Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.044 | 0.5695 | 0.8223 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.0277 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0264 | 0.3357 | 0.3357 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0356 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0371 | 0.4784 | 0.4741 |
Schistosoma mansoni | sulfide quinone reductase | 0.007 | 0.077 | 0.0697 |
Trypanosoma brucei | aminopeptidase, putative | 0.0054 | 0.0561 | 0.0561 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.007 | 0.077 | 0.0429 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.007 | 0.077 | 0.1378 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.007 | 0.077 | 0.0635 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0791 | 0.0717 |
Schistosoma mansoni | hypothetical protein | 0.0325 | 0.4164 | 0.4118 |
Schistosoma mansoni | thyroid hormone receptor | 0.0148 | 0.1804 | 0.1739 |
Echinococcus multilocularis | aminopeptidase N | 0.0526 | 0.6849 | 0.6803 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0054 | 0.0561 | 0.0561 |
Mycobacterium ulcerans | hydrolase | 0.0241 | 0.3053 | 0.8985 |
Echinococcus granulosus | protein cereblon | 0.0325 | 0.4164 | 0.4079 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.007 | 0.077 | 0.0671 |
Echinococcus multilocularis | protein cereblon | 0.0325 | 0.4164 | 0.4079 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Schistosoma mansoni | disulfide oxidoreductase | 0.007 | 0.077 | 0.0697 |
Onchocerca volvulus | 0.046 | 0.5972 | 0.8649 | |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0241 | 0.3053 | 0.2951 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.0356 | 0.0277 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Brugia malayi | hypothetical protein | 0.0325 | 0.4164 | 0.4079 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.007 | 0.077 | 0.1849 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0054 | 0.0561 | 0.0561 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.007 | 0.077 | 0.0635 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0356 | 0.0215 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0148 | 0.1804 | 0.1684 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.007 | 0.077 | 0.0635 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.007 | 0.077 | 0.077 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.0356 | 0.0314 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.077 | 0.077 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0054 | 0.0561 | 0.167 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.007 | 0.077 | 0.0429 |
Schistosoma mansoni | sulfide quinone reductase | 0.007 | 0.077 | 0.0697 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0264 | 0.3357 | 1 |
Brugia malayi | glutamate synthase | 0.007 | 0.077 | 0.0635 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0264 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.0277 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.0356 | 0.0215 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0054 | 0.0561 | 0.0423 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0762 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.046 | 0.5972 | 0.5939 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0155 | 0.19 | 0.1835 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0264 | 0.3357 | 0.3357 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0356 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.077 | 0.0694 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0791 | 0.0656 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.007 | 0.077 | 0.2293 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.007 | 0.077 | 0.0729 |
Brugia malayi | Animal haem peroxidase family protein | 0.046 | 0.5972 | 0.5913 |
Toxoplasma gondii | aminopeptidase N protein | 0.0054 | 0.0561 | 0.0522 |
Onchocerca volvulus | 0.0526 | 0.6849 | 1 | |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0054 | 0.0561 | 0.0561 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.007 | 0.077 | 0.0429 |
Brugia malayi | Matrixin family protein | 0.0198 | 0.2477 | 0.2367 |
Echinococcus granulosus | glutamate synthase | 0.007 | 0.077 | 0.0635 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0791 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0561 | 0.0483 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.007 | 0.077 | 0.1378 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.007 | 0.077 | 0.1849 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0762 | 1 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0264 | 0.3357 | 0.3286 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.007 | 0.077 | 0.077 |
Trichomonas vaginalis | glutamate synthase, putative | 0.007 | 0.077 | 0.2293 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.007 | 0.077 | 0.077 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.007 | 0.077 | 0.0729 |
Brugia malayi | TATA binding protein associated factor | 0.0054 | 0.0561 | 0.0423 |
Schistosoma mansoni | peroxidasin | 0.046 | 0.5972 | 0.594 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0054 | 0.0561 | 0.0682 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0198 | 0.2477 | 0.2415 |
Schistosoma mansoni | glutamate synthase | 0.007 | 0.077 | 0.0697 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.077 | 0.077 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.2477 | 0.2415 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0264 | 0.3357 | 0.333 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.007 | 0.077 | 0.2293 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.007 | 0.077 | 0.0429 |
Onchocerca volvulus | Peroxidasin homolog | 0.046 | 0.5972 | 0.8649 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0791 | 0.0791 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Mycobacterium tuberculosis | Probable reductase | 0.007 | 0.077 | 0.0429 |
Schistosoma mansoni | thyroid hormone receptor | 0.0148 | 0.1804 | 0.1739 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0054 | 0.0561 | 0.0522 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | matrixin family protein | 0.0479 | 0.6223 | 0.6192 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0054 | 0.0561 | 0.0459 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.007 | 0.077 | 0.1378 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.046 | 0.5972 | 0.8649 |
Brugia malayi | hypothetical protein | 0.0155 | 0.19 | 0.1781 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.007 | 0.077 | 0.077 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0041 | 0.0388 | 0.0248 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.007 | 0.077 | 0.0635 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0054 | 0.0561 | 0.0423 |
Onchocerca volvulus | Peroxidasin homolog | 0.046 | 0.5972 | 0.8649 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.007 | 0.077 | 0.1378 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.007 | 0.077 | 0.0694 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0264 | 0.3357 | 1 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0155 | 0.19 | 0.19 |
Loa Loa (eye worm) | animal heme peroxidase | 0.046 | 0.5972 | 0.5939 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1174 | 0.1101 |
Onchocerca volvulus | 0.046 | 0.5972 | 0.8649 | |
Loa Loa (eye worm) | programmed cell death 8 | 0.007 | 0.077 | 0.0694 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0264 | 0.3357 | 0.333 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.007 | 0.077 | 0.2293 |
Schistosoma mansoni | glutamate synthase | 0.007 | 0.077 | 0.0697 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.0356 | 0.0356 |
Trichomonas vaginalis | glutamate synthase, putative | 0.007 | 0.077 | 0.2293 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.007 | 0.077 | 0.0429 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.01 | 0.1174 | 0.1045 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.0356 | 0.0277 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0054 | 0.0561 | 0.0486 |
Toxoplasma gondii | thioredoxin reductase | 0.0762 | 1 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0155 | 0.19 | 0.19 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0325 | 0.4164 | 1 |
Echinococcus multilocularis | geminin | 0.0368 | 0.4742 | 0.4665 |
Brugia malayi | Peptidase family M1 containing protein | 0.0155 | 0.19 | 0.1781 |
Echinococcus granulosus | peroxidasin | 0.046 | 0.5972 | 0.5913 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.6123 | 0.6091 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0054 | 0.0561 | 0.0561 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0054 | 0.0561 | 0.0483 |
Echinococcus granulosus | geminin | 0.0368 | 0.4742 | 0.4665 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.0277 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.01 | 0.1174 | 0.1103 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.007 | 0.077 | 0.0732 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.007 | 0.077 | 0.1378 |
Trypanosoma brucei | hypothetical protein, conserved | 0.007 | 0.077 | 0.077 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.007 | 0.077 | 0.077 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0264 | 0.3357 | 0.3286 |
Loa Loa (eye worm) | animal heme peroxidase | 0.046 | 0.5972 | 0.5939 |
Onchocerca volvulus | 0.0198 | 0.2477 | 0.3266 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0356 | 0.1061 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0762 | 1 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0264 | 0.3357 | 0.326 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.007 | 0.077 | 0.2293 |
Brugia malayi | hypothetical protein | 0.046 | 0.5972 | 0.5913 |
Loa Loa (eye worm) | matrixin family protein | 0.044 | 0.5695 | 0.566 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.007 | 0.077 | 0.0635 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0155 | 0.19 | 0.5142 |
Onchocerca volvulus | Protein cereblon homolog | 0.0325 | 0.4164 | 0.5865 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.007 | 0.077 | 0.077 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.0356 | 0.0316 |
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.0356 | 0.1061 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0241 | 0.3053 | 0.2796 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0155 | 0.19 | 0.19 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0264 | 0.3357 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.046 | 0.5972 | 0.8649 |
Echinococcus multilocularis | glutamate synthase | 0.007 | 0.077 | 0.0635 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0264 | 0.3357 | 0.3328 |
Brugia malayi | hypothetical protein | 0.0132 | 0.1597 | 0.1475 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.007 | 0.077 | 0.2293 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.2477 | 0.2415 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0264 | 0.3357 | 0.3112 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.007 | 0.077 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.007 | 0.077 | 0.1378 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0264 | 0.3357 | 1 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.007 | 0.077 | 0.0732 |
Schistosoma mansoni | peroxidasin | 0.046 | 0.5972 | 0.594 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.077 | 0.077 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0054 | 0.0561 | 0.0522 |
Mycobacterium ulcerans | ferredoxin reductase | 0.007 | 0.077 | 0.1378 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0198 | 0.2477 | 0.2417 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.077 | 0.077 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0762 | 1 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0041 | 0.0388 | 0.0248 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.007 | 0.077 | 0.077 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.007 | 0.077 | 0.077 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.007 | 0.077 | 0.1849 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.007 | 0.077 | 0.0429 |
Plasmodium falciparum | thioredoxin reductase | 0.0762 | 1 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0264 | 0.3357 | 0.3112 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.007 | 0.077 | 0.0429 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0054 | 0.0561 | 0.0486 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.007 | 0.077 | 0.0635 |
Onchocerca volvulus | 0.046 | 0.5972 | 0.8649 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.007 | 0.077 | 0.2293 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0054 | 0.0561 | 0.0561 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0155 | 0.19 | 0.19 |
Schistosoma mansoni | hypothetical protein | 0.0281 | 0.3581 | 0.353 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0356 | 0.1061 |
Brugia malayi | Animal haem peroxidase family protein | 0.046 | 0.5972 | 0.5913 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.007 | 0.077 | 0.2293 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.0277 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0155 | 0.19 | 0.5658 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.007 | 0.077 | 0.1849 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.007 | 0.077 | 0.0671 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.007 | 0.077 | 0.0429 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0721 | 0.9441 | 0.9433 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0264 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1174 | 0.1101 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0264 | 0.3357 | 0.3305 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.007 | 0.077 | 0.1378 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.01 | 0.1174 | 0.1174 |
Schistosoma mansoni | hypothetical protein | 0.0368 | 0.4742 | 0.47 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0054 | 0.0561 | 0.0519 |
Brugia malayi | Peptidase family M1 containing protein | 0.0526 | 0.6849 | 0.6803 |
Brugia malayi | Thioredoxin reductase | 0.0762 | 1 | 1 |
Brugia malayi | Peptidase family M1 containing protein | 0.0054 | 0.0561 | 0.0423 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0356 | 0.1061 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.077 | 0.077 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.007 | 0.077 | 0.1378 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.007 | 0.077 | 0.0635 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0054 | 0.0561 | 0.0486 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.007 | 0.077 | 0.0429 |
Onchocerca volvulus | Peroxidase homolog | 0.046 | 0.5972 | 0.8649 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0155 | 0.19 | 0.1781 |
Entamoeba histolytica | aminopeptidase, putative | 0.0155 | 0.19 | 0.4562 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.007 | 0.077 | 0.0729 |
Schistosoma mansoni | glutamate synthase | 0.007 | 0.077 | 0.0697 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.0356 | 0.0215 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0264 | 0.3357 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.0356 | 0.1061 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.007 | 0.077 | 0.0429 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.007 | 0.077 | 0.0732 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0155 | 0.19 | 0.19 |
Trypanosoma brucei | NADH dehydrogenase | 0.007 | 0.077 | 0.077 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0137 | 0.1658 | 0.1536 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.007 | 0.077 | 0.1378 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.007 | 0.077 | 0.1849 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.007 | 0.077 | 0.0671 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0264 | 0.3357 | 0.3112 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0155 | 0.19 | 0.1835 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | aminopeptidase N | 0.0155 | 0.19 | 0.1833 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.077 | 0.1378 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0762 | 1 | 1 |
Onchocerca volvulus | 0.0155 | 0.19 | 0.2377 | |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.007 | 0.077 | 0.1849 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0054 | 0.0561 | 0.0423 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.007 | 0.077 | 0.077 |
Brugia malayi | hypothetical protein | 0.0054 | 0.0561 | 0.0423 |
Onchocerca volvulus | 0.0281 | 0.3581 | 0.4967 | |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.007 | 0.077 | 0.077 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.077 | 0.2293 |
Echinococcus multilocularis | peroxidasin | 0.046 | 0.5972 | 0.5913 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0054 | 0.0561 | 0.0561 |
Brugia malayi | follicle stimulating hormone receptor | 0.0252 | 0.3188 | 0.3089 |
Leishmania major | trypanothione reductase | 0.0762 | 1 | 1 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0721 | 0.9441 | 0.9433 |
Leishmania major | NADH dehydrogenase, putative | 0.007 | 0.077 | 0.077 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0054 | 0.0561 | 0.0519 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0264 | 0.3357 | 0.3112 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0264 | 0.3357 | 0.326 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0054 | 0.0561 | 0.0459 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.007 | 0.077 | 0.1849 |
Onchocerca volvulus | Dual oxidase homolog | 0.046 | 0.5972 | 0.8649 |
Loa Loa (eye worm) | RecQ helicase | 0.0023 | 0.0144 | 0.0063 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0264 | 0.3357 | 0.3357 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0264 | 0.3357 | 0.3357 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0072 | 0.0791 | 0.0656 |
Plasmodium falciparum | glutathione reductase | 0.0264 | 0.3357 | 0.3286 |
Trypanosoma brucei | trypanothione reductase | 0.0762 | 1 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0264 | 0.3357 | 0.3286 |
Brugia malayi | Matrixin family protein | 0.0479 | 0.6223 | 0.6168 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.007 | 0.077 | 0.2293 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0155 | 0.19 | 0.19 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.0356 | 0.0215 |
Loa Loa (eye worm) | glutathione reductase | 0.0762 | 1 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0264 | 0.3357 | 0.3328 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.007 | 0.077 | 0.1378 |
Onchocerca volvulus | Matrilysin homolog | 0.0198 | 0.2477 | 0.3266 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.007 | 0.077 | 0.077 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.3053 | 0.2996 |
Mycobacterium ulcerans | dehydrogenase | 0.007 | 0.077 | 0.1378 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.007 | 0.077 | 0.077 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.007 | 0.077 | 0.1378 |
Mycobacterium ulcerans | monoxygenase | 0.007 | 0.077 | 0.1378 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.0356 | 0.028 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0194 | 0.2422 | 0.2312 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.0356 | 0.1061 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.007 | 0.077 | 0.1378 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0762 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.2477 | 0.2415 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0054 | 0.0561 | 0.0561 |
Toxoplasma gondii | selenide, water dikinase | 0.007 | 0.077 | 0.0732 |
Onchocerca volvulus | Matrilysin homolog | 0.044 | 0.5695 | 0.8223 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.0277 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.025 | 0.3165 | 0.2913 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Plasmodium falciparum | glutathione reductase | 0.0762 | 1 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0194 | 0.2422 | 0.2312 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0072 | 0.0791 | 0.0791 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0072 | 0.0791 | 0.0715 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0426 | 0.551 | 0.5473 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.007 | 0.077 | 0.2293 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0137 | 0.1658 | 0.1536 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0072 | 0.0791 | 0.0656 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.007 | 0.077 | 0.077 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0155 | 0.19 | 0.19 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0023 | 0.0144 | 0.0429 |
Plasmodium vivax | glutathione reductase, putative | 0.0762 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.4428 | 0.4383 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.007 | 0.077 | 0.0635 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.007 | 0.077 | 0.0732 |
Brugia malayi | Animal haem peroxidase family protein | 0.046 | 0.5972 | 0.5913 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.007 | 0.077 | 0.2293 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.0356 | 0.0215 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0072 | 0.0791 | 0.0791 |
Brugia malayi | Matrixin family protein | 0.0198 | 0.2477 | 0.2367 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.007 | 0.077 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0356 | 0.0277 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0054 | 0.0561 | 0.0483 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.077 | 0.0697 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.007 | 0.077 | 0.0429 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.007 | 0.077 | 0.0635 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0023 | 0.0144 | 0.0429 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0264 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | animal heme peroxidase | 0.046 | 0.5972 | 0.5939 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0264 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.046 | 0.5972 | 0.5939 |
Brugia malayi | Hemopexin family protein | 0.0281 | 0.3581 | 0.3487 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0561 | 0.0483 |
Onchocerca volvulus | 0.0054 | 0.0561 | 0.0315 | |
Brugia malayi | Animal haem peroxidase family protein | 0.046 | 0.5972 | 0.5913 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0471 | 0.611 | 0.6079 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0241 | 0.3053 | 0.8985 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0561 | 0.0483 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0264 | 0.3357 | 1 |
Brugia malayi | beta-lactamase | 0.0039 | 0.0356 | 0.0215 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0264 | 0.3357 | 0.326 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0264 | 0.3357 | 1 |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.007 | 0.077 | 0.1378 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.007 | 0.077 | 0.1378 |
Schistosoma mansoni | hypothetical protein | 0.0137 | 0.1658 | 0.1591 |
Onchocerca volvulus | 0.007 | 0.077 | 0.0637 | |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0155 | 0.19 | 0.5658 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.007 | 0.077 | 0.0635 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0054 | 0.0561 | 0.0423 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.007 | 0.077 | 0.0635 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0264 | 0.3357 | 1 |
Brugia malayi | Peroxidasin | 0.046 | 0.5972 | 0.5913 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0252 | 0.3188 | 0.3133 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.5972 | 0.5939 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0264 | 0.3357 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0155 | 0.19 | 0.19 |
Schistosoma mansoni | hypothetical protein | 0.0368 | 0.4742 | 0.47 |
Brugia malayi | Animal haem peroxidase family protein | 0.046 | 0.5972 | 0.5913 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.007 | 0.077 | 0.0732 |
Brugia malayi | Blistered cuticle protein 3 | 0.046 | 0.5972 | 0.5913 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.007 | 0.077 | 0.0635 |
Brugia malayi | Matrixin family protein | 0.0198 | 0.2477 | 0.2367 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.4164 | 0.4116 |
Echinococcus granulosus | aminopeptidase N | 0.0526 | 0.6849 | 0.6803 |
Treponema pallidum | NADH oxidase | 0.0264 | 0.3357 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0264 | 0.3357 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0155 | 0.19 | 0.1781 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.0356 | 0.0356 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.007 | 0.077 | 0.0635 |
Brugia malayi | Matrixin family protein | 0.0198 | 0.2477 | 0.2367 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0072 | 0.0791 | 0.1899 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.