.1107 0.2502
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.1322 0.2635
Trypanosoma brucei Aminopeptidase M1, putative 0.0068 0.1107 0.8081
Brugia malayi hypothetical protein 0.0024 0.0203 0.0455
Onchocerca volvulus 0.0078 0.1322 0.2635
Loa Loa (eye worm) hypothetical protein 0.0206 0.3962 0.8951
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0517 0.074
Treponema pallidum exodeoxyribonuclease (exoA) 0.004 0.0534 0.5
Mycobacterium leprae conserved hypothetical protein 0.0078 0.1322 0.5
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.025 0.0564
Schistosoma mansoni ap endonuclease 0.004 0.0534 0.0807
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.1322 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0534 0.2964
Loa Loa (eye worm) hypothetical protein 0.0078 0.1322 0.2987
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0517 0.2807
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0068 0.1107 0.8081
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0068 0.1107 0.2129
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.1322 0.0832
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0591 0.3473
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0529 0.2919
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Echinococcus multilocularis lamin dm0 0.0026 0.025 0.0111
Schistosoma mansoni gabp alpha 0.0074 0.1228 0.2494
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0469 0.2376
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.1034 0.2022
Loa Loa (eye worm) hypothetical protein 0.0063 0.1008 0.2277
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0517 0.2807
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.1322 0.0832
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0534 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0715 0.1245
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Schistosoma mansoni alpha glucosidase 0.0037 0.0469 0.0647
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0068 0.1107 0.2201
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0517 0.2807
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0517 0.074
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.1322 1
Trichomonas vaginalis chromobox protein, putative 0.0071 0.117 0.8642
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0469 0.1053
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0469 0.0626
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0715 0.1614
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0534 0.0781
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0044 0.0617 0.3699
Loa Loa (eye worm) TAR-binding protein 0.0065 0.1054 0.2381
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.1034 0.1955
Schistosoma mansoni hypothetical protein 0.0038 0.0501 0.0725
Brugia malayi beta-lactamase 0.0078 0.1322 0.297
Brugia malayi beta-lactamase family protein 0.0078 0.1322 0.297
Brugia malayi MH2 domain containing protein 0.0123 0.2241 0.5033
Loa Loa (eye worm) hypothetical protein 0.0078 0.1322 0.2987
Trypanosoma brucei glucosidase, putative 0.0037 0.0469 0.2376
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.2241 0.5062
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0469 0.2376
Onchocerca volvulus 0.023 0.4453 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0044 0.0617 0.0975
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0024 0.0203 0.0458
Echinococcus granulosus chromobox protein 1 0.0071 0.117 0.2277
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0068 0.1107 0.8081
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0469 0.2376
Trypanosoma cruzi aminopeptidase, putative 0.0068 0.1107 0.8081
Loa Loa (eye worm) hypothetical protein 0.0039 0.0517 0.1168
Brugia malayi Ets-domain containing protein 0.0074 0.1228 0.2757
Toxoplasma gondii ABC1 family protein 0.0078 0.1322 1
Echinococcus granulosus tar DNA binding protein 0.0065 0.1054 0.2003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0517 0.074
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0469 0.2376
Loa Loa (eye worm) hypothetical protein 0.0044 0.0617 0.1394
Schistosoma mansoni tar DNA-binding protein 0.0065 0.1054 0.207
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0291 0.0787
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.1228 0.2774
Mycobacterium tuberculosis Conserved protein 0.0078 0.1322 0.0832
Loa Loa (eye worm) hypothetical protein 0.0031 0.0353 0.0797
Loa Loa (eye worm) RNA binding protein 0.0065 0.1054 0.2381
Schistosoma mansoni hypothetical protein 0.0047 0.0674 0.1146
Trypanosoma cruzi Aminopeptidase M1, putative 0.0068 0.1107 0.8081
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0501 0.0725
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0534 0.2964
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0469 0.1059
Brugia malayi RNA binding protein 0.0065 0.1054 0.2367
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.1322 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0068 0.1107 0.2129
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0534 0.2964
Echinococcus multilocularis lamin 0.0026 0.025 0.0111
Echinococcus multilocularis chromobox protein 1 0.0071 0.117 0.2277
Echinococcus granulosus chromobox protein 1 0.0071 0.117 0.2277
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0534 0.1207
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.1322 0.0832
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.1034 0.7422
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.1322 1
Schistosoma mansoni alpha-glucosidase 0.0142 0.2647 0.5946
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.3122 0.7053
Onchocerca volvulus 0.0031 0.0353 0.0353
Brugia malayi Fli-1 protein 0.0223 0.4314 0.9688
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0517 0.1161
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.1034 0.7422
Entamoeba histolytica aminopeptidase, putative 0.0068 0.1107 1
Onchocerca volvulus 0.0096 0.1684 0.3486
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0517 0.0765
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0591 0.3473
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0591 0.0915
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0469 0.0626
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.1322 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0534 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0517 0.2807
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0501 0.0701

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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