Detailed information for compound 2069265

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.305 | Formula: C16H15F2N3O3
  • H donors: 0 H acceptors: 4 LogP: 2.21 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C(N(C(=O)c1ccnc(n1)C)C)c1cc(F)ccc1F
  • InChi: 1S/C16H15F2N3O3/c1-9-19-7-6-13(20-9)15(22)21(2)14(16(23)24-3)11-8-10(17)4-5-12(11)18/h4-8,14H,1-3H3
  • InChiKey: SJWLYIRNFUJWSK-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0057 0.0115 0.0172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0021 0.003 0.5
Trichomonas vaginalis AGC family protein kinase 0.003 0.0051 0.0558
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0021 0.003 0.5
Giardia lamblia Kinase, CMGC CDK 0.0024 0.0037 0.8211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0058
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0316 0.0744 0.1736
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0037 0.0067 0.0157
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Loa Loa (eye worm) voltage-dependent calcium channel 0.0037 0.0067 0.0101
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.0067 0.0898
Trichomonas vaginalis glutathione reductase, putative 0.0021 0.003 0.0324
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0028 0.0045 0.013
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0021 0.003 0.0394
Leishmania major trypanothione reductase 0.0062 0.0128 0.0373
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0037 0.0067 0.0157
Giardia lamblia GTOR 0.0028 0.0045 1
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0037 0.0067 0.0081
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0021 0.003 0.0036
Schistosoma mansoni transient receptor potential channel 4 0.0037 0.0067 0.0081
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0028 0.0045 0.0088
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.0067 0.0157
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0016 0.017
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0067 0.0101
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0316 0.0744 0.1471
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0086
Toxoplasma gondii hypothetical protein 0.0037 0.0067 0.0898
Leishmania major hypothetical protein, unknown function 0.0037 0.0067 0.0196
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0028 0.0045 0.0104
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0021 0.003 0.0058
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0037 0.0067 0.0133
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0037 0.0067 0.0898
Echinococcus multilocularis cyclin dependent kinase 0.0024 0.0037 0.0086
Trichomonas vaginalis kcs1 protein, putative 0.0009 0.0001 0.0006
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.002 0.0025 0.0276
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0067 0.0157
Echinococcus multilocularis cyclin dependent kinase 1 0.0024 0.0037 0.0086
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0021 0.003 0.5
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0021 0.003 0.003
Trypanosoma cruzi CYC2-like cyclin 6, putative 0.0015 0.0013 0.0025
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.0067 0.0157
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.003 0.0051 0.0077
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0037 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0018 0.0194
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.0067 0.0081
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.003 0.0058
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0316 0.0744 1
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0047 0.0091 0.1216
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0067 0.0731
Echinococcus multilocularis hyperpolarization activated cyclic 0.0037 0.0067 0.0157
Schistosoma mansoni transient receptor potential channel 0.0037 0.0067 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0316 0.0744 0.1736
Brugia malayi Cytohesin 3 0.0173 0.0396 0.0396
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0058
Leishmania major inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0081 0.0173 0.0504
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0016 0.0016 0.0032
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.003 0.0051 0.0119
Loa Loa (eye worm) hypothetical protein 0.0177 0.0407 0.0611
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0067 0.0157
Brugia malayi Transient-receptor-potential like protein 0.0037 0.0067 0.0067
Brugia malayi glutathione reductase 0.0062 0.0128 0.0128
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Echinococcus multilocularis voltage dependent calcium channel 0.0037 0.0067 0.0157
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0037 0.0067 0.0067
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0021 0.003 0.0394
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0021 0.003 0.0069
Loa Loa (eye worm) AGC/AKT protein kinase 0.002 0.0026 0.0039
Toxoplasma gondii NADPH-glutathione reductase 0.0021 0.003 0.0394
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0067 0.0157
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.0067 0.0081
Echinococcus granulosus cytohesin 1 0.0173 0.0396 0.0925
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Brugia malayi fructose-bisphosphate aldolase 2 0.0316 0.0744 0.0743
Trypanosoma brucei rac serine-threonine kinase, putative 0.002 0.0026 0.0051
Echinococcus granulosus voltage gated potassium channel 0.0037 0.0067 0.0157
Trypanosoma brucei glycosylphosphatidylinositol-specific phospholipase C 0.002 0.0025 0.005
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0067 0.0157
Schistosoma mansoni transient receptor potential channel 0.0037 0.0067 0.0081
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0037 0.0067 0.0067
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0095 0.0209 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0035 0.0381
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0013 0.0009 0.0013
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0067 0.0157
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0037 0.0067 0.0196
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.0073 0.0154 0.0304
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0037 0.0067 0.0731
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Schistosoma mansoni phospholipase C beta 0.002 0.0025 0.003
Schistosoma mansoni phospholipase C beta 0.0109 0.0242 0.0291
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0316 0.0744 0.1736
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Echinococcus multilocularis transfer RNA-Gly 0.0037 0.0067 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0018 0.0194
Echinococcus multilocularis hyperpolarization activated cyclic 0.0037 0.0067 0.0157
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0037 0.0067 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0 0.0003
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Echinococcus multilocularis potassium large conductance calcium activated 0.0037 0.0067 0.0157
Brugia malayi MIR domain containing protein 0.0389 0.0921 0.092
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0037 0.0067 0.0157
Loa Loa (eye worm) voltage-gated potassium channel 0.0037 0.0067 0.0101
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0316 0.0744 1
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0024 0.0037 0.0107
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.0067 0.0898
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0022 0.0031 0.009
Echinococcus granulosus voltage gated hydrogen channel 1 0.0037 0.0067 0.0157
Echinococcus granulosus shaker cognate 0.0037 0.0067 0.0157
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0037 0.0067 0.0725
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0028 0.0045 0.0088
Trypanosoma cruzi inositol polyphosphate kinase-like protein, putative 0.0009 0.0001 0.0001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0021 0.003 0.0058
Plasmodium falciparum protein kinase 5 0.0024 0.0037 0.049
Brugia malayi hypothetical protein 0.0037 0.0067 0.0067
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0037 0.0044
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0037 0.0067 0.0067
Trichomonas vaginalis 1-phosphatidylinositol phosphodiesterase, putative 0.002 0.0025 0.0276
Echinococcus granulosus ryanodine receptor 44f 0.1777 0.4281 1
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0028 0.0045 0.013
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0058
Schistosoma mansoni voltage-dependent calcium channel 0.0037 0.0067 0.0081
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.0067 0.0157
Leishmania major hypothetical protein, conserved 0.002 0.0025 0.0073
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0109 0.0242 0.0241
Echinococcus multilocularis ryanodine receptor 44f 0.1777 0.4281 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0021 0.003 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0045 0.0488
Brugia malayi p70 ribosomal S6 kinase beta 0.0013 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Trypanosoma cruzi inositol polyphosphate kinase, putative 0.0009 0.0001 0.0001
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0016 0.0016 0.0016
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0028 0.0045 0.0054
Trypanosoma cruzi Protein kinase B 0.0016 0.0016 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0021 0.0232
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0058
Echinococcus granulosus serine/threonine protein kinase 0.0016 0.0016 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0031 0.0338
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0067 0.0157
Plasmodium falciparum thioredoxin reductase 0.0062 0.0128 0.1715
Entamoeba histolytica cell division protein kinase 2, putative 0.0024 0.0037 0.0396
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.0067 0.0157
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.003 0.0051 0.0077
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0021 0.003 0.5
Loa Loa (eye worm) glutathione reductase 0.0062 0.0128 0.0192
Plasmodium falciparum glutathione reductase 0.0062 0.0128 0.1715
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Entamoeba histolytica PH domain containing protein kinase, putative 0.0016 0.0016 0.017
Trypanosoma cruzi inositol polyphosphate kinase, putative 0.0009 0.0001 0.0001
Plasmodium falciparum cyclin, putative 0.0015 0.0013 0.0166
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0067 0.0081
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0316 0.0744 0.1471
Loa Loa (eye worm) hypothetical protein 0.2713 0.655 0.9834
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0037 0.0067 0.0157
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0131 0.0295 0.0295
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0037 0.0067 0.0067
Leishmania major fructose-1,6-bisphosphate aldolase 0.0316 0.0744 0.2168
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0316 0.0744 0.1116
Schistosoma mansoni transient receptor potential channel 0.0037 0.0067 0.0081
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0037 0.0067 0.0157
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0037 0.0067 0.0898
Trypanosoma brucei CYC2-like cyclin, putative 0.0015 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Loa Loa (eye worm) hypothetical protein 0.0047 0.0091 0.0136
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0067 0.0081
Trypanosoma brucei cdc2-related kinase 3 0.0024 0.0037 0.0073
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Loa Loa (eye worm) cytohesin 3 0.0173 0.0396 0.0594
Echinococcus multilocularis cytohesin 1 0.0173 0.0396 0.0925
Echinococcus granulosus voltage gated potassium channel 0.0037 0.0067 0.0157
Loa Loa (eye worm) hypothetical protein 0.0112 0.0248 0.0373
Trypanosoma cruzi CYC2-like cyclin 4, putative 0.0015 0.0013 0.0025
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Plasmodium falciparum glutathione reductase 0.0021 0.003 0.0394
Echinococcus multilocularis inositol trisphosphate 3 kinase C 0.0009 0.0001 0.0001
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0037 0.0067 0.0157
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0037 0.0067 0.0157
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0037 0.0067 0.0067
Echinococcus granulosus inositol trisphosphate 3 kinase C 0.0009 0.0001 0.0001
Schistosoma mansoni phospholipase C-like protein 2 plc-L2 0.0082 0.0176 0.0212
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.0067 0.0081
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Trypanosoma cruzi cdc2-related kinase 3 0.0024 0.0037 0.0073
Loa Loa (eye worm) hypothetical protein 0.2361 0.5696 0.8552
Brugia malayi phospholipase C homolog 0.003 0.005 0.005
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0067 0.0157
Trypanosoma brucei trypanothione reductase 0.0062 0.0128 0.0253
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0021 0.003 0.0086
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0021 0.003 0.0069
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0086
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0 0.0003
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Echinococcus multilocularis voltage dependent calcium channel 0.0037 0.0067 0.0157
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0128 0.0253
Echinococcus granulosus hyperpolarization activated cyclic 0.0037 0.0067 0.0157
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0021 0.003 0.5
Schistosoma mansoni stromal cell-derived factor 2 precursor-like protein 0.0389 0.0921 0.1111
Trypanosoma brucei inositol polyphosphate multikinase 0.0009 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.0023 0.0248
Trypanosoma cruzi cdc2-related kinase 1 0.0024 0.0037 0.0073
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0037 0.0401
Brugia malayi phosphoinositide-dependent protein kinase I 0.003 0.0051 0.0051
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0037 0.0067 0.0101
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0067 0.0157
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.003 0.0058
Trypanosoma cruzi CYC2-like cyclin, putative 0.0015 0.0013 0.0025
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0067 0.0157
Leishmania major CYC2-like cyclin, putative 0.0015 0.0013 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0017 0.019
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0067 0.0157
Trichomonas vaginalis inositol polyphosphate multikinase, putative 0.0009 0.0001 0.0006
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0016 0.0016 0.0016
Echinococcus granulosus two pore calcium channel protein 1 0.0037 0.0067 0.0157
Echinococcus multilocularis cyclin dependent kinase 1 0.0024 0.0037 0.0086
Entamoeba histolytica MIR domain protein 0.0389 0.0921 1
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0037 0.0067 0.0157
Brugia malayi Protein kinase domain containing protein 0.002 0.0026 0.0026
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0028 0.0045 0.0482
Echinococcus multilocularis voltage gated potassium channel 0.0037 0.0067 0.0157
Echinococcus multilocularis two pore calcium channel protein 2 0.0037 0.0067 0.0157
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0037 0.0067 0.0157
Echinococcus granulosus thioredoxin glutathione reductase 0.0062 0.0128 0.0298
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.0067 0.0157
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0084 0.0182 0.036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0017 0.019
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.0067 0.0081
Echinococcus multilocularis calcium activated potassium channel 0.0038 0.0069 0.016
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.0067 0.0157
Brugia malayi Protein kinase domain containing protein 0.003 0.0051 0.0051
Plasmodium vivax protein kinase Crk2 0.0024 0.0037 0.049
Trypanosoma brucei cyclin 2 0.0015 0.0013 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0 0.0003
Trypanosoma cruzi inositol polyphosphate kinase-like protein, putative 0.0009 0.0001 0.0001
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0037 0.0067 0.0081
Brugia malayi Cyclic-nucleotide gated cation channel 0.0037 0.0067 0.0067
Entamoeba histolytica protein kinase, putative 0.002 0.0026 0.0279
Schistosoma mansoni voltage-gated ion channel 0.0037 0.0067 0.0081
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0316 0.0744 0.1736
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0028 0.0045 0.0045
Brugia malayi Thioredoxin reductase 0.0062 0.0128 0.0128
Echinococcus multilocularis sodium channel protein 0.0037 0.0067 0.0157
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0021 0.003 0.5
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0067 0.0157
Toxoplasma gondii target of rapamycin (TOR), putative 0.0021 0.0028 0.0365
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.0067 0.0157
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0316 0.0744 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.0067 0.0157
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0037 0.0067 0.0067
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.0067 0.0157
Onchocerca volvulus 0.0037 0.0067 0.0725
Schistosoma mansoni two-pore calcium channel 0.0037 0.0067 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0013 0.014
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0067 0.0157
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0047 0.0091 0.0091
Echinococcus multilocularis inositol polyphosphate kinase 0.0009 0.0001 0.0001
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0037 0.0067 0.0157
Schistosoma mansoni vesicular amine transporter 0.0037 0.0067 0.0081
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.0112 0.0248 0.058
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0173 0.0396 0.0478
Loa Loa (eye worm) voltage-gated calcium channel 0.0037 0.0067 0.0101
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0037 0.0067 0.0157
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0024 0.0037 0.049
Treponema pallidum NADH oxidase 0.0021 0.003 0.5
Trypanosoma cruzi target of rapamycin kinase 3 0.0022 0.0031 0.0061
Leishmania major inositol polyphosphate kinase-like protein, putative 0.0009 0.0001 0.0001
Echinococcus granulosus hypothetical protein 0.0037 0.0067 0.0157
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.0067 0.0157
Trichomonas vaginalis AGC family protein kinase 0.003 0.0051 0.0558
Trypanosoma brucei inositol hexakisphosphate kinase 0.0009 0.0001 0.0001
Trichomonas vaginalis mercuric reductase, putative 0.0021 0.003 0.0324
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.0073 0.0154 0.0304
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.2484 0.5996 0.5996
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.0067 0.0157
Schistosoma mansoni serine/threonine-protein kinase 0.0016 0.0016 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0001 0.0006
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.0067 0.0157
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0021 0.003 0.0394
Echinococcus granulosus cyclin dependent kinase 1 0.0024 0.0037 0.0086
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0001 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Leishmania major hypothetical protein, conserved 0.1424 0.3428 1
Echinococcus granulosus inositol polyphosphate kinase 0.0009 0.0001 0.0001
Echinococcus multilocularis conserved hypothetical protein 0.0037 0.0067 0.0157
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0067 0.0157
Echinococcus granulosus sodium leak channel non selective protein 0.0037 0.0067 0.0157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0037 0.0067 0.0067
Loa Loa (eye worm) calcium channel 0.0037 0.0067 0.0101
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0067 0.0157
Leishmania major phosphoinositide-specific phospholipase C, putative 0.007 0.0147 0.0428
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0047 0.0091 0.0264
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.0067 0.0081
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0051 0.0062
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.0067 0.0157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Toxoplasma gondii transporter, cation channel family protein 0.0037 0.0067 0.0898
Loa Loa (eye worm) hypothetical protein 0.0081 0.0173 0.0259
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0037 0.0067 0.0101
Loa Loa (eye worm) hypothetical protein 0.0066 0.0137 0.0205
Loa Loa (eye worm) MIR domain-containing protein 0.0389 0.0921 0.1382
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0028 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.1777 0.4281 0.6428
Schistosoma mansoni hypothetical protein 0.0037 0.0067 0.0081
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0024 0.0037 0.0086
Loa Loa (eye worm) hypothetical protein 0.0081 0.0173 0.0259
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.0067 0.0157
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0037 0.0067 0.0067
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0062 0.0128 1
Echinococcus granulosus transient receptor potential gamma protein 0.0037 0.0067 0.0157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0058
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0316 0.0744 0.1116
Onchocerca volvulus 0.0066 0.0137 0.1481
Loa Loa (eye worm) voltage-gated potassium channel 0.0037 0.0067 0.0101
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0037 0.0067 0.0157
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0037 0.0401
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.003 0.0051 0.0119
Schistosoma mansoni serine/threonine-protein kinase 0.0016 0.0016 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0021 0.003 0.0058
Onchocerca volvulus 0.0193 0.0446 0.4843
Echinococcus multilocularis cyclin dependent kinase 5 0.0024 0.0037 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0316 0.0744 0.1736
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0037 0.0067 0.0157
Brugia malayi Protein kinase domain containing protein 0.0024 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0021 0.003 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0018 0.0194
Plasmodium vivax glutathione reductase, putative 0.0062 0.0128 0.1715
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Brugia malayi ion channel NompC 0.0037 0.0067 0.0067
Plasmodium vivax cyclin, putative 0.0015 0.0013 0.0166
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0067 0.0157
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0028 0.0045 0.0088
Schistosoma mansoni ryanodine receptor 1 skeletal muscle 0.0671 0.1603 0.1934
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0012 0.0006 0.0011
Echinococcus multilocularis inositol polyphosphate multikinase 0.0009 0.0001 0.0001
Echinococcus multilocularis shaker cognate 0.0037 0.0067 0.0157
Echinococcus granulosus sodium channel protein 0.0037 0.0067 0.0157
Trichomonas vaginalis kcs1 protein, putative 0.0009 0.0001 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0021 0.003 0.0058
Schistosoma mansoni voltage-gated cation channel 0.0037 0.0067 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Brugia malayi phospholipase C homolog 0.0082 0.0176 0.0176
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0316 0.0744 0.1471
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.0067 0.0157
Echinococcus granulosus stromal cell derived factor 2 0.0389 0.0921 0.215
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.002 0.0025 0.0038
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.0108 0.0239 0.3215
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Echinococcus granulosus voltage dependent calcium channel 0.0037 0.0067 0.0157
Onchocerca volvulus 0.0389 0.0921 1
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0037 0.0067 0.0067
Brugia malayi Variant SH3 domain containing protein 0.0057 0.0115 0.0115
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0022 0.0031 0.0061
Trypanosoma cruzi cdc2-related kinase 3 0.0024 0.0037 0.0073
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.0131 0.0295 0.0443
Trichomonas vaginalis AGC family protein kinase 0.0012 0.0007 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0 0.0003
Onchocerca volvulus 0.002 0.0025 0.027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0024 0.0037 0.0107
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0024 0.0037 0.0055
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0067 0.0157
Schistosoma mansoni ryanodine receptor related 0.2484 0.5996 0.7236
Entamoeba histolytica protein kinase, putative 0.002 0.0026 0.0279
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Schistosoma mansoni inositol 145-trisphosphate receptor 0.2361 0.5696 0.6875
Echinococcus granulosus potassium voltage gated channel protein 0.0037 0.0067 0.0157
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0021 0.003 0.0394
Onchocerca volvulus 0.0135 0.0304 0.3302
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0045 0.0488
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0037 0.0067 0.0157
Echinococcus granulosus cyclin dependent kinase 5 0.0024 0.0037 0.0086
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0021 0.003 0.0086
Plasmodium falciparum thioredoxin reductase 0.0021 0.003 0.0394
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0316 0.0744 0.1471
Toxoplasma gondii AGC kinase 0.0013 0.0009 0.0111
Brugia malayi voltage-dependent calcium channel 0.0037 0.0067 0.0067
Toxoplasma gondii cyclin2 related protein 0.0015 0.0013 0.0166
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0015 0.0013 0.0166
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0316 0.0744 0.1736
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0045 0.0488
Brugia malayi fructose-bisphosphate aldolase 1 0.0316 0.0744 0.0743
Plasmodium vivax thioredoxin reductase, putative 0.0062 0.0128 0.1715
Loa Loa (eye worm) thioredoxin reductase 0.0062 0.0128 0.0192
Echinococcus granulosus voltage dependent calcium channel 0.0037 0.0067 0.0157
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0067 0.0081
Trichomonas vaginalis inositol polyphosphate kinase, putative 0.0009 0.0001 0.0006
Loa Loa (eye worm) Plcb4 protein 0.0109 0.0242 0.0362
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0021 0.003 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0031 0.0338
Giardia lamblia Kinase, CMGC CDK 0.0024 0.0037 0.8211
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.0067 0.0157
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0037 0.0067 0.0067
Echinococcus granulosus inositol polyphosphate multikinase 0.0009 0.0001 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trichomonas vaginalis transcription factor, putative 0.0009 0.0001 0.0006
Trypanosoma cruzi cdc2-related kinase 1 0.0024 0.0037 0.0073
Loa Loa (eye worm) phosphatidylinositol 3 0.0028 0.0045 0.0067
Echinococcus granulosus potassium large conductance calcium activated 0.0037 0.0067 0.0157
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.0067 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0031 0.0338
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0024 0.0037 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0031 0.0338
Leishmania major hypothetical protein, conserved 0.0009 0.0001 0.0001
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Echinococcus granulosus ryanodine receptor 44f 0.1379 0.3317 0.7748
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0316 0.0744 0.0897
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.0067 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trichomonas vaginalis mannosyltransferase 1, putative 0.0389 0.0921 1
Schistosoma mansoni calcium-activated potassium channel 0.0037 0.0067 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Entamoeba histolytica protein kinase, putative 0.003 0.0051 0.0552
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0037 0.0067 0.0067
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0028 0.0045 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0037 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0037 0.0067 0.0081
Plasmodium vivax phospholipase C-like, putative 0.0047 0.0091 0.1216
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0081 0.0173 0.0342
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Brugia malayi cell division control protein 2 homolog 0.0024 0.0037 0.0037
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0316 0.0744 0.1471
Loa Loa (eye worm) hypothetical protein 0.2759 0.6661 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0037 0.0067 0.0157
Schistosoma mansoni 60S ribosomal protein L21 0.0037 0.0067 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0067 0.0067
Entamoeba histolytica cell division protein kinase 2, putative 0.0024 0.0037 0.0396
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0037 0.0067 0.0157
Brugia malayi cation channel family protein 0.0037 0.0067 0.0067
Echinococcus multilocularis ryanodine receptor 44f 0.1379 0.3317 0.7748
Echinococcus multilocularis two pore calcium channel protein 1 0.0037 0.0067 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0028 0.0301
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0037 0.0067 0.0157
Leishmania major phospholipase c-like protein 0.0073 0.0154 0.0447
Echinococcus multilocularis thioredoxin glutathione reductase 0.0062 0.0128 0.0298
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.2095 0.5053 1
Loa Loa (eye worm) ryanodine receptor 0.0671 0.1603 0.2406
Toxoplasma gondii thioredoxin reductase 0.0062 0.0128 0.1715
Trichomonas vaginalis AGC family protein kinase 0.002 0.0026 0.0284
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0028 0.0045 0.0088
Echinococcus granulosus calcium activated potassium channel 0.0038 0.0069 0.016
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0316 0.0744 1
Echinococcus granulosus hyperpolarization activated cyclic 0.0037 0.0067 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0031 0.0338
Loa Loa (eye worm) ion channel NompC 0.0037 0.0067 0.0101
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0037 0.0067 0.0157
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0316 0.0744 0.1736
Echinococcus multilocularis transient receptor potential gamma protein 0.0037 0.0067 0.0157
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.0067 0.0157
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0037 0.0067 0.0081
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0013 0.001 0.0018
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0037 0.0067 0.0081
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0037 0.0067 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0037 0.0067 0.0101
Echinococcus granulosus cyclin dependent kinase 0.0024 0.0037 0.0086
Echinococcus multilocularis rac serine:threonine kinase 0.0016 0.0016 0.0037
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0037 0.0067 0.0157
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0037 0.0067 0.0725
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.0112 0.0248 0.058
Echinococcus multilocularis sodium leak channel non selective protein 0.0037 0.0067 0.0157
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0037 0.0067 0.0157
Toxoplasma gondii hypothetical protein 0.0037 0.0067 0.0898
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0037 0.0067 0.0157
Loa Loa (eye worm) hypothetical protein 0.0081 0.0173 0.0259
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0316 0.0744 0.0897
Entamoeba histolytica protein kinase, putative 0.0013 0.0009 0.0089
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0037 0.0067 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0037 0.0067 0.0133
Brugia malayi olfactory channel protein osm-9 0.0037 0.0067 0.0067
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.002 0.0025 0.0025
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0037 0.0067 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0 0.0003
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0316 0.0744 0.1736
Trichomonas vaginalis AGC family protein kinase 0.003 0.0051 0.0558
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.2095 0.5053 1
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0037 0.0067 0.0067
Plasmodium falciparum fructose-bisphosphate aldolase 0.0316 0.0744 1
Trichomonas vaginalis CMGC family protein kinase 0.0024 0.0037 0.0401
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Trypanosoma cruzi inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0081 0.0173 0.0342
Echinococcus granulosus two pore calcium channel protein 2 0.0037 0.0067 0.0157
Giardia lamblia NADH oxidase lateral transfer candidate 0.0021 0.003 0.6602
Trypanosoma cruzi trypanothione reductase, putative 0.0021 0.003 0.0058
Schistosoma mansoni inositol 145-trisphosphate receptor 0.343 0.8286 1
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Trypanosoma brucei cdc2-related kinase 1 0.0024 0.0037 0.0073
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0037 0.0067 0.0157
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0024 0.0037 0.0055
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0037 0.0067 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0014 0.0152
Echinococcus multilocularis stromal cell derived factor 2 0.0389 0.0921 0.215
Schistosoma mansoni voltage-gated potassium channel 0.0037 0.0067 0.0081
Loa Loa (eye worm) ryanodine receptor 0.0037 0.0067 0.0101
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0037 0.0067 0.0157

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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