Detailed information for compound 1900212

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 530.764 | Formula: C24H38N2O5S3
  • H donors: 2 H acceptors: 3 LogP: 4.06 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: CSCC[C@@H](CSSC[C@H](C(=O)NCC(=O)OC(C(C)C)OC(=O)CC)Cc1ccccc1)N
  • InChi: 1S/C24H38N2O5S3/c1-5-21(27)30-24(17(2)3)31-22(28)14-26-23(29)19(13-18-9-7-6-8-10-18)15-33-34-16-20(25)11-12-32-4/h6-10,17,19-20,24H,5,11-16,25H2,1-4H3,(H,26,29)/t19-,20+,24?/m1/s1
  • InChiKey: HLSZGLYKPAVFCU-HVUWCZLESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei PAB1-binding protein , putative 0.0042 0.0403 0.5637
Echinococcus multilocularis snurportin 1 0.0261 0.3124 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0059 0.0612 0.0925
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.031 0.3734 0.5643
Schistosoma mansoni sugar transporter 0.0027 0.0217 0.0647
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0036 0.0333 1
Echinococcus multilocularis solute carrier family 22 0.0027 0.0217 0.0647
Chlamydia trachomatis proline--tRNA ligase 0.002 0.0134 0.2978
Treponema pallidum prolyl-tRNA synthetase 0.002 0.0134 1
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0011 0.0016 0.0218
Trichomonas vaginalis Importin beta-1 subunit, putative 0.002 0.0128 0.0564
Brugia malayi nuclear hormone receptor 0.0017 0.0091 0.0334
Brugia malayi hypothetical protein 0.0027 0.0217 0.0886
Loa Loa (eye worm) hypothetical protein 0.0057 0.0589 0.1851
Onchocerca volvulus 0.0027 0.0217 0.4472
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0091 0.0334
Brugia malayi hypothetical protein 0.0027 0.0217 0.0886
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0018 0.0105 0.1468
Trypanosoma brucei glucose transporter 1E 0.006 0.0621 0.868
Echinococcus granulosus dna polymerase eta 0.0016 0.0086 0.0227
Brugia malayi Importin beta-1 subunit 0.0024 0.0185 0.0747
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0011 0.0016 0.0024
Plasmodium vivax calcium-dependent protein kinase, putative 0.0059 0.0612 0.0597
Toxoplasma gondii HEAT repeat-containing protein 0.0024 0.0185 0.028
Echinococcus granulosus importin subunit beta 1 0.0024 0.0185 0.0546
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0091 0.0244
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0019 0.0009
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0043 0.0414 0.5783
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Echinococcus granulosus dna polymerase kappa 0.0016 0.0086 0.0227
Mycobacterium ulcerans sugar transporter 0.0027 0.0217 0.5239
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0091 0.0244
Leishmania major glucose transporter, lmgt3 0.006 0.0621 0.868
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0166 0.0489
Plasmodium falciparum importin beta, putative 0.0024 0.0185 0.017
Plasmodium falciparum mitogen-activated protein kinase 2 0.031 0.3734 0.3724
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0067 0.0715 1
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Echinococcus multilocularis short transient receptor potential channel 6 0.0054 0.0558 0.1744
Trichomonas vaginalis DNA polymerase eta, putative 0.0016 0.0086 0.038
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0039 0.0366 0.1135
Schistosoma mansoni ran 0.0018 0.0105 0.0288
Trichomonas vaginalis glucose transporter, putative 0.006 0.0621 0.274
Echinococcus multilocularis musashi 0.0023 0.0166 0.0482
Echinococcus multilocularis General substrate transporter 0.0165 0.193 0.6161
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Plasmodium falciparum ataxin-2 like protein, putative 0.0042 0.0403 0.0388
Mycobacterium ulcerans prolyl-tRNA synthetase 0.002 0.0134 0.3243
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0091 0.0244
Leishmania major hypothetical protein, conserved 0.0042 0.0403 0.5637
Trypanosoma brucei glucose transporter 2A 0.006 0.0621 0.868
Loa Loa (eye worm) hypothetical protein 0.0083 0.0916 0.2904
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0058 0.0597 0.187
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0091 0.0244
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0016 0.0086 0.038
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0058 0.0597 0.2634
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0091 0.0244
Loa Loa (eye worm) major facilitator superfamily transporter 0.0027 0.0217 0.0654
Echinococcus granulosus lamin 0.0023 0.0166 0.0482
Onchocerca volvulus 0.0027 0.0217 0.4472
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0091 0.0251
Trichomonas vaginalis glucose transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni importin beta-1 0.0024 0.0185 0.0546
Onchocerca volvulus 0.0027 0.0217 0.4472
Plasmodium vivax hexose transporter 0.0192 0.2266 0.2253
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0039 0.0366 0.1128
Plasmodium vivax CDK-related protein kinase 6, putative 0.0815 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Brugia malayi nuclear receptor NHR-88 0.0017 0.0091 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0091 0.0251
Brugia malayi hypothetical protein 0.0194 0.2285 1
Brugia malayi hypothetical protein 0.0027 0.0218 0.0893
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0011 0.0016 0.0262
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni terminal deoxycytidyl transferase 0.0016 0.0086 0.0227
Schistosoma mansoni glucose transport protein 0.0192 0.2266 0.7239
Toxoplasma gondii sugar transporter ST1 0.0027 0.0217 0.0327
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0039 0.0366 0.1545
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni intermediate filament proteins 0.0023 0.0166 0.0482
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0091 0.0334
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0043 0.0414 0.5783
Entamoeba histolytica deoxycytidyl transferase, putative 0.0016 0.0086 0.1182
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0091 0.0244
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0027 0.0217 0.6499
Schistosoma mansoni lysyl-tRNA synthetase 0.0043 0.0414 0.1281
Schistosoma mansoni lamin 0.0023 0.0166 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0091 0.0244
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0091 0.0244
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0091 0.0334
Schistosoma mansoni lamin 0.0023 0.0166 0.0482
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0036 0.0333 0.5587
Toxoplasma gondii LsmAD domain-containing protein 0.0042 0.0403 0.0609
Onchocerca volvulus 0.0039 0.0372 1
Leishmania major myo-inositol/proton symporter (MIT) 0.0027 0.0217 0.303
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0059 0.0611 0.1923
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0059 0.0611 0.1923
Onchocerca volvulus 0.0027 0.0217 0.4472
Onchocerca volvulus 0.0027 0.0217 0.4472
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0016 0.0086 0.258
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0039 0.0366 0.1128
Trichomonas vaginalis sugar transporter, putative 0.006 0.0621 0.274
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0091 0.0244
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0091 0.0244
Loa Loa (eye worm) hypothetical protein 0.0052 0.0524 0.164
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Echinococcus granulosus Sugar transporter ERD6 protein 0.0027 0.0217 0.0647
Onchocerca volvulus Putative transporter 0.0027 0.0217 0.4472
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0019 0.0115 0.0321
Brugia malayi Transient-receptor-potential like protein 0.0031 0.0262 0.1084
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0043 0.0414 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0042 0.0403 0.0388
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0067 0.0715 0.1081
Echinococcus multilocularis importin subunit beta 1 0.0024 0.0185 0.0546
Toxoplasma gondii transporter, major facilitator family protein 0.0027 0.0217 0.0327
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0016 0.0086 0.0227
Trichomonas vaginalis sugar transporter, putative 0.006 0.0621 0.274
Echinococcus granulosus solute carrier family 22 0.0027 0.0217 0.0647
Schistosoma mansoni transient receptor potential channel 0.0082 0.0904 0.2858
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0261 0.3124 1
Trichomonas vaginalis conserved hypothetical protein 0.0192 0.2266 1
Echinococcus multilocularis solute carrier family 22 0.0027 0.0217 0.0647
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0091 0.0251
Brugia malayi Latrophilin receptor protein 2 0.0026 0.0209 0.0852
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0091 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0091 0.0251
Echinococcus granulosus survival motor neuron protein 1 0.0194 0.2285 0.7301
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0166 0.0661
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0091 0.0244
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0038 0.0348 0.1536
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0086 0.1203
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0091 0.0334
Echinococcus granulosus General substrate transporter 0.0165 0.193 0.6161
Onchocerca volvulus 0.0023 0.0166 0.2647
Echinococcus multilocularis lysyl tRNA synthetase 0.0043 0.0414 0.1281
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0018 0.0105 0.1468
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0059 0.0611 0.1917
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0011 0.0016 0.0377
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0018 0.0105 0.0295
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0091 0.0244
Loa Loa (eye worm) major facilitator superfamily transporter 0.0027 0.0217 0.0654
Echinococcus granulosus GTP binding nuclear protein Ran 0.0018 0.0105 0.0288
Loa Loa (eye worm) hypothetical protein 0.0194 0.2285 0.7303
Trichomonas vaginalis glucose transporter, putative 0.006 0.0621 0.274
Schistosoma mansoni hypothetical protein 0.0026 0.0209 0.0622
Plasmodium falciparum lysine--tRNA ligase 0.0043 0.0414 0.0399
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0091 0.0334
Echinococcus granulosus synaptic vesicle 2 protein 0.0027 0.0217 0.0647
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0058 0.0597 0.9752
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0039 0.0366 0.1128
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0091 0.0244
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0027 0.0217 0.0647
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trypanosoma cruzi sugar transporter, putative 0.0027 0.0217 0.303
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0058 0.0597 0.2561
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0059 0.0612 0.0597
Schistosoma mansoni ran 0.0018 0.0105 0.0288
Echinococcus granulosus GPCR family 2 0.0026 0.0209 0.0622
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0019 0.0115 0.0321
Echinococcus granulosus solute carrier family 22 0.0027 0.0217 0.0647
Onchocerca volvulus 0.0027 0.0217 0.4472
Loa Loa (eye worm) hypothetical protein 0.0024 0.0185 0.0552
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0039 0.0366 0.1128
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0016 0.0086 0.0227
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0091 0.0334
Loa Loa (eye worm) hypothetical protein 0.0022 0.016 0.0473
Entamoeba histolytica protein kinase, putative 0.0059 0.0611 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0018 0.0105 0.0288
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0023 0.0315
Plasmodium falciparum calcium-dependent protein kinase 4 0.0059 0.0612 0.0597
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0023 0.0315
Leishmania major glucose transporter, lmgt2 0.006 0.0621 0.868
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Trypanosoma cruzi importin beta-1 subunit, putative 0.002 0.0128 0.1786
Schistosoma mansoni glucose transporter 0.0027 0.0217 0.0647
Trichomonas vaginalis myo-inositol transporter, putative 0.0027 0.0217 0.0956
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Onchocerca volvulus 0.0027 0.0217 0.4472
Echinococcus multilocularis synaptic vesicle 2 protein 0.0027 0.0217 0.0647
Giardia lamblia Prolyl-tRNA synthetase 0.0058 0.0597 1
Onchocerca volvulus 0.0027 0.0217 0.4472
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0018 0.0105 0.0159
Schistosoma mansoni thyroid hormone receptor 0.0017 0.0091 0.0244
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0016 0.0086 0.1203
Trichomonas vaginalis sugar transport protein, putative 0.0027 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0621 0.274
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0217 0.0956
Echinococcus granulosus short transient receptor potential channel 6 0.0054 0.0558 0.1744
Toxoplasma gondii lysine-tRNA ligase 0.0043 0.0414 0.0625
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Echinococcus multilocularis transient receptor potential gamma protein 0.0082 0.0904 0.2858
Toxoplasma gondii sugar transporter ST3 0.0027 0.0217 0.0327
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Plasmodium vivax proline--tRNA ligase, putative 0.0067 0.0715 0.0701
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0036 0.0333 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0019 0.0017
Brugia malayi hypothetical protein 0.0027 0.0217 0.0886
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0027 0.0217 0.0647
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0091 0.0334
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Brugia malayi latrophilin 2 splice variant baaae 0.0057 0.0589 0.2527
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0217 0.0956
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0091 0.0251
Schistosoma mansoni hypothetical protein 0.0026 0.0209 0.0622
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Loa Loa (eye worm) hypothetical protein 0.0058 0.0597 0.1876
Echinococcus granulosus short transient receptor potential channel 6 0.0054 0.0558 0.1744
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Schistosoma mansoni transient receptor potential channel 0.0054 0.0558 0.1744
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0059 0.0611 0.2626
Loa Loa (eye worm) hypothetical protein 0.0047 0.0463 0.1444
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0091 0.0244
Entamoeba histolytica protein kinase, putative 0.0059 0.0611 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0018 0.0105 0.1468
Trypanosoma cruzi hexose transporter, putative 0.0027 0.0217 0.303
Schistosoma mansoni protein kinase 0.0059 0.0611 0.1917
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0414 0.1826
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0043 0.0414 1
Onchocerca volvulus 0.0027 0.0217 0.4472
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0091 0.0251
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0091 0.0244
Trypanosoma cruzi hexose transporter, putative 0.0033 0.0286 0.3994
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0059 0.0612 0.0597
Mycobacterium ulcerans integral membrane transport protein 0.0027 0.0217 0.5239
Loa Loa (eye worm) hypothetical protein 0.0011 0.0016 0.0007
Schistosoma mansoni hypothetical protein 0.0026 0.0209 0.0622
Brugia malayi ecdysteroid receptor 0.0017 0.0091 0.0334
Echinococcus multilocularis transient receptor potential ion channel A 0.008 0.087 0.2748
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Leishmania major GTP-binding protein, putative 0.0018 0.0105 0.1468
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0011 0.0016 0.0218
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0091 0.0244
Trypanosoma brucei unspecified product 0.0016 0.0086 0.1203
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0091 0.0334
Schistosoma mansoni glucose transport protein 0.0192 0.2266 0.7239
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0034 0.0079
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0027 0.0217 0.6499
Entamoeba histolytica hypothetical protein 0.0043 0.0414 0.6679
Schistosoma mansoni hypothetical protein 0.0039 0.0372 0.1146
Loa Loa (eye worm) sugar transporter 0.0192 0.2266 0.7241
Trypanosoma brucei THT1 - hexose transporter, putative 0.006 0.0621 0.868
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0217 0.0956
Schistosoma mansoni hypothetical protein 0.0192 0.2266 0.7239
Brugia malayi lysyl-tRNA synthetase 0.0043 0.0414 0.1754
Onchocerca volvulus 0.0027 0.0217 0.4472
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0018 0.0105 0.009
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0043 0.0414 0.6932
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0091 0.0244
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0058 0.0597 0.187
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0091 0.0244
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0039 0.0372 0.1569
Echinococcus multilocularis dna polymerase kappa 0.0016 0.0086 0.0227
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0086 0.031
Trypanosoma brucei unspecified product 0.0011 0.0023 0.0315
Trypanosoma cruzi glucose transporter, putative 0.0027 0.0217 0.303
Plasmodium vivax importin-beta 2, putative 0.0024 0.0185 0.017
Toxoplasma gondii protein kinase, putative 0.0542 0.6617 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0091 0.0251
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0011 0.0016 0.0069
Echinococcus granulosus transient receptor potential gamma protein 0.0082 0.0904 0.2858
Echinococcus granulosus TRP transient receptor potential channel 0.0031 0.0262 0.0792
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0091 0.0244
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0026 0.0209 0.0852
Leishmania major DNA polymerase eta, putative 0.0016 0.0086 0.1203
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0086 0.1203
Onchocerca volvulus 0.0027 0.0217 0.4472
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Plasmodium vivax lysine--tRNA ligase, putative 0.0043 0.0414 0.0399
Loa Loa (eye worm) latrophilin receptor protein 2 0.0026 0.0209 0.0629
Loa Loa (eye worm) hypothetical protein 0.0082 0.0904 0.2863
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0059 0.0611 0.855
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0018 0.0105 0.0394
Loa Loa (eye worm) hypothetical protein 0.0059 0.0611 0.1923
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Onchocerca volvulus 0.0027 0.0217 0.4472
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0011 0.0016 0.0218
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0083 0.0916 0.2904
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Echinococcus granulosus calcium dependent protein kinase 0.0055 0.0566 0.1772
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0011 0.0016 0.0468
Brugia malayi Major Facilitator Superfamily protein 0.0027 0.0217 0.0886
Schistosoma mansoni hypothetical protein 0.0057 0.0589 0.1845
Trichomonas vaginalis Importin beta-1 subunit, putative 0.002 0.0128 0.0564
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0026 0.0209 0.0622
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Leishmania major DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Entamoeba histolytica Ran family GTPase 0.0018 0.0105 0.15
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Echinococcus multilocularis survival motor neuron protein 1 0.0194 0.2285 0.7301
Trichomonas vaginalis importin beta-1, putative 0.002 0.0128 0.0564
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0018 0.0105 0.1538
Trypanosoma brucei THT1 - hexose transporter, putative 0.006 0.0621 0.868
Trypanosoma brucei DNA polymerase IV, putative 0.0016 0.0086 0.1203
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trypanosoma brucei sugar transporter, putative 0.0027 0.0217 0.303
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0016 0.0086 0.0227
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0011 0.0016 0.0377
Plasmodium vivax sugar transporter, putative 0.0027 0.0217 0.0201
Schistosoma mansoni hypothetical protein 0.0019 0.0115 0.0321
Trypanosoma brucei THT1 - hexose transporter, putative 0.006 0.0621 0.868
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0091 0.0334
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0059 0.0612 0.0925
Trypanosoma cruzi hexose transporter, putative 0.006 0.0621 0.868
Schistosoma mansoni sugar transporter 0.0027 0.0217 0.0647
Brugia malayi major facilitator superfamily protein 0.0027 0.0217 0.0886
Trypanosoma cruzi PAB1-binding protein , putative 0.0042 0.0403 0.5637
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.0023 0.0315
Giardia lamblia Sugar-proton symporter 0.0027 0.0217 0.346
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.031 0.3734 0.3724
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0091 0.0334
Loa Loa (eye worm) hypothetical protein 0.0023 0.0166 0.0489
Onchocerca volvulus 0.0027 0.0217 0.4472
Loa Loa (eye worm) hypothetical protein 0.0043 0.0414 0.1287
Echinococcus multilocularis lamin dm0 0.0023 0.0166 0.0482
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0024 0.0175 0.052
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0091 0.0334
Echinococcus multilocularis short transient receptor potential channel 6 0.0054 0.0558 0.1744
Plasmodium falciparum hexose transporter 0.0192 0.2266 0.2253
Onchocerca volvulus 0.0027 0.0217 0.4472
Plasmodium falciparum calcium-dependent protein kinase 5 0.0059 0.0612 0.0597
Toxoplasma gondii facilitative glucose transporter GT1 0.0192 0.2266 0.3424
Brugia malayi Sugar transporter family protein 0.0027 0.0217 0.0886
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0091 0.0244
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0059 0.0612 0.0925
Echinococcus multilocularis thyroid hormone receptor alpha 0.0017 0.0091 0.0244
Brugia malayi Cam kinase protein 1 0.0059 0.0611 0.2626
Trichomonas vaginalis CAMK family protein kinase 0.0059 0.0611 0.2699
Loa Loa (eye worm) hypothetical protein 0.0016 0.0086 0.0234
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Toxoplasma gondii glycyl-tRNA synthetase 0.0011 0.0016 0.0024
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0091 0.0244
Schistosoma mansoni coup transcription factor 0.0017 0.0091 0.0244
Loa Loa (eye worm) hypothetical protein 0.0058 0.0597 0.1876
Plasmodium falciparum calcium-dependent protein kinase 3 0.0059 0.0612 0.0597
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Brugia malayi Major Facilitator Superfamily protein 0.0027 0.0217 0.0886
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0018 0.0105 0.009
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0091 0.0334
Leishmania major importin beta-1 subunit, putative 0.002 0.0128 0.1786
Echinococcus granulosus lamin dm0 0.0023 0.0166 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0611 0.1917
Giardia lamblia Hexose transporter 0.0027 0.0217 0.346
Trypanosoma brucei importin beta-1 subunit, putative 0.0024 0.0185 0.2589
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0027 0.0217 0.303
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0067 0.0715 1
Schistosoma mansoni sugar transporter 0.0027 0.0217 0.0647
Echinococcus multilocularis solute carrier family 22 0.0027 0.0217 0.0647
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0166 0.0489
Brugia malayi Calcitonin receptor-like protein seb-1 0.0083 0.0916 0.397
Loa Loa (eye worm) hypothetical protein 0.0028 0.0228 0.0689
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Onchocerca volvulus 0.0027 0.0217 0.4472
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0026 0.0209 0.0622
Trichomonas vaginalis sugar transporter, putative 0.006 0.0621 0.274
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Brugia malayi RNA, U transporter 1 0.007 0.0745 0.3215
Echinococcus granulosus snurportin 1 0.0261 0.3124 1
Plasmodium falciparum protein kinase 7 0.0542 0.6617 0.6612
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0067 0.0715 1
Schistosoma mansoni protein kinase 0.0059 0.0611 0.1917
Mycobacterium tuberculosis Conserved hypothetical protein 0.0016 0.0086 0.258
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Schistosoma mansoni sugar transporter 0.0027 0.0217 0.0647
Trypanosoma cruzi DNA polymerase eta, putative 0.0016 0.0086 0.1203
Schistosoma mansoni transient receptor potential channel 0.0054 0.0558 0.1744
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0019 0.0009
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0091 0.0244
Giardia lamblia DINP protein human, muc B family 0.0016 0.0086 0.1212
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0016 0.0086 0.0234
Echinococcus multilocularis calcium dependent protein kinase 0.0055 0.0566 0.1772
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0031 0.0262 0.0792
Loa Loa (eye worm) sugar transporter 0.0027 0.0217 0.0654
Trypanosoma cruzi hexose transporter 0.006 0.0621 0.868
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0091 0.0334
Leishmania major lysyl-tRNA synthetase, putative 0.0043 0.0414 0.5783
Leishmania major glucose transporter, lmgt1 0.006 0.0621 0.868
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0091 0.0334
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Leishmania major threonyl-tRNA synthetase, putative 0.0011 0.0016 0.0218
Trypanosoma cruzi hexose transporter, putative 0.006 0.0621 0.868
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0034 0.0065
Giardia lamblia Lysyl-tRNA synthetase 0.0043 0.0414 0.6849
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Mycobacterium ulcerans DNA polymerase IV 0.0016 0.0086 0.208
Echinococcus granulosus intermediate filament protein 0.0023 0.0166 0.0482
Onchocerca volvulus 0.0023 0.0166 0.2647
Schistosoma mansoni hypothetical protein 0.0261 0.3124 1
Echinococcus granulosus transient receptor potential ion channel A 0.008 0.087 0.2748
Brugia malayi ImpB/MucB/SamB family protein 0.0016 0.0086 0.031
Brugia malayi Sugar transporter family protein 0.0027 0.0217 0.0886
Leishmania major hypothetical protein, conserved 0.0027 0.0217 0.303
Schistosoma mansoni hypothetical protein 0.0026 0.0209 0.0622
Echinococcus granulosus lysyl tRNA synthetase 0.0043 0.0414 0.1281
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0067 0.0715 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0058 0.0597 0.2561
Brugia malayi Major Facilitator Superfamily protein 0.0027 0.0217 0.0886
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0091 0.0244
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0039 0.0366 0.1128
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0027 0.0217 0.5239
Echinococcus multilocularis lamin 0.0023 0.0166 0.0482
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0091 0.0244
Chlamydia trachomatis lysine--tRNA ligase 0.0043 0.0414 1
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0026 0.0209 0.0622
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0192 0.2266 0.7239
Trypanosoma brucei importin beta-1 subunit, putative 0.0024 0.0185 0.2589
Plasmodium falciparum calcium-dependent protein kinase 1 0.0059 0.0612 0.0597
Plasmodium falciparum calcium-dependent protein kinase 2 0.0059 0.0612 0.0597
Trichomonas vaginalis ran, putative 0.0018 0.0105 0.0463
Leishmania major protein kinase, putative 0.0059 0.0611 0.855
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0621 0.274
Brugia malayi Sugar transporter family protein 0.0192 0.2266 0.9915
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0059 0.0612 0.0597
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0091 0.0251
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0091 0.0244
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0027 0.0217 0.0201
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0058 0.0597 0.187
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0011 0.0016 0.0007
Echinococcus granulosus solute carrier family 22 0.0027 0.0217 0.0647
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0091 0.0334
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0058 0.0597 1
Echinococcus multilocularis GPCR, family 2 0.0026 0.0209 0.0622
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0083 0.0916 0.397
Schistosoma mansoni transient receptor potential channel 4 0.0082 0.0904 0.2858
Loa Loa (eye worm) hypothetical protein 0.0031 0.0262 0.0798
Loa Loa (eye worm) hypothetical protein 0.0026 0.0209 0.0629
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0058 0.0597 0.187
Leishmania major glucose transporter/membrane transporter D2, putative 0.006 0.0621 0.868
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trypanosoma cruzi PAB1-binding protein , putative 0.0042 0.0403 0.5637
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0026 0.0209 0.0622
Plasmodium vivax ataxin-2 like protein, putative 0.0042 0.0403 0.0388
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Brugia malayi intermediate filament protein 0.0023 0.0166 0.0661
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0192 0.2266 0.7239
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0067 0.0715 1
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0027 0.0217 0.5239
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Brugia malayi steroid hormone receptor 0.0017 0.0091 0.0334
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0039 0.0366 0.1128
Echinococcus multilocularis dna polymerase eta 0.0016 0.0086 0.0227
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trypanosoma brucei DNA polymerase eta, putative 0.0016 0.0086 0.1203
Schistosoma mansoni survival motor neuron protein 0.0039 0.0372 0.1146
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0011 0.0016 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Plasmodium falciparum proline--tRNA ligase 0.0067 0.0715 0.0701
Entamoeba histolytica hypothetical protein 0.002 0.0128 0.1882
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0091 0.0244
Brugia malayi major facilitator superfamily protein 0.0027 0.0217 0.0886
Toxoplasma gondii sugar transporter ST2 0.0027 0.0217 0.0327
Onchocerca volvulus 0.0027 0.0217 0.4472
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0091 0.0244
Mycobacterium ulcerans DNA polymerase IV 0.0016 0.0086 0.208
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0039 0.0366 0.1128
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0011 0.0016 0.0218
Echinococcus granulosus solute carrier family 22 0.0027 0.0217 0.0647
Loa Loa (eye worm) hypothetical protein 0.0017 0.0091 0.0251
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0059 0.0611 0.1917
Schistosoma mansoni DNA polymerase eta 0.0016 0.0086 0.0227
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni glucose transport protein 0.0192 0.2266 0.7239
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Trypanosoma cruzi hexose transporter, putative 0.006 0.0621 0.868
Brugia malayi hypothetical protein 0.0042 0.0403 0.1708
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0027 0.0217 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0091 0.0244
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni lysyl-tRNA synthetase 0.0043 0.0414 0.1281
Echinococcus multilocularis solute carrier family 22 0.0027 0.0217 0.0647
Trypanosoma brucei glucose transporter, putative 0.006 0.0621 0.868
Loa Loa (eye worm) hypothetical protein 0.0042 0.0403 0.1253
Loa Loa (eye worm) hypothetical protein 0.0027 0.0217 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0217 0.0956
Trypanosoma cruzi DNA polymerase kappa, putative 0.0016 0.0086 0.1203
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Trypanosoma brucei unspecified product 0.0011 0.0023 0.0315
Trichomonas vaginalis sugar transporter, putative 0.0027 0.0217 0.0956
Schistosoma mansoni protein kinase 0.0059 0.0611 0.1917

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 32 % Antinociceptive activity in OF1 mouse acute central pain model at 150 mg/kg, po administered with EtOH/PEG400/water after 20 mins by hot plate test relative to vehicle-treated control ChEMBL. 24927250

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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