Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | transcription factor Dp 1 | 0.0041 | 0.0274 | 0.0415 |
Leishmania major | hypothetical protein, conserved | 0.0014 | 0.0037 | 0.0093 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0053 | 0.0378 | 0.0573 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0092 | 0.0127 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.0483 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0039 | 0.0501 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0014 | 0.0037 | 0.0093 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0092 | 0.0092 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0053 | 0.0378 | 0.0573 |
Brugia malayi | nuclear hormone receptor | 0.0009 | 0.0001 | 0.0001 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0317 | 0.2672 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0092 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0061 | 0.0092 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.002 | 0.0089 | 0.0118 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0065 | 0.0483 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0438 | 0.372 | 0.499 |
Brugia malayi | hypothetical protein | 0.0011 | 0.001 | 0.0014 |
Brugia malayi | intermediate filament protein | 0.003 | 0.0179 | 0.0247 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0051 | 0.0362 | 0.055 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0092 | 0.1184 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0099 | 0.0777 | 0.2874 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0065 | 0.0832 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0201 | 0.0304 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0483 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Leishmania major | ATP-binding cassette protein subfamily G, member 6, putative | 0.002 | 0.0089 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0438 | 0.372 | 0.565 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0058 | 0.008 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0058 | 0.0741 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0001 | 0.0001 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.0179 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0014 | 0.0044 | 0.0059 |
Onchocerca volvulus | 0.0055 | 0.0396 | 0.0396 | |
Brugia malayi | MAP kinase sur-1 | 0.0099 | 0.0777 | 0.1072 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0014 | 0.0037 | 0.0093 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 0.0483 | 0.0647 |
Plasmodium falciparum | ABC transporter G family member 2 | 0.002 | 0.0089 | 0.0197 |
Echinococcus granulosus | tumor protein p63 | 0.0376 | 0.3182 | 0.4833 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0065 | 0.0098 |
Brugia malayi | jmjC domain containing protein | 0.0014 | 0.0037 | 0.0051 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0092 | 0.014 |
Trypanosoma brucei | ABC transporter, putative | 0.002 | 0.0089 | 0.0288 |
Brugia malayi | nuclear receptor NHR-67 | 0.0009 | 0.0001 | 0.0001 |
Echinococcus granulosus | dnaJ subfamily B | 0.0438 | 0.372 | 0.565 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0092 | 0.0127 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0185 | 0.0256 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0011 | 0.001 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0092 | 0.0127 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0009 | 0.0001 | 0.0001 |
Giardia lamblia | Telomerase catalytic subunit | 0.0317 | 0.2672 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0092 | 0.0127 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0055 | 0.0396 | 0.0601 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0092 | 0.014 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0065 | 0.0087 |
Onchocerca volvulus | 0.003 | 0.0179 | 0.0178 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0011 | 0.001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0092 | 0.0127 |
Schistosoma mansoni | protein phosphatase 2C | 0.0014 | 0.0037 | 0.0055 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0038 | 0.0244 | 0.3143 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0483 | 1 |
Schistosoma mansoni | phd/f-box containing protein | 0.0014 | 0.0037 | 0.0055 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0092 | 0.0123 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0201 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0037 | 0.0469 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0071 | 0.0532 | 1 |
Trypanosoma cruzi | ATP-binding cassette protein, putative | 0.002 | 0.0089 | 0.0288 |
Echinococcus multilocularis | musashi | 0.003 | 0.0179 | 0.0239 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0099 | 0.0777 | 0.2874 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.001 | 0.0014 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0099 | 0.0777 | 0.1041 |
Echinococcus multilocularis | tumor protein p63 | 0.0376 | 0.3182 | 0.4268 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.001 | 0.0014 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0092 | 0.014 |
Trypanosoma brucei | cytochrome P450, putative | 0.0038 | 0.0244 | 0.0873 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0317 | 0.2672 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0099 | 0.0777 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0065 | 0.0087 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0038 | 0.0244 | 0.4934 |
Echinococcus multilocularis | 0.0011 | 0.0012 | 0.0016 | |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.002 | 0.0089 | 0.0118 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0014 | 0.0037 | 0.0469 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0071 | 0.0532 | 0.0807 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.0179 | 0.2298 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0011 | 0.0012 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0065 | 0.0832 |
Schistosoma mansoni | jumonji domain containing protein | 0.0051 | 0.0362 | 0.055 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0127 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0014 | 0.0037 | 0.0055 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0382 | 0.0527 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0065 | 0.0098 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0092 | 0.014 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.0179 | 0.0271 |
Brugia malayi | nuclear receptor RXR | 0.0009 | 0.0001 | 0.0001 |
Brugia malayi | jmjC domain containing protein | 0.0014 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0092 | 0.1184 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0092 | 0.0123 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0099 | 0.0777 | 0.5 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.002 | 0.0089 | 0.0134 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0099 | 0.0777 | 0.1179 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0001 | 0.0001 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.002 | 0.0089 | 0.0118 |
Brugia malayi | Cytochrome P450 family protein | 0.0038 | 0.0244 | 0.0337 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 0.0483 | 0.1769 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0065 | 0.0098 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0065 | 0.0098 |
Leishmania major | cytochrome p450-like protein | 0.0038 | 0.0244 | 0.0873 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0869 | 0.7454 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0051 | 0.0362 | 0.0486 |
Brugia malayi | Telomerase reverse transcriptase | 0.0845 | 0.7246 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0127 |
Schistosoma mansoni | jumonji domain containing protein | 0.0014 | 0.0037 | 0.0055 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0092 | 0.0127 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0092 | 0.0123 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0092 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0012 | 0.0017 |
Brugia malayi | jmjC domain containing protein | 0.0014 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0127 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0092 | 0.1184 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.002 | 0.0089 | 0.1625 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0037 | 0.0469 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0235 | 0.0325 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0092 | 0.0127 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0092 | 0.0127 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0065 | 0.0098 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0065 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0127 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0014 | 0.0037 | 0.0055 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0092 | 0.014 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0071 | 0.0532 | 0.1954 |
Onchocerca volvulus | 0.003 | 0.0179 | 0.0178 | |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0065 | 0.0098 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0092 | 0.0123 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.002 | 0.0089 | 0.1625 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0012 | 0.0017 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0485 | 0.0735 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0317 | 0.2672 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0099 | 0.0777 | 0.1041 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0179 | 0.2298 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0382 | 0.4912 |
Brugia malayi | jmjC domain containing protein | 0.0014 | 0.0037 | 0.0051 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0185 | 0.2382 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0015 | 0.0052 | 0.0069 |
Brugia malayi | jmjC domain containing protein | 0.0051 | 0.0362 | 0.05 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0012 | 0.0018 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0092 | 0.0092 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0092 | 0.0127 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0065 | 0.009 |
Brugia malayi | ABC transporter family protein | 0.0017 | 0.0063 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0039 | 0.0501 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0092 | 0.0123 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0099 | 0.0777 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0009 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0011 | 0.001 | 0.0127 |
Brugia malayi | tailless protein | 0.0009 | 0.0001 | 0.0001 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0014 | 0.0037 | 0.0049 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0382 | 0.0527 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0071 | 0.0532 | 0.1954 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0014 | 0.0037 | 0.0469 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0099 | 0.0777 | 0.2874 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0092 | 0.014 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0065 | 0.0483 | 0.0733 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0092 | 0.014 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0235 | 0.0357 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0396 | 0.5097 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.001 | 0.0015 |
Schistosoma mansoni | lamin | 0.003 | 0.0179 | 0.0271 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0051 | 0.0362 | 0.0486 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0071 | 0.0532 | 0.1954 |
Onchocerca volvulus | 0.0031 | 0.0185 | 0.0185 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0053 | 0.0378 | 0.4859 |
Echinococcus multilocularis | phd:f box containing protein | 0.0014 | 0.0037 | 0.0049 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0071 | 0.0532 | 0.0807 |
Brugia malayi | hypothetical protein | 0.0011 | 0.001 | 0.0014 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0009 | 0.0001 | 0.0001 |
Schistosoma mansoni | cytochrome P450 | 0.0011 | 0.0012 | 0.0018 |
Brugia malayi | cytochrome P450 | 0.0011 | 0.0012 | 0.0017 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0382 | 0.4912 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.0179 | 0.2298 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0092 | 0.014 |
Brugia malayi | nuclear receptor NHR-88 | 0.0009 | 0.0001 | 0.0001 |
Echinococcus granulosus | lamin | 0.003 | 0.0179 | 0.0271 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0071 | 0.0532 | 0.0734 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0092 | 0.1184 |
Onchocerca volvulus | 0.002 | 0.0092 | 0.0092 | |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0014 | 0.0037 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0037 | 0.0469 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0092 | 0.014 |
Echinococcus granulosus | phd:f box containing protein | 0.0014 | 0.0037 | 0.0055 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0009 | 0.0001 | 0.0001 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0014 | 0.0037 | 0.0093 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0099 | 0.0777 | 0.2874 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0092 | 0.0127 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0185 | 0.0281 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0768 | 0.6583 | 0.883 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0099 | 0.0777 | 0.5 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0092 | 0.1184 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0014 | 0.0044 | 0.0066 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0065 | 0.0087 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0317 | 0.2672 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0038 | 0.0244 | 0.0873 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0099 | 0.0777 | 0.1179 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0014 | 0.0037 | 0.0055 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0011 | 0.001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0092 | 0.0127 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0071 | 0.0532 | 0.0713 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.0483 | 0.0733 |
Schistosoma mansoni | lamin | 0.003 | 0.0179 | 0.0271 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0038 | 0.0244 | 0.3143 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0053 | 0.0378 | 0.0573 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0092 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0092 | 0.1184 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0092 | 0.014 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.002 | 0.0089 | 0.0134 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0014 | 0.0037 | 0.0469 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.001 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0092 | 0.0127 |
Trypanosoma brucei | ATP-binding cassette protein, putative | 0.002 | 0.0089 | 0.0288 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0092 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0174 | 0.2237 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0092 | 0.0092 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0317 | 0.2672 | 1 |
Echinococcus multilocularis | lamin | 0.003 | 0.0179 | 0.0239 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0041 | 0.0274 | 0.0366 |
Schistosoma mansoni | ABC transporter | 0.0017 | 0.0063 | 0.0095 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0092 | 0.014 |
Plasmodium vivax | ABC transporter G family member 2, putative | 0.002 | 0.0089 | 0.0197 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0038 | 0.0244 | 0.0873 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0092 | 0.0127 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.002 | 0.0089 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0235 | 0.3023 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0012 | 0.0151 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0071 | 0.0532 | 0.1954 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.002 | 0.0089 | 0.0134 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0092 | 0.014 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0424 | 0.1548 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0092 | 0.014 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0012 | 0.0151 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0099 | 0.0777 | 0.2874 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0009 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0092 | 0.1184 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.0179 | 0.0271 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0001 | 0.0007 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0038 | 0.0244 | 0.3143 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0014 | 0.0037 | 0.0093 |
Mycobacterium tuberculosis | Probable conserved transmembrane ATP-binding protein ABC transporter | 0.0016 | 0.0061 | 0.1033 |
Trypanosoma cruzi | ABC transporter, putative | 0.002 | 0.0089 | 0.0288 |
Mycobacterium leprae | putative cytochrome p450 | 0.0011 | 0.0012 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0092 | 0.0127 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0099 | 0.0777 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0092 | 0.0127 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0317 | 0.2672 | 1 |
Loa Loa (eye worm) | ABC transporter | 0.0017 | 0.0063 | 0.0803 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0092 | 0.014 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0099 | 0.0777 | 0.2874 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0201 | 0.0304 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0071 | 0.0532 | 0.6847 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0099 | 0.0777 | 0.2668 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0127 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0009 | 0.0001 | 0.0001 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.0179 | 0.0271 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0092 | 0.0127 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.0179 | 0.0239 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0099 | 0.0777 | 0.2874 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0768 | 0.6583 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0092 | 0.1184 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0014 | 0.0037 | 0.0055 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0768 | 0.6583 | 1 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0014 | 0.0037 | 0.0055 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0092 | 0.0127 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0092 | 0.0123 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0092 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0151 | 0.1934 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0065 | 0.0098 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0092 | 0.014 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0317 | 0.2672 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 0.0483 | 0.1769 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0001 | 0.0001 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0092 | 0.0123 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0015 | 0.0052 | 0.0078 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.0483 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0044 | 0.0562 |
Brugia malayi | Cytochrome P450 family protein | 0.0038 | 0.0244 | 0.0337 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0099 | 0.0777 | 0.2874 |
Brugia malayi | jmjC domain containing protein | 0.0053 | 0.0378 | 0.0521 |
Trypanosoma brucei | protein kinase, putative | 0.0099 | 0.0777 | 0.2874 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0014 | 0.0037 | 0.0049 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0012 | 0.0018 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0014 | 0.0037 | 0.0093 |
Brugia malayi | conserved hypotetical protein | 0.0009 | 0.0001 | 0.0001 |
Leishmania major | ATP-binding cassette protein subfamily G, member 4, putative | 0.002 | 0.0089 | 0.0288 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0099 | 0.0777 | 0.1179 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0092 | 0.1184 |
Brugia malayi | ecdysone receptor | 0.0009 | 0.0001 | 0.0001 |
Toxoplasma gondii | ATP-binding cassette G family transporter ABCG84 | 0.002 | 0.0089 | 0.0288 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.002 | 0.0089 | 0.1625 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0092 | 0.014 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0201 | 0.0304 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 0.0428 mg/ml | Cytotoxicity against Homo sapiens (human) MCF-7 cells assessed as survival after 48 hr by MTT assay | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.