TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 319.379 | Formula: C15H17N3O3S
H donors: 2 H acceptors: 4 LogP: 2.16 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: Oc1ccn(c(=O)c1)c1nc(c(s1)C(=O)NCCC1CC1)C
InChi: 1S/C15H17N3O3S/c1-9-13(14(21)16-6-4-10-2-3-10)22-15(17-9)18-7-5-11(19)8-12(18)20/h5,7-8,10,19H,2-4,6H2,1H3,(H,16,21)
InChiKey: DIIHHZJGTKSBTH-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Mus musculus	stearoyl-Coenzyme A desaturase 1	Starlite/ChEMBL	References
Homo sapiens	stearoyl-CoA desaturase (delta-9-desaturase)	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Leishmania donovani	stearic acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania major	stearic acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Plasmodium knowlesi	stearoyl-CoA desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania mexicana	stearic acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Trypanosoma cruzi	fatty acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Trypanosoma cruzi	fatty acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania braziliensis	stearic acid desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania infantum	stearic acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Loa Loa (eye worm)	acyl-CoA desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania infantum	fatty-acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Candida albicans	one of two potential fatty acid desaturase genes similar to S. cerevisiae OLE1 (YGL055W) delta-9-fatty acid desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania braziliensis	fatty-acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Candida albicans	one of two potential fatty acid desaturase genes similar to S. cerevisiae OLE1 (YGL055W) delta-9-fatty acid desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Plasmodium vivax	stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative	Get druggable targets OG5_126939	All targets in OG5_126939
Plasmodium falciparum	stearoyl-CoA desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania donovani	fatty-acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Trypanosoma brucei gambiense	fatty acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania mexicana	fatty-acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Brugia malayi	acyl-CoA desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Onchocerca volvulus		Get druggable targets OG5_126939	All targets in OG5_126939
Trypanosoma brucei	fatty acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Trypanosoma cruzi	fatty acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Plasmodium berghei	stearoyl-CoA desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Plasmodium yoelii	delta-9 fatty acid desaturase	Get druggable targets OG5_126939	All targets in OG5_126939
Onchocerca volvulus		Get druggable targets OG5_126939	All targets in OG5_126939
Neospora caninum	fatty acyl-CoA desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Trypanosoma congolense	fatty acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939
Leishmania major	fatty-acid desaturase, putative	Get druggable targets OG5_126939	All targets in OG5_126939

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Plasmodium vivax	stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative	0.0205	0.2334	0.5769
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0338	0.4005	0.4507
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	TK/ABL protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Trichomonas vaginalis	AGC family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0022	0.0055	0.0055
Mycobacterium leprae	conserved hypothetical protein	0.0079	0.0756	0.5
Schistosoma mansoni	tyrosine protein kinase	0.0338	0.4005	0.4507
Brugia malayi	steroid hormone receptor	0.0022	0.0055	0.0055
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	hypothetical protein	0.0076	0.0721	0.0721
Echinococcus multilocularis	activated cdc42 kinase 1	0.0338	0.4005	0.4005
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0022	0.0055	0.0055
Echinococcus multilocularis	tyrosine protein kinase shark	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	penicillin-binding protein, putative	0.0079	0.0756	0.1776
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0338	0.4005	0.4005
Leishmania major	hypothetical protein, conserved	0.0079	0.0756	0.1888
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	cysteine surface protein, putative	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Echinococcus granulosus	activated cdc42 kinase 1	0.0338	0.4005	0.4005
Brugia malayi	Latrophilin receptor protein 2	0.0035	0.0213	0.0213
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0338	0.4005	0.4507
Schistosoma mansoni	survival motor neuron protein	0.0167	0.186	0.2094
Onchocerca volvulus		0.0079	0.0756	0.1888
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0338	0.4005	1
Schistosoma mansoni	hypothetical protein	0.0035	0.0213	0.024
Trypanosoma cruzi	fatty acid desaturase, putative	0.0205	0.2334	0.5827
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0022	0.0055	0.0055
Schistosoma mansoni	hypothetical protein	0.0035	0.0213	0.024
Loa Loa (eye worm)	TK/ROR protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0338	0.4005	0.4005
Trypanosoma brucei	protein kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	FTZ F1 alpha	0.0022	0.0055	0.0055
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0338	0.4005	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0338	0.4005	0.4005
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0022	0.0055	0.0055
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0022	0.0055	0.0055
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0025	0.0083	0.0072
Brugia malayi	Guanylyl cyclase protein 23	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0079	0.0756	0.0851
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0022	0.0055	0.0055
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0052	0.0419	0.0419
Loa Loa (eye worm)	TK/ACK protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Schistosoma mansoni	importin beta-1	0.003	0.0155	0.0175
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Echinococcus multilocularis	ecdysone induced protein 78C	0.0022	0.0055	0.0055
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0035	0.0213	0.0213
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Onchocerca volvulus	Tyrosine kinase homolog	0.0338	0.4005	1
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0338	0.4005	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0022	0.0055	0.0055
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Echinococcus multilocularis	integrin linked protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	STE family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Tyrosine-protein kinase abl-1	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	tyrosin kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase HCK	0.0338	0.4005	0.4005
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0338	0.4005	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus granulosus	protein tyrosine kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0022	0.0055	0.0055
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0338	0.4005	1
Mycobacterium tuberculosis	Probable lipase LipD	0.0079	0.0756	0.1251
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0022	0.0055	0.0055
Entamoeba histolytica	hypothetical protein, conserved	0.0338	0.4005	1
Echinococcus granulosus	ephrin type A receptor 4 A	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	epidermal growth factor receptor	0.0338	0.4005	0.4005
Brugia malayi	hypothetical protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Onchocerca volvulus		0.0079	0.0756	0.1888
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0079	0.0756	0.1251
Trichomonas vaginalis	D-aminoacylase, putative	0.0079	0.0756	0.1776
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Schistosoma mansoni	transcription factor LCR-F1	0.0077	0.074	0.0833
Onchocerca volvulus		0.0031	0.0168	0.0419
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0338	0.4005	0.4005
Echinococcus granulosus	receptor type guanylyl cyclase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Echinococcus multilocularis	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Echinococcus granulosus	epidermal growth factor receptor	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Echinococcus multilocularis	protein tyrosine kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0756	0.0756
Plasmodium falciparum	tyrosine kinase-like protein	0.0338	0.4005	1
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0756	0.0756
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Entamoeba histolytica	tyrosin kinase, putative	0.0338	0.4005	1
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0022	0.0055	0.0055
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0025	0.0083	0.0072
Echinococcus multilocularis	protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	protein kinase atn1, putative	0.0338	0.4005	1
Brugia malayi	Steroid receptor seven-up type 2	0.0022	0.0055	0.0055
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0022	0.0055	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0338	0.4005	0.4005
Brugia malayi	SH2 domain containing protein	0.0338	0.4005	0.4005
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0022	0.0055	0.0055
Toxoplasma gondii	STE kinase	0.0338	0.4005	1
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Mycobacterium tuberculosis	Probable hydrolase	0.0079	0.0756	0.1251
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0338	0.4005	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0338	0.4005	0.4005
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0338	0.4005	0.4005
Schistosoma mansoni	lamin	0.0031	0.0168	0.0189
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Giardia lamblia	Kinase	0.0338	0.4005	1
Brugia malayi	nuclear hormone receptor	0.0022	0.0055	0.0055
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Trichomonas vaginalis	CAMK family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0338	0.4005	0.4005
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0338	0.4005	0.4005
Echinococcus granulosus	raf serine:threonine protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	beta-lactamase	0.0079	0.0756	0.0756
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0025	0.0083	0.0208
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Onchocerca volvulus	Bile acid receptor homolog	0.0022	0.0055	0.0138
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0079	0.0756	0.0756
Echinococcus granulosus	activated cdc42 kinase 1	0.0338	0.4005	0.4005
Brugia malayi	hypothetical protein	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Brugia malayi	ecdysteroid receptor	0.0022	0.0055	0.0055
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	hypothetical protein	0.0035	0.0213	0.024
Echinococcus multilocularis	microtubule associated protein 2	0.0729	0.8886	0.8886
Loa Loa (eye worm)	TK/RYK protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0052	0.0419	0.0472
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0022	0.0055	0.0062
Echinococcus granulosus	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Schistosoma mansoni	serine/threonine protein kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Echinococcus multilocularis	tyrosine kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	kinase suppressor of Ras 1	0.0338	0.4005	0.4005
Echinococcus multilocularis	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Entamoeba histolytica	hypothetical protein	0.0077	0.074	0.1735
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0223	0.2559	0.639
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	serine/threonine protein kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	serine/threonine kinase, putative	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trypanosoma cruzi	protein kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	intermediate filament protein	0.0031	0.0168	0.0168
Plasmodium falciparum	protein kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	GPCR, family 2	0.0035	0.0213	0.0213
Giardia lamblia	Kinase, NEK	0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	TK/INSR protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0022	0.0055	0.0055
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0022	0.0055	0.0055
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Schistosoma mansoni	serine/threonine RGC	0.0338	0.4005	0.4507
Brugia malayi	acyl-CoA desaturase	0.0205	0.2334	0.2334
Leishmania major	hypothetical protein, conserved	0.0338	0.4005	1
Brugia malayi	SH2 domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0338	0.4005	0.4005
Brugia malayi	photoreceptor-specific nuclear receptor	0.0022	0.0055	0.0055
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0022	0.0055	0.0055
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0035	0.0213	0.0213
Echinococcus granulosus	c src tyrosine kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0022	0.0055	0.0055
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0338	0.4005	0.4005
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Trypanosoma brucei	fatty acid desaturase, putative	0.0223	0.2559	0.639
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0079	0.0756	0.1251
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Onchocerca volvulus		0.0031	0.0168	0.0419
Brugia malayi	nuclear receptor NHR-88	0.0022	0.0055	0.0055
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/EPH protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0338	0.4005	0.4507
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0338	0.4005	1
Brugia malayi	hypothetical protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.003	0.0155	0.0155
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Schistosoma mansoni	retinoic acid receptor RXR	0.0022	0.0055	0.0062
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Mycobacterium tuberculosis	Conserved protein	0.0079	0.0756	0.1251
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0338	0.4005	0.4005
Echinococcus granulosus	intermediate filament protein	0.0031	0.0168	0.0168
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Brugia malayi	C-terminal src kinase protein 1	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0338	0.4005	1
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Brugia malayi	RNA, U transporter 1	0.0087	0.0857	0.0857
Echinococcus granulosus	microtubule associated protein 2	0.0729	0.8886	0.8886
Onchocerca volvulus	Protein ultraspiracle homolog	0.0022	0.0055	0.0138
Trichomonas vaginalis	importin beta-1, putative	0.0025	0.0083	0.0072
Loa Loa (eye worm)	TK/ALK protein kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0338	0.4005	0.4005
Trypanosoma brucei	importin beta-1 subunit, putative	0.003	0.0155	0.0388
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase Blk	0.0338	0.4005	0.4005
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0022	0.0055	0.0055
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0167	0.186	0.186
Entamoeba histolytica	hypothetical protein	0.0077	0.074	0.1735
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus multilocularis	musashi	0.0031	0.0168	0.0168
Echinococcus granulosus	protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0035	0.0213	0.0213
Loa Loa (eye worm)	TK/Met protein kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	epidermal growth factor receptor	0.0338	0.4005	0.4005
Brugia malayi	Receptor family ligand binding region containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Schistosoma mansoni	RAR-like nuclear receptor	0.0022	0.0055	0.0062
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0338	0.4005	0.4005
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	tyrosin kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0035	0.0213	0.0213
Echinococcus multilocularis	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0338	0.4005	0.4005
Echinococcus multilocularis	heat shock protein 70	0.0338	0.4005	0.4005
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0022	0.0055	0.0062
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0338	0.4005	0.4005
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0338	0.4005	0.4005
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	hypothetical protein	0.0076	0.0721	0.0812
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	steroid hormone receptor	0.0022	0.0055	0.0055
Echinococcus multilocularis	FTZ F1 alpha	0.0022	0.0055	0.0055
Entamoeba histolytica	serine/threonine kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Echinococcus multilocularis	activin receptor type	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0338	0.4005	0.4507
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0077	0.074	0.074
Echinococcus granulosus	insulin receptor	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Mycobacterium leprae	Probable lipase LipE	0.0079	0.0756	0.5
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0022	0.0055	0.0062
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0022	0.0055	0.0055
Echinococcus multilocularis	c src tyrosine kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	ankyrin repeat protein	0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0052	0.0419	0.0472
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Plasmodium vivax	hypothetical protein, conserved	0.0079	0.0756	0.1776
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	tyrosine kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	transfer RNA-Thr	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0338	0.4005	1
Schistosoma mansoni	ran	0.0022	0.0055	0.0062
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	coup transcription factor	0.0022	0.0055	0.0062
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0022	0.0055	0.0055
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0035	0.0213	0.0213
Mycobacterium ulcerans	lipase LipD	0.0079	0.0756	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0756	0.0756
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0502	0.6046	1
Onchocerca volvulus		0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0052	0.0419	0.0419
Echinococcus granulosus	beta LACTamase domain containing family member	0.0079	0.0756	0.0756
Echinococcus granulosus	lamin	0.0031	0.0168	0.0168
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0079	0.0756	0.1776
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Echinococcus granulosus	GPCR family 2	0.0035	0.0213	0.0213
Toxoplasma gondii	ABC1 family protein	0.0079	0.0756	0.1888
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	microtubule-associated protein tau	0.0729	0.8886	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0022	0.0055	0.0055
Loa Loa (eye worm)	acyl-CoA desaturase	0.0205	0.2334	0.2334
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0052	0.0419	0.0419
Entamoeba histolytica	receptor protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Schistosoma mansoni	hypothetical protein	0.0167	0.186	0.2094
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0338	0.4005	0.4005
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0077	0.074	0.1735
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0022	0.0055	0.0062
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	serine/threonine protein kinase	0.0338	0.4005	0.4507
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0022	0.0055	0.0055
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0338	0.4005	1
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0022	0.0055	0.0055
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Trichomonas vaginalis	esterase, putative	0.0079	0.0756	0.1776
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0338	0.4005	0.4005
Schistosoma mansoni	ephrin receptor	0.0338	0.4005	0.4507
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	ankyrin repeat protein	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0338	0.4005	0.4005
Entamoeba histolytica	serine/threonine kinase, putative	0.0338	0.4005	1
Brugia malayi	Furin-like cysteine rich region family protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Echinococcus multilocularis	snurportin 1	0.0325	0.3839	0.3839
Loa Loa (eye worm)	TK/DDR protein kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0338	0.4005	0.4005
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0022	0.0055	0.0055
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Echinococcus multilocularis	epidermal growth factor receptor	0.0338	0.4005	0.4005
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0111	0.116	0.116
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0022	0.0055	0.0055
Echinococcus granulosus	tyrosine kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0022	0.0055	0.0055
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Onchocerca volvulus		0.0223	0.2559	0.639
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus granulosus	tyrosine kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0338	0.4005	0.4005
Schistosoma mansoni	ran	0.0022	0.0055	0.0062
Brugia malayi	Importin beta-1 subunit	0.003	0.0155	0.0155
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0338	0.4005	0.4005
Plasmodium falciparum	protein kinase, putative	0.0338	0.4005	1
Schistosoma mansoni	intermediate filament proteins	0.0031	0.0168	0.0189
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0338	0.4005	0.4005
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0338	0.4005	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	survival motor neuron protein 1	0.0818	1	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0079	0.0756	0.1776
Onchocerca volvulus		0.0338	0.4005	1
Echinococcus multilocularis	survival motor neuron protein 1	0.0818	1	1
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0079	0.0756	0.1888
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0338	0.4005	0.4005
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Schistosoma mansoni	hypothetical protein	0.0035	0.0213	0.024
Plasmodium falciparum	stearoyl-CoA desaturase	0.0205	0.2334	0.5769
Entamoeba histolytica	hypothetical protein	0.0025	0.0083	0.0072
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0031	0.0168	0.0168
Leishmania major	protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0338	0.4005	1
Plasmodium vivax	protein kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	integrin linked protein kinase	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0338	0.4005	1
Mycobacterium tuberculosis	Conserved protein	0.0079	0.0756	0.1251
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0035	0.0213	0.0213
Plasmodium falciparum	importin beta, putative	0.003	0.0155	0.0254
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Leishmania major	GTP-binding protein, putative	0.0022	0.0055	0.0137
Trichomonas vaginalis	penicillin-binding protein, putative	0.0079	0.0756	0.1776
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0338	0.4005	1
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Schistosoma mansoni	lamin	0.0031	0.0168	0.0189
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0338	0.4005	0.4005
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0022	0.0055	0.0138
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Toxoplasma gondii	HEAT repeat-containing protein	0.003	0.0155	0.0388
Giardia lamblia	Kinase, NEK	0.0338	0.4005	1
Schistosoma mansoni	hypothetical protein	0.0077	0.074	0.0833
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0022	0.0055	0.0055
Echinococcus granulosus	activin receptor type	0.0338	0.4005	0.4005
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0111	0.116	0.116
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0022	0.0055	0.0055
Leishmania major	fatty-acid desaturase, putative	0.0223	0.2559	0.639
Schistosoma mansoni	hypothetical protein	0.0325	0.3839	0.432
Loa Loa (eye worm)	TK/CSK protein kinase	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0338	0.4005	1
Brugia malayi	ephrin receptor 1 precursor	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	conserved hypothetical protein	0.0338	0.4005	1
Echinococcus granulosus	natriuretic peptide receptor 1	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0338	0.4005	0.4507
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Schistosoma mansoni	thyroid hormone receptor	0.0022	0.0055	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0022	0.0055	0.0055
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0338	0.4005	1
Brugia malayi	Intermediate filament tail domain containing protein	0.0031	0.0168	0.0168
Plasmodium falciparum	protein kinase, putative	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0756	0.0756
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0338	0.4005	0.4005
Entamoeba histolytica	hypothetical protein	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase pr2	0.0338	0.4005	0.4005
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Echinococcus multilocularis	lamin	0.0031	0.0168	0.0168
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Trypanosoma cruzi	hypothetical protein, conserved	0.0079	0.0756	0.1888
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0338	0.4005	0.4005
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0052	0.0419	0.0419
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0111	0.116	0.116
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0338	0.4005	1
Schistosoma mansoni	ephrin receptor	0.0338	0.4005	0.4507
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0079	0.0756	0.0851
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Trypanosoma brucei	Pseudokinase, putative	0.0338	0.4005	1
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0022	0.0055	0.0137
Onchocerca volvulus		0.0022	0.0055	0.0138
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0338	0.4005	0.4005
Mycobacterium tuberculosis	Probable esterase LipL	0.0079	0.0756	0.1251
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0338	0.4005	0.4005
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0079	0.0756	0.0756
Echinococcus multilocularis	tyrosine protein kinase csk	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0168	0.0168
Brugia malayi	protein-tyrosine kinase	0.0338	0.4005	0.4005
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Echinococcus multilocularis	insulin receptor	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0022	0.0055	0.0055
Plasmodium vivax	importin-beta 2, putative	0.003	0.0155	0.0254
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0213	0.0213
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0338	0.4005	0.4005
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0052	0.0419	0.0419
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0022	0.0055	0.0062
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Onchocerca volvulus		0.0167	0.186	0.4645
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0022	0.0055	0.0055
Brugia malayi	Nuclear hormone receptor-like 1	0.0022	0.0055	0.0055
Entamoeba histolytica	tyrosin kinase, putative	0.0338	0.4005	1
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0022	0.0055	0.0137
Onchocerca volvulus		0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Brugia malayi	Tyrosine-protein kinase PR2	0.0338	0.4005	0.4005
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0022	0.0055	0.0062
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	hypothetical protein	0.0338	0.4005	0.4507
Echinococcus multilocularis	protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0338	0.4005	0.4005
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0022	0.0055	0.0055
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0338	0.4005	0.4507
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Toxoplasma gondii	protein kinase domain-containing protein	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Trypanosoma cruzi	protein kinase, putative	0.0338	0.4005	1
Trypanosoma brucei	hypothetical protein, conserved	0.0079	0.0756	0.1888
Trypanosoma cruzi	fatty acid desaturase, putative	0.0223	0.2559	0.639
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TK family protein kinase	0.0338	0.4005	1
Echinococcus granulosus	importin subunit beta 1	0.003	0.0155	0.0155
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0079	0.0756	0.0756
Schistosoma mansoni	serine/threonine protein kinase	0.0338	0.4005	0.4507
Echinococcus granulosus	ecdysone induced protein 78C	0.0022	0.0055	0.0055
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0338	0.4005	0.4507
Entamoeba histolytica	receptor protein kinase, putative	0.0338	0.4005	1
Schistosoma mansoni	protein tyrosine kinase	0.0338	0.4005	0.4507
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0338	0.4005	0.4005
Onchocerca volvulus		0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Giardia lamblia	Protein 21.1	0.0338	0.4005	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0079	0.0756	0.1888
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0022	0.0055	0.0055
Entamoeba histolytica	hypothetical protein	0.0077	0.074	0.1735
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0756	0.0756
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	tyrosine kinase, putative	0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus multilocularis	lamin dm0	0.0031	0.0168	0.0168
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Loa Loa (eye worm)	hypothetical protein	0.0818	1	1
Brugia malayi	integrin-linked kinase	0.0338	0.4005	0.4005
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0022	0.0055	0.0055
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0022	0.0055	0.0055
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0338	0.4005	1
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0338	0.4005	0.4005
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Onchocerca volvulus		0.0338	0.4005	1
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0077	0.074	0.074
Brugia malayi	hypothetical protein	0.0077	0.074	0.074
Echinococcus granulosus	snurportin 1	0.0325	0.3839	0.3839
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0161	0.0161
Brugia malayi	Raf kinase	0.0338	0.4005	0.4005
Brugia malayi	SRC-1	0.0338	0.4005	0.4005
Brugia malayi	latrophilin 2 splice variant baaae	0.0076	0.0721	0.0721
Mycobacterium ulcerans	esterase/lipase LipP	0.0079	0.0756	1
Mycobacterium tuberculosis	Probable lipase LipE	0.0079	0.0756	0.1251
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0022	0.0055	0.0055
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Echinococcus multilocularis	importin subunit beta 1	0.003	0.0155	0.0155
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0338	0.4005	0.4005
Schistosoma mansoni	thyroid hormone receptor	0.0022	0.0055	0.0062
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0338	0.4005	0.4005
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Brugia malayi	intermediate filament protein	0.0031	0.0168	0.0168
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase shark	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase domain containing protein	0.0338	0.4005	1
Echinococcus granulosus	tyrosine protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0338	0.4005	0.4005
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase Srms	0.0338	0.4005	0.4005
Schistosoma mansoni	nuclear hormone receptor	0.0022	0.0055	0.0062
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0338	0.4005	0.4005
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0022	0.0055	0.0055
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	serine/threonine protein kinase	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0338	0.4005	0.4005
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Leishmania major	protein kinase, putative	0.0338	0.4005	1
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Brugia malayi	Protein kinase domain containing protein	0.0338	0.4005	0.4005
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0052	0.0419	0.0419
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0022	0.0055	0.0055
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Entamoeba histolytica	serine/threonine kinase, putative	0.0338	0.4005	1
Loa Loa (eye worm)	hypothetical protein	0.0111	0.116	0.116
Echinococcus multilocularis	FL cytokine receptor	0.0338	0.4005	0.4005
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0338	0.4005	0.4005
Mycobacterium ulcerans	beta-lactamase	0.0079	0.0756	1
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0338	0.4005	1
Brugia malayi	beta-lactamase family protein	0.0079	0.0756	0.0756
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0756	0.0756
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0338	0.4005	1
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Toxoplasma gondii	protein kinase	0.0338	0.4005	1
Mycobacterium ulcerans	hypothetical protein	0.0079	0.0756	1
Loa Loa (eye worm)	SRC-1	0.0338	0.4005	0.4005
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0079	0.0756	0.1251
Leishmania major	importin beta-1 subunit, putative	0.0025	0.0083	0.0208
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0338	0.4005	0.4005
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0338	0.4005	0.4005
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0022	0.0055	0.0137
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0022	0.0055	0.0055
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0022	0.0055	0.0137
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0338	0.4005	0.4005
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0338	0.4005	0.4005
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0338	0.4005	1
Trypanosoma brucei	importin beta-1 subunit, putative	0.003	0.0155	0.0388
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0022	0.0055	0.0055
Leishmania major	stearic acid desaturase, putative	0.0223	0.2559	0.639
Loa Loa (eye worm)	TK/FAK protein kinase	0.0338	0.4005	0.4005
Brugia malayi	beta-lactamase	0.0079	0.0756	0.0756
Loa Loa (eye worm)	hypothetical protein	0.0338	0.4005	0.4005
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0055	0.0055
Schistosoma mansoni	protein kinase	0.0338	0.4005	0.4507
Schistosoma mansoni	tyrosine kinase	0.0338	0.4005	0.4507
Mycobacterium tuberculosis	Conserved protein	0.0079	0.0756	0.1251
Entamoeba histolytica	protein kinase, putative	0.0338	0.4005	1
Trypanosoma cruzi	fatty acid desaturase, putative	0.0205	0.2334	0.5827
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0338	0.4005	0.4005
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0052	0.0419	0.0472
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0079	0.0756	1
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0338	0.4005	0.4005
Brugia malayi	beta-lactamase family protein	0.0079	0.0756	0.0756
Echinococcus granulosus	lamin dm0	0.0031	0.0168	0.0168
Trichomonas vaginalis	TKL family protein kinase	0.0338	0.4005	1
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0325	0.3839	0.3839
Loa Loa (eye worm)	TK protein kinase	0.0338	0.4005	0.4005

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 69 nM	Inhibition of SCD1 in mouse liver microsomes	ChEMBL.	24370012
IC50 (binding)	= 783 nM	Inhibition of SCD1 in human HepG2 cells using radiolabeled stearic acid as substrate	ChEMBL.	24370012
Inhibition (binding)		Inhibition of human delta-5 desaturase at 10 uM	ChEMBL.	24370012
Inhibition (binding)		Inhibition of human delta-6 desaturase at 10 uM	ChEMBL.	24370012

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3104414

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1819040